All Stories

  1. Interaction of Platinum-based Drugs with Proteins: An Overview of Representative Crystallographic Studies

    Article • Current Topics in Medicinal Chemistry, January 2021, Bentham Science Publishers

    Professor Antonello Merlino

  2. Mimetics of suppressor of cytokine signaling 3: Novel potential therapeutics in triple breast cancer

    Article • International Journal of Cancer, August 2018, Wiley

    Daniela Marasco, Professor Antonello Merlino

  3. Five-Coordinate Platinum(II) Compounds Containing Sugar Ligands: Synthesis, Characterization, Cytotoxic Activity, and Interaction with Biological Macromolecules

    Article • Inorganic Chemistry, March 2018, American Chemical Society (ACS)

    Professor Antonello Merlino

  4. A case of extensive protein platination: the reaction of lysozyme with a Pt(ii)–terpyridine complex

    Article • Dalton Transactions, January 2018, Royal Society of Chemistry

    Professor Antonello Merlino

  5. Exploring the interactions between model proteins and Pd(ii) or Pt(ii) compounds bearing chargedN,N-pyridylbenzimidazole bidentate ligands by X-ray crystallography

    Article • Dalton Transactions, January 2018, Royal Society of Chemistry

    Professor Antonello Merlino

  6. Cisplatin Binding Sites in Human H-Chain Ferritin

    Article • Inorganic Chemistry, July 2017, American Chemical Society (ACS)

    Professor Antonello Merlino

  7. X-ray Structure of the Carboplatin-Loaded Apo-Ferritin Nanocage

    Article • ACS Medicinal Chemistry Letters, March 2017, American Chemical Society (ACS)

    Professor Antonello Merlino

  8. Principles and methods used to grow and optimize crystals of protein–metallodrug adducts, to determine metal binding sites and to assign metal ligands

    Article • Metallomics, January 2017, Oxford University Press (OUP)

    Professor John Richard Helliwell, Professor Antonello Merlino

  9. A driving force for polypeptide and protein collapse

    Article • Physical Chemistry Chemical Physics, January 2017, Royal Society of Chemistry

    Professor Antonello Merlino

  10. Ferritin nanocages loaded with gold ions induce oxidative stress and apoptosis in MCF-7 human breast cancer cells

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Professor Antonello Merlino

  11. Protein metalation by metal-based drugs: X-ray crystallography and mass spectrometry studies

    Article • Chemical Communications, January 2017, Royal Society of Chemistry

    Professor Antonello Merlino

  12. Ru-Based CO releasing molecules with azole ligands: interaction with proteins and the CO release mechanism disclosed by X-ray crystallography

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Professor Antonello Merlino

  13. {Ru(CO)x}-Core complexes with benzimidazole ligands: synthesis, X-ray structure and evaluation of anticancer activity in vivo

    Article • Dalton Transactions, January 2017, Royal Society of Chemistry

    Professor Antonello Merlino

  14. Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts

    Article • Journal of Inorganic Biochemistry, December 2015, Elsevier

    Professor Antonello Merlino

  15. Platinum(II) Complexes with O,S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding

    Article • Inorganic Chemistry, August 2015, American Chemical Society (ACS)

    Professor Antonello Merlino

  16. Structural evidences for a secondary gold binding site in the hydrophobic box of lysozyme

    Article • BioMetals, June 2015, Springer Science + Business Media

    Professor Antonello Merlino

  17. Platinated oligomers of bovine pancreatic ribonuclease: Structure and stability

    Article • Journal of Inorganic Biochemistry, May 2015, Elsevier

    Professor Antonello Merlino

  18. Missing gold atoms in lysozyme crystals used to grow gold nanoparticles

    Article • Nature Nanotechnology, April 2015, Springer Science + Business Media

    Professor Antonello Merlino

  19. α-Thalassemia Associated with Hb Instability: A Tale of Two Features. The Case of Hb Rogliano or α1 Cod 108(G15)Thr→Asn and Hb Policoro or α2 Cod 124(H7)Ser→Pro.

