Prof. John W Holloway

All Stories

1. 
   Highlights from the 2025 Symposium of the Collegium Internationale Allergologicum

   Article • Journal of Allergy and Clinical Immunology, August 2026, Elsevier

   Prof. John W Holloway

2. 
   Familial associations of lung function between parents, offspring and siblings: a two-generation study of the ECRHS and RHINESSA cohorts

   Article • Thorax, July 2026, BMJ

   Prof. John W Holloway

3. 
   Joint modelling of wheeze and lung function from childhood to early adulthood: four population-based birth cohorts

   Article • EClinicalMedicine, June 2026, Elsevier

   Prof. John W Holloway

4. 
   DNA Methylation at Birth Showing Age-Specific Association with Atopy in Children: A Prospective Longitudinal Study

   Article • Epigenomes, May 2026, MDPI AG

   Prof. John W Holloway

5. 
   Predicting Lung Function from Voice Recordings Using Machine Learning: An Optimised Approach

   Article • May 2026, IOS Press

   Prof. John W Holloway

6. 
   Epigenome-Wide DNA Methylation Levels During Pregnancy: Associations with Parity Across Diverse Populations

   Article • Epigenomes, May 2026, MDPI AG

   Prof. John W Holloway

7. 
   HiFi long-read RNA sequencing enhances clinical diagnostics in rare disorders

   Article • European Journal of Human Genetics, March 2026, Springer Science + Business Media

   Prof. John W Holloway

8. 
   Breastfeeding association with DNA methylation in the pregnancy and childhood epigenetics (PACE) consortium

   Article • Clinical Epigenetics, February 2026, Springer Science + Business Media

   Prof. John W Holloway, Jari Lahti

9. 
   Meta-analysis of genome-wide association studies of food allergy and IgE sensitization

   Article • Journal of Allergy and Clinical Immunology, February 2026, Elsevier

   Prof. John W Holloway

10. 
    Clustering lung function and symptom profiles for asthma risk stratification

    Article • Scientific Reports, December 2025, Springer Science + Business Media

    Prof. John W Holloway

11. 
    Immune transcriptomic differences in paediatric patients with SARS-CoV-2 compared to other lower respiratory tract infections

    Article • November 2025, Cold Spring Harbor Laboratory Press

    Prof. John W Holloway

12. 
    Lung function epigenetic markers across the lifespan

    Article • September 2025, European Respiratory Society (ERS)

    Prof. John W Holloway

13. 
    Parental smoke exposure before age 15 years and offspring asthma trajectories from ages 7 to 53 years

    Article • ERJ Open Research, September 2025, European Respiratory Society (ERS)

    Prof. John W Holloway

14. 
    Paternal prepubertal passive smoke exposure is related to impaired lung function trajectories from childhood to middle age in their offspring

    Article • Thorax, September 2025, BMJ

    Prof. John W Holloway

15. 
    Genetic characterization of preschool wheeze phenotypes

    Article • Journal of Allergy and Clinical Immunology, August 2025, Elsevier

    Prof. John W Holloway

16. 
    HiFi Long-Read RNA Sequencing Enhances Clinical Diagnostics in Rare Disorders

    Article • July 2025, Springer Science + Business Media

    Prof. John W Holloway

17. 
    Trends in DNA Methylation over Time Between Parous and Nulliparous Young Women

    Article • Epigenomes, July 2025, MDPI AG

    Prof. John W Holloway

18. 
    Patterns of Respiratory Symptoms and Asthma Diagnosis in School‐Age Children: Three Birth Cohorts

    Article • Allergy, June 2025, Wiley

    Professor Adnan Custovic, Prof. John W Holloway

19. 
    Gene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies

    Article • Allergy, June 2025, Wiley

    Prof. John W Holloway

20. 
    Exploring geographic differences in IgE response through network and manifold analyses

    Article • Journal of Allergy and Clinical Immunology, June 2025, Elsevier

    Prof. John W Holloway

21. 
    Boys who are overweight as teenagers risk passing on harmful epigenetic traits to future children.

    Article • Communications Biology, May 2025, Springer Science + Business Media

    Prof. John W Holloway

22. 
    Maternal asthma and newborn DNA methylation

    Article • Clinical Epigenetics, May 2025, Springer Science + Business Media

    Prof. John W Holloway

23. 
    The mutation burden of narrowband ultraviolet B phototherapy (NB-UVB) in human skin; relevance to NB-UVB lifetime exposures and skin cancer surveillance

    Article • British Journal of Dermatology, May 2025, Oxford University Press (OUP)

    Prof. John W Holloway

24. 
    Advancing Pediatric and Longitudinal DNA Methylation Studies with CellsPickMe, an Integrated Blood Cell Deconvolution Method

    Article • April 2025, Cold Spring Harbor Laboratory Press

    Prof. John W Holloway

25. 
    Defining the Blood Cytokine Profile in Asthma to Understand Asthma Heterogeneity

    Article • Immunity Inflammation and Disease, March 2025, Wiley

    Prof. John W Holloway

26. 
    Trajectories of airflow limitation from childhood to early adulthood: an analysis of six population-based birth cohorts

    Article • The Lancet Child & Adolescent Health, March 2025, Elsevier

    Prof. John W Holloway

27. 
    Gene-environment interaction analysis in atopic eczema: evidence from large population datasets and modelling in vitro

    Article • January 2025, Cold Spring Harbor Laboratory Press

    Prof. John W Holloway

28. 
    DNA methylation at birth and IgE trajectories from birth to adolescence, different patterns between White and Asian

    Article • Epigenomics, January 2025, Taylor & Francis

    Prof. John W Holloway

29. 
    Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium

    Article • Science Advances, November 2024, American Association for the Advancement of Science

    Prof. John W Holloway

30. 
    Uplift of genetic diagnosis of rare respiratory disease using airway epithelium transcriptome analysis

    Article • Human Molecular Genetics, November 2024, Oxford University Press (OUP)

    Prof. John W Holloway

31. 
    Exploring the genetics of airflow limitation in lung function across the lifespan – a polygenic risk score study

    Article • EClinicalMedicine, September 2024, Elsevier

    Prof. John W Holloway

32. 
    Intergenerational association of DNA methylation between parents and offspring

    Article • Scientific Reports, August 2024, Springer Science + Business Media

    Prof. John W Holloway

33. 
    Tailored antisense oligonucleotides designed to correct aberrant splicing reveal actionable groups of mutations for rare genetic disorders

    Article • Experimental & Molecular Medicine, August 2024, Springer Science + Business Media

    Prof. John W Holloway

34. 
    Association of psoriasis with allergic multimorbidity of asthma, rhinitis, and eczema among adolescents: a cross-sectional study

    Article • Allergy Asthma & Clinical Immunology, July 2024, Springer Science + Business Media

    Prof. John W Holloway

35. 
    Lung function trajectories from school age to adulthood and their relationship with markers of cardiovascular disease risk

    Article • Thorax, May 2024, BMJ

    Prof. John W Holloway

36. 
    Assessing the effect of childbearing on blood DNA methylation through comparison of parous and nulliparous females

    Article • Epigenetics Communications, April 2024, Springer Science + Business Media

    Prof. John W Holloway

37. 
    Lung-function trajectories: relevance and implementation in clinical practice

    Article • The Lancet, April 2024, Elsevier

    Prof. John W Holloway

38. 
    A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation

    Article • Communications Biology, January 2024, Springer Science + Business Media

    Prof. John W Holloway, Jari Lahti

39. 
    Obstructive and restrictive spirometry from school age to adulthood: three birth cohort studies

    Article • EClinicalMedicine, January 2024, Elsevier

    Prof. John W Holloway

40. 
    Genetic and Epigenetic Associations with Pre–Chronic Obstructive Pulmonary Disease Lung Function Trajectories

    Article • American Review of Respiratory Disease, November 2023, American Thoracic Society

    Prof. John W Holloway

41. 
    Identification of eczema clusters and their association with filaggrin and atopic comorbidities: analysis of five birth cohorts

    Article • British Journal of Dermatology, November 2023, Oxford University Press (OUP)

    Prof. John W Holloway

42. 
    European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

    Article • Nature Communications, October 2023, Springer Science + Business Media

    Prof. John W Holloway

43. 
    Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude

    Article • Clinical Epigenetics, September 2023, Springer Science + Business Media

    Prof. John W Holloway, Jari Lahti

44. 
    Boys who smoke in their early teens risk passing on harmful epigenetic traits to future children

    Article • Clinical Epigenetics, August 2023, Springer Science + Business Media

    Prof. John W Holloway

45. 
    The association of DNA methylation at birth with adolescent asthma is mediated by atopy

    Article • Clinical & Experimental Allergy, August 2023, Wiley

    Prof. John W Holloway

46. 
    Polymorphisms in Glutathione S-Transferase (GST) Genes Modify the Effect of Exposure to Maternal Smoking Metabolites in Pregnancy and Offspring DNA Methylation

    Article • Genes, August 2023, MDPI AG

    Prof. John W Holloway

47. 
    Current state and prospects of artificial intelligence in allergy

    Article • Allergy, August 2023, Wiley

    Prof. John W Holloway

48. 
    Defusing the legal and ethical minefield of epigenetic applications in the military, defense, and security context

    Article • Journal of Law and the Biosciences, July 2023, Oxford University Press (OUP)

    Prof. John W Holloway

49. 
    Genetic Associates of Childhood Wheezing Phenotypes Identified

    Article • eLife, May 2023, eLife

    Prof. John W Holloway

50. 
    Gene Expression in Cord Blood and Tuberculosis in Early Childhood: A Nested Case-Control Study in a South African Birth Cohort

    Article • Clinical Infectious Diseases, May 2023, Oxford University Press (OUP)

    Prof. John W Holloway

51. 
    Current state and prospects of artificial intelligence in allergy

    Article • April 2023, Authorea, Inc.

