All Stories

  1. Engineered antibodies bypass bacterial immune evasion to drive complement-mediated protection against lethal infections

    Article • Science Translational Medicine, June 2026, American Association for the Advancement of Science

    Dr Larry S. McDaniel

  2. Oligopeptide Transporters of Nonencapsulated Streptococcus pneumoniae Regulate CbpAC and PspA Expression and Reduce Complement-Mediated Clearance

    Article • mBio, February 2023, ASM Journals

    Dr Larry S. McDaniel

  3. If Not Now, When? Nonserotype Pneumococcal Protein Vaccines

    Article • Open Forum Infectious Diseases, December 2021, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  4. Prophylactic Inhibition of Colonization by Streptococcus pneumoniae with the Secondary Bile Acid Metabolite Deoxycholic Acid

    Article • Infection and Immunity, November 2021, ASM Journals

    Dr Larry S. McDaniel

  5. Prophylactic inhibition of colonization by Streptococcus pneumoniae with the secondary bile acid metabolite deoxycholic acid

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Dr Larry S. McDaniel

  6. Otitis Media and Ear Infections: Bacteria

    Article • January 2021, Elsevier

    Dr Larry S. McDaniel

  7. Hydrogen Peroxide Production by Streptococcus pneumoniae Results in Alpha-hemolysis by Oxidation of Oxy-hemoglobin to Met-hemoglobin

    Article • mSphere, December 2020, ASM Journals

    Dr Larry S. McDaniel

  8. Hydrogen peroxide production by Streptococcus pneumoniae results in alpha-hemolysis by oxidation of oxy-hemoglobin to met-hemoglobin

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Dr Larry S. McDaniel

  9. Mucosal Vaccines for Streptococcus pneumoniae

    Article • January 2020, Elsevier

    Dr Larry S. McDaniel

  10. The Modified Surface Killing Assay Distinguishes between Protective and Nonprotective Antibodies to PspA

    Article • mSphere, December 2019, ASM Journals

    Dr Larry S. McDaniel

  11. Selective pressure: Rise of the nonencapsulated pneumococcus

    Article • PLoS Pathogens, August 2019, PLOS

    Dr Larry S. McDaniel

  12. Pulmonary Disease Associated With Nonencapsulated Streptococcus pneumoniae

    Article • Open Forum Infectious Diseases, June 2018, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  13. Pseudomonas aeruginosa and Streptococcus pneumoniae coinfection

    Article • mSphere, May 2018, ASM Journals

    Dr Larry S. McDaniel

  14. Invasive Potential of Nonencapsulated Streptococcus pneumoniae

    Article • mBio, January 2018, ASM Journals

    Dr Larry S. McDaniel

  15. Polyamine transporter potABCD is required for virulence of encapsulated but not nonencapsulated Streptococcus pneumoniae

    Article • PLOS One, June 2017, PLOS

    Dr Larry S. McDaniel

  16. Should Pneumococcal Vaccines Eliminate Nasopharyngeal Colonization?

    Article • mBio, May 2016, ASM Journals

    Dr Larry S. McDaniel

  17. Surface Proteins and Pneumolysin of Encapsulated and Nonencapsulated Streptococcus pneumoniae Mediate Virulence in a Chinchilla Model of Otitis Media

    Article • Frontiers in Cellular and Infection Microbiology, May 2016, Frontiers

    Dr Larry S. McDaniel

  18. NonencapsulatedStreptococcus pneumoniae: Emergence and Pathogenesis

    Article • mBio, March 2016, ASM Journals

    Dr Larry S. McDaniel

  19. Nonencapsulated Streptococcus pneumoniae as a cause of chronic adenoiditis

    Article • IDCases, January 2016, Elsevier

    Dr Larry S. McDaniel

  20. Immunization with Pneumococcal Surface Protein K of Nonencapsulated Streptococcus pneumoniae Provides Protection in a Mouse Model of Colonization

    Article • Clinical and Vaccine Immunology, August 2015, ASM Journals

    Dr Larry S. McDaniel

  21. Nonencapsulated Streptococcus pneumoniae Cause Acute Otitis Media in the Chinchilla That Is Enhanced by Pneumococcal Surface Protein K

