All Stories

  1. Acquisition Origin Matters: Clinical, Microbiological and Immunological Characteristics and Treatment Effects in Community- vs. Hospital-Acquired Septic Shock
  2. Rehabilitation and physiotherapists in the critical care medicine
  3. Perioperative Use of IgM-Enriched Immunoglobulins in Liver Transplantation Recipients at High Risk for Infections: A Preliminary Study
  4. Association between respiratory distress time and invasive mechanical ventilation in COVID-19 patients: A multicentre regional cohort study
  5. The Interplay between Antibiotics and the Host Immune Response in Sepsis: From Basic Mechanisms to Clinical Considerations: A Comprehensive Narrative Review
  6. Advances and Challenges in Sepsis Management: Modern Tools and Future Directions
  7. The Association of Procalcitonin and C-Reactive Protein with Bacterial Infections Acquired during Intensive Care Unit Stay in COVID-19 Critically Ill Patients
  8. Role of Selective Digestive Decontamination in the Prevention of Ventilator-Associated Pneumonia in COVID-19 Patients: A Pre-Post Observational Study
  9. Do All Critically Ill Patients with COVID-19 Disease Benefit from Adding Tocilizumab to Glucocorticoids? A Retrospective Cohort Study
  10. Ceftazidime/Avibactam in Ventilator-Associated Pneumonia Due to Difficult-to-Treat Non-Fermenter Gram-Negative Bacteria in COVID-19 Patients: A Case Series and Review of the Literature
  11. Patients Recovering from Severe COVID-19 Develop a Polyfunctional Antigen-Specific CD4+ T Cell Response
  12. Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis: an international cohort study
  13. Long-Term Impact of the COVID-19 Pandemic on In-Hospital Antibiotic Consumption and Antibiotic Resistance: A Time Series Analysis (2015–2021)
  14. Communication and visiting policies in Italian intensive care units during the first COVID-19 pandemic wave and lockdown: a nationwide survey
  15. Molecular and cellular immune features of aged patients with severe COVID-19 pneumonia
  16. Carriers of ADAMTS13 Rare Variants Are at High Risk of Life-Threatening COVID-19
  17. Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality
  18. Early awake proning in critical and severe COVID-19 patients undergoing noninvasive respiratory support: A retrospective multicenter cohort study
  19. Risk Factors for Pulmonary Air Leak and Clinical Prognosis in Patients With COVID-19 Related Acute Respiratory Failure: A Retrospective Matched Control Study
  20. Nasal pressure swings as the measure of inspiratory effort in spontaneously breathing patients with de novo acute respiratory failure
  21. Plasma Cytokine Atlas Reveals the Importance of TH2 Polarization and Interferons in Predicting COVID-19 Severity and Survival
  22. Editorial: Putting the Spotlight on the Role of Oxygen in Critically-Ill Patients: From Basic Mechanisms to Clinical Effects
  23. Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study
  24. Correction: Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia
  25. First and second waves among hospitalised patients with COVID-19 with severe pneumonia: a comparison of 28-day mortality over the 1-year pandemic in a tertiary university hospital in Italy
  26. The effect of non-invasive ventilation on intra-abdominal pressure
  27. Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients
  28. Metabolic reprograming shapes neutrophil functions in severe COVID‐19
  29. Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity
  30. Development of post-COVID-19 cardiovascular events: an analysis of clinical features and risk factors from a single hospital retrospective study
  31. Mapping the human genetic architecture of COVID-19: an update
  32. Acquisition of skills in critical emergency medicine: an experimental study on the SIAARTI Academy CREM experience
  33. Revisited Hyperoxia Pathophysiology in the Perioperative Setting: A Narrative Review
  34. Correction to: Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial
  35. Vertebral artery dissection in term pregnancy after cervical spine manipulation: a case report and review the literature
  36. Author Correction: Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
  37. Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia
  38. Inspiratory Effort and Lung Mechanics in Spontaneously Breathing Patients with Acute Respiratory Failure due to COVID-19: A Matched Control Study
  39. Synergistic Effect of Static Compliance and D-dimers to Predict Outcome of Patients with COVID-19-ARDS: A Prospective Multicenter Study
  40. Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity
  41. A pandemic recap: lessons we have learned
  42. Herpes Simplex Virus Re-Activation in Patients with SARS-CoV-2 Pneumonia: A Prospective, Observational Study
