All Stories

  1. Monocyte Distribution Width (MDW) as an Early Biomarker of Blood Culture Positivity and Clinically Significant Bloodstream Infection in Emergency Department: A Real-World Study

    Article • July 2026, MDPI AG

    MD Massimo Girardis

  2. Acquisition Origin Matters: Clinical, Microbiological and Immunological Characteristics and Treatment Effects in Community- vs. Hospital-Acquired Septic Shock

    Article • Antibiotics, February 2026, MDPI AG

    MD Massimo Girardis

  3. Author Correction: Hemoadsorption in septic shock—CON

    Article • Intensive Care Medicine, June 2025, Springer Science + Business Media

    MD Massimo Girardis

  4. Hemoadsorption in septic shock – CON

    Article • Intensive Care Medicine, May 2025, Springer Science + Business Media

    MD Massimo Girardis

  5. Rezafungin versus caspofungin for patients with candidaemia or invasive candidiasis in the intensive care unit: pooled analyses of the ReSTORE and STRIVE randomised trials

    Article • Critical Care, October 2024, Springer Science + Business Media

    MD Massimo Girardis

  6. Rehabilitation and physiotherapists in the critical care medicine

    Article • Pulmonology, October 2024, Taylor & Francis

    Professor Enrico M. Clini, MD Massimo Girardis

  7. Understanding, assessing and treating immune, endothelial and haemostasis dysfunctions in bacterial sepsis

    Article • Intensive Care Medicine, September 2024, Springer Science + Business Media

    MD Massimo Girardis

  8. Perioperative Use of IgM-Enriched Immunoglobulins in Liver Transplantation Recipients at High Risk for Infections: A Preliminary Study

    Article • Journal of Clinical Medicine, August 2024, MDPI AG

    MD Massimo Girardis

  9. Association between respiratory distress time and invasive mechanical ventilation in COVID-19 patients: A multicentre regional cohort study

    Article • Pulmonology, May 2024, Taylor & Francis

    MD Massimo Girardis, Professor Enrico M. Clini

  10. Adjunctive immunotherapeutic agents in patients with sepsis and septic shock: a multidisciplinary consensus of 23

    Article • Journal of Anesthesia Analgesia and Critical Care, April 2024, Springer Science + Business Media

    MD Massimo Girardis

  11. The Interplay between Antibiotics and the Host Immune Response in Sepsis: From Basic Mechanisms to Clinical Considerations: A Comprehensive Narrative Review

    Article • Antibiotics, April 2024, MDPI AG

    MD Massimo Girardis

  12. Advances and Challenges in Sepsis Management: Modern Tools and Future Directions

    Article • Cells, March 2024, MDPI AG

    MD Massimo Girardis

  13. The Association of Procalcitonin and C-Reactive Protein with Bacterial Infections Acquired during Intensive Care Unit Stay in COVID-19 Critically Ill Patients

    Article • Antibiotics, October 2023, MDPI AG

    MD Massimo Girardis, Professor Enrico M. Clini

  14. Trials on oxygen targets in the critically ill patients: do they change our knowledge and practice?

    Article • Intensive Care Medicine, March 2023, Springer Science + Business Media

    MD Massimo Girardis

  15. Role of Selective Digestive Decontamination in the Prevention of Ventilator-Associated Pneumonia in COVID-19 Patients: A Pre-Post Observational Study

    Article • Journal of Clinical Medicine, February 2023, MDPI AG

    MD Massimo Girardis, Professor Enrico M. Clini

  16. Do All Critically Ill Patients with COVID-19 Disease Benefit from Adding Tocilizumab to Glucocorticoids? A Retrospective Cohort Study

    Article • Viruses, January 2023, MDPI AG

    MD Massimo Girardis, Professor Enrico M. Clini

  17. Source control in the management of sepsis and septic shock

    Article • Intensive Care Medicine, September 2022, Springer Science + Business Media

    MD Massimo Girardis

  18. Ceftazidime/Avibactam in Ventilator-Associated Pneumonia Due to Difficult-to-Treat Non-Fermenter Gram-Negative Bacteria in COVID-19 Patients: A Case Series and Review of the Literature

    Article • Antibiotics, July 2022, MDPI AG

    MD Massimo Girardis

  19. Patients Recovering from Severe COVID-19 Develop a Polyfunctional Antigen-Specific CD4+ T Cell Response

    Article • International Journal of Molecular Sciences, July 2022, MDPI AG

    MD Massimo Girardis

  20. Epidemiology and age-related mortality in critically ill patients with intra-abdominal infection or sepsis: an international cohort study

    Article • International Journal of Antimicrobial Agents, July 2022, Elsevier

    MD Massimo Girardis

  21. Long-Term Impact of the COVID-19 Pandemic on In-Hospital Antibiotic Consumption and Antibiotic Resistance: A Time Series Analysis (2015–2021)

    Article • Antibiotics, June 2022, MDPI AG

    MD Massimo Girardis

  22. Communication and visiting policies in Italian intensive care units during the first COVID-19 pandemic wave and lockdown: a nationwide survey

    Article • BMC Anesthesiology, June 2022, Springer Science + Business Media

    MD Massimo Girardis

  23. Molecular and cellular immune features of aged patients with severe COVID-19 pneumonia

    Article • Communications Biology, June 2022, Springer Science + Business Media

    MD Massimo Girardis

  24. Carriers of ADAMTS13 Rare Variants Are at High Risk of Life-Threatening COVID-19

    Article • Viruses, May 2022, MDPI AG

    MD Massimo Girardis

  25. Cytomegalovirus blood reactivation in COVID-19 critically ill patients: risk factors and impact on mortality

    Article • Intensive Care Medicine, May 2022, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  26. Early awake proning in critical and severe COVID-19 patients undergoing noninvasive respiratory support: A retrospective multicenter cohort study

