All Stories

  1. Long-read sequencing of primate testis and human sperm allows identification of recombination events in individuals

    Article • Nature Communications, November 2025, Springer Science + Business Media

    Mr Kristian Almstrup, Dr Sandra S Laurentino

  2. Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

    Article • Andrology, November 2025, Wiley

    Dr Sandra S Laurentino

  3. Functional and clinical insights into nuclear receptor variants for advancing precision diagnostics in male infertility

    Article • EBioMedicine, September 2025, Elsevier

    Dr Sandra S Laurentino

  4. The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis

    Article • eLife, October 2024, eLife

    Dr Sandra S Laurentino

  5. Integration of long-read sequencing, DNA methylation and gene expression reveals heterogeneity in Y chromosome segment lengths in phenotypic males with 46,XX testicular disorder/difference of sex development

    Article • Biology of Sex Differences, October 2024, Springer Science + Business Media

    Dr Sandra S Laurentino

  6. Insights into gene conversion and crossing-over processes from long-read sequencing of human, chimpanzee and gorilla testes and sperm

    Article • July 2024, Cold Spring Harbor Laboratory Press

    Dr Sandra S Laurentino

  7. Genome-wide DNA methylation changes in human spermatogenesis

    Article • The American Journal of Human Genetics, June 2024, Elsevier

    Dr Sandra S Laurentino

  8. Genome-wide DNA methylation changes in human spermatogenesis

    Article • November 2023, Cold Spring Harbor Laboratory Press

    Dr Sandra S Laurentino

  9. OGRE: calculate, visualize, and analyze overlap between genomic input regions and public annotations

    Article • BMC Bioinformatics, July 2023, Springer Science + Business Media

    Dr Sandra S Laurentino

  10. Balancing the scales: the interplay of diet, exercise, GLP-1 receptor agonists, and obesity in shaping male reproductive health

    Article • Human Reproduction, June 2023, Oxford University Press (OUP)

    Dr Sandra S Laurentino

  11. WWC2 expression in the testis: Implications for spermatogenesis and male fertility

    Article • The FASEB Journal, April 2023, Wiley

    Dr Sandra S Laurentino

  12. Testicular Architecture of Men with 46,XX Testicular Disorders of Sex Development

    Article • Sexual Development, January 2023, Karger Publishers

    Dr Sandra S Laurentino

  13. Transcriptome analyses in infertile men reveal germ cell–specific expression and splicing patterns

    Article • Life Science Alliance, November 2022, Life Science Alliance, LLC

    Dr Sandra S Laurentino

  14. Male reproductive aging: can men with oligospermia become azoospermic over time?

    Article • International Journal of Impotence Research, October 2022, Springer Science + Business Media

    Dr Sandra S Laurentino

  15. Stage-specific gene and transcript dynamics in human male germ cells

    Article • March 2022, Cold Spring Harbor Laboratory Press

    Dr Sandra S Laurentino

  16. The conserved genetic program of male germ cells uncovers ancient regulators of human spermatogenesis

    Article • March 2022, Cold Spring Harbor Laboratory Press

    Dr Sandra S Laurentino

  17. Single-cell RNA-seq unravels alterations of the human spermatogonial stem cell compartment in patients with impaired spermatogenesis

    Article • Cell Reports Medicine, September 2021, Elsevier

    Dr Sandra S Laurentino

  18. Whole-genome methylation analysis of testicular germ cells from cryptozoospermic men points to recurrent and functionally relevant DNA methylation changes

    Article • Clinical Epigenetics, August 2021, Springer Science + Business Media

    Dr Sandra S Laurentino

  19. Healthy ageing and spermatogenesis

    Article • Reproduction, April 2021, Bioscientifica

    Dr Sandra S Laurentino

  20. EGR4-dependent decrease of UTF1 is associated with failure to reserve spermatogonial stem cells in infertile men

    Article • February 2021, Cold Spring Harbor Laboratory Press

    Dr Sandra S Laurentino

  21. The role of gonadotropins in testicular and adrenal androgen biosynthesis pathways—Insights from males with congenital hypogonadotropic hypogonadism on hCG/rFSH and on testosterone replacement

