All Stories

  1. Multivalent interaction induces phase separation and formation of more toxic aggregates of α‐syn in a yeast model of Parkinson's disease

    Article • Protein Science, August 2025, Wiley

    Krishnananda Chattopadhyay

  2. Small Molecule Modulators of α-Synuclein Phase Separation

    Article • ACS Chemical Neuroscience, August 2025, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  3. Spatio-temporal regulation of ligand trafficking and TLR9 activation involves PIEZO1 mechanosensing in human plasmacytoid dendritic cells

    Article • August 2025, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  4. Investigating the Stability, Flexibility, and Phase Separation Properties of H46R and H80R Disease Mutants of SOD1: Insights into ALS Pathogenesis

    Article • Biochemistry, July 2025, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  5. Heterotypic Protein Interactions Modulate the Condensate Dynamics and Aggregation of α-Synuclein

    Article • July 2025, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  6. Multivalent interaction induces phase separation and formation of more toxic aggregates of α-syn in a yeast model of Parkinson’s disease

    Article • April 2025, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  7. Influence of Magnesium Ions and Crowding Agents on Structure and Stability of RNA Aptamers

    Article • Biochemistry, January 2025, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  8. Leishmania protein KMP-11 modulates cholesterol transport and membrane fluidity to facilitate host cell invasion

    Article • EMBO Reports, October 2024, Springer Science + Business Media

    Krishnananda Chattopadhyay

  9. Studies of Protein Phase Separation Using Leishmania Kinetoplastid Membrane Protein-11

    Article • The Journal of Physical Chemistry B, October 2024, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  10. Mapping DHPS Evolvability: Identification of Novel Evolutionarily Critical Sub-Structure through Evolutionary and Structural Analyses of DHPS

    Article • October 2024, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  11. Crowder induced conformational fluctuations modulate the phase separation of yeast SUP35 NM domain

    Article • August 2024, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  12. Mechanism of host cell invasion byLeishmaniathrough KMP-11 mediated cholesterol-transport and membrane phase transition

    Article • July 2024, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  13. Amyloid Beta Oligomers Accelerate ATP-Dependent Phase Separation of miRNA-Bound Ago2 to RNA Processing Bodiesin vitro

    Article • March 2024, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  14. Conformational switch of a peptide provides a novel strategy to design peptide loaded porous organic polymer for Pyroptosis pathway mediated cancer therapy

    Article • March 2024, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  15. Curcumin-based Nanoformulation for the Pyroptotic Death of MDA-MB-231 Cells

    Article • ACS Applied Nano Materials, February 2024, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  16. Quercetin@Gd3+ doped Prussian blue nanocubes induce the pyroptotic death of MDA-MB-231 cells: combinational targeted multimodal therapy, dual modal MRI, intuitive modelling of r1–r2 relaxivities

    Article • Journal of Materials Chemistry B, January 2023, Royal Society of Chemistry

    Krishnananda Chattopadhyay

  17. A Zn‐dependent structural transition of SOD1 modulates its ability to undergo phase separation

    Article • The EMBO Journal, November 2022, EMBO

    Bidisha Das, Krishnananda Chattopadhyay

  18. Zn-dependent structural transition of SOD1 modulates its ability to undergo liquid-liquid phase separation

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Bidisha Das, Krishnananda Chattopadhyay

  19. Cholesterol in Synaptic Vesicle Membranes Regulates the Vesicle-Binding, Function, and Aggregation of α-Synuclein

    Article • The Journal of Physical Chemistry B, September 2021, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  20. In vitro reconstitution demonstrates the amyloid-beta mediated myelin membrane deformation

    Article • August 2021, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  21. Role of Conformational Change and Glucose Binding Sites in the Enhanced Glucose Tolerance of Agrobacterium tumefaciens 5A GH1 β-Glucosidase Mutants

    Article • The Journal of Physical Chemistry B, August 2021, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  22. IMMUND: an Early Stage Diagnostic and Therapeutic Frame for Neurodegenerative Diseases and Multiple Sclerosis based on Immunological Markers

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  23. Conformational distortion in a fibril-forming oligomer arrests alpha-Synuclein fibrillation and minimizes its toxic effects

    Article • Communications Biology, May 2021, Springer Science + Business Media

    Krishnananda Chattopadhyay

  24. The metal cofactor zinc and interacting membranes modulate SOD1 conformation-aggregation landscape in an in vitro ALS model