    Article • Pulmonology, May 2022, Taylor & Francis

    MD Massimo Girardis, Professor Enrico M. Clini

  27. Risk Factors for Pulmonary Air Leak and Clinical Prognosis in Patients With COVID-19 Related Acute Respiratory Failure: A Retrospective Matched Control Study

    Article • Frontiers in Medicine, March 2022, Frontiers

    MD Massimo Girardis, Professor Enrico M. Clini

  28. Nasal pressure swings as the measure of inspiratory effort in spontaneously breathing patients with de novo acute respiratory failure

    Article • Critical Care, March 2022, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  29. Plasma Cytokine Atlas Reveals the Importance of TH2 Polarization and Interferons in Predicting COVID-19 Severity and Survival

    Article • Frontiers in Immunology, March 2022, Frontiers

    MD Massimo Girardis

  30. Editorial: Putting the Spotlight on the Role of Oxygen in Critically-Ill Patients: From Basic Mechanisms to Clinical Effects

    Article • Frontiers in Medicine, February 2022, Frontiers

    MD Massimo Girardis

  31. Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study

    Article • Infectious Diseases and Therapy, February 2022, Springer Science + Business Media

    MD Massimo Girardis

  32. Correction: Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia

    Article • BMC Pulmonary Medicine, February 2022, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  33. First and second waves among hospitalised patients with COVID-19 with severe pneumonia: a comparison of 28-day mortality over the 1-year pandemic in a tertiary university hospital in Italy

    Article • BMJ Open, January 2022, BMJ

    MD Massimo Girardis, Professor Enrico M. Clini

  34. The effect of non-invasive ventilation on intra-abdominal pressure

    Article • Anaesthesiology Intensive Therapy, January 2022, Termedia Sp. z.o.o.

    MD Massimo Girardis

  35. Rare variants in Toll-like receptor 7 results in functional impairment and downregulation of cytokine-mediated signaling in COVID-19 patients

    Article • Genes & Immunity, December 2021, Springer Science + Business Media

    Roberta Russo, MD Massimo Girardis

  36. Metabolic reprograming shapes neutrophil functions in severe COVID‐19

    Article • European Journal of Immunology, December 2021, Wiley

    MD Massimo Girardis

  37. Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity

    Article • Human Genetics, December 2021, Springer Science + Business Media

    Roberta Russo, MD Massimo Girardis, Hugh Montgomery

  38. Development of post-COVID-19 cardiovascular events: an analysis of clinical features and risk factors from a single hospital retrospective study

    Article • Infezioni in Medicina, December 2021, Edizioni Internazionali srl, Divisione EDIMES Edizioni Medico-Scientifiche

    MD Massimo Girardis, Professor Enrico M. Clini

  39. Mapping the human genetic architecture of COVID-19: an update

    Article • November 2021, Cold Spring Harbor Laboratory Press

    MD Massimo Girardis, Roberta Russo

  40. Acquisition of skills in critical emergency medicine: an experimental study on the SIAARTI Academy CREM experience

    Article • Minerva Anestesiologica, November 2021, Edizioni Minerva Medica

    MD Massimo Girardis

  41. Revisited Hyperoxia Pathophysiology in the Perioperative Setting: A Narrative Review

    Article • Frontiers in Medicine, October 2021, Frontiers

    MD Massimo Girardis

  42. Correction to: Tocilizumab for patients with COVID-19 pneumonia. The single-arm TOCIVID-19 prospective trial

    Article • Journal of Translational Medicine, October 2021, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini, Dr marco cascella

  43. Vertebral artery dissection in term pregnancy after cervical spine manipulation: a case report and review the literature

    Article • Journal of Medical Case Reports, October 2021, Springer Science + Business Media

    MD Massimo Girardis

  44. Author Correction: Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection

    Article • Nature Communications, September 2021, Springer Science + Business Media

    MD Massimo Girardis

  45. Endobronchial valve positioning for alveolar-pleural fistula following ICU management complicating COVID-19 pneumonia

    Article • BMC Pulmonary Medicine, September 2021, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  46. Inspiratory Effort and Lung Mechanics in Spontaneously Breathing Patients with Acute Respiratory Failure due to COVID-19: A Matched Control Study

    Article • American Journal of Respiratory and Critical Care Medicine, September 2021, American Thoracic Society

    MD Massimo Girardis, Professor Enrico M. Clini

  47. Synergistic Effect of Static Compliance and D-dimers to Predict Outcome of Patients with COVID-19-ARDS: A Prospective Multicenter Study

    Article • Biomedicines, September 2021, MDPI AG

    MD Massimo Girardis

  48. Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity

    Article • September 2021, Cold Spring Harbor Laboratory Press

    Roberta Russo, MD Massimo Girardis

  49. A pandemic recap: lessons we have learned

    Article • World Journal of Emergency Surgery, September 2021, Springer Science + Business Media

    Prof. Majdi Al-Hasan, Evgeni Dimitrov, MD Massimo Girardis, Dr Timothy Craig Hardcastle

  50. Herpes Simplex Virus Re-Activation in Patients with SARS-CoV-2 Pneumonia: A Prospective, Observational Study

    Article • Microorganisms, September 2021, MDPI AG

    MD Massimo Girardis, Professor Enrico M. Clini

  51. Exogenous pulmonary surfactant in COVID-19 ARDS. The similarities to neonatal RDS suggest a new scenario for an ‘old’ strategy

    Article • BMJ Open Respiratory Research, September 2021, BMJ

    MD Massimo Girardis

  52. A five-component infection control bundle to permanently eliminate a carbapenem-resistant Acinetobacter baumannii spreading in an intensive care unit

    Article • Antimicrobial Resistance and Infection Control, August 2021, Springer Science + Business Media

    MD Massimo Girardis

  53. The impact of tocilizumab on respiratory support states transition and clinical outcomes in COVID-19 patients. A Markov model multi-state study

    Article • PLOS One, August 2021, PLOS

    MD Massimo Girardis

  54. Rationale for Polyclonal Intravenous Immunoglobulin Adjunctive Therapy in COVID-19 Patients: Report of a Structured Multidisciplinary Consensus

