All Stories

  1. Synergic Effect of Fluconazole and Quinoline Derivatives Combination Against Cryptococcus spp., Mechanisms of Action and Toxicity
  2. Evaluation of Neurotoxicity of NBOH Derivatives
  3. Mineradores Gaúchos Expostos a Silício Urinário: um estudo da nefrotoxicidade
  4. Taurine reduces intracellular glucose accumulation in fructose-treated Caenorhabditis elegans
  5. Effects of repeated administration of oxandrolone in female wistar rats undergoing strength training
  6. Secnidazole and metronidazole in the treatment of Trichomoniasis: Comparative study of the mechanism of action and development of innovative 3D printed intrauterine devices
  7. In vitro and In silico Degradation Study Applied to the Carbapenems Meropenem and Imipenem
  8. Influence of the polymer on the physicochemical characterization and in vitro cutaneous performance of clobetasol gels
  9. Physicochemical stability and toxicity assessment of cimitrypazepine, an azepino[5,4,3- cd ]indole alkaloid
  10. Flumetralin based plant growth regulator used in tobacco cultivation induces immune and cytotoxicity in vitro
  11. The importance of blood trace elements in the biomonitoring of agrochemicals exposure and effects on DNA and epigenetic alterations
  12. Synergistic toxicity of glyphosate- and 2,4-Dichlorophenoxyacetic acid-based formulations on Caenorhabditis elegans
  13. In vitro immunotoxic evaluation of herbicides in RAW 264.7 cells
  14. The Influence of Blood Titanium Levels on DNA Damage in Brazilian Workers Occupationally Exposed to Different Chemical Agents
  15. Specific Antidermatophytic Activity of Trifluoromethylthiolated Cinnamate Derivatives: A New Approach to the Therapy of Superficial Fungal Infections of the Skin
  16. Cytotoxicity induced by three commercial neonicotinoid insecticide formulations in differentiated human neuroblastoma SH-SY5Y cells
  17. Mitochondrial impairment related to the immunotoxicity of the herbicides clomazone, glyphosate and sulfentrazone in THP-1 cells
  18. Physico-chemical Characterization and Biosafety Evaluation of Atorvastatin Nanocapsules Co-encapsulated with Ginger Oil or Grape Seed Oil
  19. Immunomodulatory effect of imidacloprid on macrophage RAW 264.7 cells
  20. LaSOM335, active against bladder cancer cells, interferes withLet‐60(hRas) and reducesCD73 expression/activity
  21. Editorial: Genetic toxicology in Brazil
  22. DoE development of ionic gradient liposomes: A successful approach to improve encapsulation, prolong anesthesia and decrease the toxicity of etidocaine
  23. Acute Toxicity Evaluation of Phosphatidylcholine Nanoliposomes Containing Nisin in Caenorhabditis elegans
  24. Antiproliferative activity and toxicity evaluation of 1,2,3-triazole and 4-methyl coumarin hybrids in the MCF7 breast cancer cell line
  25. Characterization and in vivo toxicological evaluation of multi-walled carbon nanotubes: a low-dose repeated intratracheal administration study
  26. The Role of Alternative Toxicological Trials in Drug Discovery Programs. The Case of Caenorhabditis elegans and Other Methods
  27. Toxicity of pesticides widely applied on soybean cultivation: Synergistic effects of fipronil, glyphosate and imidacloprid in HepG2 cells
  28. Imidacloprid-based commercial pesticide causes behavioral, biochemical, and hematological impairments in Wistar rats
  29. Toxic effects of pesticides on cellular and humoral immunity: an overview
  30. Brazilian workers occupationally exposed to different toxic agents: A systematic review on DNA damage
  31. Chemobrain in Breast Cancer: Mechanisms, Clinical Manifestations, and Potential Interventions
  32. Vitamin A deficiency and associated risk factors in children aged 12–59 months living in poorest municipalities in the South Region of Brazil
  33. Children Environmentally Exposed to Agrochemicals in Rural Areas Present Changes in Oxidative Status and DNA Damage
  34. Levamisole, a cocaine cutting agent, induces acute and subchronic systemic alterations in Wistar rats
  35. Bioassays to screen the toxicity in drinking water samples collected in Brazilian rural area
  36. Occupational exposure to crystalline silica and peripheral biomarkers: An update
