All Stories

  1. Lung Cancer Cell-Derived Secretome Mediates Paraneoplastic Inflammation and Fibrosis in Kidney in Mice
  2. A selective drug delivery system based on phospholipid-type nanobubbles for lung cancer therapy
  3. Kinase shRNA screening reveals that TAOK3 enhances microtubule-targeted drug resistance of breast cancer cells via the NF-κB signaling pathway
  4. The Diverse Roles of TAO Kinases in Health and Diseases
  5. Omics-Based Platforms: Current Status and Potential Use for Cholangiocarcinoma
  6. Downregulation of STK4 promotes colon cancer invasion/migration through blocking β‐catenin degradation
  7. Ovatodiolide, isolated from Anisomeles indica, suppresses bladder carcinogenesis through suppression of mTOR/β-catenin/CDK6 and exosomal miR-21 derived from M2 tumor-associated macrophages
  8. An Annotation-free Whole-slide Training Approach to Pathological Classification of Lung Cancer Types by Deep Neural Network
  9. Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway
  10. Aberrantly expressed Bruton’s tyrosine kinase preferentially drives metastatic and stem cell-like phenotypes in neuroblastoma cells
  11. Selection of a malignant subpopulation from a colorectal cancer cell line
  12. EFHD2 contributes to non-small cell lung cancer cisplatin resistance by the activation of NOX4-ROS-ABCC1 axis
  13. Stabilization of ADAM9 by N-α-acetyltransferase 10 protein contributes to promoting progression of androgen-independent prostate cancer
  14. Circulating proteoglycan endocan mediates EGFR-driven progression of non-small cell lung cancer
  15. CX3CR1-microglia mediates neuroinflammation and blood pressure regulation in the nucleus tractus solitarii of fructose-induced hypertensive rats
  16. Melatonin­triggered post‐transcriptional and post‐translational modifications of ADAMTS1 coordinately retard tumorigenesis and metastasis of renal cell carcinoma
  17. IMPAD1 functions as mitochondrial electron transport inhibitor that prevents ROS production and promotes lung cancer metastasis through the AMPK-Notch1-HEY1 pathway
  18. Monoamine Oxidase B Expression Correlates with a Poor Prognosis in Colorectal Cancer Patients and Is Significantly Associated with Epithelial-to-Mesenchymal Transition-Related Gene Signatures
  19. Next‐Generation Cancer‐Specific Hybrid Theranostic Nanomaterials: MAGE‐A3 NIR Persistent Luminescence Nanoparticles Conjugated to Afatinib for In Situ Suppression of Lung Adenocarcinoma Growth and Metastasis
  20. Nonenzymatic function of Aldolase A downregulates miR-145 to promote the Oct4/DUSP4/TRAF4 axis and the acquisition of lung cancer stemness
  21. PRKDC: new biomarker and drug target for checkpoint blockade immunotherapy
  22. Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFNγ axis
  23. Magnetically Guided Theranostics: Optimizing Magnetic Resonance Imaging with Sandwich-Like Kaolinite-Based Iron/Platinum Nanoparticles for Magnetic Fluid Hyperthermia and Chemotherapy
  24. Theranostic nanobubble encapsulating a plasmon-enhanced upconversion hybrid nanosystem for cancer therapy
  25. Pin1 coordinates HDAC6 upregulation with cell migration in lung cancer cells
  26. Ovatodiolide Suppresses Oral Cancer Malignancy by Down-Regulating Exosomal Mir-21/STAT3/β-Catenin Cargo and Preventing Oncogenic Transformation of Normal Gingival Fibroblasts
  27. CD47-SIRPα Signaling Induces Epithelial-Mesenchymal Transition and Cancer Stemness and Links to a Poor Prognosis in Patients with Oral Squamous Cell Carcinoma
  28. FOXD1 and Gal-3 Form a Positive Regulatory Loop to Regulate Lung Cancer Aggressiveness
  29. Follistatin-like protein 1 inhibits lung cancer metastasis by preventing proteolytic activation of osteopontin
  30. Overexpression of BZW1 is an independent poor prognosis marker and its down-regulation suppresses lung adenocarcinoma metastasis
  31. A Novel Multi-Target Small Molecule, LCC-09, Inhibits Stemness and Therapy-Resistant Phenotypes of Glioblastoma Cells by Increasing miR-34a and Deregulating the DRD4/Akt/mTOR Signaling Axis
  32. A co-expressed gene status of adenylate kinase 1/4 reveals prognostic gene signature associated with prognosis and sensitivity to EGFR targeted therapy in lung adenocarcinoma
  33. Enrichment of Aldolase C Correlates with Low Non-Mutated IDH1 Expression and Predicts a Favorable Prognosis in Glioblastomas
  34. Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival
  35. ATP Synthase Subunit Epsilon Overexpression Promotes Metastasis by Modulating AMPK Signaling to Induce Epithelial-to-Mesenchymal Transition and Is a Poor Prognostic Marker in Colorectal Cancer Patients
  36. Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response
