All Stories

  1. Acute, controlled inhalation of thin graphene oxide nanosheets in humans with null cardiorespiratory effects
  2. Recent progress in the EU classification of the health hazards associated with certain multiwall carbon nanotubes (MWCNTs): what about the other MWCNTs?
  3. Re-evaluation of the occupational exposure limit for ZnO is warranted. Comments on 'Systemic inflammatory effects of zinc oxide particles: is a re-evaluation of exposure limits needed?' by Christian Monsé et al.
  4. Lessons from nanosafety research for effective regulation and safer handling of nanomaterials at the workplace
  5. Toxicity dose descriptors from animal inhalation studies of 13 nanomaterials and their bulk and ionic counterparts and variation with primary particle characteristics
  6. Polymorphisms within Autophagy-Related Genes as Susceptibility Biomarkers for Multiple Myeloma: A Meta-Analysis of Three Large Cohorts and Functional Characterization
  7. Single-Walled vs. Multi-Walled Carbon Nanotubes: Influence of Physico-Chemical Properties on Toxicogenomics Responses in Mouse Lungs
  8. Predicting nanomaterials pulmonary toxicity in animals by cell culture models: Achievements and perspectives
  9. Assessment of primary and inflammation-driven genotoxicity of carbon black nanoparticles in vitro and in vivo
  10. The Use of Human Biomonitoring to Assess Occupational Exposure to PAHs in Europe: A Comprehensive Review
  11. Characterization of ENM Dynamic Dose-Dependent MOA in Lung with Respect to Immune Cells Infiltration
  12. AOP173 key event associated pathway predictor – online application for the prediction of benchmark dose lower bound (BMDLs) of a transcriptomic pathway involved in MWCNTs-induced lung fibrosis
  13. The influence of exposure approaches to in vitro lung epithelial barrier models to assess engineered nanomaterial hazard
  14. Pro-inflammatory response and genotoxicity caused by clay and graphene nanomaterials in A549 and THP-1 cells
  15. Nanomaterial- and shape-dependency of TLR2 and TLR4 mediated signaling following pulmonary exposure to carbonaceous nanomaterials in mice
  16. Lead (Pb) and neurodevelopment: A review on exposure and biomarkers of effect (BDNF, HDL) and susceptibility
  17. Effect on Mouse Liver Morphology of CeO2, TiO2 and Carbon Black Nanoparticles Translocated from Lungs or Deposited Intravenously
  18. Inflammatory Response, Reactive Oxygen Species Production and DNA Damage in Mice After Intrapleural Exposure to Carbon Nanotubes
  19. Transcriptomics‐Based and AOP‐Informed Structure–Activity Relationships to Predict Pulmonary Pathology Induced by Multiwalled Carbon Nanotubes
  20. A response to the letter to the editor by Driscoll et al.
  21. Translating Scientific Advances in the AOP Framework to Decision Making for Nanomaterials
  22. Fast and Robust Proteome Screening Platform Identifies Neutrophil Extracellular Trap Formation in the Lung in Response to Cobalt Ferrite Nanoparticles
  23. Commentary: the chronic inhalation study in rats for assessing lung cancer risk may be better than its reputation
  24. Acute phase response and inflammation following pulmonary exposure to low doses of zinc oxide nanoparticles in mice
  25. Pulmonary toxicity of two different multi-walled carbon nanotubes in rat: Comparison between intratracheal instillation and inhalation exposure
  26. No Interaction between Polymorphisms Related to Vitamin A Metabolism and Vitamin A Intake in Relation to Colorectal Cancer in a Prospective Danish Cohort
  27. Airport emission particles: exposure characterization and toxicity following intratracheal instillation in mice
  28. Health effects of exposure to diesel exhaust in diesel-powered trains
  29. FADS and PPARG2 Single Nucleotide Polymorphisms are Associated with Plasma Lipids in 9-Mo-Old Infants
  30. Methylation status of the PPP1R13L promoter region among lung cancer patients and healthy controls. Analytical cross-sectional study
  31. Exposure to Air Pollution inside Electric and Diesel-Powered Passenger Trains
  32. Effects of maternal inhalation of carbon black nanoparticles on reproductive and fertility parameters in a four-generation study of male mice
  33. Intake of Red and Processed Meat, Use of Non-Steroid Anti-Inflammatory Drugs, Genetic Variants and Risk of Colorectal Cancer: A Prospective Study of the Danish “Diet, Cancer and Health” Cohort
  34. Polymorphisms in the NFkB, TNF-alpha, IL-1beta, and IL-18 pathways are associated with response to anti-TNF therapy in Danish patients with inflammatory bowel disease