  37. Occupational exposure assessment in professionals who manipulate and administer antineoplastic drugs in a university hospital in Southern Brazil
  38. Sintocalmy, a Passiflora incarnata Based Herbal, Attenuates Morphine Withdrawal in Mice
  39. Dietary exposure to mercury and its relation to cytogenetic instability in populations from “La Mojana” region, northern Colombia
  40. Cellular response to chemicals present in air pollution in occupationally exposed workers and its potential cancer susceptibility
  41. Oxidative damage, inflammation, genotoxic effect, and global DNA methylation caused by inhalation of formaldehyde and the purpose of melatonin
  42. Atropisomerism in N 1‐aryl Substituted 3,4‐dihydropyrimidin‐2(1H)‐thiones
  43. Corrigendum
  44. Ochratoxin A presence in Cabernet Sauvignon wine changes antioxidant activityin vitroand oxidative stress markersin vivo
  45. Trichomonas vaginalis NTPDase inhibited by lycorine modulates the parasite-neutrophil interaction
  46. New pharmacological findings linked to biphenyl DHPMs, kinesin Eg5 ligands: anticancer and antioxidant effects
  47. Biochemical, hematological and immunological parameters and relationship with occupational exposure to pesticides and metals
  48. Toxicology study of nanoclays adsorbed with the antimicrobial peptide nisin on Caenorhabditis elegans
  49. Occupational risk assessment of exposure to metals in chrome plating workers
  50. Biomarkers of exposure, effect, and susceptibility in occupational exposure to traffic‐related air pollution: A review
  51. Oral Treatment of Spontaneously Hypertensive Rats with Captopril-Surface Functionalized Furosemide-Loaded Multi-Wall Lipid-Core Nanocapsules
  52. A SIMPLE AND SENSITIVE LC-MS/MS METHOD FOR THE DETERMINATION OF S-PHENYLMERCAPTURIC ACID IN HUMAN URINE
  53. In vitro toxic evaluation of two gliptins and their main impurities of synthesis
  54. Evaluation of immunological, inflammatory, and oxidative stress biomarkers in gasoline station attendants
  55. Melatonin-loaded lipid-core nanocapsules protect against lipid peroxidation caused by paraquat through increased SOD expression in Caenorhabditis elegans
  56. Novel coumarins active against Trypanosoma cruzi and toxicity assessment using the animal model Caenorhabditis elegans
  57. Piperazine designer drugs elicit toxicity in the alternative in vivo model Caenorhabditis elegans
  58. Toxic elements in packed red blood cells from smoker donors: a risk for paediatric transfusion?
  59. Reprotoxicity of glyphosate-based formulation in Caenorhabditis elegans is not due to the active ingredient only
  60. Hepatoprotective activity of Verbena litoralis, Verbena montevidensis and their main iridoid, brasoside
  61. In vitro cardiotoxicity evaluation of graphene oxide
  62. Estimation of total arsenic contamination and exposure in Brazilian rice and infant cereals
  63. Evaluation of hematological, biochemical parameters and thiol enzyme activity in chrome plating workers
  64. Inflammatory and oxidative stress biomarkers at protein and molecular levels in workers occupationally exposed to crystalline silica
  65. Ethyl 4-(2-fluorophenyl)-6-methyl-2-thioxo-1-(p-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate
  66. Exposure to environment chemicals and its possible role in endocrine disruption of children from a rural area
  67. Combination of energy drink and alcohol and its associated toxicity
  68. The role of B7 costimulation in benzene immunotoxicity and its potential association with cancer risk
  69. Inflammatory and oxidative stress parameters as potential early biomarkers for silicosis
  70. Energy drink and alcohol combination leads to kidney and liver alterations in rats
  71. Synthesis and in vitro Evaluation of 1,2,3-triazole-4-chloromethylcoumarins with Antioxidant Activity
  72. In vitro toxicity assessment of rivaroxaban degradation products and kinetic evaluation to decay process
  73. Protective effect of Uncaria tomentosa extract against oxidative stress and genotoxicity induced by glyphosate-Roundup® using zebrafish (Danio rerio) as a model
  74. Are metals and pyrene levels additional factors playing a pivotal role in air pollution-induced inflammation in taxi drivers?
