All Stories

  1. Survival of dogs with myxomatous mitral valve disease administered preclinical pimobendan in comparison to pimobendan-naïve dogs from the onset of congestive heart failure

    Article • Journal of Veterinary Cardiology, August 2026, Elsevier

    Melanie Hezzell

  2. Prognostic value of plasma cortisol concentration in dogs with congestive heart failure

    Article • Journal of Veterinary Internal Medicine, March 2026, Oxford University Press (OUP)

    Jonathan Paul Mochel, Melanie Hezzell

  3. Anti‐desmoglein‐2 autoantibodies do not discriminate between UK boxer dogs with and without arrhythmogenic right ventricular cardiomyopathy

    Article • Veterinary Record, December 2025, Wiley

    Melanie Hezzell

  4. Exploring the Role of Transcriptomics, Proteomics, and Machine Learning in HPV Infection and Cardiovascular Disease

    Article • Biomedicines, November 2025, MDPI AG

    Melanie Hezzell

  5. Calculation of Myocardial Percentage Collagen, Mast Cell Count and Presence of Arteriosclerosis in Dogs With Myxomatous Mitral Valve Disease and Control Dogs–A Pilot Study

    Article • Veterinary Medicine and Science, November 2025, Wiley

    Melanie Hezzell

  6. Using a Spectrum of Care Approach to the Diagnosis and Staging of Canine Myxomatous Mitral Valve Disease

    Article • Advances in Small Animal Care, November 2025, Elsevier

    Melanie Hezzell

  7. Aged Zebrafish as a Spontaneous Model of Cardiac Valvular Disease

    Article • Aging Cell, October 2025, Wiley

    Melanie Hezzell

  8. Fatal consequences of feline coronavirus infection are associated with virus persistence and a distinct adaptive immune repertoire

    Article • October 2025, Cold Spring Harbor Laboratory Press

    Melanie Hezzell

  9. Rapid Screening of Anticoagulation Compounds for Biological Target-Associated Adverse Effects Using a Deep-Learning Framework in the Management of Atrial Fibrillation

    Article • Bioengineering, September 2025, MDPI AG

    Melanie Hezzell

  10. Sympathetic reactivity to physiological stress is associated with expanded cardiac extracellular volume in humans

    Article • BMC Medicine, July 2025, Springer Science + Business Media

    Melanie Hezzell

  11. Accelerometer-derived classifiers for early detection of degenerative joint disease in cats

    Article • The Veterinary Journal, June 2025, Elsevier

    Melanie Hezzell

  12. Management of preclinical mitral valve disease in dogs

    Article • In Practice, May 2025, Wiley

    Melanie Hezzell

  13. A Deep Learning Methodology for Screening New Natural Therapeutic Candidates for Pharmacological Cardioversion and Anticoagulation in the Treatment and Management of Atrial Fibrillation

    Article • Biomedicines, May 2025, MDPI AG

    Melanie Hezzell

  14. Transcriptomics, Proteomics and Bioinformatics in Atrial Fibrillation: A Descriptive Review

    Article • Bioengineering, February 2025, MDPI AG

    Melanie Hezzell

  15. Transcriptomics, Proteomics and Bioinformatics in Atrial Fibrillation: A Descriptive Review

    Article • January 2025, MDPI AG

    Melanie Hezzell

  16. Accelerometer-derived classifiers for early detection of degenerative joint disease in cats

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Melanie Hezzell

  17. Approach to dealing with acute heart failure in cats and dogs

    Article • In Practice, June 2023, Wiley

    Melanie Hezzell

  18. Comparisons of keratinocyte chemoattractant (KC) and monocyte chemoattractant protein-1 (MCP-1) between myxomatous mitral valve disease stages in dogs - a pilot study

    Article • March 2023, British Small Animal Veterinary Association

    Melanie Hezzell

  19. Prevalence of gastroesophageal reflux in dogs undergoing MRI for a thoracolumbar vertebral column pathology

    Article • Journal of Small Animal Practice, January 2023, Wiley

    Melanie Hezzell

  20. Heart rate variability during high‐speed treadmill exercise and recovery in Thoroughbred racehorses presented for poor performance

