Professor Sang Yup Lee

All Stories

1. 
   Biohybrid CO 2 electrolysis for the direct synthesis of polyesters from CO 2

   Article • Proceedings of the National Academy of Sciences, March 2023, Proceedings of the National Academy of Sciences

   Professor Sang Yup Lee

2. 
   Computational prediction of interactions between Paxlovid and prescription drugs

   Article • Proceedings of the National Academy of Sciences, March 2023, Proceedings of the National Academy of Sciences

   Professor Sang Yup Lee

3. 
   An operator-based expression toolkit for Bacillus subtilis enables fine-tuning of gene expression and biosynthetic pathway regulation

   Article • Proceedings of the National Academy of Sciences, March 2022, Proceedings of the National Academy of Sciences

   Professor Sang Yup Lee

4. 
   Three-dimensional label-free visualization and quantification of polyhydroxyalkanoates in individual bacterial cell in its native state

   Article • Proceedings of the National Academy of Sciences, July 2021, Proceedings of the National Academy of Sciences

   Professor Sang Yup Lee

5. 
   Drugs repurposed for COVID-19 by virtual screening of 6,218 drugs and cell-based assay

   Article • Proceedings of the National Academy of Sciences, July 2021, Proceedings of the National Academy of Sciences

   Professor Sang Yup Lee

6. 
   DeepTFactor: A deep learning-based tool for the prediction of transcription factors

   Article • Proceedings of the National Academy of Sciences, December 2020, Proceedings of the National Academy of Sciences

   Professor Sang Yup Lee

7. 
   Glutaric acid production by systems metabolic engineering of an l -lysine–overproducing Corynebacterium glutamicum

   Article • Proceedings of the National Academy of Sciences, November 2020, Proceedings of the National Academy of Sciences

   Professor Sang Yup Lee

8. 
   Metabolic engineering of Escherichia coli for the enhanced production of L-tyrosine

   Article • Biotechnology and Bioengineering, July 2018, Wiley

   Professor Sang Yup Lee

9. 
   Production of ethylene glycol from xylose by metabolically engineered Escherichia coli

   Article • AIChE Journal, July 2018, Wiley

   Professor Sang Yup Lee

10. 
    Synthetic Biology for Natural Compounds

    Article • Biochemistry, June 2018, American Chemical Society (ACS)

    Professor Sang Yup Lee

11. 
    Metabolomics for industrial fermentation

    Article • Bioprocess and Biosystems Engineering, June 2018, Springer Science + Business Media

    Professor Sang Yup Lee

12. 
    Recombinant Escherichia coli as a biofactory for various single- and multi-element nanomaterials

    Article • Proceedings of the National Academy of Sciences, May 2018, Proceedings of the National Academy of Sciences

    Professor Sang Yup Lee

13. 
    Deep learning improves prediction of drug–drug and drug–food interactions

    Article • Proceedings of the National Academy of Sciences, April 2018, Proceedings of the National Academy of Sciences

    Professor Sang Yup Lee

14. 
    Genome Variations of Evolved Escherichia coli ET8 With a Rhodopsin-Based Phototrophic Metabolism

    Article • Biotechnology Journal, March 2018, Wiley

    Professor Sang Yup Lee

15. 
    Developing a piggyBac Transposon System and Compatible Selection Markers for Insertional Mutagenesis and Genome Engineering in Yarrowia lipolytica

    Article • Biotechnology Journal, March 2018, Wiley

    Professor Sang Yup Lee

16. 
    Recent Trends in Nanomaterials-Based Colorimetric Detection of Pathogenic Bacteria and Viruses

    Article • Small Methods, March 2018, Wiley

    Professor Sang Yup Lee

17. 
    Filling the Gaps in the Kirromycin Biosynthesis: Deciphering the Role of Genes Involved in Ethylmalonyl-CoA Supply and Tailoring Reactions

    Article • Scientific Reports, February 2018, Nature

    Professor Sang Yup Lee

18. 
    Membrane engineering via trans-unsaturated fatty acids production improves succinic acid production in Mannheimia succiniciproducens

    Article • Journal of Industrial Microbiology & Biotechnology, January 2018, Springer Science + Business Media

    Professor Sang Yup Lee

19. 
    Structural insight into molecular mechanism of poly(ethylene terephthalate) degradation

    Article • Nature Communications, January 2018, Nature

    Professor Sang Yup Lee

20. 
    Characterisation of the antibacterial properties of the recombinant phage endolysins AP50-31 and LysB4 as potent bactericidal agents against Bacillus anthracis

    Article • Scientific Reports, January 2018, Nature

    Professor Sang Yup Lee

21. 
    One-step fermentative production of aromatic polyesters from glucose by metabolically engineered Escherichia coli strains

    Article • Nature Communications, January 2018, Nature

    Professor Sang Yup Lee

22. 
    Engineering tunable biosensors for monitoring putrescine in Escherichia coli

    Article • Biotechnology and Bioengineering, January 2018, Wiley

    Professor Sang Yup Lee

23. 
    Metabolic Engineering of Microorganisms for the Production of Natural Compounds

    Article • Advanced Biosystems, December 2017, Wiley

    Professor Sang Yup Lee

24. 
    Production of 5-aminovaleric acid in recombinant Corynebacterium glutamicum strains from a Miscanthus hydrolysate solution prepared by a newly developed Miscanthus hydrolysis process

    Article • Bioresource Technology, December 2017, Elsevier

    Professor Sang Yup Lee

25. 
    Toward Systems Metabolic Engineering of Streptomycetes for Secondary Metabolites Production

    Article • Biotechnology Journal, November 2017, Wiley

    Professor Sang Yup Lee

26. 
    Framework and resource for more than 11,000 gene-transcript-protein-reaction associations in human metabolism

    Article • Proceedings of the National Academy of Sciences, October 2017, Proceedings of the National Academy of Sciences

    Professor Sang Yup Lee

27. 
    Recent advances in systems metabolic engineering tools and strategies

    Article • Current Opinion in Biotechnology, October 2017, Elsevier

    Professor Sang Yup Lee

28. 
    Biosynthesis of 2-Hydroxyacid-Containing Polyhydroxyalkanoates by Employing butyryl-CoA Transferases in Metabolically Engineered Escherichia coli

    Article • Biotechnology Journal, September 2017, Wiley

    Professor Sang Yup Lee

29. 
    Formic acid as a secondary substrate for succinic acid production by metabolically engineered Mannheimia succiniciproducens

    Article • Biotechnology and Bioengineering, September 2017, Wiley

    Professor Sang Yup Lee

30. 
    Charge and dielectric effects of biomolecules on electrical characteristics of nanowire FET biosensors

    Article • Applied Physics Letters, September 2017, American Institute of Physics

    Professor Sang Yup Lee

31. 
    Development of gold nanoparticle-aptamer-based LSPR sensing chips for the rapid detection of Salmonella typhimurium in pork meat

    Article • Scientific Reports, August 2017, Nature

    Professor Sang Yup Lee

32. 
    Holographic deep learning for rapid optical screening of anthrax spores

    Article • Science Advances, August 2017, American Association for the Advancement of Science

    Professor Sang Yup Lee

33. 
    Systems metabolic engineering as an enabling technology in accomplishing sustainable development goals

    Article • Microbial Biotechnology, July 2017, Wiley

    Professor Sang Yup Lee

34. 
    Surrogate strains of human pathogens for field release

    Article • Bioengineered, July 2017, Taylor & Francis

    Professor Sang Yup Lee

35. 
    CRISPR/Cas9-coupled recombineering for metabolic engineering of Corynebacterium glutamicum

    Article • Metabolic Engineering, July 2017, Elsevier

    Professor Sang Yup Lee

36. 
    Dissemination of antibiotic resistance genes from antibiotic producers to pathogens

    Article • Nature Communications, June 2017, Nature

    Professor Sang Yup Lee

37. 
    Biotransformation of p-xylene into terephthalic acid by engineered Escherichia coli

    Article • Nature Communications, May 2017, Nature

    Professor Sang Yup Lee

38. 
    Metabolic engineering of Escherichia coli for the production of four-, five- and six-carbon lactams

    Article • Metabolic Engineering, May 2017, Elsevier

    Professor Sang Yup Lee

39. 
    Engineering the xylose-catabolizing Dahms pathway for production of poly(d -lactate-co -glycolate) and poly(d -lactate-co -glycolate-co -d -2-hydroxybutyrate) in Escherichia coli

    Article • Microbial Biotechnology, April 2017, Wiley

    Professor Sang Yup Lee

40. 
    Systems approach to characterize the metabolism of liver cancer stem cells expressing CD133

    Article • Scientific Reports, April 2017, Nature

    Professor Sang Yup Lee

41. 
    Construction of Bacillus thuringiensis Simulant Strains Suitable for Environmental Release

    Article • Applied and Environmental Microbiology, March 2017, ASM Journals

    Professor Sang Yup Lee

42. 
    Metabolic engineering for the microbial production of marine bioactive compounds

    Article • Biotechnology Advances, March 2017, Elsevier

    Professor Sang Yup Lee

43. 
    Current state and applications of microbial genome-scale metabolic models

    Article • Current Opinion in Systems Biology, March 2017, Elsevier

    Professor Sang Yup Lee

44. 
    Industrial Biotechnology

    Article • January 2017, Wiley

    Professor Volker F Wendisch, Professor Sang Yup Lee

45. 
    Genome analysis of a hyper acetone-butanol-ethanol (ABE) producing Clostridium acetobutylicum BKM19

    Article • Biotechnology Journal, January 2017, Wiley

    Professor Sang Yup Lee

46. 
    Metabolic engineering of Mannheimia succiniciproducens for succinic acid production based on elementary mode analysis with clustering

    Article • Biotechnology Journal, January 2017, Wiley

    Professor Sang Yup Lee

47. 
    Controllable gold-capped nanoporous anodic alumina chip for label-free, specific detection of bacterial cells

    Article • RSC Advances, January 2017, Royal Society of Chemistry

    Professor Sang Yup Lee

48. 
    Metabolic engineering of the genus Clostridium for butanol production

    Article • The Korean Journal of Microbiology, December 2016, The Microbiological Society of Korea

    Professor Sang Yup Lee

49. 
    Production of succinic acid by metabolically engineered microorganisms

    Article • Current Opinion in Biotechnology, December 2016, Elsevier

    Professor Sang Yup Lee

50. 
    In vivo synthesis of europium selenide nanoparticles and related cytotoxicity evaluation of human cells

    Article • Enzyme and Microbial Technology, December 2016, Elsevier

    Professor Sang Yup Lee

51. 
    Structure and function of the N-terminal domain of Ralstonia eutropha polyhydroxyalkanoate synthase, and the proposed structure and mechanisms of the whole enzyme

    Article • Biotechnology Journal, November 2016, Wiley

    Professor Sang Yup Lee

52. 
    Crystal structure of Ralstonia eutropha polyhydroxyalkanoate synthase C-terminal domain and reaction mechanisms

    Article • Biotechnology Journal, November 2016, Wiley

    Professor Sang Yup Lee

53. 
    Homo-succinic acid production by metabolically engineered Mannheimia succiniciproducens

    Article • Metabolic Engineering, November 2016, Elsevier

    Professor Sang Yup Lee

54. 
    Systematic engineering of TCA cycle for optimal production of a four-carbon platform chemical 4-hydroxybutyric acid in Escherichia coli

    Article • Metabolic Engineering, November 2016, Elsevier

    Professor Sang Yup Lee

55. 
    The antiSMASH database, a comprehensive database of microbial secondary metabolite biosynthetic gene clusters

    Article • Nucleic Acids Research, October 2016, Oxford University Press (OUP)

    Professor Sang Yup Lee

56. 
    Biosynthesis of poly(2-hydroxyisovalerate-co-lactate) by metabolically engineeredEscherichia coli

    Article • Biotechnology Journal, September 2016, Wiley

    Professor Sang Yup Lee

57. 
    Efficient gene knockdown inClostridium acetobutylicumby synthetic small regulatory RNAs

    Article • Biotechnology and Bioengineering, August 2016, Wiley

    Professor Sang Yup Lee

58. 
    CRISPR Technologies for Bacterial Systems: Current Achievements and Future Directions

    Article • Biotechnology Advances, August 2016, Elsevier

    Professor Sang Yup Lee

59. 
    Stable and enhanced gene expression in Clostridium acetobutylicum using synthetic untranslated regions with a stem-loop

    Article • Journal of Biotechnology, July 2016, Elsevier

    Professor Sang Yup Lee

60. 
    Combining metabolic engineering and biocompatible chemistry for high-yield production of homo-diacetyl and homo-( S , S )-2,3-butanediol

    Article • Metabolic Engineering, July 2016, Elsevier

    Professor Sang Yup Lee

61. 
    Single Walled Carbon Nanotube-Based Electrical Biosensor for the Label-Free Detection of Pathogenic Bacteria

    Article • Journal of Nanoscience and Nanotechnology, June 2016, American Scientific Publishers

    Professor Sang Yup Lee

62. 
    Highly selective production of succinic acid by metabolically engineered Mannheimia succiniciproducens and its efficient purification

    Article • Biotechnology and Bioengineering, April 2016, Wiley

    Professor Sang Yup Lee

63. 
    Metabolic Engineering of Escherichia coli for the Production of 3-Hydroxypropionic Acid and Malonic Acid through β-Alanine Route

    Article • ACS Synthetic Biology, March 2016, American Chemical Society (ACS)

    Professor Sang Yup Lee

64. 
    One-step fermentative production of poly(lactate-co-glycolate) from carbohydrates in Escherichia coli

    Article • Nature Biotechnology, March 2016, Nature

    Professor Sang Yup Lee

65. 
    Enzymatic formation of carbohydrate rings catalyzed by single-walled carbon nanotubes

    Article • Bioprocess and Biosystems Engineering, March 2016, Springer Science + Business Media

    Professor Sang Yup Lee

66. 
    Systems Metabolic Engineering of Escherichia coli

    Article • EcoSal Plus, January 2016, ASM Journals

    Professor Sang Yup Lee

67. 
    Electro-triggering and electrochemical monitoring of dopamine exocytosis from a single cell by using ultrathin electrodes based on Au nanowires

