All Stories

  1. Interpretable Machine Learning Identifies an Emergent Absence Seizure Mechanism

    Article • September 2025, Cold Spring Harbor Laboratory Press

    John Huguenard

  2. Reticular thalamic hyperexcitability drives autism spectrum disorder behaviors in the Cntnap2 model of autism

    Article • Science Advances, August 2025, American Association for the Advancement of Science

    John Huguenard

  3. Actions of the antiseizure drug carbamazepine in the thalamic reticular nucleus: Potential mechanism of aggravating absence seizures

    Article • Proceedings of the National Academy of Sciences, July 2025, Proceedings of the National Academy of Sciences

    John Huguenard

  4. Rhythmic Quakes Shock the Cortical Focus Theory

    Article • Epilepsy Currents, June 2025, SAGE Publications

    John Huguenard

  5. Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

    Article • eLife, April 2025, eLife

    John Huguenard

  6. Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

    Article • eLife, April 2025, eLife

    John Huguenard

  7. Reticular Thalamic Hyperexcitability Drives Autism Spectrum Disorder Behaviors in the Cntnap2 Model of Autism

    Article • March 2025, Cold Spring Harbor Laboratory Press

    John Huguenard

  8. The reuniens thalamus recruits recurrent excitation in the medial prefrontal cortex

    Article • Proceedings of the National Academy of Sciences, March 2025, Proceedings of the National Academy of Sciences

    John Huguenard

  9. Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

    Article • February 2025, eLife

    John Huguenard

  10. Actions of the Anti-Seizure Drug Carbamazepine in the Thalamic Reticular Nucleus: Potential Mechanism of Aggravating Absence Seizures

    Article • February 2025, Cold Spring Harbor Laboratory Press

    John Huguenard

  11. Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

    Article • November 2024, eLife

    John Huguenard

  12. Disrupted Development of the mPFC-Thalamic Circuit in the Mouse Shank3−/−model of Autism

    Article • September 2024, Cold Spring Harbor Laboratory Press

    John Huguenard

  13. Synaptic cell adhesion molecule Cdh6 identifies a class of sensory neurons with novel functions in colonic motility

    Article • August 2024, Cold Spring Harbor Laboratory Press

    John Huguenard

  14. Cross-regional coordination of activity in the human brain during autobiographical self-referential processing

    Article • Proceedings of the National Academy of Sciences, July 2024, Proceedings of the National Academy of Sciences

    John Huguenard

  15. Reuniens thalamus recruits recurrent excitation in medial prefrontal cortex

    Article • June 2024, Cold Spring Harbor Laboratory Press

    John Huguenard

  16. Adult Gene Therapy for Epilepsy in a Model of Angelman Syndrome: Hope or Hype?

    Article • Epilepsy Currents, August 2023, SAGE Publications

    John Huguenard

  17. Cross regional coordination of neural activity in the human brain during autobiographical self-referential processing

    Article • June 2023, Cold Spring Harbor Laboratory Press

    John Huguenard

  18. A CMOS-based highly scalable flexible neural electrode interface

    Article • Science Advances, June 2023, American Association for the Advancement of Science

    John Huguenard

  19. Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy

    Article • eLife, April 2023, eLife

    John Huguenard

  20. A CMOS-based highly scalable flexible neural electrode interface

    Article • November 2022, Cold Spring Harbor Laboratory Press

    John Huguenard

  21. Author Correction: Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin

    Article • Nature Communications, April 2022, Springer Science + Business Media

    John Huguenard

  22. Prefrontal PV interneurons facilitate attention and are linked to attentional dysfunction in a mouse model of absence epilepsy

    Article • March 2022, Cold Spring Harbor Laboratory Press

    John Huguenard

  23. Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin

    Article • Nature Communications, July 2021, Springer Science + Business Media

    John Huguenard

  24. Development and validation of a potent and specific inhibitor for the CLC-2 chloride channel

    Article • Proceedings of the National Academy of Sciences, December 2020, Proceedings of the National Academy of Sciences