  37. Ambient particulate matter attenuates Sirtuin1 and augments SREBP1-PIR axis to induce human pulmonary fibroblast inflammation: molecular mechanism of microenvironment associated with COPD
  38. The Depletion of the “Don’t-Eat-Me” Signal CD47 Increases Radiosensitivity through Phenotypical Attenuation of Cancer Stem Cell and EMT Properties in Oral Squamous Cell Carcinoma Cells
  39. Development of upconversion nanoparticle-conjugated indium phosphide quantum dot for matrix metalloproteinase-2 cancer transformation sensing
  40. Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2
  41. AKR1C1 controls cisplatin-resistance in head and neck squamous cell carcinoma through cross-talk with the STAT1/3 signaling pathway
  42. Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis
  43. Comparison of cofilin‑1 and Twist‑1 protein expression in human non‑small cell lung cancer tissues
  44. Ghrelin Upregulates Oncogenic Aurora A to Promote Renal Cell Carcinoma Invasion
  45. Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer
  46. Inhibition of FAK Signaling Elicits Lamin A/C-Associated Nuclear Deformity and Cellular Senescence
  47. Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis
  48. Ovatodiolide Inhibits the Oncogenicity and Cancer Stem Cell-like Phenotype of Glioblastoma Cells, as well as Potentiate the Anticancer Effect of Temozolomide
  49. Graphitic carbon nitride-based nanocomposites and their biological applications: a review
  50. The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells
  51. High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma
  52. The Disruption of the β-Catenin/TCF-1/STAT3 Signaling Axis by 4-Acetylantroquinonol B Inhibits the Tumorigenesis and Cancer Stem-Cell-Like Properties of Glioblastoma Cells, In Vitro and In Vivo
  53. Kinome-Wide siRNA Screening Identifies Src-Enhanced Resistance of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells
  54. Over-expression of TNNI3K is associated with early-stage carcinogenesis of cholangiocarcinoma
  55. Antibody-drug conjugates with HER2-targeting antibodies from synthetic antibody libraries are highly potent against HER2-positive human gastric tumor in xenograft models
  56. N-α-acetyltransferase 10 protein promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas
  57. Destruxin B Suppresses Drug-Resistant Colon Tumorigenesis and Stemness Is Associated with the Upregulation of miR-214 and Downregulation of mTOR/β-Catenin Pathway
  58. Correction to: CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation
  59. Downregulating CD26/DPPIV by apigenin modulates the interplay between Akt and Snail/Slug signaling to restrain metastasis of lung cancer with multiple EGFR statuses
  60. 4-Acetyl-Antroquinonol B Suppresses SOD2-Enhanced Cancer Stem Cell-Like Phenotypes and Chemoresistance of Colorectal Cancer Cells by inducing hsa-miR-324 re-Expression
  61. Histone demethylase JARID1B/KDM5B promotes aggressiveness of non-small cell lung cancer and serves as a good prognostic predictor
  62. Roles of Aldolase Family Genes in Human Cancers and Diseases
  63. 4-Acetyl-antroquinonol B Suppresses SOD2-Enhanced Cancer Stem Cell-Like Phenotypes and Chemoresistance of Colorectal Cancer Cells by Inducing hsa-miR-324 Re-Expression
  64. Over-expression of lysyl oxidase is associated with poor prognosis and response to therapy of patients with lower grade gliomas
  65. A novel long non-coding RNA linc-ZNF469-3 promotes lung metastasis through miR-574-5p-ZEB1 axis in triple negative breast cancer
  66. Nuclear translocation of PKM2/AMPK complex sustains cancer stem cell populations under glucose restriction stress
  67. Leptin signaling axis specifically associates with clinical prognosis and is multifunctional in regulating cancer progression
  68. Near-Infrared-Activated Fluorescence Resonance Energy Transfer-Based Nanocomposite to Sense MMP2-Overexpressing Oral Cancer Cells
  69. Single 808 nm Laser Treatment Comprising Photothermal and Photodynamic Therapies by Using Gold Nanorods Hybrid Upconversion Particles
  70. Pyruvate kinase M2 promotes pancreatic ductal adenocarcinoma invasion and metastasis through phosphorylation and stabilization of PAK2 protein
  71. Leukocyte Cell-Derived Chemotaxin 2 Retards Non-Small Cell Lung Cancer Progression Through Antagonizing MET and EGFR Activities
  72. Downregulation of Cancer Stemness by Novel Diterpenoid Ovatodiolide Inhibits Hepatic Cancer Stem Cell-Like Traits by Repressing Wnt/β-Catenin Signaling
  73. Nanobubble-embedded inorganic 808 nm excited upconversion nanocomposites for tumor multiple imaging and treatment
