Contact

All Stories

  1. Opt1 imports CoA precursors as glutathione mixed disulfides

    Article • Journal of Biological Chemistry, September 2025, Elsevier

    Michael Chang

  2. Cellular mechanisms that affect the stability of telomeric DNA repeats

    Article • Proceedings of the National Academy of Sciences, November 2024, Proceedings of the National Academy of Sciences

    Michael Chang

  3. Spindle assembly checkpoint does not promote the formation of gross chromosomal rearrangements

    Article • Genetics, September 2024, Oxford University Press (OUP)

    Michael Chang

  4. Interstitial telomeric sequences promote gross chromosomal rearrangement via multiple mechanisms

    Article • April 2024, Cold Spring Harbor Laboratory Press

    Michael Chang

  5. Revisiting the role of the spindle assembly checkpoint in the formation of gross chromosomal rearrangements inSaccharomyces cerevisiae

    Article • April 2024, Cold Spring Harbor Laboratory Press

    Michael Chang

  6. Deletion of MEC1 suppresses the replicative senescence of the cdc13-2 mutant in Saccharomyces cerevisiae

    Article • G3 Genes Genomes Genetics, March 2023, Oxford University Press (OUP)

    Michael Chang

  7. Deletion ofMEC1suppresses replicative senescence of thecdc13-2mutant inSaccharomyces cerevisiae

    Article • February 2023, Cold Spring Harbor Laboratory Press

    Michael Chang

  8. Detecting the metabolism of individual yeast mutant strain cells when aged, stressed or treated with antioxidants with diamond magnetometry

    Article • Nano Today, February 2023, Elsevier

    Michael Chang

  9. Investigating the role of G-quadruplexes at Saccharomyces cerevisiae telomeres

    Article • Microbial Cell, June 2022, Shared Science Publishers OG

    Michael Chang

  10. High-throughput replica-pinning approach to screen for yeast genes controlling low-frequency events

    Article • STAR Protocols, March 2022, Elsevier

    Michael Chang

  11. Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation in Saccharomyces cerevisiae

    Article • eLife, January 2022, eLife

    Michael Chang

  12. Suppression of cdc13-2-associated senescence by pif1-m2 requires Ku-mediated telomerase recruitment

    Article • G3 Genes Genomes Genetics, October 2021, Oxford University Press (OUP)

    Michael Chang

  13. A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers

    Article • G3 Genes Genomes Genetics, September 2021, Oxford University Press (OUP)

    Michael Chang

  14. A synthetic lethal screen identifies HDAC4 as a potential target in MELK overexpressing cancers

    Article • July 2021, Cold Spring Harbor Laboratory Press

    Michael Chang

  15. Suppression ofcdc13-2-associated senescence bypif1-m2requires Ku-mediated telomerase recruitment

    Article • March 2021, Cold Spring Harbor Laboratory Press

    Michael Chang

  16. Rif2 protects Rap1-depleted telomeres from MRX-mediated degradation inSaccharomyces cerevisiae

    Article • December 2020, Cold Spring Harbor Laboratory Press

    Michael Chang

  17. A Genome-Wide Screen for Genes Affecting Spontaneous Direct-Repeat Recombination inSaccharomyces cerevisiae

    Article • G3 Genes Genomes Genetics, June 2020, Oxford University Press (OUP)

    Michael Chang

  18. A genome-wide screen for genes affecting spontaneous direct-repeat recombination inSaccharomyces cerevisiae

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Michael Chang

  19. A genome‐wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells

    Article • Aging Cell, December 2019, Wiley

    Michael Chang

  20. A genome-wide screen identifies genes that suppress the accumulation of spontaneous mutations in young and aged yeast cells

    Article • December 2018, Cold Spring Harbor Laboratory Press

    Michael Chang

  21. Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in Saccharomyces cerevisiae

    Article • G3 Genes Genomes Genetics, August 2018, Oxford University Press (OUP)

