All Stories

  1. Uric acid analogue as a possible xenobiotic marker of uric acid transporter Urat1 in rats

    Article • Drug Metabolism and Pharmacokinetics, December 2018, Elsevier

    Takeo Nakanishi

  2. Re-secretion of PGE2 by the prostaglandin transporter (OATP2A1/SLCO2A1) in alveolar epithelial cells

    Article • Journal of Pharmacology and Experimental Therapeutics, November 2018, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  3. Apple-Derived Nanoparticles Modulate Expression of Organic-Anion-Transporting Polypeptide (OATP) 2B1 in Caco-2 Cells

    Article • Molecular Pharmaceutics, October 2018, American Chemical Society (ACS)

    Takeo Nakanishi

  4. Effect of tyrosine kinase inhibitors on renal handling of creatinine by MATE1

    Article • Scientific Reports, June 2018, Springer Science + Business Media

    Takeo Nakanishi

  5. Prostaglandin Transporter OATP2A1/SLCO2A1 Is Essential for Body Temperature Regulation during Fever

    Article • Journal of Neuroscience, May 2018, Society for Neuroscience

    Takeo Nakanishi

  6. Contribution of equilibrative nucleoside transporters 1 and 2 to gemcitabine uptake in pancreatic cancer cells

    Article • Biopharmaceutics & Drug Disposition, April 2018, Wiley

    Takeo Nakanishi

  7. Impact of Breast Cancer Resistance Protein Expression on the In Vitro Efficacy of Anticancer Drugs in Pancreatic Cancer Cell Lines

    Article • Drug Metabolism and Disposition, December 2017, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  8. Contribution of equilibrative nucleoside transporter(s) to intestinal basolateral and apical transports of anticancer trifluridine

    Article • Biopharmaceutics & Drug Disposition, December 2017, Wiley

    Takeo Nakanishi

  9. Roles of Organic Anion Transporting Polypeptide 2A1 (OATP2A1/SLCO2A1) in Regulating the Pathophysiological Actions of Prostaglandins

    Article • The AAPS Journal, December 2017, American Association of Pharmaceutical Scientists (AAPS)

    Takeo Nakanishi

  10. A novel role for OATP2A1/SLCO2A1 in a murine model of colon cancer

    Article • Scientific Reports, November 2017, Springer Science + Business Media

    Takeo Nakanishi, Masanobu Oshima

  11. Usefulness of kidney slices for functional analysis of apical reabsorptive transporters

    Article • Scientific Reports, October 2017, Springer Science + Business Media

    Takeo Nakanishi

  12. Association of miR-145 With Statin-Induced Skeletal Muscle Toxicity in Human Rhabdomyosarcoma RD Cells

    Article • Journal of Pharmaceutical Sciences, September 2017, Elsevier

    Takeo Nakanishi

  13. Current Progress Toward a Better Understanding of Drug Disposition Within the Lungs: Summary Proceedings of the First Workshop on Drug Transporters in the Lungs

    Article • Journal of Pharmaceutical Sciences, September 2017, Elsevier

    Takeo Nakanishi

  14. Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban

    Article • Journal of Pharmaceutical Sciences, September 2017, Elsevier

    Takeo Nakanishi

  15. Impact of FDA-Approved Drugs on the Prostaglandin Transporter OATP2A1/ SLCO2A1

    Article • Journal of Pharmaceutical Sciences, September 2017, Elsevier

    Takeo Nakanishi

  16. Co-localization of microsomal prostaglandin E synthase-1 with cyclooxygenase-1 in layer II of murine placental syncytiotrophoblasts

    Article • Placenta, May 2017, Elsevier

    Takeo Nakanishi

  17. Comparative Evaluation of Dehydroepiandrosterone Sulfate Potential to Predict Hepatic Organic Anion Transporting Polypeptide Transporter-Based Drug-Drug Interactions

    Article • Drug Metabolism and Disposition, December 2016, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  18. Methods to Discover Alternative Promoter Usage and Transcriptional Regulation of Murine Bcrp1