    Article • Nanoscale, January 2016, Royal Society of Chemistry

    Professor Sang Yup Lee

68. 
    Bioengineering – Use What You Know

    Article • ChemViews, January 2016, Wiley

    Professor Sang Yup Lee

69. 
    Optical Biosensors for the Detection of Pathogenic Microorganisms

    Article • Trends in Biotechnology, January 2016, Elsevier

    Professor Sang Yup Lee

70. 
    EDITOR’S LETTER

    Article • Asia-Pacific Biotech News, January 2016, World Scientific Pub Co Pte Lt

    Professor Sang Yup Lee

71. 
    Biosynthesis of poly(2-hydroxybutyrate-co-lactate) in metabolically engineered Escherichia coli

    Article • Biotechnology and Bioprocess Engineering, January 2016, Springer Science + Business Media

    Professor Sang Yup Lee

72. 
    Metabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites

    Article • Natural Product Reports, January 2016, Royal Society of Chemistry

    Professor Sang Yup Lee

73. 
    Bio-based production of monomers and polymers by metabolically engineered microorganisms

    Article • Current Opinion in Biotechnology, December 2015, Elsevier

    Professor Sang Yup Lee

74. 
    Recent Advances in Biobutanol Production

    Article • Industrial Biotechnology, December 2015, Mary Ann Liebert Inc

    Professor Sang Yup Lee

75. 
    Recent advances in microbial production of fuels and chemicals using tools and strategies of systems metabolic engineering

    Article • Biotechnology Advances, November 2015, Elsevier

    Professor Sang Yup Lee

76. 
    Flux-sum analysis identifies metabolite targets for strain improvement

    Article • BMC Systems Biology, October 2015, Springer Science + Business Media

    Professor Sang Yup Lee

77. 
    Do genome-scale models need exact solvers or clearer standards?

    Article • Molecular Systems Biology, October 2015, EMBO

    Professor Sang Yup Lee, Jun.-Prof. Dr. Andreas Dräger

78. 
    Systems strategies for developing industrial microbial strains

    Article • Nature Biotechnology, October 2015, Nature

    Professor Sang Yup Lee

79. 
    Redox-switch regulatory mechanism of thiolase from Clostridium acetobutylicum

    Article • Nature Communications, September 2015, Nature

    Professor Sang Yup Lee

80. 
    CRISPR-Cas9 Based Engineering of Actinomycetal Genomes

    Article • ACS Synthetic Biology, September 2015, American Chemical Society (ACS)

    Professor Sang Yup Lee

81. 
    Editorial:Biotechnology Journalbrings more than biotechnology

    Article • Biotechnology Journal, September 2015, Wiley

    Professor Sang Yup Lee

82. 
    Label-Free and Real-Time Detection of Avian Influenza Using Nanowire Field Effect Transistors

    Article • Journal of Biomedical Nanotechnology, September 2015, American Scientific Publishers

    Professor Sang Yup Lee

83. 
    Advances in microbial biosynthesis of metal nanoparticles

    Article • Applied Microbiology and Biotechnology, August 2015, Springer Science + Business Media

    Professor Sang Yup Lee

84. 
    Metabolic engineering of Escherichia coli for the production of 1,3-diaminopropane, a three carbon diamine

    Article • Scientific Reports, August 2015, Nature

    Professor Sang Yup Lee

85. 
    Combining rational metabolic engineering and flux optimization strategies for efficient production of fumaric acid

    Article • Applied Microbiology and Biotechnology, July 2015, Springer Science + Business Media

    Professor Sang Yup Lee

86. 
    In Memoriam of Prof. Bernard Witholt

    Article • Biotechnology Journal, July 2015, Wiley

    Professor Sang Yup Lee

87. 
    Metabolic engineering of Escherichia coli for the production of 3-aminopropionic acid

    Article • Metabolic Engineering, July 2015, Elsevier

    Professor Sang Yup Lee

88. 
    antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

    Article • Nucleic Acids Research, May 2015, Oxford University Press (OUP)

    Professor Sang Yup Lee

89. 
    Multispot array combined with S1 nuclease-mediated elimination of unpaired nucleotides

    Article • BioChip Journal, April 2015, Springer Science + Business Media

    Professor Sang Yup Lee

90. 
    Development of rice bran treatment process and its use for the synthesis of polyhydroxyalkanoates from rice bran hydrolysate solution

    Article • Bioresource Technology, April 2015, Elsevier

    Professor Sang Yup Lee

91. 
    Development of a portable biosensor system for pesticide detection on a metal chip surface integrated with wireless communication

    Article • Food Science and Biotechnology, April 2015, Springer Science + Business Media

    Professor Sang Yup Lee

92. 
    How to set up collaborations between academia and industrial biotech companies

    Article • Nature Biotechnology, March 2015, Nature

    Prof Jack T Pronk, Professor Sang Yup Lee

93. 
    A systems approach to traditional oriental medicine

    Article • Nature Biotechnology, March 2015, Nature

    Professor Sang Yup Lee

94. 
    Reconstruction of genome-scale human metabolic models using omics data

    Article • Integrative Biology, March 2015, Oxford University Press (OUP)

    Professor Sang Yup Lee

95. 
    Design of homo-organic acid producing strains using multi-objective optimization

    Article • Metabolic Engineering, March 2015, Elsevier

    Professor Sang Yup Lee

96. 
    Biorefineries for the production of top building block chemicals and their derivatives

    Article • Metabolic Engineering, March 2015, Elsevier

    Professor Sang Yup Lee

97. 
    Transcriptomic analysis of Corynebacterium glutamicum in the response to the toxicity of furfural present in lignocellulosic hydrolysates

    Article • Process Biochemistry, March 2015, Elsevier

    Professor Sang Yup Lee

98. 
    Human genes with a greater number of transcript variants tend to show biological features of housekeeping and essential genes

    Article • Molecular BioSystems, January 2015, Royal Society of Chemistry

    Professor Sang Yup Lee

99. 
    Aptamer-functionalized localized surface plasmon resonance sensor for the multiplexed detection of different bacterial species

    Article • Talanta, January 2015, Elsevier

    Professor Sang Yup Lee

100. 
     Metabolic engineering of antibiotic factories: new tools for antibiotic production in actinomycetes

     Article • Trends in Biotechnology, January 2015, Elsevier

     Professor Sang Yup Lee

101. 
     Editorial: Methods and Advances - Biotech progress for science and our daily lives

     Article • Biotechnology Journal, January 2015, Wiley

     Professor Sang Yup Lee

102. 
     Synthetic Biology of Hydrophobic Polymer Production

     Article • January 2015, Springer Science + Business Media

     Professor Sang Yup Lee

103. 
     Metabolic engineering of clostridia for the production of chemicals

     Article • Biofuels Bioproducts and Biorefining, December 2014, Wiley

     Professor Sang Yup Lee

104. 
     Establishment of a biosynthesis pathway for (R)-3-hydroxyalkanoates in recombinant Escherichia coli

     Article • Korean Journal of Chemical Engineering, December 2014, Springer Science + Business Media

     Professor Sang Yup Lee

105. 
     Applications of genome-scale metabolic network model in metabolic engineering

     Article • Journal of Industrial Microbiology & Biotechnology, December 2014, Springer Science + Business Media

     Professor Sang Yup Lee

106. 
     Metabolic engineering of microorganisms for the production of L-arginine and its derivatives

     Article • Microbial Cell Factories, December 2014, Springer Science + Business Media

     Professor Sang Yup Lee

107. 
     Metabolic engineering ofRalstonia eutrophafor the production of polyhydroxyalkanoates from sucrose

     Article • Biotechnology and Bioengineering, October 2014, Wiley

     Professor Sang Yup Lee

108. 
     Metabolic engineering ofCorynebacterium glutamicumfor the production of L-ornithine

     Article • Biotechnology and Bioengineering, September 2014, Wiley

     Professor Sang Yup Lee

109. 
     The CpxRA Two-Component System is Involved in the Maintenance of the Integrity of the Cell Envelope in the Rumen Bacterium Mannheimia succiniciproducens

     Article • Current Microbiology, September 2014, Springer Science + Business Media

     Professor Sang Yup Lee

110. 
     High-level conversion ofL-lysine into 5-aminovalerate that can be used for nylon 6,5 synthesis

     Article • Biotechnology Journal, September 2014, Wiley

     Professor Sang Yup Lee

111. 
     Metabolic Engineering of Microorganisms for the Production of Higher Alcohols

     Article • mBio, September 2014, ASM Journals

     Professor Sang Yup Lee

112. 
     Genome engineering and gene expression control for bacterial strain development

     Article • Biotechnology Journal, August 2014, Wiley

     Professor Sang Yup Lee

113. 
     Metabolic engineering of Corynebacterium glutamicum for L-arginine production

     Article • Nature Communications, August 2014, Nature

     Professor Sang Yup Lee

114. 
     Editorial: Biotechnology as an enabling technology and much more

     Article • Biotechnology Journal, August 2014, Wiley

     Professor Sang Yup Lee

115. 
     Biosynthesis of single nanoparticles using various metal binding proteins

     Article • New Biotechnology, July 2014, Elsevier

     Professor Sang Yup Lee

116. 
     Metabolic Engineering of E. coli for the production of alkanes

     Article • New Biotechnology, July 2014, Elsevier

     Professor Sang Yup Lee

117. 
     Effects of introducing heterologous pathways on microbial metabolism with respect to metabolic optimality

     Article • Biotechnology and Bioprocess Engineering, July 2014, Springer Science + Business Media

     Professor Sang Yup Lee

118. 
     Metabolic engineering of Clostridium acetobutylicum for highly selective butyric acid production

     Article • New Biotechnology, July 2014, Elsevier

     Professor Sang Yup Lee

119. 
     Bio-based production of chemicals, fuels and materials by metabolically engineered microorganisms

     Article • New Biotechnology, July 2014, Elsevier

     Professor Sang Yup Lee

120. 
     Metabolic engineering of Clostridium acetobutylicum for butyric acid production with high butyric acid selectivity

     Article • Metabolic Engineering, May 2014, Elsevier

     Professor Sang Yup Lee

121. 
     Multiplex electrical detection of avian influenza and human immunodeficiency virus with an underlap-embedded silicon nanowire field-effect transistor

     Article • Biosensors and Bioelectronics, May 2014, Elsevier

     Professor Sang Yup Lee

122. 
     Proteomic analyses of the phase transition from acidogenesis to solventogenesis using solventogenic and non-solventogenic Clostridium acetobutylicum strains

     Article • Applied Microbiology and Biotechnology, April 2014, Springer Science + Business Media

     Professor Sang Yup Lee

123. 
     Integrative genome-scale metabolic analysis of Vibrio vulnificus for drug targeting and discovery

     Article • Molecular Systems Biology, April 2014, EMBO

     Professor Sang Yup Lee

124. 
     Development of Metabolic Engineering Strategies for Microbial Platform to Produce Bioplastics

     Article • Applied Chemistry for Engineering, April 2014, The Korean Society of Industrial and Engineering Chemistry

     Professor Sang Yup Lee

125. 
     Cell-Based Method Utilizing Fluorescent Escherichia coli Auxotrophs for Quantification of Multiple Amino Acids

     Article • Analytical Chemistry, March 2014, American Chemical Society (ACS)

     Professor Sang Yup Lee

126. 
     Systems biology and biotechnology of Streptomyces species for the production of secondary metabolites

     Article • Biotechnology Advances, March 2014, Elsevier

     Professor Sang Yup Lee

127. 
     Editorial: Latest methods and advances in biotechnology

     Article • Biotechnology Journal, January 2014, Wiley

     Professor Sang Yup Lee

128. 
     Production of bulk chemicals via novel metabolic pathways in microorganisms

     Article • Biotechnology Advances, November 2013, Elsevier

     Professor Sang Yup Lee

129. 
     Production of 4-hydroxybutyric acid by metabolically engineered Mannheimia succiniciproducens and its conversion to γ-butyrolactone by acid treatment

     Article • Metabolic Engineering, November 2013, Elsevier

     Professor Sang Yup Lee

130. 
     Metabolic engineering of Ralstonia eutropha for the biosynthesis of 2-hydroxyacid-containing polyhydroxyalkanoates

     Article • Metabolic Engineering, November 2013, Elsevier

     Professor Sang Yup Lee

131. 
     Metabolic engineering ofEscherichia colifor the production of phenol from glucose

     Article • Biotechnology Journal, October 2013, Wiley

     Professor Sang Yup Lee

132. 
     Metabolic engineering of Escherichia coli for biosynthesis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) from glucose

     Article • Applied Microbiology and Biotechnology, October 2013, Springer Science + Business Media

     Professor Sang Yup Lee

133. 
     Kinetic model-based feed-forward controlled fed-batch fermentation of Lactobacillus rhamnosus for the production of lactic acid from Arabic date juice

     Article • Bioprocess and Biosystems Engineering, October 2013, Springer Science + Business Media

     Professor Sang Yup Lee

134. 
     Facile Fabrication of Multi-targeted and Stable Biochemical SERS Sensors

     Article • Chemistry - An Asian Journal, October 2013, Wiley

     Professor Sang Yup Lee

135. 
     Microbial production of short-chain alkanes

     Article • Nature, September 2013, Nature

     Professor Sang Yup Lee

136. 
     Metabolic engineering of Clostridium acetobutylicum for enhanced production of butyric acid

     Article • Applied Microbiology and Biotechnology, September 2013, Springer Science + Business Media

     Professor Sang Yup Lee

137. 
     Design and use of synthetic regulatory small RNAs to control gene expression in Escherichia coli

     Article • Nature Protocols, August 2013, Nature

     Professor Sang Yup Lee

138. 
     Editorial: Flavors of international biotechnology

     Article • Biotechnology Journal, July 2013, Wiley

     Professor Sang Yup Lee

139. 
     Rapid one-step inactivation of single or multiple genes inEscherichia coli

     Article • Biotechnology Journal, June 2013, Wiley

     Professor Sang Yup Lee

140. 
     Electrotriggered, Spatioselective, Quantitative Gene Delivery into a Single Cell Nucleus by Au Nanowire Nanoinjector

     Article • Nano Letters, June 2013, American Chemical Society (ACS)

     Professor Sang Yup Lee

141. 
     Metabolic engineering of Escherichia coli for enhanced biosynthesis of poly(3-hydroxybutyrate) based on proteome analysis

