All Stories

  1. In vivo proteomics identifies the competence regulon and AliB oligopeptide transporter as pathogenic factors in pneumococcal meningitis
  2. Homophilic protein interactions facilitate bacterial aggregation and IgG-dependent complex formation by the Streptococcus canis M protein SCM
  3. Pneumococcal Metabolic Adaptation and Colonization Are Regulated by the Two-Component Regulatory System 08
  4. Attachment of phosphorylcholine residues to pneumococcal teichoic acids and modification of substitution patterns by the phosphorylcholine esterase
  5. Platelets kill bacteria by bridging innate and adaptive immunity via platelet factor 4 and FcγRIIA
  6. Metabolic inventory of Streptococcus pneumoniae growing in a chemical defined environment
  7. Lipoteichoic acid deficiency permits normal growth but impairs virulence of Streptococcus pneumoniae
  8. Streptococcus pneumoniae two-component regulatory systems: The interplay of the pneumococcus with its environment
  9. Mapping the recognition domains of pneumococcal fibronectin-binding proteins PavA and PavB demonstrates a common pattern of molecular interactions with fibronectin type III repeats
  10. SCM, the M Protein of Streptococcus canis Binds Immunoglobulin G
  11. Role of purinergic signaling in experimental pneumococcal meningitis
  12. Special Issue on ‘Microbe-host interactions’
  13. Pulmonary Immunostimulation with MALP-2 in Influenza Virus-Infected Mice Increases Survival after Pneumococcal Superinfection
  14. Pneumococcal Adhesins PavB and PspC Are Important for the Interplay with Human Thrombospondin-1
  15. Pneumococcal Pili and Adhesins
  16. Exploitation of Host Signal Transduction Pathways Induced by Streptococcus pneumoniae
  17. Polyphosphates form antigenic complexes with platelet factor 4 (PF4) and enhance PF4-binding to bacteria
  18. Regulation of the Arginine Deiminase System by ArgR2 Interferes with Arginine Metabolism and Fitness ofStreptococcus pneumoniae
  19. Streptococcus pneumoniae–Induced Oxidative Stress in Lung Epithelial Cells Depends on Pneumococcal Autolysis and Is Reversible by Resveratrol
  20. Tuf of Streptococcus pneumoniae is a surface displayed human complement regulator binding protein
  21. Endocytosis of Streptococcus pneumoniae via the polymeric immunoglobulin receptor of epithelial cells relies on clathrin and caveolin dependent mechanisms
  22. Binding of vitronectin and Factor H to Hic contributes to immune evasion of Streptococcus pneumoniae serotype 3
  23. Structure of the pneumococcall,d-carboxypeptidase DacB and pathophysiological effects of disabled cell wall hydrolases DacA and DacB
  24. Leukocyte Attraction by CCL20 and Its Receptor CCR6 in Humans and Mice with Pneumococcal Meningitis
  25. Following in Real Time the Impact of Pneumococcal Virulence Factors in an Acute Mouse Pneumonia Model Using Bioluminescent Bacteria
  26. Influence of Impaired Lipoprotein Biogenesis on Surface and Exoproteome of Streptococcus pneumoniae
  27. Repeating Structures of the Major Staphylococcal Autolysin Are Essential for the Interaction with Human Thrombospondin 1 and Vitronectin
  28. Crystal structure of the pneumoccocal exposed lipoprotein thioredoxin sp_0659 (Etrx1) from Streptococcus pneumoniae strain TIGR4
  29. Crystal structure of the pneumoccocal exposed lipoprotein thioredoxin sp_1000 (Etrx2) from Streptococcus pneumoniae strain TIGR4 in complex with 2-hydroxyethyl disulfide
  30. The interaction between bacterial enolase and plasminogen promotes adherence of Streptococcus pneumoniae to epithelial and endothelial cells
  31. The choline-binding protein PspC of Streptococcus pneumoniae interacts with the C-terminal heparin-binding domain of vitronectin
  32. Elongation Factor Tu (Tuf) is a new virulence factor of Streptococcus pneumoniae that binds human complement factors, aids in immune evasion and host tissue invasion
  33. Crystal structure of the pneumoccocal exposed lipoprotein thioredoxin sp_1000 (Etrx2) from Streptococcus pneumoniae strain TIGR4 in complex with Cyclofos 3 TM
  34. Molecular architecture of Streptococcus pneumoniae surface thioredoxin-fold lipoproteins crucial for extracellular oxidative stress resistance and maintenance of virulence
  35. Exploitation of physiology and metabolomics to identify pneumococcal vaccine candidates
  36. The Choline-binding Protein PspC of Streptococcus pneumoniae Interacts with the C-terminal Heparin-binding Domain of Vitronectin
  37. Structural Reevaluation ofStreptococcus pneumoniaeLipoteichoic Acid and New Insights into Its Immunostimulatory Potency
