All Stories

  1. Severe enterovirus A71 pathogenesis and immune responses in human nucleolin transgenic mice

    Article • Medical Microbiology and Immunology, June 2025, Springer Science + Business Media

    Professor Chuan Fa Chang

  2. Plasminogen deficiency reduces disease severity and immune responses in enterovirus A71-infected mice

    Article • Microbiology Spectrum, May 2025, ASM Journals

    Professor Chuan Fa Chang

  3. The Aloe vera acemannan polysaccharides inhibit phthalate-induced cell viability, metastasis, and stemness in colorectal cancer cells

    Article • Ecotoxicology and Environmental Safety, December 2024, Elsevier

    Professor Chuan Fa Chang

  4. Comprehensive analysis of bulk and single-cell RNA sequencing data reveals Schlafen-5 (SLFN5) as a novel prognosis and immunity

    Article • International Journal of Medical Sciences, January 2024, Ivyspring International Publisher

    Professor Chuan Fa Chang

  5. Long-term DEHP/MEHP exposure promotes colorectal cancer stemness associated with glycosylation alterations

    Article • Environmental Pollution, June 2023, Elsevier

    Professor Chuan Fa Chang

  6. Bioinformatics Analyses Identify the Therapeutic Potential of ST8SIA6 for Colon Cancer

    Article • Journal of Personalized Medicine, March 2022, MDPI AG

    Professor Chuan Fa Chang

  7. Carbohydrate Ligands for COVID-19 Spike Proteins

    Article • Viruses, February 2022, MDPI AG

    Professor Chuan Fa Chang

  8. An Increased Plasma Level of ApoCIII-Rich Electronegative High-Density Lipoprotein May Contribute to Cognitive Impairment in Alzheimer’s Disease

    Article • Biomedicines, November 2020, MDPI AG

    Professor Chuan Fa Chang

  9. Enterovirus A71 Containing Codon-Deoptimized VP1 and High-Fidelity Polymerase as Next-Generation Vaccine Candidate

    Article • Journal of Virology, July 2019, ASM Journals

    Professor Chuan Fa Chang

  10. Targeted Delivery of Curcumin Rescues Endoplasmic Reticulum–Retained Mutant NOX2 Protein and Avoids Leukocyte Apoptosis

    Article • The Journal of Immunology, June 2019, Oxford University Press (OUP)

    Professor Chuan Fa Chang

  11. Glycoproteomic identification of novel plasma biomarkers for oral cancer

    Article • Journal of Food and Drug Analysis, April 2019, The Journal of Food and Drug Analysis (JFDA), Food and Drug Administration, Taiwan (TFDA)

    Professor Chuan Fa Chang

  12. Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer

    Article • Proceedings of the National Academy of Sciences, February 2019, Proceedings of the National Academy of Sciences

    Professor Michael Hsiao, Professor Chuan Fa Chang

  13. Detection of adulterated drugs in traditional Chinese medicine and dietary supplements using hydrogen as a carrier gas

    Article • PLOS One, October 2018, PLOS

    Professor Chuan Fa Chang

  14. Glycan-binding preferences and genetic evolution of human seasonal influenza A(H3N2) viruses during 1999-2007 in Taiwan

    Article • PLOS One, May 2018, PLOS

    Professor Chuan Fa Chang

  15. Phthalate exposure promotes chemotherapeutic drug resistance in colon cancer cells

    Article • Oncotarget, December 2017, Impact Journals, LLC

    Professor Chuan Fa Chang

  16. Serum N-glycome characterization and anti-carbohydrate antibody profiling in oral squamous cell carcinoma patients

    Article • PLOS One, June 2017, PLOS

    Professor Chuan Fa Chang

  17. Monocytic thrombomodulin promotes cell adhesion through interacting with its ligand, Lewisy

    Article • Immunology and Cell Biology, November 2016, Wiley

    Professor Chuan Fa Chang

  18. Derivation of Cinnamon Blocks Leukocyte Attachment by Interacting with Sialosides

    Article • PLOS One, June 2015, PLOS

    Professor Chuan Fa Chang

  19. Lewisy Promotes Migration of Oral Cancer Cells by Glycosylation of Epidermal Growth Factor Receptor

    Article • PLOS One, March 2015, PLOS

    Professor Chuan Fa Chang

  20. Cell Surface Nucleolin Facilitates Enterovirus 71 Binding and Infection

    Article • Journal of Virology, February 2015, ASM Journals

    Professor Chuan Fa Chang

  21. Galectin-3 Silencing Inhibits Epirubicin-Induced ATP Binding Cassette Transporters and Activates the Mitochondrial Apoptosis Pathway via β-Catenin/GSK-3β Modulation in Colorectal Carcinoma

