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  1. Why diabetes matters in dementia studies. Excluding diabetes status masks regional mitochondrial DNA copy number changes in human hippocampus, amygdala, and cerebellum in Alzheimers disease

    Article • June 2026, openRxiv

    Dr Afshan N Malik

  2. Accurate quantification of canine mitochondrial DNA copy number and its evaluation as a biomarker of brain injury

    Article • February 2026, openRxiv

    Dr Afshan N Malik

  3. Tackling overweight and obesity in the youth with the PAS GRAS project

    Article • Nature Medicine, June 2025, Springer Science + Business Media

    Dr Afshan N Malik

  4. Co-regulation and synteny of GFM2 and NSA2 links ribosomal function in mitochondria and the cytosol with chronic kidney disease

    Article • Extremophiles, October 2024, Springer Science + Business Media

    Dr Afshan N Malik

  5. Mitochondrial DNA – novel mechanisms of kidney damage and potential biomarker

    Article • Current Opinion in Nephrology & Hypertension, September 2023, Wolters Kluwer Health

    Dr Afshan N Malik

  6. Stress‐dependent macromolecular crowding in the mitochondrial matrix

    Article • The EMBO Journal, February 2023, EMBO

    Dr Afshan N Malik

  7. Viscosity and macromolecular crowding in the mitochondrial matrix: Impact on protein diffusion and structure

    Article • Biochimica et Biophysica Acta (BBA) - Bioenergetics, September 2022, Elsevier

    Dr Afshan N Malik

  8. Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy

    Article • PLOS One, January 2022, PLOS

    Dr Afshan N Malik

  9. Mitochondria, oxidative stress and nonalcoholic fatty liver disease: A complex relationship

    Article • European Journal of Clinical Investigation, June 2021, Wiley

    Dr Afshan N Malik

  10. Accurate Measurement of Cellular and Cell-Free Circulating Mitochondrial DNA Content from Human Blood Samples Using Real-Time Quantitative PCR

    Article • January 2021, Springer Science + Business Media

    Dr Afshan N Malik

  11. Supplementation with a prebiotic (polydextrose) in obese mouse pregnancy improves maternal glucose homeostasis and protects against offspring obesity

    Article • International Journal of Obesity, October 2020, Springer Science + Business Media

    Dr Afshan N Malik

  12. A case for measuring both cellular and cell‐free mitochondrial DNA as a disease biomarker in human blood

    Article • The FASEB Journal, July 2020, Wiley

    luigi gnudi, Dr Afshan N Malik

  13. Optimizing beta cell function through mesenchymal stromal cell-mediated mitochondria transfer

    Article • Stem Cells, January 2020, Wiley

    Dr Afshan N Malik

  14. Effects of thyroid hormone on mitochondria and metabolism of human preimplantation embryos

    Article • Stem Cells, December 2019, Wiley

    Dr Hannah Rosa, Dr Afshan N Malik

  15. The Detection and Partial Localisation of Heteroplasmic Mutations in the Mitochondrial Genome of Patients with Diabetic Retinopathy

    Article • International Journal of Molecular Sciences, December 2019, MDPI AG

    Dr Afshan N Malik

  16. A Diet Induced Maladaptive Increase in Hepatic Mitochondrial DNA Precedes OXPHOS Defects and May Contribute to Non-Alcoholic Fatty Liver Disease

    Article • Cells, October 2019, MDPI AG

    Dr Hannah Rosa, Dr Afshan N Malik

  17. Regional mitochondrial DNA and cell-type changes in post-mortem brains of non-diabetic Alzheimer’s disease are not present in diabetic Alzheimer’s disease

    Article • Scientific Reports, August 2019, Springer Science + Business Media

    Dr Afshan N Malik, Dr Hannah Rosa

  18. Reduced mitochondrial lipid oxidation leads to fat accumulation in myosteatosis

    Article • The FASEB Journal, July 2019, Federation of American Societies For Experimental Biology (FASEB)

    Dr Afshan N Malik

  19. Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

    Article • The American Journal of Human Genetics, January 2019, Elsevier

    Dr Afshan N Malik

  20. Mitochondrial DNA as a Potential Translational Biomarker of Mitochondrial Dysfunction in Drug-Induced Toxicity Studies

    Article • February 2018, Wiley

    Dr Afshan N Malik

  21. Potential Mechanisms of Mitochondrial DNA Mediated Acquired Mitochondrial Disease

    Article • January 2018, Springer Science + Business Media

    Dr Afshan N Malik, Dr Hannah Rosa

  22. Mitochondrial genes are altered in blood early in Alzheimer's disease

    Article • Neurobiology of Aging, May 2017, Elsevier

    Dr Afshan N Malik

  23. Hyperglycemia induced damage to mitochondrial respiration in renal mesangial and tubular cells: Implications for diabetic nephropathy

    Article • Redox Biology, December 2016, Elsevier

    Dr Afshan N Malik

  24. Accurate quantification of mouse mitochondrial DNA without co-amplification of nuclear mitochondrial insertion sequences

    Article • Mitochondrion, July 2016, Elsevier

    Dr Afshan N Malik

  25. Altered circulating mitochondrial DNA and increased inflammation in patients with diabetic retinopathy

    Article • Diabetes Research and Clinical Practice, December 2015, Elsevier

    Dr Afshan N Malik, luigi gnudi

  26. Equilibrative nucleoside transporter 3 depletion in β-cells impairs mitochondrial function and promotes apoptosis: Relationship to pigmented hypertrichotic dermatosis with insulin-dependent diabetes

    Article • Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, October 2015, Elsevier

    Dr Afshan N Malik

  27. Altered Mitochondrial Function, Mitochondrial DNA and Reduced Metabolic Flexibility in Patients With Diabetic Nephropathy

    Article • EBioMedicine, June 2015, Elsevier

    Dr Afshan N Malik, luigi gnudi

  28. Understanding the Implications of Mitochondrial DNA Variation in the Health of Black Southern African Populations: The 2014 Workshop

    Article • Human Mutation, April 2015, Wiley

    Dr Afshan N Malik

  29. Accurate Measurement of Circulating Mitochondrial DNA Content from Human Blood Samples Using Real-Time Quantitative PCR

    Article • January 2015, Springer Science + Business Media

    Dr Afshan N Malik

  30. Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?