    Prof. John W Holloway, Professor Adnan Custovic

52. 
    A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifiesANXA1as a susceptibility locus for persistent wheezing

    Article • March 2023, Cold Spring Harbor Laboratory Press

    Prof. John W Holloway

53. 
    Preconception origins of asthma, allergies and lung function: The influence of previous generations on the respiratory health of our children

    Article • Journal of Internal Medicine, March 2023, Wiley

    Prof. John W Holloway

54. 
    Fathers’ preconception smoking and offspring DNA methylation: A two generation study

    Article • January 2023, Cold Spring Harbor Laboratory Press

    Prof. John W Holloway

55. 
    Eczema among adolescents in Kuwait: Prevalence, severity, sleep disturbance, antihistamine use, and risk factors

    Article • World Allergy Organization Journal, January 2023, Elsevier

    Prof. John W Holloway

56. 
    Evolution of Eczema, Wheeze, and Rhinitis from Infancy to Early Adulthood: Four Birth Cohort Studies

    Article • American Review of Respiratory Disease, October 2022, American Thoracic Society

    Professor Adnan Custovic, Prof. John W Holloway

57. 
    European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation

    Article • October 2022, openRxiv

    Prof. John W Holloway

58. 
    The role of epigenetics in multi‐generational transmission of asthma: An NIAID workshop report‐based narrative review

    Article • Clinical & Experimental Allergy, October 2022, Wiley

    Prof. John W Holloway

59. 
    Measurement of Exhaled Volatile Organic Compounds as a Biomarker for Personalised Medicine: Assessment of Short-Term Repeatability in Severe Asthma

    Article • Journal of Personalized Medicine, October 2022, MDPI AG

    Prof. John W Holloway

60. 
    Pre-pubertal smoke exposure of fathers and increased risk of offspring asthma: a possible transgenerational effect

    Article • European Respiratory Journal, September 2022, European Respiratory Society (ERS)

    Dr Gayan Bowatte, Prof. John W Holloway

61. 
    Paternal pre-pubertal tobacco smoking and offspring DNA methylation

    Article • September 2022, European Respiratory Society (ERS)

    Prof. John W Holloway

62. 
    Omics and Lung Function: A Need for Integration

    Article • American Review of Respiratory Disease, August 2022, American Thoracic Society

    Prof. John W Holloway

63. 
    British Society for Allergy and Immunology ( BSACI ) Abstracts of the World Allergy Organization ( WAO ) & BSACI 2022 UK...

    Article • Clinical & Experimental Allergy, July 2022, Wiley

    Prof. John W Holloway

64. 
    Association of childhood BMI trajectory with post-adolescent and adult lung function is mediated by pre-adolescent DNA methylation

    Article • July 2022, Springer Science + Business Media

    Prof. John W Holloway

65. 
    Association of upper airway bacterial microbiota and asthma: systematic review

    Article • Asia Pacific Allergy, July 2022, Wolters Kluwer Health

    Woo-Jung Song, Prof. John W Holloway

66. 
    Parental preconception BMI trajectories from childhood to adolescence and asthma in the future offspring

    Article • Journal of Allergy and Clinical Immunology, July 2022, Elsevier

    Prof. John W Holloway

67. 
    Temporal Whole-Transcriptomic Analysis of Characterized In Vitro and Ex Vivo Primary Nasal Epithelia

    Article • Frontiers in Cell and Developmental Biology, June 2022, Frontiers

    Prof. John W Holloway

68. 
    Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes

    Article • BMC Medical Genomics, June 2022, Springer Science + Business Media

    Prof. John W Holloway

69. 
    Ascaris exposure and its association with lung function, asthma, and DNA methylation in Northern Europe

    Article • Journal of Allergy and Clinical Immunology, June 2022, Elsevier

    Prof. John W Holloway

70. 
    Evaluating the Immune Response in Treatment-Naive Hospitalised Patients With Influenza and COVID-19

    Article • Frontiers in Immunology, May 2022, Frontiers

    Prof. John W Holloway

71. 
    Modeling Wheezing Spells Identifies Phenotypes with Different Outcomes and Genetic Associates

    Article • American Review of Respiratory Disease, April 2022, American Thoracic Society

    Professor Adnan Custovic, Prof. John W Holloway

72. 
    Validity and cardio-metabolic risk profiles of DNA methylation clocks among adults in south-central Côte d’Ivoire

    Article • Epigenetics Communications, April 2022, Springer Science + Business Media

    Prof. John W Holloway

73. 
    Nonlinear effects of environment on childhood asthma susceptibility

    Article • Pediatric Allergy and Immunology, April 2022, Wiley

    Professor Adnan Custovic, Prof. John W Holloway

74. 
    Article • Pediatric Allergy and Immunology, April 2022, Wiley

    Prof. John W Holloway

75. 
    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit

    Article • eLife, March 2022, eLife

    Prof. John W Holloway

76. 
    Article • Pediatric Allergy and Immunology, March 2022, Wiley

    Prof. John W Holloway

77. 
    Associations between child filaggrin mutations and maternal diet with the development of allergic diseases in children

    Article • Pediatric Allergy and Immunology, March 2022, Wiley

    Prof. John W Holloway

78. 
    Predicting Pulmonary Function From the Analysis of Voice: A Machine Learning Approach

    Article • Frontiers in Digital Health, February 2022, Frontiers

    Prof. John W Holloway

79. 
    Does DNA methylation mediate the association of age at puberty with FVC or FEV1?

    Article • ERJ Open Research, February 2022, European Respiratory Society (ERS)

    Prof. John W Holloway

80. 
    DNA Methylation and Asthma Acquisition during Adolescence and Post-Adolescence, an Epigenome-Wide Longitudinal Study

    Article • Journal of Personalized Medicine, February 2022, MDPI AG

    Prof. John W Holloway

81. 
    Newborn DNA methylation and asthma acquisition across adolescence and early adulthood

    Article • Clinical & Experimental Allergy, January 2022, Wiley

    Prof. John W Holloway

82. 
    Integration of Genomic Risk Scores to Improve the Prediction of Childhood Asthma Diagnosis

    Article • Journal of Personalized Medicine, January 2022, MDPI AG

    Professor Adnan Custovic, Prof. John W Holloway

83. 
    Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

    Article • Mutation Research/Reviews in Mutation Research, January 2022, Elsevier

    Prof. John W Holloway, Jari Lahti

84. 
    Association of prenatal acetaminophen use and acetaminophen metabolites with DNA methylation of newborns: analysis of two consecutive generations of the Isle of Wight birth cohort

    Article • Environmental Epigenetics, January 2022, Oxford University Press (OUP)

    Prof. John W Holloway

85. 
    Residential greenness-related DNA methylation changes

    Article • Environment International, January 2022, Elsevier

    Prof. John W Holloway

86. 
    Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation

    Article • European Respiratory Journal, November 2021, European Respiratory Society (ERS)

    Prof. John W Holloway

87. 
    Development of childhood asthma prediction models using machine learning approaches

    Article • Clinical and Translational Allergy, November 2021, Wiley

    Professor Adnan Custovic, Prof. John W Holloway

88. 
    Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study

    Article • ERJ Open Research, September 2021, European Respiratory Society (ERS)

    Erik Melén, Professor Adnan Custovic, Prof. John W Holloway

89. 
    Transcriptome analysis of ciliary differentiation in airway epithelium

    Article • September 2021, European Respiratory Society (ERS)

    Prof. John W Holloway

90. 
    Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

    Article • Nature Genetics, September 2021, Springer Science + Business Media

    Dr Christoph Bock, Jari Lahti, Prof. John W Holloway

91. 
    Exposures during the prepuberty period and future offspring’s health: evidence from human cohort studies†

    Article • Biology of Reproduction, August 2021, Oxford University Press (OUP)

    Prof. John W Holloway

92. 
    DNA Methylation and Asthma Acquisition During and Post-Adolescence, an Epigenome-Wide Longitudinal Study.

    Article • August 2021, Springer Science + Business Media

    Prof. John W Holloway

93. 
    BMI trajectory in childhood is associated with asthma incidence at young adulthood mediated by DNA methylation

    Article • Allergy Asthma & Clinical Immunology, July 2021, Springer Science + Business Media

    Prof. John W Holloway

94. 
    Childhood food allergy and food allergen sensitisation are associated with adult airways disease: A birth cohort study

    Article • Pediatric Allergy and Immunology, July 2021, Wiley

    Prof. John W Holloway

95. 
    Rapid microfluidic isolation of virally infected primary bronchial epithelial cells for single-cell RNA sequencing

    Article • BioTechniques, July 2021, Future Science

    Prof. John W Holloway

96. 
    Preconceptional smoking alters spermatozoal miRNAs of murine fathers and affects offspring’s body weight

    Article • International Journal of Obesity, May 2021, Springer Science + Business Media

    Prof. John W Holloway

97. 
    Distinct immune responses in patients infected with influenza or SARS-CoV-2, and in COVID-19 survivors, characterised by transcriptomic and cellular abundance differences in blood

    Article • May 2021, Cold Spring Harbor Laboratory Press

    Prof. John W Holloway

98. 
    Predicting pulmonary function from the analysis of voice: a machine learning approach

    Article • May 2021, openRxiv

    Prof. John W Holloway

99. 
    Causal Effects of Body Mass Index on Airflow Obstruction and Forced Mid-Expiratory Flow: A Mendelian Randomization Study Taking Interactions and Age-Specific Instruments Into Consideration Toward a Life Course Perspective

    Article • Frontiers in Public Health, May 2021, Frontiers

    Prof. John W Holloway

100. 
     Gaussian Bayesian network comparisons with graph ordering unknown

     Article • Computational Statistics & Data Analysis, May 2021, Elsevier

     Prof. John W Holloway

101. 
     Sex-specific longitudinal association of DNA methylation with lung function

     Article • ERJ Open Research, April 2021, European Respiratory Society (ERS)