     Article • Biotechnology Letters, June 2013, Springer Science + Business Media

     Professor Sang Yup Lee

142. 
     Quantified High-Throughput Screening of Escherichia coli Producing Poly(3-hydroxybutyrate) Based on FACS

     Article • Applied Biochemistry and Biotechnology, June 2013, Springer Science + Business Media

     Professor Sang Yup Lee

143. 
     Microbial production of lactate‐containing polyesters

     Article • Microbial Biotechnology, May 2013, Wiley

     Professor Sang Yup Lee

144. 
     Propionyl-CoA dependent biosynthesis of 2-hydroxybutyrate containing polyhydroxyalkanoates in metabolically engineered Escherichia coli

     Article • Journal of Biotechnology, May 2013, Elsevier

     Professor Sang Yup Lee

145. 
     Metabolic engineering ofClostridium acetobutylicumfor the enhanced production of isopropanol-butanol-ethanol fuel mixture

     Article • Biotechnology Progress, April 2013, Wiley

     Professor Sang Yup Lee

146. 
     Characterization and evaluation of corn steep liquid in acetone-butanol-ethanol production by Clostridium acetobutylicum

     Article • Biotechnology and Bioprocess Engineering, April 2013, Springer Science + Business Media

     Professor Sang Yup Lee

147. 
     Flux-coupled genes and their use in metabolic flux analysis

     Article • Biotechnology Journal, March 2013, Wiley

     Professor Sang Yup Lee

148. 
     Surface engineering for enhancement of sensitivity in an underlap-FET biosensor by control of wettability

     Article • Biosensors and Bioelectronics, March 2013, Elsevier

     Professor Sang Yup Lee

149. 
     Metabolic engineering ofEscherichia colifor the production of fumaric acid

     Article • Biotechnology and Bioengineering, March 2013, Wiley

     Professor Sang Yup Lee

150. 
     Metabolic engineering of Escherichia coli for the production of 5-aminovalerate and glutarate as C5 platform chemicals

     Article • Metabolic Engineering, March 2013, Elsevier

     Professor Sang Yup Lee

151. 
     Acetone-butanol-ethanol production with high productivity usingClostridium acetobutylicumBKM19

     Article • Biotechnology and Bioengineering, February 2013, Wiley

     Professor Sang Yup Lee

152. 
     Construction of homologous and heterologous synthetic sucrose utilizing modules and their application for carotenoid production in recombinant Escherichia coli

     Article • Bioresource Technology, February 2013, Elsevier

     Professor Sang Yup Lee

153. 
     Special issue: current status of bioenergy research

     Article • Bioprocess and Biosystems Engineering, February 2013, Springer Science + Business Media

     Professor Sang Yup Lee

154. 
     Metabolic engineering of Escherichia coli using synthetic small regulatory RNAs

     Article • Nature Biotechnology, January 2013, Nature

     Professor Sang Yup Lee

155. 
     Kinetic Modeling and Simulation

     Article • January 2013, Springer Science + Business Media

     Professor Sang Yup Lee

156. 
     Conservation Analysis

     Article • January 2013, Springer Science + Business Media

     Professor Sang Yup Lee

157. 
     Elementary Mode

     Article • January 2013, Springer Science + Business Media

     Professor Sang Yup Lee

158. 
     WebCell

     Article • January 2013, Springer Science + Business Media

     Professor Sang Yup Lee

159. 
     Surface display of recombinant proteins on Escherichia coli by BclA exosporium of Bacillus anthracis

     Article • Microbial Cell Factories, January 2013, Springer Science + Business Media

     Professor Sang Yup Lee

160. 
     Computational Methods for Strain Design

     Article • January 2013, Elsevier

     Professor Sang Yup Lee

161. 
     Recent advances in production of recombinant spider silk proteins

     Article • Current Opinion in Biotechnology, December 2012, Elsevier

     Professor Sang Yup Lee

162. 
     Effects of nutritional enrichment on the production of acetone-butanol-ethanol (ABE) by Clostridium acetobutylicum

     Article • The Journal of Microbiology, December 2012, Springer Science + Business Media

     Professor Sang Yup Lee

163. 
     Rational Design of Escherichia coli for l -Isoleucine Production

     Article • ACS Synthetic Biology, November 2012, American Chemical Society (ACS)

     Professor Sang Yup Lee

164. 
     Metabolic Engineering and Synthetic Biology in Strain Development

     Article • ACS Synthetic Biology, November 2012, American Chemical Society (ACS)

     Professor Sang Yup Lee

165. 
     Book review -Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology. Second Edition

     Article • Biotechnology Journal, November 2012, Wiley

     Professor Sang Yup Lee

166. 
     Editorial: Biotechnology's impact on sustainable development

     Article • Biotechnology Journal, November 2012, Wiley

     Professor Sang Yup Lee

167. 
     Butanol production from renewable biomass by clostridia

     Article • Bioresource Technology, November 2012, Elsevier

     Professor Sang Yup Lee

168. 
     Advanced bacterial polyhydroxyalkanoates: Towards a versatile and sustainable platform for unnatural tailor-made polyesters

     Article • Biotechnology Advances, November 2012, Elsevier

     Professor Sang Yup Lee

169. 
     Enhanced Butanol Production Obtained by Reinforcing the Direct Butanol-Forming Route in Clostridium acetobutylicum

     Article • mBio, October 2012, ASM Journals

     Professor Sang Yup Lee

170. 
     Facile Functionalization of Colloidal Gold Nanorods by the Specific Binding of an Engineered Protein that Is Preferred over CTAB Bilayers

     Article • ChemPlusChem, October 2012, Wiley

     Professor Sang Yup Lee

171. 
     Metabolic engineering of Escherichia coli for the production of 1-propanol

     Article • Metabolic Engineering, September 2012, Elsevier

     Professor Sang Yup Lee

172. 
     Engineering of microorganisms for the production of biofuels and perspectives based on systems metabolic engineering approaches

     Article • Biotechnology Advances, September 2012, Elsevier

     Professor Sang Yup Lee

173. 
     In Vitro Biosynthesis of Metal Nanoparticles in Microdroplets

     Article • ACS Nano, August 2012, American Chemical Society (ACS)

     Professor Sang Yup Lee

174. 
     Systems biology: the ‘new biotechnology’

     Article • Current Opinion in Biotechnology, August 2012, Elsevier

     Professor Sang Yup Lee

175. 
     Recent advances in reconstruction and applications of genome-scale metabolic models

     Article • Current Opinion in Biotechnology, August 2012, Elsevier

     Professor Sang Yup Lee

176. 
     Nanowire FET Biosensors on a Bulk Silicon Substrate

     Article • IEEE Transactions on Electron Devices, August 2012, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

177. 
     Label-Free Electrochemical Diagnosis of Viral Antigens with Genetically Engineered Fusion Protein

     Article • Sensors, July 2012, MDPI AG

     Professor Chang-Soo Lee, Professor Sang Yup Lee

178. 
     Determination of the Thermodynamically Dominant Metabolic Pathways

     Article • Industrial & Engineering Chemistry Research, July 2012, American Chemical Society (ACS)

     Professor Sang Yup Lee

179. 
     Probing the ArcA regulon in the rumen bacterium Mannheimia succiniciproducens by genome-wide expression profiling

     Article • The Journal of Microbiology, July 2012, Springer Science + Business Media

     Professor Sang Yup Lee

180. 
     Bio-based production of C2-C6 platform chemicals

     Article • Biotechnology and Bioengineering, July 2012, Wiley

     Professor Sang Yup Lee

181. 
     Editorial: NextGen SynBio has arrived...

     Article • Biotechnology Journal, July 2012, Wiley

     Professor Sang Yup Lee

182. 
     Identification of Factors Regulating Escherichia coli 2,3-Butanediol Production by Continuous Culture and Metabolic Flux Analysis

     Article • Journal of Microbiology and Biotechnology, May 2012, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

183. 
     Systems metabolic engineering of microorganisms for natural and non-natural chemicals

     Article • Nature Methods, May 2012, Nature

     Professor Sang Yup Lee

184. 
     Metabolic Profiling of Klebsiella oxytoca: Evaluation of Methods for Extraction of Intracellular Metabolites Using UPLC/Q-TOF-MS

     Article • Applied Biochemistry and Biotechnology, May 2012, Springer Science + Business Media

     Professor Sang Yup Lee

185. 
     Comparative Analysis of Envelope Proteomes in Escherichia coli B and K-12 Strains

     Article • Journal of Microbiology and Biotechnology, April 2012, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

186. 
     Homogeneous Biogenic Paramagnetic Nanoparticle Synthesis Based on a Microfluidic Droplet Generator

     Article • Angewandte Chemie International Edition, April 2012, Wiley

     Professor Sang Yup Lee

187. 
     Deduplication in SSDs: Model and quantitative analysis

     Article • April 2012, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

188. 
     Editorial: Michael Shuler's legacy in biochemical engineering

     Article • Biotechnology Journal, March 2012, Wiley

     Professor Sang Yup Lee

189. 
     An Underlap Channel-Embedded Field-Effect Transistor for Biosensor Application in Watery and Dry Environment

     Article • IEEE Transactions on Nanotechnology, March 2012, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

190. 
     A nanoforest structure for practical surface-enhanced Raman scattering substrates

     Article • Nanotechnology, February 2012, Institute of Physics Publishing

     Professor Sang Yup Lee

191. 
     Editorial: State-of-the-art reviews in industrial biotechnology

     Article • Biotechnology Journal, February 2012, Wiley

     Professor Sang Yup Lee

192. 
     A Dual-Gate Field-Effect Transistor for Label-Free Electrical Detection of Avian Influenza

     Article • BioNanoScience, January 2012, Springer Science + Business Media

     Professor Sang Yup Lee

193. 
     Single-step multiplex detection of toxic metal ions by Au nanowires-on-chip sensor using reporter elimination

     Article • Lab on a Chip, January 2012, Royal Society of Chemistry

     Professor Sang Yup Lee

194. 
     Systems Metabolic Engineering

     Article • January 2012, Springer Science + Business Media

     Professor Sang Yup Lee

195. 
     Genome-Scale Network Modeling

     Article • January 2012, Springer Science + Business Media

     Professor Sang Yup Lee

196. 
     Systems metabolic engineering, industrial biotechnology and microbial cell factories

     Article • Microbial Cell Factories, January 2012, Springer Science + Business Media

     Professor Sang Yup Lee

197. 
     Systems Metabolic Engineering of Escherichia coli for Chemicals, Materials, Biofuels, and Pharmaceuticals

     Article • January 2012, Springer Science + Business Media

     Professor Sang Yup Lee

198. 
     Genome-scale metabolic model of the fission yeast Schizosaccharomyces pombe and the reconciliation of in silico/in vivo mutant growth

     Article • BMC Systems Biology, January 2012, Springer Science + Business Media

     Professor Sang Yup Lee

199. 
     Flux variability scanning based on enforced objective flux for identifying gene amplification targets

     Article • BMC Systems Biology, January 2012, Springer Science + Business Media

     Professor Sang Yup Lee

200. 
     Development of label-free optical diagnosis for sensitive detection of influenza virus with genetically engineered fusion protein

     Article • Talanta, January 2012, Elsevier

     Professor Sang Yup Lee

201. 
     Comparative multi-omics systems analysis of Escherichia coli strains B and K-12

     Article • Genome Biology, January 2012, Springer Science + Business Media

     Professor Sang Yup Lee

202. 
     Editorial: Breaking down the walls to achieve interdisciplinary science and engineering

     Article • Biotechnology Journal, January 2012, Wiley

     Professor Sang Yup Lee

203. 
     Blind source separation of speech and music signals using harmonic frequency dependent independent vector analysis

     Article • Electronics Letters, January 2012, the Institution of Engineering and Technology (the IET)

     Professor Sang Yup Lee

204. 
     Metabolic Engineering of Clostridium acetobutylicum ATCC 824 for Isopropanol-Butanol-Ethanol Fermentation

     Article • Applied and Environmental Microbiology, December 2011, ASM Journals

     Professor Sang Yup Lee

205. 
     An engineered Escherichia coli having a high intracellular level of ATP and enhanced recombinant protein production

     Article • Applied Microbiology and Biotechnology, December 2011, Springer Science + Business Media

     Professor Sang Yup Lee

206. 
     Special issue: bioenergy

     Article • Bioprocess and Biosystems Engineering, December 2011, Springer Science + Business Media

     Professor Sang Yup Lee

207. 
     EDITORIAL

     Article • Asia-Pacific Biotech News, December 2011, World Scientific Pub Co Pte Lt

     Professor Sang Yup Lee

208. 
     Microbial production of building block chemicals and polymers

     Article • Current Opinion in Biotechnology, December 2011, Elsevier

     Professor Sang Yup Lee

209. 
     Metabolic network modeling and simulation for drug targeting and discovery

     Article • Biotechnology Journal, November 2011, Wiley

     Professor Sang Yup Lee

210. 
     Distinct Roles of  -Galactosidase Paralogues of the Rumen Bacterium Mannheimia succiniciproducens

     Article • Journal of Bacteriology, November 2011, ASM Journals

     Professor Sang Yup Lee

211. 
     Biosynthesis of lactate-containing polyesters by metabolically engineered bacteria

     Article • Biotechnology Journal, November 2011, Wiley

     Professor Sang Yup Lee

212. 
     Continuous butanol production with reduced byproducts formation from glycerol by a hyper producing mutant of Clostridium pasteurianum

     Article • Applied Microbiology and Biotechnology, November 2011, Springer Science + Business Media

     Professor Sang Yup Lee

213. 
     Investigation of Size Dependence on Sensitivity for Nanowire FET Biosensors

     Article • IEEE Transactions on Nanotechnology, November 2011, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

214. 
     Editorial: Biotechnology Journal shines the spotlight on ACB-2011

     Article • Biotechnology Journal, November 2011, Wiley

     Professor Sang Yup Lee

215. 
     Construction of Copper Removing Bacteria Through the Integration of Two-Component System and Cell Surface Display

     Article • Applied Biochemistry and Biotechnology, September 2011, Springer Science + Business Media