  43. Exogenous pulmonary surfactant in COVID-19 ARDS. The similarities to neonatal RDS suggest a new scenario for an ‘old’ strategy
  44. A five-component infection control bundle to permanently eliminate a carbapenem-resistant Acinetobacter baumannii spreading in an intensive care unit
  45. The impact of tocilizumab on respiratory support states transition and clinical outcomes in COVID-19 patients. A Markov model multi-state study
  46. Rationale for Polyclonal Intravenous Immunoglobulin Adjunctive Therapy in COVID-19 Patients: Report of a Structured Multidisciplinary Consensus
  47. Better prognosis in females with severe COVID-19 pneumonia: possible role of inflammation as potential mediator
  48. Hospital-Acquired Infections in Critically Ill Patients With COVID-19
  49. Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection
  50. Mapping the human genetic architecture of COVID-19
  51. One‐year persistence of neutralizing anti‐SARS‐CoV‐2 antibodies in dialysis patients recovered from COVID‐19
  52. Incidence, risk factors and outcome of acute kidney injury (AKI) in patients with COVID-19
  53. C9orf72 Intermediate Repeats Confer Genetic Risk for Severe COVID-19 Pneumonia Independently of Age
  54. Monocyte Distribution Width (MDW) as novel inflammatory marker with prognostic significance in COVID-19 patients
  55. Acid base disorders in patients with COVID-19
  56. Good clinical practice for the use of vasopressor and inotropic drugs in critically ill patients: state-of-the-art and expert consensus
  57. The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
  58. SELP Asp603Asn and severe thrombosis in COVID-19 males: implication for anti P-selectin monoclonal antibodies treatment
  59. Mergers and acquisitions in emerging markets: What drives absorptive capacity in target firms?
  60. Identification and characterization of a SARS-CoV-2 specific CD8+ T cell response with immunodominant features
  61. Never Give Up: Lesson learned from a severe COVID-19 patient
  62. Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients
  63. An update on levosimendan in acute cardiac care: applications and recommendations for optimal efficacy and safety
  64. Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge
  65. The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males
  66. Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study
  67. Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males
  68. Development and validation of a prediction model for tocilizumab failure in hospitalized patients with SARS-CoV-2 infection
  69. Adjunctive Immunotherapy With Polyclonal Ig-M Enriched Immunoglobulins for Septic Shock: From Bench to Bedside. The Rationale for a Personalized Treatment Protocol
  70. Incidence and Prognosis of Ventilator-Associated Pneumonia in Critically Ill Patients with COVID-19: A Multicenter Study
  71. Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)
  72. Post-Mendelian genetic model in COVID-19
  73. Employing a systematic approach to biobanking and analyzing clinical and genetic data for advancing COVID-19 research
  74. Hypokalemia in Patients with COVID-19
  75. Cluster analysis identifies patients at risk of catheter-associated urinary tract infections in intensive care units: findings from the SPIN-UTI Network
  76. Genetic mechanisms of critical illness in Covid-19
  77. Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study
  78. Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males
  79. Clinical and molecular characterization of COVID-19 hospitalized patients
  80. Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia—Challenges, strengths, and opportunities in a global health emergency
  81. Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in males
  82. Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia
  83. Testicular pain as an unusual presentation of COVID-19: a brief review of SARS-CoV-2 and the testis
  84. Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy
  85. Best-practice IgM- and IgA-enriched immunoglobulin use in patients with sepsis
  86. Adjunctive therapy with vitamin c and thiamine in patients treated with steroids for refractory septic shock: A propensity matched before-after, case-control study
  87. COVID-19-associated vasculitis and thrombotic complications: from pathological findings to multidisciplinary discussion
  88. The predictive value of fruit juice in the esophagus-pleural fistula
  89. Two Fatal Cases of Acute Liver Failure Due to HSV-1 Infection in COVID-19 Patients Following Immunomodulatory Therapies
  90. Multi-centre, three arm, randomized controlled trial on the use of methylprednisolone and unfractionated heparin in critically ill ventilated patients with pneumonia from SARS-CoV-2 infection: A structured summary of a study protocol for a randomised c...