    Article • Journal of Clinical Medicine, August 2021, MDPI AG

    MD Massimo Girardis

  55. Better prognosis in females with severe COVID-19 pneumonia: possible role of inflammation as potential mediator

    Article • Clinical Microbiology and Infection, August 2021, Elsevier

    MD Massimo Girardis, Professor Enrico M. Clini

  56. Hospital-Acquired Infections in Critically Ill Patients With COVID-19

    Article • CHEST Journal, August 2021, Elsevier

    MD Massimo Girardis

  57. Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection

    Article • Nature Communications, July 2021, Springer Science + Business Media

    MD Massimo Girardis

  58. Mapping the human genetic architecture of COVID-19

    Article • Nature, July 2021, Springer Science + Business Media

    Michael Olanipekun, Professor Ahilanandan Dushianthan, Roberta Russo, MD Massimo Girardis, Hugh Montgomery, Dr Hong Bin Kim, Lise Tuset Gustad, JUNICHI SASAKI, Dr Roberta Gualtierotti

  59. One‐year persistence of neutralizing anti‐SARS‐CoV‐2 antibodies in dialysis patients recovered from COVID‐19

    Article • Hemodialysis International, July 2021, Wiley

    MD Massimo Girardis

  60. Incidence, risk factors and outcome of acute kidney injury (AKI) in patients with COVID-19

    Article • Clinical and Experimental Nephrology, July 2021, Springer Science + Business Media

    MD Massimo Girardis

  61. C9orf72 Intermediate Repeats Confer Genetic Risk for Severe COVID-19 Pneumonia Independently of Age

    Article • International Journal of Molecular Sciences, June 2021, MDPI AG

    Roberta Russo, MD Massimo Girardis

  62. Monocyte Distribution Width (MDW) as novel inflammatory marker with prognostic significance in COVID-19 patients

    Article • Scientific Reports, June 2021, Springer Science + Business Media

    MD Massimo Girardis

  63. Acid base disorders in patients with COVID-19

    Article • International Urology and Nephrology, June 2021, Springer Science + Business Media

    MD Massimo Girardis

  64. Good clinical practice for the use of vasopressor and inotropic drugs in critically ill patients: state-of-the-art and expert consensus

    Article • Minerva Anestesiologica, June 2021, Edizioni Minerva Medica

    MD Massimo Girardis

  65. The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity

    Article • The Lancet Respiratory Medicine, June 2021, Elsevier

    MD Massimo Girardis, Dr CATIA CILLONIZ

  66. SELP Asp603Asn and severe thrombosis in COVID-19 males: implication for anti P-selectin monoclonal antibodies treatment

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Roberta Russo, MD Massimo Girardis

  67. Mergers and acquisitions in emerging markets: What drives absorptive capacity in target firms?

    Article • South African Journal of Business Management, May 2021, AOSIS Open Journals

    MD Massimo Girardis

  68. Identification and characterization of a SARS-CoV-2 specific CD8+ T cell response with immunodominant features

    Article • Nature Communications, May 2021, Springer Science + Business Media

    MD Massimo Girardis

  69. Never Give Up: Lesson learned from a severe COVID-19 patient

    Article • Pulmonology, May 2021, Taylor & Francis

    MD Massimo Girardis, Professor Enrico M. Clini

  70. Prone position in intubated, mechanically ventilated patients with COVID-19: a multi-centric study of more than 1000 patients

    Article • Critical Care, April 2021, Springer Science + Business Media

    MD Massimo Girardis

  71. An update on levosimendan in acute cardiac care: applications and recommendations for optimal efficacy and safety

    Article • Expert Review of Cardiovascular Therapy, April 2021, Taylor & Francis

    MD Massimo Girardis

  72. Bridging animal and clinical research during SARS-CoV-2 pandemic: A new-old challenge

    Article • EBioMedicine, April 2021, Elsevier

    MD Massimo Girardis

  73. The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Roberta Russo, MD Massimo Girardis

  74. Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study

    Article • eLife, March 2021, eLife

    Roberta Russo, MD Massimo Girardis

  75. Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males

    Article • EBioMedicine, March 2021, Elsevier

    Roberta Russo, MD Massimo Girardis

  76. Development and validation of a prediction model for tocilizumab failure in hospitalized patients with SARS-CoV-2 infection

    Article • PLOS One, February 2021, PLOS

    MD Massimo Girardis, Professor Enrico M. Clini

  77. Adjunctive Immunotherapy With Polyclonal Ig-M Enriched Immunoglobulins for Septic Shock: From Bench to Bedside. The Rationale for a Personalized Treatment Protocol

    Article • Frontiers in Medicine, February 2021, Frontiers

    MD Massimo Girardis

  78. Incidence and Prognosis of Ventilator-Associated Pneumonia in Critically Ill Patients with COVID-19: A Multicenter Study

    Article • Journal of Clinical Medicine, February 2021, MDPI AG

    Professor Stefano Di Bella, MD Massimo Girardis

  79. Adjunctive IgM-enriched immunoglobulin therapy with a personalised dose based on serum IgM-titres versus standard dose in the treatment of septic shock: a randomised controlled trial (IgM-fat trial)

    Article • BMJ Open, February 2021, BMJ

    MD Massimo Girardis

  80. Post-Mendelian genetic model in COVID-19

    Article • January 2021, Cold Spring Harbor Laboratory Press

    Roberta Russo, MD Massimo Girardis

  81. Employing a systematic approach to biobanking and analyzing clinical and genetic data for advancing COVID-19 research

    Article • European Journal of Human Genetics, January 2021, Springer Science + Business Media

    Roberta Russo, MD Massimo Girardis

  82. Hypokalemia in Patients with COVID-19

    Article • Clinical and Experimental Nephrology, January 2021, Springer Science + Business Media