    Article • PLoS ONE, March 2015, PLOS

    Professor Antonello Merlino

  20. The X-ray structure of the primary adducts formed in the reaction between cisplatin and cytochrome c

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Professor Antonello Merlino

  21. Fusion of raft-like lipid bilayers operated by a membranotropic domain of the HSV-type I glycoprotein gH occurs through a cholesterol-dependent mechanism

    Article • Soft Matter, January 2015, Royal Society of Chemistry

    Professor Antonello Merlino

  22. Cisplatin binding to human serum albumin: a structural study

    Article • Chemical Communications, January 2015, Royal Society of Chemistry

    Professor Antonello Merlino

  23. Oxaliplatin vs. cisplatin: competition experiments on their binding to lysozyme

    Article • Dalton Transactions, January 2015, Royal Society of Chemistry

    Professor Antonello Merlino

  24. Interaction of anticancer Ru(iii) complexes with single stranded and duplex DNA model systems

    Article • Dalton Transactions, January 2015, Royal Society of Chemistry

    Professor Antonello Merlino

  25. γ-Glutamyl transpeptidase architecture: Effect of extra sequence deletion on autoprocessing, structure and stability of the protein from Bacillus licheniformis

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, December 2014, Elsevier

    Professor Antonello Merlino

  26. Interactions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(iii) compound Auoxo3

    Article • Dalton Transactions, September 2014, Royal Society of Chemistry

    Professor Antonello Merlino

  27. Interaction between Proteins and Ir Based CO Releasing Molecules: Mechanism of Adduct Formation and CO Release

    Article • Inorganic Chemistry, September 2014, American Chemical Society (ACS)

    Professor Antonello Merlino

  28. Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, September 2014, Elsevier

    Professor Antonello Merlino

  29. Protein Recognition of Gold-Based Drugs: 3D Structure of the Complex Formed When Lysozyme Reacts with Aubipyc

    Article • ACS Medicinal Chemistry Letters, August 2014, American Chemical Society (ACS)

    Professor Maria Agostina Cinellu, Professor Antonello Merlino

  30. Interactions between Anticancer trans-Platinum Compounds and Proteins: Crystal Structures and ESI-MS Spectra of Two Protein Adducts of trans-(Dimethylamino)(methylamino)dichloridoplatinum(II)

    Article • Inorganic Chemistry, July 2014, American Chemical Society (ACS)

    Dr ADORACION GOMEZ QUIROGA, Professor Antonello Merlino

  31. Comments onStructural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1.9 Å resolutionby P. Rameshet al.(2013).J. Synchrotron Rad.20, 843–847

    Article • Journal of Synchrotron Radiation, June 2014, International Union of Crystallography

    Alessandro Vergara, Professor Antonello Merlino

  32. Unusual Structural Features in the Lysozyme Derivative of the Tetrakis(acetato)chloridodiruthenium(II,III) Complex

    Article • Angewandte Chemie, May 2014, Wiley

    Professor Antonello Merlino

  33. Cisplatin Binding to Proteins: Molecular Structure of the Ribonuclease A Adduct

    Article • Inorganic Chemistry, April 2014, American Chemical Society (ACS)

    Professor Antonello Merlino

  34. Molecular bases of protein halotolerance

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, April 2014, Elsevier

    Professor Antonello Merlino

  35. Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, March 2014, Elsevier

    Professor Antonello Merlino

  36. A regular thymine tetrad and a peculiar supramolecular assembly in the first crystal structure of an all-LNA G-quadruplex

    Article • Acta Crystallographica Section D Biological Crystallography, January 2014, International Union of Crystallography

    Associate professor Filomena Sica, Professor Antonello Merlino

  37. Ruthenium metalation of proteins: the X-ray structure of the complex formed between NAMI-A and hen egg white lysozyme

    Article • Dalton Transactions, January 2014, Royal Society of Chemistry

    Professor Antonello Merlino

  38. Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(iii) compound

    Article • Metallomics, January 2014, Oxford University Press (OUP)

    Alessandro Vergara, Professor Maria Agostina Cinellu, Professor Antonello Merlino

