All Stories

  1. Inflammation, Autoimmunity and Neurodegenerative Diseases, Therapeutics and Beyond
  2. Genetic polymorphism in primary, recurrent pregnancy loss
  3. Antineoplastics for treating Alzheimer's disease and dementia: Evidence from preclinical and observational studies
  4. Autoimmunity and Immunodeficiency in Severe SARS-CoV-2 Infection and Prolonged COVID-19
  5. Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage
  6. Innate Immune Response in Hypertension
  7. Synthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2H)-one Derivatives
  8. Effect of tetrahydroquinoline derivatives on the intracellular Ca2+ homeostasis in breast cancer cells (MCF-7) and its relationship with apoptosis.
  9. Metabolic Reprogramming in Cancer Cells: Emerging Molecular Mechanisms and Novel Therapeutic Approaches
  10. Molecular Mechanisms of Chloroquine and Hydroxychloroquine use in Cancer Therapy
  11. Caracasine, an ent-kaurane diterpene with proapoptotic and pro-differentiator activity in human leukaemia cell lines
  12. Cellular Senescence: Molecular Targets, Biomarkers, and Senolytic Drugs
  13. Estudio piloto: análisis y detección de anticuerpos IgM e IgG específicos contra el dominio de unión al receptor de la proteína de la espiga del SARS-CoV-2
  14. Specialized Proresolving Lipid Mediators: A Potential Therapeutic Target for Atherosclerosis
  15. One-Step Synthesis of Nanoliposomal Copper Diethyldithiocarbamate and Its Assessment for Cancer Therapy
  16. Effect of Glucocorticosteroids in Diamond-Blackfan Anaemia: Maybe Not as Elusive as It Seems
  17. Overview of Memory NK Cells in Viral Infections: Possible Role in SARS-CoV-2 Infection
  18. Kauranes as Anti-inflammatory and Immunomodulatory Agents: An Overview of In Vitro and In Vivo Effects
  19. The YAP/TAZ Signaling Pathway in the Tumor Microenvironment and Carcinogenesis: Current Knowledge and Therapeutic Promises
  20. Assessment of Inflammatory Response and its Resolution in Viral Infection and Rheumatoid Arthritis
  21. Potential Role of Bioactive Lipids in Rheumatoid Arthritis
  22. Importancia de la respuesta inmune celular adaptativa en la infección por SARS-CoV-2
  23. Specialized Pro-Resolving Lipid Mediators: The Future of Chronic Pain Therapy?
  24. Tau secretion and propagation: Perspectives for potential preventive interventions in Alzheimer's disease and other tauopathies
  25. A Brief Analysis of Tissue-Resident NK Cells in Pregnancy and Endometrial Diseases: The Importance of Pharmacologic Modulation
  26. Editorial: Quo Vadis Lipid Mediators – Lipid Mediators Implication in Inflammation and Chronic Inflammatory Diseases
  27. Coronavirus infection: An immunologists' perspective
  28. Synthesis and antimalarial and anticancer evaluation of 7‐chlorquinoline‐4‐thiazoleacetic derivatives containing aryl hydrazide moieties
  29. CFTR Correctors and Antioxidants Partially Normalize Lipid Imbalance but not Abnormal Basal Inflammatory Cytokine Profile in CF Bronchial Epithelial Cells
  30. Quo Vadis Lipid Mediators – Lipid Mediators Implication in Inflammation and Chronic Inflammatory Diseases
  31. Subpoblaciones linfocitarias de pacientes venezolanos infectados con SARS-CoV-2
  32. Importance of miRNA in SARS-CoV2 infection
  33. Functionally Relevant Differences in Plasma Fatty Acid Composition and Expression of Cytotoxic and Inhibitory NK Cell Receptors between Healthy Young and Healthy Elder Adults
  34. Small Natural and Synthetic Molecules for Therapeutic Use
  35. A brief overview of cancer research in the elderly population
  36. The role of essential fatty acids in cystic fibrosis and normalizing effect of fenretinide
  37. Age-Dependent Progression in Lung Pathophysiology can be Prevented by Restoring Fatty Acid and Ceramide Imbalance in Cystic Fibrosis
  38. Treatment of allergic asthma with Fenretinide formulation (LAU-7b) downregulates Ormdl3 expression and normalizes ceramides imbalance
  39. Fenretinide favorably affects mucins (MUC5AC/MUC5B) and fatty acid imbalance in a manner mimicking CFTR-induced correction
  40. Synthesis and biological activity of 2-[2-(7-chloroquinolin-4-ylthio)-4-methylthiazol-5-yl]-N-phenylacetamide derivatives as antimalarial and cytotoxic agents
  41. Effect of fenretidine on murine asthma model
