All Stories

  1. Esomeprazole Decreases Soluble Fms-like Tyrosine Kinase-1 in Preeclamptic Pregnancy in Rats

    Article • International Journal of Molecular Sciences, March 2026, MDPI AG

    Professor Marcos R M Fontes

  2. Structural and Pharmacological Analysis of a PLA2-like Toxin in Complex with the sPLA2 Inhibitor AZD2716: Comparisons to Varespladib

    Article • Biochimie, March 2026, Elsevier

    Professor Marcos R M Fontes

  3. Production of two novel antifungal peroxidase isoenzymes from Tabernaemontana catharinensis using a bubble-column bioreactor

    Article • Phytochemistry, July 2025, Elsevier

    Professor Marcos R M Fontes

  4. Guttiferone E from Brazilian red propolis inhibited wound-isolated methicillin-resistant Staphylococcus aureus and enhanced the bactericidal action of suppressed macrophages

    Article • Phytomedicine, May 2025, Elsevier

    Professor Marcos R M Fontes

  5. Transport of DNA repair proteins to the cell nucleus by the classical nuclear importin pathway – a structural overview

    Article • DNA Repair, May 2025, Elsevier

    Professor Marcos R M Fontes

  6. Exploring the structure and nucleic acid interactions of the Leishmania sp. telomerase reverse transcriptase N-terminal region

    Article • Archives of Biochemistry and Biophysics, February 2025, Elsevier

    Professor Marcos R M Fontes

  7. Molecular interaction assays in silico of crotapotin from Crotalus durissus terrificus against the molecular target trypanothione reductase from Leishmania braziliensis

    Article • Journal of Venomous Animals and Toxins including Tropical Diseases, January 2025, FapUNIFESP (SciELO)

    Professor Marcos R M Fontes

  8. The two crystal structures of unloaded and cargo-loaded Vacuolar Sorting Receptor 1 lumenal domain (VSR1-Nt) reveal two cargo binding sites and a mechanism of transport

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Professor Marcos R M Fontes

  9. Inhibitors and activators for myotoxic phospholipase A2-like toxins from snake venoms – A structural overview

    Article • Biochimie, December 2024, Elsevier

    Professor Marcos R M Fontes

  10. Potential Biotechnological Applications of Venoms from the Viperidae Family in Central America for Thrombosis

    Article • Toxins, March 2024, MDPI AG

    Professor Marcos R M Fontes

  11. Structural studies with crotoxin B from Crotalus durissus collilineatus venom suggest a heterodimeric assembly formed by two new isoforms

    Article • Biochimie, March 2024, Elsevier

    Professor Marcos R M Fontes

  12. BthTX-I, a phospholipase A2-like toxin, is inhibited by the plant cinnamic acid derivative: chlorogenic acid

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, February 2024, Elsevier

    Professor Marcos R M Fontes

  13. Structural basis of nuclear transport for NEIL DNA glycosylases mediated by importin-alpha

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, February 2024, Elsevier

    Professor Marcos R M Fontes

  14. Biochemical and structural characterization of the RT domain of Leishmania sp. telomerase reverse transcriptase

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, November 2023, Elsevier

    Professor Marcos R M Fontes

  15. Mapping possible interaction sites for crotoxin in CNF, a gamma PLA2 inhibitor from Crotalus durissus terrificus rattle snake, using SPOT synthesis

    Article • Toxicon, October 2023, Elsevier

    Professor Marcos R M Fontes

  16. Interactions of the male contraceptive target EPPIN with semenogelin-1 and small organic ligands

    Article • Scientific Reports, September 2023, Springer Science + Business Media

    Professor Marcos R M Fontes

  17. A C-type lectin induces NLRP3 inflammasome activation via TLR4 interaction in human peripheral blood mononuclear cells

    Article • Cellular and Molecular Life Sciences, June 2023, Springer Science + Business Media

    Professor Marcos R M Fontes

  18. Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib

    Article • Biochimie, April 2023, Elsevier

    Professor Marcos R M Fontes

  19. Structural and functional studies of a snake venom phospholipase A2-like protein complexed to an inhibitor from Tabernaemontana catharinensis

    Article • Biochimie, March 2023, Elsevier

    Professor Marcos R M Fontes

  20. Anti-Metalloprotease P-I Single-Domain Antibodies: Tools for Next-Generation Snakebite Antivenoms

    Article • BioMed Research International, July 2022, Hindawi Publishing Corporation