    John Huguenard

  25. An Evolving-Dynamic Network Activity Approach to Epileptic Seizure Prediction using Machine Learning

    Article • November 2020, Cold Spring Harbor Laboratory Press

    John Huguenard

  26. Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin

    Article • November 2020, Cold Spring Harbor Laboratory Press

    John Huguenard

  27. Perspective: Is Cortical Hyperexcitability the Only Path to Generalized Absence Epilepsy?

    Article • Epilepsy Currents, October 2020, SAGE Publications

    John Huguenard

  28. Nonlinearities between inhibition and T-type calcium channel activity bidirectionally regulate thalamic oscillations

    Article • eLife, September 2020, eLife

    John Huguenard

  29. Nonlinearities between inhibition and T-type calcium channel activity bidirectionally regulate thalamic network oscillations

    Article • June 2020, Cold Spring Harbor Laboratory Press

    John Huguenard

  30. Thalamic activity patterns unfolding over multiple time scales predict seizure onset in absence epilepsy

    Article • March 2020, Cold Spring Harbor Laboratory Press

    John Huguenard

  31. Current Controversy: Spikes, Bursts, and Synchrony in Generalized Absence Epilepsy: Unresolved Questions Regarding Thalamocortical Synchrony in Absence Epilepsy

    Article • Epilepsy Currents, March 2019, SAGE Publications

    John Huguenard

  32. Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures

    Article • Nature Neuroscience, January 2019, Springer Science + Business Media

    John Huguenard

  33. Anatomically Defined and Functionally Distinct Dorsal Raphe Serotonin Sub-systems

    Article • Cell, October 2018, Elsevier

    John Huguenard

  34. Assembly of functionally integrated human forebrain spheroids

    Article • Nature, April 2017, Springer Science + Business Media

    John Huguenard

  35. Breathing control center neurons that promote arousal in mice

    Article • Science, March 2017, American Association for the Advancement of Science

    John Huguenard

  36. Regulation of Thalamic and Cortical Network Synchrony by Scn8a

    Article • Neuron, March 2017, Elsevier

    John Huguenard

  37. Bidirectional Control of Generalized Epilepsy Networks via Rapid Real-Time Switching of Firing Mode

    Article • Neuron, January 2017, Elsevier

    John Huguenard

  38. Tapping the Brakes: Cellular and Synaptic Mechanisms that Regulate Thalamic Oscillations

    Article • Neuron, November 2016, Elsevier

    John Huguenard

  39. Catching a wave

    Article • eLife, October 2016, eLife

    John Huguenard

  40. Two classes of excitatory synaptic responses in rat thalamic reticular neurons

    Article • Journal of Neurophysiology, September 2016, American Physiological Society

    John Huguenard

  41. LSPS/Optogenetics to Improve Synaptic Connectivity Mapping: Unmasking the Role of Basket Cell-Mediated Feedforward Inhibition

    Article • eNeuro, July 2016, Society for Neuroscience

    John Huguenard

  42. Early postnatal switch in GABAA receptor α-subunits in the reticular thalamic nucleus

    Article • Journal of Neurophysiology, March 2016, American Physiological Society

    John Huguenard

  43. Enhanced phasic GABA inhibition during the repair phase of stroke: a novel therapeutic target

    Article • Brain, December 2015, Oxford University Press (OUP)

    John Huguenard

  44. Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood–brain barrier dysfunction

    Article • Neurobiology of Disease, June 2015, Elsevier

    John Huguenard

  45. Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

    Article • Nature Chemical Biology, May 2015, Springer Science + Business Media

    John Huguenard

  46. Electrical synapses connect a network of gonadotropin releasing hormone neurons in a cichlid fish

    Article • Proceedings of the National Academy of Sciences, March 2015, Proceedings of the National Academy of Sciences

