All Stories

  1. Metabolomic Signatures of Biotrauma Associated with Mortality in ICU Patients Requiring Invasive Mechanical Ventilation and ECMO
  2. Risk Phenotyping Before Graft Implantation: FTIR Spectroscopy and Machine Learning for Complementary Risk Stratification in Kidney Transplantation
  3. Day-Zero Serum FTIR Spectroscopy Identifies a Biochemical Signature Associated with Functional Pancreas Graft Dysfunction After Simultaneous Pancreas–Kidney Transplantation
  4. Prediction of Chronic Kidney Disease Based on Simulated Serum Analysis by Vibrational Spectroscopy
  5. Traditional Versus Intentionally Created Severity Scores for COVID-19 Prognosis: Evidence from a Portuguese Cohort
  6. Blood biomarker trajectories in ICU-directed prediction models – A scoping review
  7. Pre-Transplant Serum FTIRS Signatures as Predictive Biomarkers of Early Transient Pancreatic Graft Dysfunction in Simultaneous Pancreas-Kidney Transplantation
  8. Rejection-Focused Precision Medicine in Kidney Transplantation: Biology, Biomarkers, and Artificial Intelligence
  9. Machine Learning-Assisted FTIR Spectroscopy Analysis of Kidney Preservation Fluids for Delayed Graft Function Risk Stratification
  10. FT-MIR Spectroscopy Coupled with Machine Learning for the Identification of Antimicrobial Spectral Markers in Marine Drug Discovery
  11. Comparison of Mid and Near-Infrared Spectroscopy to Predict Creatinine, Urea and Albumin in Serum Samples as Biomarkers of Renal Function
  12. Rapid FTIR Spectral Fingerprinting of Kidney Allograft Perfusion Fluids Distinguishes DCD from DBD Donors: A Pilot Machine Learning Study
  13. Multiplex Targeted Proteomic Analysis of Cytokine Ratios for ICU Mortality in Severe COVID-19
  14. Analyzing Heart Rate Variability for COVID-19 ICU Mortality Prediction Using Continuous Signal Processing Techniques
  15. Predictive Models of Patient Severity in Intensive Care Units Based on Serum Cytokine Profiles: Advancing Rapid Analysis
  16. Cytokine-Based Insights into Bloodstream Infections and Bacterial Gram Typing in ICU COVID-19 Patients
  17. Integration of FTIR Spectroscopy and Machine Learning for Kidney Allograft Rejection: A Complementary Diagnostic Tool
  18. Chitosan Nanoparticles for Enhanced Immune Response and Delivery of Multi-Epitope Helicobacter pylori Vaccines in a BALB/c Mouse Model
  19. Comparison of two metabolomics-platforms to discover biomarkers in critically ill patients from serum analysis
  20. Early Mortality Prediction in Intensive Care Unit Patients Based on Serum Metabolomic Fingerprint
  21. Analysis of six consecutive waves of ICU-admitted COVID-19 patients: key findings and insights from a Portuguese population
  22. Impact of neutrophil‐activating protein conservation on diagnostic tests and vaccine design
  23. Discovery of Delirium Biomarkers through Minimally Invasive Serum Molecular Fingerprinting
  24. A new methodology for a rapid and high‐throughput comparison of molecular profiles and biological activity of phytoextracts
  25. Bridging the gap between target-based and phenotypic-based drug discovery
  26. Enhancing Bioactive Compound Classification through the Synergy of Fourier-Transform Infrared Spectroscopy and Advanced Machine Learning Methods
  27. Simplifying Data Analysis in Biomedical Research: An Automated, User-Friendly Tool
  28. Enhancing Bioactive Compound Classification through the Synergy of Fourier-Transform Infrared Spectroscopy and Advanced Machine Learning Methods
  29. Predicting Cellular Rejection of Renal Allograft Based on the Serum Proteomic Fingerprint
  30. Exosomes and microvesicles in kidney transplantation: the long road from trash to gold
  31. The Characteristics and Laboratory Findings of SARS-CoV-2 Infected Patients during the First Three COVID-19 Waves in Portugal—A Retrospective Single-Center Study
  32. Blood molecular profile to predict genotoxicity from exposure to antineoplastic drugs
  33. A new methodology for a rapid and high-throughput comparison of molecular profiles and biological activity of phytoextracts
  34. Alternative Serum Biomarkers of Bacteraemia for Intensive Care Unit Patients
  35. Comparison of Analytical Methods Of Serum Untargeted Metabolomics