  35. Pulmonary effects of nanofibrillated celluloses in mice suggest that carboxylation lowers the inflammatory and acute phase responses
  36. Ranking of nanomaterial potency to induce pathway perturbations associated with lung responses
  37. Genetic polymorphisms in genes of class switch recombination and multiple myeloma risk and survival: an IMMEnSE study
  38. Safety Assessment of Graphene-Based Materials: Focus on Human Health and the Environment
  39. Physicochemical predictors of Multi-Walled Carbon Nanotube-induced pulmonary histopathology and toxicity one year after pulmonary deposition of 11 different Multi-Walled Carbon Nanotubes in mice
  40. Genetically determined high activities of the TNF-alpha, IL23/IL17, and NFkB pathways were associated with increased risk of ankylosing spondylitis
  41. Maternal inhalation of carbon black nanoparticles induces neurodevelopmental changes in mouse offspring
  42. Corrigendum to “MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs” [Toxicol. Appl. Pharmacol., 284 (2015) 16–32]
  43. In vivo-induced size transformation of cerium oxide nanoparticles in both lung and liver does not affect long-term hepatic accumulation following pulmonary exposure
  44. GLTSCR1, ATM, PPP1R13L and CD3EAP Genetic Variants and Lung Cancer Risk in a Chinese Population
  45. Genetic polymorphism in selenoprotein P modifies the response to selenium-rich foods on blood levels of selenium and selenoprotein P in a randomized dietary intervention study in Danes
  46. Dip coating of air purifier ceramic honeycombs with photocatalytic TiO2 nanoparticles: A case study for occupational exposure
  47. Nanofibrillated cellulose causes acute pulmonary inflammation that subsides within a month
  48. Toxicity of pristine and paint-embedded TiO2 nanomaterials
  49. Assessment of polycyclic aromatic hydrocarbon exposure, lung function, systemic inflammation, and genotoxicity in peripheral blood mononuclear cells from firefighters before and after a work shift
  50. Occupational exposure during handling and loading of halloysite nanotubes – A case study of counting nanofibers
  51. Meat and fiber intake and interaction with pattern recognition receptors (TLR1, TLR2, TLR4, and TLR10) in relation to colorectal cancer in a Danish prospective, case-cohort study
  52. Editorial: dose-dependent ZnO particle-induced acute phase response in humans warrants re-evaluation of occupational exposure limits for metal oxides
  53. Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis
  54. Pulmonary exposure to carbonaceous nanomaterials and sperm quality
  55. Primary genotoxicity in the liver following pulmonary exposure to carbon black nanoparticles in mice
  56. 19p13.3 -GADD45B common variants and 19q13.3- PPP1R13L and 19q13.3- CD3EAP in lung cancer risk among Chinese
  57. Influence of dispersion medium on nanomaterial-induced pulmonary inflammation and DNA strand breaks: investigation of carbon black, carbon nanotubes and three titanium dioxide nanoparticles
  58. Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis
  59. Association between polycyclic aromatic hydrocarbon exposure and peripheral blood mononuclear cell DNA damage in human volunteers during fire extinction exercises
  60. Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge
  61. Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework
  62. Cardiovascular health effects following exposure of human volunteers during fire extinction exercises
  63. Associations between functional polymorphisms and response to biological treatment in Danish patients with psoriasis
  64. Systematic review and meta-analysis: pharmacogenetics of anti-TNF treatment response in rheumatoid arthritis
  65. Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide
  66. Airway exposure to multi-walled carbon nanotubes disrupts the female reproductive cycle without affecting pregnancy outcomes in mice
  67. Association between single nucleotide polymorphisms in the antioxidant genes CAT, GR and SOD1, erythrocyte enzyme activities, dietary and life style factors and breast cancer risk in a Danish, prospective cohort study
  68. Interactions between SNPs affecting inflammatory response genes are associated with multiple myeloma disease risk and survival
  69. High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice
  70. Multi-walled carbon nanotube-physicochemical properties predict the systemic acute phase response following pulmonary exposure in mice
  71. Positive staining for cellulose in oral pulse granuloma
  72. Identification of Gene Transcription Start Sites and Enhancers Responding to Pulmonary Carbon Nanotube Exposure in Vivo