  74. Pin1 Is Involved in HDAC6-mediated Cancer Cell Motility
  75. Identification of MALT1 as both a prognostic factor and a potential therapeutic target of regorafenib in cholangiocarcinoma patients
  76. miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer
  77. CHAC2 is essential for self-renewal and glutathione maintenance in human embryonic stem cells
  78. BICD1 expression, as a potential biomarker for prognosis and predicting response to therapy in patients with glioblastomas
  79. Hepatocellular carcinoma-targeted nanoparticles for cancer therapy
  80. Fructose induced neurogenic hypertension mediated by overactivation of p38 MAPK to impair insulin signaling transduction caused central insulin resistance
  81. Fibroblast activation protein augments progression and metastasis of pancreatic ductal adenocarcinoma
  82. KSRP suppresses cell invasion and metastasis through miR-23a-mediated EGR3 mRNA degradation in non-small cell lung cancer
  83. Quercetin suppresses the metastatic ability of lung cancer through inhibiting Snail-dependent Akt activation and Snail-independent ADAM9 expression pathways
  84. Adenylate kinase-4 modulates oxidative stress and stabilizes HIF-1α to drive lung cancer metastasis
  85. Feedback regulation of ALDOA activates the HIF-1α/MMP9 axis to promote lung cancer progression
  86. Decrease of FSTL1-BMP4-Smad signaling predicts poor prognosis in lung adenocarcinoma but not in squamous cell carcinoma
  87. Global Proteomics-based Identification and Validation of Thymosin Beta-4 X-Linked as a Prognostic Marker for Head and Neck Squamous Cell Carcinoma
  88. CLEC5A is essential for host defense against bacterial infection.
  89. Protease-activated nanomaterials for targeted cancer theranostics
  90. Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis
  91. Ghrelin and cancer progression
  92. Elimination of undifferentiated human embryonic stem cells by cardiac glycosides
  93. Antrodia cinnamomea sensitizes radio-/chemo-therapy of cancer stem-like cells by modulating microRNA expression
  94. Investigation of nanoparticle-assisted ultrasound therapy for treating implanted breast tumors in mice
  95. 3′UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma
  96. Differential synchrotron X-ray imaging markers based on the renal microvasculature for tubulointerstitial lesions and glomerulopathy
  97. 4-Acetylantroquinonol B suppresses autophagic flux and improves cisplatin sensitivity in highly aggressive epithelial cancer through the PI3K/Akt/mTOR/p70S6K signaling pathway
  98. Minimizing the Heat Effect of Photodynamic Therapy Based on Inorganic Nanocomposites Mediated by 808 nm Near-Infrared Light
  99. CTMP, a predictive biomarker for trastuzumab resistance in HER2-enriched breast cancer patient
  100. Corrigendum to “Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells” [383 (2016) 282–294]
  101. Erratum: Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association
  102. A Fas ligand (FasL)-fused humanized antibody against tumor-associated glycoprotein 72 selectively exhibits the cytotoxic effect against oral cancer cells with a low FasL/Fas ratio
  103. Histone methyltransferase G9a drives chemotherapy resistance by regulating the glutamate-cysteine ligase catalytic subunit in head and neck squamous cell carcinoma
  104. MART-10 represses cholangiocarcinoma cell growth and high vitamin D receptor expression indicates better prognosis for cholangiocarcinoma
  105. Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts
  106. Ovatodiolide suppresses colon tumorigenesis and prevents polarization of M2 tumor-associated macrophages through YAP oncogenic pathways
  107. Erratum: Corrigendum: Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress
  108. The STAT3-miRNA-92-Wnt Signaling Pathway Regulates Spheroid Formation and Malignant Progression in Ovarian Cancer
  109. Erratum to: E1A-Mediated Inhibition of HSPA5 Suppresses Cell Migration and Invasion in Triple-Negative Breast Cancer
  110. Elevation of β-galactoside α2,6-sialyltransferase 1 in a fructoseresponsive manner promotes pancreatic cancer metastasis
  111. Parathyroid Hormone-Like Hormone is a Poor Prognosis Marker of Head and Neck Cancer and Promotes Cell Growth via RUNX2 Regulation
  112. Glucose transporter 4 promotes head and neck squamous cell carcinoma metastasis through the TRIM24-DDX58 axis
  113. Lysosomal acid phosphatase 2 is an unfavorable prognostic factor but is associated with better survival in stage II colorectal cancer patients receiving chemotherapy
  114. Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility
  115. Renal Denervation Improves the Baroreflex and GABA System in Chronic Kidney Disease-induced Hypertension