    Article • Journal of Visualized Experiments, May 2016, MyJove Corporation

    Takeo Nakanishi

  19. Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue

    Article • Journal of Pharmaceutical Sciences, February 2016, Elsevier

    Takeo Nakanishi

  20. Role of OATP2A1 in PGE2 secretion from human colorectal cancer cells via exocytosis in response to oxidative stress

    Article • Experimental Cell Research, February 2016, Elsevier

    Takeo Nakanishi

  21. Molecular localization and characterization of multiple binding sites of organic anion transporting polypeptide 2B1 (OATP2B1) as the mechanism for substrate and modulator dependent drug–drug interaction

    Article • MedChemComm, January 2016, Royal Society of Chemistry

    Takeo Nakanishi

  22. Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3

    Article • Prostaglandins & Other Lipid Mediators, January 2016, Elsevier

    Takeo Nakanishi

  23. OATP2A1/SLCO2A1-mediated prostaglandin E2 loading into intracellular acidic compartments of macrophages contributes to exocytotic secretion

    Article • Biochemical Pharmacology, December 2015, Elsevier

    Takeo Nakanishi

  24. Organic Anion Transporting Polypeptide (OATP)2B1 Contributes to Gastrointestinal Toxicity of Anticancer Drug SN-38, Active Metabolite of Irinotecan Hydrochloride

    Article • Drug Metabolism and Disposition, November 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  25. [14C]Fluciclovine (alias anti-[14C]FACBC) uptake and ASCT2 expression in castration-resistant prostate cancer cells

    Article • Nuclear Medicine and Biology, November 2015, Elsevier

    Takeo Nakanishi

  26. Analysis of the Metabolic Pathway of Bosentan and of the Cytotoxicity of Bosentan Metabolites Based on a Quantitative Modeling of Metabolism and Transport in Sandwich-Cultured Human Hepatocytes

    Article • Drug Metabolism and Disposition, October 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  27. Local Drug-Drug Interaction of Donepezil with Cilostazol at Breast Cancer Resistance Protein (ABCG2) Increases Drug Accumulation in Heart

    Article • Drug Metabolism and Disposition, October 2015, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  28. Involvement of Concentrative Nucleoside Transporter 1 in Intestinal Absorption of Trifluridine Using Human Small Intestinal Epithelial Cells

    Article • Journal of Pharmaceutical Sciences, September 2015, Elsevier

    Takeo Nakanishi

  29. Kinetic Evaluation of Determinant Factors for Cellular Accumulation of Protoporphyrin IX Induced by External 5-Aminolevulinic Acid for Photodynamic Cancer Therapy

    Article • Journal of Pharmaceutical Sciences, September 2015, Elsevier

    Takeo Nakanishi

  30. Saturable Hepatic Extraction of Gemcitabine Involves Biphasic Uptake Mediated by Nucleoside Transporters Equilibrative Nucleoside Transporter 1 and 2

    Article • Journal of Pharmaceutical Sciences, September 2015, Elsevier

    Takeo Nakanishi

  31. Corrigendum to “Kinetic analyses of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2” (Nucl. Med. Biol. 2013;40:670–675)

    Article • Nuclear Medicine and Biology, May 2015, Elsevier

    Takeo Nakanishi

  32. Modeling approach for multiple transporters-mediated drug–drug interactions in sandwich-cultured human hepatocytes: Effect of cyclosporin A on hepatic disposition of mycophenolic acid phenyl-glucuronide

    Article • Drug Metabolism and Pharmacokinetics, April 2015, Elsevier

    Takeo Nakanishi

  33. Organic anion transporting polypeptide 2B1 expression correlates with uptake of estrone-3-sulfate and cell proliferation in estrogen receptor-positive breast cancer cells

    Article • Drug Metabolism and Pharmacokinetics, April 2015, Elsevier

    Takeo Nakanishi

  34. Functional cyclic AMP response element in the breast cancer resistance protein (BCRP/ABCG2) promoter modulates epidermal growth factor receptor pathway- or androgen withdrawal-mediated BCRP/ABCG2 transcription in human cancer cells

    Article • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, March 2015, Elsevier

    Takeo Nakanishi

  35. In-vitro evidence of enhanced breast cancer resistance protein-mediated intestinal urate secretion by uremic toxins in Caco-2 cells