  73. Fibrillar vs crystalline nanocellulose pulmonary epithelial cell responses: Cytotoxicity or inflammation?
  74. Promise and peril in nanomedicine: the challenges and needs for integrated systems biology approaches to define health risk
  75. Biodistribution of Carbon Nanotubes in Animal Models
  76. Genetically determined high activity of IL-12 and IL-18 in ulcerative colitis and TLR5 in Crohns disease were associated with non-response to anti-TNF therapy
  77. In Vitro Toxicity Evaluation of Lignin-(Un)coated Cellulose Based Nanomaterials on Human A549 and THP-1 Cells
  78. Identification of miRSNPs associated with the risk of multiple myeloma
  79. Confirmation of an IRAK3 polymorphism as a genetic marker predicting response to anti-TNF treatment in rheumatoid arthritis
  80. Surface modification does not influence the genotoxic and inflammatory effects of TiO2nanoparticles after pulmonary exposure by instillation in mice
  81. Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice
  82. Genotoxic and inflammatory effects of nanofibrillated cellulose in murine lungs
  83. A common variant within the HNF1B gene is associated with overall survival of multiple myeloma patients: results from the IMMEnSE consortium and meta-analysis
  84. Systematic review: genetic biomarkers associated with anti-TNF treatment response in inflammatory bowel diseases
  85. Multi-walled carbon nanotube physicochemical properties predict pulmonary inflammation and genotoxicity
  86. Genome-wide association study identifies multiple susceptibility loci for multiple myeloma
  87. No cytotoxicity or genotoxicity of graphene and graphene oxide in murine lung epithelial FE1 cells in vitro
  88. Fine-mapping markers of lung cancer susceptibility in a sub-region of chromosome 19q13.3 among Chinese
  89. Alcohol-related breast cancer in postmenopausal women – effect of CYP19A1, PPARG and PPARGC1A polymorphisms on female sex-hormone levels and interaction with alcohol consumption and NSAID usage in a nested case-control study and a randomised controlled...
  90. Effect of a long-term high-protein diet on survival, obesity development, and gut microbiota in mice
  91. Occupational exposure levels of bioaerosol components are associated with serum levels of the acute phase protein Serum Amyloid A in greenhouse workers
  92. Polymorphisms in the Toll-Like Receptor and the IL-23/IL-17 Pathways Were Associated with Susceptibility to Inflammatory Bowel Disease in a Danish Cohort
  93. Nano-risk Science: application of toxicogenomics in an adverse outcome pathway framework for risk assessment of multi-walled carbon nanotubes
  94. Carbon black nanoparticles induce biphasic gene expression changes associated with inflammatory responses in the lungs of C57BL/6 mice following a single intratracheal instillation
  95. Epoxy composite dusts with and without carbon nanotubes cause similar pulmonary responses, but differences in liver histology in mice following pulmonary deposition
  96. Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials
  97. Association and interaction of NFKB1 rs28362491 insertion/deletion ATTG polymorphism and PPP1R13L and CD3EAP related to lung cancer risk in a Chinese population
  98. Acute and subacute pulmonary toxicity and mortality in mice after intratracheal instillation of ZnO nanoparticles in three laboratories
  99. Genetic Variations in Pattern Recognition Receptor Loci Are Associated with Anti-TNF Response in Patients with Rheumatoid Arthritis
  100. Synergy of two human endogenous retroviruses in multiple myeloma
  101. Visualization of Nanofibrillar Cellulose in Biological Tissues Using a Biotinylated Carbohydrate Binding Module of β-1,4-Glycanase
  102. NFKB1 common variants and PPP1R13L and CD3EAP in relation to lung cancer risk in a Chinese population
  103. A perspective on the developmental toxicity of inhaled nanoparticles
  104. Polymorphisms in ATP-binding cassette transporter genes and interaction with diet and life style factors in relation to colorectal cancer in a Danish prospective case-cohort study
  105. Type 2 diabetes-related variants influence the risk of developing multiple myeloma: results from the IMMEnSE consortium
  106. Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma
  107. Intratracheally instilled titanium dioxide nanoparticles translocate to heart and liver and activate complement cascade in the heart of C57BL/6 mice
  108. New basal cell carcinoma susceptibility loci
  109. MWCNTs of different physicochemical properties cause similar inflammatory responses, but differences in transcriptional and histological markers of fibrosis in mouse lungs
  110. High ABCC2 and Low ABCG2 Gene Expression Are Early Events in the Colorectal Adenoma-Carcinoma Sequence
  111. DNA strand breaks, acute phase response and inflammation following pulmonary exposure by instillation to the diesel exhaust particle NIST1650b in mice
  112. Reduced ex vivo stimulated IL-6 response in infants randomized to fish oil from 9 to 18 months, especially among PPARG2 and COX2 wild types
  113. Changes in cholesterol homeostasis and acute phase response link pulmonary exposure to multi-walled carbon nanotubes to risk of cardiovascular disease