  116. Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells
  117. Plasmon-Enhanced Photodynamic Cancer Therapy by Upconversion Nanoparticles Conjugated with Au Nanorods
  118. Dengue Virus Infection Is through a Cooperative Interaction between a Mannose Receptor and CLEC5A on Macrophage as a Multivalent Hetero-Complex
  119. Dysregulation of RUNX2/Activin-A Axis upon miR-376c Downregulation Promotes Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma
  120. Near-Infrared Light-Mediated Photodynamic Therapy Nanoplatform by the Electrostatic Assembly of Upconversion Nanoparticles with Graphitic Carbon Nitride Quantum Dots
  121. Paricalcitol Attenuates Cardiac Fibrosis and Expression of Endothelial Cell Transition Markers in Isoproterenol-Induced Cardiomyopathic Rats
  122. Granulysin expressed in a humanized mouse model induces apoptotic cell death and suppresses tumorigenicity
  123. Sirtuin 6 suppresses hypoxia-induced inflammatory response in human osteoblasts via inhibition of reactive oxygen species production and glycolysis-A therapeutic implication in inflammatory bone resorption
  124. The opposite prognostic effect of NDUFS1 and NDUFS8 in lung cancer reflects the oncojanus role of mitochondrial complex I
  125. Inhibition of VEGF165/VEGFR2-dependent signaling by LECT2 suppresses hepatocellular carcinoma angiogenesis
  126. MiR-193a-5p/ERBB2 act as concurrent chemoradiation therapy response indicator of esophageal squamous cell carcinoma
  127. Selective killing of cancer cells by nanoparticle-assisted ultrasound
  128. MMP2-sensing up-conversion nanoparticle for fluorescence biosensing in head and neck cancer cells
  129. Folate deficient tumor microenvironment promotes epithelial-to-mesenchymal transition and cancer stem-like phenotypes
  130. Glycolipid GD3 and GD3 synthase are key drivers for glioblastoma stem cells and tumorigenicity
  131. Resveratrol Inhibition of Rac1-Derived Reactive Oxygen Species by AMPK Decreases Blood Pressure in a Fructose-Induced Rat Model of Hypertension
  132. Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis
  133. Huntingtin-Interacting Protein-1 Is an Early-Stage Prognostic Biomarker of Lung Adenocarcinoma and Suppresses Metastasis via Akt-mediated Epithelial–Mesenchymal Transition
  134. IL-8 induces miR-424-5p expression and modulates SOCS2/STAT5 signaling pathway in oral squamous cell carcinoma
  135. The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation
  136. Aberrant KDM5B expression promotes aggressive breast cancer through MALAT1 overexpression and downregulation of hsa-miR-448
  137. Melatonin inhibits MMP-9 transactivation and renal cell carcinoma metastasis by suppressing Akt-MAPKs pathway and NF-κB DNA-binding activity
  138. Periostin in tumor microenvironment is associated with poor prognosis and platinum resistance in epithelial ovarian carcinoma
  139. Evaluation of the intracellular uptake and cytotoxicity effect of TiO2 nanostructures for various human oral and lung cells under dark conditions
  140. Stage-specific embryonic antigen-3 (SSEA-3) and β3GalT5 are cancer specific and significant markers for breast cancer stem cells
  141. Suppression of fructose-bisphosphate aldolase C expression as a predictor of advanced oral squamous cell carcinoma
  142. GIT1 promotes lung cancer cell metastasis through modulating Rac1/Cdc42 activity and is associated with poor prognosis
  143. Silencing JARID1B suppresses oncogenicity, stemness and increases radiation sensitivity in human oral carcinoma
  144. Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90–EGFR association
  145. Glycoprotein B7-H3 overexpression and aberrant glycosylation in oral cancer and immune response
  146. 4-Acetylantroquinonol B inhibits colorectal cancer tumorigenesis and suppresses cancer stem-like phenotype
  147. Heme oxygenase-1 ameliorates kidney ischemia-reperfusion injury in mice through extracellular signal-regulated kinase 1/2-enhanced tubular epithelium proliferation
  148. By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer
  149. DDX3 as a strongest prognosis marker and its downregulation promotes metastasis in colorectal cancer
  150. Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer
  151. Suppressive function of low-dose deguelin on the invasion of oral cancer cells by downregulating tumor necrosis factor alpha-induced nuclear factor-kappa B signaling
  152. CARMA3 Represses Metastasis Suppressor NME2 to Promote Lung Cancer Stemness and Metastasis
  153. Diverse Targets of  -Catenin during the Epithelial-Mesenchymal Transition Define Cancer Stem Cells and Predict Disease Relapse