    MD Massimo Girardis

  83. Cluster analysis identifies patients at risk of catheter-associated urinary tract infections in intensive care units: findings from the SPIN-UTI Network

    Article • Journal of Hospital Infection, January 2021, Elsevier

    MD Massimo Girardis

  84. Genetic mechanisms of critical illness in Covid-19

    Article • Nature, December 2020, Springer Science + Business Media

    Hugh Montgomery, Roberta Russo, MD Massimo Girardis

  85. Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study

    Article • The Lancet Respiratory Medicine, December 2020, Elsevier

    MD Massimo Girardis

  86. Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Roberta Russo, MD Massimo Girardis

  87. Clinical and molecular characterization of COVID-19 hospitalized patients

    Article • PLOS One, November 2020, PLOS

    MD Massimo Girardis

  88. Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia—Challenges, strengths, and opportunities in a global health emergency

    Article • PLOS One, November 2020, PLOS

    MD Massimo Girardis, Professor Enrico M. Clini

  89. Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in males

    Article • November 2020, Cold Spring Harbor Laboratory Press

    Roberta Russo, MD Massimo Girardis

  90. Altered bioenergetics and mitochondrial dysfunction of monocytes in patients with COVID‐19 pneumonia

    Article • EMBO Molecular Medicine, November 2020, Springer Science + Business Media

    MD Massimo Girardis

  91. Testicular pain as an unusual presentation of COVID-19: a brief review of SARS-CoV-2 and the testis

    Article • Reproductive BioMedicine Online, November 2020, Elsevier

    MD Massimo Girardis

  92. Use of critical care resources during the first 2 weeks (February 24–March 8, 2020) of the Covid-19 outbreak in Italy

    Article • Annals of Intensive Care, October 2020, Springer Science + Business Media

    MD Massimo Girardis

  93. Best-practice IgM- and IgA-enriched immunoglobulin use in patients with sepsis

    Article • Annals of Intensive Care, October 2020, Springer Science + Business Media

    MD Massimo Girardis

  94. Adjunctive therapy with vitamin c and thiamine in patients treated with steroids for refractory septic shock: A propensity matched before-after, case-control study

    Article • Journal of Critical Care, October 2020, Elsevier

    MD Massimo Girardis

  95. COVID-19-associated vasculitis and thrombotic complications: from pathological findings to multidisciplinary discussion

    Article • Rheumatology, September 2020, Oxford University Press (OUP)

    MD Massimo Girardis

  96. The predictive value of fruit juice in the esophagus-pleural fistula

    Article • Italian Journal of Medicine, September 2020, PAGEPress Publications

    MD Massimo Girardis

  97. Two Fatal Cases of Acute Liver Failure Due to HSV-1 Infection in COVID-19 Patients Following Immunomodulatory Therapies

    Article • Clinical Infectious Diseases, August 2020, Oxford University Press (OUP)

    MD Massimo Girardis, Professor Enrico M. Clini

  98. Multi-centre, three arm, randomized controlled trial on the use of methylprednisolone and unfractionated heparin in critically ill ventilated patients with pneumonia from SARS-CoV-2 infection: A structured summary of a study protocol for a randomised c...

    Article • Trials, August 2020, Springer Science + Business Media

    MD Massimo Girardis, Prof Gilda Cinnella

  99. Early Inspiratory Effort Assessment by Esophageal Manometry Predicts Noninvasive Ventilation Outcome in De Novo Respiratory Failure. A Pilot Study

    Article • American Journal of Respiratory and Critical Care Medicine, August 2020, American Thoracic Society

    MD Massimo Girardis, Professor Enrico M. Clini

  100. Expansion of plasmablasts and loss of memory B cells in peripheral blood from COVID‐19 patients with pneumonia

    Article • European Journal of Immunology, August 2020, Wiley

    MD Massimo Girardis

  101. Tocilizumab in patients with severe COVID-19: a retrospective cohort study

    Article • The Lancet Rheumatology, August 2020, Elsevier

    MD Massimo Girardis, Professor Enrico M. Clini

  102. Employing a Systematic Approach to Biobanking and Analyzing Clinical and Genetic Data for Advancing COVID-19 Research

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Roberta Russo, MD Massimo Girardis

  103. Guide-wire replacement of a mini-midline catheter with a central venous catheter: A retrospective study on 63 cases

    Article • The Journal of Vascular Access, July 2020, SAGE Publications

    MD Massimo Girardis

  104. ACE2 gene variants may underlie interindividual variability and susceptibility to COVID-19 in the Italian population

    Article • European Journal of Human Genetics, July 2020, Springer Science + Business Media

    Roberta Russo, MD Massimo Girardis

  105. Marked T cell activation, senescence, exhaustion and skewing towards TH17 in patients with COVID-19 pneumonia

    Article • Nature Communications, July 2020, Springer Science + Business Media

    MD Massimo Girardis, Professor Enrico M. Clini

  106. Levosimendan Efficacy and Safety: 20 Years of SIMDAX in Clinical Use

    Article • Journal of Cardiovascular Pharmacology, July 2020, Wolters Kluwer Health

    MD Massimo Girardis

  107. Incidence, Risk Factors and Mortality Outcome in Patients with Acute Kidney Injury in COVID-19: A Single-Center Observational Study

    Article • June 2020, Cold Spring Harbor Laboratory Press

    MD Massimo Girardis

  108. A case of splenic artery pseudoaneurysm rupture in a bulimic patient with gastric ulcer

    Article • Italian Journal of Medicine, June 2020, PAGEPress Publications

    MD Massimo Girardis

  109. Reply to “Indications and timing for tracheostomy in patients with SARS CoV2‐related” by Ferri et al.

    Article • European Archives of Oto-Rhino-Laryngology, June 2020, Springer Science + Business Media

    MD Massimo Girardis

  110. Hypokalemia in Patients with COVID-19

    Article • June 2020, Cold Spring Harbor Laboratory Press

    MD Massimo Girardis

  111. Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study

    Article • Intensive Care Medicine, June 2020, Springer Science + Business Media

    Dr Marlies Ostermann, MD Massimo Girardis

  112. Machine learning in predicting respiratory failure in patients with COVID-19 pneumonia - challenges, strengths, and opportunities in a global health emergency