  114. Polymorphisms in NFKB1 and TLR4 and Interaction with Dietary and Life Style Factors in Relation to Colorectal Cancer in a Danish Prospective Case-Cohort Study
  115. In vitro screening of inhibition of PPAR-γ activity as a first step in identification of potential breast carcinogens
  116. Time-Dependent Subcellular Distribution and Effects of Carbon Nanotubes in Lungs of Mice
  117. Lessons learned from research on air pollution and other particles in the toxicology of nanomaterials and vice versa
  118. No Association between HMOX1 and Risk of Colorectal Cancer and No Interaction with Diet and Lifestyle Factors in a Prospective Danish Case-Cohort Study
  119. Novel understanding of ABC transporters ABCB1/MDR/P-glycoprotein, ABCC2/MRP2, and ABCG2/BCRP in colorectal pathophysiology
  120. Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response
  121. Interactions between meat intake and genetic variation in relation to colorectal cancer
  122. Characterization of genotoxic response to 15 multiwalled carbon nanotubes with variable physicochemical properties including surface functionalizations in the FE1-Muta(TM) mouse lung epithelial cell line
  123. Common variants in CYP2R1 and GC genes are both determinants of serum 25-hydroxyvitamin D concentrations after UVB irradiation and after consumption of vitamin D3–fortified bread and milk during winter in Denmark
  124. A unified framework for nanosafety is needed
  125. Intestinal PTGS2 mRNA Levels, PTGS2 Gene Polymorphisms, and Colorectal Carcinogenesis
  126. Risk of multiple myeloma is associated with polymorphisms within telomerase genes and telomere length
  127. FADS single-nucleotide polymorphisms are associated with behavioral outcomes in children, and the effect varies between sexes and is dependent on PPAR genotype
  128. DNA damage following pulmonary exposure by instillation to low doses of carbon black (Printex 90) nanoparticles in mice
  129. Polymorphisms in the heparanase gene in multiple myeloma association with bone morbidity and survival
  130. Imputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33
  131. Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort
  132. Anti-TNF Treatment Response in Rheumatoid Arthritis Patients Is Associated with Genetic Variation in the NLRP3-Inflammasome
  133. Real-life use of vitamin D3-fortified bread and milk during a winter season: the effects of CYP2R1 and GC genes on 25-hydroxyvitamin D concentrations in Danish families, the VitmaD study
  134. Particle-induced pulmonary acute phase response may be the causal link between particle inhalation and cardiovascular disease
  135. Systematic review: interactions between aspirin, and other nonsteroidal anti-inflammatory drugs, and polymorphisms in relation to colorectal cancer
  136. Genetic variants in theP2RX7gene are associated with risk of multiple myeloma
  137. Associations between functional polymorphisms in the NFκB signaling pathway and response to anti-TNF treatment in Danish patients with inflammatory bowel disease
  138. Effects on metabolic markers are modified by PPARG2 and COX2 polymorphisms in infants randomized to fish oil
  139. Common Variants in CYP2R1 and GC Genes Predict Vitamin D Concentrations in Healthy Danish Children and Adults
  140. Genetic Variants and Multiple Myeloma Risk: IMMEnSE Validation of the Best Reported Associations--An Extensive Replication of the Associations from the Candidate Gene Era
  141. FIB-SEM imaging of carbon nanotubes in mouse lung tissue
  142. Germline sequence variants in TGM3 and RGS22 confer risk of basal cell carcinoma
  143. ITS-NANO - Prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy
  144. HapMap-based study identifies risk sub-region on chromosome 19q13.3 in relation to lung cancer among Chinese
  145. Transcriptomic Analysis Reveals Novel Mechanistic Insight into Murine Biological Responses to Multi-Walled Carbon Nanotubes in Lungs and Cultured Lung Epithelial Cells
  146. In utero exposure to nanosized carbon black (Printex90) does not induce tandem repeat mutations in female murine germ cells
  147. Effects of lung exposure to carbon nanotubes on female fertility and pregnancy. A study in mice
  148. Interactions between Diet, Lifestyle and IL10, IL1B, and PTGS2/COX-2 Gene Polymorphisms in Relation to Risk of Colorectal Cancer in a Prospective Danish Case-Cohort Study
  149. Validation of freezing tissues and cells for analysis of DNA strand break levels by comet assay
  150. Carbon Black Nanoparticle Intratracheal Instillation Does Not Alter Cardiac Gene Expression
  151. Bioaccumulation and ecotoxicity of carbon nanotubes
  152. Association between Polymorphisms in Glutathione Peroxidase and Selenoprotein P Genes, Glutathione Peroxidase Activity, HRT Use and Breast Cancer Risk
  153. Variation in the Sodium-Dependent Vitamin C Transporter 2 Gene Is Associated with Risk of Acute Coronary Syndrome among Women
  154. Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies
  155. Particle-Induced Pulmonary Acute Phase Response Correlates with Neutrophil Influx Linking Inhaled Particles and Cardiovascular Risk
  156. Polymorphisms in genes related to inflammation, NSAID use, and the risk of prostate cancer among Danish men
  157. Aberrant DNA methylation of miR-219 promoter in long-term night shiftworkers
