All Stories

  1. Back to the Future: Repurposing Metformin, a Metabolically Active Drug, to Treat Mild-to-Moderate Ulcerative Colitis

    Article • Metabolites, March 2026, MDPI AG

    Professor Gabrio Bassotti

  2. Diagnostic–Therapeutic Care Pathway in Chronic Constipation: AIGO (Italian Association of Gastroenterologists and Gastrointestinal Endoscopists) Position Paper

    Article • Journal of Clinical Medicine, March 2026, MDPI AG

    Professor Gabrio Bassotti

  3. Persistent Abdominal Pain in Patients with Inactive Inflammatory Bowel Disease: A Clinical Conundrum

    Article • Inflammatory Bowel Diseases, February 2026, Oxford University Press (OUP)

    Professor Gabrio Bassotti

  4. Repurposing metformin: another possible bullet to target cheaply ulcerative colitis

    Article • Internal and Emergency Medicine, February 2026, Springer Science + Business Media

    Professor Gabrio Bassotti

  5. Gut–Liver Axis, Microbiota, Bile Acids, and Immune Response in Pathogenesis of Primary Sclerosing Cholangitis: An Overview

    Article • Journal of Clinical Medicine, November 2025, MDPI AG

    Professor Gabrio Bassotti

  6. 24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O’Beirne) activity in severely constipated patients

    Article • Digestive and Liver Disease, November 2025, Elsevier

    Professor Gabrio Bassotti

  7. Ultrasound assessment of constipation: do not put the cart before the horse

    Article • Internal and Emergency Medicine, September 2025, Springer Science + Business Media

    Professor Gabrio Bassotti

  8. The Sweet Side of Constipation: Colonic Motor Dysfunction in Diabetes Mellitus

    Article • Nutrients, September 2025, MDPI AG

    Professor Gabrio Bassotti

  9. Most prominent challenges in translational neuroscience and strategic solutions to bridge the gaps: Perspectives from an editorial board interrogation

    Article • Exploration of Neuroscience, August 2025, Open Exploration Publishing

    Professor Gabrio Bassotti

  10. Constipation in Ulcerative Colitis: An Underestimated Problem

    Article • Journal of Clinical Medicine, August 2025, MDPI AG

    Professor Gabrio Bassotti

  11. Histological differentiation of inflammatory bowel disease from “diverticular colitis”: an actual possibility or the fog is still thick?

    Article • Virchows Archiv, July 2025, Springer Science + Business Media

    Professor Gabrio Bassotti

  12. Neurogastroenterology: The Cinderella among the ecological niches of gastroenterology?

    Article • Digestive and Liver Disease, July 2025, Elsevier

    Professor Gabrio Bassotti

  13. Transcutaneous Auricular Vagal Nerve Stimulation to Treat Chronic Constipation: Another Therapeutic Failure?

    Article • United European Gastroenterology Journal, June 2025, Wiley

    Professor Gabrio Bassotti

  14. Author's reply: Claudin-2 immunochemistry in IBD

    Article • Digestive and Liver Disease, June 2025, Elsevier

    Professor Gabrio Bassotti

  15. Diagnosing Ulcerative Colitis: Should We Go Beyond the Surface?

    Article • Journal of Clinical Medicine, May 2025, MDPI AG

    Professor Gabrio Bassotti

  16. Histological healing in IBD: Ready for prime time?

    Article • Digestive and Liver Disease, May 2025, Elsevier

    Professor Gabrio Bassotti

  17. Moving forward: may some of “functional” gut disorders be reclassified as enteric neuro-gliopathies?

    Article • April 2025, Open Exploration Publishing

    Professor Gabrio Bassotti

  18. Claudin-2: A marker for a better evaluation of histological mucosal healing in inflammatory bowel diseases

    Article • Digestive and Liver Disease, April 2025, Elsevier

    Professor Gabrio Bassotti

  19. Colonic motility investigation by modern techniques: time to ‘reclaim’ the value of physiology?

    Article • Gut, December 2024, BMJ

    Professor Gabrio Bassotti

  20. Mucosal Healing in Inflammatory Bowel Diseases: Still too Many Irons on the Fire

    Article • United European Gastroenterology Journal, November 2024, Wiley

    Professor Gabrio Bassotti

  21. The Diagnosis and Management of Chronic Constipation in Italy: Results from a Survey Conducted among Italian Gastroenterologists

    Article • Journal of Clinical Medicine, October 2024, MDPI AG

    Bruno Annibale, Professor Gabrio Bassotti

  22. Bowel movement alterations predict the severity of diverticular disease and the risk of acute diverticulitis: a prospective, international st

    Article • Intestinal Research, August 2024, Korean Association for the Study of Intestinal Diseases (KAMJE)

    Prof. Antonio Tursi, Professor Gabrio Bassotti

  23. Defining Occasional Constipation: A Straitjacket?

    Article • Clinical Gastroenterology and Hepatology, July 2024, Elsevier

    Professor Gabrio Bassotti

  24. PhosphoLipidome Alteration Induced by Clostridioides difficile Toxin B in Enteric Glial Cells

    Article • Cells, June 2024, MDPI AG

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  25. Editorial: Sonographic assessment of colonic content—A new tool for constipation?

    Article • Alimentary Pharmacology & Therapeutics, June 2024, Wiley

    Professor Gabrio Bassotti

  26. Targeting diarrhea-predominant irritable bowel syndrome: hopes or hypes?

    Article • Expert Opinion on Investigational Drugs, April 2024, Taylor & Francis

    Professor Gabrio Bassotti

  27. Treating colonic diverticula with rifaximin: a call to action

    Article • Internal and Emergency Medicine, April 2024, Springer Science + Business Media

    Professor Gabrio Bassotti

  28. An Unusually Rapid-Onset Portal Hypertension

    Article • The American Journal of Medicine, April 2024, Elsevier

    Professor Gabrio Bassotti

  29. Pro-Inflammatory Cytokines Enhanced In Vitro Cytotoxic Activity of Clostridioides difficile Toxin B in Enteric Glial Cells: The Achilles Heel of Clostridioides difficile Infection?

    Article • International Journal of Molecular Sciences, January 2024, MDPI AG

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  30. Intestinal ultrasound, an underutilized tool for assessing colonic motility

    Article • AJP Gastrointestinal and Liver Physiology, January 2024, American Physiological Society

    Professor Gabrio Bassotti

  31. Ten years of successful linaclotide treatment in a patient with intestinal pseudo-obstruction due to Ehlers-Danlos syndrome

    Article • Internal and Emergency Medicine, December 2023, Springer Science + Business Media

    Professor Gabrio Bassotti

  32. Letter: Abdominal pain in inflammatory bowel disease patients in remission—A look beyond psychosocial factors

    Article • Alimentary Pharmacology & Therapeutics, November 2023, Wiley

    Professor Gabrio Bassotti

  33. Letter: The importance of histological assessment—a further stride in STRIDE

    Article • Alimentary Pharmacology & Therapeutics, November 2023, Wiley

    Professor Gabrio Bassotti

  34. Relief from behind: enemas, the back door enforcement to help treating chronic constipation in adults

    Article • Expert Review of Gastroenterology & Hepatology, October 2023, Taylor & Francis

    Professor Gabrio Bassotti

  35. Misinterpreting Diarrhea-Predominant Irritable Bowel Syndrome and Functional Diarrhea: Pathophysiological Highlights

    Article • Journal of Clinical Medicine, September 2023, MDPI AG

    Professor Gabrio Bassotti

  36. Role of the Alteration in Calcium Homeostasis in Cell Death Induced by Clostridioides difficile Toxin A and Toxin B

    Article • Biology, August 2023, MDPI AG

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  37. Diverticular Inflammation and Complication Assessment classification, CODA score and fecal calprotectin in clinical assessment of patients with diverticular disease: A decision curve analysis

    Article • United European Gastroenterology Journal, August 2023, Wiley

    Prof. Antonio Tursi, Professor Gabrio Bassotti

  38. Inflammatory Bowel Diseases: Does One Histological Score Fit All?

    Article • Diagnostics, June 2023, MDPI AG

    Professor Gabrio Bassotti

  39. Pathology: One Score Fits All?

    Article • May 2023, MDPI AG

    Professor Gabrio Bassotti

  40. Clostridioides difficile Toxin B Induced Senescence: A New Pathologic Player for Colorectal Cancer?

    Article • International Journal of Molecular Sciences, May 2023, MDPI AG

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  41. Possible Role of Carbocysteine Syrup in the Deflation of Percutaneous Endoscopic Gastrostomy Balloons

    Article • Clinics and Practice, March 2023, MDPI AG

    Professor Gabrio Bassotti

  42. Considerations for laxatives in terms of their interactions with other drugs

    Article • Expert Opinion on Drug Metabolism & Toxicology, March 2023, Taylor & Francis

    Professor Gabrio Bassotti

  43. Exploring Pharmacological Treatments for Chronic Idiopathic Constipation in Adults: A Look Back to the Future

    Article • Journal of Clinical Medicine, February 2023, MDPI AG

    Professor Gabrio Bassotti

  44. Pharmacotherapeutic advances for chronic idiopathic constipation in adults

    Article • Expert Opinion on Pharmacotherapy, November 2022, Taylor & Francis

    Professor Gabrio Bassotti

  45. Unexpected findings in a bright liver

    Article • Journal of Internal Medicine, October 2022, Wiley

    Paolo Maria Brunori, Professor Gabrio Bassotti

  46. More than twenty years of medical treatment in a patient with esophageal achalasia

    Article • Digestive and Liver Disease, October 2022, Elsevier

    Professor Gabrio Bassotti

  47. Clostridioides difficile toxin B alone and with pro-inflammatory cytokines induces apoptosis in enteric glial cells by activating three different signalling pathways mediated by caspases, calpains and cathepsin B

    Article • Cellular and Molecular Life Sciences, July 2022, Springer Science + Business Media

    Dr Katia Fettucciari, Professor Gabrio Bassotti

  48. Irritable Bowel Syndrome: A Multifaceted World Still to Discover

    Article • Journal of Clinical Medicine, July 2022, MDPI AG

    Professor Gabrio Bassotti

  49. Translational Gap between Guidelines and Clinical Medicine: The Viewpoint of Italian General Practitioners in the Management of IBS

    Article • Journal of Clinical Medicine, July 2022, MDPI AG

    Professor Gabrio Bassotti

  50. Gluten Induces Subtle Histological Changes in Duodenal Mucosa of Patients with Non-Coeliac Gluten Sensitivity: A Multicentre Study

    Article • Nutrients, June 2022, MDPI AG

    Professor Gabrio Bassotti

  51. Histological Features of Celiac-Disease-like Conditions Related to Immune Checkpoint Inhibitors Therapy: A Signal to Keep in Mind for Pathologists

    Article • Diagnostics, February 2022, MDPI AG

    Professor Gabrio Bassotti

  52. Neuromuscular Function Abnormalities

    Article • January 2022, Springer Science + Business Media

    Professor Gabrio Bassotti

  53. Clostridioides difficile Infection in Patients with Inflammatory Bowel Disease May be Favoured by the Effects of Proinflammatory Cytokines on the Enteroglial Network

    Article • Journal of Inflammation Research, December 2021, Taylor & Francis

    Professor Gabrio Bassotti, Dr Katia Fettucciari

  54. The Management of Acute Colonic Diverticulitis in the COVID-19 Era: A Scoping Review

    Article • Medicina, October 2021, MDPI AG

    Professor Gabrio Bassotti

  55. Chronic Idiopathic Constipation in Adults: A Review on Current Guidelines and Emerging Treatment Options

    Article • Clinical and Experimental Gastroenterology, October 2021, Taylor & Francis

    Professor Gabrio Bassotti

  56. New pharmacologic treatments for idiopathic chronic constipation: a financial strain for strainers

    Article • Expert Review of Gastroenterology & Hepatology, April 2021, Taylor & Francis

    Professor Gabrio Bassotti

  57. Dermatological Manifestations in Inflammatory Bowel Diseases

    Article • Journal of Clinical Medicine, January 2021, MDPI AG

    Professor Gabrio Bassotti

  58. 1907–2020: more than one century of colonic mass movements in humans

    Article • AJP Gastrointestinal and Liver Physiology, January 2021, American Physiological Society

    Professor Gabrio Bassotti

  59. Proinflammatory Cytokines: Possible Accomplices for the Systemic Effects of Clostridioides difficile Toxin B

    Article • Journal of Inflammation Research, January 2021, Taylor & Francis

    Professor Gabrio Bassotti, Dr Katia Fettucciari

  60. Abdominal Symptoms and Colonic Diverticula in Marfan’s Syndrome: A Clinical and Ultrasonographic Case Control Study

    Article • Journal of Clinical Medicine, September 2020, MDPI AG

    Professor Gabrio Bassotti

  61. The cytotoxic synergy betweenClostridioides difficiletoxin B and proinflammatory cytokines: an unholy alliance favoring the onset ofClostridioides difficileinfection and relapses

    Article • MicrobiologyOpen, July 2020, Wiley

    Professor Gabrio Bassotti, Dr Katia Fettucciari

  62. Irritable Bowel Syndrome and Gluten-Related Disorders

    Article • Nutrients, April 2020, MDPI AG

    Professor Gabrio Bassotti

  63. When physiology meets technology: redefining colonic mass movements

    Article • AJP Gastrointestinal and Liver Physiology, April 2020, American Physiological Society

    Professor Gabrio Bassotti

  64. Side Effects Associated with Probiotic Use in Adult Patients with Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

    Article • Nutrients, December 2019, MDPI AG

    Professor Gabrio Bassotti

  65. microRNA‐mRNA network model in patients with achalasia

    Article • Neurogastroenterology & Motility, November 2019, Wiley

    Professor Gabrio Bassotti

  66. Plecanatide for the treatment of chronic idiopathic constipation in adult patients

    Article • Expert Review of Clinical Pharmacology, October 2019, Taylor & Francis

    Professor Gabrio Bassotti, Massimo Bellini

  67. First translational consensus on terminology and definitions of colonic motility in animals and humans studied by manometric and other techniques