  75. Effect of N-1 arylation of monastrol on kinesin Eg5 inhibition in glioma cell lines
  76. Microcystin-LR exposure induces oxidative damage in Caenorhabditis elegans: Protective effect of lutein extracted from marigold flowers
  77. Adenosine reduces reactive oxygen species and interleukin-8 production by Trichomonas vaginalis-stimulated neutrophils
  78. Ozone generated by air purifier in low concentrations: friend or foe?
  79. Long-Term Excessive Selenium Supplementation Induces Hypertension in Rats
  80. Interference of single walled carbon nanotubes (SWCNT) in the measurement of lipid peroxidation in aquatic organisms through TBARS assay
  81. Biomonitoring of gasoline station attendants exposed to benzene: Effect of gender
  82. DNA damage in the elderly is associated with 5-MTHF levels: a pro-oxidant activity
  83. Environmental exposure and effects on health of children from a tobacco-producing region
  84. Association between inflammation processes, DNA damage, and exposure to environmental pollutants
  85. Acute toxicity evaluation of polycyclic aromatic hydrocarbons (PAHs) present in asphalt fumes in the alternative model Caenorhabditis elegans
  86. Blood levels of manganese and mercury and effects on kidney and cognitive function in children environmentally exposed from Southern Brazil
  87. Protective effects of melatonin-loaded lipid-core nanocapsules against paraquat damage in the alternative in vivo model Caenorhabditis elegans
  88. Polyphenol-rich food general and on pregnancy effects: a review
  89. Associations among environmental exposure to manganese, neuropsychological performance, oxidative damage and kidney biomarkers in children
  90. Trichomonas vaginalis NTPDase and ecto-5′-nucleotidase hydrolyze guanine nucleotides and increase extracellular guanosine levels under serum restriction
  91. Gender differences in biochemical markers and oxidative stress of rats after 28 days oral exposure to a mixture used for weight loss containing p-synephrine, ephedrine, salicin, and caffeine
  92. Evaluation of potential acute cardiotoxicity of biodegradable nanocapsules in rats by intravenous administration
  93. Combining the Pharmacophore Features of Coumarins and 1,4-Substituted 1,2,3-Triazoles to Design New Acetylcholinesterase Inhibitors: Fast and Easy Generation of 4-Methylcoumarins/1,2,3-triazoles Conjugates via Click Chemistry
  94. Polarimetry as an Analytical Method to Quantify Limonene-Loaded Nanoemulsions.
  95. Protective effects of melatonin-loaded lipid-core nanocapsules on paraquat-induced cytotoxicity and genotoxicity in a pulmonary cell line
  96. Effects of genetic polymorphisms on antioxidant status and concentrations of the metals in the blood of riverside Amazonian communities co-exposed to Hg and Pb
  97. Relationship between blood metals and inflammation in taxi drivers
  98. Haloperidol-loaded lipid-core polymeric nanocapsules reduce DNA damage in blood and oxidative stress in liver and kidneys of rats
  99. Early hematological and immunological alterations in gasoline station attendants exposed to benzene
  100. Behavioral and dopaminergic damage induced by acute iron toxicity in Caenorhabditis elegans
  101. Do poly(epsilon-caprolactone) lipid-core nanocapsules induce oxidative or inflammatory damage after in vivo subchronic treatment?
  102. Cognitive deficits and ALA-D-inhibition in children exposed to multiple metals
  103. Relationship between Inflammation and Oxidative Stress and Cognitive Decline in the Institutionalized Elderly
  104. New Insights into the Chemistry and Antioxidant Activity of Coumarins
  105. Liver δ-Aminolevulinate Dehydratase Activity is Inhibited by Neonicotinoids and Restored by Antioxidant Agents
  106. Are Delta-Aminolevulinate Dehydratase Inhibition and Metal Concentrations Additional Factors for the Age-Related Cognitive Decline?
