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  1. Activated sputum eosinophils associated with exacerbations in children on mepolizumab
  2. SenNet recommendations for detecting senescent cells in different tissues
  3. Host-microbe multiomic profiling reveals age-dependent immune dysregulation associated with COVID-19 immunopathology
  4. Early cellular and molecular signatures correlate with severity of West Nile virus infection
  5. Proteome Analysis for Inflammation Related to Acute and Convalescent Infection
  6. Data from Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry
  7. Data from Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry
  8. Supplementary Data from Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry
  9. Supplementary Data from Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry
  10. Supplementary Data from Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry
  11. Supplementary Data from Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry
  12. Single-cell immunophenotyping of the skin lesion erythema migrans identifies IgM memory B cells
  13. Using ‘big data’ to disentangle aging and COVID-19
  14. In-Depth Analysis of Genetic Variation Associated with Severe West Nile Viral Disease
  15. Profiling cellular heterogeneity in asthma with single cell multiparameter CyTOF
  16. Molecular MRI of the Immuno-Metabolic Interplay in a Rabbit Liver Tumor Model: A Biomarker for Resistance Mechanisms in Tumor-targeted Therapy?
  17. Single-cell longitudinal analysis of SARS-CoV-2 infection in human airway epithelium
  18. Single Cell Transcriptional Archetypes of Airway Inflammation in Cystic Fibrosis
  19. Single cell immune profiling of dengue virus patients reveals intact immune responses to Zika virus with enrichment of innate immune signatures
  20. Multi‐site reproducibility of a human immunophenotyping assay in whole blood and peripheral blood mononuclear cells preparations using CyTOF technology coupled with Maxpar Pathsetter, an automated data analysis system
  21. Impaired ATM activation in B cells is associated with bone resorption in rheumatoid arthritis
  22. Exploring single-cell data with deep multitasking neural networks
  23. Elevated Activation of Neutrophil Toll-Like Receptors in Patients with Acute Severe Leptospirosis: An Observational Study
  24. A Modified Injector and Sample Acquisition Protocol Can Improve Data Quality and Reduce Inter‐Instrument Variability of the Helios Mass Cytometer
  25. Development of a 2-dimensional atlas of the human kidney with imaging mass cytometry
  26. ImmuneRegulation: a web-based tool for identifying human immune regulatory elements
  27. Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T Cells in Trastuzumab-Treated Patients using Imaging Mass Cytometry
  28. Transcriptomic analysis of human IL‐7 receptor alpha low and high effector memory CD8+ T cells reveals an age‐associated signature linked to influenza vaccine response in older adults
  29. HIPK2 is necessary for type I interferon–mediated antiviral immunity
  30. Aedes aegypti AgBR1 antibodies modulate early Zika virus infection of mice
  31. Dissecting alterations in human CD8+ T cells with aging by high-dimensional single cell mass cytometry
  32. Reduced dynamic range of antiviral innate immune responses in aging
  33. Identification of genetic variants associated with dengue or West Nile virus disease: a systematic review and meta-analysis
  34. SIRT6 Acts as a Negative Regulator in Dengue Virus-Induced Inflammatory Response by Targeting the DNA Binding Domain of NF-κB p65
  35. Age-related changes in expression and signaling of TAM receptor inflammatory regulators in monocytes
  36. Aging impairs both primary and secondary RIG-I signaling for interferon induction in human monocytes
  37. Humanized mouse model supports development, function, and tissue residency of human natural killer cells
  38. Multicohort analysis reveals baseline transcriptional predictors of influenza vaccination responses
  39. Gating mass cytometry data by deep learning
  40. Removal of batch effects using distribution-matching residual networks
  41. West Nile Virus Seroprevalence, Connecticut, USA, 2000–2014
