All Stories

  1. Perioperative Use of IgM-Enriched Immunoglobulins in Liver Transplantation Recipients at High Risk for Infections: A Preliminary Study
  2. Association between respiratory distress time and invasive mechanical ventilation in COVID-19 patients: A multicentre regional cohort study
  3. The Interplay between Antibiotics and the Host Immune Response in Sepsis: From Basic Mechanisms to Clinical Considerations: A Comprehensive Narrative Review
  4. Advances and Challenges in Sepsis Management: Modern Tools and Future Directions
  5. The Association of Procalcitonin and C-Reactive Protein with Bacterial Infections Acquired during Intensive Care Unit Stay in COVID-19 Critically Ill Patients
  6. Role of Selective Digestive Decontamination in the Prevention of Ventilator-Associated Pneumonia in COVID-19 Patients: A Pre-Post Observational Study
  7. Do All Critically Ill Patients with COVID-19 Disease Benefit from Adding Tocilizumab to Glucocorticoids? A Retrospective Cohort Study
  8. Ceftazidime/Avibactam in Ventilator-Associated Pneumonia Due to Difficult-to-Treat Non-Fermenter Gram-Negative Bacteria in COVID-19 Patients: A Case Series and Review of the Literature
  9. Patients Recovering from Severe COVID-19 Develop a Polyfunctional Antigen-Specific CD4+ T Cell Response
  10. Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis: an international cohort study
  11. Long-Term Impact of the COVID-19 Pandemic on In-Hospital Antibiotic Consumption and Antibiotic Resistance: A Time Series Analysis (2015–2021)
  12. Communication and visiting policies in Italian intensive care units during the first COVID-19 pandemic wave and lockdown: a nationwide survey
  13. Molecular and cellular immune features of aged patients with severe COVID-19 pneumonia
  14. Carriers of ADAMTS13 Rare Variants Are at High Risk of Life-Threatening COVID-19
  15. Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality
  16. Early awake proning in critical and severe COVID-19 patients undergoing noninvasive respiratory support: A retrospective multicenter cohort study
  17. Risk Factors for Pulmonary Air Leak and Clinical Prognosis in Patients With COVID-19 Related Acute Respiratory Failure: A Retrospective Matched Control Study
  18. Nasal pressure swings as the measure of inspiratory effort in spontaneously breathing patients with de novo acute respiratory failure
  19. Plasma Cytokine Atlas Reveals the Importance of TH2 Polarization and Interferons in Predicting COVID-19 Severity and Survival
  20. Editorial: Putting the Spotlight on the Role of Oxygen in Critically-Ill Patients: From Basic Mechanisms to Clinical Effects
  21. Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study
  22. Correction: Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia
  23. First and second waves among hospitalised patients with COVID-19 with severe pneumonia: a comparison of 28-day mortality over the 1-year pandemic in a tertiary university hospital in Italy
  24. The effect of non-invasive ventilation on intra-abdominal pressure
  25. Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients
  26. Metabolic reprograming shapes neutrophil functions in severe COVID‐19
  27. Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity
  28. Development of post-COVID-19 cardiovascular events: an analysis of clinical features and risk factors from a single hospital retrospective study
  29. Mapping the human genetic architecture of COVID-19: an update
  30. Acquisition of skills in critical emergency medicine: an experimental study on the SIAARTI Academy CREM experience
  31. Revisited Hyperoxia Pathophysiology in the Perioperative Setting: A Narrative Review
  32. Correction to: Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial
  33. Vertebral artery dissection in term pregnancy after cervical spine manipulation: a case report and review the literature
  34. Author Correction: Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
  35. Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia
  36. Inspiratory Effort and Lung Mechanics in Spontaneously Breathing Patients with Acute Respiratory Failure due to COVID-19: A Matched Control Study
  37. Synergistic Effect of Static Compliance and D-dimers to Predict Outcome of Patients with COVID-19-ARDS: A Prospective Multicenter Study
  38. Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity
  39. A pandemic recap: lessons we have learned
  40. Herpes Simplex Virus Re-Activation in Patients with SARS-CoV-2 Pneumonia: A Prospective, Observational Study
  41. Exogenous pulmonary surfactant in COVID-19 ARDS. The similarities to neonatal RDS suggest a new scenario for an ‘old’ strategy