    Article • Journal of Pharmacy and Pharmacology, December 2014, Wiley

    Takeo Nakanishi

  36. Putative roles of organic anion transporting polypeptides (OATPs) in cell survival and progression of human cancers

    Article • Biopharmaceutics & Drug Disposition, October 2014, Wiley

    Takeo Nakanishi

  37. SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria

    Article • Biopharmaceutics & Drug Disposition, August 2014, Wiley

    Takeo Nakanishi

  38. Accumulation of Trans-1-Amino-3-[18F]Fluorocyclobutanecarboxylic Acid in Prostate Cancer due to Androgen-Induced Expression of Amino Acid Transporters

    Article • Molecular Imaging and Biology, June 2014, Springer Science + Business Media

    Takeo Nakanishi

  39. Transport mechanisms of hepatic uptake and bile excretion in clinical hepatobiliary scintigraphy with 99mTc-N-pyridoxyl-5-methyltryptophan

    Article • Nuclear Medicine and Biology, April 2014, Elsevier

    Takeo Nakanishi

  40. Substrate- and Dose-Dependent Drug Interactions with Grapefruit Juice Caused by Multiple Binding Sites on OATP2B1

    Article • Pharmaceutical Research, February 2014, Springer Science + Business Media

    Takeo Nakanishi

  41. More Relevant Prediction for In Vivo Drug Interaction of Candesartan Cilexetil on Hepatic Bile Acid Transporter BSEP Using Sandwich-cultured Hepatocytes

    Article • Drug Metabolism and Pharmacokinetics, January 2014, Japanese Society for the Study of Xenobiotics

    Takeo Nakanishi

  42. Mathematical Modeling of the in Vitro Hepatic Disposition of Mycophenolic Acid and Its Glucuronide in Sandwich-Cultured Human Hepatocytes

    Article • Molecular Pharmaceutics, December 2013, American Chemical Society (ACS)

    Takeo Nakanishi

  43. Bcrp1 transcription in mouse testis is controlled by a promoter upstream of a novel first exon (E1U) regulated by steroidogenic factor-1

    Article • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, December 2013, Elsevier

    Takeo Nakanishi

  44. OATP transporter-mediated drug absorption and interaction

    Article • Current Opinion in Pharmacology, December 2013, Elsevier

    Takeo Nakanishi

  45. How Does Whisky Lower Serum Urate Level?

    Article • Phytotherapy Research, September 2013, Wiley

    Takeo Nakanishi

  46. In Vivo Evidence of Organic Cation Transporter-Mediated Tracheal Accumulation of the Anticholinergic Agent Ipratropium in Mice

    Article • Journal of Pharmaceutical Sciences, September 2013, Elsevier

    Takeo Nakanishi

  47. Major Active Components in Grapefruit, Orange, and Apple Juices Responsible for OATP2B1-Mediated Drug Interactions

    Article • Journal of Pharmaceutical Sciences, September 2013, Elsevier

    Takeo Nakanishi

  48. Kinetic analyses of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2

    Article • Nuclear Medicine and Biology, July 2013, Elsevier

    Takeo Nakanishi

  49. A role of prostaglandin transporter in regulating PGE2 release from human bronchial epithelial BEAS-2B cells in response to LPS

    Article • March 2013, Bioscientifica

    Takeo Nakanishi

  50. Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate

    Article • Nephrology Dialysis Transplantation, January 2013, Oxford University Press (OUP)

    Takeo Nakanishi

  51. Cancer cells uptake porphyrinsviaheme carrier protein 1

    Article • Journal of Porphyrins and Phthalocyanines, January 2013, World Scientific Pub Co Pte Lt

    Takeo Nakanishi

  52. Functional Cooperation of SMCTs and URAT1 for Renal Reabsorption Transport of Urate

    Article • Drug Metabolism and Pharmacokinetics, January 2013, Japanese Society for the Study of Xenobiotics

