All Stories

  1. Genomic Analysis of Carbapenemase-Producing Extensively Drug-Resistant Klebsiella pneumoniae Isolates Reveals the Horizontal Spread of p18-43_01 Plasmid Encoding blaNDM-1 in South Africa

    Article • Microorganisms, January 2020, MDPI AG

    Dr Timothy Craig Hardcastle, Dr Mushal Allam

  2. Correlation of procalcitonin to positive blood culture results in a sample of South African trauma ICU patients between 2016 and 2017

    Article • European Journal of Trauma and Emergency Surgery, January 2020, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  3. South African Paediatric Surgical Outcomes Study: a 14-day prospective, observational cohort study of paediatric surgical patients

    Article • British Journal of Anaesthesia, February 2019, Elsevier

    Dr Timothy Craig Hardcastle, Dr Heidi Michelle Meyer

  4. 2018 WSES/SIS-E consensus conference: recommendations for the management of skin and soft-tissue infections

    Article • World Journal of Emergency Surgery, December 2018, Springer Science + Business Media

    Dr Timothy Craig Hardcastle, Dr Salomone Di Saverio

  5. The ASOS Surgical Risk Calculator: development and validation of a tool for identifying African surgical patients at risk of severe postoperative complications

    Article • British Journal of Anaesthesia, December 2018, Elsevier

    Dr Timothy Craig Hardcastle, Prof. Dr. Mahmoud ElFiky

  6. Knowledge, awareness, and attitude towards infection prevention and management among surgeons: identifying the surgeon champion

    Article • World Journal of Emergency Surgery, August 2018, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  7. Unplanned extubations in a level one trauma ICU

    Article • Southern African Journal of Anaesthesia and Analgesia, July 2018, Taylor & Francis

    Dr Timothy Craig Hardcastle

  8. Left pulmonary artery bullet embolism following a penetrating cardiac gunshot injury

    Article • African Journal of Emergency Medicine, July 2018, Elsevier

    Dr Timothy Craig Hardcastle

  9. Pneumomediastinum and pneumopericardium following blunt thoracic trauma: much ado about nothing?

    Article • European Journal of Trauma, April 2018, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  10. Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study

    Article • The Lancet, April 2018, Elsevier

    Prof. Dr. Mahmoud ElFiky, Dr Timothy Craig Hardcastle

  11. Burden, Characteristics and Process of Care Among the Pediatric and Adult Trauma Patients in Botswana’s Main Hospitals

    Article • World Journal of Surgery, February 2018, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  12. Raising concerns about the Sepsis-3 definitions

    Article • World Journal of Emergency Surgery, January 2018, Springer Science + Business Media

    Dr Timothy Craig Hardcastle, Dr Salomone Di Saverio

  13. Five year review of open radical nephrectomies at a regional hospital in South Africa: room for improvement

    Article • South African Journal of Surgery, January 2018, Academy of Science of South Africa

    Dr Timothy Craig Hardcastle

  14. Studies on the epidemiology of trauma: The first step in systems planning and system evaluation

    Article • Journal of Emergencies Trauma and Shock, January 2018, Medknow

    Dr Timothy Craig Hardcastle

  15. Regarding: Management of esophageal injuries secondary to trauma. Injury, 2017, 48: 1735–1742

    Article • Injury, December 2017, Elsevier

    Dr Timothy Craig Hardcastle

  16. Preventative measures taken against hypothermia in selected Durban hospitals’ emergency centres and operating theatres

    Article • African Journal of Emergency Medicine, December 2017, Elsevier

    Dr Timothy Craig Hardcastle

  17. Evaluation of Resources Necessary for Provision of Trauma Care in Botswana: An Initiative for a Local System

    Article • World Journal of Surgery, November 2017, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  18. Response to Letter to the Editor, Regarding Hardcastle TC, Muckart DJJ, Maier RV. Ventilation in Trauma Patients: The First 24 h is Different! World Journal of Surgery 2017;41(5):1153–1158

    Article • World Journal of Surgery, November 2017, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  19. Outcomes 30 days after ICU admission: the 30DOS study

    Article • Southern African Journal of Anaesthesia and Analgesia, November 2017, Taylor & Francis