    Professor Marcos R M Fontes

  21. SEQUENCE SLIDER: integration of structural and genetic data to characterize isoforms from natural sources

    Article • Nucleic Acids Research, February 2022, Oxford University Press (OUP)

    Professor Marcos R M Fontes

  22. Correlating biological activity to thermo-structural analysis of the interaction of CTX with synthetic models of macrophage membranes

    Article • Scientific Reports, December 2021, Springer Science + Business Media

    Professor Marcos R M Fontes

  23. BthTX-II from Bothrops jararacussu venom has variants with different oligomeric assemblies: An example of snake venom phospholipases A2 versatility

    Article • International Journal of Biological Macromolecules, November 2021, Elsevier

    Professor Marcos R M Fontes

  24. Towards toxin PEGylation: The example of rCollinein-1, a snake venom thrombin-like enzyme, as a PEGylated biopharmaceutical prototype

    Article • International Journal of Biological Macromolecules, November 2021, Elsevier

    Professor Marcos R M Fontes

  25. SEQUENCE SLIDER: integration of structural and genetic data to characterize isoforms from natural source

    Article • September 2021, Cold Spring Harbor Laboratory Press

    Professor Marcos R M Fontes

  26. Corona Protein Impacts on Alternating Current Biosusceptometry Signal and Circulation Times of Differently Coated Mnfe 2 O 4 Nanoparticles

    Article • Nanomedicine, September 2021, Taylor & Francis

    Professor Marcos R M Fontes

  27. Mitochondrial sirtuin TcSir2rp3 affects TcSODA activity and oxidative stress response in Trypanosoma cruzi

    Article • September 2021, Cold Spring Harbor Laboratory Press

    Professor Marcos R M Fontes

  28. Gallic acid anti-myotoxic activity and mechanism of action, a snake venom phospholipase A2 toxin inhibitor, isolated from the medicinal plant Anacardium humile

    Article • International Journal of Biological Macromolecules, August 2021, Elsevier

    Professor Marcos R M Fontes

  29. Structural and calorimetric studies reveal specific determinants for the binding of a high-affinity NLS to mammalian importin-alpha

    Article • Biochemical Journal, July 2021, Portland Press Ltd.

    Professor Marcos R M Fontes

  30. The synthetic varespladib molecule is a multi-functional inhibitor for PLA2 and PLA2-like ophidic toxins

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, July 2021, Elsevier

    Professor Marcos R M Fontes

  31. In-solution structural studies involving a phospholipase A2-like myotoxin and a natural inhibitor: Plasticity of oligomeric assembly affects mechanisms of inhibition

    Article • Biochimie, February 2021, Elsevier

    Professor Marcos R M Fontes

  32. Biochemical, pharmacological and structural characterization of BmooMP-I, a new P–I metalloproteinase from Bothrops moojeni venom

    Article • Biochimie, December 2020, Elsevier

    Professor Marcos R M Fontes

  33. Beyond hemostasis: a snake venom serine protease with potassium channel blocking and potential antitumor activities

    Article • Scientific Reports, March 2020, Springer Science + Business Media

    Professor Marcos R M Fontes

  34. Neutralization of a bothropic PLA2-like protein by caftaric acid, a novel potent inhibitor of ophidian myotoxicity

    Article • Biochimie, March 2020, Elsevier

    Professor Marcos R M Fontes

  35. SEQUENCE SLIDER: expanding polyalanine fragments for phasing with multiple side-chain hypotheses

    Article • Acta Crystallographica Section D Structural Biology, February 2020, International Union of Crystallography

    Dr. Rafael Junqueira Borges, Dr Massimo Domenico Sammito, Claudia Millán, Professor Marcos R M Fontes

  36. Comparative study of the interactions between fungal transcription factor nuclear localization sequences with mammalian and fungal importin-alpha

    Article • Scientific Reports, January 2020, Springer Science + Business Media

    Professor Marcos R M Fontes

  37. Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920)

    Article • Scientific Reports, November 2019, Springer Science + Business Media

    Professor Marcos R M Fontes

  38. Identification, description and structural analysis of beta phospholipase A2 inhibitors (sbβPLIs) from Latin American pit vipers indicate a binding site region for basic snake venom phospholipases A2