    Article • PLOS One, November 2013, PLOS

    Professor Chuan Fa Chang

  22. Anterior gradient 2: A novel sensitive tumor marker for metastatic oral cancer

    Article • Cancer Letters, October 2013, Elsevier

    Professor Chuan Fa Chang

  23. Recombinant Lectin-Like Domain of Thrombomodulin Suppresses Vascular Inflammation by Reducing Leukocyte Recruitment via Interacting With Lewis Y on Endothelial Cells

    Article • Arteriosclerosis Thrombosis and Vascular Biology, October 2013, Wolters Kluwer Health

    Professor Chuan Fa Chang

  24. Thrombomodulin functions as a plasminogen receptor to modulate angiogenesis

    Article • The FASEB Journal, August 2013, Wiley

    Professor Chuan Fa Chang

  25. Identification of novel tumor markers for oral squamous cell carcinoma using glycoproteomic analysis

    Article • Clinica Chimica Acta, May 2013, Elsevier

    Professor Chuan Fa Chang

  26. Cell surface sialylation affects binding of enterovirus 71 to rhabdomyosarcoma and neuroblastoma cells

    Article • BMC Microbiology, August 2012, Springer Science + Business Media

    Professor Chuan Fa Chang

  27. Receptor Binding Surveillance of Influenza Clinical Isolates

    Article • Future Virology, June 2012, Taylor & Francis

    Professor Chuan Fa Chang

  28. Characterization of glycan binding specificities of influenza B viruses with correlation with hemagglutinin genotypes and clinical features

    Article • Journal of Medical Virology, February 2012, Wiley

    Professor Chuan Fa Chang

  29. The recombinant lectin-like domain of thrombomodulin inhibits angiogenesis through interaction with Lewis Y antigen

    Article • Blood, February 2012, American Society of Hematology

    Professor Chuan Fa Chang

  30. Increased galectin-3 facilitates leukemia cell survival from apoptotic stimuli

    Article • Biochemical and Biophysical Research Communications, August 2011, Elsevier

    Professor Chuan Fa Chang

  31. Profiling of Influenza Viruses by High-Throughput Carbohydrate Membrane Array

    Article • Future Medicinal Chemistry, March 2011, Taylor & Francis

    Professor Chuan Fa Chang

  32. Rapid characterization of sugar-binding specificity by in-solution proximity binding with photosensitizers

    Article • Glycobiology, February 2011, Oxford University Press (OUP)

    Professor Chuan Fa Chang

  33. Functional characterisation of a complex mutation in the α(1,4)galactosyltransferase gene in Taiwanese individuals with p phenotype

    Article • Transfusion Medicine, November 2010, Wiley

    Professor Chuan Fa Chang

  34. ChemInform Abstract: Expeditious Synthesis of C-Glycosyl Conjugated Dienes and Aldehydes from Sugar Lactones.

    Article • ChemInform, May 2010, Wiley

    Professor Chuan Fa Chang

  35. Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response

    Article • Blood, November 2008, American Society of Hematology

    Professor Chuan Fa Chang

  36. C-Terminal Repeats of Clostridium difficile Toxin A Induce Production of Chemokine and Adhesion Molecules in Endothelial Cells and Promote Migration of Leukocytes

    Article • Infection and Immunity, December 2007, ASM Journals

    Professor Chuan Fa Chang

  37. Discovery of Different Types of Inhibition between the Human and Thermotoga maritima α-Fucosidases by Fuconojirimycin-Based Derivatives

    Article • Biochemistry, April 2006, American Chemical Society (ACS)

    Professor Chuan Fa Chang

  38. Discovery of Picomolar Slow Tight-Binding Inhibitors of α-Fucosidase

    Article • Chemistry & Biology, November 2004, Elsevier

    Professor Chuan Fa Chang

  39. Discovery of Picomolar Slow Tight-Binding Inhibitors of α-Fucosidase

    Article • Chemistry & Biology, September 2004, Elsevier

    Professor Chuan Fa Chang

  40. Rapid Diversity‐Oriented Synthesis in Microtiter Plates for in situ Screening: Discovery of Potent and Selective α‐Fucosidase Inhibitors.

    Article • ChemInform, November 2003, Wiley

    Professor Chuan Fa Chang

  41. Rapid Diversity‐Oriented Synthesis in Microtiter Plates for In Situ Screening: Discovery of Potent and Selective α‐Fucosidase Inhibitors

    Article • Angewandte Chemie, October 2003, Wiley

    Professor Chuan Fa Chang

  42. ChemInform Abstract: Inter‐ and Intramolecular Alcohol Additions to exo‐Glycals.

    Article • ChemInform, December 2002, Wiley

    Professor Chuan Fa Chang

  43. Inter- and intramolecular alcohol additions to exo -glycals

    Article • Tetrahedron Letters, September 2002, Elsevier

    Professor Chuan Fa Chang

  44. Expeditious synthesis of C-glycosyl conjugated dienes and aldehydes from sugar lactones

    Article • Tetrahedron Letters, July 2001, Elsevier

    Professor Chuan Fa Chang