    Dr Timothy Craig Hardcastle

  20. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

    Article • Surgical Infections, November 2017, Mary Ann Liebert Inc

    Dr Timothy Craig Hardcastle, Prof. Majdi Al-Hasan, MD Massimo Girardis, Francesco Di Marzo, Dr Salomone Di Saverio

  21. Regarding: Systematic review of rectal injury management, Injury 48: 1133–1138]

    Article • Injury, October 2017, Elsevier

    Dr Timothy Craig Hardcastle

  22. Erratum to: The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections

    Article • World Journal of Emergency Surgery, August 2017, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  23. The Global Alliance for Infections in Surgery: defining a model for antimicrobial stewardship—results from an international cross-sectional survey

    Article • World Journal of Emergency Surgery, August 2017, Springer Science + Business Media

    Prof. Majdi Al-Hasan, Dr Timothy Craig Hardcastle, Francesco Di Marzo, Andras Vereczkei

  24. Non-operative management for penetrating splenic trauma: how far can we go to save splenic function?

    Article • World Journal of Emergency Surgery, July 2017, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  25. The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections

    Article • World Journal of Emergency Surgery, July 2017, Springer Science + Business Media

    Luca Ansaloni, Dr Timothy Craig Hardcastle

  26. Introductory Overview: IATSIC Symposium, WJS

    Article • World Journal of Surgery, March 2017, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  27. Cervical collars and immobilisation: A South African best practice recommendation

    Article • African Journal of Emergency Medicine, March 2017, Elsevier

    Dr Timothy Craig Hardcastle

  28. Organised trauma systems and designated trauma centres for improving outcomes in injured patients

    Article • Cochrane Database of Systematic Reviews, January 2017, Wiley

    Dr Timothy Craig Hardcastle

  29. Hepatic dysfunction: A common occurrence in severely injured patients

    Article • Injury, January 2017, Elsevier

    Dr Timothy Craig Hardcastle

  30. Neurological findings in pediatric penetrating head injury at a university teaching hospital in Durban, South Africa: a 23-year retrospective study

    Article • Journal of Neurosurgery Pediatrics, November 2016, Journal of Neurosurgery Publishing Group (JNSPG)

    Dr Timothy C Hardcastle, Dr Kadhaya D Muballe, Dr Timothy Craig Hardcastle

  31. Lessons from the frontline: using experiences from conflict zones to improve trauma care and outcomes

    Article • International Health, November 2016, Oxford University Press (OUP)

    Dr Timothy Craig Hardcastle

  32. HIV, trauma and the emergency departments: The CDC opt-out approach should be adopted in South Africa

    Article • South African Journal of Bioethics and Law, October 2016, Health and Medical Publishing Group

    Dr Timothy Craig Hardcastle

  33. Collective Review of the Status of Rapid Sequence Intubation Drugs of Choice in Trauma in Low- and Middle-Income Settings (Prehospital, Emergency Department and Operating Room Setting)

    Article • World Journal of Surgery, September 2016, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  34. Ventilation in the Trauma Patient: A Practical Approach

    Article • September 2016, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  35. Ventilation in Trauma Patients: The First 24 h is Different!

    Article • World Journal of Surgery, May 2016, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  36. Surviving Sepsis in the Intensive Care Unit: The Challenge of Antimicrobial Resistance and the Trauma Patient

    Article • World Journal of Surgery, May 2016, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  37. National priorities for perioperative research in South Africa

    Article • South African Medical Journal, March 2016, Health and Medical Publishing Group

    Dr Timothy Craig Hardcastle

  38. Defining current facial fracture patterns in a quaternary institution following high-velocity blunt trauma

    Article • South African Journal of Radiology, March 2016, AOSIS Open Journals

    Dr Timothy Craig Hardcastle

  39. Endotracheal tube cuff pressures and tube position in critically injured patients on arrival at a referral centre: Avoidable harm?