    Article • June 2020, Cold Spring Harbor Laboratory Press

    MD Massimo Girardis

  113. Clinical and molecular characterization of COVID-19 hospitalized patients

    Article • May 2020, Cold Spring Harbor Laboratory Press

    MD Massimo Girardis

  114. Increased Plasma Levels of Mitochondrial DNA and Normal Inflammasome Gene Expression in Monocytes Characterize Patients With Septic Shock Due to Multidrug Resistant Bacteria

    Article • Frontiers in Immunology, May 2020, Frontiers

    MD Massimo Girardis

  115. The clinical relevance of oliguria in the critically ill patient: analysis of a large observational database

    Article • Critical Care, April 2020, Springer Science + Business Media

    Dr Katarzyna L Kotfis, S Vadi, MD Massimo Girardis, Dr. Pablo Monedero

  116. Tracheostomy in the COVID-19 pandemic

    Article • European Archives of Oto-Rhino-Laryngology, April 2020, Springer Science + Business Media

    MD Massimo Girardis

  117. Ceftolozane/Tazobactam for Treatment of Severe ESBL-Producing Enterobacterales Infections: A Multicenter Nationwide Clinical Experience (CEFTABUSE II Study)

    Article • Open Forum Infectious Diseases, April 2020, Oxford University Press (OUP)

    MD Massimo Girardis

  118. Handling and Processing of Blood Specimens from Patients with COVID‐19 for Safe Studies on Cell Phenotype and Cytokine Storm

    Article • Cytometry Part A, April 2020, Wiley

    MD Massimo Girardis, Professor Enrico M. Clini

  119. SARS‐CoV‐2, the Virus that Causes COVID‐19: Cytometry and the New Challenge for Global Health

    Article • Cytometry Part A, March 2020, Wiley

    MD Massimo Girardis

  120. Case report of a patient who survived after cardiac arrest and cardiogenic shock by anaphylactic reaction to gadolinium during magnetic resonance imaging

    Article • Radiology Case Reports, March 2020, Elsevier

    MD Massimo Girardis

  121. Shorter Androgen Receptor PolyQ Alleles Protect Against Life-Threatening COVID-19 Disease in Males

    Article • SSRN Electronic Journal, January 2020, Elsevier

    Roberta Russo, MD Massimo Girardis

  122. OUP accepted manuscript

    Article • Clinical Kidney Journal, January 2020, Oxford University Press (OUP)

    MD Massimo Girardis

  123. Surfactant replacement might help recovery of low-compliance lung in severe COVID-19 pneumonia

    Article • Therapeutic Advances in Respiratory Disease, January 2020, SAGE Publications

    MD Massimo Girardis, Professor Enrico M. Clini

  124. Current gaps in sepsis immunology: new opportunities for translational research

    Article • The Lancet Infectious Diseases, December 2019, Elsevier

    MD Massimo Girardis

  125. University of Modena Experience With Liver Grafts From Donation After Circulatory Death: What Really Matters in Organ Selection?

    Article • Transplantation Proceedings, November 2019, Elsevier

    MD Massimo Girardis

  126. Epidemiology of intra-abdominal infection and sepsis in critically ill patients: “AbSeS”, a multinational observational cohort study and ESICM Trials Group Project

    Article • Intensive Care Medicine, October 2019, Springer Science + Business Media

    Dr Marlies Ostermann, Associate Professor VIncenzo Pota, MD Massimo Girardis, Prof Gilda Cinnella

  127. Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project

    Article • Critical Care, June 2019, Springer Science + Business Media

    MD Massimo Girardis

  128. What’s new in oxygen therapy?

    Article • Intensive Care Medicine, May 2019, Springer Science + Business Media

    MD Massimo Girardis

  129. Oxygen: a powerful drug to handle with care

    Article • Journal of Thoracic Disease, March 2019, AME Publishing Company

    MD Massimo Girardis

  130. Cytoreductive surgery and HIPEC in a 14 years old patient with peritoneal recurrence of adenocarcinoma of the right colon

    Article • International Journal of Surgery Case Reports, January 2019, Elsevier

    MD Massimo Girardis

  131. Use of Levosimendan in Intensive Care Unit Settings

    Article • Journal of Cardiovascular Pharmacology, January 2019, Wolters Kluwer Health

    MD Massimo Girardis

  132. Landiolol in patients with septic shock resident in an intensive care unit (LANDI-SEP): study protocol for a randomized controlled trial

    Article • Trials, November 2018, Springer Science + Business Media

    MD Massimo Girardis

  133. JLB: a new long-cannula venous catheter

    Article • The Journal of Vascular Access, September 2018, SAGE Publications

    Mirco Ravazzini, MD Massimo Girardis

  134. Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature

    Article • Case Reports in Critical Care, August 2018, Hindawi Publishing Corporation

    MD Massimo Girardis

  135. Real-time monitoring of Pseudomonas aeruginosa biofilm formation on endotracheal tubes in vitro

    Article • BMC Microbiology, August 2018, Springer Science + Business Media

    MD Massimo Girardis

  136. Experienced Use of Dexmedetomidine in the Intensive Care Unit: A Report of a Structured Consensus

    Article • July 2018, AVES Publishing Co.