    Takeo Nakanishi

  53. Major Active Components in Grapefruit, Orange, and Apple Juices Responsible for OATP2B1-Mediated Drug Interactions

    Article • Journal of Pharmaceutical Sciences, January 2013, Elsevier

    Takeo Nakanishi

  54. Long-Lasting Inhibitory Effect of Apple and Orange Juices, but Not Grapefruit Juice, on OATP2B1-Mediated Drug Absorption

    Article • Drug Metabolism and Disposition, December 2012, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  55. Enhanced expression of organic anion transporting polypeptides (OATPs) in androgen receptor-positive prostate cancer cells: Possible role of OATP1A2 in adaptive cell growth under androgen-depleted conditions

    Article • Biochemical Pharmacology, October 2012, Elsevier

    Takeo Nakanishi

  56. Application of quantitative time-lapse imaging (QTLI) for evaluation of Mrp2-based drug–drug interaction induced by liver metabolites

    Article • Toxicology and Applied Pharmacology, September 2012, Elsevier

    Takeo Nakanishi

  57. Active intestinal absorption of fluoroquinolone antibacterial agent ciprofloxacin by organic anion transporting polypeptide, Oatp1a5

    Article • Biopharmaceutics & Drug Disposition, August 2012, Wiley

    Takeo Nakanishi

  58. Novel LC-MS/MS Method for Simultaneous Quantification of KW-7158, a New Drug Candidate for Urinary Incontinence and Bladder Hyperactivity, and its Metabolites in Rat Plasma: A Pharmacokinetic Study in Male and Female Rats

    Article • Arzneimittelforschung, February 2012, Thieme Publishing Group

    Takeo Nakanishi

  59. Extra-Renal Elimination of Uric Acid via Intestinal Efflux Transporter BCRP/ABCG2

    Article • PLoS ONE, February 2012, PLOS

    Takeo Nakanishi

  60. Species differences in the pharmacokinetics of KW-7158 [(2S)-(+)-3,3,3-Trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide]: formation of hydrolyzed metabolite in human and animals

    Article • Xenobiotica, February 2012, Taylor & Francis

    Takeo Nakanishi

  61. Breast cancer resistance protein (BCRP/ABCG2): its role in multidrug resistance and regulation of its gene expression

    Article • Chinese Journal of Cancer, February 2012, Editorial Office of Chinese Journal of Cancer

    Takeo Nakanishi

  62. Effect of back pressure on emulsification of lipid nanodispersions in a high-pressure homogenizer

    Article • International Journal of Pharmaceutics, January 2012, Elsevier

    Takeo Nakanishi

  63. Functional Pleiotropy of Organic Anion Transporting Polypeptide OATP2B1 Due to Multiple Binding Sites

    Article • Drug Metabolism and Pharmacokinetics, January 2012, Japanese Society for the Study of Xenobiotics

    Takeo Nakanishi

  64. Genetic Polymorphisms of OATP Transporters and Their Impact on Intestinal Absorption and Hepatic Disposition of Drugs

    Article • Drug Metabolism and Pharmacokinetics, January 2012, Japanese Society for the Study of Xenobiotics

    Takeo Nakanishi

  65. Functional Characterization of Apical Transporters Expressed in Rat Proximal Tubular Cells (PTCs) in Primary Culture

    Article • Molecular Pharmaceutics, October 2011, American Chemical Society (ACS)

    Takeo Nakanishi

  66. Differential Effect of Grapefruit Juice on Intestinal Absorption of Statins Due to Inhibition of Organic Anion Transporting Polypeptide and/or P-glycoprotein

    Article • Journal of Pharmaceutical Sciences, September 2011, Elsevier

    Takeo Nakanishi

  67. Solute Carrier Transporters as Targets for Drug Delivery and Pharmacological Intervention for Chemotherapy

    Article • Journal of Pharmaceutical Sciences, September 2011, Elsevier

    Takeo Nakanishi

  68. Identification and characterization of the major alternative promoter regulating Bcrp1/Abcg2 expression in the mouse intestine

    Article • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, July 2011, Elsevier

