All Stories

  1. Conformational Heterogeneity and Redox Switching of the Cysteine Residues in SARS-CoV-2 Main Protease: A Raman Molecular Fingerprint
  2. Engineering intermolecular charge transfer in covalent organic frameworks for photocatalytic hydrogen peroxide generation
  3. Dynamic claw of dengue protease unveils druggability potential with high affinity allosteric inhibitors
  4. Gelatinase-Responsive Short Peptide Conjugate as a Precision Therapy Against Methicillin-Resistant Staphylococcus aureus
  5. Engineering Intermolecular Charge Transfer in Covalent Organic Frameworks for Photocatalytic Hydrogen Peroxide Generation
  6. A Dimolybdenum Paddlewheel Embedded Covalent Organic Framework for Photocatalytic Hydrogen Peroxide Generation
  7. Combating Fuel Biocontamination: Tailored Antimicrobial Peptides and an Innovative Delivery Strategy
  8. Morin Interacts with α-Synuclein and Retards Its Fibrillation
  9. Stabilization of α-Helical Folded Structures Retards Hydrophobic Zipping and Fibrillation of Bovine Insulin: A Key Signature from Raman Spectroscopic Analysis
  10. Mercury Can Bond to α-Carbon of Curcumin Increasing Stability in Aqueous Medium and Demonstrated Selective Cytotoxicity against Acute Leukemia
  11. Diketopyrrolopyrrole‐based Donor–Acceptor Covalent Organic Frameworks for Iodine Capture
  12. Enhancing photocatalytic hydrogen peroxide generation by tuning hydrazone linkage density in covalent organic frameworks
  13. Engineering donor-functionalized covalent organic frameworks to promote photocatalytic hydrogen peroxide generation
  14. Microtubule-Targeting NAP Peptide-Ru(II)-polypyridyl Conjugate As a Bimodal Therapeutic Agent for Triple Negative Breast Carcinoma
  15. Dengue Protease-Mediated Activation and Polarization of Macrophages
  16. Structure–function analysis of nucleotide housekeeping protein HAM1 from human malaria parasite Plasmodium falciparum
  17. Flame retardant tetrabromobisphenol A (TBBPA) disrupts histone acetylation during zebrafish maternal-to-zygotic transition
  18. Drug Discovery Approaches Targeting Dengue NS2B/NS3 Protease
  19. Exploring Medical Biotechnology- in vivo, in vitro, in silico
  20. Introduction
  21. Network Pharmacology as a Potential Tool to Unlock the Treasure Trove of Pharmaceuticals in Natural Products
  22. Theranostic Application of Nanomaterial in Human Health and Disease
  23. Therapeutics for Neurodegenerative Diseases
  24. Metal-Free Activation of Molecular Oxygen by Quaternary Ammonium-Based Ionic Liquid: A Detail Mechanistic Study
  25. Raman Spectroscopic Insights of Phase-Separated Insulin Aggregates
  26. Cell-Derived Exosome-Based Materials for Biomedical Applications
  27. Frontiers in Chemistry: Rising Stars 2022
  28. COVID-19 therapeutics: Clinical application of repurposed drugs and futuristic strategies for target-based drug discovery
  29. Single point mutations at the S129 residue of α-synuclein and their effect on structure, aggregation, and neurotoxicity
  30. Newly Synthesized 3-Indolyl Furanoid Inhibits Matrix Metalloproteinase-9 Activity and Prevents Nonsteroidal Anti-inflammatory Drug-Induced Gastric Ulceration
  31. Naringenin-Functionalized Gold Nanoparticles and Their Role in α-Synuclein Stabilization
  32. Loop Dynamics and Conformational Flexibility in Dengue Serine Protease Activity: Noninvasive Perturbation by Solvent Exchange
  33. Cell-Derived Exosome-Based Materials for Biomedical Applications
  34. Cell-Derived Exosome-Based Materials for Biomedical Applications
  35. NMR and vibrational spectroscopic studies on the structure and self-assembly of Two de novo dipeptides in methanol