  91. Early Inspiratory Effort Assessment by Esophageal Manometry Predicts Noninvasive Ventilation Outcome in De Novo Respiratory Failure. A Pilot Study
  92. Expansion of plasmablasts and loss of memory B cells in peripheral blood from COVID‐19 patients with pneumonia
  93. Tocilizumab in patients with severe COVID-19: a retrospective cohort study
  94. Employing a Systematic Approach to Biobanking and Analyzing Clinical and Genetic Data for Advancing COVID-19 Research
  95. Guide-wire replacement of a mini-midline catheter with a central venous catheter: A retrospective study on 63 cases
  96. ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population
  97. Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia
  98. Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use
  99. Incidence, Risk Factors and Mortality Outcome in Patients with Acute Kidney Injury in COVID-19: A Single-Center Observational Study
  100. A case of splenic artery pseudoaneurysm rupture in a bulimic patient with gastric ulcer
  101. Reply to “Indications and timing for tracheostomy in patients with SARS CoV2‐related” by Ferri et al.
  102. Hypokalemia in Patients with COVID-19
  103. Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study
  104. Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia - challenges, strengths, and opportunities in a global health emergency
  105. Clinical and molecular characterization of COVID-19 hospitalized patients
  106. Increased Plasma Levels of Mitochondrial DNA and Normal Inflammasome Gene Expression in Monocytes Characterize Patients With Septic Shock Due to Multidrug Resistant Bacteria
  107. The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database
  108. Tracheostomy in the COVID-19 pandemic
  109. Ceftolozane/Tazobactam for Treatment of Severe ESBL-Producing Enterobacterales Infections: A Multicenter Nationwide Clinical Experience (CEFTABUSE II Study)
  110. Handling and Processing of Blood Specimens from Patients with COVID‐19 for Safe Studies on Cell Phenotype and Cytokine Storm
  111. SARS‐CoV‐2, the Virus that Causes COVID‐19: Cytometry and the New Challenge for Global Health
  112. Case report of a patient who survived after cardiac arrest and cardiogenic shock by anaphylactic reaction to gadolinium during magnetic resonance imaging
  113. Shorter Androgen Receptor PolyQ Alleles Protect Against Life-Threatening COVID-19 Disease in Males
  114. OUP accepted manuscript
  115. Surfactant replacement might help recovery of low-compliance lung in severe COVID-19 pneumonia
  116. Current gaps in sepsis immunology: new opportunities for translational research
  117. University of Modena Experience With Liver Grafts From Donation After Circulatory Death: What Really Matters in Organ Selection?
  118. Epidemiology of intra-abdominal infection and sepsis in critically ill patients: “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project
  119. Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project
  120. What’s new in oxygen therapy?
  121. Oxygen: a powerful drug to handle with care
  122. Cytoreductive surgery and HIPEC in a 14 years old patient with peritoneal recurrence of adenocarcinoma of the right colon
  123. Use of Levosimendan in Intensive Care Unit Settings
  124. Landiolol in patients with septic shock resident in an intensive care unit (LANDI-SEP): study protocol for a randomized controlled trial
  125. JLB: a new long-cannula venous catheter
  126. Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature
  127. Real-time monitoring of Pseudomonas aeruginosa biofilm formation on endotracheal tubes in vitro
  128. Experienced Use of Dexmedetomidine in the Intensive Care Unit: A Report of a Structured Consensus
  129. Prognostic Potential of the Panfungal Marker (1 → 3)-β-d-Glucan in Invasive Mycoses Patients
  130. Procalcitonin-guided antibiotic therapy: an expert consensus
  131. Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)
  132. Oxygen in the critically ill
  133. The prognostic importance of chronic end-stage diseases in geriatric patients admitted to 163 Italian ICUs
  134. Correction to: The Intensive Care Global Study on Severe Acute Respiratory Infection (IC-GLOSSARI): a multicenter, multinational, 14-day inception cohort study
  135. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway
  136. Common Practice and Guidelines for Sedation in Critically Ill Patients
  137. Randomized, multicenter trial of lateral Trendelenburg versus semirecumbent body position for the prevention of ventilator-associated pneumonia
  138. Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference
  139. Effects of short-term hyperoxia on erythropoietin levels and microcirculation in critically Ill patients: a prospective observational pilot study