     Prof. John W Holloway

102. 
     Development of Childhood Asthma Prediction Models using Machine Learning Approaches

     Article • April 2021, Cold Spring Harbor Laboratory Press

     Prof. John W Holloway, Professor Adnan Custovic

103. 
     Prenatal and prepubertal exposures to tobacco smoke in men may cause lower lung function in future offspring: a three-generation study using a causal modelling approach

     Article • European Respiratory Journal, April 2021, European Respiratory Society (ERS)

     Prof. John W Holloway

104. 
     Epigenome-scale comparison of DNA methylation between blood leukocytes and bronchial epithelial cells

     Article • Epigenomics, April 2021, Future Medicine

     Prof. John W Holloway

105. 
     Pre-adolescence DNA methylation is associated with BMI status change from pre- to post-adolescence

     Article • Clinical Epigenetics, March 2021, Springer Science + Business Media

     Prof. John W Holloway

106. 
     Placental uptake and metabolism of 25(OH)Vitamin D determines its activity within the fetoplacental unit

     Article • March 2021, openRxiv

     Prof. John W Holloway

107. 
     Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes

     Article • Disease Markers, February 2021, Hindawi Publishing Corporation

     Prof. John W Holloway

108. 
     Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood

     Article • Clinical Epigenetics, January 2021, Springer Science + Business Media

     Prof. John W Holloway

109. 
     DNA Methylation at Birth is Associated with Childhood Serum Immunoglobulin E Levels

     Article • Epigenetics Insights, January 2021, SAGE Publications

     Prof. John W Holloway

110. 
     Phenotypic and functional translation of IL33 genetics in asthma

     Article • Journal of Allergy and Clinical Immunology, January 2021, Elsevier

     Prof. John W Holloway

111. 
     Epigenome-Wide Association of Infant Feeding and Changes in DNA Methylation from Birth to 10 Years

     Article • Nutrients, December 2020, MDPI AG

     Prof. John W Holloway

112. 
     Nicotine and Its Downstream Metabolites in Maternal and Cord Sera: Biomarkers of Prenatal Smoking Exposure Associated with Offspring DNA Methylation

     Article • International Journal of Environmental Research and Public Health, December 2020, MDPI AG

     Prof. John W Holloway

113. 
     Maternal high fat diet in mice alters immune regulation and lung function in the offspring

     Article • British Journal Of Nutrition, November 2020, Cambridge University Press

     Prof. John W Holloway

114. 
     DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

     Article • Genome Medicine, November 2020, Springer Science + Business Media

     Prof. John W Holloway, Jari Lahti, Professor Trevor A Mori

115. 
     Sex‐specific associations of asthma acquisition with changes in DNA methylation during adolescence

     Article • Clinical & Experimental Allergy, November 2020, Wiley

     Prof. John W Holloway

116. 
     DNA methylation at birth is associated with lung function development until age 26 years

     Article • European Respiratory Journal, November 2020, European Respiratory Society (ERS)

     Wilfried Karmaus, Prof. John W Holloway

117. 
     Prediction of Lung Function in Adolescence Using Epigenetic Aging: A Machine Learning Approach

     Article • Methods and Protocols, November 2020, MDPI AG

     Prof. John W Holloway

118. 
     Reply to Owora et al.

     Article • Pediatric Allergy and Immunology, November 2020, Wiley

     Prof. John W Holloway

119. 
     Heritable hazards of smoking: Applying the “clean sheet” framework to further science and policy

     Article • Environmental and Molecular Mutagenesis, October 2020, Wiley

     Prof. John W Holloway

120. 
     Pubertal onset with adulthood lung function mediated by height growth in adolescence

     Article • ERJ Open Research, September 2020, European Respiratory Society (ERS)

     Prof. John W Holloway

121. 
     Prediction of Lung Function in Adolescence Using Epigenetic Aging: A Machine Learning Approach

     Article • September 2020, MDPI AG

     Prof. John W Holloway

122. 
     Genomic and phenomic insights from an atlas of genetic effects on DNA methylation

     Article • September 2020, Cold Spring Harbor Laboratory Press

     Jari Lahti, Prof. John W Holloway, Dr Christoph Bock

123. 
     Association of Maternal DNA Methylation and Offspring Birthweight

     Article • Reproductive Sciences, August 2020, Springer Science + Business Media

     Prof. John W Holloway

124. 
     Cohort Profile Update: The Isle of Wight Whole Population Birth Cohort (IOWBC)

     Article • International Journal of Epidemiology, July 2020, Oxford University Press (OUP)

     Prof. John W Holloway

125. 
     Assessing small airway function for early detection of lung function impairment

     Article • European Respiratory Journal, July 2020, European Respiratory Society (ERS)

     Prof. John W Holloway

126. 
     Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study

     Article • BMC Pulmonary Medicine, June 2020, Springer Science + Business Media

     Prof. John W Holloway, Andre FS Amaral

127. 
     Next Generation Exome Sequencing of paediatric Asthma Identifies Rare and Novel Variants in Candidate Genes

     Article • June 2020, Springer Science + Business Media

     Prof. John W Holloway

128. 
     Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study

     Article • Environmental Health Perspectives, June 2020, Environmental Health Perspectives

     Prof. John W Holloway

129. 
     Breastfeeding changes infants DNA

     Article • International Journal of Environmental Research and Public Health, May 2020, MDPI AG

     Prof. John W Holloway

130. 
     Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium

     Article • JCI Insight, April 2020, American Society for Clinical Investigation

     Prof. John W Holloway

131. 
     Changes of DNA methylation are associated with changes in lung function during adolescence

     Article • April 2020, Springer Science + Business Media

     Prof. John W Holloway

132. 
     Prediction Models for Childhood Asthma: A Systematic Review

     Article • Pediatric Allergy and Immunology, March 2020, Wiley

     Prof. John W Holloway

133. 
     Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

     Article • Genome Medicine, March 2020, Springer Science + Business Media

     Prof. John W Holloway, Jari Lahti

134. 
     Association of adult lung function with accelerated biological aging

     Article • Aging, January 2020, Impact Journals, LLC

     Prof. John W Holloway, Andre FS Amaral

135. 
     Cold-induced urticarial autoinflammatory syndrome related to factor XII activation

     Article • Nature Communications, January 2020, Springer Science + Business Media

     Prof. John W Holloway

136. 
     Different Measures of Diet Diversity During Infancy and the Association with Childhood Food Allergy in a UK Birth Cohort Study

     Article • The Journal of Allergy and Clinical Immunology In Practice, January 2020, Elsevier

     Prof. John W Holloway

137. 
     Age at onset of different pubertal signs in boys and girls and differential DNA methylation at age 10 and 18 years: an epigenome-wide follow-up study

     Article • Human Reproduction Open, January 2020, Oxford University Press (OUP)

     Prof. John W Holloway

138. 
     Interweaving Between Genetic and Epigenetic Studies on Childhood Asthma

     Article • Epigenetics Insights, January 2020, SAGE Publications

     Prof. John W Holloway

139. 
     Paternal DNA Methylation May Be Associated With Gestational Age at Birth

     Article • Epigenetics Insights, January 2020, SAGE Publications

     Prof. John W Holloway

140. 
     An evaluation of different classification algorithms for protein sequence-based reverse vaccinology prediction

     Article • PLOS One, December 2019, PLOS

     Prof. John W Holloway

141. 
     Association of asthma and smoking with lung function impairment in adolescence and early adulthood: the Isle of Wight Birth Cohort Study

     Article • European Respiratory Journal, December 2019, European Respiratory Society (ERS)

     Prof. John W Holloway

142. 
     Epigenome wide comparison of DNA methylation profile between paired umbilical cord blood and neonatal blood on Guthrie cards

     Article • Epigenetics, December 2019, Taylor & Francis

     Prof. John W Holloway

143. 
     Changes in DNA methylation from pre- to post-adolescence are associated with pubertal exposures

     Article • Clinical Epigenetics, December 2019, Springer Science + Business Media

     Prof. John W Holloway

144. 
     Estimation of Eosinophil Cells in Cord Blood with References Based on Blood in Adults via Bayesian Measurement Error Modeling

     Article • Bioinformatics, November 2019, Oxford University Press (OUP)

     Prof. John W Holloway

145. 
     Epigenome-wide association of father’s smoking with offspring DNA methylation: a hypothesis-generating study

     Article • Environmental Epigenetics, October 2019, Oxford University Press (OUP)

     Prof. John W Holloway

146. 
     GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI

     Article • Science Advances, September 2019, American Association for the Advancement of Science

     Dr Ulla Sovio, Prof. John W Holloway, Professor Alina Rodriguez

147. 
     Duration of breastfeeding is associated with leptin (LEP) DNA methylation profiles and BMI in 10-year-old children

     Article • Clinical Epigenetics, August 2019, Springer Science + Business Media

     Prof. John W Holloway

148. 
     Epigenome-wide association study of asthma and wheeze characterizes loci within HK1

     Article • Allergy Asthma & Clinical Immunology, July 2019, Springer Science + Business Media

     Prof. John W Holloway

149. 
     Distinguishing Wheezing Phenotypes from Infancy to Adolescence. A Pooled Analysis of Five Birth Cohorts

     Article • Annals of the American Thoracic Society, July 2019, American Thoracic Society

     Prof. John W Holloway, Professor Adnan Custovic

150. 
     DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

     Article • Clinical Epigenetics, July 2019, Springer Science + Business Media

     Prof. John W Holloway, Professor Alina Rodriguez

151. 
     Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns

     Article • Hypertension, June 2019, Wolters Kluwer Health

     Prof. John W Holloway, Jari Lahti

152. 
     Effect of gestational oily fish intake on the risk of allergy in children may be influenced by FADS1/2, ELOVL5 expression and DNA methylation