  36. Reversible photoswitching of spiropyran in biomolecular interfaces: A combined spectroscopy and computational study
  37. A combined spectroscopic and molecular modeling Study on structure-function-dynamics under chemical modification: Alpha-chymotrypsin with formalin preservative
  38. Regio- and stereoselectivity of the 1,3-dipolar cycloaddition of azomethine ylides to (E)-3-(2-oxo-2-(pyren-1-yl)ethylidene)indolin-2-ones: A combined experimental and theoretical study
  39. Host‐Assisted Delivery of a Model Drug to Genomic DNA: Key Information from Ultrafast Spectroscopy and in silico Study
  40. Omeprazole prevents stress induced gastric ulcer by direct inhibition of MMP-2/TIMP-3 interactions
  41. Fabrication of nanohybrids toward improving therapeutic potential of a NIR photo-sensitizer: An optical spectroscopic and computational study
  42. Piezo-phototronic effect in highly stable CsPbI3-PVDF composite for self-powered nanogenerator and photodetector
  43. Essential Loop Dynamics Modulates Catalytic Activity in α‐Chymotrypsin
  44. Effect of a Metal Ion in Modulating the Binding Interaction of a Dietary Flavonoid with Bovine Serum Albumin and DNA: A Spectroscopic and Theoretical Approach
  45. Evaluation of therapeutic effect of Premna herbacea in diabetic rat and isoverbascoside against insulin resistance in L6 muscle cells through bioenergetics and stimulation of JNK and AKT/mTOR signaling cascade
  46. In vitro and Microbiological Assay of Functionalized Hybrid Nanomaterials To Validate Their Efficacy in Nanotheranostics: A Combined Spectroscopic and Computational Study
  47. Dabrafenib, idelalisib and nintedanib act as significant allosteric modulator for dengue NS3 protease
  48. Extraction behavior of yttrium with Aliquat336 from nitrate and thiocyanate media: A microscopic view from computational analysis
  49. Essential Loop Dynamics Modulates Catalytic Activity in α-Chymotrypsin
  50. A Combined Spectroscopic and Molecular Modeling Study on Structure-Function-Dynamics under Chemical Modification: Alpha-Chymotrypsin with Formalin Preservative
  51. Development of Triboelectroceutical Fabrics for Potential Applications in Self-Sanitizing Personal Protective Equipment
  52. Nanoceutical Fabric Prevents COVID-19 Spread through Expelled Respiratory Droplets: A Combined Computational, Spectroscopic, and Antimicrobial Study
  53. Effect of Mg Doping on Structural, Alloying, Electronic, Optical, and Bactericidal Properties of CunAg25–n Nanoclusters: A Computational Study
  54. Effect of solvent on the photophysical properties of isoxazole derivative of curcumin: A combined spectroscopic and theoretical study
  55. Host assisted molecular recognition by human serum albumin: Study of molecular recognition controlled protein/drug mimic binding in a microfluidic channel
  56. Intriguing Biomedical Applications of Synthetic and Natural Cell-Derived Vesicles: A Comparative Overview
  57. Development of Tribo-Electroceutical Fabrics for Potential Application in Self-sanitizing Personal Protective Equipment (PPE)
  58. Nanoceutical Fabric Prevents COVID-19 Spread through Expelled Respiratory Droplets: A Combined Computational, Spectroscopic and Anti-microbial Study
  59. Impact of porous nanomaterials on inhibiting protein aggregation behaviour
  60. Biophysical and theoretical studies of the interaction between a bioactive compound 3,5-dimethoxy-4-hydroxycinnamic acid with calf thymus DNA
  61. The Role of Imidazolium-Based Surface-Active Ionic Liquid to Restrain the Excited-State Intramolecular H-Atom Transfer Dynamics of Medicinal Pigment Curcumin: A Theoretical and Experimental Approach