  38. Lung dendritic cells facilitate extrapulmonary bacterial dissemination during pneumococcal pneumonia
  39. Microbial pathogens of diverse origin inhibit the terminal complement pathway: A common immune evasion strategy?
  40. Enolase of Streptococcus pneumoniae Binds Human Complement Inhibitor C4b-Binding Protein and Contributes to Complement Evasion
  41. Bacterial Abuse of Mammalian Extracellular Proteases during Tissue Invasion and Infection
  42. Streptococcus Pneumoniae Interference With Purinergic Signaling In Alveolar Epithelial Cells - Hints Towards A Direct Purine Receptor Interaction
  43. In Pulmonary Endothelial Cells Calcium Signaling By S. Pneumoniae Is Regulated By Calcium Influx From The Extracellular Space But Also By Calcium Release From Intracellular Stores
  44. Combat Pneumococcal Infections: Adhesins as Candidates for Protein- Based Vaccine Development
  45. Tumor Necrosis Factor Alpha Modulates the Dynamics of the Plasminogen-Mediated Early Interaction between Bifidobacterium animalis subsp.lactisand Human Enterocytes
  46. Characterization of Central Carbon Metabolism of Streptococcus pneumoniae by Isotopologue Profiling
  47. Streptococcus pneumoniae Stimulates a STING- and IFN Regulatory Factor 3-Dependent Type I IFN Production in Macrophages, which Regulates RANTES Production in Macrophages, Cocultured Alveolar Epithelial Cells, and Mouse Lungs
  48. Streptococcus pneumoniae induces exocytosis of Weibel-Palade bodies in pulmonary endothelial cells
  49. The NLRP3 Inflammasome Contributes to Brain Injury in Pneumococcal Meningitis and Is Activated through ATP-Dependent Lysosomal Cathepsin B Release
  50. Crystallization and preliminary X-ray diffraction analysis of a thioredoxin fromStreptococcus pneumoniae
  51. Relevance of Bifidobacterium animalis subsp. lactis Plasminogen Binding Activity in the Human Gastrointestinal Microenvironment
  52. Alpha-enolase of Streptococcus pneumoniae binds the human complement inhibitor C4-binding protein and mediates pneumococcal complement evasion
  53. Pneumococcal Adherence And Virulence Factor A (PAVA) Induces Endothelial CA2+-Signaling In Pulmonary Capillary Venules
  54. Streptococcus Pneumoniae Inhibits Adenosine-Triphosphate (ATP)-Mediated Calcium Release In Alveolar Epithelial Cells
  55. Streptococcus Pneumoniae Subtilisin-Like Serine Protease A Corrupted Pulmonary Epithelium By Inducing Alpha MSH
  56. Streptococcus pneumoniae Infection of Host Epithelial Cells via Polymeric Immunoglobulin Receptor Transiently Induces Calcium Release from Intracellular Stores
  57. Genomic organization, structure, regulation and pathogenic role of pilus constituents in major pathogenic Streptococci and Enterococci
  58. Krüppel-like Factor 2 terminiert die Streptococcus pneumoniae-induzierte pro-inflammatorischen Antwort in humanen bronchial Epithelzellen
  59. Mast Cells Increase Vascular Permeability by Heparin-Initiated Bradykinin Formation In Vivo
  60. Impact of Glutamine Transporters on Pneumococcal Fitness under Infection-Related Conditions
  61. Polymeric Immunoglobulin Receptor-mediated Invasion ofStreptococcus pneumoniaeinto Host Cells Requires a Coordinate Signaling of SRC Family of Protein-tyrosine Kinases, ERK, and c-Jun N-terminal Kinase
  62. Mechanism of complement regulator Factor H mediated pneumococcal uptake by human cells
  63. Complement Regulator Factor H Mediates a Two-step Uptake of Streptococcus pneumoniae by Human Cells
  64. PavB is a surface-exposed adhesin of Streptococcus pneumoniae contributing to nasopharyngeal colonization and airways infections
  65. Toll-Like Receptor Stimulation Enhances Phagocytosis and Intracellular Killing of Nonencapsulated and Encapsulated Streptococcus pneumoniae by Murine Microglia
  66. Pneumococcal association to platelets is mediated by soluble fibrin and supported by thrombospondin-1
  67. Surface-associated lipoprotein PpmA of Streptococcus pneumoniae is involved in colonization in a strain-specific manner
  68. Fibronectin stimulatesEscherichia coliphagocytosis by microglial cells
  69. Surface-Exposed Adherence Molecules of Streptococcus pneumoniae
  70. Integrin-linked kinase is required for vitronectin-mediated internalization of Streptococcus pneumoniae by host cells
  71. The complement fitness Factor H: Role in human diseases and for immune escape of pathogens, like pneumococci
  72. Complement evasion of Streptococcus pneumoniae: The factor H binding protein PspC acts as a potent complement inhibitor
