What is it about?
This publication explains the mechanism that reduces proliferation in intestinal epithelial cells during colitis.
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Why is it important?
Explains how pro-inflammatory cytokines reduce Wnt signaling in colonic epithelium.
Perspectives
Describes how b-catenin signaling is regulated by Akt downstream of IFn gamma receptor.
Porfirio Nava
Centro de investigacion y estudios avanzados del IPN
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This page is a summary of: Interferon-γ Regulates Intestinal Epithelial Homeostasis through Converging β-Catenin Signaling Pathways, Immunity, March 2010, Elsevier,
DOI: 10.1016/j.immuni.2010.03.001.
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