All Stories

  1. Evaluating genetic causes of azoospermia: What can we learn from a complex cellular structure and single-cell transcriptomics of the human testis?

    Article • Human Genetics, January 2020, Springer Science + Business Media

    Mr Kristian Almstrup

  2. A polygenic risk score suggests shared genetic architecture of voice break with early markers of pubertal onset in boys

    Article • The Journal of Clinical Endocrinology & Metabolism, January 2020, Endocrine Society

    Mr Kristian Almstrup

  3. Developmental origins of testicular germ cell tumours (TGCT)

    Article • European Urology Supplements, September 2019, Elsevier

    Mr Kristian Almstrup

  4. Identification of circulating small non-coding RNAs in relation to male subfertility and reproductive hormones

    Article • Molecular and Cellular Endocrinology, May 2019, Elsevier

    Mr Kristian Almstrup

  5. Medium-throughput Screening Assays for Assessment of Effects on Ca2+-Signaling and Acrosome Reaction in Human Sperm

    Article • Journal of Visualized Experiments, March 2019, MyJove Corporation

    Mr Kristian Almstrup

  6. Expression of the O-Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa

    Article • International Journal of Molecular Sciences, September 2018, MDPI AG

    Mr Kristian Almstrup

  7. Decrease in semen quality and Leydig cell function in infertile men: a longitudinal study

    Article • Human Reproduction, September 2018, Oxford University Press (OUP)

    Mr Kristian Almstrup

  8. Transcriptome analysis of the adult human Klinefelter testis and cellularity-matched controls reveals disturbed differentiation of Sertoli- and Leydig cells

    Article • Cell Death and Disease, May 2018, Springer Science + Business Media

    Mr Kristian Almstrup

  9. Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies

    Article • Human Molecular Genetics, January 2018, Oxford University Press (OUP)

    Mr Kristian Almstrup, Dr Stuart MacGowan

  10. The AMH genotype (rs10407022 T>G) is associated with circulating AMH levels in boys, but not in girls

    Article • Endocrine Connections, January 2018, Bioscientifica

    Mr Kristian Almstrup

  11. Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status

    Article • Human Reproduction, January 2018, Oxford University Press (OUP)

    Mr Kristian Almstrup

  12. Polymorphisms in JMJD1C are associated with pubertal onset in boys and reproductive function in men

    Article • Scientific Reports, December 2017, Nature

    Mr Kristian Almstrup

  13. Is the FSHR 2039A>G variant associated with susceptibility to testicular germ cell cancer?

    Article • Andrology, November 2017, Wiley

    Mr Kristian Almstrup

  14. Transcriptome profiling of fetal Klinefelter testis tissue reveals a possible involvement of long non-coding RNAs in gonocyte maturation

    Article • Human Molecular Genetics, November 2017, Oxford University Press (OUP)

    Mr Kristian Almstrup

  15. Differential impact of genetic loci on age at thelarche and menarche in healthy girls

    Article • The Journal of Clinical Endocrinology & Metabolism, October 2017, Endocrine Society

    Mr Kristian Almstrup

  16. Possible involvement of the glucocorticoid receptor (NR3C1) and selected NR3C1 gene variants in regulation of human testicular function

    Article • Andrology, October 2017, Wiley

    Mr Kristian Almstrup

  17. EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner

    Article • Endocrine Connections, September 2017, Bioscientifica

    Mr Kristian Almstrup

  18. Genetic Variation of Follicle-Stimulating Hormone Action Is Associated With Age at Testicular Growth in Boys

    Article • The Journal of Clinical Endocrinology & Metabolism, February 2017, Endocrine Society

    Mr Kristian Almstrup, Professor Katharina Maria Main

  19. Validation of image cytometry for sperm concentration measurement: Comparison with manual counting of 4010 human semen samples

    Article • Clinica Chimica Acta, February 2017, Elsevier

    Mr Kristian Almstrup

  20. Dynamic GnRH and hCG testing: establishment of new diagnostic reference levels

    Article • European Journal of Endocrinology, January 2017, Bioscientifica

    Mr Kristian Almstrup

  21. Convolutional Neural Networks for Segmentation and Object Detection of Human Semen

    Article • January 2017, Springer Science + Business Media

    Mr Kristian Almstrup

  22. Selection of high quality spermatozoa may be promoted by activated vitamin D in the woman

    Article • The Journal of Clinical Endocrinology & Metabolism, December 2016, Endocrine Society

    Mr Kristian Almstrup, Mr Anders AR Rehfeld, Anders Berg

  23. Differences in global DNA methylation of testicular seminoma are not associated with changes in histone modifications, clinical prognosis, BRAF mutations or gene expression