  42. A five-component infection control bundle to permanently eliminate a carbapenem-resistant Acinetobacter baumannii spreading in an intensive care unit
  43. The impact of tocilizumab on respiratory support states transition and clinical outcomes in COVID-19 patients. A Markov model multi-state study
  44. Rationale for Polyclonal Intravenous Immunoglobulin Adjunctive Therapy in COVID-19 Patients: Report of a Structured Multidisciplinary Consensus
  45. Better prognosis in females with severe COVID-19 pneumonia: possible role of inflammation as potential mediator
  46. Hospital-Acquired Infections in Critically Ill Patients With COVID-19
  47. Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
  48. Mapping the human genetic architecture of COVID-19
  49. One‐year persistence of neutralizing anti‐SARS‐CoV‐2 antibodies in dialysis patients recovered from COVID‐19
  50. Incidence, risk factors and outcome of acute kidney injury (AKI) in patients with COVID-19
  51. C9orf72 Intermediate Repeats Confer Genetic Risk for Severe COVID-19 Pneumonia Independently of Age
  52. Monocyte Distribution Width (MDW) as novel inflammatory marker with prognostic significance in COVID-19 patients
  53. Acid base disorders in patients with COVID-19
  54. Good clinical practice for the use of vasopressor and inotropic drugs in critically ill patients: state-of-the-art and expert consensus
  55. The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
  56. SELP Asp603Asn and severe thrombosis in COVID-19 males: implication for anti P-selectin monoclonal antibodies treatment
  57. Mergers and acquisitions in emerging markets: What drives absorptive capacity in target firms?
  58. Identification and characterization of a SARS-CoV-2 specific CD8+ T cell response with immunodominant features
  59. Never Give Up: Lesson learned from a severe COVID-19 patient
  60. Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients
  61. An update on levosimendan in acute cardiac care: applications and recommendations for optimal efficacy and safety
  62. Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge
  63. The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males
  64. Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study
  65. Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males
  66. Development and validation of a prediction model for tocilizumab failure in hospitalized patients with SARS-CoV-2 infection
  67. Adjunctive Immunotherapy With Polyclonal Ig-M Enriched Immunoglobulins for Septic Shock: From Bench to Bedside. The Rationale for a Personalized Treatment Protocol
  68. Incidence and Prognosis of Ventilator-Associated Pneumonia in Critically Ill Patients with COVID-19: A Multicenter Study
  69. Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)
  70. Post-Mendelian genetic model in COVID-19
  71. Employing a systematic approach to biobanking and analyzing clinical and genetic data for advancing COVID-19 research
  72. Hypokalemia in Patients with COVID-19
  73. Cluster analysis identifies patients at risk of catheter-associated urinary tract infections in intensive care units: findings from the SPIN-UTI Network
  74. Genetic mechanisms of critical illness in Covid-19
  75. Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study
  76. Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males
  77. Clinical and molecular characterization of COVID-19 hospitalized patients
  78. Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia—Challenges, strengths, and opportunities in a global health emergency
  79. Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in males
  80. Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia
  81. Testicular pain as an unusual presentation of COVID-19: a brief review of SARS-CoV-2 and the testis
  82. Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy
  83. Best-practice IgM- and IgA-enriched immunoglobulin use in patients with sepsis
  84. Adjunctive therapy with vitamin c and thiamine in patients treated with steroids for refractory septic shock: A propensity matched before-after, case-control study
  85. COVID-19-associated vasculitis and thrombotic complications: from pathological findings to multidisciplinary discussion
  86. The predictive value of fruit juice in the esophagus-pleural fistula
  87. Two Fatal Cases of Acute Liver Failure Due to HSV-1 Infection in COVID-19 Patients Following Immunomodulatory Therapies
  88. Multi-centre, three arm, randomized controlled trial on the use of methylprednisolone and unfractionated heparin in critically ill ventilated patients with pneumonia from SARS-CoV-2 infection: A structured summary of a study protocol for a randomised c...