  39. The X-ray structure of the complex formed in the reaction between oxaliplatin and lysozyme

    Article • Chemical Communications, January 2014, Royal Society of Chemistry

    Professor Antonello Merlino

  40. Structural modifications induced by the switch from an endogenous bis-histidyl to an exogenous cyanomet hexa-coordination in a tetrameric haemoglobin

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Alessandro Vergara, Professor Antonello Merlino

  41. Peculiar Features in the Crystal Structure of the Adduct Formed betweencis-PtI2(NH3)2and Hen Egg White Lysozyme

    Article • Inorganic Chemistry, November 2013, American Chemical Society (ACS)

    Dr ADORACION GOMEZ QUIROGA, Professor Antonello Merlino

  42. Duplex–quadruplex motifs in a peculiar structural organization cooperatively contribute to thrombin binding of a DNA aptamer

    Article • Acta Crystallographica Section D Biological Crystallography, November 2013, International Union of Crystallography

    Professor Antonello Merlino

  43. Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer

    Article • FEBS Journal, November 2013, Wiley

    Associate professor Filomena Sica, Professor Antonello Merlino

  44. The structure of the CD3 ζζ transmembrane dimer in POPC and raft-like lipid bilayer: A molecular dynamics study

    Article • Biochimica et Biophysica Acta (BBA) - Biomembranes, November 2013, Elsevier

    Professor Antonello Merlino

  45. The multiple forms of bovine seminal ribonuclease: Structure and stability of a C‐terminal swapped dimer

    Article • FEBS Letters, October 2013, Wiley

    Associate professor Filomena Sica, Professor Antonello Merlino

  46. Structural and functional relationships of natural and artificial dimeric bovine ribonucleases: New scaffolds for potential antitumor drugs

    Article • FEBS Letters, October 2013, Wiley

    Professor Antonello Merlino

  47. Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase

    Article • Acta Crystallographica Section D Biological Crystallography, September 2013, International Union of Crystallography

    Professor Antonello Merlino

  48. Investigating the Ruthenium Metalation of Proteins: X-ray Structure and Raman Microspectroscopy of the Complex between RNase A and AziRu

    Article • Inorganic Chemistry, September 2013, American Chemical Society (ACS)

    Alessandro Vergara, Professor Antonello Merlino

  49. Reaction of Hg2+ Insertion into Cysteine Pairs Within Bovine Insulin Crystals Followed via Raman Spectroscopy

    Article • Journal of Solution Chemistry, September 2013, Springer Science + Business Media

    Alessandro Vergara, Professor Antonello Merlino

  50. Role of tertiary structures on the Root effect in fish hemoglobins

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, September 2013, Elsevier

    Alessandro Vergara, Professor Antonello Merlino

  51. Molecular basis of the NO trans influence in quaternary T‐state human hemoglobin: A computational study

    Article • FEBS Letters, June 2013, Wiley

    Alessandro Vergara, Professor Antonello Merlino

  52. An Overview of Biological Macromolecule Crystallization

    Article • International Journal of Molecular Sciences, May 2013, MDPI AG

    Alessandro Vergara, Associate professor Filomena Sica, Professor Antonello Merlino

  53. Heterogeneous nucleation helps the search for initial crystallization conditions of γ-glutamyl transpeptidase fromBacillus licheniformis

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, May 2013, International Union of Crystallography

    Professor Antonello Merlino

  54. A novel interdomain interface in crystallins: structural characterization of the βγ-crystallin fromGeodia cydoniumat 0.99 Å resolution

    Article • Acta Crystallographica Section D Biological Crystallography, May 2013, International Union of Crystallography

    Alessandro Vergara, Professor Antonello Merlino

  55. Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu

    Article • Inorganic Chemistry, March 2013, American Chemical Society (ACS)

    Alessandro Vergara, Professor Antonello Merlino

  56. The mode of action of anticancer gold-based drugs: a structural perspective

    Article • Chemical Communications, January 2013, Royal Society of Chemistry

    Alessandro Vergara, Professor Maria Agostina Cinellu, Professor Antonello Merlino