     Professor Sang Yup Lee

216. 
     Synthesis and application of virus-based hybrid nanomaterials

     Article • Biotechnology and Bioengineering, September 2011, Wiley

     Professor Sang Yup Lee

217. 
     Combining a Nanowire SERRS Sensor and a Target Recycling Reaction for Ultrasensitive and Multiplex Identification of Pathogenic Fungi

     Article • Small, September 2011, Wiley

     Professor Sang Yup Lee

218. 
     DNA capturing machinery through spore-displayed proteins

     Article • Letters in Applied Microbiology, August 2011, Wiley

     Professor Sang Yup Lee

219. 
     Plasmonic Properties of the Multispot Copper-Capped Nanoparticle Array Chip and Its Application to Optical Biosensors for Pathogen Detection of Multiplex DNAs

     Article • Analytical Chemistry, August 2011, American Chemical Society (ACS)

     Professor Sang Yup Lee

220. 
     Biosynthesis of polyhydroxyalkanoates containing 2-hydroxybutyrate from unrelated carbon source by metabolically engineered Escherichia coli

     Article • Applied Microbiology and Biotechnology, August 2011, Springer Science + Business Media

     Professor Sang Yup Lee

221. 
     Butanol production from renewable biomass: Rediscovery of metabolic pathways and metabolic engineering

     Article • Biotechnology Journal, August 2011, Wiley

     Professor Sang Yup Lee

222. 
     Systems metabolic engineering for chemicals and materials

     Article • Trends in Biotechnology, August 2011, Elsevier

     Professor Sang Yup Lee

223. 
     Book review: An Introduction to Molecular Biotechnology: Fundamentals, Methods, and Applications (2nd edition)

     Article • Biotechnology Journal, July 2011, Wiley

     Professor Sang Yup Lee

224. 
     Detection of Single Nucleotide Polymorphisms by a Gold Nanowire-on-Film SERS Sensor Coupled with S1 Nuclease Treatment

     Article • Chemistry - A European Journal, June 2011, Wiley

     Professor Sang Yup Lee

225. 
     A study on the dynamics of the zraP gene expression profile and its application to the construction of zinc adsorption bacteria

     Article • Bioprocess and Biosystems Engineering, June 2011, Springer Science + Business Media

     Professor Sang Yup Lee

226. 
     Graphene-based electrochemical biosensor for pathogenic virus detection

     Article • BioChip Journal, June 2011, Springer Science + Business Media

     Professor Sang Yup Lee

227. 
     Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol

     Article • Nature Methods, May 2011, Nature

     Professor Sang Yup Lee

228. 
     Parameter estimation and dynamic control analysis of central carbon metabolism in Escherichia coli

     Article • Biotechnology and Bioprocess Engineering, April 2011, Springer Science + Business Media

     Professor Sang Yup Lee

229. 
     Genome-wide identification of the subcellular localization of the Escherichia coli B proteome using experimental and computational methods

     Article • PROTEOMICS, February 2011, Wiley

     Professor Sang Yup Lee

230. 
     Directed Self-Assembly of Gold Nanoparticles on Graphene-Ionic Liquid Hybrid for Enhancing Electrocatalytic Activity

     Article • Electroanalysis, February 2011, Wiley

     Professor Sang Yup Lee

231. 
     Quantitative studies of carbohydrate-protein interaction using functionalized bacterial spores in solution and on chips

     Article • Biotechnology and Bioprocess Engineering, February 2011, Springer Science + Business Media

     Professor Sang Yup Lee

232. 
     Dynamic Modeling of Lactic Acid Fermentation Metabolism with Lactococcus lactis

     Article • Journal of Microbiology and Biotechnology, February 2011, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

233. 
     Development of a Point-of-Care Testing Platform With a Nanogap-Embedded Separated Double-Gate Field Effect Transistor Array and Its Readout System for Detection of Avian Influenza

     Article • IEEE Sensors Journal, February 2011, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

234. 
     Escherichia coli W as a new platform strain for the enhanced production of L-Valine by systems metabolic engineering

     Article • Biotechnology and Bioengineering, January 2011, Wiley

     Professor Sang Yup Lee

235. 
     Understanding and engineering of microbial cells based on proteomics and its conjunction with other omics studies

     Article • PROTEOMICS, January 2011, Wiley

     Professor Sang Yup Lee

236. 
     Tailor-made type II Pseudomonas PHA synthases and their use for the biosynthesis of polylactic acid and its copolymer in recombinant Escherichia coli

     Article • Applied Microbiology and Biotechnology, January 2011, Springer Science + Business Media

     Professor Sang Yup Lee

237. 
     Au Nanowire-on-Film SERRS Sensor for Ultrasensitive Hg2+ Detection

     Article • Chemistry - A European Journal, January 2011, Wiley

     Professor Sang Yup Lee

238. 
     The genome sequence of E. coli W (ATCC 9637): comparative genome analysis and an improved genome-scale reconstruction of E. coli

     Article • BMC Genomics, January 2011, Springer Science + Business Media

     Lars K Nielsen, Professor Sang Yup Lee

239. 
     Programmable peptide-directed two dimensional arrays of various nanoparticles on graphene sheets

     Article • Nanoscale, January 2011, Royal Society of Chemistry

     Professor Sang Yup Lee

240. 
     Site-specific immobilization of gold binding polypeptide on gold nanoparticle-coated graphene sheet for biosensor application

     Article • Nanoscale, January 2011, Royal Society of Chemistry

     Professor Sang Yup Lee

241. 
     Development of anaerobically inducible nar promoter expression vectors for the expression of recombinant proteins in Escherichia coli

     Article • Journal of Biotechnology, January 2011, Elsevier

     Dr Jong Hyun Choi, Professor Sang Yup Lee

242. 
     Characterization of a Bacterial Self-Assembly Surface Layer Protein and Its Application as an Electrical Nanobiosensor

     Article • Journal of Nanoscience and Nanotechnology, January 2011, American Scientific Publishers

     Dr Jong Hyun Choi, Professor Sang Yup Lee

243. 
     Long-term continuous adaptation of Escherichia coli to high succinate stress and transcriptome analysis of the tolerant strain

     Article • Journal of Bioscience and Bioengineering, January 2011, Elsevier

     Professor Sang Yup Lee

244. 
     Label-free Electrochemical Biosensor Based on Graphene/Ionic Liquid Nanocomposite for the Detection of Organophosphate Pesticides

     Article • MRS Proceedings, January 2011, Cambridge University Press

     Professor Sang Yup Lee

245. 
     Genome-scale reconstruction and in silico analysis of the Ralstonia eutropha H16 for polyhydroxyalkanoate synthesis, lithoautotrophic growth, and 2-methyl citric acid production

     Article • BMC Systems Biology, January 2011, Springer Science + Business Media

     Professor Sang Yup Lee

246. 
     Framework for network modularization and Bayesian network analysis to investigate the perturbed metabolic network

     Article • BMC Systems Biology, January 2011, Springer Science + Business Media

     Professor Sang Yup Lee

247. 
     Efficient production of polylactic acid and its copolymers by metabolically engineered Escherichia coli

     Article • Journal of Biotechnology, January 2011, Elsevier

     Professor Sang Yup Lee

248. 
     Development of Reflective Biosensor Using Fabrication of Functionalized Photonic Nanocrystals

     Article • Journal of Nanoscience and Nanotechnology, January 2011, American Scientific Publishers

     Professor Sang Yup Lee

249. 
     Application of Metabolic Flux Analysis in Metabolic Engineering

     Article • January 2011, Elsevier

     Professor Sang Yup Lee

250. 
     Metabolic Control

     Article • January 2011, Elsevier

     Professor Sang Yup Lee

251. 
     Organic Acids

     Article • January 2011, Elsevier

     Professor Sang Yup Lee

252. 
     PHA/PHB

     Article • January 2011, Elsevier

     Professor Sang Yup Lee

253. 
     Systems Metabolic Engineering for the Production of Non-innate Chemical Compounds

     Article • January 2011, Elsevier

     Professor Sang Yup Lee

254. 
     Complete Genome Sequence of the Metabolically Versatile Plant Growth-Promoting Endophyte Variovorax paradoxus S110

     Article • Journal of Bacteriology, December 2010, ASM Journals

     Professor Sang Yup Lee

255. 
     Multi-stage high cell continuous fermentation for high productivity and titer

     Article • Bioprocess and Biosystems Engineering, December 2010, Springer Science + Business Media

     Professor Sang Yup Lee

256. 
     Editorial: A big “thank you” to Barbara

     Article • Biotechnology Journal, December 2010, Wiley

     Professor Sang Yup Lee

257. 
     Fed-batch culture of Escherichia coli for L-valine production based on in silico flux response analysis

     Article • Biotechnology and Bioengineering, November 2010, Wiley

     Professor Sang Yup Lee

258. 
     Comparative proteomic and genetic analyses reveal unidentified mutations in Escherichia coli XL1-Blue and DH5α

     Article • FEMS Microbiology Letters, November 2010, Oxford University Press (OUP)

     Professor Sang Yup Lee

259. 
     Systems Metabolic Engineering for Chemicals and Materials

     Article • Journal of Biotechnology, November 2010, Elsevier

     Professor Sang Yup Lee

260. 
     Systems Metabolic Engineering for Chemicals and Materials

     Article • Journal of Biotechnology, November 2010, Elsevier

     Professor Sang Yup Lee

261. 
     Immobilization of genetically engineered fusion proteins on gold-decorated carbon nanotube hybrid films for the fabrication of biosensor platforms

     Article • Journal of Colloid and Interface Science, October 2010, Elsevier

     Professor Sang Yup Lee

262. 
     Metabolic engineering of Escherichia coli for the production of cadaverine: A five carbon diamine

     Article • Biotechnology and Bioengineering, September 2010, Wiley

     Professor Sang Yup Lee

263. 
     Large-Scale Highly Ordered Chitosan-Core Au-Shell Nanopatterns with Plasmonic Tunability: A Top-Down Approach to Fabricate Core-Shell Nanostructures

     Article • Advanced Functional Materials, September 2010, Wiley

     Professor Sang Yup Lee

264. 
     In Vivo Synthesis of Diverse Metal Nanoparticles by Recombinant Escherichia coli

     Article • Angewandte Chemie International Edition, September 2010, Wiley

     Professor Sang Yup Lee

265. 
     A charge pumping technique to identify biomolecular charge polarity using a nanogap embedded biotransistor

     Article • Applied Physics Letters, August 2010, American Institute of Physics

     Professor Sang Yup Lee

266. 
     Development of sucrose-utilizing Escherichia coli K-12 strain by cloning β-fructofuranosidases and its application for l-threonine production

     Article • Applied Microbiology and Biotechnology, August 2010, Springer Science + Business Media

     Lars K Nielsen, Professor Sang Yup Lee

267. 
     Double-Gate Nanowire Field Effect Transistor for a Biosensor

     Article • Nano Letters, August 2010, American Chemical Society (ACS)

     Professor Sang Yup Lee

268. 
     Prediction of metabolic fluxes by incorporating genomic context and flux-converging pattern analyses

     Article • Proceedings of the National Academy of Sciences, August 2010, Proceedings of the National Academy of Sciences

     Professor Sang Yup Lee

269. 
     Editorial: A call for ethical regulation of Genetically Created Organisms (GCOs) beyond GMOs

     Article • Biotechnology Journal, August 2010, Wiley

     Professor Sang Yup Lee

270. 
     Functionalization Effects of Single-Walled Carbon Nanotubes as Templates for the Synthesis of Silica Nanorods and Study of Growing Mechanism of Silica

     Article • ACS Nano, July 2010, American Chemical Society (ACS)

     Professor Sang Yup Lee

271. 
     Native-sized recombinant spider silk protein produced in metabolically engineered Escherichia coli results in a strong fiber

     Article • Proceedings of the National Academy of Sciences, July 2010, Proceedings of the National Academy of Sciences

     Professor Sang Yup Lee

272. 
     Label-free optical diagnosis of hepatitis B virus with genetically engineered fusion proteins

     Article • Talanta, July 2010, Elsevier

     Professor Sang Yup Lee

273. 
     Editorial: Systems biology for biotech applications

     Article • Biotechnology Journal, July 2010, Wiley

     Professor Sang Yup Lee

274. 
     Development of a gene knockout system for Ralstonia eutropha H16 based on the broad-host-range vector expressing a mobile group II intron

     Article • FEMS Microbiology Letters, July 2010, Oxford University Press (OUP)

     Professor Sang Yup Lee

275. 
     In silicogenome-scale metabolic analysis ofPseudomonas putidaKT2440 for polyhydroxyalkanoate synthesis, degradation of aromatics and anaerobic survival

     Article • Biotechnology Journal, June 2010, Wiley

     Professor Sang Yup Lee

276. 
     Extracellular proteome of Aspergillus terreus grown on different carbon sources

     Article • Current Genetics, June 2010, Springer Science + Business Media

     Professor Sang Yup Lee

277. 
     Metabolic pathways and fermentative production of L-aspartate family amino acids

     Article • Biotechnology Journal, June 2010, Wiley

     Professor Sang Yup Lee

278. 
     Construction and optimization of synthetic pathways in metabolic engineering

     Article • Current Opinion in Microbiology, June 2010, Elsevier

     Professor Sang Yup Lee

279. 
     Comprehensive study of a detection mechanism and optimization strategies to improve sensitivity in a nanogap-embedded biotransistor

     Article • Journal of Applied Physics, June 2010, American Institute of Physics

     Professor Sang Yup Lee

280. 
     Solution Chemistry of Self-Assembled Graphene Nanohybrids for High-Performance Flexible Biosensors

     Article • ACS Nano, May 2010, American Chemical Society (ACS)

     Professor Sang Yup Lee

281. 
     Genome-scale metabolic model of methylotrophic yeastPichia pastorisand its use forin silicoanalysis of heterologous protein production

     Article • Biotechnology Journal, May 2010, Wiley

     Professor Sang Yup Lee

282. 
     ChemInform Abstract: Preparation of Optically Active β-Amino Acids from Microbial Polyester Polyhydroxyalkanoates.