  107. Evaluation of Toxic Metals and Essential Elements in Children with Learning Disabilities from a Rural Area of Southern Brazil
  108. Fatty Acid Status and Its Relationship to Cognitive Decline and Homocysteine Levels in the Elderly
  109. Urinary 1-Hydroxypyrene is Associated with Oxidative Stress and Inflammatory Biomarkers in Acute Myocardial Infarction
  110. Nitric oxide and reactive species are modulated in the polyphenol-induced ductus arteriosus constriction in pregnant sheep
  111. Evaluation of genotoxicity in workers exposed to benzene and atmospheric pollutants
  112. Atherosclerotic process in taxi drivers occupationally exposed to air pollution and co-morbidities
  113. EXPERIMENTAL CONSTRICTION OF FETAL DUCTUS ARTERIOSUS, OXIDATIVE STRESS, AND POLYPHENOL EXCRETION AFTER MATERNAL POLYPHENOL-RICH DIET IN LATE PREGNANCY
  114. Subchronic Oral Administration of Benzo[a]pyrene Impairs Motor and Cognitive Behavior and Modulates S100B Levels and MAPKs in Rats
  115. In vitro effect of genistein on DNA damage in leukocytes from mucopolysaccharidosis IVA patients
  116. In vivo toxicological evaluation of polymeric nanocapsules after intradermal administration
  117. Methionine Stimulates Motor Impairment And Cerebellar Mercury Deposition in Methylmercury-Exposed Mice
  118. Polymorphisms in glutathione-related genes modify mercury concentrations and antioxidant status in subjects environmentally exposed to methylmercury
  119. Biomarkers of occupational exposure to air pollution, inflammation and oxidative damage in taxi drivers
  120. Polymeric Nanoparticles: In Vivo Toxicological Evaluation, Cardiotoxicity, and Hepatotoxicity
  121. Evaluation of biochemical and redox parameters in rats fed with corn grown in soil amended with urban sewage sludge
  122. Exogenous and endogenous antioxidants attenuate the lipid peroxidation in workers occupationally exposed to paints
  123. Genotoxicity and oxidative stress in gasoline station attendants
  124. The Antioxidant Activity of Coumarins and Flavonoids
  125. The Antioxidant Activity of Coumarins and Flavonoids
  126. Development and validation of a food frequency questionnaire for consumption of polyphenol-rich foods in pregnant women
  127. A LC-UV method to assay N-acetylcysteine without derivatization: analyses of pharmaceutical products
  128. Plasma Malondialdehyde Levels and Risk Factors for the Development of Chronic Complications in Type 2 Diabetic Patients on Insulin Therapy
  129. Acute and Subchronic Toxicity Evaluation of Poly(ɛ-Caprolactone) Lipid-Core Nanocapsules in Rats
  130. Evaluation of lipid damage related to pathological and physiological conditions
  131. Evaluation of oxidative biomarkers in rats fed with corn cropped in different concentrations of urban sludge
  132. Evaluation of GlutathioneS-transferaseGSTM1andGSTT1Polymorphisms and Methylmercury Metabolism in an Exposed Amazon Population
  133. Simultaneous quantification of lycopene, β-carotene, retinol and α -tocopherol in plasma after a simple extraction procedure: stability study and application to human volunteers
  134. Fetal ductal constriction caused by maternal ingestion of green tea in late pregnancy: an experimental study
  135. Evaluation of genotoxicity and oxidative damage in painters exposed to low levels of toluene
  136. Evaluation of the Antioxidant Capacity of Synthesized Coumarins
  137. Ischemia modified albumin and carbonyl protein as potential biomarkers of protein oxidation in hemodialysis
  138. Analysis of the NTPDase and ecto-5'-nucleotidase profiles in serum-limited Trichomonas vaginalis
  139. Aminolevulinate dehydratase (δ-ALA-D) as marker protein of intoxication with metals and other pro-oxidant situations
  140. Response to the letter of Dr. A. Nersesyan
  141. Designer drugs: aspectos analíticos e biológicos
  142. Letter to editor
  143. Reduction of butyrylcholinesterase activity in plasma from patients with disorders of propionate metabolism is prevented by treatment with L-carnitine and protein restriction
  144. Quantificação sérica de vitamina C por CLAE-UV e estudo de estabilidade
  145. Reversal of fetal ductal constriction after maternal restriction of polyphenol-rich foods: an open clinical trial
  146. Evaluation of toxic effects of a diet containing fish contaminated with methylmercury in rats mimicking the exposure in the Amazon riverside population