  158. Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation
  159. High-Quality and -Quantity DNA Extraction from Frozen Archival Blood Clots for Genotyping of Single-Nucleotide Polymorphisms
  160. Commentary
  161. Interaction between Obesity and the NFKB1 - 94ins/delATTG Promoter Polymorphism in Relation to Incident Acute Coronary Syndrome: A Follow Up Study in Three Independent Cohorts
  162. FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants
  163. Daily sperm production: Application in studies of prenatal exposure to nanoparticles in mice
  164. Gene expression profiling to identify potentially relevant disease outcomes and support human health risk assessment for carbon black nanoparticle exposure
  165. Systematic review: diet-gene interactions and the risk of colorectal cancer
  166. Methylation alterations at imprinted genes detected among long-term shiftworkers
  167. Alcohol dehydrogenase and aldehyde dehydrogenase gene polymorphisms, alcohol intake and the risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study
  168. Impact of polymorphic variation at 7p15.3, 3p22.1 and 2p23.3 loci on risk of multiple myeloma
  169. No evidence of association between the synonymous polymorphisms in XRCC1 and ERCC2 and breast cancer susceptibility among nonsmoking Chinese
  170. Single Nucleotide Polymorphisms in IL1B and the Risk of Acute Coronary Syndrome: A Danish Case-Cohort Study
  171. Carbon black nanoparticle intratracheal installation results in large and sustained changes in the expression of miR-135b in mouse lung
  172. Role of CYP1A2 polymorphisms on lung cancer risk in a prospective study
  173. Exposure of pregnant mice to carbon black by intratracheal instillation: Toxicogenomic effects in dams and offspring
  174. A specific diplotype defined by PPP1R13L rs1970764, CD3EAP rs967591 and ERCC1 rs11615 and lung cancer risk in a Chinese population
  175. Interaction between interleukin-10 (IL-10) polymorphisms and dietary fibre in relation to risk of colorectal cancer in a Danish case-cohort study
  176. A functional polymorphism in the promoter region of the IL1B gene is associated with risk of multiple myeloma
  177. A Risk Model for Lung Cancer Incidence
  178. Hepatic and Pulmonary Toxicogenomic Profiles in Mice Intratracheally Instilled With Carbon Black Nanoparticles Reveal Pulmonary Inflammation, Acute Phase Response, and Alterations in Lipid Homeostasis
  179. ABCC2 transporter gene polymorphisms, diet and risk of colorectal cancer: a Danish prospective cohort study
  180. Diet and risk of inflammatory bowel disease
  181. Hapmap-based evaluation of ERCC2, PPP1R13L, and ERCC1 and lung cancer risk in a Chinese population
  182. PPARgamma-PGC-1alpha activity is determinant of alcohol related breast cancer
  183. Vascular endothelial growth factor (VEGF) gene polymorphisms may influence the efficacy of thalidomide in multiple myeloma
  184. Cytotoxicity, oxidative stress and expression of adhesion molecules in human umbilical vein endothelial cells exposed to dust from paints with or without nanoparticles
  185. Nanotitanium dioxide toxicity in mouse lung is reduced in sanding dust from paint
  186. NanoTIO2 (UV-Titan) does not induce ESTR mutations in the germline of prenatally exposed female mice
  187. Colorectal cancer in patients with inflammatory bowel disease: Can we predict risk?
  188. Carbon black nanoparticle instillation induces sustained inflammation and genotoxicity in mouse lung and liver
  189. Association between 8-oxo-7,8-dihydroguanine excretion and risk of lung cancer in a prospective study
  190. Maternal inhalation of surface-coated nanosized titanium dioxide (UV-Titan) in C57BL/6 mice: effects in prenatally exposed offspring on hepatic DNA damage and gene expression
  191. Genetic variations in multiple myeloma I: effect on risk of multiple myeloma
  192. Genetic variations in multiple myeloma II: association with effect of treatment
  193. Epigenetic Impact of Long-Term Shiftwork: Pilot Evidence From Circadian Genes and Whole-Genome Methylation Analysis
  194. The NFKB1 ATTG ins/del polymorphism and risk of coronary heart disease in three independent populations
  195. Inflammatory and genotoxic effects of sanding dust generated from nanoparticle-containing paints and lacquers
  196. Assessment of heterogeneity between European Populations: a Baltic and Danish replication case-control study of SNPs from a recent European ulcerative colitis genome wide association study
  197. Subacute oral toxicity investigation of nanoparticulate and ionic silver in rats
  198. A germline variant in the TP53 polyadenylation signal confers cancer susceptibility
  199. The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer
  200. HapMap-based study of a region encompassing ERCC1 and ERCC2 related to lung cancer susceptibility in a Chinese population
  201. Effects of a 17q21 chromosome gene variant, tobacco smoke and furred pets on infant wheeze
  202. Prenatal Exposure to Carbon Black (Printex 90): Effects on Sexual Development and Neurofunction
  203. Single-nucleotide polymorphisms (5p15.33, 15q25.1, 6p22.1, 6q27 and 7p15.3) and lung cancer survival in the European Prospective Investigation into Cancer and Nutrition (EPIC)