     Article • ChemInform, May 2010, Wiley

     Professor Sang Yup Lee

283. 
     Experimental study of the decay K L 0 → π 0 ν ν ¯

     Article • Physical Review D, April 2010, American Physical Society (APS)

     Professor Sang Yup Lee

284. 
     Patterned Multiplex Pathogen DNA Detection by Au Particle-on-Wire SERS Sensor

     Article • Nano Letters, April 2010, American Chemical Society (ACS)

     Professor Sang Yup Lee

285. 
     Carbon sources-dependent carotenoid production in metabolically engineered Escherichia coli

     Article • World Journal of Microbiology and Biotechnology, April 2010, Springer Science + Business Media

     Professor Sang Yup Lee

286. 
     Fabrication of single-walled carbon nanotubes dotted with Au nanocrystals: Potential DNA delivery nanocarriers

     Article • Carbon, April 2010, Elsevier

     Professor Sang Yup Lee

287. 
     DNA microarray for the identification of pathogens causing bloodstream infections

     Article • Expert Review of Molecular Diagnostics, April 2010, Taylor & Francis

     Professor Sang Yup Lee

288. 
     Development of a Glucose Biosensor Using Advanced Electrode Modified by Nanohybrid Composing Chemically Modified Graphene and Ionic Liquid

     Article • Electroanalysis, March 2010, Wiley

     Professor Sang Yup Lee

289. 
     In Silico Identification of Gene Amplification Targets for Improvement of Lycopene Production

     Article • Applied and Environmental Microbiology, March 2010, ASM Journals

     Professor Sang Yup Lee

290. 
     Editorial: Exploring microbes in biotech

     Article • Biotechnology Journal, March 2010, Wiley

     Professor Sang Yup Lee

291. 
     Rapid separation of bacteriorhodopsin using a laminar-flow extraction system in a microfluidic device

     Article • Biomicrofluidics, March 2010, American Institute of Physics

     Professor Sang Yup Lee

292. 
     Metabolite-centric approaches for the discovery of antibacterials using genome-scale metabolic networks

     Article • Metabolic Engineering, March 2010, Elsevier

     Professor Sang Yup Lee

293. 
     Detection of the Most Common Corneal Dystrophies Caused by BIGH3 Gene Point Mutations Using a Multispot Gold-Capped Nanoparticle Array Chip

     Article • Analytical Chemistry, February 2010, American Chemical Society (ACS)

     Dr So Young Yoo, Professor Sang Yup Lee

294. 
     DNA microarray-based identification of bacterial and fungal pathogens in bloodstream infections

     Article • Molecular and Cellular Probes, February 2010, Elsevier

     Professor Sang Yup Lee

295. 
     Data integration and analysis of biological networks

     Article • Current Opinion in Biotechnology, February 2010, Elsevier

     Professor Sang Yup Lee

296. 
     Charge pumping technique to analyze the effect of intrinsically retained charges and extrinsically trapped charges in biomolecules by use of a nanogap embedded biotransistor

     Article • Applied Physics Letters, February 2010, American Institute of Physics

     Professor Sang Yup Lee

297. 
     Biotechnological applications of microbial proteomes

     Article • Journal of Biotechnology, February 2010, Elsevier

     Professor Sang Yup Lee

298. 
     An underlap field-effect transistor for electrical detection of influenza

     Article • Applied Physics Letters, January 2010, American Institute of Physics

     Professor Sang Yup Lee

299. 
     Mannheimia succiniciproducens Phosphotransferase System for Sucrose Utilization

     Article • Applied and Environmental Microbiology, January 2010, ASM Journals

     Professor Sang Yup Lee

300. 
     Microwave-assisted synthesis of highly water-soluble graphene towards electrical DNA sensor

     Article • Nanoscale, January 2010, Royal Society of Chemistry

     Professor Sang Yup Lee

301. 
     Genome-scale metabolic network analysis and drug targeting of multi-drug resistant pathogen Acinetobacter baumannii AYE

     Article • Molecular BioSystems, January 2010, Royal Society of Chemistry

     Professor Sang Yup Lee

302. 
     The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies

     Article • Microbial Cell Factories, January 2010, Springer Science + Business Media

     Professor Sang Yup Lee

303. 
     Prediction of novel synthetic pathways for the production of desired chemicals

     Article • BMC Systems Biology, January 2010, Springer Science + Business Media

     Professor Sang Yup Lee

304. 
     Metabolic engineering ofEscherichia colifor the production of polylactic acid and its copolymers

     Article • Biotechnology and Bioengineering, January 2010, Wiley

     Professor Sang Yup Lee

305. 
     Integration of Systems Biology with Bioprocess Engineering: l-Threonine Production by Systems Metabolic Engineering of Escherichia Coli

     Article • January 2010, Springer Science + Business Media

     Professor Sang Yup Lee

306. 
     Biosynthesis of polylactic acid and its copolymers using evolved propionate CoA transferase and PHA synthase

     Article • Biotechnology and Bioengineering, January 2010, Wiley

     Professor Sang Yup Lee

307. 
     The Effect of Network Density on the DNA-Sensing Performance of Single-Walled Carbon Nanotubes

     Article • The Journal of Physical Chemistry C, December 2009, American Chemical Society (ACS)

     Professor Sang Yup Lee

308. 
     Isolation and genetic manipulation of the antibiotic down-regulatory gene, wblA ortholog for doxorubicin-producing Streptomyces strain improvement

     Article • Applied Microbiology and Biotechnology, December 2009, Springer Science + Business Media

     Professor Sang Yup Lee

309. 
     What's in a name?

     Article • Nature Biotechnology, December 2009, Nature

     Professor Sang Yup Lee

310. 
     Enhanced Display of Lipase on the Escherichia coli Cell Surface, Based on Transcriptome Analysis

     Article • Applied and Environmental Microbiology, November 2009, ASM Journals

     Professor Sang Yup Lee

311. 
     Continuous Production of Succinic Acid Using an External Membrane Cell Recycle System

     Article • Journal of Microbiology and Biotechnology, November 2009, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

312. 
     Nanogap Field-Effect Transistor Biosensors for Electrical Detection of Avian Influenza

     Article • Small, November 2009, Wiley

     Professor Sang Yup Lee

313. 
     Editorial: Biochips and nanobiotechnology

     Article • Biotechnology Journal, November 2009, Wiley

     Professor Sang Yup Lee

314. 
     Bio-based production of chemicals and materials

     Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

     Professor Sang Yup Lee

315. 
     Metabolic engineering of Escherichia coli for the production of large spider dragline silk proteins

     Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

     Professor Sang Yup Lee

316. 
     Metabolic engineering of Escherichia coli for the production of l-isoleucine

     Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

     Professor Sang Yup Lee

317. 
     Label-free optical biosensors for the detection of food toxin and pathogen using multi-spot nanoparticle array chip and fusion proteins

     Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

     Professor Sang Yup Lee

318. 
     Label-free electrochemical biosensor in highly conductive carbon nanotube and gold nanocomplexes

     Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

     Professor Sang Yup Lee

319. 
     In silico perturbation of the effects of H2 and CO2 on the metabolism of a capnophilic bacterium, Mannheimia succiniciproducens

     Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

     Professor Sang Yup Lee

320. 
     In silico analysis of the effects of H2 and CO2 on the metabolism of a capnophilic bacterium Mannheimia succiniciproducens

     Article • Journal of Biotechnology, November 2009, Elsevier

     Professor Sang Yup Lee

321. 
     Improved prediction of metabolic fluxes through genomic context analysis across organisms and stoichiometric analysis of carbon fluxes

     Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

     Professor Sang Yup Lee

322. 
     Constraints-based genome-scale metabolic simulation for systems metabolic engineering

     Article • Biotechnology Advances, November 2009, Elsevier

     Professor Sang Yup Lee

323. 
     Comparative proteomic analysis of four biotechnologically important Escherichia coli strains for rational host selection

     Article • Journal of Bioscience and Bioengineering, November 2009, Elsevier

     Professor Sang Yup Lee

324. 
     Towards Systems Metabolic Engineering of PHA Producers

     Article • October 2009, Springer Science + Business Media

     Professor Sang Yup Lee

325. 
     Fermentative production of branched chain amino acids: a focus on metabolic engineering

     Article • Applied Microbiology and Biotechnology, October 2009, Springer Science + Business Media

     Professor Sang Yup Lee

326. 
     SYSTEMS BIOTECHNOLOGY

     Article • October 2009, World Scientific Pub Co Pte Lt

     Professor Sang Yup Lee

327. 
     Metabolic engineering ofClostridium acetobutylicumM5 for highly selective butanol production

     Article • Biotechnology Journal, October 2009, Wiley

     Professor Sang Yup Lee

328. 
     Editorial: Methods and Advances in Biotech

     Article • Biotechnology Journal, September 2009, Wiley

     Professor Sang Yup Lee

329. 
     Polyhydroxybutyrate microarray for immunodiagnostics and pathogen detections by immobilizing fusion proteins

     Article • New Biotechnology, September 2009, Elsevier

     Professor Sang Yup Lee

330. 
     Metabolite-centric approach using genome-scale metabolic network for drug targeting of pathogens

     Article • New Biotechnology, September 2009, Elsevier

     Professor Sang Yup Lee

331. 
     Identification of sucrose uptake system in Mannheimia succiniciproducens

     Article • New Biotechnology, September 2009, Elsevier

     Professor Sang Yup Lee

332. 
     Editorial: A Korean vision on Green Growth

     Article • Biotechnology Journal, August 2009, Wiley

     Professor Sang Yup Lee

333. 
     Kinetic study on succinic acid and acetic acid formation during continuous cultures of Anaerobiospirillum succiniciproducens grown on glycerol

     Article • Bioprocess and Biosystems Engineering, July 2009, Springer Science + Business Media

     Professor Sang Yup Lee

334. 
     Validation of Metabolic Models

     Article • July 2009, Taylor & Francis

     Professor Sang Yup Lee

335. 
     A self-assembled fusion protein-based surface plasmon resonance biosensor for rapid diagnosis of severe acute respiratory syndrome

     Article • Talanta, July 2009, Elsevier

     Professor Sang Yup Lee

336. 
     Multiobjective flux balancing using the NISE method for metabolic network analysis

     Article • Biotechnology Progress, July 2009, Wiley

     Professor Sang Yup Lee

337. 
     Ho Nam Chang Special Issue: Life of a great biochemical engineer and his life-time contribution to high cell density culture

     Article • Bioprocess and Biosystems Engineering, June 2009, Springer Science + Business Media

     Professor Sang Yup Lee

338. 
     Proteome-based physiological analysis of the metabolically engineered succinic acid producer Mannheimia succiniciproducens LPK7

     Article • Bioprocess and Biosystems Engineering, June 2009, Springer Science + Business Media

     Professor Sang Yup Lee

339. 
     A biomolecular detection method based on charge pumping in a nanogap embedded field-effect-transistor biosensor

     Article • Applied Physics Letters, June 2009, American Institute of Physics

     Professor Sang Yup Lee

340. 
     High-throughput identification of clinically important bacterial pathogens using DNA microarray

     Article • Molecular and Cellular Probes, June 2009, Elsevier

     Dr So Young Yoo, Professor Sang Yup Lee

341. 
     Spore Display Using Bacillus thuringiensis Exosporium Protein InhA

     Article • Journal of Microbiology and Biotechnology, May 2009, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

342. 
     A well-ordered flower-like gold nanostructure for integrated sensors via surface-enhanced Raman scattering

     Article • Nanotechnology, May 2009, Institute of Physics Publishing

     Professor Sang Yup Lee

343. 
     Development of a whole-cell biosensor by cell surface display of a gold-binding polypeptide on the gold surface

     Article • FEMS Microbiology Letters, April 2009, Oxford University Press (OUP)

     Professor Sang Yup Lee

344. 
     Free-flow isoelectric focusing microfluidic device with glass coating by sol–gel methods

     Article • Current Applied Physics, March 2009, Elsevier

     Professor Sang Yup Lee

345. 
     Development of the electrochemical biosensor for organophosphate chemicals using CNT/ionic liquid bucky gel electrode

     Article • Electrochemistry Communications, March 2009, Elsevier

     Professor Sang Yup Lee

346. 
     A putative secreted solute binding protein, SCO6569 is a possible AfsR2-dependent down-regulator of actinorhodin biosynthesis in Streptomyces coelicolor

     Article • Process Biochemistry, March 2009, Elsevier

     Professor Sang Yup Lee

347. 
     Optimization and Scale-Up of Succinic Acid Production by Mannheimia succiniciproducens LPK7

     Article • Journal of Microbiology and Biotechnology, February 2009, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

348. 
     Functional Expression of SAV3818, a Putative TetR-Family Transcriptional Regulatory Gene from Streptomyces avermitilis, Stimulates Antibiotic Production in Streptomyces Species

     Article • Journal of Microbiology and Biotechnology, February 2009, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

349. 
     Editorial: Cell and protein manipulation

     Article • Biotechnology Journal, February 2009, Wiley

     Professor Sang Yup Lee

350. 
     CharacterizingEscherichia coliDH5α growth and metabolism in a complex medium using genome-scale flux analysis

     Article • Biotechnology and Bioengineering, February 2009, Wiley

     Professor Sang Yup Lee

351. 
     Systems Biology and Biotechnology of Escherichia coli

     Article • January 2009, Springer Science + Business Media

     Professor Sang Yup Lee

352. 
     Systems Metabolic Engineering of E. coli

     Article • January 2009, Springer Science + Business Media

     Professor Sang Yup Lee

353. 
     Transcriptome and proteome analyses of adaptive responses to methyl methanesulfonate in Escherichia coli K-12 and ada mutant strains

     Article • BMC Microbiology, January 2009, Springer Science + Business Media

     Professor Sang Yup Lee

354. 
     Potential Application of the Recombinant Escherichia coli-Synthesized Heme as a Bioavailable Iron Source

     Article • Journal of Microbiology and Biotechnology, January 2009, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

355. 
     Metabolic engineering of microorganisms: general strategies and drug production

     Article • Drug Discovery Today, January 2009, Elsevier

     Professor Sang Yup Lee

356. 
     Metabolic engineering ofEscherichia colifor the production of putrescine, a four carbon diamine

     Article • Biotechnology and Bioengineering, January 2009, Wiley

     Professor Sang Yup Lee

357. 
     Elucidation of Multifaceted Evolutionary Processes of Microorganisms by Comparative Genome-Based Analysis

     Article • Journal of Microbiology and Biotechnology, January 2009, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