    Article • Nature Reviews Gastroenterology & Hepatology, July 2019, Springer Science + Business Media

    Professor Gabrio Bassotti

  68. Pneumococcal vaccination in celiac disease

    Article • Expert Review of Gastroenterology & Hepatology, April 2019, Taylor & Francis

    Professor Gabrio Bassotti

  69. Prucalopride for the treatment of constipation: a view from 2015 and beyond

    Article • Expert Review of Gastroenterology & Hepatology, January 2019, Taylor & Francis

    Professor Gabrio Bassotti, Massimo Bellini

  70. Long-term treatment with linaclotide of intestinal pseudo-obstruction secondary to Ehlers-Danlos syndrome

    Article • Digestive and Liver Disease, January 2019, Elsevier

    Professor Gabrio Bassotti

  71. Different perception of chronic constipation between patients and gastroenterologists

    Article • Neurogastroenterology & Motility, March 2018, Wiley

    Professor Gabrio Bassotti

  72. Effects of probiotic bacteria on mucosal polyamines levels in dogs with IBD and colonic polyps: a preliminary study

    Article • Beneficial Microbes, February 2018, Wageningen Academic Publishers

    Dr Katia Fettucciari, Professor Gabrio Bassotti, Giacomo Rossi

  73. Usefulness of Bisacodyl Testing on Therapeutic Outcomes in Refractory Constipation

    Article • Digestive Diseases and Sciences, February 2018, Springer Science + Business Media

    Professor Gabrio Bassotti

  74. Effects of a probiotic (SLAB51™) on clinical and histologic variables and microbiota of cats with chronic constipation/megacolon: a pilot study

    Article • Beneficial Microbes, January 2018, Wageningen Academic Publishers

    Professor Gabrio Bassotti, Giacomo Rossi

  75. Helicobacter pylori infection and occurrence of celiac disease in subjects HLA-DQ2/DQ8 positive: A prospective study

    Article • Helicobacter, January 2018, Wiley

    Professor Gabrio Bassotti

  76. Clostridium difficile-related postinfectious IBS: a case of enteroglial microbiological stalking and/or the solution of a conundrum?

    Article • Cellular and Molecular Life Sciences, December 2017, Springer Science + Business Media

    Professor Gabrio Bassotti, Dr Katia Fettucciari

  77. Usefulness of Different Pathological Scores to Assess Healing of the Mucosa in Inflammatory Bowel Diseases: A Real Life Study

    Article • Scientific Reports, July 2017, Springer Science + Business Media

    Professor Gabrio Bassotti

  78. Toward optimal processing of endoscopic submucosal dissection specimens

    Article • Virchows Archiv, February 2017, Springer Science + Business Media

    Professor Gabrio Bassotti

  79. Eosinophilia - associated basal plasmacytosis: an early and sensitive histologic feature of inflammatory bowel disease

    Article • Apmis, January 2017, Wiley

    Professor Gabrio Bassotti

  80. Histopathological findings of extra-ileal manifestations at initial diagnosis of Crohn’s disease-related ileitis

    Article • Virchows Archiv, January 2017, Springer Science + Business Media

    Professor Gabrio Bassotti

  81. The enteric nervous system in patients with calculous and acalculous gallbladder

    Article • Digestive and Liver Disease, July 2016, Elsevier

    Professor Gabrio Bassotti

  82. Intestinal metaplasia in Barrett's oesophagus: An essential factor to predict the risk of dysplasia and cancer development

    Article • Digestive and Liver Disease, February 2016, Elsevier

    Professor Gabrio Bassotti

  83. Letter: histological assessment of disease activity in ulcerative colitis - the problem of score evaluation and validation

    Article • Alimentary Pharmacology & Therapeutics, January 2016, Wiley

    Professor Gabrio Bassotti

  84. Assessing mucosal healing in ulcerative colitis: the simpler, the better…

    Article • Endoscopy, July 2015, Thieme Publishing Group

    Professor Gabrio Bassotti

  85. Editorial: enhancing gluten digestion in the stomach - a further help to minimise unintentional ingestion?

    Article • Alimentary Pharmacology & Therapeutics, July 2015, Wiley

    Professor Gabrio Bassotti

  86. Controlling defecation: to be (predator) or not to be (prey), that is the question…

    Article • Seminars in Musculoskeletal Radiology, May 2015, Thieme Publishing Group

    Professor Gabrio Bassotti

  87. Severe Gastritis with DoubleHelicobacterspp. Infection Associated with Barrett's Esophagus in a Cheetah

    Article • Helicobacter, November 2014, Wiley

    Professor Gabrio Bassotti