  89. Early Inspiratory Effort Assessment by Esophageal Manometry Predicts Noninvasive Ventilation Outcome in De Novo Respiratory Failure. A Pilot Study
  90. Expansion of plasmablasts and loss of memory B cells in peripheral blood from COVID‐19 patients with pneumonia
  91. Tocilizumab in patients with severe COVID-19: a retrospective cohort study
  92. Employing a Systematic Approach to Biobanking and Analyzing Clinical and Genetic Data for Advancing COVID-19 Research
  93. Guide-wire replacement of a mini-midline catheter with a central venous catheter: A retrospective study on 63 cases
  94. ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population
  95. Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia
  96. Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use
  97. Incidence, Risk Factors and Mortality Outcome in Patients with Acute Kidney Injury in COVID-19: A Single-Center Observational Study
  98. A case of splenic artery pseudoaneurysm rupture in a bulimic patient with gastric ulcer
  99. Reply to “Indications and timing for tracheostomy in patients with SARS CoV2‐related” by Ferri et al.
  100. Hypokalemia in Patients with COVID-19
  101. Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study
  102. Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia - challenges, strengths, and opportunities in a global health emergency
  103. Clinical and molecular characterization of COVID-19 hospitalized patients
  104. Increased Plasma Levels of Mitochondrial DNA and Normal Inflammasome Gene Expression in Monocytes Characterize Patients With Septic Shock Due to Multidrug Resistant Bacteria
  105. The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database
  106. Tracheostomy in the COVID-19 pandemic
  107. Ceftolozane/Tazobactam for Treatment of Severe ESBL-Producing Enterobacterales Infections: A Multicenter Nationwide Clinical Experience (CEFTABUSE II Study)
  108. Handling and Processing of Blood Specimens from Patients with COVID‐19 for Safe Studies on Cell Phenotype and Cytokine Storm
  109. SARS‐CoV‐2, the Virus that Causes COVID‐19: Cytometry and the New Challenge for Global Health
  110. Case report of a patient who survived after cardiac arrest and cardiogenic shock by anaphylactic reaction to gadolinium during magnetic resonance imaging
  111. Shorter Androgen Receptor PolyQ Alleles Protect Against Life-Threatening COVID-19 Disease in Males
  112. OUP accepted manuscript
  113. Surfactant replacement might help recovery of low-compliance lung in severe COVID-19 pneumonia
  114. Current gaps in sepsis immunology: new opportunities for translational research
  115. University of Modena Experience With Liver Grafts From Donation After Circulatory Death: What Really Matters in Organ Selection?
  116. Epidemiology of intra-abdominal infection and sepsis in critically ill patients: “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project
  117. Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project
  118. What’s new in oxygen therapy?
  119. Oxygen: a powerful drug to handle with care
  120. Cytoreductive surgery and HIPEC in a 14 years old patient with peritoneal recurrence of adenocarcinoma of the right colon
  121. Use of Levosimendan in Intensive Care Unit Settings
  122. Landiolol in patients with septic shock resident in an intensive care unit (LANDI-SEP): study protocol for a randomized controlled trial
  123. JLB: a new long-cannula venous catheter
  124. Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature
  125. Real-time monitoring of Pseudomonas aeruginosa biofilm formation on endotracheal tubes in vitro
  126. Experienced Use of Dexmedetomidine in the Intensive Care Unit: A Report of a Structured Consensus
  127. Prognostic Potential of the Panfungal Marker (1 → 3)-β-d-Glucan in Invasive Mycoses Patients
  128. Procalcitonin-guided antibiotic therapy: an expert consensus
  129. Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)
  130. Oxygen in the critically ill
  131. The prognostic importance of chronic end-stage diseases in geriatric patients admitted to 163 Italian ICUs
  132. Correction to: The Intensive Care Global Study on Severe Acute Respiratory Infection (IC-GLOSSARI): a multicenter, multinational, 14-day inception cohort study
  133. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway
  134. Common Practice and Guidelines for Sedation in Critically Ill Patients
  135. Randomized, multicenter trial of lateral Trendelenburg versus semirecumbent body position for the prevention of ventilator-associated pneumonia
  136. Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference
  137. Effects of short-term hyperoxia on erythropoietin levels and microcirculation in critically Ill patients: a prospective observational pilot study