    Takeo Nakanishi

  69. Identification and functional characterization of uric acid transporter Urat1 (Slc22a12) in rats

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, June 2011, Elsevier

    Takeo Nakanishi

  70. Oxaliplatin Transport Mediated by Organic Cation/Carnitine Transporters OCTN1 and OCTN2 in Overexpressing Human Embryonic Kidney 293 Cells and Rat Dorsal Root Ganglion Neurons

    Article • Journal of Pharmacology and Experimental Therapeutics, May 2011, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  71. Putative Transport Mechanism and Intracellular Fate of Trans-1-Amino-3-18F-Fluorocyclobutanecarboxylic Acid in Human Prostate Cancer

    Article • Journal of Nuclear Medicine, May 2011, Society of Nuclear Medicine

    Takeo Nakanishi

  72. Total Syntheses of (−)- and (+)-Goniomitine

    Article • Organic Letters, April 2011, American Chemical Society (ACS)

    Takeo Nakanishi

  73. Quantitative Time-Lapse Imaging-Based Analysis of Drug-Drug Interaction Mediated by Hepatobiliary Transporter, Multidrug Resistance-Associated Protein 2, in Sandwich-Cultured Rat Hepatocytes

    Article • Drug Metabolism and Disposition, March 2011, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  74. Carnitine Precursor γ-Butyrobetaine is a Novel Substrate of the Na+- and Cl−-dependent GABA Transporter Gat2

    Article • Drug Metabolism and Pharmacokinetics, January 2011, Japanese Society for the Study of Xenobiotics

    Takeo Nakanishi

  75. Drug Efflux by Breast Cancer Resistance Protein Is a Mechanism of Resistance to the Benzimidazole Insulin-Like Growth Factor Receptor/Insulin Receptor Inhibitor, BMS-536924

    Article • Molecular Cancer Therapeutics, January 2011, American Association for Cancer Research (AACR)

    Takeo Nakanishi

  76. Intestinal Absorption of HMG-CoA Reductase Inhibitor Pitavastatin Mediated by Organic Anion Transporting Polypeptide and P-Glycoprotein/Multidrug Resistance 1

    Article • Drug Metabolism and Pharmacokinetics, January 2011, Japanese Society for the Study of Xenobiotics

    Takeo Nakanishi

  77. A novel xenobiotic responsive element regulated by aryl hydrocarbon receptor is involved in the induction of BCRP/ABCG2 in LS174T cells

    Article • Biochemical Pharmacology, December 2010, Elsevier

    Takeo Nakanishi

  78. Organic Cation Transporter-Mediated Renal Secretion of Ipratropium and Tiotropium in Rats and Humans

    Article • Drug Metabolism and Disposition, October 2010, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  79. Uptake transporter organic anion transporting polypeptide 1B3 contributes to the growth of estrogen-dependent breast cancer

    Article • The Journal of Steroid Biochemistry and Molecular Biology, October 2010, Elsevier

    Takeo Nakanishi

  80. Impact of system L amino acid transporter 1 (LAT1) on proliferation of human ovarian cancer cells: A possible target for combination therapy with anti-proliferative aminopeptidase inhibitors

    Article • Biochemical Pharmacology, September 2010, Elsevier

    Takeo Nakanishi

  81. Intestinal Absorption of HMG-CoA Reductase Inhibitor Pravastatin Mediated by Organic Anion Transporting Polypeptide

    Article • Pharmaceutical Research, August 2010, Springer Science + Business Media

    Takeo Nakanishi

  82. Side-population cells in luminal-type breast cancer have tumour-initiating cell properties and are regulated by HER2 expression and signalling

    Article • British Journal of Cancer, February 2010, Springer Science + Business Media

    Takeo Nakanishi

  83. Transport of Ipratropium, an Anti-Chronic Obstructive Pulmonary Disease Drug, Is Mediated by Organic Cation/Carnitine Transporters in Human Bronchial Epithelial Cells: Implications for Carrier-Mediated Pulmonary Absorption

    Article • Molecular Pharmaceutics, January 2010, American Chemical Society (ACS)

    Takeo Nakanishi

  84. Involvement of Choline Transporter-Like Proteins, CTL1 and CTL2, in Glucocorticoid-Induced Acceleration of Phosphatidylcholine Synthesis via Increased Choline Uptake