  42. The natural killer cell response to West Nile virus in young and old individuals with or without a prior history of infection
  43. Multiparameter Single Cell Profiling of Airway Inflammatory Cells
  44. Cathelicidin Insufficiency in Patients with Fatal Leptospirosis
  45. Age-related alterations in immune responses to West Nile virus infection
  46. High standards for high dimensional investigations
  47. Coordinated expression of Tryo3, Axl, and Mer receptors in macrophage ontogeny
  48. Mx1 reveals innate pathways to antiviral resistance and lethal influenza disease
  49. Association between high expression macrophage migration inhibitory factor (MIF) alleles and West Nile virus encephalitis
  50. Role of Immune Aging in Susceptibility to West Nile Virus
  51. Leukocyte-specific protein 1 regulates T-cell migration in rheumatoid arthritis
  52. DNA Methylation Regulates the Differential Expression of CX3CR1 on Human IL-7Rαlow and IL-7Rαhigh Effector Memory CD8+ T Cells with Distinct Migratory Capacities to the Fractalkine
  53. Human NK cell repertoire diversity reflects immune experience and correlates with viral susceptibility
  54. Risk factors for West Nile virus infection and disease in populations and individuals
  55. Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing
  56. Imaging Immunosenescence
  57. IL-6 Receptor α Defines Effector Memory CD8+T Cells Producing Th2 Cytokines and Expanding in Asthma
  58. CyTOF supports efficient detection of immune cell subsets from small samples
  59. Systems Immunology Reveals Markers of Susceptibility to West Nile Virus Infection
  60. Editorial overview: Immune senescence: Known knowns and unknown unknowns
  61. Effect of aging on microRNAs and regulation of pathogen recognition receptors
  62. Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling
  63. Reduced bioenergetics and toll-like receptor 1 function in human polymorphonuclear leukocytes in aging
  64. Immune Markers Associated with Host Susceptibility to Infection with West Nile Virus
  65. Innate Immune Responses in the Neutrophils of Community Dwelling and Nursing Home Elders
  66. In Memoriam: Stephen E. Malawista, MD, 1934-2013
  67. ELF4 is critical for induction of type I interferon and the host antiviral response
  68. Age-dependent dysregulation of innate immunity
  69. Functional Polymorphisms in the Gene Encoding Macrophage Migration Inhibitory Factor Are Associated With Gram-Negative Bacteremia in Older Adults
  70. Cytokine Response Signatures in Disease Progression and Development of Severe Clinical Outcomes for Leptospirosis
  71. Identification of Genes Critical for Resistance to Infection by West Nile Virus Using RNA-Seq Analysis
  72. An altered relationship of influenza vaccine-specific IgG responses with T cell immunity occurs with aging in humans
  73. Differential expression analysis for paired RNA-seq data
  74. Semaphorin 7a+Regulatory T Cells Are Associated with Progressive Idiopathic Pulmonary Fibrosis and Are Implicated in Transforming Growth Factor-β1–induced Pulmonary Fibrosis
  75. Impaired Toll-Like Receptor 3-Mediated Immune Responses from Macrophages of Patients Chronically Infected with Hepatitis C Virus
  76. Innate Immune Function by Toll-like Receptors: Distinct Responses in Newborns and the Elderly
  77. West Nile Virus: Biology, Transmission, and Human Infection
  78. Semaphorin 7A Contributes to West Nile Virus Pathogenesis through TGF-β1/Smad6 Signaling
  79. IL-22 Signaling Contributes to West Nile Encephalitis Pathogenesis
  80. Quantitative Imaging of Lineage-specific Toll-like Receptor-mediated Signaling in Monocytes and Dendritic Cells from Small Samples of Human Blood
  81. Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus
  82. Age‐associated elevation in TLR5 leads to increased inflammatory responses in the elderly
  83. Innate immune control of West Nile virus infection
  84. Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks
  85. Dysregulation of human Toll-like receptor function in aging
  86. Impaired Interferon Signaling in Dendritic Cells From Older Donors Infected In Vitro With West Nile Virus
  87. A Paradoxical Role for Neutrophils in the Pathogenesis of West Nile Virus
  88. Anaplasma phagocytophiluminduces actin phosphorylation to selectively regulate gene transcription inIxodes scapularisticks