  154. Keap1-Nrf2 Interaction Suppresses Cell Motility in Lung Adenocarcinomas by Targeting the S100P Protein
  155. Ghrelin promotes renal cell carcinoma metastasis via Snail activation and is associated with poor prognosis
  156. Nonautophagic cytoplasmic vacuolation death induction in human PC-3M prostate cancer by curcumin through reactive oxygen species -mediated endoplasmic reticulum stress
  157. Wnt Signaling Regulates Blood Pressure by Downregulating a GSK-3β–Mediated Pathway to Enhance Insulin Signaling in the Central Nervous System
  158. Akt suppresses DLK for maintaining self-renewal of mouse embryonic stem cells
  159. GPCR dimerization in brainstem nuclei contributes to the development of hypertension
  160. The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression
  161. Upregulation of miR-328 and inhibition of CREB-DNA-binding activity are critical for resveratrol-mediated suppression of matrix metalloproteinase-2 and subsequent metastatic ability in human osteosarcomas
  162. Evaluations of the Chemical Stability and Cytotoxicity of CuInS2and CuInS2/ZnS Core/Shell Quantum Dots
  163. The H3K9 Methyltransferase G9a Represses E-cadherin and is Associated with Myometrial Invasion in Endometrial Cancer
  164. Plasmon-induced hyperthermia: hybrid upconversion NaYF4:Yb/Er and gold nanomaterials for oral cancer photothermal therapy
  165. Preclinical investigation of ibrutinib, a Bruton’s kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes
  166. Downregulated miR329 and miR410 Promote the Proliferation and Invasion of Oral Squamous Cell Carcinoma by Targeting Wnt-7b
  167. Squalene Synthase Induces Tumor Necrosis Factor Receptor 1 Enrichment in Lipid Rafts to Promote Lung Cancer Metastasis
  168. E1A-Mediated Inhibition of HSPA5 Suppresses Cell Migration and Invasion in Triple-Negative Breast Cancer
  169. miR326 Maturation Is Crucial for VEGF-C-Driven Cortactin Expression and Esophageal Cancer Progression
  170. MTAP is an independent prognosis marker and the concordant loss of MTAP and p16 expression predicts short survival in non-small cell lung cancer patients
  171. MicroRNA-296-5p (miR-296-5p) functions as a tumor suppressor in prostate cancer by directly targeting Pin1
  172. Quercetin induces mitochondrial-derived apoptosis via reactive oxygen species-mediated ERK activation in HL-60 leukemia cells and xenograft
  173. Involvement of two distinct signalling pathways in IGF-1-mediated central control of hypotensive effects in normotensive and hypertensive rats
  174. Arsenic Trioxide Inhibits CXCR4-Mediated Metastasis by Interfering miR-520h/PP2A/NF-κB Signaling in Cervical Cancer
  175. Resveratrol decreases fructose‐induced oxidative stress, mediated by NADPH oxidase via an AMPK‐dependent mechanism
  176. Different Impacts of α- and β-Blockers in Neurogenic Hypertension Produced by Brainstem Lesions in Rat
  177. Autophagy promotes resistance to photodynamic therapy-induced apoptosis selectively in colorectal cancer stem-like cells
  178. MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo
  179. Stage-specific embryonic antigen-4 as a potential therapeutic target in glioblastoma multiforme and other cancers
  180. Vascular endothelial growth factor-C modulates proliferation and chemoresistance in acute myeloid leukemic cells through an endothelin-1-dependent induction of cyclooxygenase-2
  181. Leukocyte cell-derived chemotaxin 2 antagonizes MET receptor activation to suppress hepatocellular carcinoma vascular invasion by protein tyrosine phosphatase 1B recruitment
  182. Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma
  183. The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis
  184. Integrative transcriptome sequencing identifies trans-splicing events with important roles in human embryonic stem cell pluripotency
  185. Hispolon Induces Apoptosis through JNK1/2-Mediated Activation of a Caspase-8, -9, and -3-Dependent Pathway in Acute Myeloid Leukemia (AML) Cells and Inhibits AML Xenograft Tumor Growth in Vivo
  186. Baseline hypertension: New insight into the potential predictors of survival in patients with hepatocellular carcinoma
  187. Simvastatin induces a central hypotensive effect via Ras-mediated signalling to cause eNOS up-regulation
  188. Array-Based High-Throughput Screening in Mouse Embryonic Stem Cells with shRNAs
  189. Gfi-1 is the transcriptional repressor of SOCS1 in acute myeloid leukemia cells
  190. Targeting the XIAP/caspase-7 complex selectively kills caspase-3–deficient malignancies
  191. Pin1 acts as a negative regulator of the G2/M transition by interacting with the Aurora-A-Bora complex