    John Huguenard

  47. Microcircuits and their interactions in epilepsy: is the focus out of focus?

    Article • Nature Neuroscience, February 2015, Springer Science + Business Media

    John Huguenard

  48. Seizing upon Mechanisms for Impaired Consciousness

    Article • Neuron, February 2015, Elsevier

    John Huguenard

  49. Cholinergic Control of Gamma Power in the Midbrain Spatial Attention Network

    Article • Journal of Neuroscience, January 2015, Society for Neuroscience

    John Huguenard

  50. Optogenetics and Epilepsy: Past, Present and Future

    Article • Epilepsy Currents, January 2015, SAGE Publications

    John Huguenard

  51. Endozepines

    Article • January 2015, Elsevier

    John Huguenard

  52. Attentional flexibility in the thalamus: now we're getting SOMwhere

    Article • Nature Neuroscience, December 2014, Springer Science + Business Media

    John Huguenard

  53. Frequency-Dependent, Cell Type-Divergent Signaling in the Hippocamposeptal Projection

    Article • Journal of Neuroscience, August 2014, Society for Neuroscience

    John Huguenard

  54. Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex

    Article • Cerebral Cortex, July 2014, Oxford University Press (OUP)

    John Huguenard

  55. Parallel Midbrain Microcircuits Perform Independent Temporal Transformations

    Article • Journal of Neuroscience, June 2014, Society for Neuroscience

    John Huguenard

  56. A Local Glutamate-Glutamine Cycle Sustains Synaptic Excitatory Transmitter Release

    Article • Neuron, February 2014, Elsevier

    John Huguenard

  57. Spatially Reciprocal Inhibition of Inhibition within a Stimulus Selection Network in the Avian Midbrain

    Article • PLOS One, January 2014, PLOS

    John Huguenard

  58. Modulation of Short-Term Plasticity in the Corticothalamic Circuit by Group III Metabotropic Glutamate Receptors

    Article • Journal of Neuroscience, January 2014, Society for Neuroscience

    John Huguenard

  59. Astrocytes potentiate GABAergic transmission in the thalamic reticular nucleus via endozepine signaling

    Article • Proceedings of the National Academy of Sciences, November 2013, Proceedings of the National Academy of Sciences

    John Huguenard

  60. Sniffer patch laser uncaging response (SPLURgE): an assay of regional differences in allosteric receptor modulation and neurotransmitter clearance

    Article • Journal of Neurophysiology, October 2013, American Physiological Society

    John Huguenard

  61. Endogenous Positive Allosteric Modulation of GABAA Receptors by Diazepam binding inhibitor

    Article • Neuron, June 2013, Elsevier

    John Huguenard

  62. Reemerging role of cable properties in action potential initiation

    Article • Proceedings of the National Academy of Sciences, February 2013, Proceedings of the National Academy of Sciences

    John Huguenard

  63. Sleep and Epilepsy: A Summary of the 2011 Merritt-Putnam Symposium

    Article • Epilepsy Currents, January 2013, SAGE Publications

    John Huguenard

  64. Glutamate biosensor imaging reveals dysregulation of glutamatergic pathways in a model of developmental cortical malformation

    Article • Neurobiology of Disease, January 2013, Elsevier

    John Huguenard

  65. Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

    Article • Nature Neuroscience, November 2012, Springer Science + Business Media

    John Huguenard

  66. A call for transparent reporting to optimize the predictive value of preclinical research

    Article • Nature, October 2012, Springer Science + Business Media

    Professor Malcolm R Macleod, John Huguenard

  67. Mechanism for Hypocretin-mediated sleep-to-wake transitions

    Article • Proceedings of the National Academy of Sciences, September 2012, Proceedings of the National Academy of Sciences