    Article • Clinical Endocrinology, September 2020, Wiley

    Julia Rohayem, Dr Sandra S Laurentino

  22. A germ cell‐specific ageing pattern in otherwise healthy men

    Article • Aging Cell, September 2020, Wiley

    Dr Sandra S Laurentino

  23. The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis

    Article • Clinical Epigenetics, May 2020, Springer Science + Business Media

    Dr Sandra S Laurentino

  24. wg-blimp: an end-to-end analysis pipeline for whole genome bisulfite sequencing data

    Article • BMC Bioinformatics, May 2020, Springer Science + Business Media

    Dr Sandra S Laurentino

  25. The sperm epigenome does not display recurrent epimutations in patients with severely impaired spermatogenesis

    Article • February 2020, Cold Spring Harbor Laboratory Press

    Dr Sandra S Laurentino

  26. Molecular Aging Markers in Patients with Klinefelter Syndrome

    Article • Aging and Disease, January 2020, Aging and Disease

    Julia Rohayem, Dr Sandra S Laurentino

  27. wg-blimp: an end-to-end analysis pipeline for whole genome bisulfite sequencing data

    Article • November 2019, Cold Spring Harbor Laboratory Press

    Dr Sandra S Laurentino

  28. Healthy ageing men have normal reproductive function but display germline-specific molecular changes

    Article • September 2019, Cold Spring Harbor Laboratory Press

    Dr Sandra S Laurentino

  29. High-resolution analysis of germ cells from men with sex chromosomal aneuploidies reveals normal transcriptome but impaired imprinting

    Article • Clinical Epigenetics, August 2019, Springer Science + Business Media

    Dr Sandra S Laurentino

  30. De novo methylation in male germ cells of the common marmoset monkey occurs during postnatal development and is maintained in vitro

    Article • Epigenetics, October 2016, Taylor & Francis

    Dr Sandra S Laurentino

  31. The human RHOX gene cluster: target genes and functional analysis of gene variants in infertile men

    Article • Human Molecular Genetics, September 2016, Oxford University Press (OUP)

    Dr Sandra S Laurentino

  32. On the origin of sperm epigenetic heterogeneity

    Article • Reproduction, February 2016, Bioscientifica

    Dr Sandra S Laurentino

  33. Epigenetic germline mosaicism in infertile men

    Article • Human Molecular Genetics, October 2014, Oxford University Press (OUP)

    Dr Sandra S Laurentino

  34. Structural variants of sex steroid hormone receptors in the testis: from molecular biology to physiological roles

    Article • OA Biotechnology, December 2012, Open Access Publishing London

    Dr Sandra S Laurentino

  35. Identification of androgen receptor variants in testis from humans and other vertebrates

    Article • Andrologia, June 2012, Wiley

    Dr Sandra S Laurentino

  36. Effect of insulin deprivation on metabolism and metabolism-associated gene transcript levels of in vitro cultured human Sertoli cells

    Article • Biochimica et Biophysica Acta (BBA) - General Subjects, February 2012, Elsevier

    Dr Sandra S Laurentino

  37. Regucalcin, a calcium-binding protein with a role in male reproduction?

    Article • Molecular Human Reproduction, November 2011, Oxford University Press (OUP)

    Dr Sandra S Laurentino

  38. Apoptosis-inhibitor Aven is downregulated in defective spermatogenesis and a novel estrogen target gene in mammalian testis

    Article • Fertility and Sterility, September 2011, Elsevier

    Dr Sandra S Laurentino

  39. Regucalcin is broadly expressed in male reproductive tissues and is a new androgen-target gene in mammalian testis

    Article • Reproduction, June 2011, Bioscientifica

    Dr Sandra S Laurentino

  40. Estrogen Receptors α and β in Human Testis: Both Isoforms are Expressed

    Article • Systems Biology in Reproductive Medicine, August 2009, Taylor & Francis

    Dr Sandra S Laurentino

  41. Estrogen Receptors α and β in Human Testis: Both Isoforms are Expressed

    Article • Systems Biology in Reproductive Medicine, January 2009, Taylor & Francis

    Dr Sandra S Laurentino