All Stories

  1. Immune Cell Populations in Idiopathic Recurrent Pregnancy Loss and Unexplained Infertility in Venezuelan Admixed Women
  2. Assessment of Kir Genes in the Venezuelan Ad-Mixed Population with Either Idiopathic Recurrent Pregnancy Loss or Unexplained Infertility
  3. A perfect storm: the deadly intersection of sickle cell disease and COVID-19
  4. New Derivatives of Caracasine Acid with Anti-Leukemic Activity and Limited Effectiveness in Spheroid Cultures
  5. Food-Specific IgG Antibodies: Decoding Their Dual Role in Immune Tolerance and Food Intolerance
  6. The response of the Venezuelan population to the sinopharm vaccine
  7. Endometriosis: An Immunologist’s Perspective
  8. Specialized Pro-Resolving Lipid Mediators in Pulmonary Diseases: Molecular and Therapeutic Implications
  9. Identification of a novel Azaspirooxindolinone-based PROTAC for selective BTK degradation and enhanced anticancer activity
  10. Diethyldithiocarbamate-copper complex ignites the tumor microenvironment through NKG2D-NKG2DL axis
  11. Colchicine for the primary prevention of cardiovascular events
  12. Exploring the Immunological Aspects and Treatments of Recurrent Pregnancy Loss and Recurrent Implantation Failure
  13. Exploring How Adipose Tissue, Obesity, and Gender Influence the Immune Response to Vaccines: A Comprehensive Narrative Review
  14. Correction: De Sanctis et al. Lck Function and Modulation: Immune Cytotoxic Response and Tumor Treatment More Than a Simple Event. Cancers 2024, 16, 2630
  15. Polymer nanotherapeutics with the controlled release of acetylsalicylic acid and its derivatives inhibiting cyclooxygenase isoforms and reducing the production of pro-inflammatory mediators
  16. Exploring the Contrasts and Similarities of Dengue and SARS-CoV-2 Infections During the COVID-19 Era
  17. IgG Antibody Titers Against Ascaris lumbricoides, Strongyloides stercolaris, and Toxocara canis in Venezuelan Patients with Asthma or COPD
  18. PERFIL INMUNOLÓGICO EN INDIVIDUOS ADULTOS VENEZOLANOS CON INFECCIÓN AGUDA POR SARS–CoV-2
  19. Unlocking the Puzzle: Investigating the Role of Interleukin 17 Genetic Polymorphisms, Circulating Lymphocytes, and Serum Levels in Venezuelan Women with Recurrent Pregnancy Loss
  20. Interleukin-receptor antagonist and tumour necrosis factor inhibitors for the primary and secondary prevention of atherosclerotic cardiovascular diseases
  21. Microbiota and Recurrent Pregnancy Loss (RPL); More than a Simple Connection
  22. Role of Micronutrients in the Response to SARS-CoV-2 Infection in Pediatric Patients
  23. Lck Function and Modulation: Immune Cytotoxic Response and Tumor Treatment More Than a Simple Event
  24. ESTUDIO PILOTO DEL EFECTO DEL TIPO Y CONSERVACION DE LA MUESTRA Y MÉTODO, EN LA MEDICION DE LA CONCENTRACION DE LAS FRACCIONES C3 Y C4 DEL COMPLEMENTO.
  25. Inflammation, Autoimmunity and Neurodegenerative Diseases, Therapeutics and Beyond
  26. Genetic polymorphism in primary, recurrent pregnancy loss
  27. Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies
  28. Isoform-Directed Control of c-Myc Functions: Understanding the Balance from Proliferation to Growth Arrest
  29. Synthesis, Antimalarial, Antileishmanial, and Cytotoxicity Activities and Preliminary In Silico ADMET Studies of 2-(7-Chloroquinolin-4-ylamino)ethyl Benzoate Derivatives
  30. CRISPR/Cas9 bioluminescence-based assay for monitoring CFTR trafficking to the plasma membrane
  31. A Synopsis of Hepatitis C Virus Treatments and Future Perspectives
  32. SARS-CoV-2 Infection in Venezuelan Pediatric Patients—A Single Center Prospective Observational Study
  33. Autoimmunity and Immunodeficiency in Severe SARS-CoV-2 Infection and Prolonged COVID-19
  34. Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage
  35. Innate Immune Response in Hypertension
  36. Synthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2H)-one Derivatives
  37. Effect of tetrahydroquinoline derivatives on the intracellular Ca2+ homeostasis in breast cancer cells (MCF-7) and its relationship with apoptosis.