  57. Cholesterol modulates the fusogenic activity of a membranotropic domain of the FIV glycoprotein gp36

    Article • Soft Matter, January 2013, Royal Society of Chemistry

    Professor Antonello Merlino

  58. Bovine Seminal Ribonuclease and Its Special Features: When Two is Better Than One

    Article • January 2013, Springer Science + Business Media

    Professor Antonello Merlino

  59. Effect of NaCl on the conformational stability of the thermophilic γ-glutamyltranspeptidase from Geobacillus thermodenitrificans: Implication for globular protein halotolerance

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, January 2013, Elsevier

    Professor Antonello Merlino

  60. Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study

    Article • Acta Crystallographica Section D Biological Crystallography, December 2012, International Union of Crystallography

    Alessandro Vergara, Dr Florian Sven Nico Dworkowski, Professor Antonello Merlino

  61. High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity

    Article • Nucleic Acids Research, June 2012, Oxford University Press (OUP)

    Professor Antonello Merlino

  62. Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease

    Article • Biochimie, May 2012, Elsevier

    Associate professor Filomena Sica, Professor Antonello Merlino

  63. γ-Glutamyltranspeptidases: sequence, structure, biochemical properties, and biotechnological applications

    Article • Cellular and Molecular Life Sciences, April 2012, Springer Science + Business Media

    Professor Antonello Merlino

  64. Role of the tertiary and quaternary structure in the formation of bis-histidyl adducts in cold-adapted hemoglobins

    Article • Biochimie, April 2012, Elsevier

    Alessandro Vergara, Professor Antonello Merlino

  65. Exploring the unfolding mechanism of γ-glutamyltranspeptidases: The case of the thermophilic enzyme from Geobacillus thermodenitrificans

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, April 2012, Elsevier

    Professor Antonello Merlino

  66. Increasing the X-ray Diffraction Power of Protein Crystals by Dehydration: The Case of Bovine Serum Albumin and a Survey of Literature Data

    Article • International Journal of Molecular Sciences, March 2012, MDPI AG

    Professor Antonello Merlino

  67. Identification of an active dimeric intermediate populated during the unfolding process of the cambialistic superoxide dismutase from Streptococcus mutans

    Article • Biochimie, March 2012, Elsevier

    Alessandro Vergara, Professor Antonello Merlino

  68. ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Alessandro Vergara, Professor Antonello Merlino

  69. Destabilization of Lipid Membranes by a Peptide Derived from Glycoprotein gp36 of Feline Immunodeficiency Virus: A Combined Molecular Dynamics/Experimental Study

    Article • The Journal of Physical Chemistry B, December 2011, American Chemical Society (ACS)

    Professor Antonello Merlino

  70. Improving Protein Crystal Quality by the Without-Oil Microbatch Method: Crystallization and Preliminary X-ray Diffraction Analysis of Glutathione Synthetase from Pseudoalteromonas haloplanktis

    Article • International Journal of Molecular Sciences, September 2011, MDPI AG

    Alessandro Vergara, Professor Antonello Merlino

  71. Thrombin–aptamer recognition: a revealed ambiguity

    Article • Nucleic Acids Research, June 2011, Oxford University Press (OUP)

    Professor Antonello Merlino

  72. Occurrence and formation of endogenous histidine hexa‐coordination in cold‐adapted hemoglobins

    Article • IUBMB Life, April 2011, Wiley

    Alessandro Vergara, Professor Antonello Merlino

  73. Protonation of histidine 55 affects the oxygen access to heme in the alpha chain of the hemoglobin from the Antarctic fish Trematomus bernacchii

    Article • IUBMB Life, March 2011, Wiley

    Alessandro Vergara, Professor Antonello Merlino

  74. A novel ErbB2 epitope targeted by human antitumor immunoagents

    Article • FEBS Journal, March 2011, Wiley

    Professor Antonello Merlino

  75. Gene cloning and protein expression of γ-glutamyltranspeptidases from Thermus thermophilus and Deinococcus radiodurans: comparison of molecular and structural properties with mesophilic counterparts

    Article • Extremophiles, February 2011, Springer Science + Business Media

    Professor Antonello Merlino

  76. A new RNase sheds light on the RNase/angiogenin subfamily from zebrafish

    Article • Biochemical Journal, December 2010, Portland Press Ltd.