    Article • Toxicon X, April 2019, Elsevier

    Professor Marcos R M Fontes

  39. Search for efficient inhibitors of myotoxic activity induced by ophidian phospholipase A2-like proteins using functional, structural and bioinformatics approaches

    Article • Scientific Reports, January 2019, Springer Science + Business Media

    Professor Marcos R M Fontes

  40. Structural basis of phospholipase A2-like myotoxin inhibition by chicoric acid, a novel potent inhibitor of ophidian toxins

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, December 2018, Elsevier

    Professor Marcos R M Fontes

  41. Identification of a putative nuclear localization signal in maspin protein shed light into its nuclear import regulation

    Article • November 2018, Cold Spring Harbor Laboratory Press

    Professor Marcos R M Fontes

  42. In Vivo genotoxicity of a commercial C.I. Disperse Red 1 dye

    Article • Environmental and Molecular Mutagenesis, August 2018, Wiley

    Anjaina Fernandes de Albuquerque, Professor Marcos R M Fontes

  43. Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism

    Article • Scientific Reports, July 2018, Springer Science + Business Media

    Professor Marcos R M Fontes

  44. DNA mismatch repair proteins MLH1 and PMS2 can be imported to the nucleus by a classical nuclear import pathway

    Article • Biochimie, March 2018, Elsevier

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  45. Structural evidence for a fatty acid-independent myotoxic mechanism for a phospholipase A2-like toxin

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, March 2018, Elsevier

    Professor Marcos R M Fontes

  46. Secreted Phospholipases A2 from Animal Venoms in Pain and Analgesia

    Article • Toxins, December 2017, MDPI AG

    Professor Marcos R M Fontes

  47. Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by importin-α

    Article • Biochemical Journal, December 2017, Portland Press Ltd.

    Professor Marcos R M Fontes

  48. PLA2-like proteins myotoxic mechanism: a dynamic model description

    Article • Scientific Reports, November 2017, Springer Science + Business Media

    Professor Marcos R M Fontes

  49. Replication Protein A‐1 Has a Preference for the Telomeric G‐rich Sequence in Trypanosoma cruzi

    Article • Journal of Eukaryotic Microbiology, November 2017, Wiley

    Professor Marcos R M Fontes

  50. Neuromuscular paralysis by the basic phospholipase A 2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently inhibit acetylcholine release and produce muscle blockage

    Article • Toxicology and Applied Pharmacology, November 2017, Elsevier

    MD, PhD Paulo Correia-de-Sá, Professor Marcos R M Fontes

  51. Structural studies with BnSP-7 reveal an atypical oligomeric conformation compared to phospholipases A2-like toxins

    Article • Biochimie, November 2017, Elsevier

    Professor Marcos R M Fontes

  52. A calmodulin-like protein (LCALA) is a new Leishmania amazonensis candidate for telomere end-binding protein

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, November 2017, Elsevier

    Professor Marcos R M Fontes

  53. Molecular cloning and structural modelling of gamma-phospholipase A2 inhibitors from Bothrops atrox and Micrurus lemniscatus snakes

    Article • International Journal of Biological Macromolecules, October 2017, Elsevier

    Professor Marcos R M Fontes

  54. BmajPLA 2 -II, a basic Lys49-phospholipase A 2 homologue from Bothrops marajoensis snake venom with parasiticidal potential

    Article • International Journal of Biological Macromolecules, September 2017, Elsevier

    Professor Marcos R M Fontes

  55. Biophysical studies suggest a new structural arrangement of crotoxin and provide insights into its toxic mechanism

    Article • Scientific Reports, March 2017, Springer Science + Business Media

    Professor Marcos R M Fontes

  56. Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative “myotoxic cluster”

    Article • Biochimie, February 2017, Elsevier

    Professor Marcos R M Fontes

  57. Functional and structural studies of a Phospholipase A2-like protein complexed to zinc ions: Insights on its myotoxicity and inhibition mechanism

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, January 2017, Elsevier

    Professor Marcos R M Fontes

  58. Replication Protein A Presents Canonical Functions and Is Also Involved in the Differentiation Capacity of Trypanosoma cruzi