    Article • Open Forum Infectious Diseases, June 2014, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  22. Choline-Binding Proteins

    Article • April 2014, ASM Journals

    Dr Larry S. McDaniel

  23. Draft Genome Sequences of Five Multilocus Sequence Types of Nonencapsulated Streptococcus pneumoniae

    Article • Genome Announcements, July 2013, ASM Journals

    Dr Larry S. McDaniel

  24. The Cholesterol-Dependent Cytolysin Pneumolysin from Streptococcus pneumoniae Binds to Lipid Raft Microdomains in Human Corneal Epithelial Cells

    Article • PLOS One, April 2013, PLOS

    Dr Larry S. McDaniel

  25. Serine Protease PKF of Acinetobacter baumannii Results in Serum Resistance and Suppression of Biofilm Formation

    Article • The Journal of Infectious Diseases, January 2013, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  26. PspK of Streptococcus pneumoniae Increases Adherence to Epithelial Cells and Enhances Nasopharyngeal Colonization

    Article • Infection and Immunity, October 2012, ASM Journals

    Dr Larry S. McDaniel

  27. 66-P

    Article • Human Immunology, October 2012, Elsevier

    Dr Larry S. McDaniel

  28. Active Immunization with Pneumolysin versus 23-Valent Polysaccharide Vaccine for Streptococcus pneumoniae Keratitis

    Article • Investigative Ophthalmology & Visual Science, November 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Larry S. McDaniel

  29. Serum resistance and biofilm formation in clinical isolates ofAcinetobacter baumannii

    Article • FEMS Immunology & Medical Microbiology, April 2009, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  30. Cross-Sectional Study of Nasopharyngeal Carriage of Streptococcus pneumoniae in Human Immunodeficiency Virus-Infected Adults in the Conjugate Vaccine Era

    Article • Journal of Clinical Microbiology, September 2008, ASM Journals

    Dr Larry S. McDaniel

  31. Protection from Streptococcus pneumoniae Keratitis by Passive Immunization with Pneumolysin Antiserum

    Article • Investigative Ophthalmology & Visual Science, January 2008, Association for Research in Vision and Ophthalmology (ARVO)

    Dr Larry S. McDaniel

  32. Factor H Binding to PspC of Streptococcus pneumoniae Increases Adherence to Human Cell Lines In Vitro and Enhances Invasion of Mouse Lungs In Vivo

    Article • Infection and Immunity, June 2007, ASM Journals

    Dr Larry S. McDaniel

  33. Characterization of Streptococcus pneumoniae isolated from children with otitis media

    Article • FEMS Immunology & Medical Microbiology, June 2007, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  34. Immunization with PspA Incorporated into a Poly(Ethylene Oxide) Matrix Elicits Protective Immunity against Streptococcus pneumoniae

    Article • Clinical and Vaccine Immunology, April 2007, ASM Journals

    Dr Larry S. McDaniel

  35. Localization of PcsB of Streptococcus pneumoniae and Its Differential Expression in Response to Stress

    Article • Journal of Bacteriology, April 2007, ASM Journals

    Dr Larry S. McDaniel

  36. The genetic background of Streptococcus pneumoniae affects protection in mice immunized with PspA

    Article • FEMS Microbiology Letters, April 2007, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  37. Gene expression profiling of the response of Streptococcus pneumoniae to penicillin

    Article • Journal of Antimicrobial Chemotherapy, February 2007, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  38. Tex, a putative transcriptional accessory factor, is involved in pathogen fitness in Streptococcus pneumoniae

    Article • Microbial Pathogenesis, December 2006, Elsevier

    Dr Larry S. McDaniel

  39. Interaction of clinical isolates of Streptococcus pneumoniae with human complement factor H

    Article • FEMS Microbiology Letters, November 2006, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  40. 57-P

    Article • Human Immunology, October 2006, Elsevier

    Dr Larry S. McDaniel

  41. In Vivo Binding of Complement Regulator Factor H by Streptococcus pneumoniae

    Article • The Journal of Infectious Diseases, December 2005, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  42. THP-1 Monocytes Up-Regulate Intercellular Adhesion Molecule 1 in Response to Pneumolysin from Streptococcus pneumoniae