     Article • Genes & Nutrition, June 2019, Springer Science + Business Media

     Prof. John W Holloway

153. 
     Thioflavin T Monitoring of Guanine Quadruplex Formation in the rs689-Dependent INS Intron 1

     Article • Molecular Therapy — Nucleic Acids, June 2019, Elsevier

     Prof. John W Holloway

154. 
     Reply

     Article • Journal of Allergy and Clinical Immunology, June 2019, Elsevier

     Prof. John W Holloway

155. 
     Epigenome-wide association study of lung function level and its change

     Article • European Respiratory Journal, May 2019, European Respiratory Society (ERS)

     Prof. John W Holloway, Andre FS Amaral, Dr. Diana A van der Plaat

156. 
     Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

     Article • Nature Genetics, May 2019, Springer Science + Business Media

     Prof. John W Holloway, Jonas Bacelis, Gunn-Helen Moen

157. 
     Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

     Article • Nature Communications, April 2019, Springer Science + Business Media

     Prof. John W Holloway, Dr. Diana A van der Plaat, Jari Lahti

158. 
     The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects

     Article • European Journal of Epidemiology, March 2019, Springer Science + Business Media

     Prof. John W Holloway, Jari Lahti, Professor Adnan Custovic

159. 
     Different definitions of atopic dermatitis: Impact on prevalence estimates and associated risk factors

     Article • British Journal of Dermatology, March 2019, Wiley

     Prof. John W Holloway, Professor Adnan Custovic

160. 
     DNA methylation and allergic sensitizations, a genome-scale longitudinal study during adolescence

     Article • Allergy, February 2019, Wiley

     Prof. John W Holloway

161. 
     The Hertfordshire Cohort Study: an overview

     Article • F1000Research, January 2019, Faculty of 1000, Ltd.

     Sian Robinson, Prof. John W Holloway

162. 
     Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study

     Article • The Lancet Respiratory Medicine, January 2019, Elsevier

     Prof. John W Holloway

163. 
     Pubertal height growth and lung function in adolescence and early adulthood

     Article • American Review of Respiratory Disease, December 2018, American Thoracic Society

     Prof. John W Holloway, Osama Mahmoud, Professor Adnan Custovic

164. 
     Environmental Impact on Health across Generations: Policy Meets Biology. A Review of Animal and Human Models

     Article • Challenges, December 2018, MDPI AG

     Prof. John W Holloway

165. 
     Causes of variability in latent phenotypes of childhood wheeze

     Article • Journal of Allergy and Clinical Immunology, December 2018, Elsevier

     Prof. John W Holloway, Prof. Ultan F Power, Professor Adnan Custovic, Michael Shields

166. 
     Epigenome-wide Meta-analysis of DNA Methylation and Childhood Asthma

     Article • Journal of Allergy and Clinical Immunology, December 2018, Elsevier

     Prof. John W Holloway, Jari Lahti

167. 
     Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

     Article • October 2018, Cold Spring Harbor Laboratory Press

     Gunn-Helen Moen, Prof. John W Holloway

168. 
     Breastfeeding duration modifies the effect of smoking during pregnancy on eczema from early childhood to adolescence

     Article • Clinical & Experimental Allergy, October 2018, Wiley

     Prof. John W Holloway

169. 
     DNA methylation links prenatal smoking exposure to later life health outcomes in offspring

     Article • October 2018, Cold Spring Harbor Laboratory Press

     Professor Alina Rodriguez, Prof. John W Holloway

170. 
     Role of DNA Methylation in Type 2 Diabetes Etiology: Using Genotype as a Causal Anchor

     Article • Yearbook of Paediatric Endocrinology, September 2018, Bioscientifica

     Prof. John W Holloway

171. 
     Changes in miRNA Gene Expression during Wound Repair in Differentiated Normal Human Bronchial Epithelium

     Article • International Journal of Genomics, September 2018, Hindawi Publishing Corporation

     Prof. John W Holloway, Monika Dmitrzak-Węglarz, Claire Jackson

172. 
     SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts

     Article • Respiratory Research, August 2018, Springer Science + Business Media

     Prof. John W Holloway, Andre FS Amaral

173. 
     Maternal dietary antioxidant intake in pregnancy and childhood respiratory and atopic outcomes: birth cohort study

     Article • European Respiratory Journal, August 2018, European Respiratory Society (ERS)

     Prof. John W Holloway

174. 
     The Canmore Declaration: Statement of Principles for Planetary Health

     Article • Challenges, July 2018, MDPI AG

     Prof. John W Holloway

175. 
     Trans- and inter-generational epigenetic inheritance in allergic diseases

     Article • Journal of Allergy and Clinical Immunology, July 2018, Elsevier

     Prof. John W Holloway

176. 
     Cohort Profile: The Isle Of Wight Whole Population Birth Cohort (IOWBC)

     Article • International Journal of Epidemiology, March 2018, Oxford University Press (OUP)

     Prof. John W Holloway

177. 
     A three-generation study on the association of tobacco smoking with asthma

     Article • International Journal of Epidemiology, March 2018, Oxford University Press (OUP)

     Prof. John W Holloway

178. 
     Acquisition, remission, and persistence of eczema, asthma, and rhinitis in children

     Article • Clinical & Experimental Allergy, February 2018, Wiley

     Prof. John W Holloway, Wilfried Karmaus

179. 
     Changes in DNA Methylation from Age 18 to Pregnancy in Type 1, 2, and 17 T Helper and Regulatory T-Cells Pathway Genes

     Article • International Journal of Molecular Sciences, February 2018, MDPI AG

     Prof. John W Holloway

180. 
     Fixed Airways Obstruction In Smokers At 26 Years Of Age; An Early Indication Of COPD?

     Article • Journal of Allergy and Clinical Immunology, February 2018, Elsevier

     Prof. John W Holloway

181. 
     Lung Function Trajectories From Childhood To Young Adulthood; A Peek Into The Future Of Lung Health?

     Article • Journal of Allergy and Clinical Immunology, February 2018, Elsevier

     Prof. John W Holloway

182. 
     Asthma Does Not Explain A Decline In Post Bronchodilator Lung Function In Early Adult Life

     Article • Journal of Allergy and Clinical Immunology, February 2018, Elsevier

     Prof. John W Holloway

183. 
     Filaggrin mutations increase allergic airway disease in childhood and adolescence through interactions with eczema and aeroallergen sensitization

     Article • Clinical & Experimental Allergy, January 2018, Wiley

     Prof. John W Holloway, Wilfried Karmaus

184. 
     Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics

     Article • Human Molecular Genetics, January 2018, Oxford University Press (OUP)

     Prof. John W Holloway

185. 
     Subclonal Evolution of Cancer-Related Gene Mutations in p53 Immunopositive Patches in Human Skin

     Article • Journal of Investigative Dermatology, January 2018, Elsevier

     Prof. John W Holloway

186. 
     Zoonotic helminth exposure and risk of allergic diseases: A study of two generations in Norway

     Article • Clinical & Experimental Allergy, December 2017, Wiley

     Prof. John W Holloway

187. 
     Maternal and fetal genetic contribution to gestational weight gain

     Article • International Journal of Obesity, October 2017, Nature

     Prof. John W Holloway

188. 
     Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium

     Article • International Journal of Epidemiology, September 2017, Oxford University Press (OUP)

     Prof. John W Holloway, Jari Lahti

189. 
     Rhinitis Characterisation at 26 Years in the Isle of Wight Cohort

     Article • September 2017, European Respiratory Society (ERS)

     Prof. John W Holloway

190. 
     Atopic Sensitisation of the Isle of Wight Birth Cohort at 26 Years

     Article • September 2017, European Respiratory Society (ERS)

     Prof. John W Holloway

191. 
     Wheezing Characterisation of the Isle of Wight Birth Cohort at 26 Years

     Article • September 2017, European Respiratory Society (ERS)

     Prof. John W Holloway

192. 
     DNA methylation profiles between airway epithelium and proxy tissues in children

     Article • Acta Paediatrica, August 2017, Wiley

     Prof. John W Holloway

193. 
     MicroRNA-328 is involved in wound repair process in human bronchial epithelial cells

     Article • Respiratory Physiology & Neurobiology, August 2017, Elsevier

     Prof. John W Holloway

194. 
     Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium

     Article • Human Molecular Genetics, July 2017, Oxford University Press (OUP)

     Prof. John W Holloway

195. 
     Expression of the filaggrin gene in umbilical cord blood predicts eczema risk in infancy: A birth cohort study

     Article • Clinical & Experimental Allergy, June 2017, Wiley

     Prof. John W Holloway, Wilfried Karmaus

196. 
     Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity

     Article • June 2017, openRxiv

     Prof. John W Holloway

197. 
     Response to antenatal cholecalciferol supplementation is associated with common vitamin D related genetic variants

     Article • The Journal of Clinical Endocrinology & Metabolism, May 2017, Endocrine Society

     Prof. John W Holloway, Sian Robinson, Keith Godfrey

198. 
     Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the Pregnancy and Childhood Epigenetics (PACE) consortium