  36. The Impact of the Serum Extraction Protocol on Metabolomic Profiling Using UPLC-MS/MS and FTIR Spectroscopy
  37. Label-free discrimination of T and B lymphocyte activation based on vibrational spectroscopy – A machine learning approach
  38. Quality Monitoring of Biodiesel and Diesel/Biodiesel Blends: A Comparison between Benchtop FT-NIR versus a Portable Miniaturized NIR Spectroscopic Analysis
  39. Epigenetic and Drug Response Modulation of Epigalocaten-In-3-Gallate in Staphylococcus aureus with Divergent Resistance Phenotypes
  40. Plasma versus Serum Analysis by FTIR Spectroscopy to Capture the Human Physiological State
  41. Antimicrobial evaluation of the Cynara cardunculus extract in Helicobacter pylori cells using mid-infrared spectroscopy and chemometric methods
  42. Proteomics for Biomarker Discovery for Diagnosis and Prognosis of Kidney Transplantation Rejection
  43. Ovine Model as a Temporomandibular Disc Substitute: Characterisation and the Outcomes of Freezing Storage
  44. Antigenic and conserved peptides from diverse Helicobacter pylori antigens
  45. Infection Biomarkers Based on Metabolomics
  46. Development of a biocompatible hydrogel based on native temporomandibular joint extracellular matrix powder
  47. Fast identification of off‐target liabilities in early antibiotic discovery with Fourier‐transform infrared spectroscopy
  48. A new method to predict genotoxic effects based on serum molecular profile
  49. Technologies for High-Throughput Identification of Antibiotic Mechanism of Action
  50. VARIABILITY OF NEUTROPHIL-ACTIVATING PROTEIN AMONG HELICOBACTER PYLORI STRAINS
  51. Comparison of partial least squares‐discriminant analysis and soft independent modeling of class analogy methods for classification of Saccharomyces cerevisiae cells based on mid‐infrared spectroscopy
  52. Simultaneous elucidation of antibiotic mechanism of action and potency with high-throughput Fourier-transform infrared (FTIR) spectroscopy and machine learning
  53. Potential of FTIR-Spectroscopy for Drugs Screening against Helicobacter pylori
  54. Discriminating B and T-lymphocyte from its molecular profile acquired in a label-free and high-throughput method
  55. FTIR spectroscopy applications for biomedicine
  56. A Simple, Label-Free, and High-Throughput Method to Evaluate the Epigallocatechin-3-Gallate Impact in Plasma Molecular Profile
  57. Metabolic Fingerprinting with Fourier-Transform Infrared (FTIR) Spectroscopy: Towards a High-Throughput Screening Assay for Antibiotic Discovery and Mechanism-of-Action Elucidation
  58. A phenotypic screening bioassay forEscherichia colistress and antibiotic responses based on Fourier‐transform infrared (FTIR) spectroscopy and multivariate analysis
  59. Antibiotic Discovery: Where Have We Come from, Where Do We Go?
  60. Characterization of gastric cells infection by diverse Helicobacter pylori strains through Fourier-transform infrared spectroscopy
  61. Assessing the molecular fingerprint of T lymphocyte activation
  62. Spectral Biomarkers of Genotoxicity from Methanol Extracts of Blood
  63. Impact of the solvent extraction method on the plasma metabolome profile
  64. Classification of recombinant Saccharomyces cerevisiae cells using PLS-DA modelling based on MIR spectroscopy
  65. Effect of culturing human embryos in group on the composition of spent culture media
  66. Towards an automated statistical workflow for biomarker screening in Fourier-transform infrared spectroscopy
  67. Impact of the human mesenchymal stem cells donor on conditional medium composition
  68. Effect of consumption of green tea extracts on the plasma molecular signature
  69. Helicobacter pylori Persistence Throughout the Host Life as a High Risk of Peptic Ulcers, Gastric Cancer and MALT Lymphoma
  70. Determination of Cell Abundances and Paralytic Shellfish Toxins in Cultures of the Dinoflagellate Gymnodinium catenatum by Fourier Transform Near Infrared Spectroscopy
  71. Assessing plasmid bioprocess reproducibility and C-source uptake stage through multivariate analysis of offline and online data
  72. Comparative analysis of different transformed Saccharomyces cerevisiae strains based on high-throughput Fourier transform infrared spectroscopy
