All Stories

  1. MagmaFlow : A desktop platform for artificial intelligence‐driven expression analysis
  2. Fecal Detection of Calprotectin Subunits Links Inflammatory Bowel Disease Activity With Chronicity of Intestinal Inflammation
  3. FAPI Tracer en Vogue: Evaluating [68Ga]Ga-DATA5m.SA.FAPi for Molecular Imaging of Pulmonary Fibrosis
  4. Fatty acid-binding protein 5 aggravates psoriasis and psoriasis-like disease through ferroptosis
  5. A Sex-Specific Anti-Inflammatory Role for p62 in Psoriasis-Like Disease
  6. Fosl1 is a transcriptional effector of BRAFV600E-driven intestinal tumorigenesis
  7. Nutritional c‐Fos Induction Rewires Hepatic Metabolism and Can Promote Obesity‐Associated Hepatocellular Carcinoma
  8. Chronic skin and systemic inflammation modulated by S100A8 and S100A9 complexes
  9. A new effLuc/Kate dual reporter allele for tumor imaging in mice
  10. c-Jun and Fra-2 pair up to Myc-anistically drive HCC
  11. c-Jun and Fra-2 Pair Up to Myc-anistically Drive HCC    
  12. Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity
  13. Liver cancer development driven by the AP-1/c-Jun~Fra-2 dimer through c-Myc (Author copy)  
  14. Molecular signalling pathway of liver cancer development decoded
  15. Metabolic rewiring controlled by c-Fos governs cartilage integrity in osteoarthritis
  16. Open Thy Lattice Osteoclast, Resorb me!
  17. Keratinocyte-derived S100A9 modulates neutrophil infiltration and affects psoriasis-like skin and joint disease
  18. An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia
  19. TPL-2 Inhibits IFN-β Expression via an ERK1/2-TCF-FOS Axis in TLR4-Stimulated Macrophages
  20. Targeting AP-1 transcription factors by CRISPR in the prostate
  21. NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
  22. Calprotectin: from biomarker to biological function
  23. Sequestosome 1/p62 enhances chronic skin inflammation
  24. JunB is a key regulator of multiple myeloma bone marrow angiogenesis
  25. Psoriatic skin inflammation is promoted by c‐Jun/AP‐1‐dependent CCL2 and IL‐23 expression in dendritic cells
  26. In vivo CRISPR inactivation of Fos promotes prostate cancer progression by altering the associated AP-1 subunit Jun
  27. Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment
  28. Wnt signaling and Loxl2 promote aggressive osteosarcoma
  29. Fra-2–expressing macrophages promote lung fibrosis
  30. EGFR is required for FOS‐dependent bone tumor development via RSK2/CREB signaling
  31. Virus Delivery of CRISPR Guides to the Murine Prostate for Gene Alteration
  32. EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation
  33. Transcriptional regulation by NR5A2 links differentiation and inflammation in the pancreas
  34. Fra-2 negatively regulates postnatal alveolar septation by modulating myofibroblast function
  35. Transcriptional regulation by NR5A2 couples cell differentiation and inflammation in the pancreas
  36. Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation
  37. The AP-1 transcription factor JunB is essential for multiple myeloma cell proliferation and drug resistance in the bone marrow microenvironment
  38. Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress
  39. News and views on EMT Fra-1 controls EMT in mammary epithelial cells
  40. Osteogenic capillaries orchestrate growth plate-independent ossification of the malleus
  41. Characterization of Mouse Model-Derived Osteosarcoma (OS) Cells In Vitro and In Vivo
  42. Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2
  43. Loss of JUNB/AP-1 promotes invasive prostate cancer
  44. Inhibition of De Novo NAD + Synthesis by Oncogenic URI Causes Liver Tumorigenesis through DNA Damage
  45. Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression
  46. A FATal AP-1 dimer switch in hepatosteatosis
  47. Regulation of Steatohepatitis and PPARγ Signaling by Distinct AP-1 Dimers
  48. JUNB/AP-1 controls IFN-γ during inflammatory liver disease
  49. Activator protein 1 transcription factor fos-related antigen 1 (fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism
  50. Inflammation-mediated skin tumorigenesis induced by epidermal c-Fos
  51. Hepatitis C virus core+1/ARF protein decreases hepcidin transcription through an AP1 binding site
  52. Mouse models for liver cancer
  53. Osteoblast-specific expression of Fra-2/AP-1 controls Adiponectin/Osteocalcin expression and affects metabolism
  54. Liver cancer initiation is controlled by AP-1 through SIRT6-dependent inhibition of survivin
  55. Differentiation-induced skin cancer suppression by FOS, p53, and TACE/ADAM17
  56. Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation
  57. Functions of Fos phosphorylation in bone homeostasis, cytokine response and tumourigenesis
  58. Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production
  59. TNFα shedding and epidermal inflammation are controlled by Jun proteins
  60. JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells
  61. Osteoclast size is controlled by Fra-2 through LIF/LIF-receptor signalling and hypoxia
  62. c-Jun Controls Histone Modifications, NF-κB Recruitment, and RNA Polymerase II Function To Activate the ccl2 Gene
  63. p38α: A Suppressor of Cell Proliferation and Tumorigenesis
  64. Dimer Composition and Promoter Context Contribute to Functional Cooperation between AP-1 and NFAT
  65. Targeting c-Jun and JunB proteins as potential anticancer cell therapy
  66. p38α suppresses normal and cancer cell proliferation by antagonizing the JNK–c-Jun pathway
  67. Role of heterodimerization of c-Fos and Fra1 proteins in osteoclast differentiation
  68. Fra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcription
  69. Essential role of RSK2 in c-Fos–dependent osteosarcoma development
  70. AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene
  71. Distinct functions of junD in cardiac hypertrophy and heart failure
  72. Fos and Jun Proteins Are Specifically Expressed During Differentiation of Human Keratinocytes
  73. Promoter Specificity and Biological Activity of Tethered AP-1 Dimers
  74. Functional cooperation between JunD and NF-κB in rat hepatocytes
  75. Cell cycle-dependent variations in c-Jun and JunB phosphorylation: a role in the control of cyclin D1 expression
  76. Stress-activated protein kinases are negatively regulated by cell density
  77. Induction of apoptosis by the transcription factor c-Jun
  78. Identification of a Novel 135-kDa Grb2-binding Protein in Osteoclasts