  38. Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches
  39. Molecular Mechanisms of Chloroquine and Hydroxychloroquine use in Cancer Therapy
  40. Caracasine, an ent-kaurane diterpene with proapoptotic and pro-differentiator activity in human leukaemia cell lines
  41. Cellular Senescence: Molecular Targets, Biomarkers, and Senolytic Drugs
  42. Estudio piloto: análisis y detección de anticuerpos IgM e IgG específicos contra el dominio de unión al receptor de la proteína de la espiga del SARS-CoV-2
  43. Specialized Proresolving Lipid Mediators: A Potential Therapeutic Target for Atherosclerosis
  44. One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy
  45. Effect of Glucocorticosteroids in Diamond-Blackfan Anaemia: Maybe Not as Elusive as It Seems
  46. Overview of Memory NK Cells in Viral Infections: Possible Role in SARS-CoV-2 Infection
  47. Kauranes as Anti-inflammatory and Immunomodulatory Agents: An Overview of In Vitro and In Vivo Effects
  48. The YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises
  49. Assessment of Inflammatory Response and its Resolution in Viral Infection and Rheumatoid Arthritis
  50. Potential Role of Bioactive Lipids in Rheumatoid Arthritis
  51. Importancia de la respuesta inmune celular adaptativa en la infección por SARS-CoV-2
  52. Specialized Pro-Resolving Lipid Mediators: The Future of Chronic Pain Therapy?
  53. Tau secretion and propagation: Perspectives for potential preventive interventions in Alzheimer's disease and other tauopathies
  54. A Brief Analysis of Tissue-Resident NK Cells in Pregnancy and Endometrial Diseases: The Importance of Pharmacologic Modulation
  55. Editorial: Quo Vadis Lipid Mediators – Lipid Mediators Implication in Inflammation and Chronic Inflammatory Diseases
  56. Coronavirus infection: An immunologists' perspective
  57. Synthesis and antimalarial and anticancer evaluation of 7‐chlorquinoline‐4‐thiazoleacetic derivatives containing aryl hydrazide moieties
  58. POTENCIALES OPCIONES TERAPÉUTICAS PARA INFECCIONES POR SARS-CoV 1 Y 2
  59. CFTR Correctors and Antioxidants Partially Normalize Lipid Imbalance but not Abnormal Basal Inflammatory Cytokine Profile in CF Bronchial Epithelial Cells
  60. Quo Vadis Lipid Mediators – Lipid Mediators Implication in Inflammation and Chronic Inflammatory Diseases
  61. Subpoblaciones linfocitarias de pacientes venezolanos infectados con SARS-CoV-2
  62. Importance of miRNA in SARS-CoV2 infection
  63. Functionally Relevant Differences in Plasma Fatty Acid Composition and Expression of Cytotoxic and Inhibitory NK Cell Receptors between Healthy Young and Healthy Elder Adults
  64. Small Natural and Synthetic Molecules for Therapeutic Use
  65. A brief overview of cancer research in the elderly population
  66. The role of essential fatty acids in cystic fibrosis and normalizing effect of fenretinide
  67. Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis
  68. Treatment of allergic asthma with Fenretinide formulation (LAU-7b) downregulates Ormdl3 expression and normalizes ceramides imbalance
  69. Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction
  70. Synthesis and biological activity of 2-[2-(7-chloroquinolin-4-ylthio)-4-methylthiazol-5-yl]-N-phenylacetamide derivatives as antimalarial and cytotoxic agents
  71. Effect of fenretidine on murine asthma model
  72. Pharmacologic Modulation of the Immune Response Against Tumours in the Elderly
  73. New structures as anti malarials and anti cancer drugs
  74. Caracasine acid is a seco kaurene purified from Croton caracasana
  75. Reviw on the importance of long chain fatty acids
  76. Effects of flavonoids and Its Derivatives on Immune Cell Responses
  77. Synthesis, antimalarial, antiproliferative, and apoptotic activities of benzimidazole-5-carboxamide derivatives