  73. Phagocytosis of non-encapsulated and encapsulated Streptococcus pneumoniae by murine microglia is increased after stimulation with Toll-like receptors agonists
  74. The surface-associated elongation factor Tu is concealed for antibody binding on viable pneumococci and meningococci
  75. Fibrinolysis and bacteria
  76. Thrombospondin-1 promotes cellular adherence of Gram-positive pathogens via recognition of peptidoglycan
  77. Cytosolic Proteins Contribute to Surface Plasminogen Recruitment of Neisseria meningitidis
  78. Cell-specific Interleukin-15 and Interleukin-15 receptor subunit expression and regulation in pneumococcal pneumonia—Comparison to chlamydial lung infection
  79. The Host Immune Regulator Factor H Interacts via Two Contact Sites with the PspC Protein of Streptococcus pneumoniae and Mediates Adhesion to Host Epithelial Cells
  80. Cytosolic Proteins Contribute to Surface Plasminogen Recruitment of Neisseria meningitidis
  81. Fibrinolysis and host response in bacterial infections
  82. Adherence molecules of pathogenic pneumococci
  83. Streptococcus pneumoniae R6x induced p38 MAPK and JNK-mediated Caspase-dependent apoptosis in human endothelial cells
  84. The nine residue plasminogen-binding motif of the pneumococcal enolase is the major cofactor of plasmin-mediated degradation of extracellular matrix, dissolution of fibrin and transmigration
  85. Threat of infection: Microbes of high pathogenic potential – strategies for detection, control and eradication
  86. Cloning, characterization and DNA immunization of an Onchocerca volvulus glyceraldehyde-3-phosphate dehydrogenase (Ov-GAPDH)
  87. PavA of Streptococcus pneumoniae Modulates Adherence, Invasion, and Meningeal Inflammation
  88. Streptococcus pneumoniae-induced p38 MAPK-dependent Phosphorylation of RelA at the Interleukin-8 Promotor
  89. Plasmin(ogen)-binding α-Enolase from Streptococcus pneumoniae: Crystal Structure and Evaluation of Plasmin(ogen)-binding Sites
  90. The cell wall subproteome ofListeria monocytogenes
  91. Streptococcus pneumoniae-Induced Caspase 6-Dependent Apoptosis in Lung Epithelium
  92. Streptococcus pneumoniae induced caspase 6-deptendent apoptosis in lung epithelium
  93. Binding of α 2 -macroglobulin to GRAB (Protein G-related α 2 -macroglobulin-binding protein), an important virulence factor of group A streptococci, is mediated by two charged motifs in the ΔA region
  94. Nucleotide-binding Oligomerization Domain Proteins Are Innate Immune Receptors for Internalized Streptococcus pneumoniae
  95. Dual Roles of PspC, a Surface Protein of Streptococcus pneumoniae, in Binding Human Secretory IgA and Factor H
  96. Glyceraldehyde-3-Phosphate Dehydrogenase of Streptococcus pneumoniae Is a Surface-Displayed Plasminogen-Binding Protein
  97. Identification of a novel plasmin(ogen)-binding motif in surface displayed α-enolase of Streptococcus pneumoniae
  98. Molecular cloning of an α-enolase from the human filarial parasite Onchocerca volvulus that binds human plasminogen
  99. Species-specific binding of human secretory component to SpsA protein of Streptococcus pneumoniae via a hexapeptide motif
  100. The pavA gene of Streptococcus pneumoniae encodes a fibronectin-binding protein that is essential for virulence
  101. alpha-Enolase of Streptococcus pneumoniae is a plasmin(ogen)-binding protein displayed on the bacterial cell surface
  102. Response from Chhatwal and Hammerschmidt
  103. SpsA, a novel pneumococcal surface protein with specific binding to secretory Immunoglobulin A and secretory component
  104. Sialic acids of both the capsule and the sialylated lipooligosaccharide of Neisseria meningitis serogroup B are prerequisites for virulence of meningococci in the infant rat
  105. Capsule phase variation in Neisseria meningitidis serogroup B by slipped-strand mispairing in the polysialyltransferase gene (siaD): correlation with bacterial invasion and the outbreak of meningococcal disease
  106. The Influence of Capsulation and Lipooligosaccharide Structure on Neutrophil Adhesion Molecule Expression and Endothelial Injury by Neisseria meningitidis
  107. Molecular analysis of the biosynthesis pathway of the ?-2,8 polysialic acid capsule by Neisseria meningitidls serogroup B
  108. Contribution of genes from the capsule gene complex (cps) to lipooligosaccharide biosynthesis and serum resistance in Neisseria meningitidis
  109. The cell wall subproteome ofListeria monocytogenes
  110. Pathogenesis of Streptococcus pneumoniae infections:adaptive immunity, innate immunity, cell biology, virulence factors
  111. Streptococcus pneumoniae meningitis.