  192. Carboxyl-Terminal Modulator Protein Positively Regulates Akt Phosphorylation and Acts as an Oncogenic Driver in Breast Cancer
  193. A sesquiterpene lactone antrocin from Antrodia camphorata negatively modulates JAK2/STAT3 signaling via microRNA let-7c and induces apoptosis in lung cancer cells
  194. Expression of GOLM1 Correlates with Prognosis in Human Hepatocellular Carcinoma
  195. Loss of RUNX3 increases osteopontin expression and promotes cell migration in gastric cancer
  196. Hexamethonium Reverses the Lethal Cardiopulmonary Damages in a Rat Model of Brainstem Lesions Mimicking Fatal Enterovirus 71 Encephalitis*
  197. Glycogen synthase kinase 3 β activity is required for hBora/Aurora A-mediated mitotic entry
  198. Simvastatin inhibits cysteine-rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin-1/FoxO3a signaling
  199. Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility
  200. Hypoxia-responsive miRNAs target argonaute 1 to promote angiogenesis
  201. Analysis of Protein-Protein Interactions in Cross-talk Pathways Reveals CRKL Protein as a Novel Prognostic Marker in Hepatocellular Carcinoma
  202. Chitosan-Modified Stable Colloidal Gold Nanostars for the Photothermolysis of Cancer Cells
  203. Endoplasmic reticulum ribosome-binding protein 1 (RRBP1) overexpression is frequently found in lung cancer patients and alleviates intracellular stress-induced apoptosis through the enhancement of GRP78
  204. Targeting polymeric fluorescent nanodiamond-gold/silver multi-functional nanoparticles as a light-transforming hyperthermia reagent for cancer cells
  205. A Preclinical Evaluation of Antimycin A as a Potential Antilung Cancer Stem Cell Agent
  206. BlueBerry Isolate, Pterostilbene, Functions as a Potential Anticancer Stem Cell Agent in Suppressing Irradiation-Mediated Enrichment of Hepatoma Stem Cells
  207. Inhibition of Metastatic Potential in Breast CarcinomaIn VivoandIn Vitrothrough Targeting VEGFRs and FGFRs
  208. Fucosyltransferase 8 as a functional regulator of nonsmall cell lung cancer
  209. Trifluoperazine, an Antipsychotic Agent, Inhibits Cancer Stem Cell Growth and Overcomes Drug Resistance of Lung Cancer
  210. CCN2 inhibits lung cancer metastasis through promoting DAPK-dependent anoikis and inducing EGFR degradation
  211. Cisplatin Selects for Multidrug-Resistant CD133+ Cells in Lung Adenocarcinoma by Activating Notch Signaling
  212. Exercise-induced SPARC prevents tumorigenesis of colon cancer
  213. Central hypotensive effects of neuropeptide Y are modulated by endothelial nitric oxide synthase after activation by ribosomal protein S6 kinase
  214. A shRNA Functional Screen Reveals Nme6 and Nme7 Are Crucial for Embryonic Stem Cell Renewal
  215. Adenylate Kinase-4 Is a Marker of Poor Clinical Outcomes That Promotes Metastasis of Lung Cancer by Downregulating the Transcription Factor ATF3
  216. MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
  217. Activation of Robo1 Signaling of Breast Cancer Cells by Slit2 from Stromal Fibroblast Restrains Tumorigenesis via Blocking PI3K/Akt/ -Catenin Pathway
  218. Renin activates PI3K-Akt-eNOS signalling through the angiotensin AT1 and Mas receptors to modulate central blood pressure control in the nucleus tractus solitarii
  219. ASK1 promotes apoptosis of normal and malignant plasma cells
  220. Expression of gremlin 1 correlates with increased angiogenesis and progression-free survival in patients with pancreatic neuroendocrine tumors
  221. Systemic human orbital fat-derived stem/stromal cell transplantation ameliorates acute inflammation in lipopolysaccharide-induced acute lung injury
  222. MiR-520h-mediated FOXC2 regulation is critical for inhibition of lung cancer progression by resveratrol
  223. Meiotic Competent Human Germ Cell-like Cells Derived from Human Embryonic Stem Cells Induced by BMP4/WNT3A Signaling and OCT4/EpCAM (Epithelial Cell Adhesion Molecule) Selection
  224. RUNX3-mediated transcriptional inhibition of Akt suppresses tumorigenesis of human gastric cancer cells
  225. Seedless, silver-induced synthesis of star-shaped gold/silver bimetallic nanoparticles as high efficiency photothermal therapy reagent
  226. WW domain-containing oxidoreductase promotes neuronal differentiation via negative regulation of glycogen synthase kinase 3β
  227. Recombinant viral protein promotes apoptosis and suppresses invasion of ovarian adenocarcinoma cells by targeting α5β1 integrin to down-regulate Akt and MMP-2
  228. Interaction between tumour necrosis factor-α gene polymorphisms and substance use on risk of betel quid-related oral and pharyngeal squamous cell carcinoma in Taiwan