    Article • PLoS Neglected Tropical Diseases, December 2016, PLOS

    Professor Marcos R M Fontes

  59. Structural and thermodynamic studies of the tobacco calmodulin-like rgs-CaM protein

    Article • International Journal of Biological Macromolecules, November 2016, Elsevier

    Professor Marcos R M Fontes

  60. Molecular Components of the Neurospora crassa pH Signaling Pathway and Their Regulation by pH and the PAC-3 Transcription Factor

    Article • PLOS One, August 2016, PLOS

    Professor Marcos R M Fontes

  61. Structural and Calorimetric Studies Demonstrate that Xeroderma Pigmentosum Type G (XPG) Can Be Imported to the Nucleus by a Classical Nuclear Import Pathway via a Monopartite NLS Sequence

    Article • Journal of Molecular Biology, May 2016, Elsevier

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  62. Structural and evolutionary insights into endogenous alpha-phospholipase A 2 inhibitors of Latin American pit vipers

    Article • Toxicon, March 2016, Elsevier

    Professor Marcos R M Fontes

  63. A novel synthetic quinolinone inhibitor presents proteolytic and hemorrhagic inhibitory activities against snake venom metalloproteases

    Article • Biochimie, February 2016, Elsevier

    Professor Marcos R M Fontes

  64. Phospholipase A2 Inhibitors from Snake Blood (sbPLIs)

    Article • January 2016, Springer Science + Business Media

    Professor Marcos R M Fontes

  65. Structural Biology and Regulation of Protein Import into the Nucleus

    Article • Journal of Molecular Biology, October 2015, Elsevier

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  66. Structural and functional evidence for membrane docking and disruption sites on phospholipase A2-like proteins revealed by complexation with the inhibitor suramin

    Article • Acta Crystallographica Section D Biological Crystallography, September 2015, International Union of Crystallography

    Professor Marcos R M Fontes

  67. Transcriptionally active LTR retrotransposons in Eucalyptus genus are differentially expressed and insertionally polymorphic

    Article • BMC Plant Biology, August 2015, Springer Science + Business Media

    Professor Marcos R M Fontes

  68. Structural Basis for the Inhibition of a Phospholipase A2-Like Toxin by Caffeic and Aristolochic Acids

    Article • PLOS One, July 2015, PLOS

    Professor Marcos R M Fontes

  69. Structure of Importin-α from a Filamentous Fungus in Complex with a Classical Nuclear Localization Signal

    Article • PLOS One, June 2015, PLOS

    Professor Marcos R M Fontes

  70. Quantitative Decomposition of Dynamics of Mathematical Cell Models: Method and Application to Ventricular Myocyte Models

    Article • PLOS One, June 2015, PLOS

    Professor Marcos R M Fontes

  71. A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, December 2014, Elsevier

    Professor Marcos R M Fontes

  72. RPA‐1 from Leishmania amazonensis (LaRPA‐1) structurally differs from other eukaryote RPA‐1 and interacts with telomeric DNA via its N‐terminal OB‐fold domain

    Article • FEBS Letters, November 2014, Wiley

    Professor Marcos R M Fontes

  73. Insights on the structure of native CNF, an endogenous phospholipase A2 inhibitor from Crotalus durissus terrificus, the South American rattlesnake

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, September 2014, Elsevier

    Professor Marcos R M Fontes

  74. Isolation and biochemical characterization of a γ-type phospholipase A2 inhibitor from Crotalus durissus collilineatus snake serum

    Article • Toxicon, April 2014, Elsevier

    Professor Marcos R M Fontes

  75. Crystallization and preliminary X-ray crystallographic analysis of importin-α fromNeurospora crassa

    Article • Acta Crystallographica Section F Structural Biology Communications, March 2014, International Union of Crystallography

    Professor Marcos R M Fontes

  76. Alkylation of Histidine Residues ofBothrops jararacussuVenom Proteins and Isolated PhospholipasesA2

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Marcos R M Fontes

  77. An Evaluation of 3-Rhamnosylquercetin, a Glycosylated Form of Quercetin, against the Myotoxic and Edematogenic Effects of sPLA2fromCrotalus durissus terrificus

    Article • BioMed Research International, January 2014, Hindawi Publishing Corporation

    Professor Marcos R M Fontes

  78. Biochemical, functional, structural and phylogenetic studies on Intercro, a new isoform phospholipase A2 from Crotalus durissus terrificus snake venom