    Article • Biological and Pharmaceutical Bulletin, January 2010, Pharmaceutical Society of Japan

    Takeo Nakanishi

  85. Methods to Evaluate Transporter Activity in Cancer

    Article • January 2010, Springer Science + Business Media

    Takeo Nakanishi

  86. Renal Secretion of Uric Acid by Organic Anion Transporter 2 (OAT2/SLC22A7) in Human

    Article • Biological and Pharmaceutical Bulletin, January 2010, Pharmaceutical Society of Japan

    Takeo Nakanishi

  87. Hepatic uptake of γ-butyrobetaine, a precursor of carnitine biosynthesis, in rats

    Article • AJP Gastrointestinal and Liver Physiology, October 2009, American Physiological Society

    Takeo Nakanishi

  88. Species Difference in the Effect of Grapefruit Juice on Intestinal Absorption of Talinolol between Human and Rat

    Article • Journal of Pharmacology and Experimental Therapeutics, September 2009, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  89. Organic anion transporter OAT1 is involved in renal handling of citrulline

    Article • AJP Renal Physiology, July 2009, American Physiological Society

    Takeo Nakanishi

  90. Transport characteristics of L-citrulline in renal apical membrane of proximal tubular cells

    Article • Biopharmaceutics & Drug Disposition, April 2009, Wiley

    Takeo Nakanishi

  91. Preclinical Studies of Vorinostat (Suberoylanilide Hydroxamic Acid) Combined with Cytosine Arabinoside and Etoposide for Treatment of Acute Leukemias

    Article • Clinical Cancer Research, February 2009, American Association for Cancer Research (AACR)

    Takeo Nakanishi

  92. The 44-kDa Pim-1 Kinase Phosphorylates BCRP/ABCG2 and Thereby Promotes Its Multimerization and Drug-resistant Activity in Human Prostate Cancer Cells

    Article • Journal of Biological Chemistry, December 2007, American Society for Biochemistry & Molecular Biology (ASBMB)

    Takeo Nakanishi

  93. Alterations in the Mitochondrial Proteome of Adriamycin Resistant MCF-7 Breast Cancer Cells

    Article • Journal of Proteome Research, September 2006, American Chemical Society (ACS)

    Takeo Nakanishi

  94. Characteristics of Transcription-regulatory Elements for Gene Expression from Plasmid Vectors in Human Trophoblast Cell Lines

    Article • Placenta, September 2006, Elsevier

    Takeo Nakanishi

  95. Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRP-mediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression

    Article • Blood, July 2006, American Society of Hematology

    Takeo Nakanishi

  96. Novel 5′ Untranslated Region Variants of BCRP mRNA Are Differentially Expressed in Drug-Selected Cancer Cells and in Normal Human Tissues: Implications for Drug Resistance, Tissue-Specific Expression, and Alternative Promoter Usage

    Article • Cancer Research, May 2006, American Association for Cancer Research (AACR)

    Takeo Nakanishi

  97. Thapsigargin resistance in human prostate cancer cells

    Article • Cancer, January 2006, Wiley

    Takeo Nakanishi

  98. Comparison of transgene expression mediated by several Fiber-modified adenovirus vectors in trophoblast cells

    Article • Placenta, November 2005, Elsevier

    Takeo Nakanishi

  99. The ErbB3-binding protein Ebp1 suppresses androgen receptor-mediated gene transcription and tumorigenesis of prostate cancer cells

    Article • Proceedings of the National Academy of Sciences, June 2005, Proceedings of the National Academy of Sciences

    Takeo Nakanishi

  100. Breast cancer resistance protein (BCRP/MXR/ABCG2) in adult acute lymphoblastic leukaemia: frequent expression and possible correlation with shorter disease-free survival

    Article • British Journal of Haematology, November 2004, Wiley

    Takeo Nakanishi

  101. Plasma pharmacokinetics and tissue distribution of the breast cancer resistance protein (BCRP/ABCG2) inhibitor fumitremorgin C in SCID mice bearing T8 tumors

    Article • Cancer Chemotherapy and Pharmacology, October 2004, Springer Science + Business Media

    Takeo Nakanishi

  102. Breast cancer resistance protein (BCRP/MXR/ABCG2) in acute myeloid leukemia: discordance between expression and function

    Article • Leukemia, June 2004, Springer Science + Business Media

    Takeo Nakanishi

  103. The Stem Cell Marker Bcrp/ABCG2 Enhances Hypoxic Cell Survival through Interactions with Heme

    Article • Journal of Biological Chemistry, March 2004, American Society for Biochemistry & Molecular Biology (ASBMB)

    Takeo Nakanishi

  104. Functional Characterization of Human Breast Cancer Resistance Protein (BCRP, ABCG2) Expressed in the Oocytes of Xenopus laevis

    Article • Molecular Pharmacology, November 2003, American Society for Pharmacology & Experimental Therapeutics (ASPET)

    Takeo Nakanishi

  105. Involvement of OCTN1 (SLC22A4) in pH-Dependent Transport of Organic Cations

    Article • Molecular Pharmaceutics, October 2003, American Chemical Society (ACS)

    Takeo Nakanishi

  106. Transport of d-Serine via the Amino Acid Transporter ATB0,+ Expressed in the Colon

    Article • Biochemical and Biophysical Research Communications, February 2002, Elsevier

    Takeo Nakanishi

  107. Na+- and Cl–-coupled active transport of nitric oxide synthase inhibitors via amino acid transport system B0,+

    Article • Journal of Clinical Investigation, April 2001, American Society for Clinical Investigation

    Takeo Nakanishi

  108. Rapid Report

    Article • The Journal of Physiology, April 2001, Wiley

    Takeo Nakanishi

  109. Structure, Function, and Tissue Expression Pattern of Human SN2, a Subtype of the Amino Acid Transport System N

    Article • Biochemical and Biophysical Research Communications, March 2001, Elsevier

    Takeo Nakanishi

  110. Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal muscle

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, December 2000, Elsevier

    Takeo Nakanishi

  111. Primary Structure, Genomic Organization, and Functional and Electrogenic Characteristics of Human System N 1, a Na+- and H+-coupled Glutamine Transporter

    Article • Journal of Biological Chemistry, May 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Takeo Nakanishi

  112. Cloning of an Amino Acid Transporter with Functional Characteristics and Tissue Expression Pattern Identical to That of System A

    Article • Journal of Biological Chemistry, March 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Takeo Nakanishi

  113. Cancer cell-targeted drug delivery utilizing oligopeptide transport activity

    Article • International Journal of Cancer, January 2000, Wiley

    Takeo Nakanishi

  114. A new orally active antitumor 1 R ,2 R -cyclohexanediamine-platinum(IV) complex: trans -( n -valerato)chloro(1 R ,2 R -cyclohexanediamine) (oxalato)platinum(IV)

    Article • Cancer Chemotherapy and Pharmacology, February 1999, Springer Science + Business Media

    Takeo Nakanishi

  115. Improvement of L-dopa absorption by dipeptidyl derivation, utilizing peptide transporter PepT1

    Article • Journal of Pharmaceutical Sciences, December 1998, Elsevier

    Takeo Nakanishi

  116. Direct Evidence for Peptide Transporter (PepT1)-Mediated Uptake of a Nonpeptide Prodrug, Valacyclovir

    Article • Biochemical and Biophysical Research Communications, September 1998, Elsevier

    Takeo Nakanishi

  117. Significance of water solubility in the gastrointestinal absorption of trans-bis(n-valerato)(1 R,2R-cyclohexanediamine)(oxalato)platinum(IV), an orally active antitumor platinum complex, and its analogs

    Article • Anti-Cancer Drugs, February 1998, Wolters Kluwer Health

    Takeo Nakanishi

  118. Immunolocalization and pharmacological relevance of oligopeptide transporter PepT1 in intestinal absorption of β-lactam antibiotics

    Article • FEBS Letters, August 1996, Wiley

    Takeo Nakanishi

  119. An orally active antitumor cyclohexanediamine-Pt(IV) complex

    Article • Anti-Cancer Drugs, May 1996, Wolters Kluwer Health

    Takeo Nakanishi