358. 
     Microarray of DNA–protein complexes on poly-3-hydroxybutyrate surface for pathogen detection

     Article • Analytical and Bioanalytical Chemistry, December 2008, Springer Science + Business Media

     Professor Sang Yup Lee

359. 
     Succinic Acid Production by Anaerobiospirillum succiniciproducens ATCC 29305 Growing on Galactose, Galactose/Glucose, and Galactose/Lactose

     Article • Journal of Microbiology and Biotechnology, November 2008, Korean Society for Microbiology and Biotechnology

     Professor Sang Yup Lee

360. 
     Microbial small heat shock proteins and their use in biotechnology

     Article • Biotechnology Advances, November 2008, Elsevier

     Professor Sang Yup Lee

361. 
     Doping-Free Nanoscale Complementary Carbon-Nanotube Field-Effect Transistors with DNA-Templated Molecular Lithography

     Article • Small, November 2008, Wiley

     Professor Sang Yup Lee

362. 
     Catalytic characteristics of specialty carbon blacks in decomposition of methane for hydrogen production

     Article • Carbon, November 2008, Elsevier

     Professor Sang Yup Lee

363. 
     Proteome-based identification of fusion partner for high-level extracellular production of recombinant proteins inEscherichia coli

     Article • Biotechnology and Bioengineering, October 2008, Wiley

     Dr Jong Hyun Choi, Professor Sang Yup Lee

364. 
     Systems metabolic engineering for the production of chemicals

     Article • Journal of Biotechnology, October 2008, Elsevier

     Professor Sang Yup Lee

365. 
     Towards systems metabolic engineering of microorganisms for amino acid production

     Article • Current Opinion in Biotechnology, October 2008, Elsevier

     Professor Sang Yup Lee

366. 
     Fermentative butanol production by clostridia

     Article • Biotechnology and Bioengineering, October 2008, Wiley

     Professor Sang Yup Lee

367. 
     Augmented robot agent: Enhancing co-presence of the remote participant

     Article • September 2008, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

368. 
     Advanced cleanup process of the free-flow microfluidic device for protein analysis

     Article • Ultramicroscopy, September 2008, Elsevier

     Professor Sang Yup Lee

369. 
     Genome-scale reconstruction and in silico analysis of the Clostridium acetobutylicum ATCC 824 metabolic network

     Article • Applied Microbiology and Biotechnology, August 2008, Springer Science + Business Media

     Professor Sang Yup Lee

370. 
     Application of systems biology for bioprocess development

     Article • Trends in Biotechnology, August 2008, Elsevier

     Professor Sang Yup Lee

371. 
     Characterization of the Arc two-component signal transduction system of the capnophilic rumen bacteriumMannheimia succiniciproducens

     Article • FEMS Microbiology Letters, July 2008, Oxford University Press (OUP)

     Professor Sang Yup Lee

372. 
     Development of a fully integrated microfluidic system for sensing infectious viral disease

     Article • Electrophoresis, June 2008, Wiley

     Professor Sang Yup Lee

373. 
     Diagnosis of Pathogens Using DNA Microarray

     Article • Recent Patents on Biotechnology, June 2008, Bentham Science Publishers

     Professor Sang Yup Lee

374. 
     Metabolic engineering of Escherichia coli for the production of malic acid

     Article • Biochemical Engineering Journal, June 2008, Elsevier

     Professor Sang Yup Lee

375. 
     Biosynthesis of enantiopure (S)-3-hydroxybutyric acid in metabolically engineered Escherichia coli

     Article • Applied Microbiology and Biotechnology, May 2008, Springer Science + Business Media

     Professor Sang Yup Lee

376. 
     Strategies for systems-level metabolic engineering

     Article • Biotechnology Journal, May 2008, Wiley

     Professor Sang Yup Lee

377. 
     Editorial: Biotechnology in Korea – the next generation growth engine

     Article • Biotechnology Journal, May 2008, Wiley

     Professor Sang Yup Lee

378. 
     Hand in hand for a global outreach

     Article • Biotechnology Journal, May 2008, Wiley

     Professor Sang Yup Lee

379. 
     Modeling of batch fermentation kinetics for succinic acid production by Mannheimia succiniciproducens

     Article • Biochemical Engineering Journal, May 2008, Elsevier

     Professor Sang Yup Lee

380. 
     Comparison of the extracellular proteomes ofEscherichia coli B and K-12 strains during high cell density cultivation

     Article • PROTEOMICS, May 2008, Wiley

     Professor Sang Yup Lee

381. 
     Bio-Vision 2016: The second national framework plan for biotechnology promotion in Korea

     Article • Biotechnology Journal, May 2008, Wiley

     Professor Sang Yup Lee, Dr. Eun Sung Kim

382. 
     A Physiology Study ofEscherichia coliOverexpressing Phosphoenolpyruvate Carboxykinase

     Article • Bioscience Biotechnology and Biochemistry, April 2008, Taylor & Francis

     Professor Sang Yup Lee

383. 
     Removal of bovine serum albumin using solid-phase extraction with in-situ polymerized stationary phase in a microfluidic device

     Article • Journal of Chromatography A, April 2008, Elsevier

     Professor Sang Yup Lee

384. 
     Development of chemically defined medium for Mannheimia succiniciproducens based on its genome sequence

     Article • Applied Microbiology and Biotechnology, April 2008, Springer Science + Business Media

     Professor Sang Yup Lee

385. 
     From genome sequence to integrated bioprocess for succinic acid production by Mannheimia succiniciproducens

     Article • Applied Microbiology and Biotechnology, March 2008, Springer Science + Business Media

     Professor Sang Yup Lee

386. 
     Metabolic flux analysis and metabolic engineering of microorganisms

     Article • Molecular BioSystems, January 2008, Royal Society of Chemistry

     Professor Sang Yup Lee

387. 
     Simple micropatterning of biomolecules on a diazoketo-functionalized photoresist

     Article • Journal of Materials Chemistry, January 2008, Royal Society of Chemistry

     Dr So Young Yoo, Professor Sang Yup Lee

388. 
     Proteome-Level Responses ofEscherichia colito Long-Chain Fatty Acids and Use of Fatty Acid Inducible Promoter in Protein Production

     Article • Journal of Biomedicine and Biotechnology, January 2008, Hindawi Publishing Corporation

     Professor Sang Yup Lee

389. 
     New time-scale criteria for model simplification of bio-reaction systems

     Article • BMC Bioinformatics, January 2008, Springer Science + Business Media

     Professor Sang Yup Lee

390. 
     Development of a markerless gene knock-out system for Mannheimia succiniciproducens using a temperature-sensitive plasmid

     Article • FEMS Microbiology Letters, January 2008, Oxford University Press (OUP)

     Professor Sang Yup Lee

391. 
     Effects of dissolved CO2 levels on the growth ofMannheimia succiniciproducens and succinic acid production

     Article • Biotechnology and Bioengineering, December 2007, Wiley

     Professor Sang Yup Lee

392. 
     Systems metabolic engineering of Escherichia coli for L-threonine production

     Article • Molecular Systems Biology, December 2007, EMBO

     Professor Sang Yup Lee

393. 
     Microfluidic cell disruption system employing a magnetically actuated diaphragm

     Article • Electrophoresis, December 2007, Wiley

     Dr Jong Hyun Choi, Professor Sang Yup Lee

394. 
     Transcript and protein level analyses of the interactions among PhoB, PhoR, PhoU and CreC in response to phosphate starvation in Escherichia coli

     Article • FEMS Microbiology Letters, December 2007, Oxford University Press (OUP)

     Professor Sang Yup Lee

395. 
     Recovery of succinic acid produced by fermentation of a metabolically engineered Mannheimia succiniciproducens strain

     Article • Journal of Biotechnology, December 2007, Elsevier

     Professor Sang Yup Lee

396. 
     TheEscherichia coliProteome: Past, Present, and Future Prospects†

     Article • October 2007, ASM Journals

     Professor Sang Yup Lee

397. 
     Adsorption of Pyruvic and Succinic Acid by Amine-Functionalized SBA-15 for the Purification of Succinic Acid from Fermentation Broth

     Article • The Journal of Physical Chemistry C, September 2007, American Chemical Society (ACS)

     Professor Sang Yup Lee

398. 
     Metabolite essentiality elucidates robustness of Escherichia coli metabolism

     Article • Proceedings of the National Academy of Sciences, August 2007, Proceedings of the National Academy of Sciences

     Professor Sang Yup Lee

399. 
     Kinetic study for the extraction of succinic acid with TOA in fermentation broth; effects of pH, salt and contaminated acid

     Article • Biochemical Engineering Journal, August 2007, Elsevier

     Professor Sang Yup Lee

400. 
     Identification of the Cadmium-Inducible Hansenula polymorpha SEO1 Gene Promoter by Transcriptome Analysis and Its Application to Whole-Cell Heavy-Metal Detection Systems

     Article • Applied and Environmental Microbiology, July 2007, ASM Journals

     Professor Sang Yup Lee

401. 
     EcoProDB: the Escherichia coli protein database

     Article • Bioinformatics, July 2007, Oxford University Press (OUP)

     Professor Sang Yup Lee

402. 
     Construction and Characterization of Shuttle Vectors for Succinic Acid-Producing Rumen Bacteria

     Article • Applied and Environmental Microbiology, July 2007, ASM Journals

     Professor Sang Yup Lee

403. 
     Metabolic engineering of Escherichia coli for the production of l -valine based on transcriptome analysis and in silico gene knockout simulation

     Article • Proceedings of the National Academy of Sciences, May 2007, Proceedings of the National Academy of Sciences

     Professor Sang Yup Lee

404. 
     Incorporating metabolic flux ratios into constraint-based flux analysis by using artificial metabolites and converging ratio determinants

     Article • Journal of Biotechnology, May 2007, Elsevier

     Professor Sang Yup Lee

405. 
     Genome-scale analysis of Mannheimia succiniciproducens metabolism

     Article • Biotechnology and Bioengineering, April 2007, Wiley

     Professor Sang Yup Lee

406. 
     Patterning of biomolecules on a biocompatible nonchemically amplified resist

     Article • March 2007, SPIE

     Dr So Young Yoo, Professor Sang Yup Lee

407. 
     Fast and sensitive DNA analysis using changes in the FRET signals of molecular beacons in a PDMS microfluidic channel

     Article • Analytical and Bioanalytical Chemistry, February 2007, Springer Science + Business Media

     Professor Sang Yup Lee

408. 
     Development of a DNA chip for the diagnosis of the most common corneal dystrophies caused by mutations in the  igh3 gene

     Article • British Journal of Ophthalmology, January 2007, BMJ

     Professor Sang Yup Lee

409. 
     A Simple DNA Chip for Diagnosis of Most Common Corneal Dystrophies Caused by ßigh3 Gene Mutations

     Article • January 2007, Institute of Electrical & Electronics Engineers (IEEE)

     Dr So Young Yoo, Professor Sang Yup Lee

410. 
     Proteomic Analysis of a Response to Long-Chain Fatty Acid in Escherichia coli and Its Application

     Article • January 2007, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

411. 
     Novel gene members in the Pho regulon of Escherichia coli

     Article • FEMS Microbiology Letters, November 2006, Oxford University Press (OUP)

     Professor Sang Yup Lee

412. 
     Deciphering bioplastic production

     Article • Nature Biotechnology, October 2006, Nature

     Professor Sang Yup Lee

413. 
     Systems biology as a foundation for genome-scale synthetic biology

     Article • Current Opinion in Biotechnology, October 2006, Elsevier

     Professor Sang Yup Lee

414. 
     Protein Nanopatterns and Biosensors Using Gold Binding Polypeptide as a Fusion Partner

     Article • Analytical Chemistry, October 2006, American Chemical Society (ACS)

     Professor Sang Yup Lee

415. 
     Photonic-crystal-based centrifugal microfluidic biosensors

     Article • September 2006, SPIE

     Professor Sang Yup Lee

416. 
     Simple Patterning of Cells on a Biocompatible Nonchemically Amplified Resist

     Article • Macromolecular Rapid Communications, September 2006, Wiley

     Dr So Young Yoo, Professor Sang Yup Lee

417. 
     High-speed fabrication of patterned colloidal photonic structures in centrifugal microfluidic chips

     Article • August 2006, SPIE

     Professor Sang Yup Lee

418. 
     Production of succinic acid by bacterial fermentation

     Article • Enzyme and Microbial Technology, July 2006, Elsevier

     Professor Sang Yup Lee

419. 
     Optimal Production of Poly-γ-glutamic Acid by Metabolically Engineered Escherichia coli

     Article • Biotechnology Letters, July 2006, Springer Science + Business Media

     Professor Sang Yup Lee

420. 
     The Escherichia coli Proteome: Past, Present, and Future Prospects

     Article • Microbiology and Molecular Biology Reviews, June 2006, ASM Journals

     Professor Sang Yup Lee

421. 
     The proteome ofMannheimia succiniciproducens, a capnophilic rumen bacterium

     Article • PROTEOMICS, June 2006, Wiley

     Professor Sang Yup Lee

422. 
     Effective purification of succinic acid from fermentation broth produced by Mannheimia succiniciproducens

     Article • Process Biochemistry, June 2006, Elsevier

     Professor Sang Yup Lee

423. 
     Commentaries & Analyses — WHITE BIOTECHNOLOGY

     Article • Asia-Pacific Biotech News, May 2006, World Scientific Pub Co Pte Lt

     Professor Sang Yup Lee

424. 
     Polyhydroxyalkanoate chip for the specific immobilization of recombinant proteins and its applications in immunodiagnostics

     Article • Biotechnology and Bioprocess Engineering, April 2006, Springer Science + Business Media

     Professor Sang Yup Lee

425. 
     WebCell: a web-based environment for kinetic modeling and dynamic simulation of cellular networks

     Article • Bioinformatics, March 2006, Oxford University Press (OUP)