    John Huguenard

  68. Enhanced NMDA Receptor-Dependent Thalamic Excitation and Network Oscillations in Stargazer Mice

    Article • Journal of Neuroscience, August 2012, Society for Neuroscience

    John Huguenard

  69. R U OK? the Novel Therapeutic Potential of R Channels in Epilepsy

    Article • Epilepsy Currents, March 2012, SAGE Publications

    John Huguenard

  70. Gamma Oscillations Are Generated Locally in an Attention-Related Midbrain Network

    Article • Neuron, February 2012, Elsevier

    John Huguenard

  71. Increased Excitatory Synaptic Input to Granule Cells from Hilar and CA3 Regions in a Rat Model of Temporal Lobe Epilepsy

    Article • Journal of Neuroscience, January 2012, Society for Neuroscience

    John Huguenard

  72. Neocortical excitation/inhibition balance in information processing and social dysfunction

    Article • Nature, July 2011, Springer Science + Business Media

    John Huguenard

  73. Influence of a Subtype of Inhibitory Interneuron on Stimulus-Specific Responses in Visual Cortex

    Article • Cerebral Cortex, June 2011, Oxford University Press (OUP)

    John Huguenard

  74. Martinotti Cells: Community Organizers

    Article • Neuron, March 2011, Elsevier

    John Huguenard

  75. Mechanisms of excitability in the thalamocortical circuit

    Article • Epilepsia, December 2010, Wiley

    John Huguenard

  76. Differential effects of Na+–K+ ATPase blockade on cortical layer V neurons

    Article • The Journal of Physiology, November 2010, Wiley

    John Huguenard

  77. Astrocytes as Gatekeepers of GABABReceptor Function

    Article • Journal of Neuroscience, November 2010, Society for Neuroscience

    John Huguenard

  78. Desynchronization of Neocortical Networks by Asynchronous Release of GABA at Autaptic and Synaptic Contacts from Fast-Spiking Interneurons

    Article • PLoS Biology, September 2010, PLOS

    John Huguenard

  79. Reorganization of Inhibitory Synaptic Circuits in Rodent Chronically Injured Epileptogenic Neocortex

    Article • Cerebral Cortex, September 2010, Oxford University Press (OUP)

    John Huguenard

  80. Focal Cortical Infarcts Alter Intrinsic Excitability and Synaptic Excitation in the Reticular Thalamic Nucleus

    Article • Journal of Neuroscience, April 2010, Society for Neuroscience

    John Huguenard

  81. Enhanced Infragranular and Supragranular Synaptic Input onto Layer 5 Pyramidal Neurons in a Rat Model of Cortical Dysplasia

    Article • Cerebral Cortex, March 2010, Oxford University Press (OUP)

    John Huguenard

  82. Glutamine Is Required for Persistent Epileptiform Activity in the Disinhibited Neocortical Brain Slice

    Article • Journal of Neuroscience, January 2010, Society for Neuroscience

    John Huguenard

  83. Maintenance of Thalamic Epileptiform Activity Depends on the Astrocytic Glutamate-Glutamine Cycle

    Article • Journal of Neurophysiology, November 2009, American Physiological Society

    John Huguenard

  84. Modeling Voltage-Dependent Channels

    Article • September 2009, The MIT Press

    John Huguenard

  85. Resting Our Cortices by Going DOWN to Sleep

    Article • Neuron, September 2009, Elsevier

    John Huguenard

  86. Who let the spikes out?

    Article • Nature Neuroscience, August 2009, Springer Science + Business Media

    John Huguenard

  87. Synergistic Roles of GABAA Receptors and SK Channels in Regulating Thalamocortical Oscillations

    Article • Journal of Neurophysiology, July 2009, American Physiological Society

    John Huguenard

  88. Robust Short-Latency Perisomatic Inhibition onto Neocortical Pyramidal Cells Detected by Laser-Scanning Photostimulation

    Article • Journal of Neuroscience, June 2009, Society for Neuroscience

    John Huguenard

  89. Neurons that Fire Together Also Conspire Together: Is Normal Sleep Circuitry Hijacked to Generate Epilepsy?

    Article • Neuron, June 2009, Elsevier

    John Huguenard

  90. A gain in GABA A receptor synaptic strength in thalamus reduces oscillatory activity and absence seizures

    Article • Proceedings of the National Academy of Sciences, May 2009, Proceedings of the National Academy of Sciences

