All Stories

  1. Cytotoxic properties of a new organometallic platinum(ii) complex and its gold(i) heterobimetallic derivatives
  2. Exploring the potential of gold(iii) cyclometallated compounds as cytotoxic agents: variations on the C^N theme
  3. Selected cytotoxic gold compounds cause significant inhibition of 20S proteasome catalytic activities
  4. Inhibition of Na+/K+-ATPase and cytotoxicity of a few selected gold(III) complexes
  5. Protein Recognition of Gold-Based Drugs: 3D Structure of the Complex Formed When Lysozyme Reacts with Aubipyc
  6. Synthesis and Characterization of Palladium(II) and Platinum(II) Adducts and Cyclometalated Complexes of 6,6′-Dimethoxy-2,2′-bipyridine: C(sp3)–H and C(sp2)–H Bond Activations
  7. Structure–Activity Relationships in Cytotoxic AuI/AuIII Complexes Derived from 2-(2′-Pyridyl)benzimidazole
  8. Rollover‐Assisted C(sp2)C(sp3) Bond Formation
  9. Cyclometalated Complexes of Platinum(II) with 2‐Vinylpyridine
  10. Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(iii) compound
  11. Gold(i) compounds with lansoprazole-type ligands: synthesis, characterization and anticancer properties in vitro
  12. Assembly of symmetrical and unsymmetrical platinum(ii) rollover complexes with bidentate phosphine ligands
  13. Metal‐Based Compounds as Prospective Antileishmanial Agents: Inhibition of Trypanothione Reductase by Selected Gold Complexes
  14. Rollover Cyclometalation with 2-(2′-Pyridyl)quinoline
  15. ChemInform Abstract: Gold—Alkyne Complexes
  16. ChemInform Abstract: Gold—Alkene Complexes
  17. Mesoionic Complexes of Platinum(II) Derived from “Rollover” Cyclometalation: A Delicate Balance between Pt–C(sp3) and Pt–C(sp2) Bond Cleavage as a Result of Different Reaction Conditions
  18. The mode of action of anticancer gold-based drugs: a structural perspective
  19. Chemistry and biology of three representative gold(III) compounds as prospective anticancer agents
  20. Protein metalation by metal-based drugs: reactions of cytotoxic gold compounds with cytochrome c and lysozyme
  21. Gold–Alkene Complexes
  22. Gold–Alkyne Complexes
  23. Heterobimetallic Rollover Derivatives
  24. Gold(III) complexes with 2-substituted pyridines as experimental anticancer agents: Solution behavior, reactions with model proteins, antiproliferative properties
  25. Synthesis, Structural Characterization, Solution Behavior, and in Vitro Antiproliferative Properties of a Series of Gold Complexes with 2-(2′-Pyridyl)benzimidazole as Ligand: Comparisons of Gold(III) versus Gold(I) and Mononuclear versus Binuclear Deri...
  26. Medicinal gold compounds form tight adducts with the copper chaperone Atox-1: biological and pharmacological implications
  27. Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1
  28. Modification of HIV-1 reverse transcriptase and integrase activity by gold(III) complexes in direct biochemical assays
  29. Proteomic analysis of ovarian cancer cell responses to cytotoxic gold compounds
  30. 2D-DIGE analysis of ovarian cancer cell responses to cytotoxic gold compounds
  31. Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro
  32. Platinum(II)-Cyclometalated “Roll-over” Complexes with a Chiral Pinene-Derived 2,2′-Bipyridine
  33. Structural and solution chemistry, protein binding and antiproliferative profiles of gold(I)/(III) complexes bearing the saccharinato ligand
  34. Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(iii) compounds studied with combined mass spectrometry and biochemical assays
  35. Mechanistic studies on two dinuclear organogold(iii) compounds showing appreciable antiproliferative properties and a high redox stability
  36. ChemInform Abstract: Chemistry of Gold(III) Complexes with Nitrogen and Oxygen Ligands
  37. [Au2(phen2Me)2(μ-O)2](PF6)2, a Novel Dinuclear Gold(III) Complex Showing Excellent Antiproliferative Properties
  38. ChemInform Abstract: Step by Step Palladium‐Mediated Syntheses of New 2‐(Pyridin‐2‐yl)‐6‐R‐nicotinic Acids and Esters.
  39. Dinuclear Gold(III) Complexes as Potential Anticancer Agents: Structure, Reactivity and Biological Profile of a Series of Gold(III) Oxo-Bridged Derivatives~!2009-12-08~!2010-01-15~!2010-03-25~!