    Article • Mitochondrion, September 2013, Elsevier

    Dr Afshan N Malik

  31. Nop-7-associated 2 (NSA2), a candidate gene for diabetic nephropathy, is involved in the TGFβ1 pathway

    Article • The International Journal of Biochemistry & Cell Biology, March 2013, Elsevier

    Dr Afshan N Malik

  32. 10 Mitochondrial dysfunction in diabetic nephropathy

    Article • Heart, November 2011, BMJ

    Dr Afshan N Malik

  33. Elevated levels of renal and circulating Nop-7-associated 2 (NSA2) in rat and mouse models of diabetes, in mesangial cells in vitro and in patients with diabetic nephropathy

    Article • Diabetologia, November 2011, Springer Science + Business Media

    Dr Afshan N Malik, luigi gnudi

  34. Mitochondrial DNA as a non-invasive biomarker: Accurate quantification using real time quantitative PCR without co-amplification of pseudogenes and dilution bias

    Article • Biochemical and Biophysical Research Communications, August 2011, Elsevier

    Dr Afshan N Malik

  35. Hyperglycemia induces elevated expression of thyroid hormone binding protein in vivo in kidney and heart and in vitro in mesangial cells

    Article • Biochemical and Biophysical Research Communications, January 2010, Elsevier

    Dr Afshan N Malik

  36. Increased peripheral blood mitochondrial DNA in type 2 diabetic patients with nephropathy

    Article • Diabetes Research and Clinical Practice, November 2009, Elsevier

    Dr Afshan N Malik

  37. Glucose regulation of CDK7, a putative thiol related gene, in experimental diabetic nephropathy

    Article • Biochemical and Biophysical Research Communications, May 2007, Elsevier

    Dr Afshan N Malik

  38. Glucose regulation of β-defensin-1 mRNA in human renal cells

    Article • Biochemical and Biophysical Research Communications, February 2007, Elsevier

    Dr Afshan N Malik

  39. Scaphoid views: a need for standardisation

    Article • Annals of The Royal College of Surgeons of England, May 2004, Royal College of Surgeons of England

    Dr Afshan N Malik

  40. Elevated levels of beta defensin-1 mRNA in diabetic kidneys of GK rats

    Article • Biochemical and Biophysical Research Communications, October 2003, Elsevier

    Dr Afshan N Malik

  41. Isolation of Diabetes-Associated Kidney Genes Using Differential Display

    Article • Biochemical and Biophysical Research Communications, March 1997, Elsevier

    Dr Afshan N Malik

  42. Molecular characterisation of theXenopus laevis chaperonin geneCctg

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, November 1996, Elsevier

    Dr Afshan N Malik

  43. Drosophila melanogaster P1 genomic clone DS05563 contains the chaperonin-encoding gene Cctg

    Article • Gene, June 1996, Elsevier

    Dr Afshan N Malik

  44. Cloning, structure and mRNA expression of human Cctg, which encodes the chaperonin subunit CCTγ

    Article • Biochemical Journal, January 1996, Portland Press Ltd.

    Dr Afshan N Malik

  45. Identification of differentially expressed genes during the progression of diabetic nephropathy

    Article • Biochemical Society Transactions, August 1994, Portland Press Ltd.

    Dr Afshan N Malik

  46. THE GENE ENCODING HUMAN RIBOSOMAL PROTEIN L27 IS DEVELOPMENTALLY REGULATED IN HUMAN KIDNEY

    Article • Biochemical Society Transactions, August 1994, Portland Press Ltd.

    Dr Afshan N Malik

  47. The Tcp-1-related gene, Cctg, maps to mouse Chromosome 3

    Article • Mammalian Genome, August 1994, Springer Science + Business Media

    Dr Afshan N Malik

  48. Cloning and nucleotide sequence of a full length cDNA encoding ribosomal protein L27 from human fetal kidney

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, April 1994, Elsevier

    Dr Afshan N Malik

  49. Parathyroid hormone related peptide gene expression in human fetal and adult heart

    Article • Cardiovascular Research, July 1993, European Society of Cardiology

    Dr Afshan N Malik

  50. Parathyroid hormone-related peptide: Expression in fetal and neonatal development

    Article • The Journal of Pathology, July 1992, Wiley

    Dr Afshan N Malik

  51. A discordance between the human muscle NCAM sequence and those seen in other NCAM cDNA clones

    Article • Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, February 1992, Elsevier

    Dr Afshan N Malik

  52. Molecular genetics of Pseudomonas syringae pathovar pisi: plasmid involvement in cultivar-specific incompatibility

    Article • Journal of General Microbiology, September 1991, Society for General Microbiology

    Dr Afshan N Malik

  53. Parathyroid hormone-related peptide in normal human fetal development

    Article • Journal of Molecular Endocrinology, December 1990, Bioscientifica

    Dr Afshan N Malik

  54. Molecular cloning of a human thyrotropin receptor cDNA fragment

    Article • FEBS Letters, May 1990, Wiley

    Dr Afshan N Malik

  55. A simple high yield method for the preparation of lambda gt10 DNA suitable for subcloning, amplification and direct sequencing

    Article • Nucleic Acids Research, January 1990, Oxford University Press (OUP)

    Dr Afshan N Malik