    John Huguenard

  91. Sequential Changes in AMPA Receptor Targeting in the Developing Neocortical Excitatory Circuit

    Article • Journal of Neuroscience, December 2008, Society for Neuroscience

    John Huguenard

  92. The Endocannabinoid 2-Arachidonoylglycerol Is Responsible for the Slow Self-Inhibition in Neocortical Interneurons

    Article • Journal of Neuroscience, December 2008, Society for Neuroscience

    John Huguenard

  93. Normal sleep homeostasis and lack of epilepsy phenotype in GABAA receptor α3 subunit-knockout mice

    Article • Neuroscience, June 2008, Elsevier

    John Huguenard

  94. Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4

    Article • Human Molecular Genetics, March 2008, Oxford University Press (OUP)

    John Huguenard

  95. Imaging of glutamate in brain slices using FRET sensors

    Article • Journal of Neuroscience Methods, March 2008, Elsevier

    Professor Wolf B Frommer, John Huguenard

  96. Intrinsic Excitability of Cholinergic Neurons in the Rat Parabigeminal Nucleus

    Article • Journal of Neurophysiology, December 2007, American Physiological Society

    John Huguenard

  97. GABA Affinity Shapes IPSCs in Thalamic Nuclei

    Article • Journal of Neuroscience, July 2007, Society for Neuroscience

    John Huguenard

  98. Thalamic synchrony and dynamic regulation of global forebrain oscillations

    Article • Trends in Neurosciences, July 2007, Elsevier

    John Huguenard

  99. PKC and polyamine modulation of GluR2‐deficient AMPA receptors in immature neocortical pyramidal neurons of the rat

    Article • The Journal of Physiology, May 2007, Wiley

    John Huguenard

  100. Gender and age differences in expression of GABAA receptor subunits in rat somatosensory thalamus and cortex in an absence epilepsy model

    Article • Neurobiology of Disease, March 2007, Elsevier

    John Huguenard

  101. Giant Spontaneous Depolarizing Potentials in the Developing Thalamic Reticular Nucleus

    Article • Journal of Neurophysiology, March 2007, American Physiological Society

    John Huguenard

  102. Recurrent Circuits in Layer II of Medial Entorhinal Cortex in a Model of Temporal Lobe Epilepsy

    Article • Journal of Neuroscience, February 2007, Society for Neuroscience

    John Huguenard

  103. Modulation of epileptiform activity by glutamine and system A transport in a model of post-traumatic epilepsy

    Article • Neurobiology of Disease, February 2007, Elsevier

    Anita E Bandrowski, John Huguenard

  104. NPY signaling through Y1 receptors modulates thalamic oscillations

    Article • Peptides, February 2007, Elsevier

    John Huguenard

  105. A Thalamic Sleep Tonic

    Article • Epilepsy Currents, September 2006, SAGE Publications

    John Huguenard

  106. Distinct Electrical and Chemical Connectivity Maps in the Thalamic Reticular Nucleus: Potential Roles in Synchronization and Sensation

    Article • Journal of Neuroscience, August 2006, Society for Neuroscience

    John Huguenard

  107. Electrophysiological Classification of Somatostatin-Positive Interneurons in Mouse Sensorimotor Cortex

    Article • Journal of Neurophysiology, August 2006, American Physiological Society

    John Huguenard

  108. Selective changes in thalamic and cortical GABAA receptor subunits in a model of acquired absence epilepsy in the rat

    Article • Neuropharmacology, July 2006, Elsevier

    John Huguenard

  109. Chronic Valproic Acid Treatment Triggers Increased Neuropeptide Y Expression and Signaling in Rat Nucleus Reticularis Thalami

    Article • Journal of Neuroscience, June 2006, Society for Neuroscience

    John Huguenard

  110. Enhanced Excitatory Synaptic Connectivity in Layer V Pyramidal Neurons of Chronically Injured Epileptogenic Neocortex in Rats