  62. Incorporation of a Biocompatible Nanozyme in Cellular Antioxidant Enzyme Cascade Reverses Huntington’s Like Disorder in Preclinical Model
  63. Unprecedented Regio- and Stereoselective Synthesis of Pyrene-Grafted Dispiro[indoline-3,2′-pyrrolidine-3′,3″-indolines]: Expedient Experimental and Theoretical Insights into Polar [3 + 2] Cycloaddition
  64. Interaction of proflavin with tryptophan in reverse micellar microenvironment of AOT: Photoinduced electron transfer probed by magnetic field effect
  65. Porphyrin-Armored Gold Nanospheres Modulate the Secondary Structure of α-Synuclein and Arrest Its Fibrillation
  66. Probing the Hydrogen Bond Involving Acridone Trapped in a Hydrophobic Biological Nanocavity: Integrated Spectroscopic and Docking Analyses
  67. Flexibility modulates the catalytic activity of a thermostable enzyme: key information from optical spectroscopy and molecular dynamics simulation
  68. Wide bandgap semiconductor-based novel nanohybrid for potential antibacterial activity: ultrafast spectroscopy and computational studies
  69. Order, Disorder, and Reorder State of Lysozyme: Aggregation Mechanism by Raman Spectroscopy
  70. Multi-spectroscopic and computational evaluation on the binding of sinapic acid and its Cu(II) complex with bovine serum albumin
  71. Preferential photochemical interaction of Ru (III) doped carbon nano dots with bovine serum albumin over human serum albumin
  72. Selective and Fast Responsive Sensitized Micelle for Detection of Fluoride Level in Drinking Water
  73. Stimuli-Responsive Nanocapsules for the Spatiotemporal Release of Melatonin: Protection against Gastric Inflammation
  74. Wide Range Morphological Transition of Silver Nanoprisms by Selective Interaction with As(III): Tuning–Detuning of Surface Plasmon Offers To Decode the Mechanism
  75. Encapsulation of Thymol in cyclodextrin nano-cavities: A multi spectroscopic and theoretical study
  76. Sensing of Iron(III) Ion via Modulation of Redox Potential on Biliverdin Protected Silver Nanosurface
  77. Design and Synthesis of Fluorescent Carbon-Dot Polymer and Deciphering Its Electronic Structure
  78. Low Magnetic Field Induced Surface Enhanced Transient Spin-Trajectory Modulation of a Prototype Anticancer Drug Sanguinarine on a Single Domain Superparamagnetic Nanosurface
  79. Advances in the Application of Nanomaterials and Nanosacled Materials in Physiology or Medicine: Now and the Future
  80. Curcumin stably interacts with DNA hairpin through minor groove binding and demonstrates enhanced cytotoxicity in combination with FdU nucleotides
  81. Structural Insight of Amyloidogenic Intermediates of Human Insulin
  82. Nuclear Uptake of Thiolated Riboflavin Gold Nanoassembly: DNA Damage and Apoptosis Induction in Cancer Cell
  83. DNA Damage and Apoptosis Induction in Cancer Cells by Chemically Engineered Thiolated Riboflavin Gold Nanoassembly
  84. Mesoporous silica for drug delivery: Interactions with model fluorescent lipid vesicles and live cells
  85. Crystal-defect-induced facet-dependent electrocatalytic activity of 3D gold nanoflowers for the selective nanomolar detection of ascorbic acid
  86. Correction: Crystal-defect-induced facet-dependent electrocatalytic activity of 3D gold nanoflowers for the selective nanomolar detection of ascorbic acid
  87. Formation of Annular Protofibrillar Assembly by Cysteine Tripeptide: Unraveling the Interactions with NMR, FTIR, and Molecular Dynamics
  88. Tamarixetin 3-O-β-d-Glucopyranoside from Azadirachta indica Leaves: Gastroprotective Role through Inhibition of Matrix Metalloproteinase-9 Activity in Mice