  73. High-throughput FTIR-based bioprocess analysis of recombinant cyprosin production
  74. Optimization of a bioassay to evaluate Escherichia coli stress responses
  75. Biopharmaceuticals process monitoring based on infrared spectroscopy according to Quality by Design
  76. High-throughput bioassay for mechanism of action determination of antibacterial drugs
  77. Mid-infrared spectroscopy: A groundbreaking tool for monitoring mammalian cells processes
  78. Does Nonlinear Modeling Play a Role in Plasmid Bioprocess Monitoring Using Fourier Transform Infrared Spectra?
  79. Metabolic profiling of recombinantEscherichia colicultivations based on high-throughput FT-MIR spectroscopic analysis
  80. Monitoring theex-vivoexpansion of human mesenchymal stem/stromal cells in xeno-free microcarrier-based reactor systems by MIR spectroscopy
  81. A comprehensive high-throughput FTIR spectroscopy-based method for evaluating the transfection event: estimating the transfection efficiency and extracting associated metabolic responses
  82. In Situ Near-Infrared (NIR) versus High-Throughput Mid-Infrared (MIR) Spectroscopy to Monitor Biopharmaceutical Production
  83. Molecular fingerprint of human gastric cell line infected by Helicobacter pylori
  84. Development of a high-throughput monitoring technique of bacteria photodynamic inactivation
  85. Process Analytical Technologies in Biopharmaceutical Process Development
  86. In situ near infrared spectroscopy monitoring of cyprosin production by recombinant Saccharomyces cerevisiae strains
  87. Kinetic modeling of plasmid bioproduction in Escherichia coli DH5α cultures over different carbon-source compositions
  88. In situNIR spectroscopy monitoring of plasmid production processes: effect of producing strain, medium composition and the cultivation strategy
  89. Real-time plasmid monitoring of batch and fed-batch Escherichia coli cultures by NIR spectroscopy
  90. High-throughput analysis of the plasmid bioproduction process in Escherichia coli by FTIR spectroscopy
  91. Development and characterization of a new plasmid delivery system based on chitosan–sodium deoxycholate nanoparticles
  92. The importance of Helicobacter pylori's genetic variability for the construction of an efficient vaccine
  93. Modelling, monitoring and control of plasmid bioproduction in Escherichia coli cultures
  94. Protein and DNA nanoparticulate multiantigenic vaccines against H. pylori: In vivo evaluation
  95. A Nonionic Porphyrin as a Noninterfering DNA Antibacterial Agent
  96. Use of chemometrics in the selection of a Saccharomyces cerevisiae expression system for recombinant cyprosin B production
  97. Antigenic Diversity Among Portuguese Clinical Isolates of Helicobacter pylori
  98. Biodegradable nanoparticles of alginate and chitosan as non-viral DNA oral delivery system
  99. Monitoring bacterial processes by Fourier transform infrared spectroscopy: Helicobacter pylori drug inactivation and plasmid bioproduction in recombinant Escherichia coli cultures
  100. Optimization of the culture medium composition using response surface methodology for new recombinant cyprosin B production in bioreactor for cheese production
  101. A novel multifunctional DNA vaccine expresses conserved and immunogenic fragments of six Helicobacter pylori proteins
  102. The carbon-source on the efficiency of plasmid production in high density cultures of Escherichia coli
  103. Influence of tryptophan tags on the purification of cutinase, secreted by a recombinant Saccharomyces cerevisiae, using cationic expanded bed adsorption and hydrophobic interaction chromatography
  104. Prediction of retention time of cutinases tagged with hydrophobic peptides in hydrophobic interaction chromatography
  105. A flow injection analysis system for on‐line monitoring of cutinase activity at outlet of an expanded bed adsorption column almost in real time
  106. Micro-analytical GO/HRP bioreactor for glucose determination and bioprocess monitoring
  107. Integration of the production and the purification processes of cutinase secreted by a recombinant Saccharomyces cerevisiae SU50 strain
  108. Recombinant Saccharomyces cerevisiae strain triggers acetate production to fuel biosynthetic pathways
  109. Pressure-tuning FTIR Spectroscopy: Applications to Biomedical Research and Diagnosis
  110. Towards a cost effective strategy for cutinase production by a recombinant Saccharomyces cerevisiae: strain physiological aspects
  111. Integration of production and aqueous two-phase systems extraction of extracellular cutinase fusion proteins
  112. Development of a Fed-Batch Cultivation Strategy for the Enhanced production and Secretion of Cutinase by a Recombinant Saccharomyces cerevisiae SU50 Strain
  113. Development of a Fed-Batch Cultivation Strategy for the Enhanced Production and Secretion of Cutinase by a Recombinant Saccharomyces cerevisiae SU50 Strain
  114. Effect of Saccharomyces cerevisiae fermentation conditions on expanded bed adsorption of heterologous cutinase
  115. Optimisation of culture conditions and characterisation of cutinase produced by recombinant Saccharomyces cerevisiae
  116. Production of wild-type and peptide fusion cutinases by recombinantSaccharomyces cerevisiae MM01 strains
  117. Effect of pre-fermentation on the production of cutinase by a recombinant Saccharomyces cerevisiae