    Article • Journal of Neuroscience, May 2006, Society for Neuroscience

    John Huguenard

  111. Intrinsic and Synaptic Dynamics Interact to Generate Emergent Patterns of Rhythmic Bursting in Thalamocortical Neurons

    Article • Journal of Neuroscience, April 2006, Society for Neuroscience

    John Huguenard

  112. Fast IPSCs in rat thalamic reticular nucleus require the GABAA receptor β1 subunit

    Article • The Journal of Physiology, April 2006, Wiley

    John Huguenard

  113. Barrel Cortex Microcircuits: Thalamocortical Feedforward Inhibition in Spiny Stellate Cells Is Mediated by a Small Number of Fast-Spiking Interneurons

    Article • Journal of Neuroscience, January 2006, Society for Neuroscience

    John Huguenard

  114. Enhancement of Spike-Timing Precision by Autaptic Transmission in Neocortical Inhibitory Interneurons

    Article • Neuron, January 2006, Elsevier

    John Huguenard

  115. Thalamic, Thalamocortical, and Corticocortical Models of Epilepsy with an Emphasis on Absence Seizures

    Article • January 2006, Elsevier

    John Huguenard

  116. Inhibitory coupling specifically generates emergent gamma oscillations in diverse cell types

    Article • Proceedings of the National Academy of Sciences, December 2005, Proceedings of the National Academy of Sciences

    John Huguenard

  117. Reorganization of barrel circuits leads to thalamically-evoked cortical epileptiform activity

    Article • Thalamus & Related Systems, December 2005, Cambridge University Press

    John Huguenard

  118. Modulation of neocortical interneurons: extrinsic influences and exercises in self-control

    Article • Trends in Neurosciences, November 2005, Elsevier

    John Huguenard

  119. Polyamines Modulate AMPA Receptor–Dependent Synaptic Responses in Immature Layer V Pyramidal Neurons

    Article • Journal of Neurophysiology, May 2005, American Physiological Society

    John Huguenard

  120. Impaired Cl−Extrusion in Layer V Pyramidal Neurons of Chronically Injured Epileptogenic Neocortex

    Article • Journal of Neurophysiology, April 2005, American Physiological Society

    John Huguenard

  121. Long-lasting self-inhibition of neocortical interneurons mediated by endocannabinoids

    Article • Nature, September 2004, Springer Science + Business Media

    John Huguenard

  122. T-Channel Defects in Patients with Childhood Absence Epilepsy

    Article • Epilepsy Currents, January 2004, SAGE Publications

    John Huguenard

  123. Corrigenda

    Article • Journal of Neurophysiology, August 2003, American Physiological Society

    John Huguenard

  124. Neurotransmitter Supply and Demand in Epilepsy

    Article • Epilepsy Currents, March 2003, SAGE Publications

    John Huguenard

  125. Actions of U-92032, a T-Type Ca2+ Channel Antagonist, Support a Functional Linkage Between I T and Slow Intrathalamic Rhythms

    Article • Journal of Neurophysiology, January 2003, American Physiological Society

    John Huguenard

  126. Differential modulation of synaptic transmission by neuropeptide Y in rat neocortical neurons

    Article • Proceedings of the National Academy of Sciences, December 2002, Proceedings of the National Academy of Sciences

    John Huguenard

  127. Baseline Glutamate Levels Affect Group I and II mGluRs in Layer V Pyramidal Neurons of Rat Sensorimotor Cortex

    Article • Journal of Neurophysiology, November 2002, American Physiological Society