  78. Cardiorespiratory responses, nitric oxide production and inflammatory factors in patients with myocardial infarction after rehabilitation
  79. Importance of zona pellucida binding protgein in inflammation
  80. Anti malarial and anti cancer compound
  81. Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside
  82. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells
  83. A Review of Clinical Trials of Belimumab in the Management of Systemic Lupus Erythematosus
  84. Editorial of immunomodulation issue
  85. Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931
  86. Sphingosine inhibits the sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) activity
  87. Inflammatory gene polymorphisms in asthma and chronic obstructive pulmonary disease in Venezuela
  88. Peptide Vaccines for Cancer Therapy
  89. Editorial (Thematic Issue: Vaccines)
  90. Vaccine Therapy Update for Pregnant, Immunocompromised, and Chronic Diseases Patients
  91. Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy
  92. New treatment for asthma
  93. An Overview of Hepatitis C Vaccines
  94. This review refers to the different approaches for vaccine therapy in HIV infection
  95. Importance in unsaturated fatty acids in zoonotic infection
  96. Candidate Markers Associated with the Probability of Future Pulmonary Exacerbations in Cystic Fibrosis Patients
  97. Metabolic Syndrome and Asthma
  98. Surfactant Protein D in Chornic Obstructive Pulmonary Disease (COPD)
  99. Fenretinide Corrects the Imbalance between Omega-6 to Omega-3 Polyunsaturated Fatty Acids and Inhibits Macrophage Inflammatory Mediators via the ERK Pathway
  100. The review focus on the different adjuvants and delivery systems used for diffetent vaccines
  101. Recent Patents in Autophagy and Immune Response
  102. Nitric oxide synthase and its relation to PKC activation
  103. Gene-Metabolite Expression in Blood Can Discriminate Allergen-Induced Isolated Early from Dual Asthmatic Responses
  104. Effect of lycopene administration in cystic fibrosis patients
  105. Biomarkers in Asthma and COPD
  106. Lipid profile analysis in spinal trauma patients shows severe distortion of AA/DHA after injury
  107. Beta 2 adrenergic receptor polymorphisms, at codons 16 and 27, and bronchodilator responses in adult venezuelan asthmatic patients
  108. Cytotoxic effects of fisturalin-3 and 11-deoxyfisturalin-3 on jurkat and u937 cell lines
  109. Perspectives of New Therapies for Endometriosis
  110. 336 The Leukotriene C4 Synthase (A-444C) Promoter Polymorphism in Venezuelan Individuals with Asthma
  111. Role of Beta2 Agonists in Respiratory Medicine with Particular Attention to Novel Patents and Effects on Endocrine System and Immune Response
  112. Inhibitors of Phosphoinositol 3 Kinase and NFκB for the Treatment of Chronic Obstructive Pulmonary Disease
  113. The marine sponge toxin agelasine B increases the intracellular Ca2+ concentration and induces apoptosis in human breast cancer cells (MCF-7)
  114. New pharmacological treatments for patients with chronic obstructive pumonary disease (copd)
  115. Specific activation of human neutrophils by scorpion venom: A flow cytometry assessment
  116. Atherosclerosis risk in SLE is not dependent on macrophage uptake of ox-LDL
  117. Ceramide in Cystic Fibrosis: A Potential New Target for Therapeutic Intervention
  118. Pharmacological Properties of Thalidomide and its Analogues
  119. Fenretinide Promotes Functional Recovery and Tissue Protection after Spinal Cord Contusion Injury in Mice
  120. CD16 cross-linking induces increased expression of CD56 and production of IL-12 in peripheral NK cells
  121. Increased lipid peroxidation and abnormal fatty acid profiles in seminal and blood plasma of normozoospermic males from infertile couples
  122. Cystic Fibrosis Fatty Acid Imbalance Is Linked to Ceramide Deficiency and Corrected by Fenretinide
