All Stories

  1. The role of extracellular vesicle fusion with target cells in triggering systemic inflammation

    Article • Nature Communications, February 2024, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  2. Identifying biomarkers deciphering sepsis from trauma-induced sterile inflammation and trauma-induced sepsis

    Article • Frontiers in Immunology, January 2024, Frontiers

    prof. dr.-med. Michal Holub

  3. Specific immune responses after BNT162b2 mRNA vaccination and COVID-19 infection

    Article • Frontiers in Immunology, October 2023, Frontiers

    prof. dr.-med. Michal Holub

  4. Elevated regulatory T cells after antibiotic treatment of infectious spondylodiscitis as biomarker of recovery?

    Article • Immunology Letters, April 2023, Elsevier

    prof. dr.-med. Michal Holub

  5. Retrospective Analysis Revealed an April Occurrence of Monkeypox in the Czech Republic

    Article • Viruses, August 2022, MDPI AG

    prof. dr.-med. Michal Holub

  6. Monkeypox and Herpes Simplex Virus Type 2 Coinfection: Case Report of Perianal Lesions in HIV-Positive Patient

    Article • Sexually Transmitted Diseases, August 2022, Wolters Kluwer Health

    prof. dr.-med. Michal Holub

  7. Autoimmunity, cancer and COVID-19 abnormally activate wound healing pathways: critical role of inflammation

    Article • Histochemistry and Cell Biology, July 2022, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  8. Decreased quality of care for Staphylococcus aureus bacteremia during the COVID-19 pandemic

    Article • BMC Infectious Diseases, July 2022, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  9. Acute phase of COVID-19 is associated with elevated plasmablasts in the blood

    Article • Bratislava Medical Journal, January 2022, AEPress, s.r.o.

    prof. dr.-med. Michal Holub

  10. Chronic Hepatitis C Virus Infection Modulates the Transcriptional Profiles of CD4+ T Cells

    Article • Canadian Journal of Infectious Diseases and Medical Microbiology, March 2021, Hindawi Publishing Corporation

    prof. dr.-med. Michal Holub

  11. Fatal Neutropenic Colitis and Clostridium Septicum Bacteremia in a Breast Cancer Patient

    Article • Prague Medical Report, January 2021, Charles University in Prague, Karolinum Press

    prof. dr.-med. Michal Holub

  12. Salmonella Paratyphi Infection: Use of Nanopore Sequencing as a Vivid Alternative for the Identification of Invading Bacteria

    Article • Prague Medical Report, January 2021, Charles University in Prague, Karolinum Press

    prof. dr.-med. Michal Holub

  13. Geographical and temporal distribution of SARS-CoV-2 clades in the WHO European Region, January to June 2020

    Article • Eurosurveillance, August 2020, European Centre for Disease Control and Prevention (ECDC)

    Dr Christoph Bock, prof. dr.-med. Michal Holub

  14. Frequent Recurrences of Genital Herpes Are Associated with Enhanced Systemic HSV-Specific T Cell Response

    Article • Canadian Journal of Infectious Diseases and Medical Microbiology, January 2020, Hindawi Publishing Corporation

    prof. dr.-med. Michal Holub

  15. Calprotectin and Calgranulin C as Biomarkers of Pancreatic Tumors: Baseline Levels and Level Changes after Surgery

    Article • Mediators of Inflammation, September 2019, Hindawi Publishing Corporation

    prof. dr.-med. Michal Holub

  16. Antithrombin III as prognostic marker of severity of acute hepatitis B

    Article • Indian Journal of Gastroenterology, April 2019, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  17. New biomarkers of bacterial sepsis and antibiotic therapy effectiveness

    Article • Diagnostic Microbiology and Infectious Disease, March 2019, Elsevier

    prof. dr.-med. Michal Holub

  18. Alarmins as biomarkers of gastrointestinal surgical injury - a pilot study

    Article • Apmis, January 2018, Wiley

    prof. dr.-med. Michal Holub

  19. Serum biomarkers associated with the site and etiology of sepsis

    Article • Mediators of Inflammation, January 2018, Hindawi Publishing Corporation

    prof. dr.-med. Michal Holub

  20. Case of Early Neurosyphilis with Neurocognitive Impairment

    Article • Česká a slovenská neurologie a neurochirurgie, November 2017, Ambit Media, a.s.

    prof. dr.-med. Michal Holub

  21. Calgranulin C and calprotectin as biomarkers of severe bacterial infection

    Article • Journal of Critical Care, August 2017, Elsevier

    prof. dr.-med. Michal Holub

  22. Past and Present ARDS Mortality Rates: A Systematic Review

    Article • Respiratory Care, November 2016, Daedalus Enterprises

    prof. dr.-med. Michal Holub

  23. Alarmins and Clinical Outcomes After Major Abdominal Surgery—A Prospective Study

    Article • Journal of Investigative Surgery, September 2016, Taylor & Francis

    prof. dr.-med. Michal Holub

  24. Lemierre's syndrome

    Article • International Journal of Infectious Diseases, August 2016, Elsevier

    prof. dr.-med. Michal Holub

  25. Effect of antiviral treatment of chronic hepatitis C on the frequency of regulatory T cells, T-cell activation, and serum levels of TGF-beta

    Article • Apmis, June 2016, Wiley

    prof. dr.-med. Michal Holub

  26. The Effect of LatentToxoplasma gondiiInfection on the Immune Response in HIV-Infected Patients

    Article • BioMed Research International, January 2015, Hindawi Publishing Corporation

    prof. dr.-med. Michal Holub

  27. Incidence, immunological and clinical characteristics of reactivation of latentToxoplasma gondiiinfection in HIV-infected patients