  40. Intramolecular C(sp2)−H Bond Activation in 6,6′-Dimethoxy-2,2′-Bipyridine with Gold(III). Crystal and Molecular Structure of the First N′,C(3) “Rollover” Cycloaurated Derivative
  41. Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study
  42. Gold(iii) six-membered N⁁C⁁N pincer complexes: synthesis, structure, reactivity and theoretical calculations
  43. Step by step palladium mediated syntheses of new 2-(pyridin-2-yl)-6-R-nicotinic acids and esters
  44. Gold(III) Adducts with Chiral Pyridinyl-Oxazolines. Synthesis, Reactivity of the Coordinated Ligands, and Structural Characterizations
  45. N^N^C platinum(II) and palladium(II) cyclometallates of 6,6′-diphenyl-2,2′-bipyridine, L: Crystal and molecular structure of [Pd(L–H)Cl]
  46. Potential antitumor gold drugs:DFT and XANES studies of local atomic and electronic structure
  47. Large Effect of a Small Substitution: Competition of Dehydration with Charge Retention and Coulomb Explosion in Gaseous [(bipyR)Au(μ-O)2Au(bipyR)]2+ Dications
  48. Gold(III) adducts of 2-vinyl- and 2-ethylpyridine and cyclometallated derivatives of 2-vinylpyridine: Crystal structure of the cyclometallated derivative [Au(k2-C,N–CH2CH(Cl)–C5H4N)(PPh3)Cl][PF6]
  49. Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study
  50. Chemistry of Gold(III) Complexes with Nitrogen and Oxygen Ligands
  51. Cyclometalation of 2,2′-Bipyridine. Mono- and Dinuclear C,N Platinum(II) Derivatives
  52. Outstanding plasmodicidal properties within a small panel of metallic compounds: Hints for the development of new metal-based antimalarials
  53. Reactivity of 1,3-bis(2-pyridyl)benzene, N⁁CH⁁N, with gold(iii) chlorides: salts, adducts and cyclometalated pincer derivatives. Crystal and molecular structures of [HN⁁CH⁁N][AuCl4], [Au(N⁁C⁁N)Cl][PF6] and [Au(N⁁C⁁N)Cl(PPh3)2][PF6]
  54. N,C “Rollover” Cyclometalated Platinum(II) Hydrides: Mono- and Polynuclear Derivatives
  55. Structural Characterization, Solution Studies, and DFT Calculations on a Series of Binuclear Gold(III) Oxo Complexes: Relationships to Biological Properties
  56. Diimine supported group 10 hydroxo, oxo, amido, and imido complexes
  57. Cyclometalated Platinum(II) Hydrides with Nitrogen Ligands
  58. Dinuclear platinum(II) complexes with bridging twofold deprotonated 2,2′:6′,2″-terpyridine. New molecules with a 3,5-diplatinated-pyridyl inner core: [Pt2(terpy-2H)(Me)2(L)2], [Pt2(terpy-2H)(X)2(L)2] and [Pt2(terpy-2H)(H)2(L)2] (L=neutral ligand; X=hal...
  59. Structural and Solution Chemistry, Antiproliferative Effects, and DNA and Protein Binding Properties of a Series of Dinuclear Gold(III) Compounds with Bipyridyl Ligands
  60. The first pincer-aryl [M–(NCN)] complexes {M=Pd(II); Pt(II)} with chiral pyridine donors: Synthesis and catalytic activity in C–C bond formation
  61. Dinuclear C,N,C Cyclometalated Platinum Derivatives with Bridging Delocalized Ligands. Fourfold Deprotonation of 6,6‘-Diphenyl-2,2‘-bipyridine, H4L, Promoted by “Pt(R)2” Fragments (R = Me, Ph). Crystal Structures of [Pt2
  62. Synthesis and properties of gold alkene complexes. Crystal structure of [Au(bipyoXyl)(η2-CH2CHPh)](PF6) and DFT calculations on the model cation [Au(bipy)(η2-CH2CH2)]+<...
  63. Reactions of Gold(III) Oxo Complexes with Cyclic Alkenes
  64. Reactions of Gold(III) Oxo Complexes with Cyclic Alkenes
  65. Mechanisms of Cytotoxicity of Selected Organogold(III) Compounds
  66. Synthesis of the First C-2 Cyclopalladated Derivatives of 1,3-Bis(2-pyridyl)benzene. Crystal Structures of [Hg(N-C-N)Cl], [Pd(N-C-N)Cl], and [Pd2(N-C-N)2(μ-OAc)]2[Hg2Cl6]. Catalytic Activity in the...