    Article • Biochimie, December 2013, Elsevier

    Professor Marcos R M Fontes

  79. Structural bases for a complete myotoxic mechanism: Crystal structures of two non-catalytic phospholipases A2-like from Bothrops brazili venom

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, December 2013, Elsevier

    Professor Marcos R M Fontes

  80. Structural and functional studies with mytoxin II from Bothrops moojeni reveal remarkable similarities and differences compared to other catalytically inactive phospholipases A2-like

    Article • Toxicon, September 2013, Elsevier

    Professor Marcos R M Fontes

  81. Structural and Phylogenetic Studies with MjTX-I Reveal a Multi-Oligomeric Toxin – a Novel Feature in Lys49-PLA2s Protein Class

    Article • PLOS One, April 2013, PLOS

    Professor Marcos R M Fontes

  82. Phylogenetic and structural studies of a novel equine papillomavirus identified from aural plaques

    Article • Veterinary Microbiology, February 2013, Elsevier

    Professor Marcos R M Fontes

  83. Triacontyl p-coumarate: An inhibitor of snake venom metalloproteinases

    Article • Phytochemistry, February 2013, Elsevier

    Professor Marcos R M Fontes

  84. Crystallization and preliminary X-ray diffraction analysis of three myotoxic phospholipases A2fromBothrops brazilivenom

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2012, International Union of Crystallography

    Professor Marcos R M Fontes

  85. Structural basis of nuclear import of flap endonuclease 1 (FEN1)

    Article • Acta Crystallographica Section D Biological Crystallography, June 2012, International Union of Crystallography

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  86. Structural and Functional Studies of a Bothropic Myotoxin Complexed to Rosmarinic Acid: New Insights into Lys49-PLA2 Inhibition

    Article • PLOS One, December 2011, PLOS

    Professor Marcos R M Fontes

  87. Structural Basis of Importin-α-Mediated Nuclear Transport for Ku70 and Ku80

    Article • Journal of Molecular Biology, September 2011, Elsevier

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  88. Crystallization and preliminary X-ray diffraction studies of BmooPLA2-I, a platelet-aggregation inhibitor and hypotensive phospholipase A2fromBothrops moojenivenom

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2011, International Union of Crystallography

    Professor Marcos R M Fontes

  89. Molecular cloning and biochemical characterization of a myotoxin inhibitor from Bothrops alternatus snake plasma

    Article • Biochimie, March 2011, Elsevier

    Professor Marcos R M Fontes

  90. Crystallization and preliminary X-ray diffraction analysis of a Lys49-phospholipase A2complexed with caffeic acid, a molecule with inhibitory properties against snake venoms

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, January 2011, International Union of Crystallography

    Professor Marcos R M Fontes

  91. Structural, functional, and bioinformatics studies reveal a new snake venom homologue phospholipase A2 class

    Article • Proteins Structure Function and Bioinformatics, September 2010, Wiley

    Professor Marcos R M Fontes

  92. In vivo uptake of a haem analogue Zn protoporphyrin IX by the human malaria parasite P. falciparum‐infected red blood cells

    Article • Cell Biology International, August 2010, Wiley

    Professor Marcos R M Fontes

  93. Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca2+-binding loop region for the catalytically inactive Lys49-PLA2s

    Article • Journal of Structural Biology, July 2010, Elsevier

    Professor Marcos R M Fontes

  94. Crotoxin: Novel activities for a classic β-neurotoxin

    Article • Toxicon, June 2010, Elsevier

    Professor Marcos R M Fontes

  95. Crystallization and preliminary X-ray crystallographic studies of a Lys49-phospholipase A2homologue fromBothrops pirajaivenom complexed with rosmarinic acid

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, May 2010, International Union of Crystallography

    Professor Marcos R M Fontes

  96. Probing the Specificity of Binding to the Major Nuclear Localization Sequence-binding Site of Importin-  Using Oriented Peptide Library Screening

    Article • Journal of Biological Chemistry, April 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  97. Crystal structure of a phospholipase A2 homolog complexed with p-bromophenacyl bromide reveals important structural changes associated with the inhibition of myotoxic activity