  89. Constrained Photophysics of 5,7-dimethoxy-2,3,4,9-tetrahydro-1H-carbazol-1-one in the Bioenvironment of Serum Albumins: A Spectroscopic Endeavour Supported by Molecular Docking Analysis
  90. Evidence of two structurally related solvatochromic probes complexed with β-cyclodextrin by using spectroscopic methods
  91. Acridone in a biological nanocavity: detailed spectroscopic and docking analyses of probing both the tryptophan residues of bovine serum albumin
  92. Envisaging Structural Insight of a Terminally Protected Proline Dipeptide by Raman Spectroscopy and Density Functional Theory Analyses
  93. Orientation of tyrosine side chain in neurotoxic Aβ differs in two different secondary structures of the peptide
  94. Silver-catalysed azide–alkyne cycloaddition (AgAAC): assessing the mechanism by density functional theory calculations
  95. A Novel Spirooxindole Derivative Inhibits the Growth of Leishmania donovani Parasites bothIn VitroandIn Vivoby Targeting Type IB Topoisomerase
  96. Binding interaction of a gamma-aminobutyric acid derivative with serum albumin: an insight by fluorescence and molecular modeling analysis
  97. Molecular Details of Acetate Binding to a New Diamine Receptor by NMR and FT-IR Analyses
  98. Identification of modes of interactions between 9-aminoacridine hydrochloride hydrate and serum proteins by low and high resolution spectroscopy and molecular modeling
  99. Metal ions provide structural stability and compactness to tetrameric purothionin
  100. Conformational selection underpins recognition of multiple DNA sequences by proteins and consequent functional actions
  101. Binding interaction of a novel fluorophore with serum albumins: steady state fluorescence perturbation and molecular modeling analysis
  102. ChemInform Abstract: Stereoselective Domino Azidation and [3 + 2] Cycloaddition: A Facile Route to Chiral Heterocyclic Scaffolds from Carbohydrate Derived Synthons.
  103. Sequence Complexity of Amyloidogenic Regions in Intrinsically Disordered Human Proteins
  104. C α –H Carries Information of a Hydrogen Bond Involving the Geminal Hydroxyl Group: A Case Study with a Hydrogen-Bonded Complex of 1,1,1,3,3,3-Hexafluoro-2-propanol and Tertiary Amines
  105. pKa Determination of d-Ribose by Raman Spectroscopy
  106. Stereoselective domino azidation and [3 + 2] cycloaddition: a facile route to chiral heterocyclic scaffolds from carbohydrate derived synthons
  107. Binding of hemoglobin to ultrafine carbon nanoparticles: a spectroscopic insight into a major health hazard
  108. Copper(I) oxide nanoparticle and tryptophan as its biological conjugate: a modulation of cytotoxic effects
  109. 2,2′-Diphenyl-3,3′-Diindolylmethane: A Potent Compound Induces Apoptosis in Breast Cancer Cells by Inhibiting EGFR Pathway
  110. Melatonin inhibits matrix metalloproteinase-9 activity by binding to its active site
  111. Potent anticancer activity of cystine-based dipeptides and their interaction with serum albumins
  112. Dipeptide derived from benzylcystine forms unbranched nanotubes in aqueous solution
  113. Nickel(II)-Schiff base complex recognizing domain II of bovine and human serum albumin: Spectroscopic and docking studies
  114. Novel Anti-inflammatory Activity of Epoxyazadiradione against Macrophage Migration Inhibitory Factor: INHIBITION OF TAUTOMERASE AND PROINFLAMMATORY ACTIVITIES OF MACROPHAGE MIGRATION INHIBITORY FACTOR
  115. Interaction of Merocyanine 540 with serum albumins: Photophysical and binding studies
  116. Conformation and cytotoxicity of a tetrapeptide constellated with alternative d- and l-proline
  117. Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent