All Stories

  1. Physicochemical stability and toxicity assessment of cimitrypazepine, an azepino[5,4,3- cd ]indole alkaloid
  2. The importance of blood trace elements in the biomonitoring of agrochemicals exposure and effects on DNA and epigenetic alterations
  3. In vitro immunotoxic evaluation of herbicides in RAW 264.7 cells
  4. The Influence of Blood Titanium Levels on DNA Damage in Brazilian Workers Occupationally Exposed to Different Chemical Agents
  5. Specific Antidermatophytic Activity of Trifluoromethylthiolated Cinnamate Derivatives: A New Approach to the Therapy of Superficial Fungal Infections of the Skin
  6. Cytotoxicity induced by three commercial neonicotinoid insecticide formulations in differentiated human neuroblastoma SH-SY5Y cells
  7. Mitochondrial impairment related to the immunotoxicity of the herbicides clomazone, glyphosate and sulfentrazone in THP-1 cells
  8. Physico-chemical Characterization and Biosafety Evaluation of Atorvastatin Nanocapsules Co-encapsulated with Ginger Oil or Grape Seed Oil
  9. Immunomodulatory effect of imidacloprid on macrophage RAW 264.7 cells
  10. LaSOM335, active against bladder cancer cells, interferes withLet‐60(hRas) and reducesCD73 expression/activity
  11. Editorial: Genetic toxicology in Brazil
  12. DoE development of ionic gradient liposomes: A successful approach to improve encapsulation, prolong anesthesia and decrease the toxicity of etidocaine
  13. Acute Toxicity Evaluation of Phosphatidylcholine Nanoliposomes Containing Nisin in Caenorhabditis elegans
  14. Antiproliferative activity and toxicity evaluation of 1,2,3-triazole and 4-methyl coumarin hybrids in the MCF7 breast cancer cell line
  15. Characterization and in vivo toxicological evaluation of multi-walled carbon nanotubes: a low-dose repeated intratracheal administration study
  16. The Role of Alternative Toxicological Trials in Drug Discovery Programs. The Case of Caenorhabditis elegans and Other Methods
  17. Toxicity of pesticides widely applied on soybean cultivation: Synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells
  18. Imidacloprid-based commercial pesticide causes behavioral, biochemical, and hematological impairments in Wistar rats
  19. Toxic effects of pesticides on cellular and humoral immunity: an overview
  20. Brazilian workers occupationally exposed to different toxic agents: A systematic review on DNA damage
  21. Chemobrain in Breast Cancer: Mechanisms, Clinical Manifestations, and Potential Interventions
  22. Vitamin A deficiency and associated risk factors in children aged 12–59 months living in poorest municipalities in the South Region of Brazil
  23. Children Environmentally Exposed to Agrochemicals in Rural Areas Present Changes in Oxidative Status and DNA Damage
  24. Levamisole, a cocaine cutting agent, induces acute and subchronic systemic alterations in Wistar rats
  25. Bioassays to screen the toxicity in drinking water samples collected in Brazilian rural area
  26. Occupational exposure to crystalline silica and peripheral biomarkers: An update
  27. Occupational exposure assessment in professionals who manipulate and administer antineoplastic drugs in a university hospital in Southern Brazil
  28. Sintocalmy, a Passiflora incarnata Based Herbal, Attenuates Morphine Withdrawal in Mice
  29. Dietary exposure to mercury and its relation to cytogenetic instability in populations from “La Mojana” region, northern Colombia
  30. Cellular response to chemicals present in air pollution in occupationally exposed workers and its potential cancer susceptibility
  31. Atropisomerism in N 1‐aryl Substituted 3,4‐dihydropyrimidin‐2(1H)‐thiones
  32. Corrigendum
  33. Ochratoxin A presence in Cabernet Sauvignon wine changes antioxidant activityin vitroand oxidative stress markersin vivo
  34. Trichomonas vaginalis NTPDase inhibited by lycorine modulates the parasite-neutrophil interaction
  35. New pharmacological findings linked to biphenyl DHPMs, kinesin Eg5 ligands: anticancer and antioxidant effects
  36. Biochemical, hematological and immunological parameters and relationship with occupational exposure to pesticides and metals
  37. Toxicology study of nanoclays adsorbed with the antimicrobial peptide nisin on Caenorhabditis elegans
  38. Occupational risk assessment of exposure to metals in chrome plating workers
  39. Biomarkers of exposure, effect, and susceptibility in occupational exposure to traffic‐related air pollution: A review
  40. Oral Treatment of Spontaneously Hypertensive Rats with Captopril-Surface Functionalized Furosemide-Loaded Multi-Wall Lipid-Core Nanocapsules
  41. A SIMPLE AND SENSITIVE LC-MS/MS METHOD FOR THE DETERMINATION OF S-PHENYLMERCAPTURIC ACID IN HUMAN URINE
  42. In vitro toxic evaluation of two gliptins and their main impurities of synthesis
  43. Evaluation of immunological, inflammatory, and oxidative stress biomarkers in gasoline station attendants
  44. Melatonin-loaded lipid-core nanocapsules protect against lipid peroxidation caused by paraquat through increased SOD expression in Caenorhabditis elegans
  45. Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans
  46. Piperazine designer drugs elicit toxicity in the alternative in vivo model Caenorhabditis elegans
  47. Toxic elements in packed red blood cells from smoker donors: a risk for paediatric transfusion?
  48. Reprotoxicity of glyphosate-based formulation in Caenorhabditis elegans is not due to the active ingredient only
  49. Hepatoprotective activity of Verbena litoralis, Verbena montevidensis and their main iridoid, brasoside
  50. In vitro cardiotoxicity evaluation of graphene oxide
  51. Estimation of total arsenic contamination and exposure in Brazilian rice and infant cereals
  52. Evaluation of hematological, biochemical parameters and thiol enzyme activity in chrome plating workers
  53. Inflammatory and oxidative stress biomarkers at protein and molecular levels in workers occupationally exposed to crystalline silica
  54. Ethyl 4-(2-fluorophenyl)-6-methyl-2-thioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
  55. Exposure to environment chemicals and its possible role in endocrine disruption of children from a rural area
  56. Combination of energy drink and alcohol and its associated toxicity
  57. The role of B7 costimulation in benzene immunotoxicity and its potential association with cancer risk
  58. Inflammatory and oxidative stress parameters as potential early biomarkers for silicosis
  59. Energy drink and alcohol combination leads to kidney and liver alterations in rats
  60. Synthesis and in vitro Evaluation of 1,2,3-triazole-4-chloromethylcoumarins with Antioxidant Activity
  61. In vitro toxicity assessment of rivaroxaban degradation products and kinetic evaluation to decay process
  62. Protective effect of Uncaria tomentosa extract against oxidative stress and genotoxicity induced by glyphosate-Roundup® using zebrafish (Danio rerio) as a model
  63. Are metals and pyrene levels additional factors playing a pivotal role in air pollution-induced inflammation in taxi drivers?
  64. Effect of N-1 arylation of monastrol on kinesin Eg5 inhibition in glioma cell lines
  65. Microcystin-LR exposure induces oxidative damage in Caenorhabditis elegans: Protective effect of lutein extracted from marigold flowers
  66. Adenosine reduces reactive oxygen species and interleukin-8 production by Trichomonas vaginalis-stimulated neutrophils
  67. Ozone generated by air purifier in low concentrations: friend or foe?
  68. Long-Term Excessive Selenium Supplementation Induces Hypertension in Rats
  69. Interference of single walled carbon nanotubes (SWCNT) in the measurement of lipid peroxidation in aquatic organisms through TBARS assay
  70. Biomonitoring of gasoline station attendants exposed to benzene: Effect of gender
  71. DNA damage in the elderly is associated with 5-MTHF levels: a pro-oxidant activity
  72. Environmental exposure and effects on health of children from a tobacco-producing region
  73. Association between inflammation processes, DNA damage, and exposure to environmental pollutants
  74. Acute toxicity evaluation of polycyclic aromatic hydrocarbons (PAHs) present in asphalt fumes in the alternative model Caenorhabditis elegans
  75. Protective effects of melatonin-loaded lipid-core nanocapsules against paraquat damage in the alternative in vivo model Caenorhabditis elegans
  76. Polyphenol-rich food general and on pregnancy effects: a review
  77. Associations among environmental exposure to manganese, neuropsychological performance, oxidative damage and kidney biomarkers in children
  78. Trichomonas vaginalis NTPDase and ecto-5′-nucleotidase hydrolyze guanine nucleotides and increase extracellular guanosine levels under serum restriction
  79. Gender differences in biochemical markers and oxidative stress of rats after 28 days oral exposure to a mixture used for weight loss containing p-synephrine, ephedrine, salicin, and caffeine
  80. Evaluation of potential acute cardiotoxicity of biodegradable nanocapsules in rats by intravenous administration
  81. Combining the Pharmacophore Features of Coumarins and 1,4-Substituted 1,2,3-Triazoles to Design New Acetylcholinesterase Inhibitors: Fast and Easy Generation of 4-Methylcoumarins/1,2,3-triazoles Conjugates via Click Chemistry
  82. Polarimetry as an Analytical Method to Quantify Limonene-Loaded Nanoemulsions.
  83. Protective effects of melatonin-loaded lipid-core nanocapsules on paraquat-induced cytotoxicity and genotoxicity in a pulmonary cell line
  84. Effects of genetic polymorphisms on antioxidant status and concentrations of the metals in the blood of riverside Amazonian communities co-exposed to Hg and Pb
  85. Relationship between blood metals and inflammation in taxi drivers
  86. Haloperidol-loaded lipid-core polymeric nanocapsules reduce DNA damage in blood and oxidative stress in liver and kidneys of rats
  87. Early hematological and immunological alterations in gasoline station attendants exposed to benzene
  88. Behavioral and dopaminergic damage induced by acute iron toxicity in Caenorhabditis elegans
  89. Do poly(epsilon-caprolactone) lipid-core nanocapsules induce oxidative or inflammatory damage after in vivo subchronic treatment?
  90. Cognitive deficits and ALA-D-inhibition in children exposed to multiple metals
  91. New Insights into the Chemistry and Antioxidant Activity of Coumarins
  92. Liver δ-Aminolevulinate Dehydratase Activity is Inhibited by Neonicotinoids and Restored by Antioxidant Agents
  93. Are Delta-Aminolevulinate Dehydratase Inhibition and Metal Concentrations Additional Factors for the Age-Related Cognitive Decline?
  94. Evaluation of Toxic Metals and Essential Elements in Children with Learning Disabilities from a Rural Area of Southern Brazil
  95. Fatty Acid Status and Its Relationship to Cognitive Decline and Homocysteine Levels in the Elderly
  96. Urinary 1-Hydroxypyrene is Associated with Oxidative Stress and Inflammatory Biomarkers in Acute Myocardial Infarction
  97. Nitric oxide and reactive species are modulated in the polyphenol-induced ductus arteriosus constriction in pregnant sheep
  98. Evaluation of genotoxicity in workers exposed to benzene and atmospheric pollutants
  99. Atherosclerotic process in taxi drivers occupationally exposed to air pollution and co-morbidities
  100. EXPERIMENTAL CONSTRICTION OF FETAL DUCTUS ARTERIOSUS, OXIDATIVE STRESS, AND POLYPHENOL EXCRETION AFTER MATERNAL POLYPHENOL-RICH DIET IN LATE PREGNANCY
  101. Subchronic Oral Administration of Benzo[a]pyrene Impairs Motor and Cognitive Behavior and Modulates S100B Levels and MAPKs in Rats
  102. In vitro effect of genistein on DNA damage in leukocytes from mucopolysaccharidosis IVA patients
  103. In vivo toxicological evaluation of polymeric nanocapsules after intradermal administration
  104. Methionine Stimulates Motor Impairment And Cerebellar Mercury Deposition in Methylmercury-Exposed Mice
  105. Polymorphisms in glutathione-related genes modify mercury concentrations and antioxidant status in subjects environmentally exposed to methylmercury
  106. Biomarkers of occupational exposure to air pollution, inflammation and oxidative damage in taxi drivers
  107. Polymeric Nanoparticles: In Vivo Toxicological Evaluation, Cardiotoxicity, and Hepatotoxicity
  108. Evaluation of biochemical and redox parameters in rats fed with corn grown in soil amended with urban sewage sludge
  109. Genotoxicity and oxidative stress in gasoline station attendants
  110. The Antioxidant Activity of Coumarins and Flavonoids
  111. The Antioxidant Activity of Coumarins and Flavonoids
  112. Development and validation of a food frequency questionnaire for consumption of polyphenol-rich foods in pregnant women
  113. A LC-UV method to assay N-acetylcysteine without derivatization: analyses of pharmaceutical products
  114. Plasma Malondialdehyde Levels and Risk Factors for the Development of Chronic Complications in Type 2 Diabetic Patients on Insulin Therapy
  115. Acute and Subchronic Toxicity Evaluation of Poly(ɛ-Caprolactone) Lipid-Core Nanocapsules in Rats
  116. Evaluation of lipid damage related to pathological and physiological conditions
  117. Evaluation of oxidative biomarkers in rats fed with corn cropped in different concentrations of urban sludge
  118. Evaluation of GlutathioneS-transferaseGSTM1andGSTT1Polymorphisms and Methylmercury Metabolism in an Exposed Amazon Population
  119. Simultaneous quantification of lycopene, β-carotene, retinol and α -tocopherol in plasma after a simple extraction procedure: stability study and application to human volunteers
  120. Fetal ductal constriction caused by maternal ingestion of green tea in late pregnancy: an experimental study
  121. Evaluation of genotoxicity and oxidative damage in painters exposed to low levels of toluene
  122. Evaluation of the Antioxidant Capacity of Synthesized Coumarins
  123. Ischemia modified albumin and carbonyl protein as potential biomarkers of protein oxidation in hemodialysis
  124. Analysis of the NTPDase and ecto-5'-nucleotidase profiles in serum-limited Trichomonas vaginalis
  125. Aminolevulinate dehydratase (δ-ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations
  126. Response to the letter of Dr. A. Nersesyan
  127. Designer drugs: aspectos analíticos e biológicos
  128. Letter to editor
  129. Reduction of butyrylcholinesterase activity in plasma from patients with disorders of propionate metabolism is prevented by treatment with L-carnitine and protein restriction
  130. Quantificação sérica de vitamina C por CLAE-UV e estudo de estabilidade
  131. Reversal of fetal ductal constriction after maternal restriction of polyphenol-rich foods: an open clinical trial
  132. Evaluation of toxic effects of a diet containing fish contaminated with methylmercury in rats mimicking the exposure in the Amazon riverside population
  133. The relationships between exogenous and endogenous antioxidants with the lipid profile and oxidative damage in hemodialysis patients
  134. Blood thioredoxin reductase activity, oxidative stress and hematological parameters in painters and battery workers: relationship with lead and cadmium levels in blood
  135. Experimental evidence of oxidative stress in plasma of homocystinuric patients: A possible role for homocysteine
  136. N-acetylcysteine on oxidative damage in diabetic rats
  137. Acute toxicological evaluation of lipid-core nanocapsules
  138. Subchronic toxicological evaluation of lipid-core nanocapsules
  139. Association among Microalbuminuria and Oxidative Stress Biomarkers in Patients with Type 2 Diabetes
  140. Ischemia-modified albumin as an oxidative stress biomarker in obesity
  141. Occupational risk assessment of oxidative stress and genotoxicity in workers exposed to paints during a working week
  142. Presence of synthetic pharmaceuticals as adulterants in slimming phytotherapeutic formulations and their analytical determination
  143. Evidence that l-Carnitine and Selenium Supplementation Reduces Oxidative Stress in Phenylketonuric Patients
  144. Possíveis efeitos do cobre sanguíneo sobre parâmetros hematológicos em idosas
  145. A new method for the simultaneous determination of 1,4-benzodiazepines and amfepramone as adulterants in phytotherapeutic formulations by voltammetry
  146. Effects of low-level exposure to xenobiotics present in paints on oxidative stress in workers
  147. Determination of synthetic pharmaceuticals in phytotherapeutics by capillary zone electrophoresis with contactless conductivity detection (CZE-C4D)
  148. Aluminum Loading in Preterm Neonates Revisited
  149. Could selenium and omega-3 modify the oxidative damage promoted by methylmercury at low doses in rats?
  150. Intoxicação em cães e gatos: diagnóstico toxicológico empregando cromatografia em camada delgada e cromatografia líquida de alta pressão com detecção ultravioleta em amostras estomacais
  151. Aluminum Content in Intravenous Solutions for Administration to Neonates
  152. Sub-Chronic Exposure to Methylmercury at Low Levels Decreases Butyrylcholinesterase Activity in Rats
  153. Mercury exposure and oxidative stress in communities of the Brazilian Amazon
  154. Determination of sodium, potassium, calcium, magnesium, zinc, and iron in emulsified egg samples by flame atomic absorption spectrometry
  155. Determination of metallic contaminants in human recombinant erythropoietin (EPO) formulations by adsorptive cathodic stripping voltammetry and UV photo-decomposition of samples
  156. Subchronic toxicity of Citrus aurantium L. (Rutaceae) extract and p-synephrine in mice
  157. Presence of p-synephrine in teas commercialized in Porto Alegre (RS/Brazil)
  158. Low level and sub-chronic exposure to methylmercury induces hypertension in rats: nitric oxide depletion and oxidative damage as possible mechanisms
  159. The plasma retinol levels as pro-oxidant/oxidant agents in haemodialysis patients
  160. Importance of the lipid peroxidation biomarkers and methodological aspects FOR malondialdehyde quantification
  161. Sensitivity of young rats to nicotine exposure: Physiological and biochemical parameters
  162. Chronic hyperhomocysteinemia alters antioxidant defenses and increases DNA damage in brain and blood of rats: Protective effect of folic acid
  163. Low levels of methylmercury induce DNA damage in rats: protective effects of selenium
  164. Role of medication in the level of aluminium in the blood of chronic haemodialysis patients
  165. Selenium minimize DNA damage in rats exposed to low dose of methylmercury
  166. Low levels of methylmercury induce DNA damage in rats: protective effects of selenium
  167. Concentrations of p-synephrine in fruits and leaves of Citrus species (Rutaceae) and the acute toxicity testing of Citrus aurantium extract and p-synephrine
  168. Screening for in vivo (anti)estrogenic activity of ephedrine and p-synephrine and their natural sources Ephedra sinica Stapf. (Ephedraceae) and Citrus aurantium L. (Rutaceae) in rats
  169. The influence of the hemodialysis treatment time under oxidative stress biomarkers in chronic renal failure patients
  170. Tissue digestion for aluminum determination in experimental animal studies
  171. Butyrylcholinesterase activity is reduced in haemodialysis patients: Is there association with hyperhomocysteinemia and/or oxidative stress?
  172. Influence of chronic exercise on reserpine-induced oxidative stress in rats: Behavioral and antioxidant evaluations
  173. Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain
  174. Quantification of reduced glutathione by HPLC-UV in erythrocytes of hemodialysis patients
  175. Effect of astaxanthin on kidney function impairment and oxidative stress induced by mercuric chloride in rats
  176. Avaliação da estabilidade do marcador plasmático do estresse oxidativo: malondialdeído
  177. Quantificação simultânea de indicadores biológicos de exposição a solventes orgânicos por cromatografia líquida de alta eficiência
  178. Determinação voltamétrica de metais em águas e fluidos biológicos empregando mineralização de amostras com radiação ultravioleta
  179. The influence of the serum vitamin C levels on oxidative stress biomarkers in elderly women
  180. Os riscos e danos nas intoxicações por paraquat em animais domésticos
  181. Quantificação laboratorial de cobre sérico por espectrofotometria Vis comparável à espectrometria de absorção atômica com chama
  182. Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: A comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates
  183. Human erythrocyte δ-aminolevulinate dehydratase activity and oxidative stress in hemodialysis patients
  184. Influência de desproteinizantes ácidos na quantificação da glutationa reduzida eritrocitária por CLAE-UV
  185. Independency of myocardial stunning of endothelial stunning?
  186. Reduction in β-myosin heavy chains in stunned myocardium as assessed by nondenaturing gel electrophoresis
  187. Lactational exposure to inorganic mercury: Evidence of neurotoxic effects
  188. Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography–visible detection
  189. Voltammetric behavior of amfepramone (diethylpropion) at the hanging mercury drop electrode and its analytical determination in pharmaceutical formulations
  190. Ion-exchange and potentiometric characterization of Al–cystine and Al–cysteine complexes
  191. Drugs as a hidden source of aluminium for chronic renal patients
  192. Cerebellar thiol status and motor deficit after lactational exposure to methylmercury
  193. Aspectos gerais e diagnóstico clinicolaboratorial da intoxicação por paraquat
  194. Fisiopatologia da deficiência de vitamina B12 e seu diagnóstico laboratorial
  195. Effect of Slaughter Method on Postmortem Changes of Grass Carp ( Ctenopharyngodon idella ) Stored in Icesti
  196. Determination of thiamine in blood serum and urine by high-performance liquid chromatography with direct injection and post-column derivatization
  197. Comparison of ultrafiltration and solid phase extraction for the separation of free and protein-bound serum copper for the Wilson's disease diagnosis
  198. 466 Hydroxyl peroxide and peroxynitrite contribute differently to the ischemia-reperfusion injury in the rabbit myocardium
  199. Electrophoretic Separation of Ventricular Myosin Isoenzymes Using a Native Polyacrylamide Minigel System
  200. Das isolierte Kaninchenherz: ein Vergleich zwischen fünf Varianten
  201. Contribution of the raw material to the aluminum contamination in parenterals
  202. Influence of the glass packing on the contamination of pharmaceutical products by aluminum. Part I: Salts, glucose, heparin and albumin
  203. Polarographic determination of cyanide as nickelcyano complex in blood plasma after selective extraction in a methylene blue impregnated polyethylene column
  204. Deproteinization of blood serum by acid treatment and microwave irradiation for the determinationof aluminium by electrothermal atomicabsorption spectrometry
  205. O problema da contaminação na determinação de traços de alumínio
  206. Liquid Chromatography With Ultraviolet Absorbance Detection of Ethylenethiourea in Blood Serum After Microwave Irradiation as an Auxiliary Cleanup Step