    Anita E Bandrowski, John Huguenard

  128. Prolactin-releasing peptide (PrRP) promotes awakening and suppresses absence seizures

    Article • Neuroscience, September 2002, Elsevier

    John Huguenard

  129. Reciprocal inhibition controls the oscillatory state in thalamic networks

    Article • Neurocomputing, June 2002, Elsevier

    John Huguenard

  130. Block of T -Type Ca2+ Channels Is an Important Action of Succinimide Antiabsence Drugs

    Article • Epilepsy Currents, March 2002, SAGE Publications

    John Huguenard

  131. Resilient RTN Fast Spiking in Kv3.1 Null Mice Suggests Redundancy in the Action Potential Repolarization Mechanism

    Article • Journal of Neurophysiology, March 2002, American Physiological Society

    John Huguenard

  132. Sodium Channels

    Article • Neuron, February 2002, Elsevier

    John Huguenard

  133. It Takes T to Tango

    Article • Neuron, July 2001, Elsevier

    John Huguenard

  134. The role of H-current in regulating strength and frequency of thalamic network oscillations

    Article • Thalamus & Related Systems, June 2001, Cambridge University Press

    John Huguenard

  135. Clonazepam suppresses oscillations in rat thalamic slices

    Article • Neurocomputing, June 2001, Elsevier

    John Huguenard

  136. Differential regulation of GABA release and neuronal excitability mediated by neuropeptide Y1 and Y2 receptors in rat thalamic neurons

    Article • The Journal of Physiology, February 2001, Wiley

    John Huguenard

  137. Neuropeptide Y receptors differentially modulate G‐protein‐activated inwardly rectifying K+ channels and high‐voltage‐activated Ca2+ channels in rat thalamic neurons

    Article • The Journal of Physiology, February 2001, Wiley

    John Huguenard

  138. Which Formalism to Use for Modeling Voltage- Dependent Conductances?

    Article • November 2000, Taylor & Francis

    John Huguenard

  139. Nonlinear Thermodynamic Models of Voltage-Dependent Currents

    Article • Journal of Computational Neuroscience, November 2000, Springer Science + Business Media

    John Huguenard

  140. Reliability of axonal propagation: The spike doesn't stop here

    Article • Proceedings of the National Academy of Sciences, August 2000, Proceedings of the National Academy of Sciences

    John Huguenard

  141. Circuit Mechanisms of Spike‐Wave Discharge: Are There Similar Underpinnings for Centrotemporal Spikes?

    Article • Epilepsia, August 2000, Wiley

    John Huguenard

  142. Reciprocal inhibitory connections produce desynchronizing phase lags during intrathalamic oscillations

    Article • Neurocomputing, June 2000, Elsevier

    John Huguenard

  143. Long-range connections synchronize rather than spread intrathalamic oscillatory activity: Computational modeling and in vitro electrophysiology

    Article • Neurocomputing, June 1999, Elsevier

    John Huguenard

  144. Reciprocal Inhibitory Connections and Network Synchrony in the Mammalian Thalamus

    Article • Science, January 1999, American Association for the Advancement of Science

    John Huguenard

  145. Low-voltage-activated (T-type) calcium-channel genes identified

    Article • Trends in Neurosciences, November 1998, Elsevier

    John Huguenard

  146. Cholinergic Switching Within Neocortical Inhibitory Networks

    Article • Science, August 1998, American Association for the Advancement of Science

    John Huguenard

  147. GABAA receptor‐mediated currents in interneurons and pyramidal cells of rat visual cortex

    Article • The Journal of Physiology, February 1998, Wiley

    John Huguenard

  148. Dendritic Calcium Currents in Thalamic Relay Cells

    Article • January 1998, Springer Science + Business Media

    John Huguenard

  149. Nucleus reticularis neurons mediate diverse inhibitory effects in thalamus

    Article • Proceedings of the National Academy of Sciences, August 1997, Proceedings of the National Academy of Sciences

    John Huguenard

  150. γ-Aminobutyric acid type B receptor-dependent burst-firing in thalamic neurons: A dynamic clamp study

    Article • Proceedings of the National Academy of Sciences, November 1996, Proceedings of the National Academy of Sciences

