All Stories

  1. Neurite outgrowth inhibitor-B (Nogo-B) in physiology and disease.
  2. The Prevalence and Progression of Microvascular Complications and the Interaction With Ethnicity and Socioeconomic Status in People With Type 2 Diabetes: A Systematic Review and Meta‐Analysis
  3. Nogo-B Promotes Endoplasmic Reticulum Stress-Mediated Autophagy in Endothelial Cells of Diabetic Nephropathy
  4. Ten years trajectories of estimated glomerular filtration rate (eGFR) in a multiethnic cohort of people with type 1 diabetes and preserved renal function
  5. Diabetic kidney disease in type 1 diabetes: challenges and differences from type 2 diabetes
  6. Effect of active vitamin-D on left ventricular mass index: Results of a randomized controlled trial in type 2 diabetes and chronic kidney disease
  7. Reduced Levels of the Antiaging Hormone Klotho are Associated With Increased Aortic Stiffness in Diabetic Kidney Disease
  8. Effect of Continuous Positive Airway Pressure on Glucose and Lipid Profiles in Patients With Obstructive Sleep Apnoea: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
  9. The Pillars for Renal Disease Treatment in Patients with Type 2 Diabetes
  10. Renal disease in patients with type 2 diabetes: Magnitude of the problem, risk factors and preventive strategies
  11. Impact of treatment with active vitamin D calcitriol on bone turnover markers in people with type 2 diabetes and stage 3 chronic kidney disease
  12. Metabolism, Clinical and Experimental: seventy years young and growing
  13. Does Dapagliflozin influence arterial stiffness and levels of circulating anti-aging hormone soluble Klotho in people with type 2 diabetes and kidney disease? Results of a randomized parallel group clinical trial
  14. Effect of calcitriol treatment on arterial stiffness in people with type 2 diabetes and stage 3 chronic kidney disease
  15. African Caribbean Ethnicity Is an Independent Predictor of Significant Decline in Kidney Function in People With Type 1 Diabetes
  16. Diabetes and Kidney disease: metformin
  17. Kidney disease in diabetes: From mechanisms to clinical presentation and treatment strategies
  18. Vascular growth factors as potential new treatment in cardiorenal syndrome in diabetes
  19. Calcitonin Gene-Related Peptide Protects Against Cardiovascular Dysfunction Independently of Nitric Oxide In Vivo
  20. Mitochondrial dysfunction as a mechanistic biomarker in patients with non-alcoholic fatty liver disease (NAFLD)
  21. The endoplasmic reticulum stress and the unfolded protein response in kidney disease: Implications for vascular growth factors
  22. A case for measuring both cellular and cell‐free mitochondrial DNA as a disease biomarker in human blood
  23. Diabetic Nephropathy: An Overview
  24. Overexpression of Circulating Soluble Nogo-B Improves Diabetic Kidney Disease by Protecting the Vasculature
  25. Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
  26. Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial
  27. VEGFC Reduces Glomerular Albumin Permeability and Protects Against Alterations in VEGF Receptor Expression in Diabetic Nephropathy
  28. The Future: Experimental Therapies for Renal Disease in Diabetes
  29. Reduced Levels of Anti-Ageing Hormone Klotho Predict Renal Function Decline in Type 2 Diabetes
  30. Diabetic nephropathy: Is there a role for oxidative stress?
  31. RETRACTED ARTICLE: Annexin A1 attenuates microvascular complications through restoration of Akt signalling in a murine model of type 1 diabetes
  32. A pragmatic lifestyle modification programme reduces the incidence of predictors of cardio-metabolic disease and dysglycaemia in a young healthy urban South Asian population: a randomised controlled trial
  33. Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
  34. Increased Arterial Stiffness is an Independent Predictor of Renal Function Decline in Patients With Type 2 Diabetes Mellitus Younger Than 60 Years
  35. Perturbations of the anti-ageing hormone Klotho in patients with type 1 diabetes and microalbuminuria
  36. Management of patients with diabetes and CKD: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference
  37. Diabetic Nephropathy: Perspective on Novel Molecular Mechanisms
  38. The anti-ageing hormone klotho induces Nrf2-mediated antioxidant defences in human aortic smooth muscle cells
  39. Improvements in stage of change correlate to changes in dietary intake and clinical outcomes in a 5-year lifestyle intervention in young high-risk Sri Lankans
  40. The effect of dietary changes on distinct components of the metabolic syndrome in a young Sri Lankan population at high risk of CVD
  41. Angiopoietins and diabetic nephropathy
  42. Diabetic Nephropathy: Proteinuria, Inflammation, and Fibrosis
  43. Efficacy and safety of canagliflozin when used in conjunction with incretin-mimetic therapy in patients with type 2 diabetes