    Article • Equine Veterinary Journal, January 2023, Wiley

    Melanie Hezzell

  21. Improved Ca2+ release synchrony following selective modification of Itof and phase 1 repolarization in normal and failing ventricular myocytes

    Article • Journal of Molecular and Cellular Cardiology, November 2022, Elsevier

    Melanie Hezzell

  22. Validation of a focused echocardiographic training program in first opinion practice

    Article • Journal of Veterinary Internal Medicine, October 2022, Wiley

    Melanie Hezzell

  23. 21st century research—One Health, resilience, welfare, and disease

    Article • American Journal of Veterinary Research, August 2022, American Veterinary Medical Association (AVMA)

    Melanie Hezzell

  24. Training the equine respiratory muscles: Inspiratory muscle strength

    Article • Equine Veterinary Journal, July 2022, Wiley

    Melanie Hezzell

  25. The microvascular endothelial glycocalyx: An additional piece of the puzzle in veterinary medicine

    Article • The Veterinary Journal, July 2022, Elsevier

    Melanie Hezzell

  26. Circulating hyaluronan as a marker of endothelial glycocalyx damage in dogs with myxomatous mitral valve disease and dogs in a hypercoagulable state

    Article • The Veterinary Journal, July 2022, Elsevier

    Melanie Hezzell

  27. Training the equine respiratory muscles: Ultrasonographic measurement of muscle size

    Article • Equine Veterinary Journal, June 2022, Wiley

    Melanie Hezzell

  28. The prevalence of ultrasonographic gastrointestinal wall changes in dogs with acute pancreatitis - a retrospective study (2012-2020)

    Article • June 2022, British Small Animal Veterinary Association

    Melanie Hezzell

  29. Calculation of myocardial percentage collagen and mast cell count in dogs with myxomatous mitral valve disease and control dogs – a pilot study

    Article • June 2022, British Small Animal Veterinary Association

    Melanie Hezzell

  30. Three-Dimensional Printed Models of the Heart Represent an Opportunity for Inclusive Learning

    Article • Journal of Veterinary Medical Education, June 2022, University of Toronto Press (UTPress)

    Melanie Hezzell

  31. Prevalence of ultrasonographic gastrointestinal wall changes in dogs with acute pancreatitis: A retrospective study (2012‐2020)

    Article • Journal of Veterinary Internal Medicine, March 2022, Wiley

    Melanie Hezzell

  32. Effect of preoperative administration of atenolol to dogs with pulmonic stenosis undergoing interventional procedures

    Article • Journal of Veterinary Internal Medicine, March 2022, Wiley

    Melanie Hezzell

  33. Endothelial glycocalyx is damaged in diabetic cardiomyopathy: angiopoietin 1 restores glycocalyx and improves diastolic function in mice

    Article • Diabetologia, February 2022, Springer Science + Business Media

    Melanie Hezzell

  34. Transvalvular pulmonic stent angioplasty: procedural outcomes and complications in 15 dogs with pulmonic stenosis

    Article • Journal of Veterinary Cardiology, December 2021, Elsevier

    Melanie Hezzell

  35. Diagnostic Rounds: ECG 101

    Article • October 2021, British Small Animal Veterinary Association

    Melanie Hezzell

  36. Computed tomographic staging of dogs with anal sac adenocarcinoma

    Article • Journal of Small Animal Practice, October 2021, Wiley

    Melanie Hezzell

  37. Clinical findings associated with N‐terminal pro‐B‐type natriuretic peptide measurement in dogs and cats attending first opinion veterinary practices

    Article • Veterinary Record, September 2021, Wiley

    Melanie Hezzell

  38. Inspiratory muscle training for the treatment of dynamic upper airway collapse in racehorses: A preliminary investigation