  138. Injury-induced immunosuppression: are we finally on the right track?
  139. Oxygen Supplementation Among Patients in the Intensive Care Unit
  140. Mortality in Patients With Septic Shock by Multidrug Resistant Bacteria
  141. Impact of Pre-Analytical Time on the Recovery of Pathogens from Blood Cultures: Results from a Large Retrospective Survey
  142. The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDR/XDR Infections
  143. Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit
  144. Dexmedetomidine for agitated delirium in intensive care unit intubated patients
  145. Evaluation of serum (1 → 3)-β-d-glucan clinical performance: kinetic assessment, comparison with galactomannan and evaluation of confounding factors
  146. A one-year prospective study of refractory status epilepticus in Modena, Italy
  147. The Surviving Sepsis Campaign bundles and outcome: results from the International Multicentre Prevalence Study on Sepsis (the IMPreSS study)
  148. A challenging case of pregnancy with placenta accreta and very rare irregular antibodies versus Cromer blood group system: a case report
  149. Effect of Performance Improvement Programs on Compliance with Sepsis Bundles and Mortality: A Systematic Review and Meta-Analysis of Observational Studies
  150. Arterial hyperoxia and mortality in critically ill patients: a systematic review and meta-analysis
  151. Trends in ventilator-associated pneumonia: Impact of a ventilator care bundle in an Italian tertiary care hospital intensive care unit
  152. World Society of Emergency Surgery (WSES) guidelines for management of skin and soft tissue infections
  153. Wernicke’s encephalopathy in a malnourished surgical patient: a difficult diagnosis
  154. Early therapy with IgM-enriched polyclonal immunoglobulin in patients with septic shock
  155. Clinical performance of a commercial real-time PCR assay for Aspergillus DNA detection in serum samples from high-risk patients: comparison with a galactomannan enzyme immunoassay
  156. Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit
  157. Erratum to: An Italian consensus for invasive candidiasis management (ITALIC)
  158. Loss of Self-Regulation in Interstitial Fluid Dynamics of Septic Patients, and Oedema Development Patterns
  159. Immunoglobulin as Adjunctive Therapy in Sepsis
  160. Effect of Heart Rate Control With Esmolol on Hemodynamic and Clinical Outcomes in Patients With Septic Shock
  161. A Janus role for MerTK in the outcome of septic shock
  162. Endotoxin activity levels as a prediction tool for risk of deterioration in patients with sepsis not admitted to the intensive care unit: A pilot observational study
  163. The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome
  164. Characterization of Specific Immune Responses to Different Aspergillus Antigens during the Course of Invasive Aspergillosis in Hematologic Patients
  165. Characteristics and outcome predictors of patients involved in an outbreak of Burkholderia cepacia complex
  166. Hemostasis in acute liver and kidney failure: nothing is as it seems
  167. Aggressive versus conservative initiation of antibiotics
  168. Effectiveness of sepsis bundle application in cirrhotic patients with septic shock: a single-center experience
  169. Early alterations of B cells in patients with septic shock: another piece in the complex puzzle of the immune response in sepsis
  170. Successful liver transplantation in a patient with splanchnic vein thrombosis and pulmonary embolism due to polycythemia vera with Jak2v617f mutation and heparin-induced thrombocytopenia