  229. NAT2 slow acetylation haplotypes are associated with the increased risk of betel quid–related oral and pharyngeal squamous cell carcinoma
  230. TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer
  231. FOXO3a-Dependent Mechanism of E1A-Induced Chemosensitization
  232. Biocompatible transferrin-conjugated sodium hexametaphosphate-stabilized gold nanoparticles: synthesis, characterization, cytotoxicity and cellular uptake
  233. miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans
  234. The novel DNA alkylating agent BO-1090 suppresses the growth of human oral cavity cancer in xenografted and orthotopic mouse models
  235. Central nicotinic acetylcholine receptor involved in Ca2+-calmodulin-endothelial nitric oxide synthase pathway modulated hypotensive effects
  236. Epi process margin improvement using co-implantation to control Phosphorus diffusion in a DRAM manufacturing
  237. Synergism between p53 and Mcl-1 in protecting from hepatic injury, fibrosis and cancer
  238. X-ray synthesized PEGylated (polyethylene glycol coated) gold nanoparticles in mice strongly accumulate in tumors
  239. N-α-Acetyltransferase 10 Protein Suppresses Cancer Cell Metastasis by Binding PIX Proteins and Inhibiting Cdc42/Rac1 Activity
  240. Minocycline inhibits the growth of glioma by inducing autophagy
  241. Manganese superoxide dismutase and glutathione peroxidase as prognostic markers in patients with buccal mucosal squamous cell carcinomas
  242. Modulating cell-uptake behavior of Au-based nanomaterials via quantitative biomolecule modification
  243. IL-10 Promoter Genetic Polymorphisms and Risk of Kawasaki Disease in Taiwan
  244. IL-6 Trans-Signaling in Formation and Progression of Malignant Ascites in Ovarian Cancer
  245. H3K9 Histone Methyltransferase G9a Promotes Lung Cancer Invasion and Metastasis by Silencing the Cell Adhesion Molecule Ep-CAM
  246. Polyethylenimine-mediated PUMA gene delivery to orthotopic oral cancer: Suppression of tumor growth through apoptosis induction in situ and prolonged survival
  247. hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing
  248. CYR61 Regulates BMP-2-dependent Osteoblast Differentiation through the αvβ3Integrin/Integrin-linked Kinase/ERK Pathway
  249. Downregulation of MicroRNA miR-520h by E1A Contributes to Anticancer Activity
  250. Dermcidin identification from exhaled air for lung cancer diagnosis
  251. Angiotensin II Inhibits Neuronal Nitric Oxide Synthase Activation Through the ERK1/2-RSK Signaling Pathway to Modulate Central Control of Blood Pressure
  252. Simvastatin inhibits cytokine-stimulated Cyr61 expression in osteoblastic cells: A therapeutic benefit for arthritis
  253. Biocompatibility of Fe3O4nanoparticles evaluated byin vitrocytotoxicity assays using normal, glia and breast cancer cells
  254. Enhancement of cell radiation sensitivity by pegylated gold nanoparticles
  255. Diagnosis of Gastric Malignancy Using Gastric Juice  1-antitrypsin
  256. Cytokine Genetic Polymorphisms and Susceptibility to Kawasaki Disease in Taiwanese Children
  257. Gastric juice acidity in upper gastrointestinal diseases
  258. Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/ AP-1 pathway
  259. MicroRNA-373 (miR-373) post-transcriptionally regulates large tumor suppressor, homolog 2 (LATS2) and stimulates proliferation in human esophageal cancer
  260. Suberoylanilide hydroxamic acid sensitizes human oral cancer cells to TRAIL-induced apoptosis through increase DR5 expression
  261. MicroRNA-330 acts as tumor suppressor and induces apoptosis of prostate cancer cells through E2F1-mediated suppression of Akt phosphorylation
  262. Biosensing, Cytotoxicity, and Cellular Uptake Studies of Surface-Modified Gold Nanorods
  263. Loss of RUNX3 Expression Correlates with Differentiation, Nodal Metastasis, and Poor Prognosis of Gastric Cancer
  264. Pin1 overexpression is associated with poor differentiation and survival in oral squamous cell carcinoma
  265. Neuronal Nitric Oxide Synthase Activation Is Involved in Insulin-Mediated Cardiovascular Effects in the Nucleus Tractus Solitarii of Rats
  266. MicroRNA-122, a tumor suppressor microRNA that regulates intrahepatic metastasis of hepatocellular carcinoma
  267. Investigation of the Growth Mechanism of Iron Oxide Nanoparticles via a Seed-Mediated Method and Its Cytotoxicity Studies
  268. Essential roles of caspases and their upstream regulators in rotenone-induced apoptosis
  269. Identification of SOX4 target genes using phylogenetic footprinting-based prediction from expression microarrays suggests that overexpression of SOX4 potentiates metastasis in hepatocellular carcinoma