    Article • The Veterinary Journal, September 2021, Elsevier

    Melanie Hezzell

  39. Evaluation of serum cardiac troponin‐ I concentrations for diagnosis of infective endocarditis in dogs

    Article • Journal of Veterinary Internal Medicine, August 2021, Wiley

    Melanie Hezzell

  40. DETERMINATION OF VERTEBRAL HEART SCALE AND ECHOCARDIOGRAPHIC MEASUREMENTS IN HEALTHY ANESTHETIZED AFRICAN WILD DOGS (LYCAON PICTUS) IN HUMAN CARE

    Article • Journal of Zoo and Wildlife Medicine, June 2021, American Association of Zoo Veterinarians

    Melanie Hezzell

  41. The equine diaphragm: A novel technique for repeatable ultrasound measurement

    Article • Veterinary Radiology & Ultrasound, August 2020, Wiley

    Melanie Hezzell

  42. Focused cardiac ultrasound and point‐of‐care NT‐proBNP assay in the emergency room for differentiation of cardiac and noncardiac causes of respiratory distress in cats

    Article • Journal of Veterinary Emergency and Critical Care, June 2020, Wiley

    Melanie Hezzell

  43. PetSavers

    Article • BSAVA Companion, June 2020, British Small Animal Veterinary Association

    Melanie Hezzell

  44. Monitoring congestive heart failure

    Article • In Practice, May 2020, Wiley

    Melanie Hezzell

  45. Long‐term biological variability and the generation of a new reference interval for plasma N‐terminal pro‐B‐type natriuretic peptide in Labrador retrievers

    Article • Journal of Small Animal Practice, April 2020, Wiley

    Dr David Allaway, Melanie Hezzell

  46. Investigation of focused cardiac ultrasound in the emergency room for differentiation of respiratory and cardiac causes of respiratory distress in dogs

    Article • Journal of Veterinary Emergency and Critical Care, March 2020, Wiley

    Melanie Hezzell

  47. Arrhythmogenic late Ca 2+ sparks in failing heart cells and their control by action potential configuration

    Article • Proceedings of the National Academy of Sciences, January 2020, Proceedings of the National Academy of Sciences

    Melanie Hezzell

  48. Measurements of echocardiographic indices and biomarkers of kidney injury in dogs with chronic kidney disease

    Article • The Veterinary Journal, January 2020, Elsevier

    Melanie Hezzell, JD Foster

  49. What can changes in serial measurements tell us about prognosis in myxomatous mitral valve disease?

    Article • Veterinary Record, September 2019, Wiley

    Melanie Hezzell

  50. Correction: Is treatment with pimobendan associated with an increased risk of arrhythmias in dogs with heart disease?

    Article • Veterinary Record, July 2019, Wiley

    Melanie Hezzell

  51. Exploring early life events including diet in cats presenting for gastrointestinal signs in later life

    Article • Veterinary Record, June 2019, BMJ

    Edward Hall, Melanie Hezzell

  52. A new hope? Transvascular pulmonic stents in six dogs with severe pulmonic stenosis

    Article • April 2019, British Small Animal Veterinary Association

    Melanie Hezzell

  53. Is treatment with pimobendan associated with an increased risk of arrhythmias in dogs with heart disease?

    Article • Veterinary Record, December 2018, Wiley

    Melanie Hezzell

  54. Effect of prespecified therapy escalation on plasma NT-proBNP concentrations in dogs with stable congestive heart failure due to myxomatous mitral valve disease

    Article • Journal of Veterinary Internal Medicine, September 2018, Wiley

    Melanie Hezzell

  55. Sample Size Determination for Evaluation of Time Domain Heart Rate Variability Indices in Canine Lameness

    Article • Journal of the American Animal Hospital Association, September 2018, American Animal Hospital Association