    Article • Cancer Genetics, November 2016, Elsevier

    Mr Kristian Almstrup

  24. Erratum: Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood

    Article • Scientific Reports, August 2016, Nature

    Mr Kristian Almstrup

  25. Genetic Variations in FSH Action Affect Sex Hormone Levels and Breast Tissue Size in Infant Girls: A Pilot Study

    Article • The Journal of Clinical Endocrinology & Metabolism, August 2016, Endocrine Society

    Mr Kristian Almstrup, Professor Katharina Maria Main

  26. Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood

    Article • Scientific Reports, June 2016, Nature

    Mr Kristian Almstrup

  27. Circulating MKRN3 Levels Decline During Puberty in Healthy Boys

    Article • The Journal of Clinical Endocrinology & Metabolism, June 2016, Endocrine Society

    Mr Kristian Almstrup

  28. Genetic variations altering FSH action affect circulating hormone levels as well as follicle growth in healthy peripubertal girls

    Article • Human Reproduction, February 2016, Oxford University Press (OUP)

    Mr Kristian Almstrup

  29. Diagnostic markers for germ cell neoplasms: from placental-like alkaline phosphatase to micro-RNAs

    Article • Folia Histochemica et Cytobiologica, October 2015, VM Media SP. zo.o VM Group SK

    Mr Kristian Almstrup

  30. Cell context-specific expression of primary cilia in the human testis and ciliary coordination of Hedgehog signalling in mouse Leydig cells

    Article • Scientific Reports, May 2015, Nature

    Mr Kristian Almstrup

  31. Circulating MKRN3 Levels Decline Prior to Pubertal Onset and Through Puberty: A Longitudinal Study of Healthy Girls

    Article • The Journal of Clinical Endocrinology & Metabolism, May 2015, Endocrine Society

    Mr Kristian Almstrup

  32. Involvement of epigenetic modifiers in the pathogenesis of testicular dysgenesis and germ cell cancer

    Article • BioMolecular Concepts, January 2015, De Gruyter

    Mr Kristian Almstrup

  33. Increasing international efforts to understand and conquer testicular germ cell cancer

    Article • Andrology, January 2015, Wiley

    Mr Kristian Almstrup

  34. Screening for carcinoma in situ in the contralateral testicle in patients with testicular cancer: a population-based study

    Article • Annals of Oncology, December 2014, Oxford University Press (OUP)

    Mr Kristian Almstrup

  35. A survey of etiologic hypotheses among testicular cancer researchers

    Article • Andrology, December 2014, Wiley

    Mr Kristian Almstrup

  36. Perinatal exposure to mixtures of anti-androgenic chemicals causes proliferative lesions in rat prostate

    Article • The Prostate, October 2014, Wiley

    Mr Kristian Almstrup

  37. Pubertal Onset in Girls is Strongly Influenced by Genetic Variation Affecting FSH Action

    Article • Scientific Reports, September 2014, Nature

    Mr Kristian Almstrup

  38. Possible fetal determinants of male infertility

    Article • Nature Reviews Endocrinology, June 2014, Nature

    Mr Kristian Almstrup

  39. Screening for carcinoma in situ (CIS) testis and occurrence of metachronous germ cell cancer (mGCC).

    Article • Journal of Clinical Oncology, May 2014, American Society of Clinical Oncology (ASCO)

    Mr Kristian Almstrup

  40. Direct action of endocrine disrupting chemicals on human sperm

    Article • EMBO Reports, May 2014, EMBO

    Mr Kristian Almstrup, Mr Anders AR Rehfeld

  41. Syncytin-1 and its receptor is present in human gametes

    Article • Journal of Assisted Reproduction and Genetics, April 2014, Springer Science + Business Media

    Mr Kristian Almstrup

  42. A Tortoiseshell Male Cat: Chromosome Analysis and Histologic Examination of the Testis

    Article • Cytogenetic and Genome Research, December 2013, Karger Publishers

    Mr Kristian Almstrup

  43. Phenotypic characterisation of immune cell infiltrates in testicular germ cell neoplasia

    Article • Journal of Reproductive Immunology, December 2013, Elsevier

    Mr Kristian Almstrup

  44. Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis

    Article • British Journal of Cancer, November 2013, Nature

    Mr Kristian Almstrup

  45. FSHB-211 and FSHR 2039 are associated with serum levels of follicle-stimulating hormone and antimüllerian hormone in healthy girls: a longitudinal cohort study