    Article • African Journal of Emergency Medicine, March 2016, Elsevier

    Dr Timothy Craig Hardcastle

  40. An analysis of patients transported by a private helicopter emergency medical service in South Africa

    Article • South African Medical Journal, January 2016, Health and Medical Publishing Group

    Dr Timothy Craig Hardcastle

  41. Empirical antimicrobial therapy for probable v. directed therapy for possible ventilator-associated pneumonia in critically injured patients

    Article • South African Medical Journal, January 2016, Health and Medical Publishing Group

    Dr Timothy Craig Hardcastle

  42. A hospital based surveillance system to assess the burden of trauma in KwaZulu-Natal Province South Africa

    Article • Injury, January 2016, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  43. Early Management of Trauma

    Article • January 2016, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  44. Tertiary Survey and Avoiding Missed Injury

    Article • January 2016, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  45. Face and Neck Trauma

    Article • January 2016, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  46. Spinal stab injury with retained knife blades: 51 Consecutive patients managed at a regional referral unit

    Article • Injury, September 2015, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  47. What′s new in emergencies, trauma and shock? Extraperitoneal pelvic pressure packing: Placing this procedure in context

    Article • Journal of Emergencies Trauma and Shock, January 2015, Medknow

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  48. Selective non operative management of gunshot wounds to the abdomen: a collective review

    Article • International Emergency Nursing, January 2015, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  49. Blunt cardiac injury in critically ill trauma patients: A single centre experience

    Article • Injury, January 2015, Elsevier

    Dr Timothy Craig Hardcastle

  50. Complications relating to enteral and parenteral nutrition in trauma patients: a retrospective study at a level one trauma centre in South Africa

    Article • South African Journal of Clinical Nutrition, January 2015, Taylor & Francis

    Dr Timothy Craig Hardcastle

  51. Early enteral nutrition compared to outcome in critically ill trauma patients at a level one trauma centre

    Article • South African Journal of Clinical Nutrition, January 2015, Taylor & Francis

    Dr Timothy Craig Hardcastle

  52. Dysmagnesaemia and outcome in a trauma ICU

    Article • Southern African Journal of Critical Care, October 2014, Health and Medical Publishing Group

    Dr Timothy Craig Hardcastle

  53. Epidemiology and referral patterns of burns admitted to the Burns Centre at Inkosi Albert Luthuli Central Hospital, Durban

    Article • Burns, September 2014, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  54. Lactate clearance predicts outcome after major trauma

    Article • African Journal of Emergency Medicine, June 2014, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  55. Palliative care: Definition of euthanasia

    Article • South African Medical Journal, March 2014, Health and Medical Publishing Group

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  56. Penetrating thorax injury leads to mild systemic activation of neutrophils without inflammatory complications

    Article • Injury, March 2014, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  57. Vascular injuries following blunt polytrauma

    Article • European Journal of Trauma and Emergency Surgery, February 2014, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  58. The incidence and outcomes of acute kidney injury amongst patients admitted to a level I trauma unit

    Article • Injury, January 2014, Elsevier

    Dr Timothy Craig Hardcastle

  59. Temperature regulation in emergency, surgical and critical care

    Article • South African Medical Journal, August 2013, Health and Medical Publishing Group

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  60. External patient temperature control in emergency centres, trauma centres, intensive care units and operating theatres: A multi-society literature review

    Article • South African Medical Journal, August 2013, Health and Medical Publishing Group

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  61. Base deficit as an early marker of coagulopathy in trauma

    Article • South African Journal of Surgery, July 2013, Health and Medical Publishing Group

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  62. Trauma care in South Africa: From humble beginnings to an afrocentric outreach

    Article • International Emergency Nursing, April 2013, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  63. What′s new in emergencies, trauma and shock? Pellets, rubber bullets, and shotguns: Less lethal or not?

    Article • Journal of Emergencies Trauma and Shock, January 2013, Medknow

    Dr Timothy Craig Hardcastle

  64. Utilisation of a Level 1 Trauma Centre in KwaZulu-Natal: Appropriateness of Referral Determines Trauma Patient Access

    Article • World Journal of Surgery, December 2012, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  65. An Assessment of the Hospital Disease Burden and the Facilities for the In-hospital Care of Trauma in KwaZulu-Natal, South Africa

    Article • World Journal of Surgery, December 2012, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  66. The Prehospital Burden of Disease due to Trauma in KwaZulu-Natal: The Need for Afrocentric Trauma Systems

    Article • World Journal of Surgery, November 2012, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  67. South Africa: Where Have We Been?