    MD Massimo Girardis

  137. Prognostic Potential of the Panfungal Marker (1 → 3)-β-d-Glucan in Invasive Mycoses Patients

    Article • Mycopathologia, July 2018, Springer Science + Business Media

    MD Massimo Girardis

  138. Procalcitonin-guided antibiotic therapy: an expert consensus

    Article • Clinical Chemistry and Laboratory Medicine (CCLM), June 2018, De Gruyter

    MD Massimo Girardis

  139. Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

    Article • Intensive Care Medicine, February 2018, Springer Science + Business Media

    Dr. Pablo Monedero, Dr Katarzyna L Kotfis, MD Massimo Girardis, Eric Hoste

  140. Oxygen in the critically ill

    Article • Current Opinion in Anaesthesiology, January 2018, Wolters Kluwer Health

    MD Massimo Girardis

  141. The prognostic importance of chronic end-stage diseases in geriatric patients admitted to 163 Italian ICUs

    Article • Minerva Anestesiologica, December 2017, Edizioni Minerva Medica

    MD Massimo Girardis, Associate Professor VIncenzo Pota

  142. Correction to: The Intensive Care Global Study on Severe Acute Respiratory Infection (IC-GLOSSARI): a multicenter, multinational, 14-day inception cohort study

    Article • Intensive Care Medicine, November 2017, Springer Science + Business Media

    Dr. Pablo Monedero, Dr Andrea Cortegiani, Dr Marlies Ostermann, MD Massimo Girardis, Associate Professor VIncenzo Pota

  143. A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway

    Article • Surgical Infections, November 2017, Mary Ann Liebert Inc

    Dr Timothy Craig Hardcastle, Prof. Majdi Al-Hasan, MD Massimo Girardis, Francesco Di Marzo, Dr Salomone Di Saverio

  144. Common Practice and Guidelines for Sedation in Critically Ill Patients

    Article • October 2017, Springer Science + Business Media

    MD Massimo Girardis

  145. Randomized, multicenter trial of lateral Trendelenburg versus semirecumbent body position for the prevention of ventilator-associated pneumonia

    Article • Intensive Care Medicine, June 2017, Springer Science + Business Media

    MD Massimo Girardis

  146. Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference

    Article • World Journal of Emergency Surgery, May 2017, Springer Science + Business Media

    MD Massimo Girardis

  147. Effects of short-term hyperoxia on erythropoietin levels and microcirculation in critically Ill patients: a prospective observational pilot study

    Article • BMC Anesthesiology, March 2017, Springer Science + Business Media

    MD Massimo Girardis

  148. Injury-induced immunosuppression: are we finally on the right track?

    Article • Minerva Anestesiologica, March 2017, Edizioni Minerva Medica

    MD Massimo Girardis

  149. Oxygen Supplementation Among Patients in the Intensive Care Unit

    Article • JAMA, February 2017, American Medical Association (AMA)

    MD Massimo Girardis

  150. Mortality in Patients With Septic Shock by Multidrug Resistant Bacteria

    Article • Journal of Intensive Care Medicine, January 2017, SAGE Publications

    MD Massimo Girardis

  151. Impact of Pre-Analytical Time on the Recovery of Pathogens from Blood Cultures: Results from a Large Retrospective Survey

    Article • PLOS One, January 2017, PLOS

    MD Massimo Girardis

  152. The Role of Adjunctive Therapies in Septic Shock by Gram Negative MDR/XDR Infections

    Article • Canadian Journal of Infectious Diseases and Medical Microbiology, January 2017, Hindawi Publishing Corporation

    MD Massimo Girardis

  153. Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit

    Article • JAMA, October 2016, American Medical Association (AMA)

    MD Massimo Girardis

  154. Dexmedetomidine for agitated delirium in intensive care unit intubated patients

    Article • Journal of Thoracic Disease, September 2016, AME Publishing Company

    MD Massimo Girardis

  155. Evaluation of serum (1 → 3)-β-d-glucan clinical performance: kinetic assessment, comparison with galactomannan and evaluation of confounding factors

    Article • Infection, October 2015, Springer Science + Business Media

    MD Massimo Girardis

  156. A one-year prospective study of refractory status epilepticus in Modena, Italy

    Article • Epilepsy & Behavior, August 2015, Elsevier

    MD Massimo Girardis

  157. The Surviving Sepsis Campaign bundles and outcome: results from the International Multicentre Prevalence Study on Sepsis (the IMPreSS study)

    Article • Intensive Care Medicine, June 2015, Springer Science + Business Media

    MD Massimo Girardis

  158. A challenging case of pregnancy with placenta accreta and very rare irregular antibodies versus Cromer blood group system: a case report

    Article • Journal of Medical Case Reports, May 2015, Springer Science + Business Media

    MD Massimo Girardis

  159. Effect of Performance Improvement Programs on Compliance with Sepsis Bundles and Mortality: A Systematic Review and Meta-Analysis of Observational Studies

    Article • PLOS One, May 2015, PLOS

    MD Massimo Girardis

  160. Arterial hyperoxia and mortality in critically ill patients: a systematic review and meta-analysis

    Article • Critical Care, December 2014, Springer Science + Business Media

    MD Massimo Girardis

  161. Trends in ventilator-associated pneumonia: Impact of a ventilator care bundle in an Italian tertiary care hospital intensive care unit

    Article • American Journal of Infection Control, December 2014, Elsevier

    MD Massimo Girardis

  162. World Society of Emergency Surgery (WSES) guidelines for management of skin and soft tissue infections

    Article • World Journal of Emergency Surgery, November 2014, Springer Science + Business Media

    MD Massimo Girardis

  163. Wernicke’s encephalopathy in a malnourished surgical patient: a difficult diagnosis

    Article • BMC Research Notes, October 2014, Springer Science + Business Media

    MD Massimo Girardis

  164. Early therapy with IgM-enriched polyclonal immunoglobulin in patients with septic shock

    Article • Intensive Care Medicine, September 2014, Springer Science + Business Media

    MD Massimo Girardis

  165. Clinical performance of a commercial real-time PCR assay for Aspergillus DNA detection in serum samples from high-risk patients: comparison with a galactomannan enzyme immunoassay

    Article • European Journal of Clinical Microbiology & Infectious Diseases, August 2014, Springer Science + Business Media