  44. Altered circulating mitochondrial DNA and increased inflammation in patients with diabetic retinopathy
  45. Vascular growth factors play critical roles in kidney glomeruli
  46. Diabetic nephropathy: What does the future hold?
  47. A Pilot Study to Evaluate the Efficacy of Class IV Lasers on Nonhealing Neuroischemic Diabetic Foot Ulcers in Patients With Type 2 Diabetes
  48. The effect of CCR2 inhibitor CCX140-B on residual albuminuria in patients with type 2 diabetes and nephropathy: a randomised trial
  49. Preventing diabetic renal disease: the potential reno-protective effects of SGLT2 inhibitors
  50. Altered Mitochondrial Function, Mitochondrial DNA and Reduced Metabolic Flexibility in Patients With Diabetic Nephropathy
  51. Clinical Practice Guideline on management of patients with diabetes and chronic kidney disease stage 3b or higher (eGFR <45 mL/min)
  52. Beat it early: putative renoprotective haemodynamic effects of oral hypoglycaemic agents
  53. A new chance to beat diabetic kidney disease: innate immunity and MCP-1: a matter of good and bad macrophages?
  54. Influence of depression and anxiety on circulating endothelial progenitor cells in patients with acute coronary syndromes
  55. Diabetes mellitus, a complex and heterogeneous disease, and the role of insulin resistance as a determinant of diabetic kidney disease
  56. N-3 PUFA increase bioavailability and function of endothelial progenitor cells
  57. An Ongoing Role of α-Calcitonin Gene–Related Peptide as Part of a Protective Network Against Hypertension, Vascular Hypertrophy, and Oxidative Stress
  58. Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease
  59. Glucose-lowering drugs in patients with chronic kidney disease: a narrative review on pharmacokinetic properties
  60. Alogliptin after Acute Coronary Syndrome in Patients with Type 2 Diabetes
  61. Targeted Glomerular Angiopoietin-1 Therapy for Early Diabetic Kidney Disease
  62. Effect of Renin-Angiotensin System Blockade on Soluble Klotho in Patients with Type 2 Diabetes, Systolic Hypertension, and Albuminuria
  63. Albuminuria is associated with too few glomeruli and too much testosterone
  64. Lower endothelial progenitor cell number, family history of cardiovascular disease and reduced HDL-cholesterol levels are associated with shorter leukocyte telomere length in healthy young adults
  65. A Role for TRPV1 in Influencing the Onset of Cardiovascular Disease in Obesity
  66. VEGF and angiopoietins in diabetic glomerulopathy: How far for a new treatment?
  67. Effect of Spironolactone and Amiloride on Thiazolidinedione-Induced Fluid Retention in South Indian Patients with Type 2 Diabetes
  68. Pioglitazone Improves In Vitro Viability and Function of Endothelial Progenitor Cells from Individuals with Impaired Glucose Tolerance
  69. Podocytes and the struggle against glucose toxicity: New targets for treatment?
  70. Cellular and molecular mechanisms of diabetic glomerulopathy
  71. High Prevalence of Cardio-Metabolic Risk Factors in a Young Urban Sri-Lankan Population
  72. Elevated levels of renal and circulating Nop-7-associated 2 (NSA2) in rat and mouse models of diabetes, in mesangial cells in vitro and in patients with diabetic nephropathy
  73. DIABRISK - SL Prevention of cardio-metabolic disease with life style modification in young urban Sri Lankan's - study protocol for a randomized controlled trial
  74. Reduced circulating endothelial progenitor cell number in healthy young adult hyperinsulinemic men
  75. Circulating Vascular Progenitor Cells and Central Arterial Stiffness in Polycystic Ovary Syndrome
  76. Endothelial Factors and Diabetic Nephropathy
  77. Prandial inhaled insulin plus basal insulin glargine versus twice daily biaspart insulin for type 2 diabetes: a multicentre randomised trial
  78. Renin angiotensin aldosterone system (RAAS) inhibitors in the prevention of early renal disease in diabetes
  79. Circulating Vascular Progenitor Cells in Patients With Type 1 Diabetes and Microalbuminuria
  80. Peroxisome Proliferator-Activated Receptor-γ Agonist Rosiglitazone Prevents Albuminuria but Not Glomerulosclerosis in Experimental Diabetes
  81. P-67: Use of recombinant adenovirus-mediated gene transfer to investigate the effects of dominant negative ras on the activation of PI3 kinase and glucose transport in 3T3L1 adipocytes