    Professor Antonello Merlino

  77. Structure and flexibility in cold-adapted iron superoxide dismutases: The case of the enzyme isolated from Pseudoalteromonas haloplanktis

    Article • Journal of Structural Biology, December 2010, Elsevier

    Alessandro Vergara, Professor Antonello Merlino

  78. An evolutionary conserved motif is responsible for Immunoglobulin heavy chain packing in the B cell membrane

    Article • Molecular Phylogenetics and Evolution, December 2010, Elsevier

    Professor Antonello Merlino

  79. Crystallization, preliminary X-ray diffraction studies and Raman microscopy of the major haemoglobin from the sub-Antarctic fishEleginops maclovinusin the carbomonoxy form

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, October 2010, International Union of Crystallography

    Alessandro Vergara, Professor Antonello Merlino

  80. An Order-Disorder Transition Plays a Role in Switching Off the Root Effect in Fish Hemoglobins

    Article • Journal of Biological Chemistry, October 2010, Elsevier

    Professor Antonello Merlino

  81. Crystallization and preliminary X-ray analysis of the complex of human α-thrombin with a modified thrombin-binding aptamer

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2010, International Union of Crystallography

    Professor Antonello Merlino

  82. A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, June 2010, Elsevier

    Professor Antonello Merlino

  83. Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity

    Article • Biochimie, May 2010, Elsevier

    Professor Antonello Merlino

  84. Free-Energy Profile for CO Binding to Separated Chains of Human and Trematomus newnesi Hemoglobin: Insights from Molecular Dynamics Simulations and Perturbed Matrix Method

    Article • The Journal of Physical Chemistry B, April 2010, American Chemical Society (ACS)

    Alessandro Vergara, Professor Antonello Merlino

  85. Correlation between Hemichrome Stability and the Root Effect in Tetrameric Hemoglobins

    Article • Biophysical Journal, August 2009, Elsevier

    Alessandro Vergara, Professor Antonello Merlino

  86. Combined crystallographic and spectroscopic analysis of Trematomus bernacchii hemoglobin highlights analogies and differences in the peculiar oxidation pathway of Antarctic fish hemoglobins

    Article • Biopolymers, April 2009, Wiley

    Alessandro Vergara, Professor Antonello Merlino

  87. Toward an antitumor form of bovine pancreatic ribonuclease: The crystal structure of three noncovalent dimeric mutants

    Article • Biopolymers, March 2009, Wiley

    Alessandro Vergara, Professor Antonello Merlino

  88. The bis-histidyl complex in hemoproteins: A detailed conformational analysis of database protein structures and the case of Antarctic fish hemoglobins

    Article • Marine Genomics, March 2009, Elsevier

    Alessandro Vergara, Associate professor Filomena Sica, Professor Antonello Merlino

  89. Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant

    Article • Protein Science, December 2008, Wiley

    Associate professor Filomena Sica, Professor Antonello Merlino

  90. Structure and dimerization of the teleost transmembrane immunoglobulin region

    Article • Journal of Molecular Graphics and Modelling, October 2008, Elsevier

    Professor Antonello Merlino

  91. Correlation between Raman and X-ray crystallography data of (Pro-Pro-Gly)10

    Article • Biophysical Chemistry, September 2008, Elsevier

    Alessandro Vergara, Associate professor Filomena Sica, Professor Antonello Merlino

  92. Spectroscopic and Crystallographic Characterization of a Tetrameric Hemoglobin Oxidation Reveals Structural Features of the Functional Intermediate Relaxed/Tense State

    Article • Journal of the American Chemical Society, July 2008, American Chemical Society (ACS)