  204. Genome-wide association study identifies new prostate cancer susceptibility loci
  205. Germline mutation rates in mice following in utero exposure to diesel exhaust particles by maternal inhalation
  206. Pulmonary exposure to carbon black by inhalation or instillation in pregnant mice: Effects on liver DNA strand breaks in dams and offspring
  207. Inflammatory and genotoxic effects of nanoparticles designed for inclusion in paints and lacquers
  208. Combinations of Polymorphisms in Genes Involved in the 5-Fluorouracil Metabolism Pathway Are Associated with Gastrointestinal Toxicity in Chemotherapy-Treated Colorectal Cancer Patients
  209. Cyclooxygenase-2 (COX-2) polymorphisms and risk of inflammatory bowel disease in a Scottish and Danish case–control study
  210. Heme oxygenase-1 polymorphism is not associated with riskof colorectal cancer
  211. Single nucleotide polymorphisms in the promoter region of the IL1B gene influence outcome in multiple myeloma patients treated with high-dose chemotherapy independently of relapse treatment with thalidomide and bortezomib
  212. Genetic variation in the hTAS2R38taste receptor and brassica vegetable intake
  213. Comprehensive Analysis of Hormone and Genetic Variation in 36 Genes Related to Steroid Hormone Metabolism in Pre- and Postmenopausal Women from the Breast and Prostate Cancer Cohort Consortium (BPC3)
  214. Pulmonary response to surface‐coated nanotitanium dioxide particles includes induction of acute phase response genes, inflammatory cascades, and changes in microRNAs: A toxicogenomic study
  215. Polymorphisms in NF-κB, PXR, LXR, PPARγ and risk of inflammatory bowel disease
  216. Mutagenicity of Carbon Nanomaterials
  217. Modest effect on plaque progression and vasodilatory function in atherosclerosis-prone mice exposed to nanosized TiO2
  218. Distribution of silver in rats following 28 days of repeated oral exposure to silver nanoparticles or silver acetate
  219. Correction: Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice
  220. 8-Oxoguanine DNA-glycosylase repair activity and expression: A comparison between cryopreserved isolated lymphocytes and EBV-derived lymphoblastoid cell lines
  221. p53 and PPP1R13L (alias iASPP or RAI) form a feedback loop to regulate genotoxic stress responses
  222. An Experimental Protocol for Maternal Pulmonary Exposure in Developmental Toxicology
  223. The importance of a sub-region on chromosome 19q13.3 for prognosis of multiple myeloma patients after high-dose treatment and stem cell support: a linkage disequilibrium mapping in RAI and CD3EAP
  224. Mutation spectrum in FE1-MUTATMMouse lung epithelial cells exposed to nanoparticulate carbon black
  225. The INSIG2 rs7566605 polymorphism is not associated with body mass index and breast cancer risk
  226. Physical-chemical and microbiological characterization, and mutagenic activity of airborne PM sampled in a biomass-fueled electrical production facility
  227. Polymorphisms in NFkB, PXR, LXR and risk of colorectal cancer in a prospective study of Danes
  228. Interaction between ADH1C Arg272Gln and alcohol intake in relation to breast cancer risk suggests that ethanol is the causal factor in alcohol related breast cancer
  229. Improved survival of multiple myeloma patients with late relapse after high-dose treatment and stem cell support, a population-based study of 348 patients in Denmark in 1994-2004*
  230. No influence of the polymorphisms CYP2C19 and CYP2D6 on the efficacy of cyclophosphamide, thalidomide, and bortezomib in patients with Multiple Myeloma
  231. The polymorphism rs3024505 proximal to IL-10 is associated with risk of ulcerative colitis and Crohns disease in a Danish case-control study
  232. Alcohol drinking habits, alcohol dehydrogenase genotypes and risk of acute coronary syndrome
  233. Lifestyle, Environmental, and Genetic Predictors of Bulky DNA Adducts in a Study Population Nested within a Prospective Danish Cohort
  234. Associations between COX-2 polymorphisms, blood cholesterol and risk of acute coronary syndrome
  235. Effects of prenatal exposure to surface-coated nanosized titanium dioxide (UV-Titan). A study in mice
  236. Polymorphisms in fatty acid metabolism-related genes are associated with colorectal cancer risk
  237. Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study
  238. Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation
  239. Variation in the measurement of DNA damage by comet assay measured by the ECVAG  inter-laboratory validation trial
  240. Polymorphisms in inflammation genes, tobacco smoke and furred pets and wheeze in children
  241. Enforced expression ofPPP1R13Lincreases tumorigenesis and invasion through p53-dependent and p53-independent mechanisms
  242. A polymorphism in NFKB1 is associated with improved effect of interferon-  maintenance treatment of patients with multiple myeloma after high-dose treatment with stem cell support
  243. Diesel Exhaust Particles: Effects on Neurofunction in Female Mice
  244. Expression of prostasin and its inhibitors during colorectal cancer carcinogenesis
  245. PPARγ Pro12Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes
  246. Protracted elimination of gold nanoparticles from mouse liver