     Professor Sang Yup Lee

426. 
     Genome-Based Metabolic Engineering of Mannheimia succiniciproducens for Succinic Acid Production

     Article • Applied and Environmental Microbiology, March 2006, ASM Journals

     Professor Sang Yup Lee

427. 
     Colored Petri net modeling and simulation of signal transduction pathways

     Article • Metabolic Engineering, March 2006, Elsevier

     Professor Sang Yup Lee

428. 
     Production of recombinant proteins by high cell density culture of Escherichia coli

     Article • Chemical Engineering Science, February 2006, Elsevier

     Dr Jong Hyun Choi, Professor Sang Yup Lee

429. 
     DNA microarray-based detection of nosocomial pathogenic Pseudomonas aeruginosa and Acinetobacter baumannii

     Article • Molecular and Cellular Probes, February 2006, Elsevier

     Professor Sang Yup Lee

430. 
     WebCell-script: A web-based script for managing quantitative and qualitative information of cellular networks

     Article • January 2006, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

431. 
     WebCell: An Integrated Environment For Modeling and Simulation of Cellular Networks Online

     Article • January 2006, Institute of Electrical & Electronics Engineers (IEEE)

     Professor Sang Yup Lee

432. 
     Metabolic Engineering of Escherichia coli for Enhanced Production of Succinic Acid, Based on Genome Comparison and In Silico Gene Knockout Simulation

     Article • Applied and Environmental Microbiology, December 2005, ASM Journals

     Professor Sang Yup Lee

433. 
     Cell Surface Display of Lipase in Pseudomonas putida KT2442 Using OprF as an Anchoring Motif and Its Biocatalytic Applications

     Article • Applied and Environmental Microbiology, December 2005, ASM Journals

     Professor Sang Yup Lee

434. 
     Enhanced Proteome Profiling by Inhibiting Proteolysis with Small Heat Shock Proteins

     Article • Journal of Proteome Research, December 2005, American Chemical Society (ACS)

     Professor Sang Yup Lee

435. 
     Solution behavior of synthetic silk peptides and modified recombinant silk proteins

     Article • Applied Physics A, November 2005, Springer Science + Business Media

     Professor Sang Yup Lee

436. 
     Systems-level analysis of genome-scalein silico metabolic models using MetaFluxNet

     Article • Biotechnology and Bioprocess Engineering, October 2005, Springer Science + Business Media

     Professor Sang Yup Lee

437. 
     Graph‐theoretic approach for identifying catalytic or metabolic pathways

     Article • Journal of the Chinese Institute of Engineers, October 2005, Taylor & Francis

     Professor Sang Yup Lee

438. 
     Selective Immobilization of Fusion Proteins on Poly(hydroxyalkanoate) Microbeads

     Article • Analytical Chemistry, September 2005, American Chemical Society (ACS)

     Professor Sang Yup Lee

439. 
     Corrigendum to “In silico analysis of lactate producing metabolic network in Lactococcus lactis” [Enzyme Microb Technol 35 (2004) 654–662]

     Article • Enzyme and Microbial Technology, August 2005, Elsevier

     Professor Sang Yup Lee

440. 
     Global physiological understanding and metabolic engineering of microorganisms based on omics studies

     Article • Applied Microbiology and Biotechnology, July 2005, Springer Science + Business Media

     Professor Sang Yup Lee

441. 
     Systems biotechnology for strain improvement

     Article • Trends in Biotechnology, July 2005, Elsevier

     Professor Sang Yup Lee

442. 
     Micropatterns of Spores Displaying Heterologous Proteins [ J. Am. Chem. Soc . 2004 , 126 , 10512−10513].

     Article • Journal of the American Chemical Society, June 2005, American Chemical Society (ACS)

     Professor Sang Yup Lee

443. 
     MFAML: a standard data structure for representing and exchanging metabolic flux models

     Article • Bioinformatics, May 2005, Oxford University Press (OUP)

     Professor Sang Yup Lee

444. 
     Complementary identification of multiple flux distributions and multiple metabolic pathways

     Article • Metabolic Engineering, May 2005, Elsevier

     Professor Sang Yup Lee

445. 
     Systems Biological Approach for the Production of Various Polyhydroxyalkanoates by Metabolically EngineeredEscherichia coli

     Article • Macromolecular Symposia, April 2005, Wiley

     Professor Sang Yup Lee

446. 
     Engineering of Escherichia coli fatty acid metabolism for the production of polyhydroxyalkanoates

     Article • Enzyme and Microbial Technology, March 2005, Elsevier

     Professor Sang Yup Lee

447. 
     Display of lipase on the cell surface ofEscherichia coli using OprF as an anchor and its application to enantioselective resolution in organic solvent

     Article • Biotechnology and Bioengineering, January 2005, Wiley

     Dr Jong Hyun Choi, Professor Sang Yup Lee

448. 
     Micropatterning proteins on polyhydroxyalkanoate substrates by using the substrate binding domain as a fusion partner

     Article • Biotechnology and Bioengineering, January 2005, Wiley

     Professor Sang Yup Lee

449. 
     Regulatory analysis of amino acid synthesis pathway in Escherichia coli: aspartate family

     Article • Enzyme and Microbial Technology, December 2004, Elsevier

     Professor Sang Yup Lee

450. 
     In silico analysis of lactate producing metabolic network in Lactococcus lactis

     Article • Enzyme and Microbial Technology, December 2004, Elsevier

     Professor Sang Yup Lee

451. 
     Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E

     Article • Enzyme and Microbial Technology, December 2004, Elsevier

     Professor Sang Yup Lee

452. 
     Enantioselective resolution of racemic compounds by cell surface displayed lipase

     Article • Enzyme and Microbial Technology, October 2004, Elsevier

     Dr Jong Hyun Choi, Professor Sang Yup Lee

453. 
     The genome sequence of the capnophilic rumen bacterium Mannheimia succiniciproducens

     Article • Nature Biotechnology, September 2004, Nature

     Professor Sang Yup Lee

454. 
     Display of Bacterial Lipase on the Escherichia coli Cell Surface by Using FadL as an Anchoring Motif and Use of the Enzyme in Enantioselective Biocatalysis

     Article • Applied and Environmental Microbiology, September 2004, ASM Journals

     Professor Sang Yup Lee

455. 
     Micropatterns of Spores Displaying Heterologous Proteins

     Article • Journal of the American Chemical Society, September 2004, American Chemical Society (ACS)

     Professor Sang Yup Lee

456. 
     Covalent Attachment and Hybridization of DNA Oligonucleotides on Patterned Single-Walled Carbon Nanotube Films

     Article • Langmuir, September 2004, American Chemical Society (ACS)

     Professor Sang Yup Lee

457. 
     Enhanced production of succinic acid by metabolically engineeredEscherichia coli with amplified activities of malic enzyme and fumarase

     Article • Biotechnology and Bioprocess Engineering, August 2004, Springer Science + Business Media

     Professor Sang Yup Lee

458. 
     Constitutive production of human leptin by fed-batch culture of recombinant rpoS− Escherichia coli

     Article • Protein Expression and Purification, July 2004, Elsevier

     Dr Jong Hyun Choi, Professor Sang Yup Lee

459. 
     Microarrays of peptides elevated on the protein layer for efficient protein kinase assay

     Article • Analytical Biochemistry, July 2004, Elsevier

     Professor Sang Yup Lee

460. 
     BioSilico: an integrated metabolic database system

     Article • Bioinformatics, June 2004, Oxford University Press (OUP)

     Professor Sang Yup Lee

461. 
     Phylogenetic analysis based on genome-scale metabolic pathway reaction content

     Article • Applied Microbiology and Biotechnology, June 2004, Springer Science + Business Media

     Professor Sang Yup Lee

462. 
     Secretory and extracellular production of recombinant proteins using Escherichia coli

     Article • Applied Microbiology and Biotechnology, June 2004, Springer Science + Business Media

     Dr Jong Hyun Choi, Professor Sang Yup Lee

463. 
     High level production of supra molecular weight poly (3-hydroxybutyrate) by metabolically engineeredEscherichia coli

     Article • Biotechnology and Bioprocess Engineering, June 2004, Springer Science + Business Media

     Professor Sang Yup Lee

464. 
     Development of DNA microarray for pathogen detection

     Article • Biotechnology and Bioprocess Engineering, April 2004, Springer Science + Business Media

     Dr So Young Yoo, Professor Sang Yup Lee

465. 
     Microcontact printing of biotin for selective immobilization of streptavidin-fused proteins and SPR analysis

     Article • Biotechnology and Bioprocess Engineering, April 2004, Springer Science + Business Media

     Professor Sang Yup Lee

466. 
     Micro total analysis system (�-TAS) in biotechnology

     Article • Applied Microbiology and Biotechnology, April 2004, Springer Science + Business Media

     Professor Sang Yup Lee

467. 
     High cell density fed-batch cultivation of Escherichia coli using exponential feeding combined with pH-stat

     Article • Bioprocess and Biosystems Engineering, April 2004, Springer Science + Business Media

     Professor Sang Yup Lee, Professor Beom Soo Kim

468. 
     Fermentative Production of Chemicals That Can Be Used for Polymer Synthesis

     Article • Macromolecular Bioscience, March 2004, Wiley

     Professor Sang Yup Lee

469. 
     Combined Deterministic−Stochastic Approach for Pharmacokinetic Modeling

     Article • Industrial & Engineering Chemistry Research, February 2004, American Chemical Society (ACS)

     Professor Sang Yup Lee

470. 
     Roles and applications of small heat shock proteins in the production of recombinant proteins inEscherichia coli

     Article • Biotechnology and Bioengineering, January 2004, Wiley

     Professor Sang Yup Lee

471. 
     New fadB homologous enzymes and their use in enhanced biosynthesis of medium-chain-length polyhydroxyalkanoates infadB mutantEscherichia coli

     Article • Biotechnology and Bioengineering, January 2004, Wiley

     Professor Sang Yup Lee

472. 
     Multi-product trade-off analysis of E. coli by multiobjective flux balance analysis

     Article • January 2004, Elsevier

     Professor Sang Yup Lee

473. 
     Biosynthesis of Poly(3-hydroxybutyrate- co-3-hydroxyalkanoates) by Metabolically Engineered Escherichia coli Strains

     Article • Applied Biochemistry and Biotechnology, January 2004, Springer Science + Business Media

     Professor Sang Yup Lee

474. 
     Biosynthesis of (R)-3-Hydroxyalkanoic Acids by Metabolically Engineered Escherichia coli

     Article • Applied Biochemistry and Biotechnology, January 2004, Springer Science + Business Media

     Professor Sang Yup Lee

475. 
     Proteome profiling and its use in metabolic and cellular engineering

     Article • PROTEOMICS, December 2003, Wiley

     Professor Sang Yup Lee

476. 
     Organizational and Mutational Analysis of a Complete FR-008/Candicidin Gene Cluster Encoding a Structurally Related Polyene Complex

     Article • Chemistry & Biology, November 2003, Elsevier

     Professor Sang Yup Lee

477. 
     Batch and continuous cultures of Mannheimia succiniciproducens MBEL55E for the production of succinic acid from whey and corn steep liquor

     Article • Bioprocess and Biosystems Engineering, November 2003, Springer Science + Business Media

     Professor Sang Yup Lee

478. 
     MetaFluxNet: the management of metabolic reaction information and quantitative metabolic flux analysis

     Article • Bioinformatics, October 2003, Oxford University Press (OUP)

     Professor Sang Yup Lee

479. 
     Engineering Escherichia coli for Increased Productivity of Serine-Rich Proteins Based on Proteome Profiling

     Article • Applied and Environmental Microbiology, October 2003, ASM Journals

     Professor Sang Yup Lee

480. 
     Identification and Characterization of a New Enoyl Coenzyme A Hydratase Involved in Biosynthesis of Medium-Chain-Length Polyhydroxyalkanoates in Recombinant Escherichia coli

     Article • Journal of Bacteriology, September 2003, ASM Journals

     Professor Sang Yup Lee

481. 
     Enhanced Production of Insulin-Like Growth Factor I Fusion Protein in Escherichia coli by Coexpression of the Down-Regulated Genes Identified by Transcriptome Profiling

     Article • Applied and Environmental Microbiology, August 2003, ASM Journals

     Dr Jong Hyun Choi, Professor Sang Yup Lee

482. 
     In silico prediction and validation of the importance of the Entner-Doudoroff pathway in poly(3-hydroxybutyrate) production by metabolically engineeredEscherichia coli

     Article • Biotechnology and Bioengineering, July 2003, Wiley

     Professor Sang Yup Lee

483. 
     Enrichment of specific monomer in medium-chain-length poly(3-hydroxyalkanoates) by amplification of fadD and fadE genes in recombinant Escherichia coli

     Article • Enzyme and Microbial Technology, July 2003, Elsevier

     Professor Sang Yup Lee

484. 
     Production of Chiral and Other Valuable Compounds from Microbial Polyesters

     Article • ChemInform, June 2003, Wiley

     Professor Sang Yup Lee

485. 
     Enhanced Production of Recombinant Proteins in Escherichia coli by Filamentation Suppression

     Article • Applied and Environmental Microbiology, February 2003, ASM Journals

     Professor Sang Yup Lee

486. 
     Combined transcriptome and proteome analysis ofEscherichia coli during high cell density culture

     Article • Biotechnology and Bioengineering, January 2003, Wiley

     Professor Sang Yup Lee

487. 
     Microbial cell-surface display

     Article • Trends in Biotechnology, January 2003, Elsevier

     Dr Jong Hyun Choi, Professor Sang Yup Lee

488. 
     Article • Biotechnology Letters, January 2003, Springer Science + Business Media

     Professor Sang Yup Lee

489. 
     Fermentative Production of Building Blocks for Chemical Synthesis of Polyesters

     Article • December 2002, Wiley

     Professor Sang Yup Lee

490. 
     Fermentative Production of SCL Polyhydroxyalkanoates (SCL‐PHAs)

     Article • November 2002, Wiley

     Professor Sang Yup Lee

491. 
     Excretion of Human β-Endorphin into Culture Medium by Using Outer Membrane Protein F as a Fusion Partner in Recombinant Escherichia coli

     Article • Applied and Environmental Microbiology, October 2002, ASM Journals

     Professor Sang Yup Lee

492. 
     Metabolic engineering of Escherichia coli for the production of medium-chain-length polyhydroxyalkanoates rich in specific monomers

     Article • FEMS Microbiology Letters, September 2002, Oxford University Press (OUP)

