All Stories

  1. Selenium Entities: Promising Scaffolds for the Treatment of Cancer and Leishmania

    Article • Current Organic Synthesis, February 2018, Bentham Science Publishers

    Daniel Plano, Professor Daniel Plano Amatriain

  2. Methylselenol release as a cytotoxic tool: a study of the mechanism of the activity achieved by two series of methylselenocarbamate derivatives

    Article • Metallomics, January 2018, Oxford University Press (OUP)

    Professor Daniel Plano Amatriain

  3. A diphenyldiselenide derivative induces autophagy via JNK in HTB-54 lung cancer cells

    Article • Journal of Cellular and Molecular Medicine, September 2017, Wiley

    Daniel Plano, Professor Daniel Plano Amatriain

  4. Novel Methylselenoesters as Antiproliferative Agents

    Article • Molecules, August 2017, MDPI AG

    Professor Daniel Plano Amatriain

  5. Topological and quantum molecular descriptors as effective tools for analyzing cytotoxic activity achieved by a series of (diselanediyldibenzene-4,1-diylnide)biscarbamate derivatives

    Article • Journal of Molecular Graphics and Modelling, May 2017, Elsevier

    Professor Daniel Plano Amatriain

  6. Methods of selecting combination therapy for colorectal cancer patients: a patent evaluation of US20160025730A1

    Article • Expert Opinion on Therapeutic Patents, April 2017, Taylor & Francis

    Daniel Plano, Professor Daniel Plano Amatriain

  7. Library of Seleno-Compounds as Novel Agents against Leishmania Species

    Article • Antimicrobial Agents and Chemotherapy, March 2017, ASM Journals

    Professor Daniel Plano Amatriain, Professor Silvia Pérez-Silanes

  8. Chalcogen containing heterocyclic scaffolds: New hybrids with antitumoral activity

    Article • European Journal of Medicinal Chemistry, November 2016, Elsevier

    Professor Daniel Plano Amatriain

  9. Abstract 3061: AS-10: a new small molecule with promising activity against pancreatic cancer

    Article • Cancer Research, July 2016, American Association for Cancer Research (AACR)

    Professor Daniel Plano Amatriain

  10. Novel seleno- and thio-urea derivatives with potent in vitro activities against several cancer cell lines

    Article • European Journal of Medicinal Chemistry, May 2016, Elsevier

    Professor Daniel Plano Amatriain

  11. Novel Heteroaryl Selenocyanates and Diselenides as Potent Antileishmanial Agents

    Article • Antimicrobial Agents and Chemotherapy, April 2016, ASM Journals

    Professor Daniel Plano Amatriain

  12. Design, Synthesis, and Biological Evaluation of Novel Selenium (Se-NSAID) Molecules as Anticancer Agents

    Article • Journal of Medicinal Chemistry, January 2016, American Chemical Society (ACS)

    Professor Daniel Plano Amatriain

  13. Leishmanicidal Activities of Novel Methylseleno-Imidocarbamates

    Article • Antimicrobial Agents and Chemotherapy, July 2015, ASM Journals

    Professor Daniel Plano Amatriain

  14. Molecular descriptors calculation as a tool in the analysis of the antileishmanial activity achieved by two series of diselenide derivatives. An insight into its potential action mechanism

    Article • Journal of Molecular Graphics and Modelling, July 2015, Elsevier

    Professor Daniel Plano Amatriain

  15. In vitro radical scavenging and cytotoxic activities of novel hybrid selenocarbamates

    Article • Bioorganic & Medicinal Chemistry, April 2015, Elsevier

    Professor Daniel Plano Amatriain

  16. Strong induction of iodothyronine deiodinases by chemotherapeutic selenocompounds

    Article • Metallomics, January 2015, Oxford University Press (OUP)

    Professor Lutz Schomburg, Professor Daniel Plano Amatriain

  17. A dihydroselenoquinazoline inhibits S6 ribosomal protein signalling, induces apoptosis and inhibits autophagy in MCF-7 cells

    Article • European Journal of Pharmaceutical Sciences, October 2014, Elsevier

    Professor Daniel Plano Amatriain

  18. Abstract 814: Novel aspirin based selenium compounds as therapy against pancreatic cancer

    Article • Cancer Research, September 2014, American Association for Cancer Research (AACR)

    Professor Daniel Plano Amatriain

  19. Abstract 2139: Pre-clinical chemopreventive efficacy of a novel hybridp-XSC-aspirin compound in a NNK-induced A/J mouse lung cancer model

    Article • Cancer Research, September 2014, American Association for Cancer Research (AACR)

    Professor Daniel Plano Amatriain

  20. Importance of Sphingosine Kinase (SphK) as a Target in Developing Cancer Therapeutics and Recent Developments in the Synthesis of Novel SphK Inhibitors

    Article • Journal of Medicinal Chemistry, February 2014, American Chemical Society (ACS)

    Professor Daniel Plano Amatriain

  21. Synthesis and antiproliferative activity of novel selenoester derivatives

    Article • European Journal of Medicinal Chemistry, February 2014, Elsevier

    Professor Daniel Plano Amatriain

  22. Cytotoxic Effects of Seleno-Trastuzumab on Transtuzumab Resistant JIMT-1 Breast Cancer Cell Line

    Article • Free Radical Biology and Medicine, November 2013, Elsevier

    Professor Daniel Plano Amatriain

  23. Novel quinazoline and pyrido[2,3-d]pyrimidine derivatives and their hydroselenite salts as antitumoral agents

    Article • ARKIVOC, August 2013, ARKAT USA, Inc.