  247. The Polymorphism of DNA Repair Gene ERCC2/XPD Arg156Arg and Susceptibility to Breast Cancer in a Chinese Population
  248. MTHFR polymorphisms and 5-FU-based adjuvant chemotherapy in colorectal cancer
  249. The T111I variant in the endothelial lipase gene and risk of coronary heart disease in three independent populations
  250. GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer
  251. HapMap-based study of the DNA repair gene ERCC2 and lung cancer susceptibility in a Chinese population
  252. Haplotype frequencies in a sub-region of chromosome 19q13.3, related to risk and prognosis of cancer, differ dramatically between ethnic groups
  253. Stratification for smoking in case-cohort studies of genetic polymorphisms and lung cancer
  254. Association of a single nucleotide polymorphic variation in the human chromosome 19q13.3 with drug responses in the NCI60 cell lines
  255. Genetic variation in genes of the fatty acid synthesis pathway and breast cancer risk
  256. The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study
  257. S447X variant of the lipoprotein lipase gene, lipids, and risk of coronary heart disease in 3 prospective cohort studies
  258. Aspirin and other non-steroidal anti-inflammatory drugs and risk of colorectal cancer: A Danish cohort study
  259. Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice
  260. Lack of acute phase response in the livers of mice exposed to diesel exhaust particles or carbon black by inhalation
  261. Association of DNA repair gene XRCC1 and lung cancer susceptibility among nonsmoking Chinese women
  262. The polymorphism IL-1β T-31C is associated with a longer overall survival in patients with multiple myeloma undergoing auto-SCT
  263. Genotoxicity, cytotoxicity, and reactive oxygen species induced by single‐walled carbon nanotubes and C60fullerenes in the FE1‐Muta™Mouse lung epithelial cells
  264. Linkage disequilibrium mapping of a breast cancer susceptibility locus near RAI/PPP1R13L/iASPP
  265. Haplotypes of nine single nucleotide polymorphisms on chromosome 19q13.2-3 associated with susceptibility of lung cancer in a Chinese population
  266. Diesel exhaust particles are mutagenic in FE1-Muta™Mouse lung epithelial cells
  267. Nonsteroidal anti-inflammatory drug use and breast cancer risk: a Danish cohort study
  268. Polymorphisms in genes involved in the inflammatory response and interaction with NSAID use or smoking in relation to lung cancer risk in a prospective study
  269. OGG1 expression and OGG1 Ser326Cys polymorphism and risk of lung cancer in a prospective study
  270. K-rasmutations in sinonasal cancers in relation to wood dust exposure
  271. A haplotype of polymorphisms in ASE-1, RAI and ERCC1and the effects of tobacco smoking and alcohol consumption on risk of colorectal cancer: a danish prospective case-cohort study
  272. Sucrose, glucose and fructose have similar genotoxicity in the rat colon and affect the metabolome
  273. Polymorphisms in nucleotide excision repair genes, smoking and intake of fruit and vegetables in relation to lung cancer
  274. Effects of prenatal exposure to diesel exhaust particles on postnatal development, behavior, genotoxicity and inflammation in mice
  275. DNA damage in rats after a single oral exposure to diesel exhaust particles
  276. Dietary exposure to diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase 1 deficient mice
  277. Prospective study of interaction between alcohol, NSAID use and polymorphisms in genes involved in the inflammatory response in relation to risk of colorectal cancer
  278. Genotoxicity, inflammation and physico-chemical properties of fine particle samples from an incineration energy plant and urban air
  279. Peroxisome Profilerator-Activated Receptor-gamma2 Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes
  280. Inflammatory response and genotoxicity of seven wood dusts in the human epithelial cell line A549
  281. Expression of the RAI gene is conducive to apoptosis: Studies of induction and interference
  282. XPA A23G, XPC Lys939Gln, XPD Lys751Gln and XPD Asp312Asn polymorphisms, interactions with smoking, alcohol and dietary factors, and risk of colorectal cancer
  283. The DNA repair gene XRCC1 and genetic susceptibility of lung cancer in a northeastern Chinese population
  284. A haplotype encompassing the variant allele of DNA repair gene polymorphism ERCC2/XPD Lys751Gln but not the variant allele of Asp312Asn is associated with risk of lung cancer in a northeastern Chinese population
  285. Polymorphisms in COX-2, NSAID use and risk of basal cell carcinoma in a prospective study of Danes
  286. GPX1 Pro198Leu polymorphism, interactions with smoking and alcohol consumption, and risk for lung cancer
  287. Gene-environment interactions between smoking and a haplotype of RAI, ASE-1 and ERCC1 polymorphisms among women in relation to risk of lung cancer in a population-based study
  288. Repeated inhalations of diesel exhaust particles and oxidatively damaged DNA in young oxoguanine DNA glycosylase (OGG1) deficient mice
  289. Kupffer cells are central in the removal of nanoparticles from the organism
  290. Increased mutant frequency by carbon black, but not quartz, in thelacZ andcII transgenes of muta™mouse lung epithelial cells