  89. Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks
  90. Increased TLR4 Expression and Downstream Cytokine Production in Immunosuppressed Adults Compared to Non-Immunosuppressed Adults
  91. Circulating monocytes from systemic sclerosis patients with interstitial lung disease show an enhanced profibrotic phenotype
  92. Age-Associated Decrease in TLR Function in Primary Human Dendritic Cells Predicts Influenza Vaccine Response
  93. IL-10 Signaling Blockade Controls Murine West Nile Virus Infection
  94. Human innate immunosenescence: causes and consequences for immunity in old age
  95. Fusion Loop Peptide of the West Nile Virus Envelope Protein Is Essential for Pathogenesis and Is Recognized by a Therapeutic Cross-Reactive Human Monoclonal Antibody
  96. Inhibition of Neutrophil Function by Two Tick Salivary Proteins
  97. Toll-like Receptor 7 Mitigates Lethal West Nile Encephalitis via Interleukin 23-Dependent Immune Cell Infiltration and Homing
  98. RNA interference screen for human genes associated with West Nile virus infection
  99. Matrix Metalloproteinase 9 Facilitates West Nile Virus Entry into the Brain
  100. Dysregulation of TLR3 Impairs the Innate Immune Response to West Nile Virus in the Elderly
  101. West Nile Virus Attenuates Activation of Primary Human Macrophages
  102. Abrogation of macrophage migration inhibitory factor decreases West Nile virus lethality by limiting viral neuroinvasion
  103. ASC/PYCARD and Caspase-1 Regulate the IL-18/IFN-γ Axis during Anaplasma phagocytophilum Infection
  104. Age-Associated Defect in Human TLR-1/2 Function
  105. Recruitment of Macrophages and Polymorphonuclear Leukocytes in Lyme Carditis
  106. Human Neutrophil Calprotectin Reduces the Susceptibility of Borrelia burgdorferi to Penicillin
  107. TROSPA, an Ixodes scapularis Receptor for Borrelia burgdorferi
  108. Myeloid Differentiation Antigen 88 Deficiency Impairs Pathogen Clearance but Does Not Alter Inflammation in Borrelia burgdorferi-Infected Mice
  109. Tick Saliva Reduces Adherence and Area of Human Neutrophils
  110. Disruption of Ixodes scapularis anticoagulation by using RNA interference
  111. Calprotectin, an Abundant Cytosolic Protein from Human Polymorphonuclear Leukocytes, Inhibits the Growth of Borrelia burgdorferi
  112. Human Phagocytic Cells in the Early Innate Immune Response to Borrelia burgdorferi
  113. Borrelia burgdorferi Are Susceptible to Killing by a Variety of Human Polymorphonuclear Leukocyte Components
  114. Inhibition of Borrelia burgdorferi-Tick Interactions In Vivo by Outer Surface Protein A Antibody
  115. Murine Lyme Disease: No Evidence for Active Immune Down‐Regulation in Resolving or Subclinical Infection
  116. Attachment of Borrelia burgdorferi within Ixodes scapularis mediated by outer surface protein A
  117. Geographic clustering of an outer surface protein A mutant of Borrelia burgdorferi. Possible implications of multiple variants for Lyme disease persistence
  118. Temporal pattern of Borrelia burgdorferi p21 expression in ticks and the mammalian host.
  119. Microbial killing by human neutrophil cytokineplasts: similar suppressive effects of reversible and irreversible inhibitors of nitric oxide synthase
  120. Direct demonstration of antigenic substitution of Borrelia burgdorferi ex vivo: exploration of the paradox of the early immune response to outer surface proteins A and C in Lyme disease.
  121. Fc- And Non-Fc-Mediated Phagocytosis Of Borrelia Burgdorferi By Maerophages
  122. Borrelia burgdorferi and the macrophage: Routine annihilation but occasional haven?
  123. Evidence for reactive nitrogen intermediates in killing of staphylococci by human neutrophil cytoplasts. A new microbicidal pathway for polymorphonuclear leukocytes.
  124. Endocytic and Secretory Repertoire of the Lipid-Loaded Macrophage
  125. Effects of reagent and cell-generated hydrogen peroxide on the properties of low density lipoprotein.
  126. Regulation of mouse oocyte meiotic maturation: Implication of a decrease in oocyte cAMP and protein dephosphorylation in commitment to resume meiosis
  127. Regulation of oocyte maturation in the mouse: Possible roles of intercellular communication, cAMP, and testosterone