  147. The relationships between exogenous and endogenous antioxidants with the lipid profile and oxidative damage in hemodialysis patients
  148. Blood thioredoxin reductase activity, oxidative stress and hematological parameters in painters and battery workers: relationship with lead and cadmium levels in blood
  149. Experimental evidence of oxidative stress in plasma of homocystinuric patients: A possible role for homocysteine
  150. N-acetylcysteine on oxidative damage in diabetic rats
  151. Acute toxicological evaluation of lipid-core nanocapsules
  152. Subchronic toxicological evaluation of lipid-core nanocapsules
  153. Association among Microalbuminuria and Oxidative Stress Biomarkers in Patients with Type 2 Diabetes
  154. Ischemia-modified albumin as an oxidative stress biomarker in obesity
  155. Occupational risk assessment of oxidative stress and genotoxicity in workers exposed to paints during a working week
  156. Presence of synthetic pharmaceuticals as adulterants in slimming phytotherapeutic formulations and their analytical determination
  157. Evidence that l-Carnitine and Selenium Supplementation Reduces Oxidative Stress in Phenylketonuric Patients
  158. Possíveis efeitos do cobre sanguíneo sobre parâmetros hematológicos em idosas
  159. A new method for the simultaneous determination of 1,4-benzodiazepines and amfepramone as adulterants in phytotherapeutic formulations by voltammetry
  160. Effects of low-level exposure to xenobiotics present in paints on oxidative stress in workers
  161. Determination of synthetic pharmaceuticals in phytotherapeutics by capillary zone electrophoresis with contactless conductivity detection (CZE-C4D)
  162. Aluminum Loading in Preterm Neonates Revisited
  163. Could selenium and omega-3 modify the oxidative damage promoted by methylmercury at low doses in rats?
  164. Intoxicação em cães e gatos: diagnóstico toxicológico empregando cromatografia em camada delgada e cromatografia líquida de alta pressão com detecção ultravioleta em amostras estomacais
  165. Aluminum Content in Intravenous Solutions for Administration to Neonates
  166. Sub-Chronic Exposure to Methylmercury at Low Levels Decreases Butyrylcholinesterase Activity in Rats
  167. Mercury exposure and oxidative stress in communities of the Brazilian Amazon
  168. Determination of sodium, potassium, calcium, magnesium, zinc, and iron in emulsified egg samples by flame atomic absorption spectrometry
  169. Determination of metallic contaminants in human recombinant erythropoietin (EPO) formulations by adsorptive cathodic stripping voltammetry and UV photo-decomposition of samples
  170. Subchronic toxicity of Citrus aurantium L. (Rutaceae) extract and p-synephrine in mice
  171. Presence of p-synephrine in teas commercialized in Porto Alegre (RS/Brazil)
  172. Low level and sub-chronic exposure to methylmercury induces hypertension in rats: nitric oxide depletion and oxidative damage as possible mechanisms
  173. The plasma retinol levels as pro-oxidant/oxidant agents in haemodialysis patients
  174. Importance of the lipid peroxidation biomarkers and methodological aspects FOR malondialdehyde quantification
  175. Sensitivity of young rats to nicotine exposure: Physiological and biochemical parameters
  176. Chronic hyperhomocysteinemia alters antioxidant defenses and increases DNA damage in brain and blood of rats: Protective effect of folic acid
  177. Low levels of methylmercury induce DNA damage in rats: protective effects of selenium
  178. Role of medication in the level of aluminium in the blood of chronic haemodialysis patients
  179. Selenium minimize DNA damage in rats exposed to low dose of methylmercury
  180. Low levels of methylmercury induce DNA damage in rats: protective effects of selenium
  181. Concentrations of p-synephrine in fruits and leaves of Citrus species (Rutaceae) and the acute toxicity testing of Citrus aurantium extract and p-synephrine
  182. Screening for in vivo (anti)estrogenic activity of ephedrine and p-synephrine and their natural sources Ephedra sinica Stapf. (Ephedraceae) and Citrus aurantium L. (Rutaceae) in rats
  183. The influence of the hemodialysis treatment time under oxidative stress biomarkers in chronic renal failure patients
  184. Tissue digestion for aluminum determination in experimental animal studies
  185. Butyrylcholinesterase activity is reduced in haemodialysis patients: Is there association with hyperhomocysteinemia and/or oxidative stress?
