All Stories

  1. Transcriptomes and shRNA Suppressors in a TP53 Allele–Specific Model of Early-Onset Colon Cancer in African Americans

    Article • Molecular Cancer Research, July 2014, American Association for Cancer Research (AACR)

    Marc Birtwistle

  2. Evaluating Strategies to Normalise Biological Replicates of Western Blot Data

    Article • PLoS ONE, January 2014, PLOS

    Marc Birtwistle, Professor Boris N. Kholodenko

  3. Dimerization-based control of cooperativity

    Article • Molecular BioSystems, January 2014, Royal Society of Chemistry

    Mehdi Bouhaddou, Marc Birtwistle

  4. A General Network Pharmacodynamic Model–Based Design Pipeline for Customized Cancer Therapy Applied to the VEGFR Pathway

    Article • CPT Pharmacometrics & Systems Pharmacology, January 2014, Wiley

    Marc Birtwistle

  5. Extracellular Signal-Regulated Kinase Regulates RhoA Activation and Tumor Cell Plasticity by Inhibiting Guanine Exchange Factor H1 Activity

    Article • Molecular and Cellular Biology, September 2013, ASM Journals

    Marc Birtwistle

  6. Mechanistic Vs. Empirical Network Models of Drug Action

    Article • CPT Pharmacometrics & Systems Pharmacology, September 2013, Wiley

    Marc Birtwistle

  7. A Comparison of Methods for RNA-Seq Differential Expression Analysis and a New Empirical Bayes Approach

    Article • Biosensors, June 2013, MDPI AG

    Marc Birtwistle

  8. Bayesian multivariate Poisson abundance models for T-cell receptor data

    Article • Journal of Theoretical Biology, June 2013, Elsevier

    Marc Birtwistle

  9. Emergence of bimodal cell population responses from the interplay between analog single-cell signaling and protein expression noise

    Article • BMC Systems Biology, August 2012, Springer Science + Business Media

    Marc Birtwistle, Dr Maciej Dobrzynski, Professor Boris N. Kholodenko

  10. Novel Somatic Mutations to PI3K Pathway Genes in Metastatic Melanoma

    Article • PLoS ONE, August 2012, PLOS

    Marc Birtwistle

  11. ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin- 2

    Article • Journal of Cell Science, February 2012, The Company of Biologists

    Marc Birtwistle

  12. Mammalian protein expression noise: scaling principles and the implications for knockdown experiments

    Article • Molecular BioSystems, January 2012, Royal Society of Chemistry

    Marc Birtwistle, Dr Maciej Dobrzynski, Professor Boris N. Kholodenko

  13. Linear Approaches to Intramolecular Förster Resonance Energy Transfer Probe Measurements for Quantitative Modeling

    Article • PLoS ONE, November 2011, PLOS

    Marc Birtwistle

  14. NFκB and HIF display synergistic behaviour during hypoxic inflammation

    Article • Cellular and Molecular Life Sciences, November 2011, Springer Science + Business Media

    Marc Birtwistle

  15. Biology using engineering tools

    Article • Cell Cycle, July 2011, Taylor & Francis

    Marc Birtwistle

  16. Raf Family Kinases: Old Dogs Have Learned New Tricks

    Article • Genes & Cancer, March 2011, SAGE Publications

    Marc Birtwistle, Dr David Matallanas

  17. Ligand-Specific c-Fos Expression Emerges from the Spatiotemporal Control of ErbB Network Dynamics

    Article • Cell, May 2010, Elsevier

    Marc Birtwistle, Professor Boris N. Kholodenko

  18. Cell fate decisions are specified by the dynamic ERK interactome

    Article • Nature Cell Biology, November 2009, Springer Science + Business Media

    Marc Birtwistle

  19. Endocytosis and signalling: A meeting with mathematics

    Article • Molecular Oncology, June 2009, Wiley

    Marc Birtwistle, Professor Boris N. Kholodenko

  20. Four‐dimensional dynamics of MAPK information‐processing systems

    Article • WIREs Systems Biology and Medicine, May 2009, Wiley

    Marc Birtwistle, Professor Boris N. Kholodenko

  21. Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses

    Article • Molecular Systems Biology, November 2007, EMBO

    Marc Birtwistle, Professor Boris N. Kholodenko