    MD Massimo Girardis

  166. Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit

    Article • The Lancet Respiratory Medicine, May 2014, Elsevier

    Dr. Pablo Monedero, Dr Katarzyna L Kotfis, MD Massimo Girardis, Dr Nick Fletcher

  167. Erratum to: An Italian consensus for invasive candidiasis management (ITALIC)

    Article • Infection, January 2014, Springer Science + Business Media

    MD Massimo Girardis

  168. Loss of Self-Regulation in Interstitial Fluid Dynamics of Septic Patients, and Oedema Development Patterns

    Article • November 2013, Springer Science + Business Media

    MD Massimo Girardis

  169. Immunoglobulin as Adjunctive Therapy in Sepsis

    Article • November 2013, Springer Science + Business Media

    MD Massimo Girardis

  170. Effect of Heart Rate Control With Esmolol on Hemodynamic and Clinical Outcomes in Patients With Septic Shock

    Article • JAMA, October 2013, American Medical Association (AMA)

    MD Massimo Girardis

  171. A Janus role for MerTK in the outcome of septic shock

    Article • Intensive Care Medicine, October 2013, Springer Science + Business Media

    MD Massimo Girardis

  172. Endotoxin activity levels as a prediction tool for risk of deterioration in patients with sepsis not admitted to the intensive care unit: A pilot observational study

    Article • Journal of Critical Care, October 2013, Elsevier

    MD Massimo Girardis

  173. The aPC treatment improves microcirculation in severe sepsis/septic shock syndrome

    Article • BMC Anesthesiology, September 2013, Springer Science + Business Media

    MD Massimo Girardis

  174. Characterization of Specific Immune Responses to Different Aspergillus Antigens during the Course of Invasive Aspergillosis in Hematologic Patients

    Article • PLOS One, September 2013, PLOS

    MD Massimo Girardis

  175. Characteristics and outcome predictors of patients involved in an outbreak of Burkholderia cepacia complex

    Article • Journal of Hospital Infection, September 2013, Elsevier

    MD Massimo Girardis

  176. Hemostasis in acute liver and kidney failure: nothing is as it seems

    Article • Kidney International, July 2013, Elsevier

    MD Massimo Girardis

  177. Aggressive versus conservative initiation of antibiotics

    Article • The Lancet Infectious Diseases, May 2013, Elsevier

    MD Massimo Girardis

  178. Effectiveness of sepsis bundle application in cirrhotic patients with septic shock: a single-center experience

    Article • Journal of Critical Care, April 2013, Elsevier

    MD Massimo Girardis

  179. Early alterations of B cells in patients with septic shock: another piece in the complex puzzle of the immune response in sepsis

    Article • Critical Care, January 2013, Springer Science + Business Media

    MD Massimo Girardis

  180. Successful liver transplantation in a patient with splanchnic vein thrombosis and pulmonary embolism due to polycythemia vera with Jak2v617f mutation and heparin-induced thrombocytopenia

    Article • Journal of Thrombosis and Thrombolysis, January 2013, Springer Science + Business Media

    MD Massimo Girardis

  181. Levosimendan in a case of severe peri-myocarditis associated with influenza A/H1N1 virus

    Article • British Journal of Anaesthesia, December 2012, Elsevier

    MD Massimo Girardis

  182. Hospital staff education on severe sepsis/septic shock and hospital mortality: an original hypothesis

    Article • BMC Anesthesiology, November 2012, Springer Science + Business Media

    MD Massimo Girardis

  183. A new technique for percutaneous dilatational tracheostomy (G-Trach): preliminary experience in pigs

    Article • Anaesthesia, June 2012, Wiley

    MD Massimo Girardis

  184. Abdominal Compartment Syndrome and Fluid Replacement: A Dog That Bites Its Own Tail?

    Article • January 2012, Springer Science + Business Media

    MD Massimo Girardis

  185. Erratum

    Article • Transplantation Proceedings, January 2012, Elsevier

    MD Massimo Girardis

  186. PSP/reg: a new stone in sepsis biomarkers?

    Article • Critical Care, January 2012, Springer Science + Business Media

    MD Massimo Girardis

  187. Massive bleeding: Are we doing our best?

    Article • Transfusion and Apheresis Science, December 2011, Elsevier

    MD Massimo Girardis

  188. Acute Renal Failure and Renal Replacement Therapy in the Postoperative Period of Orthotopic Liver Transplant Patients Versus Nonelective Abdominal Surgery Patients

    Article • Transplantation Proceedings, May 2011, Elsevier

    MD Massimo Girardis

  189. Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection

    Article • Intensive Care Medicine, November 2010, Springer Science + Business Media

    Dr. Pablo Monedero, MD Massimo Girardis

  190. Posttraumatic massive bleeding: a challenging multidisciplinary task

    Article • Internal and Emergency Medicine, May 2010, Springer Science + Business Media

    MD Massimo Girardis

  191. Levosimendan in Cardiac Failure After Subarachnoid Hemorrhage

    Article • Journal of Trauma and Acute Care Surgery, May 2010, Wolters Kluwer Health

    MD Massimo Girardis

  192. Two-stage liver transplantation: an effective procedure in urgent conditions

    Article • Clinical Transplantation, January 2010, Wiley

    MD Massimo Girardis

  193. Perioperative Red Blood Cell Transfusion and Outcome in Stable Patients after Elective Major Vascular Surgery

    Article • European Journal of Vascular and Endovascular Surgery, March 2009, Elsevier

    MD Massimo Girardis

  194. Effects on management and outcome of severe sepsis and septic shock patients admitted to the intensive care unit after implementation of a sepsis program: a pilot study

    Article • Critical Care, January 2009, Springer Science + Business Media

    MD Massimo Girardis

  195. Use of activated protein c in liver transplantation patients with septic shock

    Article • Liver Transplantation, November 2008, Wiley

    MD Massimo Girardis

  196. Incidence and Clinical Outcomes of Ventilator-Associated Pneumonia in Liver Transplant and Non-Liver Transplant Surgical Patients