    Article • Infection and Immunity, October 2005, ASM Journals

    Dr Larry S. McDaniel

  43. Impact of peripheral blood IL-18 gene early expression on kidney allograft long-term outcome

    Article • Human Immunology, August 2005, Elsevier

    Dr Larry S. McDaniel

  44. Dual Roles of PspC, a Surface Protein of Streptococcus pneumoniae, in Binding Human Secretory IgA and Factor H

    Article • The Journal of Immunology, June 2004, The American Association of Immunologists

    Professor Sven Hammerschmidt, Dr Larry S. McDaniel

  45. Pneumococcal Disease

    Article • Infectious Diseases in Clinical Practice, March 2004, Wolters Kluwer Health

    Dr Larry S. McDaniel

  46. Relative Roles of Genetic Background and Variation in PspA in the Ability of Antibodies to PspA To Protect against Capsular Type 3 and 4 Strains of Streptococcus pneumoniae

    Article • Infection and Immunity, August 2003, ASM Journals

    Dr Anders P Hakansson, Dr Larry S. McDaniel

  47. Pneumolysin-Dependent and -Independent Gene Expression Identified by cDNA Microarray Analysis of THP-1 Human Mononuclear Cells Stimulated by Streptococcus pneumoniae

    Article • Infection and Immunity, April 2003, ASM Journals

    Dr Larry S. McDaniel

  48. Genetic Immunization with the Region Encoding the α-Helical Domain of PspA Elicits Protective Immunity againstStreptococcus pneumoniae

    Article • Infection and Immunity, September 2001, ASM Journals

    Dr Larry S. McDaniel

  49. Immunization with a plasmid expressing pneumococcal surface protein A (PspA) can elicit protection against fatal infection with Streptococcus pneumoniae

    Article • Gene Therapy, April 1997, Springer Science + Business Media

    Dr Larry S. McDaniel

  50. Oligonucleotides identify conserved and variable regions of pspA and pspA-like sequences of Streptococcus pneumoniae

    Article • Gene, April 1997, Elsevier

    Dr Larry S. McDaniel

  51. Evidence for the simultaneous expression of two PspAs by a clone of capsular serotype 6BStreptococcus pneumoniae

    Article • Microbial Pathogenesis, October 1996, Elsevier

    Dr Larry S. McDaniel

  52. Truncated Streptococcus pneumoniae PspA Molecules Elicit Cross-Protective Immunity against Pneumococcal Challenge in Mice

    Article • The Journal of Infectious Diseases, February 1996, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  53. Localization of protection-eliciting epitopes on PspA of Streptococcus pneumoniae between amino acid residues 192 and 260

    Article • Microbial Pathogenesis, November 1994, Elsevier

    Dr Larry S. McDaniel

  54. Molecular localization of variable and conserved regions of pspA and identification of additional pspA homologous sequences in Streptococcus pneumoniae

    Article • Microbial Pathogenesis, October 1992, Elsevier

    Dr Larry S. McDaniel

  55. Variation in the molecular weight of PspA (pneumococcal surface protein A) among Streptococcus pneumoniae

    Article • Microbial Pathogenesis, January 1990, Elsevier

    Dr Larry S. McDaniel

  56. Protein serotyping of Streptococcus pneumoniae based on reactivity to six monoclonal antibodies

    Article • Microbial Pathogenesis, September 1988, Elsevier

    Dr Larry S. McDaniel

  57. Role of Pneumococcal Surface Protein A in the Virulence of Streptococcus pneumoniae

    Article • Clinical Infectious Diseases, August 1988, Oxford University Press (OUP)

    Dr Larry S. McDaniel

  58. Analysis of a surface protein of Streptococcus pneumoniae recognised by protective monoclonal antibodies

    Article • Microbial Pathogenesis, December 1986, Elsevier

    Dr Larry S. McDaniel

  59. Monoclonal Antibodies against Surface Components of Streptococcus pneumoniae

    Article • January 1986, Elsevier

    Dr Larry S. McDaniel

  60. Monoclonal antibodies against protease-sensitive pneumococcal antigens can protect mice from fatal infection with Streptococcus pneumoniae

    Article • Journal of Experimental Medicine, August 1984, Rockefeller University Press

    Dr Larry S. McDaniel