  123. Pharmacological Modulation of Th17
  124. Serum adipokine levels in patients with systemic lupus erythematosus
  125. Total and biologically active CD154 in patients with SLE
  126. Decreased transcription, expression and function of low-density lipoprotein receptor in leukocytes from patients with systemic lupus erythematosus
  127. Fenretinide prevents the development of osteoporosis in Cftr-KO mice
  128. Abnalysis of the effect of smoking in muscle
  129. Possible role of NFĸB in the embryonic vascular remodeling and the endothelial-mesenchymal transition process
  130. Fenretinide Corrects Newly Found Ceramide Deficiency in Cystic Fibrosis
  131. Nitric Oxide Metabolites and Nitrotyrosine in Asthma and COPD
  132. Toll-Like Receptors, Cytokines and the Immunotherapeutics of Asthma
  133. New Frontiers in the Therapeutic Management of Transplant Rejection
  134. Role of SLC11A1 (formerly NRAMP1) in regulation of signal transduction induced by Toll-like receptor 7 ligands
  135. F.23. Polymorphisms of Toll-Like Receptor 2 and 4 Genes in Asthma and COPD
  136. Skeletal muscle inflammation and nitric oxide in patients with COPD
  137. Inflammation and nitric oxide production in skeletal muscle of type 2 diabetic patients
  138. Interaction of immune complexes isolated from hepatitis C virus-infected individuals with human cell lines
  139. Lipoprotein lipase protects bovine endothelial cells from human NK cytotoxic activity
  140. Expression of CD40/CD40L is important is chicken embryo aorta transdifferentiation
  141. Leptin and leptin receptors during malaria infection in mice
  142. Activity profile in multiple sclerosis: an integrative approach A preliminary report
  143. Expression of surface molecules on eosinophils from patients with persistent allergic rhinitis (PAR), before and after treatment
  144. Clearance of Infection with Mycobacterium bovis BCG in Mice Is Enhanced by Treatment with S28463 (R-848), and Its Efficiency Depends on Expression of Wild-Type Nramp1 (Resistance Allele)
  145. Antihypertensive Treatment Decreased Serum Leptin Levels in Severe Preeclampsia during Pregnancy
  146. Endothelial Cells Scraped from the Luminal Surface of Bovine Pulmonary Artery Give Rise to Nonmuscle Cells
  147. Increased Peroxide Production by Polymorphonuclear Cells of Chronic Hepatitis C Virus-Infected Patients
  148. Expression of low‐density lipoprotein receptors in peripheral blood and tonsil B lymphocytes
  149. Characterization of Local Memory Cells in Stage‐Classified Pulmonary Tuberculosis: Preliminary Observations
  150. Phenotypic difference between Bcgr and Bcgs macrophages is related to differences in protein-kinase-C-dependent signalling
  151. Nitric Oxide in Different Types of Hypertension during Pregnancy
  152. Impaired NK cytotoxicity of NK cells of HCV patients
  153. Secretion of cytokines by natural killer cells primed with interleukin‐2 and stimulated with different lipoproteins
  154. Low density lipoprotein receptor expression and function in human polymorphonuclear leucocytes
  155. Expression and Function of Low-Density Lipoprotein Receptors in CD3−CD16+CD56+Cells: Effect of Interleukin 2
  156. Effects of Different Lipoproteins on the Proliferative Response of Interleukin-2-Activated T Lymphocytes and Large Granular Lymphocytes
  157. Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities
  158. High macrophage lipoprotein lipase expression and secretion are associated in inbred murine strains with susceptibility to atherosclerosis
  159. Kinetics of product inhibition and mechanisms of lipoprotein lipase activation by apolipoprotein C-II
  160. The kinetics of heparin inhibition of the esterase and basal lipase activities of lipoprotein lipase
  161. The effects of bovine serum albumin and oleic acid on rat pancreatic lipase and bovine milk lipoprotein lipase