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, November 2009, Elsevier

    Professor Marcos R M Fontes

  98. Identification of continuous interaction sites in PLA2-based protein complexes by peptide arrays

    Article • Biochimie, November 2009, Elsevier

    Professor Marcos R M Fontes

  99. Crystallization and preliminary X-ray diffraction analysis of crotoxin B fromCrotalus durissus collilineatusvenom

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, September 2009, International Union of Crystallography

    Professor Marcos R M Fontes

  100. Editorial [Hot Topic: Structural-Functional Studies of Animal Toxins (Guest Editor: Marcos R.M. Fontes)]

    Article • Protein and Peptide Letters, August 2009, Bentham Science Publishers

    Professor Marcos R M Fontes

  101. Influence of Quaternary Conformation on the Biological Activities of the Asp49-phospholipases A2s from Snake Venoms

    Article • Protein and Peptide Letters, August 2009, Bentham Science Publishers

    Professor Marcos R M Fontes

  102. The Intriguing Phospholipases A2 Homologues: Relevant Structural Features on Myotoxicity and Catalytic Inactivity

    Article • Protein and Peptide Letters, August 2009, Bentham Science Publishers

    Professor Marcos R M Fontes

  103. Comparative structural studies on Lys49-phospholipases A2 from Bothrops genus reveal their myotoxic site

    Article • Journal of Structural Biology, August 2009, Elsevier

    Professor Marcos R M Fontes

  104. Structural and functional properties of Bp-LAAO, a new l-amino acid oxidase isolated from Bothrops pauloensis snake venom

    Article • Biochimie, April 2009, Elsevier

    Flavio Henrique-Silva, Professor Marcos R M Fontes

  105. Crystal structure of a myotoxic Asp49-phospholipase A2 with low catalytic activity: Insights into Ca2+-independent catalytic mechanism

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, April 2008, Elsevier

    Professor Marcos R M Fontes

  106. Molecular characterization of BjussuSP-I, a new thrombin-like enzyme with procoagulant and kallikrein-like activity isolated from Bothrops jararacussu snake venom

    Article • Biochimie, March 2008, Elsevier

    Professor Marcos R M Fontes

  107. Insights into the role of oligomeric state on the biological activities of crotoxin: Crystal structure of a tetrameric phospholipase A2formed by two isoforms of crotoxin B fromCrotalus durissus terrificusvenom

    Article • Proteins Structure Function and Bioinformatics, February 2008, Wiley

    Professor Marcos R M Fontes

  108. Molecular and functional characterization of a new non-hemorrhagic metalloprotease from Bothrops jararacussu snake venom with antiplatelet activity

    Article • Peptides, December 2007, Elsevier

    Professor Marcos R M Fontes

  109. Preliminary X-ray crystallographic studies of a tetrameric phospholipase A2formed by two isoforms of crotoxin B fromCrotalus durissus terrificusvenom

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, November 2007, International Union of Crystallography

    Professor Marcos R M Fontes

  110. Preliminary X-Ray Crystallographic Studies of a Lys49-Phospholipase A2 Homologue from Bothrops pirajai Venom Complexed with p-Bromophenacyl Bromide and α-Tocopherol Inhibitors

    Article • Protein and Peptide Letters, July 2007, Bentham Science Publishers

    Professor Marcos R M Fontes

  111. Molecular characterization and phylogenetic analysis of BjussuMP-I: A RGD-P-III class hemorrhagic metalloprotease from Bothrops jararacussu snake venom

    Article • Journal of Molecular Graphics and Modelling, July 2007, Elsevier

    Professor Marcos R M Fontes

  112. Snake Venom Phospholipase A2 Inhibitors: Medicinal Chemistry and Therapeutic Potential

    Article • Current Topics in Medicinal Chemistry, April 2007, Bentham Science Publishers

    Professor Marcos R M Fontes

  113. Molecular approaches for structural characterization of Bothropsl-amino acid oxidases with antiprotozoal activity: cDNA cloning, comparative sequence analysis, and molecular modeling

    Article • Biochemical and Biophysical Research Communications, April 2007, Elsevier

    Professor Marcos R M Fontes

  114. Preliminary X-ray crystallographic studies of BthTX-II, a myotoxic Asp49-phospholipase A2with low catalytic activity fromBothrops jararacussuvenom

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, July 2006, International Union of Crystallography

    Professor Marcos R M Fontes

  115. Crystallization and preliminary X-ray diffraction analysis of a myotoxic Lys49-PLA2fromBothrops jararacussuvenom complexed withp-bromophenacyl bromide