     Article • April 2017, openRxiv

     Prof. John W Holloway

199. 
     Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

     Article • BMC Pulmonary Medicine, March 2017, Springer Science + Business Media

     Andre FS Amaral, Prof. John W Holloway

200. 
     Maternal and fetal genetic contribution to gestational weight gain

     Article • March 2017, openRxiv

     Prof. John W Holloway

201. 
     Role of DNA Methylation in Type 2 Diabetes Etiology: Using Genotype as a Causal Anchor

     Article • Diabetes, February 2017, American Diabetes Association

     Prof. John W Holloway

202. 
     Multigenerational cohorts in patients with asthma and allergy

     Article • Journal of Allergy and Clinical Immunology, February 2017, Elsevier

     Prof. John W Holloway

203. 
     The Origins of Allergic Disease

     Article • January 2017, Elsevier

     Prof. John W Holloway

204. 
     Consistency and Variability of DNA Methylation in Women During Puberty, Young Adulthood, and Pregnancy

     Article • Genetics & Epigenetics, January 2017, SAGE Publications

     Prof. John W Holloway, Wilfried Karmaus

205. 
     Urinary prostanoids in preschool wheeze

     Article • European Respiratory Journal, December 2016, European Respiratory Society (ERS)

     Professor David Price, Prof. John W Holloway, Professor Marek Sanak

206. 
     TRPA1gene polymorphisms and childhood asthma

     Article • Pediatric Allergy and Immunology, December 2016, Wiley

     Prof. John W Holloway

207. 
     Tetanus vaccination is associated with differential DNA-methylation: Reduces the risk of asthma in adolescence

     Article • Vaccine, December 2016, Elsevier

     Prof. John W Holloway

208. 
     Comparison of miRNA profiling during airway epithelial repair in undifferentiated and differentiated cells in vitro

     Article • Journal of Applied Genetics, October 2016, Springer Science + Business Media

     Prof. John W Holloway

209. 
     Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients

     Article • Allergy, October 2016, Wiley

     Prof. John W Holloway

210. 
     Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma

     Article • PLOS One, October 2016, PLOS

     Prof. John W Holloway

211. 
     Is there an association between season of birth and blood DNA methylation in adulthood?

     Article • Allergy, September 2016, Wiley

     Prof. John W Holloway

212. 
     Variable selection in semi-parametric models

     Article • Statistical Methods in Medical Research, July 2016, SAGE Publications

     Prof. John W Holloway

213. 
     Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index

     Article • Molecular Psychiatry, May 2016, Springer Science + Business Media

     Prof Alexander P Maxwell, Prof. John W Holloway, Professor Alina Rodriguez, Fernando Fernandez-Aranda

214. 
     Adaptation to Life in the High Andes: Nocturnal Oxyhemoglobin Saturation in Early Development

     Article • SLEEP, May 2016, Oxford University Press (OUP)

     Prof. John W Holloway

215. 
     DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis

     Article • The American Journal of Human Genetics, April 2016, Elsevier

     Prof. John W Holloway

216. 
     Season of birth, epigenetics, and allergic disease

     Article • Allergy, March 2016, Wiley

     Prof. John W Holloway

217. 
     Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation inMOCS3,IFIT3andSERPINA12

     Article • Thorax, February 2016, BMJ

     Prof. John W Holloway

218. 
     Relation of FTO gene variants to fetal growth trajectories: Findings from the Southampton Women's survey

     Article • Placenta, February 2016, Elsevier

     Prof. John W Holloway, Professor Rohan M Lewis

219. 
     Interaction between theDNAH9gene and early smoke exposure in bronchial hyperresponsiveness

     Article • European Respiratory Journal, January 2016, European Respiratory Society (ERS)

     Prof. John W Holloway

220. 
     Evaluating the efficacy of breastfeeding guidelines on long-term outcomes for allergic disease

     Article • Allergy, January 2016, Wiley

     Prof. John W Holloway

221. 
     The Genetics of Allergic Disease and Asthma

     Article • January 2016, Elsevier

     Prof. John W Holloway

222. 
     Identifying heterogeneous transgenerational DNA methylation sites via clustering in beta regression

     Article • The Annals of Applied Statistics, December 2015, Institute of Mathematical Statistics

     Prof. John W Holloway

223. 
     Breeding and Reproductive Phenology of Eastern Diamond-Backed Rattlesnakes (Crotalus adamanteus) in South Carolina

     Article • Journal of Herpetology, December 2015, Society for the Study of Amphibians and Reptiles

     Prof. John W Holloway

224. 
     Parent-determined oral montelukast therapy for preschool wheeze with stratification for arachidonate 5-lipoxygenase (ALOX5) promoter genotype: a multicentre, randomised, placebo-controlled trial

     Article • Efficacy and Mechanism Evaluation, November 2015, National Institute for Health Research

     Prof. John W Holloway

225. 
     Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

     Article • Nature Genetics, October 2015, Nature

     Prof. John W Holloway, Jonas Bacelis, Professor Adnan Custovic

226. 
     DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection

     Article • Genome Medicine, August 2015, Springer Science + Business Media

     Prof. John W Holloway

227. 
     Does allergy beginin utero?

     Article • Pediatric Allergy and Immunology, July 2015, Wiley

     Prof. John W Holloway

228. 
     Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription

     Article • AJP Lung Cellular and Molecular Physiology, July 2015, American Physiological Society

     Prof. John W Holloway

229. 
     Identifying CpG sites associated with eczema via random forest screening of epigenome-scale DNA methylation

     Article • Clinical Epigenetics, July 2015, Springer Science + Business Media

     Prof. John W Holloway

230. 
     A statistical method for single sample analysis of HumanMethylation450 array data: genome-wide methylation analysis of patients with imprinting disorders

     Article • Clinical Epigenetics, April 2015, Springer Science + Business Media

     Prof. John W Holloway

231. 
     Exome Analysis of Patients with Concurrent Pediatric Inflammatory Bowel Disease and Autoimmune Disease

     Article • Inflammatory Bowel Diseases, April 2015, Wolters Kluwer Health

     Prof. John W Holloway

232. 
     Maternal selenium status in pregnancy, offspring glutathione peroxidase 4 genotype, and childhood asthma

     Article • Journal of Allergy and Clinical Immunology, April 2015, Elsevier

     Prof. John W Holloway

233. 
     Rapid detection of diagnostic targets using isothermal amplification and HyBeacon probes – A homogenous system for sequence-specific detection

     Article • Molecular and Cellular Probes, April 2015, Elsevier

     Prof. John W Holloway

234. 
     The Study Team for Early Life Asthma Research (STELAR) consortium ‘Asthma e-lab’: team science bringing data, methods and investigators together: Figure 1

     Article • Thorax, March 2015, BMJ

     Prof. John W Holloway, Professor Adnan Custovic

235. 
     Effects of phthalate exposure on asthma may be mediated through alterations in DNA methylation

     Article • Clinical Epigenetics, March 2015, Springer Science + Business Media

     Prof. John W Holloway

236. 
     Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents

     Article • Diabetes, February 2015, American Diabetes Association

     Dr Jessica C Kiefte-de Jong, Prof. John W Holloway

237. 
     Developmental determinants in non-communicable chronic diseases and ageing

     Article • Thorax, January 2015, BMJ

     Prof. John W Holloway, Dr Giacomo Cavalli

238. 
     A novel common variant in DCST2 is associated with length in early life and height in adulthood

     Article • Human Molecular Genetics, October 2014, Oxford University Press (OUP)

     Prof. John W Holloway, Professor Alina Rodriguez, Professor Adnan Custovic

239. 
     Intermittent montelukast in children aged 10 months to 5 years with wheeze (WAIT trial): a multicentre, randomised, placebo-controlled trial

     Article • The Lancet Respiratory Medicine, October 2014, Elsevier

     Prof. John W Holloway, Professor Marek Sanak

240. 
     Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence

     Article • Journal of Allergy and Clinical Immunology, October 2014, Elsevier

     Prof. John W Holloway

241. 
     Allergic sensitization and filaggrin variants predispose to the comorbidity of eczema, asthma, and rhinitis: results from the Isle of Wight birth cohort

     Article • Clinical & Experimental Allergy, August 2014, Wiley

     Prof. John W Holloway, Wilfried Karmaus

242. 
     FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals

     Article • Human Molecular Genetics, August 2014, Oxford University Press (OUP)

     Prof. John W Holloway

243. 
     Variants Close to NTRK2 Gene Are Associated With Birth Weight in Female Twins

     Article • Twin Research and Human Genetics, June 2014, Cambridge University Press

     Prof. John W Holloway

244. 
     Alpha‐tryptase gene variation is associated with levels of circulating I g E and lung function in asthma

     Article • Clinical & Experimental Allergy, May 2014, Wiley

     Prof. John W Holloway

245. 
     Asthma genetics and personalised medicine

     Article • The Lancet Respiratory Medicine, May 2014, Elsevier

     Prof. John W Holloway

246. 
     Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty

     Article • Human Molecular Genetics, April 2014, Oxford University Press (OUP)

     Prof. John W Holloway, Professor Alina Rodriguez

247. 
     Prenatal development is linked to bronchial reactivity: epidemiological and animal model evidence

     Article • Scientific Reports, April 2014, Nature

     Prof. John W Holloway

248. 
     Faculty of 1000 evaluation for DNA methylation and body-mass index: a genome-wide analysis.

     Article • March 2014, Faculty of 1000, Ltd.

     Prof. John W Holloway

249. 
     Infant lung function and wheeze in later childhood in the Southampton Women's Survey

     Article • European Respiratory Journal, February 2014, European Respiratory Society (ERS)

     Prof. John W Holloway

250. 
     Genome-wide DNA methylation analysis of patients with imprinting disorders identifies differentially methylated regions associated with novel candidate imprinted genes

     Article • Journal of Medical Genetics, February 2014, BMJ

     Prof. John W Holloway

251. 
     Association of Filaggrin Variants with Asthma and Rhinitis: Is Eczema or Allergic Sensitization Status an Effect Modifier?

     Article • International Archives of Allergy and Immunology, January 2014, Karger Publishers

     Prof. John W Holloway

252. 
     Oral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylation

     Article • Clinical Epigenetics, January 2014, Springer Science + Business Media

     Prof. John W Holloway

253. 
     Prenatal alcohol exposure and childhood atopic disease: A Mendelian randomization approach

     Article • Journal of Allergy and Clinical Immunology, January 2014, Elsevier

     Prof. John W Holloway

254. 
     The interplay of DNA methylation over time with Th2 pathway genetic variants on asthma risk and temporal asthma transition

     Article • Clinical Epigenetics, January 2014, Springer Science + Business Media

     Prof. John W Holloway

255. 
     Epigenomics and allergic disease

     Article • Epigenomics, December 2013, Future Medicine

     Prof. John W Holloway

256. 
     A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

     Article • Nature Genetics, November 2013, Nature

     Prof. John W Holloway, Professor Adnan Custovic

257. 
     EAACI position statement on asthma exacerbations and severe asthma

     Article • Allergy, November 2013, Wiley

     Prof. John W Holloway, Professor Adnan Custovic

258. 
     Altered microRNA expression profile during epithelial wound repair in bronchial epithelial cells

     Article • BMC Pulmonary Medicine, November 2013, Springer Science + Business Media

     Prof. John W Holloway

259. 
     Faculty of 1000 evaluation for Mutation in folate metabolism causes epigenetic instability and transgenerational effects on development.

     Article • October 2013, Faculty of 1000, Ltd.

     Prof. John W Holloway

260. 
     Dysregulation of Complement System and CD4+ T Cell Activation Pathways Implicated in Allergic Response

     Article • PLOS One, October 2013, PLOS

     Prof. John W Holloway

261. 
     Sensitization via Healthy Skin Programs Th2 Responses in Individuals with Atopic Dermatitis

     Article • Journal of Investigative Dermatology, October 2013, Elsevier

     Prof. John W Holloway

262. 
     Genome-wide association studies in asthma; perhaps, the end of the beginning

     Article • Current Opinion in Allergy and Clinical Immunology, October 2013, Wolters Kluwer Health

     Prof. John W Holloway

263. 
     Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children

     Article • BMC Medical Genetics, September 2013, Springer Science + Business Media

     Prof. John W Holloway

264. 
     Faculty of 1000 evaluation for RNA interference knockdown of DNA methyl-transferase 3 affects gene alternative splicing in the honey bee.

     Article • September 2013, Faculty of 1000, Ltd.

     Prof. John W Holloway

265. 
     Effect of GSTM2-5polymorphisms in relation to tobacco smoke exposures on lung function growth: a birth cohort study

     Article • BMC Pulmonary Medicine, September 2013, Springer Science + Business Media

     Prof. John W Holloway

266. 
     Faculty of 1000 evaluation for A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.

     Article • July 2013, Faculty of 1000, Ltd.

     Prof. John W Holloway

267. 
     MUC5AC and inflammatory mediators associated with respiratory outcomes in the British 1946 birth cohort

     Article • Respirology, July 2013, Wiley

     Prof. John W Holloway

268. 
     Interactive effect of STAT6 and IL13gene polymorphisms on eczema status: results from a longitudinal and a cross-sectional study

     Article • BMC Medical Genetics, July 2013, Springer Science + Business Media

     Prof. John W Holloway

269. 
     Faculty of 1000 evaluation for Adult monozygotic twins discordant for intra-uterine growth have indistinguishable genome-wide DNA methylation profiles.

     Article • June 2013, Faculty of 1000, Ltd.

     Prof. John W Holloway

270. 
     Faculty of 1000 evaluation for A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression.

     Article • April 2013, Faculty of 1000, Ltd.

     Prof. John W Holloway

271. 
     HHIP,HDAC4,NCR3andRARBpolymorphisms affect fetal, childhood and adult lung function: Table 1–

     Article • European Respiratory Journal, February 2013, European Respiratory Society (ERS)

     Prof. John W Holloway

272. 
     Faculty of 1000 evaluation for DNA Methylation in the Neuropeptide S Receptor 1 (NPSR1) Promoter in Relation to Asthma and Environmental Factors.

     Article • February 2013, Faculty of 1000, Ltd.

     Prof. John W Holloway

273. 
     Validation of novel wheeze phenotypes using longitudinal airway function and atopic sensitization data in the first 6 years of life: Evidence from the Southampton Women's survey

     Article • Pediatric Pulmonology, February 2013, Wiley

     Prof. John W Holloway

274. 
     Epigenetic mechanisms and models in the origins of asthma

     Article • Current Opinion in Allergy and Clinical Immunology, February 2013, Wolters Kluwer Health

     Prof. John W Holloway

275. 
     The association of the cytoplasmic domains of interleukin 4 receptor alpha and interleukin 13 receptor alpha 2 regulates interleukin 4 signaling

     Article • Molecular BioSystems, January 2013, Royal Society of Chemistry

     Prof. John W Holloway

276. 
     Interaction of prenatal maternal smoking, interleukin 13 genetic variants and DNA methylation influencing airflow and airway reactivity

     Article • Clinical Epigenetics, January 2013, Springer Science + Business Media

     Prof. John W Holloway

277. 
     The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years

     Article • Clinical Epigenetics, January 2013, Springer Science + Business Media

     Prof. John W Holloway

278. 
     New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

     Article • Nature Genetics, December 2012, Springer Science + Business Media

     Professor Dorret I Boomsma, Prof. John W Holloway, Dr Ulla Sovio

279. 
     Leukotriene B4 receptor locus gene characterisation and association studies in asthma

     Article • BMC Medical Genetics, November 2012, Springer Science + Business Media

     Prof. John W Holloway

280. 
     DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants

     Article • Journal of the European Academy of Dermatology and Venereology, September 2012, Wiley

     Prof. John W Holloway

281. 
     Evidence of association between interferon regulatory factor 5 gene polymorphisms and asthma

     Article • Gene, August 2012, Elsevier

     Prof. John W Holloway

282. 
     The effect of parental allergy on childhood allergic diseases depends on the sex of the child

     Article • Journal of Allergy and Clinical Immunology, August 2012, Elsevier

     Prof. John W Holloway

283. 
     Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease

     Article • Thorax, July 2012, BMJ

     Prof. John W Holloway

284. 
     Increased expression of the 5-lipoxygenase pathway and its cellular localization in Barrett’s adenocarcinoma

     Article • Histopathology, June 2012, Wiley

     Prof. John W Holloway

285. 
     Genome-wide association study to identify genetic determinants of severe asthma

     Article • Thorax, May 2012, BMJ

     Prof. John W Holloway

286. 
     Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes

     Article • Gut, April 2012, BMJ

     Prof. John W Holloway

287. 
     Genomics and the respiratory effects of air pollution exposure

     Article • Respirology, April 2012, Wiley

     Prof. John W Holloway

288. 
     Common variants at 6q22 and 17q21 are associated with intracranial volume

     Article • Nature Genetics, April 2012, Springer Science + Business Media

     Professor Dorret I Boomsma, Dr Stefan Ropele, Prof. John W Holloway, Professor Alina Rodriguez, Dr Ulla Sovio

289. 
     Common variants at 12q15 and 12q24 are associated with infant head circumference

     Article • Nature Genetics, April 2012, Springer Science + Business Media

     Professor Dorret I Boomsma, Dr Stefan Ropele, Prof. John W Holloway, Jari Lahti, Professor Alina Rodriguez, Dr Ulla Sovio

290. 
     A genome-wide association meta-analysis identifies new childhood obesity loci

     Article • Nature Genetics, April 2012, Springer Science + Business Media

     Professor Dorret I Boomsma, Prof. John W Holloway

291. 
     No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels

     Article • Diabetes, March 2012, American Diabetes Association

     Prof. John W Holloway

292. 
     Interplay of Filaggrin Loss-of-Function Variants, Allergic Sensitization, and Eczema in a Longitudinal Study Covering Infancy to 18 Years of Age

     Article • PLOS One, March 2012, PLOS

     Prof. John W Holloway

293. 
     Successful grant writing

     Article • Paediatric Respiratory Reviews, March 2012, Elsevier

     Prof. John W Holloway

294. 
     Invited Lecture: Activation of the Epithelial Mesenchymal Trophic Unit in the Pathogenesis of Asthma

     Article • International Archives of Allergy and Immunology, January 2012, Karger Publishers

     Prof. John W Holloway

295. 
     Interleukin-13, but Not Indomethacin, Increases Cysteinyl-Leukotriene Synthesis in Human Lung Macrophages

     Article • Journal of Allergy, January 2012, Hindawi Publishing Corporation

     Prof. John W Holloway

296. 
     The genetic basis of allergy and asthma

     Article • January 2012, Elsevier

     Prof. John W Holloway

297. 
     Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function

     Article • American Review of Respiratory Disease, October 2011, American Thoracic Society

     Prof. John W Holloway

298. 
     Identification of ATPAF1 as a novel candidate gene for asthma in children

     Article • Journal of Allergy and Clinical Immunology, October 2011, Elsevier

     Prof. John W Holloway

299. 
     Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function

     Article • Nature Genetics, September 2011, Springer Science + Business Media

     Dr Massimo Mangino, Prof. John W Holloway

300. 
     Neurophysiological evidence for cognitive and brain functional adaptation in adolescents living at high altitude

     Article • Clinical Neurophysiology, September 2011, Elsevier

     Prof. John W Holloway

301. 
     I have taken my umbrella, so of course it does not rain: Figure 1

     Article • Thorax, August 2011, BMJ

     Prof. John W Holloway

302. 
     Adjusting wheal size measures to correct atopy misclassification

     Article • International Journal of General Medicine, August 2011, Taylor & Francis

     Mr JIANJUN GAN, Prof. John W Holloway

303. 
     Relationship of vitamin D status to adult lung function and COPD

     Article • Thorax, June 2011, BMJ

     Prof. John W Holloway

304. 
     A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom

     Article • Journal of Allergy and Clinical Immunology, January 2011, Elsevier

     Prof. John W Holloway

305. 
     Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma

     Article • Journal of Allergy and Clinical Immunology, December 2010, Elsevier

     Prof. John W Holloway

306. 
     A Large-Scale, Consortium-Based Genomewide Association Study of Asthma

     Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, September 2010, New England Journal of Medicine (NEJM/MMS)