    Article • Epidemiology and Infection, May 2014, Cambridge University Press

    prof. dr.-med. Michal Holub

  28. Targeted mass spectrometry analysis of neutrophil-derived proteins released during sepsis progression

    Article • Thrombosis and Haemostasis, January 2014, Schattauer GmbH

    prof. dr.-med. Michal Holub

  29. Endemic Hepatitis E in the Czech Republic

    Article • Clinical Infectious Diseases, November 2013, Oxford University Press (OUP)

    prof. dr.-med. Michal Holub

  30. Toxic Shock Syndrome and Persistent Immune Activation in an HIVPositive Patient

    Article • Current HIV Research, September 2013, Bentham Science Publishers

    prof. dr.-med. Michal Holub

  31. Different cytokine production and toll-like receptor expression induced by heat-killed invasive and carrier strains ofNeisseria meningitidis

    Article • Apmis, March 2013, Wiley

    prof. dr.-med. Michal Holub

  32. Cytokines and Chemokines as Biomarkers of Community-Acquired Bacterial Infection

    Article • Mediators of Inflammation, January 2013, Hindawi Publishing Corporation

    prof. dr.-med. Michal Holub

  33. Should heparin-binding protein levels be routinely monitored in patients with severe sepsis and septic shock?

    Article • Critical Care, June 2012, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  34. Reply to Dr. Rashmi Ranjan Das on the question, “Should procalcitonin be used as a routine biomarker of bacterial infection?”

    Article • Infection, March 2012, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  35. Electron microscopy in the diagnosis of viral gastroenteritis in hospitalised children in the Czech Republic

    Article • Folia Microbiologica, March 2012, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  36. Neutrophil to lymphocyte count ratio as a biomarker of bacterial infections

    Article • Open Medicine, January 2012, De Gruyter

    prof. dr.-med. Michal Holub

  37. Cortisol kinetics in cerebrospinal fluid during bacterial meningitis

    Article • Journal of Clinical Neuroscience, July 2011, Elsevier

    prof. dr.-med. Michal Holub

  38. Evaluation of potential biomarkers for the discrimination of bacterial and viral infections

    Article • Infection, July 2011, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  39. Detection and Phylogenetic Characterization of Human Hepatitis E Virus Strains, Czech Republic

    Article • Emerging Infectious Diseases, May 2011, Centers for Disease Control and Prevention (CDC)

    prof. dr.-med. Michal Holub

  40. Antiretroviral Treatment of HIV Infection Does Not Influence HIVSpecific Immunity but Has an Impact on Non-Specific Immune Activation

    Article • Current HIV Research, March 2011, Bentham Science Publishers

    prof. dr.-med. Michal Holub

  41. Differences in Toll-like receptor expression and cytokine production after stimulation with heat-killed gram-positive and gram-negative bacteria

    Article • Folia Microbiologica, March 2011, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  42. Clinical Aspects of Sepsis

    Article • January 2011, Karger Publishers

    prof. dr.-med. Michal Holub

  43. Jaundice complicated by an atypical form of Guillain-Barré syndrome

    Article • Journal of Clinical Virology, December 2010, Elsevier

    prof. dr.-med. Michal Holub

  44. Heparin-binding protein as a biomarker of circulatory failure during severe infections: A report of three cases

    Article • Scandinavian Journal of Infectious Diseases, April 2010, Taylor & Francis

    prof. dr.-med. Michal Holub

  45. Acute Appendicitis as a Manifestation of the Immune Reconstitution Inflammatory Syndrome

    Article • Current HIV Research, September 2009, Bentham Science Publishers

    prof. dr.-med. Michal Holub

  46. Favorable Outcome of Severe Acute Hepatitis B in a Patient Treated with Antithrombin III and Antiviral Therapy

    Article • Clinical Infectious Diseases, August 2009, Oxford University Press (OUP)

    prof. dr.-med. Michal Holub

  47. Sequential analysis of biomarkers in cerebrospinal fluid and serum during invasive meningococcal disease

    Article • European Journal of Clinical Microbiology & Infectious Diseases, February 2009, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  48. Thromboembolic complications of sepsis: What is the incidence and pathophysiological mechanisms involved?

    Article • Thrombosis and Haemostasis, January 2008, Schattauer GmbH

    prof. dr.-med. Michal Holub

  49. Neisseria meningitidis strains from patients with invasive meningococcal disease differ in stimulation of cytokine production

    Article • Folia Microbiologica, September 2007, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  50. Cortisol levels in cerebrospinal fluid correlate with severity and bacterial origin of meningitis

    Article • Critical Care, January 2007, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  51. Effects of murine endotoxemia on lymphocyte subsets and clearance of staphylococcal pulmonary infection

    Article • Folia Microbiologica, September 2006, Springer Science + Business Media

    prof. dr.-med. Michal Holub

  52. Influence of endotoxin-induced acute lung injury on pulmonary innate and adaptive immunity

    Article • Apmis, May 2003, Wiley

    prof. dr.-med. Michal Holub

  53. Lymphocyte subset numbers depend on the bacterial origin of sepsis

    Article • Clinical Microbiology and Infection, March 2003, Elsevier

    prof. dr.-med. Michal Holub

  54. Lymphocyte subset numbers in cerebrospinal fluid: comparison of tick-borne encephalitis and neuroborreliosis

    Article • Acta Neurologica Scandinavica, November 2002, Wiley

    prof. dr.-med. Michal Holub

  55. Changes in lymphocyte subpopulations and CD3+/DR + expression in sepsis

    Article • Clinical Microbiology and Infection, December 2000, Elsevier

    prof. dr.-med. Michal Holub