    Article • Fertility and Sterility, October 2013, Elsevier

    Mr Kristian Almstrup

  46. Image cytometer method for automated assessment of human spermatozoa concentration

    Article • Andrology, April 2013, Wiley

    Mr Kristian Almstrup

  47. FSHB−211 andFSHR2039 polymorphisms are associated with serum levels of FSH, AMH and age of pubertal onset in 78 healthy girls: a longitudinal cohort study

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Professor Richard A Anderson, Mr Kristian Almstrup

  48. Endocrine disruptors in seminal fluid: bisphenol A, triclosan and benzophenone-3

    Article • Endocrine Abstracts, April 2013, Bioscientifica

    Mr Kristian Almstrup

  49. Androgen Receptor CAG Repeat Length Is Associated With Body Fat and Serum SHBG in Boys: A Prospective Cohort Study

    Article • The Journal of Clinical Endocrinology & Metabolism, March 2013, Endocrine Society

    Mr Kristian Almstrup

  50. Dysregulation of the mitosis-meiosis switch in testicular carcinoma in situ

    Article • The Journal of Pathology, February 2013, Wiley

    Mr Kristian Almstrup

  51. Transcriptome profiling of mice testes following low dose irradiation

    Article • Reproductive Biology and Endocrinology, January 2013, Springer Science + Business Media

    Mr Kristian Almstrup

  52. Epigenetic features of testicular germ cell tumours in relation to epigenetic characteristics of foetal germ cells

    Article • The International Journal of Developmental Biology, January 2013, UBC Press

    Mr Kristian Almstrup

  53. Testicular Dysgenesis Syndrome and Carcinoma In Situ Testis

    Article • September 2012, Springer Science + Business Media

    Mr Kristian Almstrup

  54. The Testis in Childhood Between Birth and Puberty

    Article • September 2012, Springer Science + Business Media

    Mr Kristian Almstrup

  55. Heterogeneity of chromatin modifications in testicular spermatocytic seminoma point toward an epigenetically unstable phenotype

    Article • Cancer Genetics, September 2012, Elsevier

    Mr Kristian Almstrup

  56. MicroRNA expression profiling of carcinoma in situ cells of the testis

    Article • March 2012, Bioscientifica

    Mr Kristian Almstrup

  57. Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes

    Article • PLoS Genetics, February 2012, PLOS

    Mr Kristian Almstrup

  58. Human semen quality in the new millennium: a prospective cross-sectional population-based study of 4867 men

    Article • BMJ Open, January 2012, BMJ

    Mr Kristian Almstrup

  59. 18 Perinatal origin of testicular germ cell cancer: Possible involvement of developmental reprogramming

    Article • November 2011, De Gruyter

    Mr Kristian Almstrup

  60. Perinatal Programming

    Article • November 2011, De Gruyter

    Mr Kristian Almstrup

  61. Commentary: Sperm Counts, Data Responsibility, and Good Scientific Practice

    Article • Epidemiology, September 2011, Wolters Kluwer Health

    Mr Kristian Almstrup

  62. Screening of subfertile men for testicular carcinoma in situ by an automated image analysis-based cytological test of the ejaculate

    Article • International Journal of Andrology, June 2011, Wiley

    Mr Kristian Almstrup

  63. Clinical and biological parameters in 166 boys, adolescents and adults with nonmosaic Klinefelter syndrome: a Copenhagen experience

    Article • Acta Paediatrica, March 2011, Wiley

    Mr Kristian Almstrup

  64. A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples

    Article • Andrologia, February 2011, Wiley

    Mr Kristian Almstrup

  65. Germ Cell Cancer, Testicular Dysgenesis Syndrome and Epigenetics

    Article • October 2010, Springer Science + Business Media

    Mr Kristian Almstrup

  66. Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cells

    Article • British Journal of Cancer, September 2010, Nature

    Mr Kristian Almstrup

  67. Lipoprotein lipase and endothelial lipase in human testis and in germ cell neoplasms

    Article • International Journal of Andrology, September 2009, Wiley

    Mr Kristian Almstrup

  68. Analysis of Gene Expression Profiles of Microdissected Cell Populations Indicates that Testicular Carcinoma In situ Is an Arrested Gonocyte

    Article • Cancer Research, June 2009, American Association for Cancer Research (AACR)

    Mr Kristian Almstrup

  69. Re: Niels J. van Casteren, Hans Stoop, Gert R. Dohle, Ronald de Wit, J. Wolter Oosterhuis, Leendert H.J. Looijenga. Noninvasive Detection of Testicular Carcinoma In Situ in Semen Using OCT3/4. Eur Urol 2008;54:153–60