     Prof. Dr. med. Jon Genuneit, Prof. John W Holloway, Miriam Moffatt

307. 
     The relationship between infant lung function and the risk of wheeze in the preschool years

     Article • Pediatric Pulmonology, September 2010, Wiley

     Prof. John W Holloway

308. 
     The Role of Histamine Degradation Gene Polymorphisms in Moderating the Effects of Food Additives on Children's ADHD Symptoms

     Article • American Journal of Psychiatry, September 2010, American Psychiatric Association

     Prof. John W Holloway

309. 
     Maternal Nrf2 and gluthathione-S-transferase polymorphisms do not modify associations of prenatal tobacco smoke exposure with asthma and lung function in school-aged children

     Article • Thorax, August 2010, BMJ

     Prof. John W Holloway

310. 
     Using genetics to predict the natural history of asthma?

     Article • Journal of Allergy and Clinical Immunology, August 2010, Elsevier

     Prof. John W Holloway

311. 
     ADAM33 expression in atherosclerotic lesions and relationship of ADAM33 gene variation with atherosclerosis

     Article • Atherosclerosis, July 2010, Elsevier

     Prof. John W Holloway

312. 
     Development of aptitude at altitude

     Article • Developmental Science, May 2010, Wiley

     Prof. John W Holloway

313. 
     Genetic polymorphisms in the endotoxin receptor may influence platelet count as part of the acute phase response in critically ill children

     Article • Intensive Care Medicine, March 2010, Springer Science + Business Media

     Prof. John W Holloway

314. 
     Genetics of allergic disease

     Article • Journal of Allergy and Clinical Immunology, February 2010, Elsevier

     Prof. John W Holloway

315. 
     Alpha Tryptase: Potential Roles in Inflammation Distinct from those of β-tryptase

     Article • Journal of Allergy and Clinical Immunology, February 2010, Elsevier

     Dr Mogibelrahman Khedr, Prof. John W Holloway

316. 
     The Genetics of Allergic Disease and Asthma

     Article • January 2010, Elsevier

     Prof. John W Holloway

317. 
     Glutathione-S-transferase genes and asthma phenotypes: a Human Genome Epidemiology (HuGE) systematic review and meta-analysis including unpublished data

     Article • International Journal of Epidemiology, December 2009, Oxford University Press (OUP)

     Prof. John W Holloway

318. 
     Genome-wide association study identifies five loci associated with lung function

     Article • Nature Genetics, December 2009, Springer Science + Business Media

     Dr Massimo Mangino, Prof. John W Holloway

319. 
     Identification of PCDH1 as a Novel Susceptibility Gene for Bronchial Hyperresponsiveness

     Article • American Review of Respiratory Disease, November 2009, American Thoracic Society

     Prof. John W Holloway

320. 
     Atopy susceptibility and chromosome 19q13

     Article • Allergy, November 2009, Wiley

     Prof. John W Holloway

321. 
     Mortality in adult intensive care patients with severe systemic inflammatory response syndromes is strongly associated with the hypo-immune TNF −238A polymorphism

     Article • Immunogenetics, August 2009, Springer Science + Business Media

     Prof. John W Holloway

322. 
     Contribution of functional variation in theIL13gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort

     Article • Allergy, August 2009, Wiley

     Prof. John W Holloway

323. 
     Cytoplasmic tail of IL-13Rα2 regulates IL-4 signal transduction

     Article • Biochemical Society Transactions, August 2009, Portland Press Ltd.

     Prof. John W Holloway

324. 
     Genetic susceptibility to the respiratory effects of air pollution

     Article • Postgraduate Medical Journal, July 2009, BMJ

     Prof. John W Holloway

325. 
     Copy-Number Variation Genotyping of GSTT1 and GSTM1 Gene Deletions by Real-Time PCR

     Article • Clinical Chemistry, July 2009, AACC

     Prof. John W Holloway

326. 
     Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution

     Article • PLoS Genetics, June 2009, PLOS

     Dr Massimo Mangino, Prof. John W Holloway

327. 
     PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline

     Article • Journal of Allergy and Clinical Immunology, June 2009, Elsevier

     Prof. John W Holloway

328. 
     Human mid-gestation amniotic fluid contains interleukin-16 bioactivity

     Article • Immunology, April 2009, Wiley

     Prof. John W Holloway

329. 
     Copy Number Variation at Loci for α- and β-Tryptases: Associations with the Asthma Phenotype.

     Article • April 2009, American Thoracic Society

     Prof. John W Holloway

330. 
     Association Analysis of Brain-Derived Neurotrophic Factor Gene Polymorphisms in Asthmatic Families

     Article • International Archives of Allergy and Immunology, March 2009, Karger Publishers

     Prof. John W Holloway

331. 
     Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development

     Article • European Respiratory Journal, February 2009, European Respiratory Society (ERS)

     Prof. John W Holloway

332. 
     Effect of β2-Adrenergic Receptor Polymorphism in Asthma Control of Patients Receiving Combination Treatment

     Article • Yonsei Medical Journal, January 2009, Yonsei University College of Medicine (KAMJE)

     Prof. John W Holloway

333. 
     17q21 Variants and Asthma — Questions and Answers

     Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, November 2008, New England Journal of Medicine (NEJM/MMS)

     Prof. John W Holloway

334. 
     A single-nucleotide polymorphism in intelectin 1 is associated with increased asthma risk

     Article • Journal of Allergy and Clinical Immunology, November 2008, Elsevier

     Prof. John W Holloway

335. 
     The role ofLTA4HandALOX5APpolymorphism in asthma and allergy susceptibility

     Article • Allergy, August 2008, Wiley

     Prof. John W Holloway

336. 
     Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells

     Article • Journal of Allergy and Clinical Immunology, June 2008, Elsevier

     Prof. John W Holloway

337. 
     Interpatient variability in rates of asthma progression: Can genetics provide an answer?

     Article • Journal of Allergy and Clinical Immunology, March 2008, Elsevier

     Prof. John W Holloway

338. 
     Asthma: advancing gene?environment studies

     Article • Clinical & Experimental Allergy, September 2007, Wiley

     Prof. John W Holloway

339. 
     Effect of IL-13 receptor α2 levels on the biological activity of IL-13 variant R110Q

     Article • Journal of Allergy and Clinical Immunology, July 2007, Elsevier

     Prof. John W Holloway

340. 
     Genetic association studies of interleukin-13 receptor  1 subunit gene polymorphisms in asthma and atopy

     Article • European Respiratory Journal, March 2007, European Respiratory Society (ERS)

     Prof. John W Holloway

341. 
     Association between a TGFβ1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients

     Article • Respiratory Medicine, March 2007, Elsevier

     Prof. John W Holloway

342. 
     Gene–environmental interaction in asthma

     Article • Current Opinion in Allergy and Clinical Immunology, February 2007, Wolters Kluwer Health

     Prof. John W Holloway

343. 
     Identifying novel genes contributing to asthma pathogenesis

     Article • Current Opinion in Allergy and Clinical Immunology, February 2007, Wolters Kluwer Health

     Prof. John W Holloway

344. 
     Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms

     Article • European Respiratory Journal, January 2007, European Respiratory Society (ERS)

     Prof. John W Holloway

345. 
     Association of TNF-? genetic polymorphism with HLA DPB1*0301

     Article • Clinical & Experimental Allergy, October 2006, Wiley

     Prof. John W Holloway

346. 
     IL-13 receptor α 2: A regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts

     Article • Journal of Allergy and Clinical Immunology, October 2006, Elsevier

     Prof. John W Holloway

347. 
     A polymorphism of MS4A2 (-109T>C) encoding the beta-chain of the high-affinity immunoglobulin E receptor (FceR1beta) is associated with a susceptibility to aspirin-intolerant asthma

     Article • Clinical & Experimental Allergy, July 2006, Wiley

     Prof. John W Holloway

348. 
     MUC7 Haplotype Analysis: Results from a Longitudinal Birth Cohort Support Protective Effect of the MUC7*5 Allele on Respiratory Function

     Article • Annals of Human Genetics, July 2006, Wiley

     Prof. John W Holloway

349. 
     The Genetics of Asthma: ADAM33 as an Example of a Susceptibility Gene

     Article • Proceedings of the American Thoracic Society, July 2006, American Thoracic Society

     Prof. John W Holloway

350. 
     IL-4 Receptor   Is an Important Modulator of IL-4 and IL-13 Receptor Binding: Implications for the Development of Therapeutic Targets

     Article • The Journal of Immunology, June 2006, The American Association of Immunologists

     Prof. John W Holloway

351. 
     The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma

     Article • Clinical & Experimental Allergy, June 2006, Wiley

     Prof. John W Holloway

352. 
     Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities

     Article • Journal of Allergy and Clinical Immunology, March 2006, Elsevier

     Prof. John W Holloway

353. 
     ADAM33: a newly identified protease involved in airway remodelling

     Article • Pulmonary Pharmacology & Therapeutics, February 2006, Elsevier

     Prof. John W Holloway

354. 
     The role of Toll-like receptors and related receptors of the innate immune system in asthma

     Article • Current Opinion in Allergy and Clinical Immunology, February 2006, Wolters Kluwer Health

     Prof. John W Holloway

355. 
     Association of asthma with a functional promoter polymorphism in the IL16 gene

     Article • Journal of Allergy and Clinical Immunology, January 2006, Elsevier

     Prof. John W Holloway

356. 
     ADAM33: A Newly Identified Gene in the Pathogenesis of Asthma

     Article • Immunology and Allergy Clinics of North America, November 2005, Elsevier

     Prof. John W Holloway

357. 
     Tissue localization and frequency of antigen-specific effector CD4+ T cells determines the development of allergic airway inflammation

     Article • Immunology and Cell Biology, October 2005, Nature

     Prof. John W Holloway

358. 
     Polymorphisms in A Disintegrin and Metalloprotease 33 ( ADAM33 ) Predict Impaired Early-Life Lung Function

     Article • American Review of Respiratory Disease, July 2005, American Thoracic Society

     Prof. John W Holloway, Professor Adnan Custovic

359. 
     Polymorphism of tandem repeat in promoter of 5-lipoxygenase in ASA-intolerant asthma: a positive association with airway hyperresponsiveness

     Article • Allergy, June 2005, Wiley

     Prof. John W Holloway

360. 
     β-Catenin/T-cell factor-mediated transcription is modulated by cell density in human bronchial epithelial cells

     Article • The International Journal of Biochemistry & Cell Biology, June 2005, Elsevier

     Prof. John W Holloway

361. 
     Association of thromboxane A2 receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma

     Article • Clinical & Experimental Allergy, May 2005, Wiley

     Prof. John W Holloway

362. 
     β-Adrenergic receptor polymorphism and asthma: True or false?