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, May 2006, International Union of Crystallography

    Professor Marcos R M Fontes

  116. Bothrops moojeni myotoxin-II, a Lys49-phospholipase A2 homologue: An example of function versatility of snake venom proteins

    Article • Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, March 2006, Elsevier

    Professor Marcos R M Fontes

  117. Structure of BthA-I complexed withp-bromophenacyl bromide: possible correlations with lack of pharmacological activity

    Article • Acta Crystallographica Section D Biological Crystallography, November 2005, International Union of Crystallography

    Professor Marcos R M Fontes

  118. Crystallization and Preliminary X-Ray Diffraction Studies of Two Myotoxic Lys49-Phospholipases A2 Complexed with α-Tocopherol

    Article • Protein and Peptide Letters, November 2005, Bentham Science Publishers

    Professor Marcos R M Fontes

  119. Crystallization and preliminary X-ray diffraction analysis of myotoxin I, a Lys49-phospholipase A2fromBothrops moojeni

    Article • Acta Crystallographica Section F Structural Biology and Crystallization Communications, September 2005, International Union of Crystallography

    Professor Marcos R M Fontes

  120. Rosmarinic acid, a new snake venom phospholipase A2 inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction

    Article • Toxicon, September 2005, Elsevier

    Professor Marcos R M Fontes

  121. Crystallization and preliminary X-ray diffraction analysis of importin-α complexed with NLS peptidomimetics

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, June 2005, Elsevier

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  122. Structural insights for fatty acid binding in a Lys49-phospholipase A2: crystal structure of myotoxin II from Bothrops moojeni complexed with stearic acid

    Article • Biochimie, February 2005, Elsevier

    Professor Raghuvir K Arni, Professor Marcos R M Fontes

  123. Phospholipase A2 Myotoxins from Bothrops Snake Venoms: Structure- Function Relationship

    Article • Current Organic Chemistry, November 2004, Bentham Science Publishers

    Professor Marcos R M Fontes

  124. Crystal structure of an acidic platelet aggregation inhibitor and hypotensive phospholipase A2 in the monomeric and dimeric states: insights into its oligomeric state

    Article • Biochemical and Biophysical Research Communications, October 2004, Elsevier

    Professor Raghuvir K Arni, Professor Marcos R M Fontes

  125. Crystallization and preliminary X-ray diffraction analysis of an acidic phospholipase A2 complexed with p-bromophenacyl bromide and α-tocopherol inhibitors at 1.9- and 1.45-Å resolution

    Article • Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, June 2004, Elsevier

    Professor Marcos R M Fontes

  126. Cloning and Identification of a Complete cDNA Coding for a Bactericidal and Antitumoral Acidic Phospholipase A2 from Bothrops jararacussu Venom

    Article • The Protein Journal, May 2004, Springer Science + Business Media

    Professor Marcos R M Fontes

  127. Analysis of Bothrops jararacussu venomous gland transcriptome focusing on structural and functional aspects11All sequence data reported in this paper will appear in the GenBank database under the following accession numbers: BOJU-I (AY 185200), BOJU-II...

    Article • Biochimie, March 2004, Elsevier

    Professor Marcos R M Fontes

  128. Crystal structures of BnSP-7 and BnSP-6, two Lys49-phospholipases A2: quaternary structure and inhibition mechanism insights

    Article • Biochemical and Biophysical Research Communications, November 2003, Elsevier

    Professor Marcos R M Fontes

  129. Role of flanking sequences and phosphorylation in the recognition of the simian-virus-40 large T-antigen nuclear localization sequences by importin-α

    Article • Biochemical Journal, October 2003, Portland Press Ltd.