  42. Pharmacologic Modulation of the Immune Response Against Tumours in the Elderly
  43. New structures as anti malarials and anti cancer drugs
  44. Caracasine acid is a seco kaurene purified from Croton caracasana
  45. Reviw on the importance of long chain fatty acids
  46. Effects of flavonoids and Its Derivatives on Immune Cell Responses
  47. Synthesis, antimalarial, antiproliferative, and apoptotic activities of benzimidazole-5-carboxamide derivatives
  48. Cardiorespiratory responses, nitric oxide production and inflammatory factors in patients with myocardial infarction after rehabilitation
  49. Importance of zona pellucida binding protgein in inflammation
  50. Anti malarial and anti cancer compound
  51. Fenretinide differentially modulates the levels of long- and very long-chain ceramides by downregulating Cers5 enzyme: evidence from bench to bedside
  52. Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells
  53. A Review of Clinical Trials of Belimumab in the Management of Systemic Lupus Erythematosus
  54. Editorial of immunomodulation issue
  55. Correction of lung inflammation in a F508del CFTR murine cystic fibrosis model by the sphingosine-1-phosphate lyase inhibitor LX2931
  56. Sphingosine inhibits the sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) activity
  57. Inflammatory gene polymorphisms in asthma and chronic obstructive pulmonary disease in Venezuela
  58. Peptide Vaccines for Cancer Therapy
  59. Editorial (Thematic Issue: Vaccines)
  60. Vaccine Therapy Update for Pregnant, Immunocompromised, and Chronic Diseases Patients
  61. Lycopene improves the distorted ratio between AA/DHA in the seminal plasma of infertile males and increases the likelihood of successful pregnancy
  62. New treatment for asthma
  63. An Overview of Hepatitis C Vaccines
  64. This review refers to the different approaches for vaccine therapy in HIV infection
  65. Importance in unsaturated fatty acids in zoonotic infection
  66. Candidate Markers Associated with the Probability of Future Pulmonary Exacerbations in Cystic Fibrosis Patients
  67. Metabolic Syndrome and Asthma
  68. Surfactant Protein D in Chornic Obstructive Pulmonary Disease (COPD)
  69. Fenretinide Corrects the Imbalance between Omega-6 to Omega-3 Polyunsaturated Fatty Acids and Inhibits Macrophage Inflammatory Mediators via the ERK Pathway
  70. The review focus on the different adjuvants and delivery systems used for diffetent vaccines
  71. Recent Patents in Autophagy and Immune Response
  72. Nitric oxide synthase and its relation to PKC activation
  73. Gene-Metabolite Expression in Blood Can Discriminate Allergen-Induced Isolated Early from Dual Asthmatic Responses
  74. Effect of lycopene administration in cystic fibrosis patients
  75. Biomarkers in Asthma and COPD
  76. Lipid profile analysis in spinal trauma patients shows severe distortion of AA/DHA after injury
  77. Beta 2 adrenergic receptor polymorphisms, at codons 16 and 27, and bronchodilator responses in adult venezuelan asthmatic patients
  78. Cytotoxic effects of fisturalin-3 and 11-deoxyfisturalin-3 on jurkat and u937 cell lines
  79. Perspectives of New Therapies for Endometriosis
  80. 336 The Leukotriene C4 Synthase (A-444C) Promoter Polymorphism in Venezuelan Individuals with Asthma
  81. Role of Beta2 Agonists in Respiratory Medicine with Particular Attention to Novel Patents and Effects on Endocrine System and Immune Response
  82. Inhibitors of Phosphoinositol 3 Kinase and NFκB for the Treatment of Chronic Obstructive Pulmonary Disease
  83. The marine sponge toxin agelasine B increases the intracellular Ca2+ concentration and induces apoptosis in human breast cancer cells (MCF-7)
  84. New pharmacological treatments for patients with chronic obstructive pumonary disease (copd)
  85. Specific activation of human neutrophils by scorpion venom: A flow cytometry assessment
  86. Atherosclerosis risk in SLE is not dependent on macrophage uptake of ox-LDL
  87. Ceramide in Cystic Fibrosis: A Potential New Target for Therapeutic Intervention
  88. Pharmacological Properties of Thalidomide and its Analogues
  89. Fenretinide Promotes Functional Recovery and Tissue Protection after Spinal Cord Contusion Injury in Mice