    Article • eLife, April 2021, eLife

    Bidisha Das, Krishnananda Chattopadhyay

  25. Membrane composition and lipid to protein ratio modulate amyloid kinetics of yeast prion protein

    Article • RSC Chemical Biology, January 2021, Royal Society of Chemistry

    Krishnananda Chattopadhyay

  26. Modulation of α-Synuclein Fibrillation by Ultrasmall and Biocompatible Gold Nanoclusters

    Article • ACS Chemical Neuroscience, October 2020, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  27. Correlation between CNS Tuberculosis and the COVID-19 Pandemic: The Neurological and Therapeutic Insights

    Article • ACS Chemical Neuroscience, September 2020, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  28. Membrane composition and lipid to protein ratio modulate amyloid kinetics of yeast prion protein

    Article • August 2020, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  29. The metal cofactor zinc and interacting membranes modulate SOD1 conformation-aggregation landscape in anin vitroALS Model

    Article • July 2020, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  30. The bright and dark sides of protein conformational switches and the unifying forces of infections

    Article • Communications Biology, July 2020, Springer Science + Business Media

    Krishnananda Chattopadhyay

  31. A Novel Cyclic Mobile Transporter Can Induce Apoptosis by Facilitating Chloride Anion Transport into Cells

    Article • ACS Omega, July 2020, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  32. An exploration of the SARS-CoV-2 spike receptor binding domain (RBD) – a complex palette of evolutionary and structural features

    Article • June 2020, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  33. A Novel Tool to Investigate the Early and Late Stages of α-Synuclein Aggregation

    Article • ACS Chemical Neuroscience, April 2020, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  34. Kinetoplastid Membrane Protein-11 Induces Pores in Anionic Phospholipid Membranes: Effect of Cholesterol

    Article • Langmuir, March 2020, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  35. Protein induced membrane phase transition facilitates leishmania infection

    Article • March 2020, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  36. MicroRNA exporter HuR clears the internalized pathogens by promoting pro‐inflammatory response in infected macrophages

    Article • EMBO Molecular Medicine, February 2020, EMBO

    Krishnananda Chattopadhyay

  37. Evolutionary Analyses of Sequence and Structure Space Unravel the Structural Facets of SOD1

    Article • Biomolecules, December 2019, MDPI AG

    Krishnananda Chattopadhyay

  38. Osmolytes ameliorate the effects of stress in the absence of the heat shock protein Hsp104 in Saccharomyces cerevisiae

    Article • PLOS One, September 2019, PLOS

    Krishnananda Chattopadhyay

  39. Conformational Switch Driven Membrane Pore Formation by Mycobacterium Secretory Protein MPT63 Induces Macrophage Cell Death

    Article • ACS Chemical Biology, June 2019, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  40. Network mapping of the conformational heterogeneity of SOD1 by deploying statistical cluster analysis of FTIR spectra

    Article • Cellular and Molecular Life Sciences, April 2019, Springer Science + Business Media

    Krishnananda Chattopadhyay

  41. Effect of Ergosterol on the Binding of KMP-11 with Phospholipid Membranes: Implications in Leishmaniasis

    Article • ACS Omega, March 2019, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  42. Cryo-Electron Microscopy Uncovers Key Residues within the Core of Alpha-Synuclein Fibrils

    Article • ACS Chemical Neuroscience, February 2019, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  43. Efficient Detection of Early Events of α-Synuclein Aggregation Using a Cysteine Specific Hybrid Scaffold

    Article • Biochemistry, January 2019, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  44. Modulation of α-Synuclein Aggregation by Cytochrome c Binding and Hetero-dityrosine Adduct Formation

    Article • ACS Chemical Neuroscience, January 2019, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  45. An aminoglycoside antibiotic inhibits both lipid-induced and solution-phase fibrillation of α-synuclein in vitro

    Article • Chemical Communications, January 2019, Royal Society of Chemistry

    Krishnananda Chattopadhyay

  46. Development of a near infrared Au–Ag bimetallic nanocluster for ultrasensitive detection of toxic Pb2+ ions in vitro and inside cells

    Article • Nanoscale Advances, January 2019, Royal Society of Chemistry

    Krishnananda Chattopadhyay

  47. Conformational-Switch Based Strategy Triggered by [18] π Heteroannulenes toward Reduction of Alpha Synuclein Oligomer Toxicity

    Article • ACS Chemical Neuroscience, October 2018, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  48. Interaction of α-Synuclein with ATP Synthase: Switching Role from Physiological to Pathological

    Article • ACS Chemical Neuroscience, August 2018, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  49. Cysteine sensing application of fluorescent gold nanoclusters prepared from protein amyloid

    Article • ACS Omega, July 2018, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  50. Chameleon sequences, nanoparticle conjugation and immunogenicity of a protein

    Article • Langmuir, July 2018, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  51. Aggregation of Alpha Synuclein In Vitro and Inside Cells

    Article • Scientific Reports, April 2018, Springer Science + Business Media

    Krishnananda Chattopadhyay

  52. Comparative Study of Toluidine Blue O and Methylene Blue Binding to Lysozyme and Their Inhibitory Effects on Protein Aggregation

    Article • ACS Omega, March 2018, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  53. The Role of Intestinal Fatty Acid Binding Proteins in Protecting Cells from Fatty Acid Induced Impairment of Mitochondrial Dynamics and Apoptosis

    Article • Cellular Physiology and Biochemistry, January 2018, Karger Publishers

    Krishnananda Chattopadhyay

  54. Understanding the Effect of Single Cysteine Mutations on Gold Nanoclusters as Studied by Spectroscopy and Density Functional Theory Modeling

    Article • Langmuir, October 2017, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  55. Small Molecules Attenuate the Interplay between Conformational Fluctuations, Early Oligomerization and Amyloidosis of Alpha Synuclein

    Article • August 2017, Cold Spring Harbor Laboratory Press

    Krishnananda Chattopadhyay

  56. Interaction of KMP-11 with Phospholipid Membranes and Its Implications in Leishmaniasis: Effects of Single Tryptophan Mutations and Cholesterol

    Article • The Journal of Physical Chemistry B, February 2017, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  57. Early Sodium Dodecyl Sulfate Induced Collapse of α-Synuclein Correlates with Its Amyloid Formation

    Article • ACS Chemical Neuroscience, February 2015, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  58. Inhibiting the early events in Parkinson's disease

    Article • Langmuir, February 2015, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  59. pH-induced structural change of a multi-tryptophan protein MPT63 with immunoglobulin-like fold: identification of perturbed tryptophan residue/residues

    Article • Journal of Biomolecular Structure and Dynamics, January 2015, Taylor & Francis

    Krishnananda Chattopadhyay

  60. Enzymatic and Regulatory Attributes of Trehalose-6-Phosphate Phosphatase fromCandida utilisand its Role During Thermal Stress

    Article • Journal of Cellular Physiology, May 2014, Wiley

    Krishnananda Chattopadhyay

  61. Studies of Early Events of Folding of a Predominately β-Sheet Protein Using Fluorescence Correlation Spectroscopy and Other Biophysical Methods

    Article • Biochemistry, February 2014, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  62. Studies of protein folding and dynamics using single molecule fluorescence spectroscopy

    Article • Physical Chemistry Chemical Physics, January 2014, Royal Society of Chemistry

    Krishnananda Chattopadhyay

  63. Study of binding interactions between MPT63 protein and Au nanocluster

    Article • RSC Advances, January 2014, Royal Society of Chemistry

    Krishnananda Chattopadhyay

  64. A small molecule chemical chaperone optimizes its unfolded state contraction and denaturant like properties

    Article • Scientific Reports, December 2013, Springer Science + Business Media

    Krishnananda Chattopadhyay

  65. Fluorescence Correlation Spectroscopy Study on the Effects of the Shape and Size of a Protein on Its Diffusion Inside a Crowded Environment

    Article • Langmuir, November 2013, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  66. Surface Coating Rescues Proteins from Magnetite Nanoparticle Induced Damage

    Article • Particle & Particle Systems Characterization, March 2013, Wiley

    Krishnananda Chattopadhyay

  67. Unusual Optical Resolution of All Four Tryptophan Residues in MPT63 Protein by Phosphorescence Spectroscopy: Assignment and Significance

    Article • The Journal of Physical Chemistry B, October 2012, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  68. Purification and characterization of a trehalase–invertase enzyme with dual activity from Candida utilis

    Article • Archives of Biochemistry and Biophysics, June 2012, Elsevier

    Krishnananda Chattopadhyay

  69. The Presence of the Iron-Sulfur Motif Is Important for the Conformational Stability of the Antiviral Protein, Viperin

