All Stories

  1. The proinflammatory cytokines IFN /TNF  increased Chromogranin A-positive neuroendocrine cells in the colonic epithelium.

    Article • Biochemical Journal, August 2016, Portland Press Ltd.

    Porfirio Nava, Dr. Oscar Medina-Contreras

  2. Loss of cortactin causes endothelial barrier dysfunction via disturbed adrenomedullin secretion and actomyosin contractility

    Article • Scientific Reports, June 2016, Nature

    Porfirio Nava

  3. CpAL from C. Perfringens opens the TJ

    Article • Anaerobe, June 2016, Elsevier

    Porfirio Nava

  4. Autophagy induces Akt activation

    Article • Cell Death and Differentiation, February 2016, Nature

    Porfirio Nava, Dr. Oscar Medina-Contreras

  5. Neutrophil interactions with epithelial-expressed ICAM-1 enhances intestinal mucosal wound healing

    Article • Mucosal Immunology, January 2016, Nature

    Porfirio Nava

  6. Experimental Colitis Is Attenuated by Cardioprotective Diet Supplementation That Reduces Oxidative Stress, Inflammation, and Mucosal Damage

    Article • Oxidative Medicine and Cellular Longevity, January 2016, Hindawi Publishing Corporation

    Porfirio Nava

  7. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways

    Article • Experimental Cell Research, November 2015, Elsevier

    Porfirio Nava

  8. Inflammation-induced desmoglein-2 ectodomain shedding compromises the mucosal barrier

    Article • Molecular Biology of the Cell, July 2015, American Society for Cell Biology (ASCB)

    Porfirio Nava

  9. 14-3-3 regulates b catenin transactivation

    Article • Molecular Biology of the Cell, July 2014, American Society for Cell Biology (ASCB)

    Porfirio Nava, Dr. Oscar Medina-Contreras

  10. Galectin-3 Regulates Desmoglein-2 and Intestinal Epithelial Intercellular Adhesion

    Article • Journal of Biological Chemistry, February 2014, American Society for Biochemistry & Molecular Biology (ASBMB)

    Porfirio Nava

  11. Loss of the desmosomal cadherin desmoglein-2 suppresses colon cancer cell proliferation through EGFR signaling

    Article • Oncogene, October 2013, Nature

    Porfirio Nava

  12. Cleavage of cell junction proteins

    Article • Tissue Barriers, April 2013, Taylor & Francis

    Porfirio Nava

  13. Quorum-Sensing Systems LuxS/Autoinducer 2 and Com Regulate Streptococcus pneumoniae Biofilms in a Bioreactor with Living Cultures of Human Respiratory Cells

    Article • Infection and Immunity, February 2013, ASM Journals

    Porfirio Nava

  14. Pathophysiology of nasal polyposis: The role of desmosomal junctions

    Article • American Journal of Rhinology and Allergy, November 2012, Oceanside Publications Inc.

    Porfirio Nava

  15. Compromised Intestinal Epithelial Barrier Induces Adaptive Immune Compensation that Protects from Colitis

    Article • Immunity, September 2012, Elsevier

    Porfirio Nava, Dr. Oscar Medina-Contreras

  16. IFN-γ and TNF-α-induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signaling

    Article • Mucosal Immunology, June 2012, Nature

    Porfirio Nava

  17. The Wnt Antagonist Dkk1 Regulates Intestinal Epithelial Homeostasis and Wound Repair

    Article • Gastroenterology, July 2011, Elsevier

    Porfirio Nava

  18. Characterization of full-length and proteolytic cleavage fragments of desmoglein-2 in native human colon and colonic epithelial cell lines

    Article • Cell Adhesion & Migration, July 2011, Taylor & Francis

    Porfirio Nava

  19. Specialized Intercellular Junctions in Epithelial Cells: The Tight Junction and Desmosome

    Article • May 2011, Wiley

    Porfirio Nava

  20. JAM‐A regulates epithelial proliferation through Akt/β‐catenin signalling

    Article • EMBO Reports, March 2011, EMBO

    Porfirio Nava

  21. Loss of desmocollin-2 confers a tumorigenic phenotype to colonic epithelial cells through activation of Akt/ -catenin signaling

    Article • Molecular Biology of the Cell, February 2011, American Society for Cell Biology (ASCB)

    Porfirio Nava

  22. Ifn gamma inhibits Wnt signaling during colitis.

    Article • Immunity, March 2010, Elsevier

    Professor Arne Skerra, Porfirio Nava

  23. Effects of phenol on barrier function of a human intestinal epithelial cell line correlate with altered tight junction protein localization

    Article • Toxicology and Applied Pharmacology, November 2009, Elsevier

    Porfirio Nava

  24. Dkk-1 Inhibits Intestinal Epithelial Cell Migration by Attenuating Directional Polarization of Leading Edge Cells

    Article • Molecular Biology of the Cell, September 2009, American Society for Cell Biology (ASCB)

    Porfirio Nava

  25. Annexin A1 Regulates Intestinal Mucosal Injury, Inflammation, and Repair

    Article • The Journal of Immunology, September 2008, The American Association of Immunologists

    Porfirio Nava

  26. Formyl Peptide Receptor-1 Activation Enhances Intestinal Epithelial Cell Restitution through Phosphatidylinositol 3-Kinase-Dependent Activation of Rac1 and Cdc42

    Article • The Journal of Immunology, December 2007, The American Association of Immunologists

    Porfirio Nava

  27. JAM-A regulates permeability and inflammation in the intestine in vivo

    Article • The Journal of Experimental Medicine, November 2007, Rockefeller University Press

    Porfirio Nava

  28. Desmoglein-2: A Novel Regulator of Apoptosis in the Intestinal Epithelium

    Article • Molecular Biology of the Cell, August 2007, American Society for Cell Biology (ASCB)

    Porfirio Nava

  29. Critical Role of Tight Junctions in Drug Delivery across Epithelial and Endothelial Cell Layers

    Article • The Journal of Membrane Biology, September 2005, Springer Science + Business Media

    Porfirio Nava

  30. Tight junctions, from tight intercellular seals to sophisticated protein complexes involved in drug delivery, pathogens interaction and cell proliferation

    Article • Advanced Drug Delivery Reviews, April 2005, Elsevier

    Porfirio Nava

  31. The rotavirus surface protein VP8 modulates the gate and fence function of tight junctions in epithelial cells

    Article • Journal of Cell Science, November 2004, The Company of Biologists

    Porfirio Nava

  32. Tight junction proteins

    Article • Progress in Biophysics and Molecular Biology, January 2003, Elsevier

    Porfirio Nava