All Stories

  1. Potent acyl-CoA synthetase 10 inhibitors kill Plasmodium falciparum by disrupting triglyceride formation

    Article • Nature Communications, March 2023, Springer Science + Business Media

    Dr Sumanta Dey

  2. The anticancer human mTOR inhibitor sapanisertib potently inhibits multiple Plasmodium kinases and life cycle stages

    Article • Science Translational Medicine, October 2022, American Association for the Advancement of Science

    Dr Sumanta Dey

  3. Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy

    Article • Science, June 2022, American Association for the Advancement of Science

    Dr Sumanta Dey

  4. The Plasmodium falciparum ABC transporter ABCI3 confers parasite strain-dependent pleiotropic antimalarial drug resistance

    Article • Cell Chemical Biology, May 2022, Elsevier

    Dr Sumanta Dey

  5. GeneTargeter: Automated In Silico Design for Genome Editing in the Malaria Parasite, Plasmodium falciparum

    Article • The CRISPR Journal, February 2022, SAGE Publications

    Dr Sumanta Dey

  6. Repositioning and Characterization of 1-(Pyridin-4-yl)pyrrolidin-2-one Derivatives as Plasmodium Cytoplasmic Prolyl-tRNA Synthetase Inhibitors

    Article • ACS Infectious Diseases, April 2021, American Chemical Society (ACS)

    Prof. Dr. RAFAEL VICTORIO CARVALHO GUIDO, Dr Sumanta Dey

  7. Translocation of heme oxygenase-1 to mitochondria is a novel cytoprotective mechanism against non-steroidal anti-inflammatory drug-induced mitochondrial oxidative stress, apoptosis, and gastric mucosal injury.

    Article • Journal of Biological Chemistry, May 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Sumanta Dey

  8. Heme oxygenase 1 and liver function in malaria infected mice

    Article • Infection and Immunity, May 2014, ASM Journals

    Dr Sumanta Dey

  9. Nonsteroidal anti-inflammatory drug induces proinflammatory damage in gastric mucosa through NF-κB activation and neutrophil infiltration: Anti-inflammatory role of heme oxygenase-1 against nonsteroidal anti-inflammatory drug

    Article • Free Radical Biology and Medicine, December 2013, Elsevier

    Dr Sumanta Dey

  10. Aryl aryl methyl thio arenes prevent multidrug-resistant malaria in mouse by promoting oxidative stress in parasites

    Article • Free Radical Biology and Medicine, July 2012, Elsevier

    Dr Sumanta Dey

  11. Impact of Intravascular Hemolysis in Malaria on Liver Dysfunction: INVOLVEMENT OF HEPATIC FREE HEME OVERLOAD, NF- B ACTIVATION, AND NEUTROPHIL INFILTRATION

    Article • Journal of Biological Chemistry, June 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Sumanta Dey

  12. Novel Anti-inflammatory Activity of Epoxyazadiradione against Macrophage Migration Inhibitory Factor: INHIBITION OF TAUTOMERASE AND PROINFLAMMATORY ACTIVITIES OF MACROPHAGE MIGRATION INHIBITORY FACTOR

    Article • Journal of Biological Chemistry, May 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Sumanta Dey, Dr Uttam Pal

  13. Tryptamine-Gallic Acid Hybrid Prevents Non-steroidal Anti-inflammatory Drug-induced Gastropathy: CORRECTION OF MITOCHONDRIAL DYSFUNCTION AND INHIBITION OF APOPTOSIS IN GASTRIC MUCOSAL CELLS

    Article • Journal of Biological Chemistry, December 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Sumanta Dey

  14. Synthesis and bio-evaluation of human macrophage migration inhibitory factor inhibitor to develop anti-inflammatory agent

    Article • Bioorganic & Medicinal Chemistry, December 2011, Elsevier

    Dr Sumanta Dey, Dr Uttam Pal

  15. Identification and molecular characterization of an Alba-family protein from human malaria parasite Plasmodium falciparum

    Article • Nucleic Acids Research, October 2011, Oxford University Press (OUP)

    Dr Sumanta Dey

  16. Translocation of Heme Oxygenase-1 to Mitochondria Is a Novel Cytoprotective Mechanism against Non-steroidal Anti-inflammatory Drug-induced Mitochondrial Oxidative Stress, Apoptosis, and Gastric Mucosal Injury

    Article • Journal of Biological Chemistry, September 2011, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Sumanta Dey

  17. Cysteine-3 and cysteine-4 are essential for the thioredoxin-like oxidoreductase and antioxidant activities of Plasmodium falciparum macrophage migration inhibitory factor

    Article • Free Radical Biology and Medicine, June 2011, Elsevier

    Dr Sumanta Dey

  18. Antimalarial Drugs and Molecules Inhibiting Hemozoin Formation

    Article • February 2011, Wiley

    Dr Sumanta Dey

  19. Gallic acid prevents nonsteroidal anti-inflammatory drug-induced gastropathy in rat by blocking oxidative stress and apoptosis

    Article • Free Radical Biology and Medicine, July 2010, Elsevier

    Dr Sumanta Dey

  20. Novel antimalarial drug targets: hope for new antimalarial drugs

    Article • Expert Review of Clinical Pharmacology, September 2009, Taylor & Francis

    Dr Sumanta Dey

  21. Melatonin reduces indomethacin-induced gastric mucosal cell apoptosis by preventing mitochondrial oxidative stress and the activation of mitochondrial pathway of apoptosis

    Article • Journal of Pineal Research, April 2009, Wiley

    Dr Sumanta Dey

  22. Malarial infection develops mitochondrial pathology and mitochondrial oxidative stress to promote hepatocyte apoptosis

    Article • Free Radical Biology and Medicine, January 2009, Elsevier

    Dr Sumanta Dey

  23. Indomethacin, a Non-steroidal Anti-inflammatory Drug, Develops Gastropathy by Inducing Reactive Oxygen Species-mediated Mitochondrial Pathology and Associated Apoptosis in Gastric Mucosa: A NOVEL ROLE OF MITOCHONDRIAL ACONITASE OXIDATION

    Article • Journal of Biological Chemistry, December 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Sumanta Dey

  24. Lansoprazole Protects and Heals Gastric Mucosa from Non-steroidal Anti-inflammatory Drug (NSAID)-induced Gastropathy by Inhibiting Mitochondrial as Well as Fas-mediated Death Pathways with Concurrent Induction of Mucosal Cell Renewal

    Article • Journal of Biological Chemistry, March 2008, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Sumanta Dey