  140. Injury-induced immunosuppression: are we finally on the right track?
  141. Oxygen Supplementation Among Patients in the Intensive Care Unit
  142. Mortality in Patients With Septic Shock by Multidrug Resistant Bacteria
  143. Impact of Pre-Analytical Time on the Recovery of Pathogens from Blood Cultures: Results from a Large Retrospective Survey
  144. The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDR/XDR Infections
  145. Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit
  146. Dexmedetomidine for agitated delirium in intensive care unit intubated patients
  147. Evaluation of serum (1 → 3)-β-d-glucan clinical performance: kinetic assessment, comparison with galactomannan and evaluation of confounding factors
  148. A one-year prospective study of refractory status epilepticus in Modena, Italy
  149. The Surviving Sepsis Campaign bundles and outcome: results from the International Multicentre Prevalence Study on Sepsis (the IMPreSS study)
  150. A challenging case of pregnancy with placenta accreta and very rare irregular antibodies versus Cromer blood group system: a case report
  151. Effect of Performance Improvement Programs on Compliance with Sepsis Bundles and Mortality: A Systematic Review and Meta-Analysis of Observational Studies
  152. Arterial hyperoxia and mortality in critically ill patients: a systematic review and meta-analysis
  153. Trends in ventilator-associated pneumonia: Impact of a ventilator care bundle in an Italian tertiary care hospital intensive care unit
  154. World Society of Emergency Surgery (WSES) guidelines for management of skin and soft tissue infections
  155. Wernicke’s encephalopathy in a malnourished surgical patient: a difficult diagnosis
  156. Early therapy with IgM-enriched polyclonal immunoglobulin in patients with septic shock
  157. Clinical performance of a commercial real-time PCR assay for Aspergillus DNA detection in serum samples from high-risk patients: comparison with a galactomannan enzyme immunoassay
  158. Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit
  159. Erratum to: An Italian consensus for invasive candidiasis management (ITALIC)
  160. Loss of Self-Regulation in Interstitial Fluid Dynamics of Septic Patients, and Oedema Development Patterns
  161. Immunoglobulin as Adjunctive Therapy in Sepsis
  162. Effect of Heart Rate Control With Esmolol on Hemodynamic and Clinical Outcomes in Patients With Septic Shock
  163. A Janus role for MerTK in the outcome of septic shock
  164. Endotoxin activity levels as a prediction tool for risk of deterioration in patients with sepsis not admitted to the intensive care unit: A pilot observational study
  165. The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome
  166. Characterization of Specific Immune Responses to Different Aspergillus Antigens during the Course of Invasive Aspergillosis in Hematologic Patients
  167. Characteristics and outcome predictors of patients involved in an outbreak of Burkholderia cepacia complex
  168. Hemostasis in acute liver and kidney failure: nothing is as it seems
  169. Aggressive versus conservative initiation of antibiotics
  170. Effectiveness of sepsis bundle application in cirrhotic patients with septic shock: a single-center experience
  171. Early alterations of B cells in patients with septic shock: another piece in the complex puzzle of the immune response in sepsis
  172. Successful liver transplantation in a patient with splanchnic vein thrombosis and pulmonary embolism due to polycythemia vera with Jak2v617f mutation and heparin-induced thrombocytopenia