  171. Levosimendan in a case of severe peri-myocarditis associated with influenza A/H1N1 virus
  172. Hospital staff education on severe sepsis/septic shock and hospital mortality: an original hypothesis
  173. A new technique for percutaneous dilatational tracheostomy (G-Trach): preliminary experience in pigs
  174. Abdominal Compartment Syndrome and Fluid Replacement: A Dog That Bites Its Own Tail?
  175. Erratum
  176. PSP/reg: a new stone in sepsis biomarkers?
  177. Massive bleeding: Are we doing our best?
  178. Acute Renal Failure and Renal Replacement Therapy in the Postoperative Period of Orthotopic Liver Transplant Patients Versus Nonelective Abdominal Surgery Patients
  179. Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection
  180. Posttraumatic massive bleeding: a challenging multidisciplinary task
  181. Levosimendan in Cardiac Failure After Subarachnoid Hemorrhage
  182. Two-stage liver transplantation: an effective procedure in urgent conditions
  183. Perioperative Red Blood Cell Transfusion and Outcome in Stable Patients after Elective Major Vascular Surgery
  184. Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study
  185. Use of activated protein c in liver transplantation patients with septic shock
  186. Incidence and Clinical Outcomes of Ventilator-Associated Pneumonia in Liver Transplant and Non-Liver Transplant Surgical Patients
  187. Recombinant Activated Factor VII in Critical Bleeding After Orthotopic Liver Transplantation
  188. Strategies to Control Massive Abdominal Bleeding
  189. A modified goal-directed protocol improves clinical outcome in intensive care unit patients with septic shock patients
  190. Liver transplantation in HIV patients
  191. Peri-operative respiratory failure in a cirrhotic patient: a misleading diagnosis
  192. Gram-Positive Bloodstream Infections in Liver Transplant Recipients: Incidence, Risk Factors, and Impact on Survival
  193. Intracerebral haemorrhage: an often neglected medical emergency
  194. Living Donor Liver Transplantation and Management of Portal Venous Pressure
  195. Intra-abdominal Hypertension in Nonelective Surgery: A Preliminary Report
  196. Posttransplant Cerebral Hemorrhage in a Patient with Familial Amyloidotic Polyneuropathy
  197. Rectal amputation sparing by haemostatic therapy with recombinant factor VIIa in a patient with cytomegalovirus–related colitis
  198. More on: platelet count and the Use of Recombinant Factor VIIa for the treatment of Bleeding Complications after Hematopoietic Stem Cell Transplantation
  199. Comment on: ?Hemodynamic response to coupled plasmafiltration-adsorption in human septic shock? by Formica et al.
  200. Muscle perfusion and oxygen consumption by near-infrared spectroscopy in septic-shock and non-septic-shock patients
  201. Extravascular lung water and intravascular volume monitoring
  202. Pain management after small bowel/multivisceral transplantation
  203. Prevention of post-herpetic neuralgia: acyclovir and prednisolone versus epidural local anesthetic and methylprednisolone
  204. Oxygen cost of dynamic leg exercise on a cycle ergometer: effects of gravity acceleration
  205. Severe hypoxemia and pulmonary hypertension during orthotopic liver transplantation: a successful use of inhaled nitric oxide
  206. Effects of prolonged bed rest on cardiovascular oxygen transport during submaximal exercise in humans
  207. Effects of elastic recoil on maximal explosive power of the lower limbs
  208. The Effect of Laparoscopic Cholecystectomy on Cardiovascular Function and Pulmonary Gas Exchange
  209. The Effect of Laparoscopic Cholecystectomy on Cardiovascular Function and Pulmonary Gas Exchange
  210. Oxygen cost of internal work during cycling
  211. Noninvasive assessment of cardiac output from arterial pressure profiles during exercise
  212. Assessment of cardiac output from noninvasive determination of arterial pressure profile in subjects at rest
  213. Effects of prolonged cycle ergometer exercise on maximal muscle power and oxygen uptake in humans
  214. Severe bleeding in critical care