     Professor Sang Yup Lee

493. 
     Isolation and characterization of a new succinic acid-producing bacterium, Mannheimia succiniciproducens MBEL55E, from bovine rumen

     Article • Applied Microbiology and Biotechnology, April 2002, Springer Science + Business Media

     Professor Sang Yup Lee

494. 
     Importance of redox balance on the production of succinic acid by metabolically engineered Escherichia coli

     Article • Applied Microbiology and Biotechnology, March 2002, Springer Science + Business Media

     Professor Sang Yup Lee

495. 
     Economic Aspects of Biopolymer Production

     Article • February 2002, Wiley

     Professor Sang Yup Lee

496. 
     Biotechnological Processes for the Production of Monomers for Subsequent Chemical Polymer Synthesis

     Article • February 2002, Wiley

     Professor Sang Yup Lee

497. 
     Production of Chiral and other Valuable Compounds from Microbial Polyesters

     Article • January 2002, Wiley

     Professor Sang Yup Lee

498. 
     Article • Biotechnology Letters, January 2002, Springer Science + Business Media

     Professor Sang Yup Lee

499. 
     Preparation of optically active β-amino acids from microbial polyester polyhydroxyalkanoates

     Article • Journal of Chemical Research, November 2001, Science Reviews 2000 LTD

     Professor Sang Yup Lee

500. 
     Secretory Production of Human Granulocyte Colony-Stimulating Factor in Escherichia coli

     Article • Protein Expression and Purification, November 2001, Elsevier

     Professor Sang Yup Lee

501. 
     High-level secretory production of human granulocyte-colony stimulating factor by fed-batch culture of recombinant Escherichia coli

     Article • Bioprocess and Biosystems Engineering, November 2001, Springer Science + Business Media

     Professor Sang Yup Lee

502. 
     Industrial scale production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)

     Article • Applied Microbiology and Biotechnology, October 2001, Springer Science + Business Media

     Professor Sang Yup Lee

503. 
     Production of Poly(3-hydroxybutyrate- co -3-hydroxyhexanoate) by Metabolically Engineered Escherichia c oli Strains

     Article • Biomacromolecules, March 2001, American Chemical Society (ACS)

     Professor Sang Yup Lee

504. 
     Production of Microbial Polyester by Fermentation of Recombinant Microorganisms

     Article • January 2001, Springer Science + Business Media

     Professor Sang Yup Lee

505. 
     Article • Biotechnology Letters, January 2001, Springer Science + Business Media

     Professor Sang Yup Lee

506. 
     Metabolic flux analysis for succinic acid production by recombinantEscherichia coli with amplified malic enzyme activity

     Article • Biotechnology and Bioengineering, January 2001, Wiley

     Professor Sang Yup Lee

507. 
     Metabolic and kinetic analysis of poly(3-hydroxybutyrate) production by recombinantEscherichia coli

     Article • Biotechnology and Bioengineering, January 2001, Wiley

     Professor Sang Yup Lee

508. 
     Efficient recovery of ?-poly (glutamic acid) from highly viscous culture broth

     Article • Biotechnology and Bioengineering, January 2001, Wiley

     Professor Sang Yup Lee

509. 
     Production of polyhydroxyalkanoates by fermentation of bacteria

     Article • Macromolecular Symposia, October 2000, Wiley

     Professor Sang Yup Lee

510. 
     Predicting the formation, structure and elastomeric properties of end-linked polymer networks

     Article • Macromolecular Symposia, October 2000, Wiley

     Professor Sang Yup Lee

511. 
     Batch and continuous cultivation of Anaerobiospirillum succiniciproducens for the production of succinic acid from whey

     Article • Applied Microbiology and Biotechnology, July 2000, Springer Science + Business Media

     Professor Sang Yup Lee

512. 
     Preparation of alkyl (R)-(−)-3-hydroxybutyrate by acidic alcoholysis of poly-(R)-(−)-3-hydroxybutyrate

     Article • Enzyme and Microbial Technology, July 2000, Elsevier

     Professor Sang Yup Lee

513. 
     Production of medium-chain-length polyhydroxyalkanoates by high-cell-density cultivation ofPseudomonas putida under phosphorus limitation

     Article • Biotechnology and Bioengineering, May 2000, Wiley

     Professor Sang Yup Lee

514. 
     Bacterial polyhydroxyalkanoates

     Article • Biotechnology and Bioengineering, March 2000, Wiley

     Professor Sang Yup Lee

515. 
     Synthesis of poly-(3-hydroxybutyrate-co-3-hydroxyvalerate) by recombinant Escherichia coli

     Article • Biotechnology and Bioengineering, March 2000, Wiley

     Professor Sang Yup Lee

516. 
     Regulatory effects of cellular nicotinamide nucleotides and enzyme activities on poly(3-hydroxybutyrate) synthesis in recombinant Escherichia coli

     Article • Biotechnology and Bioengineering, March 2000, Wiley

     Professor Sang Yup Lee

517. 
     Secretory production of human leptin inEscherichia coli

     Article • Biotechnology and Bioengineering, February 2000, Wiley

     Professor Sang Yup Lee

518. 
     Secretory production of human leptin in Escherichia coli

     Article • Biotechnology and Bioengineering, February 2000, Wiley

     Professor Sang Yup Lee

519. 
     Production of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) by high-cell-density cultivation ofAeromonas hydrophila

     Article • Biotechnology and Bioengineering, January 2000, Wiley

     Professor Sang Yup Lee

520. 
     Article • Biotechnology Letters, January 2000, Springer Science + Business Media

     Professor Sang Yup Lee

521. 
     Chiral compounds from bacterial polyesters: Sugars to plastics to fine chemicals

     Article • Biotechnology and Bioengineering, November 1999, Wiley

     Professor Sang Yup Lee

522. 
     Effects of medium components on the growth of Anaerobiospirillum succiniciproducens and succinic acid production

     Article • Process Biochemistry, October 1999, Elsevier

     Professor Sang Yup Lee

523. 
     Succinic acid production by Anaerobiospirillum succiniciproducens: effects of the H2/CO2 supply and glucose concentration

     Article • Enzyme and Microbial Technology, June 1999, Elsevier

     Professor Sang Yup Lee

524. 
     Recent advances in polyhydroxyalkanoate production by bacterial fermentation: mini-review

     Article • International Journal of Biological Macromolecules, June 1999, Elsevier

     Professor Sang Yup Lee

525. 
     Secretory Production of Recombinant Protein by a High Cell Density Culture of a Protease Negative Mutant Escherichia coli Strain

     Article • Biotechnology Progress, April 1999, Wiley

     Professor Sang Yup Lee

526. 
     Control of fed-batch fermentations

     Article • Biotechnology Advances, April 1999, Elsevier

     Professor Sang Yup Lee

527. 
     Production and degradation of polyhydroxyalkanoates in waste environment

     Article • Waste Management, April 1999, Elsevier

     Professor Sang Yup Lee

528. 
     Efficient and economical recovery of poly(3-hydroxybutyrate) from recombinantEscherichia coli by simple digestion with chemicals

     Article • Biotechnology and Bioengineering, March 1999, Wiley

     Professor Sang Yup Lee

529. 
     Factors affecting the economics of polyhydroxyalkanoate production by bacterial fermentation

     Article • Applied Microbiology and Biotechnology, January 1999, Springer Science + Business Media

     Professor Sang Yup Lee

530. 
     Article • Biotechnology Letters, January 1999, Springer Science + Business Media

     Professor Sang Yup Lee

531. 
     Development of Recombinant Bacteria for the Degradation of Dibenzothiopheneaa

     Article • Annals of the New York Academy of Sciences, December 1998, Wiley

     Professor Sang Yup Lee

532. 
     Effect of post-induction nutrient feeding strategies on the production of bioadhesive protein inEscherichia coli

     Article • Biotechnology and Bioengineering, November 1998, Wiley

     Professor Sang Yup Lee

533. 
     Improved Production of a Bioadhesive Precursor Protein by Fed-Batch Cultivation of a Recombinant Escherichia coli with a pLysS Vector

     Article • Biotechnology Letters, August 1998, Springer Science + Business Media

     Professor Sang Yup Lee

534. 
     Poly-(3-hydroxybutyrate) production from whey by high-density cultivation of recombinant Escherichia coli

     Article • Applied Microbiology and Biotechnology, July 1998, Springer Science + Business Media

     Professor Sang Yup Lee

535. 
     High cell density culture of metabolically engineeredEscherichia coli for the production of poly(3-hydroxybutyrate) in a defined medium

     Article • Biotechnology and Bioengineering, April 1998, Wiley

     Professor Sang Yup Lee

536. 
     Production of Poly(3-Hydroxybutyrate) by Recombinant Bacteria

     Article • January 1998, Springer Science + Business Media

     Professor Sang Yup Lee

537. 
     Poly(3-hydroxybutyrate) production from xylose by recombinant Escherichia coli

     Article • Bioprocess Engineering, January 1998, Springer Science + Business Media

     Professor Sang Yup Lee

538. 
     Article • Biotechnology Techniques, January 1998, Springer Science + Business Media

     Professor Sang Yup Lee

539. 
     Article • Biotechnology Letters, January 1998, Springer Science + Business Media

     Professor Sang Yup Lee

540. 
     Molecular mass of poly[( R  )-3-hydroxybutyric acid] produced in a recombinant Escherichia coli

     Article • Applied Microbiology and Biotechnology, February 1997, Springer Science + Business Media

     Professor Sang Yup Lee

541. 
     E. coli moves into the plastic age

     Article • Nature Biotechnology, January 1997, Nature

     Professor Sang Yup Lee

542. 
     Process analysis and economic evaluation for Poly(3-hydroxybutyrate) production by fermentation

     Article • Bioprocess Engineering, January 1997, Springer Science + Business Media

     Professor Sang Yup Lee

543. 
     Article • Biotechnology Letters, January 1997, Springer Science + Business Media

     Professor Sang Yup Lee

544. 
     Plastic bacteria? Progress and prospects for polyhydroxyalkanoate production in bacteria

     Article • Trends in Biotechnology, November 1996, Elsevier

     Professor Sang Yup Lee

545. 
     Characteristics of Poly(3-Hydroxybutyric Acid) Synthesis by Recombinant Escherichia colia

     Article • Annals of the New York Academy of Sciences, May 1996, Wiley

     Professor Sang Yup Lee

546. 
     High cell-density culture of Escherichia coli

     Article • Trends in Biotechnology, March 1996, Elsevier

     Professor Sang Yup Lee

547. 
     Bacterial polyhydroxyalkanoates

     Article • Biotechnology and Bioengineering, January 1996, Wiley

     Professor Sang Yup Lee

548. 
     Effect of acetic acid on poly-(3-hydroxybutyrate-CO-3-hydroxyvalerate) synthesis in recombinantEscherichia coli

     Article • Korean Journal of Chemical Engineering, April 1995, Springer Science + Business Media

     Professor Sang Yup Lee

549. 
     Size analysis of poly(3-hydroxybutyric acid) granules produced in recombinant Escherichia coli

     Article • Biotechnology Letters, February 1995, Springer Science + Business Media

     Professor Sang Yup Lee

550. 
     Production of poly(hydroxyalkanoic acid)

     Article • January 1995, Springer Science + Business Media

     Professor Sang Yup Lee

551. 
     Stimulatory effects of amino acids and oleic acid on poly(3-hydroxybutyric acid) synthesis by recombinant Escherichia coli

     Article • Journal of Fermentation and Bioengineering, January 1995, Elsevier

     Professor Sang Yup Lee

552. 
     Comparison of recombinantEscherichia colistrains for synthesis and accumulation of poly-(3-hydroxybutyric acid) and morphological changes

     Article • Biotechnology and Bioengineering, December 1994, Wiley

     Professor Sang Yup Lee

553. 
     Production of poly(3-hydroxybutyric-co-3-hydroxyvaleric acid) by fed-batch culture of Alcaligenes eutrophus with substrate control using on-line glucose analyzer

     Article • Enzyme and Microbial Technology, July 1994, Elsevier

     Professor Sang Yup Lee, Professor Beom Soo Kim

554. 
     Production of Poly(?-Hydroxybutyric Acid) by Recombinant Escherichia colia

     Article • Annals of the New York Academy of Sciences, June 1994, Wiley

     Professor Sang Yup Lee

555. 
     Production of poly(3-hydroxybutyric acid) by fed-batch culture ofAlcaligenes eutrophus with glucose concentration control

     Article • Biotechnology and Bioengineering, April 1994, Wiley

     Professor Sang Yup Lee, Professor Beom Soo Kim

556. 
     Construction of plasmids, estimation of plasmid stability, and use of stable plasmids for the production of poly(3-hydroxybutyric acid) by recombinant Escherichia coli

     Article • Journal of Biotechnology, February 1994, Elsevier

     Professor Sang Yup Lee

557. 
     Production ofBacillus thuringiensis spores in total cell retention culture and two-stage continuous culture using an internal ceramic filter system

     Article • Biotechnology and Bioengineering, November 1993, Wiley

     Professor Sang Yup Lee

558. 
     Direct recovery of intracellular proteins from Candida utilis using reverse micelles in combination with a reducing agent

     Article • Biotechnology Techniques, August 1993, Springer Science + Business Media

     Professor Sang Yup Lee

559. 
     Vector Construction, Transformation, and Gene Amplification in Clostridium acetobutylicum ATCC 824

     Article • Annals of the New York Academy of Sciences, October 1992, Wiley

     Professor Sang Yup Lee

560. 
     Production of poly-?-hydroxybutyrate by fed-batch culture of recombinantEscherichia coli

     Article • Biotechnology Letters, September 1992, Springer Science + Business Media

     Professor Sang Yup Lee, Professor Beom Soo Kim

561. 
     Systems Biotechnology: a New Paradigm in Biotechnology Development

     Article • Springer Science + Business Media

     Professor Sang Yup Lee

562. 
     Systems Metabolic Engineering

     Article • Springer Science + Business Media

     Professor Sang Yup Lee

563. 
     Secretory Production of Therapeutic Proteins in Escherichia coli

     Article • Springer Science + Business Media

     Professor Sang Yup Lee

564. 
     Construction and Applications of Genome-Scalein silico Metabolic Models for Strain Improvement

     Article • Wiley

     Professor Sang Yup Lee