  173. Levosimendan in a case of severe peri-myocarditis associated with influenza A/H1N1 virus
  174. Hospital staff education on severe sepsis/septic shock and hospital mortality: an original hypothesis
  175. A new technique for percutaneous dilatational tracheostomy (G-Trach): preliminary experience in pigs
  176. Abdominal Compartment Syndrome and Fluid Replacement: A Dog That Bites Its Own Tail?
  177. Erratum
  178. PSP/reg: a new stone in sepsis biomarkers?
  179. Massive bleeding: Are we doing our best?
  180. Acute Renal Failure and Renal Replacement Therapy in the Postoperative Period of Orthotopic Liver Transplant Patients Versus Nonelective Abdominal Surgery Patients
  181. Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection
  182. Posttraumatic massive bleeding: a challenging multidisciplinary task
  183. Levosimendan in Cardiac Failure After Subarachnoid Hemorrhage
  184. Two-stage liver transplantation: an effective procedure in urgent conditions
  185. Perioperative Red Blood Cell Transfusion and Outcome in Stable Patients after Elective Major Vascular Surgery
  186. Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study
  187. Use of activated protein c in liver transplantation patients with septic shock
  188. Incidence and Clinical Outcomes of Ventilator-Associated Pneumonia in Liver Transplant and Non-Liver Transplant Surgical Patients
  189. Recombinant Activated Factor VII in Critical Bleeding After Orthotopic Liver Transplantation
  190. Strategies to Control Massive Abdominal Bleeding
  191. A modified goal-directed protocol improves clinical outcome in intensive care unit patients with septic shock patients
  192. Liver transplantation in HIV patients
  193. Peri-operative respiratory failure in a cirrhotic patient: a misleading diagnosis
  194. Gram-Positive Bloodstream Infections in Liver Transplant Recipients: Incidence, Risk Factors, and Impact on Survival
  195. Intracerebral haemorrhage: an often neglected medical emergency
  196. Living Donor Liver Transplantation and Management of Portal Venous Pressure
  197. Intra-abdominal Hypertension in Nonelective Surgery: A Preliminary Report
  198. Posttransplant Cerebral Hemorrhage in a Patient with Familial Amyloidotic Polyneuropathy
  199. Rectal amputation sparing by haemostatic therapy with recombinant factor VIIa in a patient with cytomegalovirus–related colitis
  200. More on: platelet count and the Use of Recombinant Factor VIIa for the treatment of Bleeding Complications after Hematopoietic Stem Cell Transplantation
  201. Comment on: ?Hemodynamic response to coupled plasmafiltration-adsorption in human septic shock? by Formica et al.
  202. Muscle perfusion and oxygen consumption by near-infrared spectroscopy in septic-shock and non-septic-shock patients
  203. Extravascular lung water and intravascular volume monitoring
  204. Pain management after small bowel/multivisceral transplantation
  205. Prevention of post-herpetic neuralgia: acyclovir and prednisolone versus epidural local anesthetic and methylprednisolone
  206. Oxygen cost of dynamic leg exercise on a cycle ergometer: effects of gravity acceleration
  207. Severe hypoxemia and pulmonary hypertension during orthotopic liver transplantation: a successful use of inhaled nitric oxide
  208. Effects of prolonged bed rest on cardiovascular oxygen transport during submaximal exercise in humans
  209. Effects of elastic recoil on maximal explosive power of the lower limbs
  210. The Effect of Laparoscopic Cholecystectomy on Cardiovascular Function and Pulmonary Gas Exchange
  211. The Effect of Laparoscopic Cholecystectomy on Cardiovascular Function and Pulmonary Gas Exchange
  212. Oxygen cost of internal work during cycling
  213. Noninvasive assessment of cardiac output from arterial pressure profiles during exercise
  214. Assessment of cardiac output from noninvasive determination of arterial pressure profile in subjects at rest
  215. Effects of prolonged cycle ergometer exercise on maximal muscle power and oxygen uptake in humans
  216. Severe bleeding in critical care
  217. New frontiers in critical bleeding