  270. Octadecaborane implant technology for 72nm node stack DRAM p+ poly gate doping process
  271. Adenosine Modulates Cardiovascular Functions Through Activation of Extracellular Signal-Regulated Kinases 1 and 2 and Endothelial Nitric Oxide Synthase in the Nucleus Tractus Solitarii of Rats
  272. Correction
  273. Defective Phosphatidylinositol 3-Kinase Signaling in Central Control of Cardiovascular Effects in the Nucleus Tractus Solitarii of Spontaneously Hypertensive Rats
  274. Observation of peptide differences between cancer and control in gastric juice
  275. The significance of ANXA7 expression and its correlation with poor cellular differentiation and enhanced metastatic potential of gastric cancer
  276. Glycine N-methyltransferase−/− mice develop chronic hepatitis and glycogen storage disease in the liver
  277. Effect of theVP3gene of chicken anemia virus on canine mammary tumor cells
  278. Exogenous nitric oxide stimulated collagen type I expression and TGF-β1 production in keloid fibroblasts by a cGMP-dependent manner
  279. Nitric oxide promotes the progression of periapical lesion via inducing macrophage and osteoblast apoptosis
  280.  1-Antitrypsin Precursor in Gastric Juice Is a Novel Biomarker for Gastric Cancer and Ulcer
  281. Nitric oxide produced by iNOS is associated with collagen synthesis in keloid scar formation
  282. Induction of Heme Oxygenase-1 Is Involved in Carbon Monoxide-Mediated Central Cardiovascular Regulation
  283. The Interleukin-1 RN Polymorphism and Helicobacter pylori Infection in the Development of Duodenal Ulcer
  284. In Situ Akt Phosphorylation in the Nucleus Tractus Solitarii Is Involved in Central Control of Blood Pressure and Heart Rate
  285. COX-2 Regulates the Insulin-Like Growth Factor I-Induced Potentiation of Zn2+-Toxicity in Primary Cortical Culture
  286. The cardiovascular effects of nitric oxide and carbon monoxide in the nucleus tractus solitarii of rats
  287. Gene delivery of endothelial nitric oxide synthase into nucleus tractus solitarii induces biphasic response in cardiovascular functions of hypertensive rats
  288. Interactions of Carbon Monoxide and Metabotropic Glutamate Receptor Groups in the Nucleus Tractus Solitarii of Rats
  289. Loss of E-cadherin expression correlates with poor differentiation and invasion into adjacent organs in gastric adenocarcinomas
  290. Interaction of Carbon Monoxide and Adenosine in the Nucleus Tractus Solitarii of Rats
  291. Enhanced gene delivery to HER-2-overexpressing breast cancer cells by modified immunolipoplexes conjugated with the anti-HER-2 antibody
  292. Comparisons of norcantharidin cytotoxic effects on oral cancer cells and normal buccal keratinocytes
  293. Enhanced Gene Delivery to HER-2-Overexpressing Breast Cancer Cells by Modified Immunolipoplexes Conjugated with the Anti-HER-2 Antibody
  294. Nitric Oxide Promotes Infectious Bone Resorption by Enhancing Cytokine-Stimulated Interstitial Collagenase Synthesis in Osteoblasts
  295. Parietal Contusion and Transient Superior Sagittal Sinus Occlusion Presenting with Cortical Blindness
  296. Inducible Cyclooxygenase and Interleukin 6 Gene Expressions in Nasal Polyp Fibroblasts
  297. Sequential expressions of MMP-1, TIMP-1, IL-6, and COX-2 genes in induced periapical lesions in rats
  298. Mutation in the FGFR2 gene in a Taiwanese patient with Beare-Stevenson cutis gyrata syndrome
  299. Clinical characteristics of double pylorus
  300. Comparisons of Tumor Suppressor p53, p21, and p16 Gene Therapy Effects on Glioblastoma Tumorigenicity in Situ
  301. Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac
  302. Norcantharidin-Induced Post-G2/M Apoptosis Is Dependent on Wild-Type p53 Gene
  303. Expression of p16INK4A Induces Dominant Suppression of Glioblastoma Growth in Situ through Necrosis and Cell Cycle Arrest
  304. Genetic organization of alpha-bungarotoxins from Bungarus multicinctus (Taiwan banded krait): evidence showing that the production of alpha- bungarotoxin isotoxins is not derived from edited mRNAs
  305. Functional Expression of Human p21WAF1/CIP1Gene in Rat Glioma Cells Suppresses Tumor Growthin Vivoand Induces Radiosensitivity
  306. Intracavitary Liposome-Mediated p53 Gene Transfer into Glioblastoma with Endogenous Wild-Type p53in VivoResults in Tumor Suppression and Long-Term Survival
  307. Dissemination and tissue invasiveness in murine acute leukemia associated with acquisition ofp53 mutation and loss of wild-typep53
  308. Characterization of Functional Nanomaterials in Cosmetics and its Cytotoxic Effects
  309. The Synthesis of Iron Oxide Nanoparticles via Seed-Mediated Process and its Cytotoxicity Studies