    Professor Daniel Plano Amatriain

  24. Structural variations on antitumour agents derived from bisacylimidoselenocarbamate. A proposal for structure–activity relationships based on the analysis of conformational behaviour

    Article • European Journal of Medicinal Chemistry, August 2013, Elsevier

    Professor Daniel Plano Amatriain

  25. Bisacylimidoselenocarbamates Cause G2/M Arrest Associated with the Modulation of CDK1 and Chk2 in Human Breast Cancer MCF-7 Cells

    Article • Current Medicinal Chemistry, March 2013, Bentham Science Publishers

    Professor Daniel Plano Amatriain

  26. Cytotoxic and Proapototic Activities of Imidoselenocarbamate Derivatives Are Dependent on the Release of Methylselenol

    Article • Chemical Research in Toxicology, November 2012, American Chemical Society (ACS)

    Professor Daniel Plano Amatriain

  27. Innovative Lead Compounds and Formulation Strategies As Newer Kinetoplastid Therapies

    Article • Current Medicinal Chemistry, September 2012, Bentham Science Publishers

    Professor Juan M. Irache, Professor Daniel Plano Amatriain

  28. Novel structural insights for imidoselenocarbamates with antitumoral activity related to their ability to generate methylselenol

    Article • Bioorganic & Medicinal Chemistry, September 2012, Elsevier

    Professor Daniel Plano Amatriain

  29. Selenium Compounds, Apoptosis and Other Types of Cell Death: An Overview for Cancer Therapy

    Article • International Journal of Molecular Sciences, August 2012, MDPI AG

    Professor Daniel Plano Amatriain

  30. Thermal stability of selenium, sulfur and nitrogen analogous phthalazine derivatives

    Article • Journal of Thermal Analysis and Calorimetry, February 2012, Springer Science + Business Media

    Professor Daniel Plano Amatriain

  31. Structure- and cell-specific effects of imidoselenocarbamates on selenoprotein expression and activity in liver cells in culture

    Article • Metallomics, January 2012, Oxford University Press (OUP)

    Professor Daniel Plano Amatriain, Professor Lutz Schomburg

  32. Sulfur and selenium derivatives of quinazoline and pyrido[2,3-d]pyrimidine: Synthesis and study of their potential cytotoxic activity in vitro

    Article • European Journal of Medicinal Chemistry, January 2012, Elsevier

    Professor Daniel Plano Amatriain

  33. Selenocyanates and diselenides: A new class of potent antileishmanial agents

    Article • European Journal of Medicinal Chemistry, August 2011, Elsevier

    Professor Daniel Plano Amatriain

  34. Novel Library of Selenocompounds as Kinase Modulators

    Article • Molecules, July 2011, MDPI AG

    Professor Daniel Plano Amatriain

  35. Synthesis, characterization, crystal structure and cytotoxicity of 2,4-bis(selenomethyl)quinazoline

    Article • Structural Chemistry, June 2011, Springer Science + Business Media

    Professor Daniel Plano Amatriain

  36. Kinase Regulation by Sulfur and Selenium Containing Compounds

    Article • Current Cancer Drug Targets, May 2011, Bentham Science Publishers

    Professor Daniel Plano Amatriain

  37. Synthesis and antiproliferative activity of novel symmetrical alkylthio- and alkylseleno-imidocarbamates

    Article • European Journal of Medicinal Chemistry, January 2011, Elsevier

    Professor Daniel Plano Amatriain

  38. Synthesis and in vitro Anticancer Activities of some Selenadiazole Derivatives

    Article • Archiv der Pharmazie, November 2010, Wiley

    Professor Daniel Plano Amatriain

  39. Antioxidant-Prooxidant Properties of a New Organoselenium Compound Library

    Article • Molecules, October 2010, MDPI AG

    Professor Daniel Plano Amatriain

  40. Antileishmanial activity of imidothiocarbamates and imidoselenocarbamates

    Article • Zeitschrift für Parasitenkunde Parasitology Research, October 2010, Springer Science + Business Media

    Professor Daniel Plano Amatriain

  41. Study of polymorphism of organosulfur and organoselenium compounds

    Article • Journal of Thermal Analysis and Calorimetry, August 2010, Springer Science + Business Media

    Professor Daniel Plano Amatriain

  42. Synthesis and Pharmacological Screening of Several Aroyl and Heteroaroyl Selenylacetic Acid Derivatives as Cytotoxic and Antiproliferative Agents

    Article • Molecules, September 2009, MDPI AG

    Professor Daniel Plano Amatriain

  43. Thermal stability and decomposition of sulphur and selenium compounds

    Article • Journal of Thermal Analysis and Calorimetry, August 2009, Springer Science + Business Media

    Professor Daniel Plano Amatriain

  44. Selenium Compounds and Apoptotic Modulation: A New Perspective in Cancer Therapy

    Article • Mini-Reviews in Medicinal Chemistry, September 2008, Bentham Science Publishers

    Professor Daniel Plano Amatriain

  45. Novel potent organoselenium compounds as cytotoxic agents in prostate cancer cells

    Article • Bioorganic & Medicinal Chemistry Letters, December 2007, Elsevier

    Professor Daniel Plano Amatriain