    Article • European Urology, April 2009, Elsevier

    Mr Kristian Almstrup

  70. Gene expression profiles of mouse spermatogenesis during recovery from irradiation

    Article • Reproductive Biology and Endocrinology, January 2009, Springer Science + Business Media

    Mr Kristian Almstrup

  71. Origin of pluripotent germ cell tumours: The role of microenvironment during embryonic development

    Article • Molecular and Cellular Endocrinology, June 2008, Elsevier

    Mr Kristian Almstrup

  72. Improved gene expression signature of testicular carcinoma in situ

    Article • International Journal of Andrology, August 2007, Wiley

    Mr Kristian Almstrup

  73. Current approaches for detection of carcinoma in situ testis

    Article • International Journal of Andrology, August 2007, Wiley

    Mr Kristian Almstrup

  74. CDH1 (E-cadherin) in testicular germ cell neoplasia: suppressed translation of mRNA in pre-invasive carcinoma in situ but increased protein levels in advanced tumours

    Article • Apmis, August 2006, Wiley

    Mr Kristian Almstrup

  75. Estrogenic Effect of Soy Isoflavones on Mammary Gland Morphogenesis and Gene Expression Profile

    Article • Toxicological Sciences, June 2006, Oxford University Press (OUP)

    Mr Kristian Almstrup

  76. Identity of M2A (D2-40) antigen and gp36 (Aggrus, T1A-2, podoplanin) in human developing testis, testicular carcinoma in situ and germ-cell tumours

    Article • Virchows Archiv, May 2006, Springer Science + Business Media

    Mr Kristian Almstrup

  77. From embryonic stem cells to testicular germ cell cancer - should we be concerned?

    Article • International Journal of Andrology, February 2006, Wiley

    Mr Kristian Almstrup

  78. Dysfunction of the mitotic:meiotic switch as a potential cause of neoplastic conversion of primordial germ cells

    Article • International Journal of Andrology, February 2006, Wiley

    Mr Kristian Almstrup

  79. Mouse models for genes involved in impaired spermatogenesis

    Article • International Journal of Andrology, February 2006, Wiley

    Mr Kristian Almstrup

  80. Identification and expression profiling of 10 novel spermatid expressed CYPT genes

    Article • Molecular Reproduction and Development, January 2006, Wiley

    Mr Kristian Almstrup

  81. Stem cell pluripotency factor NANOG is expressed in human fetal gonocytes, testicular carcinoma in situ and germ cell tumours

    Article • Histopathology, July 2005, Wiley

    Mr Kristian Almstrup

  82. Genome-wide gene expression profiling of testicular carcinoma in situ progression into overt tumours

    Article • British Journal of Cancer, April 2005, Nature

    Mr Kristian Almstrup

  83. Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ

    Article • Cell and Tissue Research, April 2005, Springer Science + Business Media

    Mr Kristian Almstrup

  84. A subfertile patient diagnosed with testicular carcinoma in situ by immunocytological staining for AP-2  in semen samples: Case report

    Article • Human Reproduction, February 2005, Oxford University Press (OUP)

    Mr Kristian Almstrup

  85. Transcription Factor AP-2  Is a Developmentally Regulated Marker of Testicular Carcinoma In situ and Germ Cell Tumors

    Article • Clinical Cancer Research, December 2004, American Association for Cancer Research (AACR)

    Mr Kristian Almstrup

  86. Embryonic Stem Cell-Like Features of Testicular Carcinoma in Situ Revealed by Genome-Wide Gene Expression Profiling

    Article • Cancer Research, July 2004, American Association for Cancer Research (AACR)

    Mr Kristian Almstrup

  87. Identification of genes differentially expressed in testes containing carcinoma in situ

    Article • Molecular Human Reproduction, March 2004, Oxford University Press (OUP)

    Mr Kristian Almstrup

  88. Analysis of Cell-Type-Specific Gene Expression During Mouse Spermatogenesis

    Article • Biology of Reproduction, February 2004, Society for the Study of Reproduction

    Mr Kristian Almstrup

  89. Dual Effects of Phytoestrogens Result in U-Shaped Dose-Response Curves

    Article • Environmental Health Perspectives, June 2002, Environmental Health Perspectives

    Mr Kristian Almstrup

  90. A Fast Method for Measurement of Branching Enzyme Activity Using a Thin-Layer Chromatography-Based Phosphorylase a Stimulation Assay

    Article • Analytical Biochemistry, November 2000, Elsevier

    Mr Kristian Almstrup