  67. Solution chemistry and cytotoxic properties of novel organogold(III) compounds
  68. Dinuclear, Tricyclometallated Platinum(II) Derivatives − Substitution Reactions and Reactivity of the Platinum−Carbon Bonds
  69. Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions
  70. Effect of 5-Me substituent(s) on the catalytic activity of palladium(II) 2,2′-bipyridine complexes in CO/4-tert-butylstyrene copolymerization
  71. Reaction of gold(iii) oxo complexes with alkenes. Synthesis of unprecedented gold alkene complexes, [Au(N,N)(alkene)][PF6]. Crystal structure of [Au(bipyip)(η2-CH2CHPh)][PF6] (bipy...
  72. Reactions of gold(III) complexes with serum albumin
  73. Activation of a C−H Bond in a Pyridine Ring. Reaction of 6-Substituted 2,2‘-Bipyridines with Methyl and Phenyl Platinum(II) Derivatives:  N‘,C(3)-“Rollover” Cyclometalation
  74. Reactivity of 6-(2-tolyl)- and 6-(2,6-xylyl)-2,2′-bipyridines with palladium(II) derivatives. Selective C(sp3)H vs. C(sp2)H activation
  75. Synthesis and Characterization of Mononuclear Amidogold(III) Complexes − Crystal Structure of [Au(N2C10H7(CMe2C6H4)‐6](NHC6H3Me2‐2,6)][PF...
  76. Gold(I) and Gold(III) Complexes with Anionic Oxygen Donor Ligands: Hydroxo, Oxo and Alkoxo Complexes
  77. Metallation of Unactivated Methyl Groups − Platinum(II) Derivatives with 6-Alkyl-2,2′-bipyridines
  78. New complexes of palladium(II) with chelating heterocyclic nitrogen ligands.
  79. Gold(III) Complexes with Bipyridyl Ligands:  Solution Chemistry, Cytotoxicity, and DNA Binding Properties
  80. Gold(I) and gold(III) complexes with anionic oxygen donor ligands: hydroxo, oxo and alkoxo complexes
  81. Reactivity of Ph2P(O)py-2 with Platinum(II) Alkyl Derivatives − Building-up of a Chiral Phosphorus Atom through C,N-Cyclometallation
  82. Multiple C−H Bond Activation. Threefold-Deprotonated 6-Phenyl-2,2‘-bipyridine as a Bridging Ligand in Dinuclear Platinum(II) Derivatives
  83. Synthesis and Molecular Structure of [Pd{CH2CH2C(O)Me}(HL)][BAr‘4] (HL = 6-Me-2,2‘-bipyridine, Ar‘ = 3,5-(CF3)2C6H3), an Intermediate Relevant to Ethene/CO Copolymerization
  84. Electrochemical behaviour of cyclometallated gold(III) complexes. Evidence of transcyclometallation in the fate of electroreduced species
  85. Unprecedented Behavior of 2,2‘:6‘,2‘ ‘-Terpyridine:  Dinuclear Platinum(II) Derivatives with a New N,C∧C,N Bridging Ligand
  86. Electrochemical properties of gold(III) complexes with 2,2′-bipyridine and oxygen ligands
  87. Neutral and Cationic Methyl Complexes of Platinum(II) with 6-Substituted 2,2′-Bipyridines: Synthesis, Characterisation and Reactivity with Carbon Monoxide − Molecular Structures of [PtCl(methyl)(6-ethyl-2,2′-bipyridine)] and of [Pt(methyl)(acetonitrile...