  82. Mechanical forces and TGF 1 reduce podocyte adhesion through  3 1 integrin downregulation
  83. Inducible Overexpression of sFlt-1 in Podocytes Ameliorates Glomerulopathy in Diabetic Mice
  84. Molecular mechanisms of proteinuria in diabetes
  85. Roles of Angiopoietins in Kidney Development and Disease: Figure 1.
  86. Angiopoietin-1 therapy enhances fibrosis and inflammation following folic acid-induced acute renal injury
  87. ACCORD and ADVANCE: a tale of two studies on the merits of glycaemic control in type 2 diabetic patients
  88. Fluorescence-based sensing of glucose using engineered glucose/galactose-binding protein: A comparison of fluorescence resonance energy transfer and environmentally sensitive dye labelling strategies
  89. Future Strategies to Prevent Renal Microvascular Disease Complications in Diabetes
  90. Serum intact parathyroid hormone in diabetic patients on haemodialysis: what is the treatment goal?
  91. Mechanical Forces in Diabetic Kidney Disease
  92. Podocyte-Specific Expression of Angiopoietin-2 Causes Proteinuria and Apoptosis of Glomerular Endothelia
  93. The link between mechanical stretch and glucose metabolism--a conceptual advance in understanding diabetic (and non diabetic?) renal disease
  94. Glucose induces increases in levels of the transcriptional repressor Id2 via the hexosamine pathway
  95. The link between Glut-1 and hypertension in diabetic nephropathy
  96. Glucose-dependent changes in NAD(P)H-related fluorescence lifetime of adipocytes and fibroblasts in vitro: Potential for non-invasive glucose sensing in diabetes mellitus
  97. Mechanical Stretch Induces Monocyte Chemoattractant Activity via an NF-κB-Dependent Monocyte Chemoattractant Protein-1-Mediated Pathway in Human Mesangial Cells
  98. Nateglinide alone or with metformin safely improves glycaemia to target in patients up to an age of 84
  99. Non-Invasive Glucose Monitoring by NAD(P)H Autofluorescence Spectroscopy in Fibroblasts and Adipocytes: A Model for Skin Glucose Sensing
  100. GLUT-1 Overexpression
  101. IGF-I induces vascular endothelial growth factor in human mesangial cells via a Src-dependent mechanism11See Editorial by Cooper and Thomas, p. 1584.
  102. P38 mitogen-activated protein kinase mediates hexosamine-induced TGFβ1 mRNA expression in human mesangial cells
  103. Mechanical stretch-induced fibronectin and transforming growth factor-beta1 production in human mesangial cells is p38 mitogen-activated protein kinase-dependent.
  104. Inhibition of DNA Synthesis by a Farnesyltransferase Inhibitor Involves Inhibition of the p70s6k Pathway
  105. Multiple Signal Transduction Pathways Link Na+/K+-ATPase to Growth-related Genes in Cardiac Myocytes
  106. Activation of the Ras Mitogen-activated Protein Kinase-Ribosomal Protein Kinase Pathway Is Not Required for the Repression of Phosphoenolpyruvate Carboxykinase Gene Transcription by Insulin
  107. Amelioration of Insulin Resistance in Streptozotocin Diabetic Mice by Transgenic Overexpression of GLUT4 Driven by an Adipose-Specific Promoter1
  108. High-Fat Feeding Impairs Insulin-Stimulated GLUT4 Recruitment via an Early Insulin-Signaling Defect
  109. Adenovirus-Mediated Gene Transfer of Dominant Negative Rasasn17in 3T3L1 Adipocytes Does Not Alter Insulin-Stimulated PI3-Kinase Activity or Glucose Transport
  110. Overexpression of Ha-ras Selectively in Adipose Tissue of Transgenic Mice
  111. Over-expression of GLUT4 selectively in adipose tissue in transgenic mice: Implications for nutrient partitioning
  112. Insulin Regulation of Phosphoenolpyruvate Carboxykinase Gene Expression Does Not Require Activation of the Ras/Mitogen-activated Protein Kinase Signaling Pathway
  113. High level overexpression of glucose transporter-4 driven by an adipose-specific promoter is maintained in transgenic mice on a high fat diet, but does not prevent impaired glucose tolerance.
  114. Alcohol Intake Impairs Glucose Counterregulation During Acute Insulin-Induced Hypoglycemia in IDDM Patients: Evidence for a Critical Role of Free Fatty Acids
  115. Effects of different plasma glucose concentrations on lipolytic and ketogenic responsiveness to epinephrine in type I (insulin-dependent) diabetic subjects.
  116. Ketone Body Metabolism in NIDDM: Effect of Sulfonylurea Treatment
  117. The effects of different plasma insulin concentrations on lipolytic and ketogenic responses to epinephrine in normal and Type 1 (insulin-dependent) diabetic humans
  118. Renal metabolism of C peptide in type I (insulin-dependent) diabetic patients
  119. Effects of chronic alcohol intake on carbohydrate and lipid metabolism in subjects with type ii (non-insulin-dependent) diabetes
  120. Habitual leisure‐time physical activity is associated with differences in various risk factors for coronary artery disease
  121. Hyperinsulinemia and Coronary Artery Disease
  122. Risk Factors for Coronary Artery Disease in Healthy Persons with Hyperinsulinemia and Normal Glucose Tolerance