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  130. Initiating Structural Studies Of Lys49-Pla2 Homologues Complexed With An Anionic Detergent, A Fatty Acid And A Natural Lipid

    Article • Protein and Peptide Letters, October 2003, Bentham Science Publishers

    Professor Marcos R M Fontes

  131. Structural Basis for the Specificity of Bipartite Nuclear Localization Sequence Binding by Importin- 

    Article • Journal of Biological Chemistry, April 2003, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  132. The Structure of HLA-B8 Complexed to an Immunodominant Viral Determinant: Peptide-Induced Conformational Changes and a Mode of MHC Class I Dimerization

    Article • The Journal of Immunology, November 2002, The American Association of Immunologists

    Professor Anthony W Purcell, Professor Marcos R M Fontes

  133. Structural and functional characterization of an acidic platelet aggregation inhibitor and hypotensive phospholipase A2 from Bothrops jararacussu snake venom

    Article • Biochemical Pharmacology, August 2002, Elsevier

    Professor Marcos R M Fontes

  134. cDNA sequence and molecular modeling of a nerve growth factor from Bothrops jararacussu venomous gland

    Article • Biochimie, July 2002, Elsevier

    Professor Marcos R M Fontes

  135. Biophysical Characterization of Interactions Involving Importin-  during Nuclear Import

    Article • Journal of Biological Chemistry, July 2001, American Society for Biochemistry & Molecular Biology (ASBMB)

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  136. Comparative Biochemical Studies of Myotoxic Phospholipase A2 From Bothrops Venom

    Article • Protein and Peptide Letters, June 2001, Bentham Science Publishers

    Professor Marcos R M Fontes

  137. Crystallization and preliminary X-ray diffraction studies of FHA domains of Dun1 and Rad53 protein kinases

    Article • Acta Crystallographica Section D Biological Crystallography, March 2001, International Union of Crystallography

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  138. Structural and Functional Characterization of Neuwiedase, a Nonhemorrhagic Fibrin(ogen)olytic Metalloprotease from Bothrops neuwiedi Snake Venom

    Article • Archives of Biochemistry and Biophysics, September 2000, Elsevier

    Professor Marcos R M Fontes

  139. Structural and Functional Characterization of BnSP-7, a Lys49 Myotoxic Phospholipase A2 Homologue from Bothrops neuwiedi pauloensis Venom

    Article • Archives of Biochemistry and Biophysics, June 2000, Elsevier

    Professor Marcos R M Fontes

  140. Structural basis of recognition of monopartite and bipartite nuclear localization sequences by mammalian importin-α11Edited by K. Nagai

    Article • Journal of Molecular Biology, April 2000, Elsevier

    Professor Bostjan Kobe, Professor Marcos R M Fontes

  141. Crystallization and preliminary X-ray diffraction analysis of a myotoxic phospholipase A2 homologue from Bothrops neuwiedi pauloensis venom

    Article • Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, July 1999, Elsevier

    Professor Marcos R M Fontes

  142. Crystal Structure of Myotoxin II, a Monomeric Lys49-Phospholipase A2 Homologue Isolated from the Venom of Cerrophidion (Bothrops) godmani

    Article • Archives of Biochemistry and Biophysics, June 1999, Elsevier

    Professor Marcos R M Fontes

  143. Geographic variations in the composition of myotoxins from Bothrops neuwiedi snake venoms: biochemical characterization and biological activity

    Article • Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology, November 1998, Elsevier

    Professor Marcos R M Fontes

  144. Synthesis, characterization and molecular structures of the pyridinium trans-Bis(pyridine)tetrachlororuthenate(III) and pyridinium trans-(carbonyl)(pyridine)tetrachlororuthenate(III)

    Article • Journal of the Brazilian Chemical Society, January 1997, FapUNIFESP (SciELO)

    Professor Marcos R M Fontes

  145. RuCl2(CO)2(N-methylimidazole)2Isomers: Synthesis, Characterization and Reactivity

    Article • Journal of the Brazilian Chemical Society, January 1996, Sociedade Brasileira de Quimica (SBQ)

    Professor Marcos R M Fontes

  146. Structure and catalytic mechanism of glucosamine 6-phosphate deaminase from Escherichia coli at 2.1 å resolution

    Article • Structure, December 1995, Elsevier

    Professor Marcos R M Fontes

  147. NOTE: THE CRYSTAL AND MOLECULAR STRUCTURE OF BIS[1,3-BIS(DIPHENYLPHOSPHINO) PROPANE] DICHLORORUTHENIUM (II)

    Article • Journal of Coordination Chemistry, October 1993, Taylor & Francis

    Professor Marcos R M Fontes

  148. Structure of 1,4-bis(diphenylphosphinoyl)butane

    Article • Acta Crystallographica Section C Crystal Structure Communications, December 1991, International Union of Crystallography

    Professor Marcos R M Fontes