    John Huguenard

  151. Low-Threshold Calcium Currents in Central Nervous System Neurons

    Article • Annual Review of Physiology, October 1996, Annual Reviews

    John Huguenard

  152. Heterogeneous axonal arborizations of rat thalamic reticular neurons in the ventrobasal nucleus

    Article • The Journal of Comparative Neurology, March 1996, Wiley

    John Huguenard

  153. Heterogeneous axonal arborizations of rat thalamic reticular neurons in the ventrobasal nucleus

    Article • The Journal of Comparative Neurology, March 1996, Wiley

    John Huguenard

  154. Low-Threshold Calcium Currents in Central Nervous System Neurons

    Article • Annual Review of Physiology, January 1996, Annual Reviews

    John Huguenard

  155. A model of spike initiation in neocortical pyramidal neurons

    Article • Neuron, December 1995, Elsevier

    John Huguenard

  156. Thalamocortical Interactions

    Article • October 1995, Oxford University Press (OUP)

    John Huguenard

  157. Purinergic inhibition of GABA and glutamate release in the thalamus: Implications for thalamic network activity

    Article • Neuron, October 1995, Elsevier

    John Huguenard

  158. 32. In vitro studies of intrinsic and synaptic mechanisms underlying slow (3 Hz) oscillations in the rat thalamus

    Article • Journal of Neuroscience Methods, April 1994, Elsevier

    John Huguenard

  159. Neurotransmitter Control of Neocortical Neuronal Activity and Excitability

    Article • Cerebral Cortex, January 1993, Oxford University Press (OUP)

    John Huguenard

  160. Determination of State-Dependent Processing in Thalamus by Single Neuron Properties and Neuromodulators

    Article • January 1992, Elsevier

    John Huguenard

  161. Mechanism of Block of Thalamic T-Type Ca2+ Channels by Petit Mal Anticonvulsants

    Article • January 1991, Springer Science + Business Media

    John Huguenard

  162. Patch-Clamp Studies of Voltage-Gated Currents in Identified Neurons of the Rat Cerebral Cortex

    Article • Cerebral Cortex, January 1991, Oxford University Press (OUP)

    John Huguenard

  163. Properties of the Low-Threshold Calcium Current in Thalamic Relay Neurons: Recovery from Inactivation in Relation to the Control of Repetitive Burst Generation

    Article • January 1991, Springer Science + Business Media

    John Huguenard

  164. Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: GABA current blockade

    Article • British Journal of Pharmacology, August 1990, Wiley

    John Huguenard

  165. Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: calcium current reduction

    Article • British Journal of Pharmacology, August 1990, Wiley

    John Huguenard

  166. Cellular Actions of Petit Mal Anticonvulsants: Implication of Thalamic Low-Threshold Calcium Current in Generation of Spike-Wave Discharge

    Article • January 1990, Springer Science + Business Media

    John Huguenard

  167. Physiology of Thalamic Relay Neurons: Properties of Calcium Currents Involved in Burst-Firing

    Article • January 1990, Springer Science + Business Media

    John Huguenard

  168. Characterization of ethosuximide reduction of low‐threshold calcium current in thalamic neurons

    Article • Annals of Neurology, June 1989, Wiley

    John Huguenard

  169. Sodium channels in dendrites of rat cortical pyramidal neurons.

    Article • Proceedings of the National Academy of Sciences, April 1989, Proceedings of the National Academy of Sciences

    John Huguenard

  170. Specific petit mal anticonvulsants reduce calcium currents in thalamic neurons

    Article • Neuroscience Letters, March 1989, Elsevier

    John Huguenard

  171. Development of GABA responsiveness in embryonic turtle cortical neurons

    Article • Neuroscience Letters, July 1988, Elsevier

    John Huguenard

  172. Role of Ornithine Decarboxylase in Cardiac Growth and Hypertrophy

    Article • Science, November 1980, American Association for the Advancement of Science

    John Huguenard

  173. Article • PLOS

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  174. Article • PLOS

    John Huguenard

  175. Article • PLOS

    John Huguenard