    Alessandro Vergara, Professor Antonello Merlino

  93. Crystallization and Preliminary X-Ray Diffraction Studies of a Psychrophilic Iron Superoxide Dismutase from Pseudoalteromonas haloplanktis

    Article • Protein and Peptide Letters, May 2008, Bentham Science Publishers

    Alessandro Vergara, Associate professor Filomena Sica, Professor Antonello Merlino

  94. The Buried Diversity of Bovine Seminal Ribonuclease: Shape and Cytotoxicity of the Swapped Non-covalent Form of the Enzyme

    Article • Journal of Molecular Biology, February 2008, Elsevier

    Professor Antonello Merlino

  95. A novel method for detection of selenomethionine incorporation in protein crystalsviaRaman microscopy

    Article • Acta Crystallographica Section D Biological Crystallography, January 2008, International Union of Crystallography

    Alessandro Vergara, Professor Antonello Merlino

  96. Structural Characterization of Ferric Hemoglobins from Three Antarctic Fish Species of the Suborder Notothenioidei

    Article • Biophysical Journal, October 2007, Elsevier

    Alessandro Vergara, Professor Antonello Merlino

  97. Approximate Values for Force Constant and Wave Number Associated with a Low-Frequency Concerted Motion in Proteins Can Be Evaluated by a Comparison of X-ray Structures

    Article • The Journal of Physical Chemistry B, April 2007, American Chemical Society (ACS)

    Professor Antonello Merlino

  98. High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect

    Article • Proteins Structure Function and Bioinformatics, August 2006, Wiley

    Alessandro Vergara, Professor Antonello Merlino

  99. Polyglutamine repeats and β‐helix structure: Molecular dynamics study

    Article • Proteins Structure Function and Bioinformatics, March 2006, Wiley

    Professor Antonello Merlino

  100. Minimal structural requirements for root effect: Crystal structure of the cathodic hemoglobin isolated from the antarctic fish Trematomus newnesi

    Article • Proteins Structure Function and Bioinformatics, November 2005, Wiley

    Alessandro Vergara, Professor Antonello Merlino

  101. The Importance of Dynamic Effects on the Enzyme Activity

    Article • Journal of Biological Chemistry, May 2005, Elsevier

    Professor Antonello Merlino

  102. Open Interface and Large Quaternary Structure Movements in 3D Domain Swapped Proteins: Insights from Molecular Dynamics Simulations of the C-Terminal Swapped Dimer of Ribonuclease A

    Article • Biophysical Journal, March 2005, Elsevier

    Professor Antonello Merlino

  103. S-adenosylhomocysteine hydrolase from the archaeon Pyrococcus furiosus: Biochemical characterization and analysis of protein structure by comparative molecular modeling

    Article • Proteins Structure Function and Bioinformatics, January 2005, Wiley

    Professor Antonello Merlino

  104. Structural and dynamic effects of α‐Helix deletion in Sso7d: Implications for protein thermal stability

    Article • Proteins Structure Function and Bioinformatics, August 2004, Wiley

    Professor Antonello Merlino

  105. Structure and Stability of the Non-covalent Swapped Dimer of Bovine Seminal Ribonuclease

    Article • Journal of Biological Chemistry, August 2004, Elsevier

    Professor Antonello Merlino

  106. Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer

    Article • Biopolymers, February 2004, Wiley

    Associate professor Filomena Sica, Professor Antonello Merlino

  107. Subtle functional collective motions in pancreatic‐like ribonucleases: From ribonuclease A to angiogenin

    Article • Proteins Structure Function and Bioinformatics, August 2003, Wiley

    Professor Antonello Merlino

  108. Global and local motions in ribonuclease A: A molecular dynamics study

    Article • Biopolymers, September 2002, Wiley

    Professor Antonello Merlino

  109. Reversible substrate‐induced domain motions in ribonuclease A

    Article • Proteins Structure Function and Bioinformatics, November 2001, Wiley

    Professor Antonello Merlino

  110. A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease 1 1Edited by A. R. Fersht

    Article • Journal of Molecular Biology, October 1999, Elsevier

    Associate professor Filomena Sica, Professor Antonello Merlino