  291. Polymorphisms in the genes ERCC2, XRCC3 and CD3EAP influence treatment outcome in multiple myeloma patients undergoing autologous bone marrow transplantation
  292. Increased mRNA expression levels of ERCC1, OGG1 and RAIin colorectal adenomas and carcinomas
  293. Polymorphism of the DNA repair gene ERCC2 Lys751Gln and risk of lung cancer in a northeastern Chinese population
  294. Peroxisome profilerator-activated receptor 2 Pro12Ala, interaction with alcohol intake and NSAID use, in relation to risk of breast cancer in a prospective study of Danes
  295. The ratio of Matriptase/HAI-1mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals
  296. Effects of polymorphisms in ERCC1, ASE-1 and RAIon the risk of colorectal carcinomas and adenomas: a case control study
  297. Bulky DNA adducts as risk indicator of lung cancer in a Danish case-cohort study
  298. Polymorphisms of the XRCC1, XRCC3 and XPDgenes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study
  299. Biological effects of fruit and vegetables
  300. Prospective study of 8-oxo-7,8-dihydro-2'-deoxyguanosine excretion and the risk of lung cancer
  301. Bulky DNA adducts as risk indicators of lung cancer in a Danish case-cohort study
  302. Lack of association between DNA repair gene ERCC1 polymorphism and risk of lung cancer in a Chinese population
  303. Interactions between theOGG1Ser326Cys polymorphism and intake of fruit and vegetables in relation to lung cancer
  304. ERCC1, XPD and RAI mRNA levels in lymphocytes are not associated with lung cancer risk in a prospective study of Danes
  305. GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer
  306. Associations between GPX1 Pro198Leu polymorphism, erythrocyte GPX activity, alcohol consumption and breast cancer risk in a prospective cohort study
  307. Polymorphisms of DNA Repair Genes: ERCC1 G19007A and ERCC2/XPD C22541A in a Northeastern Chinese Population
  308. Polymorphisms in RAI and in genes of nucleotide and base excision repair are not associated with risk of testicular cancer
  309. The DNA repair gene ERCC2/XPD polymorphism Arg 156Arg (A22541C) and risk of lung cancer in a Chinese population
  310. Tumor necrosis factor is not required for particle-induced genotoxicity and pulmonary inflammation
  311. Combinations of polymorphisms in XPD, XPC and XPA in relation to risk of lung cancer
  312. SNP genotyping using microsphere-linked PNA and flow cytometric detection
  313. Effect of polymorphisms in XPD, RAI, ASE-1 and ERCC1 on the risk of basal cell carcinoma among Caucasians after age 50
  314. No Association Between Base Excision Repair Gene Polymorphisms and Risk of Lung Cancer
  315. Tumor necrosis factor is not required for particle-induced genotoxicity and pulmonary inflammation
  316. Sucrose and IQ induced mutations in rat colon by independent mechanism
  317. XRCC3 polymorphisms and risk of lung cancer
  318. DNA damage in lung after oral exposure to diesel exhaust particles in Big Blue® rats
  319. Effects of sucrose and cornstarch on 2-amino-3-methylimidazo[4,5-f]quinoline (IQ)-induced colon and liver carcinogenesis in F344 rats
  320. Cell-specific oxidative DNA damage induced by estrogen in rat testicular cells in vitro
  321. Short PNA molecular beacons for real-time PCR allelic discrimination of single nucleotide polymorphisms
  322. Two regions in chromosome 19q13.2-3 are associated with risk of lung cancer
  323. Dietary elevated sucrose modulation of diesel-induced genotoxicity in the colon and liver of Big Blue rats
  324. X-ray-induced Oxidative Stress: DNA Damage and Gene Expression of HO-1 , ERCC1 and OGG1 in Mouse Lung
  325. Effect of Increased Intake of Dietary Animal Fat and Fat Energy on Oxidative Damage, Mutation Frequency, DNA Adduct Level and DNA Repair in Rat Colon and Liver
  326. Oxidative DNA damage and defence gene expression in the mouse lung after short-term exposure to diesel exhaust particles by inhalation
  327. DNA adduct formation and oxidative stress in colon and liver of Big Blue(R) rats after dietary exposure to diesel particles
  328. Dietary low-dose sucrose modulation of IQ-induced genotoxicity in the colon and liver of Big Blue™ rats
  329. A specific haplotype of single nucleotide polymorphisms on chromosome 19q13.2-3 encompassing the gene RAI is indicative of post-menopausal breast cancer before age 55
  330. Inhalation of ozone induces DNA strand breaks and inflammation in mice
  331. DNA repair capacity: inconsistency between effect of over-expression of five NER genes and the correlation to mRNA levels in primary lymphocytes
  332. A strong genotoxic effect in mouse skin of a single painting of coal tar in hairless mice and in Muta™Mouse
  333. Low DNA repair is a risk factor in skin carcinogenesis: a study of basal cell carcinoma in psoriasis patients
  334. NusA Is Required for Ribosomal Antitermination and for Modulation of the Transcription Elongation Rate of both Antiterminated RNA and mRNA
  335. Effects of the Antiterminator BoxA on Transcription Elongation Kinetics and ppGpp Inhibition of Transcription Elongation in Escherichia coli
  336. The rates of macromolecular chain elongation modulate the initiation frequencies for transcription and translation inEscherichia coli