     Article • Journal of Allergy and Clinical Immunology, May 2005, Elsevier

     Prof. John W Holloway

363. 
     Is big beautiful? The continuing story of ADAM33 and asthma

     Article • Thorax, April 2005, BMJ

     Prof. John W Holloway

364. 
     Association of Tumor Necrosis Factor-α Polymorphisms and Ozone-induced Change in Lung Function

     Article • American Review of Respiratory Disease, January 2005, American Thoracic Society

     Prof. John W Holloway

365. 
     Identification and Function of a Novel Candidate Gene for Asthma:ADAM 33

     Article • Allergology International, January 2005, Japanese Society of Allergology

     Prof. John W Holloway

366. 
     Identification and possible functions of ADAM33 as an asthma susceptibility gene

     Article • Clinical & Experimental Allergy Reviews, December 2004, Wiley

     Prof. John W Holloway

367. 
     Characterization of Ciliated Bronchial Epithelium 1, a Ciliated Cell–Associated Gene Induced During Mucociliary Differentiation

     Article • American Journal of Respiratory Cell and Molecular Biology, November 2004, American Thoracic Society

     Prof. John W Holloway

368. 
     World Allergy Organization Guidelines for Prevention of Allergy and Allergic Asthma

     Article • International Archives of Allergy and Immunology, September 2004, Karger Publishers

     Prof. John W Holloway, Professor Adnan Custovic

369. 
     The discovery and role of ADAM33, a new candidate gene for asthma

     Article • Expert Reviews in Molecular Medicine, August 2004, Cambridge University Press

     Prof. John W Holloway

370. 
     Polymorphism of the mast cell chymase gene (CMA1) promoter region: lack of association with asthma but association with serum total immunoglobulin E levels in adult atopic dermatitis

     Article • Clinical & Experimental Allergy, July 2004, Wiley

     Prof. John W Holloway

371. 
     The Splicing and Fate of ADAM33 Transcripts in Primary Human Airways Fibroblasts

     Article • American Journal of Respiratory Cell and Molecular Biology, July 2004, American Thoracic Society

     Prof. John W Holloway

372. 
     ADAM33 polymorphism: association with bronchial hyper-responsiveness in Korean asthmatics

     Article • Clinical & Experimental Allergy, June 2004, Wiley

     Prof. John W Holloway

373. 
     Epithelial-Mesenchymal Communication in the Pathogenesis of Chronic Asthma

     Article • Proceedings of the American Thoracic Society, April 2004, American Thoracic Society

     Prof. John W Holloway

374. 
     Erratum to“TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis” [ATH 170 (2003) 187–190]

     Article • Atherosclerosis, March 2004, Elsevier

     Prof. John W Holloway

375. 
     The role of ADAM33 in the pathogenesis of asthma

     Article • Springer Seminars in Immunopathology, February 2004, Springer Science + Business Media

     Prof. John W Holloway

376. 
     Toll-like receptor polymorphisms and allergic disease: interpreting the evidence from genetic studies

     Article • Clinical & Experimental Allergy, February 2004, Wiley

     Prof. John W Holloway

377. 
     Lack of association of HLA class I genes and TNF alpha-308 polymorphism in toluene diisocyanate-induced asthma

     Article • Allergy, January 2004, Wiley

     Prof. John W Holloway

378. 
     Toll-like receptor 4 polymorphism and severity of atopy in asthmatics

     Article • Genes & Immunity, January 2004, Nature

     Prof. John W Holloway

379. 
     World Allergy Organization Guidelines for Prevention of Allergy and Allergic Asthma

     Article • Allergy & Clinical Immunology International - Journal of the World Allergy Organization, January 2004, Hogrefe Publishing Group

     Prof. John W Holloway, Professor Adnan Custovic

380. 
     Genetics

     Article • January 2004, Karger Publishers

     Prof. John W Holloway

381. 
     TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis

     Article • Atherosclerosis, September 2003, Elsevier

     Prof. John W Holloway

382. 
     ADAM33: a novel therapeutic target for asthma

     Article • Expert Opinion on Therapeutic Targets, August 2003, Informa Healthcare

     Prof. John W Holloway

383. 
     Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population

     Article • Clinical & Experimental Allergy, August 2003, Wiley

     Prof. John W Holloway

384. 
     Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population

     Article • Clinical & Experimental Allergy, August 2003, Wiley

     Prof. John W Holloway

385. 
     ADAM 33: just another asthma gene or a breakthrough in understanding the origins of bronchial hyperresponsiveness?

     Article • Thorax, June 2003, BMJ

     Prof. John W Holloway

386. 
     Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome

     Article • Biochemical Society Transactions, June 2003, Portland Press Ltd.

     Prof. John W Holloway

387. 
     Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma

     Article • Thorax, May 2003, BMJ

     Prof. John W Holloway

388. 
     Assessment of White Blood Cell Phagocytosis as an Immunological Indicator of Methylmercury Exposure in Birds

     Article • Archives of Environmental Contamination and Toxicology, May 2003, Springer Science + Business Media

     Prof. John W Holloway

389. 
     Kinetic Analysis of the Interleukin-13 Receptor Complex

     Article • Journal of Biological Chemistry, September 2002, American Society for Biochemistry & Molecular Biology (ASBMB)

     Prof. John W Holloway

390. 
     Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

     Article • Nature, July 2002, Nature

     Prof. John W Holloway

391. 
     Cooperative Effects of Th2 Cytokines and Allergen on Normal and Asthmatic Bronchial Epithelial Cells

     Article • The Journal of Immunology, July 2002, The American Association of Immunologists

     Prof. John W Holloway

392. 
     Reduced soluble CD14 levels in amniotic fluid and breast milk are associated with the subsequent development of atopy, eczema, or both

     Article • Journal of Allergy and Clinical Immunology, May 2002, Elsevier

     Prof. John W Holloway

393. 
     Meta-analysis for linkage to asthma and atopy in the chromosome 5q31-33 candidate region

     Article • Human Molecular Genetics, April 2001, Oxford University Press (OUP)

     Prof. John W Holloway

394. 
     Linkage analysis of the 5q31–33 candidate region for asthma in 240 UK families

     Article • Genes & Immunity, February 2001, Nature

     Prof. John W Holloway

395. 
     A retrospective collaboration on chromosome 5 by the International Consortium on Asthma Genetics (COAG)

     Article • Clinical & Experimental Allergy, January 2001, Wiley

     Prof. John W Holloway

396. 
     Variant LTC4 synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast

     Article • Thorax, October 2000, BMJ

     Prof. John W Holloway

397. 
     A first trial of retrospective collaboration for positional cloning in complex inheritance: Assay of the cytokine region on chromosome 5 by the Consortium on Asthma Genetics (COAG)

     Article • Proceedings of the National Academy of Sciences, September 2000, Proceedings of the National Academy of Sciences

     Prof. John W Holloway

398. 
     Association of beta2-adrenergic receptor polymorphisms with severe asthma

     Article • Clinical & Experimental Allergy, August 2000, Wiley

     Prof. John W Holloway

399. 
     Comparison of three methods for single nucleotide polymorphism typing for DNA bank studies: Sequence-specific oligonucleotide probe hybridisation, TaqMan liquid phase hybridisation, and microplate array diagonal gel electrophoresis (MADGE)

     Article • Human Mutation, October 1999, Wiley

     Prof. John W Holloway

400. 
     Interleukin-12 and allergic tissue response

     Article • Clinical & Experimental Allergy, October 1999, Wiley

     Prof. John W Holloway

401. 
     The genetic basis of atopic asthma

     Article • Clinical & Experimental Allergy, August 1999, Wiley

     Prof. John W Holloway

402. 
     Infection of Mice withMycobacterium bovis–Bacillus Calmette-Guérin (BCG) Suppresses Allergen-induced Airway Eosinophilia

     Article • Journal of Experimental Medicine, February 1998, Rockefeller University Press

     Prof. John W Holloway

403. 
     Lack of evidence of a significant association between HLA-DR, DQ and DP genotypes and atopy in families with HDM allergy

     Article • Clinical & Experimental Allergy, October 1996, Wiley

     Prof. John W Holloway

404. 
     Innate immunity: Mast cells in the front line

     Article • Current Biology, August 1996, Elsevier

     Prof. John W Holloway

405. 
     Genetics of Asthma: What's New?

     Article • Wiley

     Prof. John W Holloway

406. 
     Genetics of Asthma and Bronchial Hyperresponsiveness

     Article • Springer Science + Business Media

     Prof. John W Holloway