    Article • Transplantation Proceedings, July 2008, Elsevier

    MD Massimo Girardis

  197. Recombinant Activated Factor VII in Critical Bleeding After Orthotopic Liver Transplantation

    Article • Transplantation Proceedings, July 2008, Elsevier

    MD Massimo Girardis

  198. Strategies to Control Massive Abdominal Bleeding

    Article • Transplantation Proceedings, May 2008, Elsevier

    MD Massimo Girardis

  199. A modified goal-directed protocol improves clinical outcome in intensive care unit patients with septic shock patients

    Article • Shock, December 2007, Wolters Kluwer Health

    MD Massimo Girardis

  200. Liver transplantation in HIV patients

    Article • Digestive and Liver Disease, October 2007, Elsevier

    MD Massimo Girardis

  201. Peri-operative respiratory failure in a cirrhotic patient: a misleading diagnosis

    Article • Anaesthesia, September 2007, Wiley

    MD Massimo Girardis

  202. Gram-Positive Bloodstream Infections in Liver Transplant Recipients: Incidence, Risk Factors, and Impact on Survival

    Article • Transplantation Proceedings, July 2007, Elsevier

    MD Massimo Girardis

  203. Intracerebral haemorrhage: an often neglected medical emergency

    Article • Internal and Emergency Medicine, March 2007, Springer Science + Business Media

    MD Massimo Girardis

  204. Living Donor Liver Transplantation and Management of Portal Venous Pressure

    Article • Transplantation Proceedings, May 2006, Elsevier

    MD Massimo Girardis

  205. Intra-abdominal Hypertension in Nonelective Surgery: A Preliminary Report

    Article • Transplantation Proceedings, April 2006, Elsevier

    MD Massimo Girardis

  206. Posttransplant Cerebral Hemorrhage in a Patient with Familial Amyloidotic Polyneuropathy

    Article • Transplantation, January 2006, Wolters Kluwer Health

    MD Massimo Girardis

  207. Rectal amputation sparing by haemostatic therapy with recombinant factor VIIa in a patient with cytomegalovirus–related colitis

    Article • Thrombosis and Haemostasis, January 2006, Thieme Publishing Group

    MD Massimo Girardis

  208. More on: platelet count and the Use of Recombinant Factor VIIa for the treatment of Bleeding Complications after Hematopoietic Stem Cell Transplantation

    Article • Journal of Thrombosis and Haemostasis, December 2005, Wiley

    MD Massimo Girardis

  209. Comment on: ?Hemodynamic response to coupled plasmafiltration-adsorption in human septic shock? by Formica et al.

    Article • Intensive Care Medicine, January 2004, Springer Science + Business Media

    MD Massimo Girardis

  210. Muscle perfusion and oxygen consumption by near-infrared spectroscopy in septic-shock and non-septic-shock patients

    Article • Intensive Care Medicine, July 2003, Springer Science + Business Media

    MD Massimo Girardis

  211. Extravascular lung water and intravascular volume monitoring

    Article • Intensive Care Medicine, December 2002, Springer Science + Business Media

    MD Massimo Girardis

  212. Pain management after small bowel/multivisceral transplantation

    Article • Transplantation Proceedings, May 2002, Elsevier

    MD Massimo Girardis

  213. Prevention of post-herpetic neuralgia: acyclovir and prednisolone versus epidural local anesthetic and methylprednisolone

    Article • Acta Anaesthesiologica Scandinavica, September 2000, Wiley

    MD Massimo Girardis

  214. Oxygen cost of dynamic leg exercise on a cycle ergometer: effects of gravity acceleration

    Article • Acta Physiologica Scandinavica, July 1999, Wiley

    MD Massimo Girardis

  215. Severe hypoxemia and pulmonary hypertension during orthotopic liver transplantation: a successful use of inhaled nitric oxide

    Article • Intensive Care Medicine, June 1999, Springer Science + Business Media

    MD Massimo Girardis

  216. Effects of prolonged bed rest on cardiovascular oxygen transport during submaximal exercise in humans

    Article • European Journal of Applied Physiology and Occupational Physiology, September 1998, Springer Science + Business Media

    MD Massimo Girardis

  217. Effects of elastic recoil on maximal explosive power of the lower limbs

    Article • European Journal of Applied Physiology and Occupational Physiology, April 1997, Springer Science + Business Media

    MD Massimo Girardis, MD Carlo Capelli

  218. The Effect of Laparoscopic Cholecystectomy on Cardiovascular Function and Pulmonary Gas Exchange

    Article • Anesthesia & Analgesia, March 1997, Wolters Kluwer Health

    MD Massimo Girardis

  219. The Effect of Laparoscopic Cholecystectomy on Cardiovascular Function and Pulmonary Gas Exchange

    Article • Anesthesia & Analgesia, July 1996, Wolters Kluwer Health

    MD Massimo Girardis

  220. Oxygen cost of internal work during cycling

    Article • European Journal of Applied Physiology and Occupational Physiology, January 1995, Springer Science + Business Media

    Dr Maria Pia Francescato, MD Massimo Girardis

  221. Noninvasive assessment of cardiac output from arterial pressure profiles during exercise

    Article • European Journal of Applied Physiology and Occupational Physiology, January 1995, Springer Science + Business Media

    MD Massimo Girardis

  222. Assessment of cardiac output from noninvasive determination of arterial pressure profile in subjects at rest

    Article • European Journal of Applied Physiology and Occupational Physiology, May 1994, Springer Science + Business Media

    MD Massimo Girardis, MD Carlo Capelli

  223. Effects of prolonged cycle ergometer exercise on maximal muscle power and oxygen uptake in humans

    Article • European Journal of Applied Physiology and Occupational Physiology, March 1993, Springer Science + Business Media

    MD Massimo Girardis, MD Carlo Capelli

  224. Severe bleeding in critical care

    Article • Springer Science + Business Media

    MD Massimo Girardis

  225. New frontiers in critical bleeding

    Article • Springer Science + Business Media

    MD Massimo Girardis