  186. Influence of chronic exercise on reserpine-induced oxidative stress in rats: Behavioral and antioxidant evaluations
  187. Prenatal methylmercury exposure hampers glutathione antioxidant system ontogenesis and causes long-lasting oxidative stress in the mouse brain
  188. Quantification of reduced glutathione by HPLC-UV in erythrocytes of hemodialysis patients
  189. Effect of astaxanthin on kidney function impairment and oxidative stress induced by mercuric chloride in rats
  190. Avaliação da estabilidade do marcador plasmático do estresse oxidativo: malondialdeído
  191. Quantificação simultânea de indicadores biológicos de exposição a solventes orgânicos por cromatografia líquida de alta eficiência
  192. Determinação voltamétrica de metais em águas e fluidos biológicos empregando mineralização de amostras com radiação ultravioleta
  193. The influence of the serum vitamin C levels on oxidative stress biomarkers in elderly women
  194. Os riscos e danos nas intoxicações por paraquat em animais domésticos
  195. Quantificação laboratorial de cobre sérico por espectrofotometria Vis comparável à espectrometria de absorção atômica com chama
  196. Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: A comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates
  197. Human erythrocyte δ-aminolevulinate dehydratase activity and oxidative stress in hemodialysis patients
  198. Influência de desproteinizantes ácidos na quantificação da glutationa reduzida eritrocitária por CLAE-UV
  199. Independency of myocardial stunning of endothelial stunning?
  200. Reduction in β-myosin heavy chains in stunned myocardium as assessed by nondenaturing gel electrophoresis
  201. Lactational exposure to inorganic mercury: Evidence of neurotoxic effects
  202. Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography–visible detection
  203. Voltammetric behavior of amfepramone (diethylpropion) at the hanging mercury drop electrode and its analytical determination in pharmaceutical formulations
  204. Ion-exchange and potentiometric characterization of Al–cystine and Al–cysteine complexes
  205. Drugs as a hidden source of aluminium for chronic renal patients
  206. Cerebellar thiol status and motor deficit after lactational exposure to methylmercury
  207. Aspectos gerais e diagnóstico clinicolaboratorial da intoxicação por paraquat
  208. Simultaneous Determination of Cadmium, Copper, Lead and Zinc in Amino Acid Parenteral Nutrition Solutions by Anodic Stripping Voltammetry and Sample Digestion by UV Irradiation
  209. Fisiopatologia da deficiência de vitamina B12 e seu diagnóstico laboratorial
  210. Effect of Slaughter Method on Postmortem Changes of Grass Carp ( Ctenopharyngodon idella ) Stored in Icesti
  211. Ciclosporina A e tacrolimus: uma revisão
  212. Determination of thiamine in blood serum and urine by high-performance liquid chromatography with direct injection and post-column derivatization
  213. Comparison of ultrafiltration and solid phase extraction for the separation of free and protein-bound serum copper for the Wilson's disease diagnosis
  214. 466 Hydroxyl peroxide and peroxynitrite contribute differently to the ischemia-reperfusion injury in the rabbit myocardium
  215. Electrophoretic Separation of Ventricular Myosin Isoenzymes Using a Native Polyacrylamide Minigel System
  216. Das isolierte Kaninchenherz: ein Vergleich zwischen fünf Varianten
  217. Contribution of the raw material to the aluminum contamination in parenterals
  218. Influence of the glass packing on the contamination of pharmaceutical products by aluminum. Part I: Salts, glucose, heparin and albumin
  219. Determination of Nickel, Manganese, Copper and Zinc in Blood Serum by Atomic Absorption Spectrometry after Deproteinization by Microwave Irradiation
  220. Polarographic determination of cyanide as nickelcyano complex in blood plasma after selective extraction in a methylene blue impregnated polyethylene column
  221. Deproteinization of blood serum by acid treatment and microwave irradiation for the determinationof aluminium by electrothermal atomicabsorption spectrometry
  222. O problema da contaminação na determinação de traços de alumínio
  223. Liquid Chromatography With Ultraviolet Absorbance Detection of Ethylenethiourea in Blood Serum After Microwave Irradiation as an Auxiliary Cleanup Step