  88. Cyclopalladation of 6-Substituted-2,2‘-bipyridines. Metalation of Unactivated Methyl Groups vs Aromatic C−H Activation
  89. Gold(III) derivatives with anionic oxygen ligands: mononuclear hydroxo, alkoxo and acetato complexes. Crystal structure of [Au(bpy)(OMe)2][PF6]
  90. Palladium(II) and platinum(II)-C(3)-substituted 2,2′-bipyridines
  91. Replacement of the chloride ligand in [Au(C,N,N)Cl][PF6] cyclometallated complexes by C, N, O and S donor anionic ligands
  92. Cyclometallated derivatives of rhodium(III). Activation of C(sp3)–H vs. C(sp2)–H bonds
  93. Gold(III) derivatives with C(4)-aurated 1-phenylpyrazole
  94. C(3) aurated 1,4-benzodiazepin-2-ones. Synthesis and characterization. Crystal structure of (L)Au[P(C6H4CH3-4)3] (HL=7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one, DIAZEPAM)
  95. The first gold(III) dinuclear cyclometallated derivatives with a single oxo bridge
  96. Palladium(II) and platinum(II) derivatives with N,O ligands
  97. μ-Oxo and alkoxo complexes of gold(III) with 6-alkyl-2,2′-bipyridines. Synthesis, characterization and X-ray structures
  98. Synthesis and characterization of gold(III) adducts and cyclometallated derivatives with 6-benzyl- and 6-alkyl-2,2′-bipyridines
  99. Synthesis and characterization of square-planar palladium(II), platinum(II) and rhodium(I) complexes with a chiral pyridylphosphine hybrid ligand
  100. Cyclometallated derivatives of platinum(II) derived from 6-(tert-butyl)-2,2′-bipyridine (HL). Crystal and molecular structure of [Pt(L)CI]
  101. Synthesis and characterization of gold(III) adducts and cyclometallated derivatives with 2-substituted pyridines. Crystal structure of [Au{NC5H4(CMe2C6H4)-2}Cl2]
  102. Six-membered cyclometallated derivatives of platinum(II) derived from 2-benzylpyridines. Crystal and molecular structure of [Pt(L)(Ph3P)Cl] (HL = 2-(1-methylbenzyl)pyridine)
  103. Cyclometallated derivatives of platinum(II) derived from 1,4-benzodiazepin-2-ones. Crystal and molecular structure of Pt(L)(HL)Cl(HL7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one, DIAZEPAM), a molecule containing a neutral and a dep...
  104. Cyclometallated derivatives of palladium(II) and platinum(II) derived from 6-t-butyl-2,2′-bipyridine
  105. FAB mass spectrometry of Au(I) complexes with 1,4-benzodiazepin-2-ones
  106. ChemInform Abstract: Unusual Platinum Hydrides with Nitrogen Ligands.
  107. Cyclometallated derivatives of palladium(II) with 1,4-benzodiazepin-2-ones. Crystal structure of (L-H)Pd(PPh3)Cl·CHCl3 (L = Prazepam: 7-chloro-1-cyclopropylmethyl-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one). Synthesis of isoindolo[2,1-d][1,4]benzo...
  108. Unusual platinum hydrides with nitrogen ligands
  109. Fast‐Atom bombardment mass spectrometry and collisional spectroscopy in the structural characterization of underivatized 1,4‐benzodiazepines
  110. Mono and dinuclear gold(I) complexes with neutral and deprotonated 1,4-benzodiazepin-2-ones. Crystal and molecular structure of (L-H)Au(PPh3)·Et2O, where L = 1,3-dihydro-7-nitro-5-phenyl-2H-1,4-benzodiazepin-2-one, nitrazepam
  111. Reaction of platinum(II) derivatives with bis(pyrazolyl)propane. cleavage of a C(sp3)-N bond in a bis(pyrazolyl)alkane promoted by platinum(II) derivatives. crystal structure of cis-PT(pzH)2Cl2 (pzH = pyrazole)
  112. FAB mass spectrometry of palladium(II) derivatives with 1,4-benzodiazepin-2-ones: Evidence of the stability of cyclometallated species
  113. Reactions of carbon monoxide with cyclometallated complexes of palladium(II) and platinum(II) derived from a chiral alkylbipyridine ligand
  114. 1,1'-Bis(diphenylphosphino)ferrocene complexes of platinum(II) and platinum(I). Crystal and molecular structure of [(L-L)Pt(.mu.-H)(.mu.-CO)Pt(L-L)][BF4].0.5H2O, where L-L = Fe(.eta.5-C5H4PPh2)2
  115. Adducts and cyclometallated derivatives of palladium(II) with some 1,4-benzodiazepin-2-ones. Crystal and molecular structure of trans-dichlorobis[7-chloro-1-(cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one] palladium(II)
  116. Preparation and characterization of palladium(II) and platinum(II) complexes with bis(pyrazolyl)alkanes. crystal and molecular structures of [Pd2(pz)22][BF4]2 and of [PdCl2{(CH3)2C(pz)2}] (pzH = pyrazole), a new example of a Pd⋯HC agostic interaction
  117. Palladium(II) and platinum(II) derivatives with chiral 2,2′-bipyridines. X-ray structure of C18H15ClN2Pd; C- and N-intramolecular coordination in a six-membered metallacycle
  118. Synthesis and characterization of gold(III) complexes of 1,4-benzodiazepin-2-ones. Crystal structure of trichloro-[7-chloro-1-(cyclopropylmethyl)-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one]gold(III)