  90. CD16 cross-linking induces increased expression of CD56 and production of IL-12 in peripheral NK cells
  91. Increased lipid peroxidation and abnormal fatty acid profiles in seminal and blood plasma of normozoospermic males from infertile couples
  92. Cystic Fibrosis Fatty Acid Imbalance Is Linked to Ceramide Deficiency and Corrected by Fenretinide
  93. Pharmacological Modulation of Th17
  94. Serum adipokine levels in patients with systemic lupus erythematosus
  95. Total and biologically active CD154 in patients with SLE
  96. Decreased transcription, expression and function of low-density lipoprotein receptor in leukocytes from patients with systemic lupus erythematosus
  97. Fenretinide prevents the development of osteoporosis in Cftr-KO mice
  98. Abnalysis of the effect of smoking in muscle
  99. Possible role of NFĸB in the embryonic vascular remodeling and the endothelial-mesenchymal transition process
  100. Fenretinide Corrects Newly Found Ceramide Deficiency in Cystic Fibrosis
  101. Nitric Oxide Metabolites and Nitrotyrosine in Asthma and COPD
  102. Toll-Like Receptors, Cytokines and the Immunotherapeutics of Asthma
  103. New Frontiers in the Therapeutic Management of Transplant Rejection
  104. Role of SLC11A1 (formerly NRAMP1) in regulation of signal transduction induced by Toll-like receptor 7 ligands
  105. F.23. Polymorphisms of Toll-Like Receptor 2 and 4 Genes in Asthma and COPD
  106. Skeletal muscle inflammation and nitric oxide in patients with COPD
  107. Inflammation and nitric oxide production in skeletal muscle of type 2 diabetic patients
  108. Interaction of immune complexes isolated from hepatitis C virus-infected individuals with human cell lines
  109. Lipoprotein lipase protects bovine endothelial cells from human NK cytotoxic activity
  110. Expression of CD40/CD40L is important is chicken embryo aorta transdifferentiation
  111. Leptin and leptin receptors during malaria infection in mice
  112. Activity profile in multiple sclerosis: an integrative approach A preliminary report
  113. Expression of surface molecules on eosinophils from patients with persistent allergic rhinitis (PAR), before and after treatment
  114. Clearance of Infection with Mycobacterium bovis BCG in Mice Is Enhanced by Treatment with S28463 (R-848), and Its Efficiency Depends on Expression of Wild-Type Nramp1 (Resistance Allele)
  115. Antihypertensive Treatment Decreased Serum Leptin Levels in Severe Preeclampsia during Pregnancy
  116. Endothelial Cells Scraped from the Luminal Surface of Bovine Pulmonary Artery Give Rise to Nonmuscle Cells
  117. Increased Peroxide Production by Polymorphonuclear Cells of Chronic Hepatitis C Virus-Infected Patients
  118. Expression of low‐density lipoprotein receptors in peripheral blood and tonsil B lymphocytes
  119. Characterization of Local Memory Cells in Stage‐Classified Pulmonary Tuberculosis: Preliminary Observations
  120. Phenotypic difference between Bcgr and Bcgs macrophages is related to differences in protein-kinase-C-dependent signalling
  121. Nitric Oxide in Different Types of Hypertension during Pregnancy
  122. Impaired NK cytotoxicity of NK cells of HCV patients
  123. Secretion of cytokines by natural killer cells primed with interleukin‐2 and stimulated with different lipoproteins
  124. Low density lipoprotein receptor expression and function in human polymorphonuclear leucocytes
  125. Expression and Function of Low-Density Lipoprotein Receptors in CD3−CD16+CD56+Cells: Effect of Interleukin 2
  126. Effects of Different Lipoproteins on the Proliferative Response of Interleukin-2-Activated T Lymphocytes and Large Granular Lymphocytes
  127. Dietary n-3 polyunsaturated fatty acids prevent the development of atherosclerotic lesions in mice. Modulation of macrophage secretory activities
  128. High macrophage lipoprotein lipase expression and secretion are associated in inbred murine strains with susceptibility to atherosclerosis
  129. Kinetics of product inhibition and mechanisms of lipoprotein lipase activation by apolipoprotein C-II
  130. The kinetics of heparin inhibition of the esterase and basal lipase activities of lipoprotein lipase
  131. The effects of bovine serum albumin and oleic acid on rat pancreatic lipase and bovine milk lipoprotein lipase