    Melanie Hezzell

  56. Pathology and prognosis of canine myxomatous mitral valve disease

    Article • In Practice, March 2018, BMJ

    Melanie Hezzell

  57. Treatment of dogs with compensated myxomatous mitral valve disease with spironolactone—a pilot study

    Article • Journal of Veterinary Cardiology, August 2017, Elsevier

    Melanie Hezzell

  58. Anodal stimulation in two dogs with transvenous permanent bipolar pacemakers

    Article • Journal of Veterinary Cardiology, December 2016, Elsevier

    Melanie Hezzell

  59. Differentiation of Cardiac from Noncardiac Pleural Effusions in Cats using Second‐Generation Quantitative and Point‐of‐Care NT ‐pro BNP Measurements

    Article • Journal of Veterinary Internal Medicine, January 2016, Wiley

    Melanie Hezzell

  60. Clinical Severity Score System in Dogs with Degenerative Mitral Valve Disease

    Article • Journal of Veterinary Internal Medicine, March 2015, Wiley

    Melanie Hezzell

  61. The effects of storage conditions on measurements of canine N-terminal pro-B-type natriuretic peptide

    Article • Journal of Veterinary Cardiology, March 2015, Elsevier

    Melanie Hezzell

  62. Associations between N-terminal procollagen type III, fibrosis and echocardiographic indices in dogs that died due to myxomatous mitral valve disease

    Article • Journal of Veterinary Cardiology, December 2014, Elsevier

    Melanie Hezzell

  63. Relationship of Plasma N-terminal Pro-brain Natriuretic Peptide Concentrations to Heart Failure Classification and Cause of Respiratory Distress in Dogs Using a 2nd Generation ELISA Assay

    Article • Journal of Veterinary Internal Medicine, October 2014, Wiley

    Melanie Hezzell

  64. Longitudinal Electrocardiographic Evaluation of Dogs with Degenerative Mitral Valve Disease

    Article • Journal of Veterinary Internal Medicine, February 2014, Wiley

    Melanie Hezzell

  65. Differentiating between feline pleural effusions of cardiac and non-cardiac origin using pleural fluid NT-proBNP concentrations

    Article • Journal of Small Animal Practice, November 2013, Wiley

    Melanie Hezzell

  66. Relationships between heart rate and age, bodyweight and breed in 10,849 dogs

    Article • Journal of Small Animal Practice, July 2013, Wiley

    Melanie Hezzell

  67. Relationships between heart rate and age, bodyweight and breed in 10,849 dogs

    Article • Journal of Small Animal Practice, May 2013, Wiley

    Melanie Hezzell

  68. Associations among serum N-terminal procollagen type III concentration, urinary aldosterone-to-creatinine ratio, and ventricular remodeling in dogs with myxomatous mitral valve disease

    Article • American Journal of Veterinary Research, November 2012, American Veterinary Medical Association (AVMA)

    Melanie Hezzell

  69. Selected echocardiographic variables change more rapidly in dogs that die from myxomatous mitral valve disease

    Article • Journal of Veterinary Cardiology, March 2012, Elsevier

    Melanie Hezzell

  70. Ultrasonographic measurement of flow-mediated vasodilation in dogs with chronic valvular disease

    Article • Journal of Veterinary Cardiology, March 2012, Elsevier

    Melanie Hezzell

  71. The Combined Prognostic Potential of Serum High-Sensitivity Cardiac Troponin I and N-Terminal pro-B-Type Natriuretic Peptide Concentrations in Dogs with Degenerative Mitral Valve Disease

    Article • Journal of Veterinary Internal Medicine, February 2012, Wiley

    Melanie Hezzell

  72. Gerbode defect associated with blunt trauma in a dog

    Article • Journal of Veterinary Cardiology, June 2011, Elsevier

    Melanie Hezzell

  73. The effect of protease inhibition on the temporal stability of NT-proBNP in feline plasma at room temperature

    Article • Journal of Veterinary Cardiology, March 2011, Elsevier

    Melanie Hezzell

  74. Laboratory evaluation of cardiac disease

    Article • British Small Animal Veterinary Association

    Melanie Hezzell

  75. Investigating the endothelial glycocalyx in health and disease in dogs

    Article • British Small Animal Veterinary Association

    Melanie Hezzell