    Article • PLOS One, February 2012, PLOS

    Krishnananda Chattopadhyay

  70. Interconnection of Salt-induced Hydrophobic Compaction and Secondary Structure Formation Depends on Solution Conditions

    Article • Journal of Biological Chemistry, February 2012, American Society for Biochemistry & Molecular Biology (ASBMB)

    Krishnananda Chattopadhyay

  71. A Facile Synthesis of PEG-Coated Magnetite (Fe 3 O 4 ) Nanoparticles and Their Prevention of the Reduction of Cytochrome C

    Article • ACS Applied Materials & Interfaces, January 2012, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  72. Interaction of Gold Nanoparticle with Human Serum Albumin (HSA) Protein Using Surface Energy Transfer

    Article • The Journal of Physical Chemistry C, December 2011, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  73. Effects of Arginine and Other Solution Additives on the Self-Association of Different Surfactants: An Investigation at Single-Molecule Resolution

    Article • Langmuir, May 2011, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  74. Ag−TiO2 Nanoparticle Codoped SiO2 Films on ZrO2 Barrier-Coated Glass Substrates with Antibacterial Activity in Ambient Condition

    Article • ACS Applied Materials & Interfaces, August 2010, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  75. Role of Protein Stabilizers on the Conformation of the Unfolded State of Cytochromecand Its Early Folding Kinetics

    Article • Journal of Biological Chemistry, June 2010, American Society for Biochemistry & Molecular Biology (ASBMB)

    Krishnananda Chattopadhyay

  76. Magnetic susceptibilities, crystal field Stark energies, and hyperfine behavior of Sm3+ in hexagonal single crystals of Sm(CF3SO3)3⋅9H2O

    Article • Journal of Applied Physics, March 2009, American Institute of Physics

    Krishnananda Chattopadhyay

  77. Effect of Arginine on Protein Aggregation Studied by Fluorescence Correlation Spectroscopy and Other Biophysical Methods†

    Article • Biochemistry, February 2009, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  78. Steady-state and time-resolved fluorescence studies of the intestinal fatty acid binding protein

    Article • Proteins Structure Function and Bioinformatics, January 2006, Wiley

    Krishnananda Chattopadhyay

  79. The kinetics of conformational fluctuations in an unfolded protein measured by fluorescence methods

    Article • Proceedings of the National Academy of Sciences, February 2005, Proceedings of the National Academy of Sciences

    Krishnananda Chattopadhyay

  80. Measuring Unfolding of Proteins in the Presence of Denaturant Using Fluorescence Correlation Spectroscopy

    Article • Biophysical Journal, February 2005, Elsevier

    Krishnananda Chattopadhyay

  81. Stabilization of Partially Folded States of Cytochrome C in Aqueous Surfactant:  Effects of Ionic and Hydrophobic Interactions†

    Article • Biochemistry, December 2003, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  82. Measurement of microsecond dynamic motion in the intestinal fatty acid binding protein by using fluorescence correlation spectroscopy

    Article • Proceedings of the National Academy of Sciences, October 2002, Proceedings of the National Academy of Sciences

    Krishnananda Chattopadhyay

  83. NMR studies on interaction of lauryl maltoside with cytochrome c oxidase: a model for surfactant interaction with the membrane protein

    Article • Journal of Inorganic Biochemistry, July 2002, Elsevier

    Krishnananda Chattopadhyay

  84. The Intestinal Fatty Acid Binding Protein:  The Role of Turns in Fast and Slow Folding Processes†

    Article • Biochemistry, March 2002, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  85. What fluorescence correlation spectroscopy can tell us about unfolded proteins

    Article • January 2002, Elsevier

    Krishnananda Chattopadhyay

  86. Direct electrochemistry of heme proteins: effect of electrode surface modification by neutral surfactants

    Article • Bioelectrochemistry, January 2001, Elsevier

    Krishnananda Chattopadhyay

  87. Structural and Conformational Stability of Horseradish Peroxidase:  Effect of Temperature and pH

    Article • Biochemistry, January 2000, American Chemical Society (ACS)

    Krishnananda Chattopadhyay

  88. Direct electrochemical oxidation of horseradish peroxidase: cyclic voltammetric and spectroelectrochemical studies

    Article • New Journal of Chemistry, January 1999, Royal Society of Chemistry

    Krishnananda Chattopadhyay