    Michael Chang

  22. Guidelines and recommendations on yeast cell death nomenclature

    Article • Microbial Cell, January 2018, Shared Science Publishers OG

    Paula Ludovico, Maria João Sousa, Michael Chang

  23. Genome-wide mapping of sister chromatid exchange events in single yeast cells using Strand-seq

    Article • eLife, December 2017, eLife

    Michael Chang

  24. Telomerase regulation by the Pif1 helicase: a length-dependent effect?

    Article • Current Genetics, October 2017, Springer Science + Business Media

    Michael Chang

  25. A sharp Pif1-dependent threshold separates DNA double-strand breaks from critically short telomeres

    Article • eLife, August 2017, eLife

    Michael Chang

  26. Generally Applicable Transformation Protocols for Fluorescent Nanodiamond Internalization into Cells

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Michael Chang

  27. Double-strand breaks are not the main cause of spontaneous sister chromatid exchange in wild-type yeast cells

    Article • July 2017, Cold Spring Harbor Laboratory Press

    Michael Chang

  28. Increased genome instability is not accompanied by sensitivity to DNA damaging agents in aged yeast cells

    Article • DNA Repair, June 2017, Elsevier

    Michael Chang

  29. A simple microfluidic platform to study age-dependent protein abundance and localization changes in Saccharomyces cerevisiae

    Article • Microbial Cell, May 2017, Shared Science Publishers OG

    Michael Chang

  30. Multiple Rad52-Mediated Homology-Directed Repair Mechanisms Are Required to Prevent Telomere Attrition-Induced Senescence in Saccharomyces cerevisiae

    Article • PLoS Genetics, July 2016, PLOS

    Michael Chang

  31. Recombination-Mediated Telomere Maintenance in Saccharomyces cerevisiae Is Not Dependent on the Shu Complex

    Article • PLOS One, March 2016, PLOS

    Michael Chang

  32. The many facets of homologous recombination at telomeres

    Article • Microbial Cell, September 2015, Shared Science Publishers OG

    Michael Chang

  33. Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools

    Article • Genetics, April 2013, Oxford University Press (OUP)

    Michael Chang

  34. Rif2 Promotes a Telomere Fold-Back Structure through Rpd3L Recruitment in Budding Yeast

    Article • PLoS Genetics, September 2012, PLOS

    Michael Chang

  35. Long telomeres: too much of a good thing

    Article • BioMolecular Concepts, August 2012, De Gruyter

    Michael Chang

  36. Rif1/2 and Tel1 function in separate pathways during replicative senescence

    Article • Cell Cycle, November 2011, Taylor & Francis

    Michael Chang

  37. Long telomeres are preferentially extended during recombination-mediated telomere maintenance

    Article • Nature Structural & Molecular Biology, March 2011, Springer Science + Business Media

    Michael Chang

  38. Telomerase Is Essential to Alleviate Pif1-Induced Replication Stress at Telomeres

    Article • Genetics, November 2009, Oxford University Press (OUP)

    Michael Chang

  39. Tel2 Finally Tells One Story

    Article • Science, April 2008, American Association for the Advancement of Science

    Michael Chang

  40. Telomerase repeat addition processivity is increased at critically short telomeres in a Tel1-dependent manner in Saccharomyces cerevisiae

    Article • Genes & Development, October 2007, Cold Spring Harbor Laboratory Press

    Michael Chang

  41. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

    Article • Proceedings of the National Academy of Sciences, March 2006, Proceedings of the National Academy of Sciences

    Michael Chang

  42. Genomic Approaches for Identifying DNA Damage Response Pathways in S. cerevisiae

    Article • January 2006, Elsevier

    Michael Chang

  43. RMI1/NCE4, a suppressor of genome instability, encodes a member of the RecQ helicase/Topo III complex

    Article • The EMBO Journal, May 2005, Springer Science + Business Media

    Michael Chang

  44. The Origin Recognition Complex Links Replication, Sister Chromatid Cohesion and Transcriptional Silencing in Saccharomyces cerevisiae

    Article • Genetics, June 2004, Oxford University Press (OUP)

    Michael Chang

  45. Identification of Protein Complexes Required for Efficient Sister Chromatid Cohesion

    Article • Molecular Biology of the Cell, April 2004, American Society for Cell Biology (ASCB)

    Michael Chang

  46. Global Mapping of the Yeast Genetic Interaction Network

    Article • Science, February 2004, American Association for the Advancement of Science

    Michael Chang

  47. Elg1 forms an alternative RFC complex important for DNA replication and genome integrity

    Article • The EMBO Journal, August 2003, Springer Science + Business Media

    Michael Chang

  48. A genome-wide screen for methyl methanesulfonate-sensitive mutants reveals genes required for S phase progression in the presence of DNA damage

    Article • Proceedings of the National Academy of Sciences, December 2002, Proceedings of the National Academy of Sciences

    Michael Chang

  49. Transcriptional Coregulation by the Cell Integrity Mitogen-Activated Protein Kinase Slt2 and the Cell Cycle Regulator Swi4

    Article • Molecular and Cellular Biology, October 2001, ASM Journals

    Michael Chang