    Article • August 2012, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  68. A Redundant Resource: A Pre-Planned Casualty Clearing Station for a FIFA 2010 Stadium in Durban

    Article • Prehospital and Disaster Medicine, May 2012, Cambridge University Press

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  69. Global Surgery Rotations for Residents

    Article • World Journal of Surgery, March 2012, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  70. Deaths at a Level 1 Trauma Unit: A clinical finding and post-mortem correlation study

    Article • Injury, January 2012, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  71. Reaching consensus on the physiotherapeutic management of patients following upper abdominal surgery: a pragmatic approach to interpret equivocal evidence

    Article • BMC Medical Informatics and Decision Making, January 2012, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  72. Indications for bullet removal: overview of the literature, and clinical practice guidelines for European trauma surgeons

    Article • European Journal of Trauma and Emergency Surgery, December 2011, Springer Science + Business Media

    Dr Timothy Craig Hardcastle

  73. Benign portal venous gas after blunt abdominal trauma

    Article • Injury Extra, November 2011, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  74. Trauma care in Africa: Triumphs and challenges

    Article • African Journal of Emergency Medicine, June 2011, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  75. Guideline for the assessment of trauma centres for South Africa

    Article • South African Medical Journal, March 2011, Health and Medical Publishing Group

    Dr Timothy Craig Hardcastle

  76. The 11P’s of an Afrocentric trauma system for South Africa – time for action!

    Article • South African Medical Journal, March 2011, Health and Medical Publishing Group

    Dr Timothy Craig Hardcastle

  77. A crushing experience: The spectrum and outcome of soft tissue injury and myonephropathic syndrome at an Urban South African University Hospital

    Article • African Journal of Emergency Medicine, March 2011, Elsevier

    Dr Timothy Craig Hardcastle

  78. The Moses Mabhida Medical Plan: medical care planning and execution at a FIFA2010 stadium; the Durban experience

    Article • Open Access Emergency Medicine, December 2010, Taylor & Francis

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle, Professor Gonasageran Naidoo

  79. Posttraumatic intrahepatic pseudoaneurysm in a child managed by coil angioembolization: a case report and literature review

    Article • Journal of Pediatric Surgery, June 2010, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  80. Medical electives in South Africa

    Article • South African Medical Journal, March 2010, Health and Medical Publishing Group

    Dr Timothy Craig Hardcastle

  81. Unusual Management of a Complex Pancreaticoduodenal Injury: Case Report and Brief Literature Review

    Article • Journal of Trauma and Acute Care Surgery, February 2010, Wolters Kluwer Health

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  82. RE: Helicopter Evacuation of Trauma Victims in Los Angeles: Does It Improve Survival?

    Article • World Journal of Surgery, January 2010, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  83. Blunt rupture of the right hemidiaphragm with herniation of the right colon and right lobe of the liver

    Article • Journal of Emergencies Trauma and Shock, January 2010, Medknow

    Dr Timothy Craig Hardcastle

  84. Imaging the oesophagus after penetrating cervical trauma using water-soluble contrast alone: simple, cost-effective and accurate

    Article • Emergency Medicine Journal, February 2009, BMJ

    Dr Timothy Craig Hardcastle

  85. Re: Pleural decompression and drainage during trauma reception and resuscitation [Injury 2008;39:9–20]

    Article • Injury, January 2009, Elsevier

    Dr Timothy Craig Hardcastle

  86. Letters to the Editor

    Article • Journal of Trauma and Acute Care Surgery, October 2008, Wolters Kluwer Health

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  87. Early onset fat embolism syndrome: Case report and literature review

    Article • Injury Extra, September 2008, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  88. Non-gravid uterine trauma

    Article • Injury Extra, August 2008, Elsevier

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  89. Letters to the Editor

    Article • Journal of Trauma and Acute Care Surgery, August 2008, Wolters Kluwer Health

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  90. Ethics of Surgical Training in Developing Countries

    Article • World Journal of Surgery, January 2008, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle

  91. Brachial Artery Injuries: A Seven-year Experience with a Prospective Database

    Article • European Journal of Trauma, October 2007, Springer Science + Business Media

    Dr Timothy C Hardcastle, Dr Timothy Craig Hardcastle