All Stories

  1. Immune transcriptomic differences in paediatric patients with SARS-CoV-2 compared to other lower respiratory tract infections
  2. Lung function epigenetic markers across the lifespan
  3. Paternal prepubertal passive smoke exposure is related to impaired lung function trajectories from childhood to middle age in their offspring
  4. Genetic characterization of preschool wheeze phenotypes
  5. HiFi Long-Read RNA Sequencing Enhances Clinical Diagnostics in Rare Disorders
  6. Trends in DNA Methylation over Time Between Parous and Nulliparous Young Women
  7. Patterns of Respiratory Symptoms and Asthma Diagnosis in School‐Age Children: Three Birth Cohorts
  8. Gene–Environment Interaction Affects Risk of Atopic Eczema: Population and In Vitro Studies
  9. Exploring geographic differences in IgE response through network and manifold analyses
  10. Boys who are overweight as teenagers risk passing on harmful epigenetic traits to future children.
  11. Maternal asthma and newborn DNA methylation
  12. The mutation burden of narrowband ultraviolet B phototherapy (NB-UVB) in human skin; relevance to NB-UVB lifetime exposures and skin cancer surveillance
  13. Advancing Pediatric and Longitudinal DNA Methylation Studies with CellsPickMe, an Integrated Blood Cell Deconvolution Method
  14. Defining the Blood Cytokine Profile in Asthma to Understand Asthma Heterogeneity
  15. Trajectories of airflow limitation from childhood to early adulthood: an analysis of six population-based birth cohorts
  16. Gene-environment interaction analysis in atopic eczema: evidence from large population datasets and modelling in vitro
  17. DNA methylation at birth and IgE trajectories from birth to adolescence, different patterns between White and Asian
  18. Cesarean delivery and blood DNA methylation at birth and childhood: Meta-analysis in the Pregnancy and Childhood Epigenetics Consortium
  19. Uplift of genetic diagnosis of rare respiratory disease using airway epithelium transcriptome analysis
  20. Exploring the genetics of airflow limitation in lung function across the lifespan – a polygenic risk score study
  21. Intergenerational association of DNA methylation between parents and offspring
  22. Tailored antisense oligonucleotides designed to correct aberrant splicing reveal actionable groups of mutations for rare genetic disorders
  23. Association of psoriasis with allergic multimorbidity of asthma, rhinitis, and eczema among adolescents: a cross-sectional study
  24. Lung function trajectories from school age to adulthood and their relationship with markers of cardiovascular disease risk
  25. Lung-function trajectories: relevance and implementation in clinical practice
  26. A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation
  27. Obstructive and restrictive spirometry from school age to adulthood: three birth cohort studies
  28. Genetic and Epigenetic Associations with Pre–Chronic Obstructive Pulmonary Disease Lung Function Trajectories
  29. Identification of eczema clusters and their association with filaggrin and atopic comorbidities: analysis of five birth cohorts
  30. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
  31. Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude
  32. Boys who smoke in their early teens risk passing on harmful epigenetic traits to future children
  33. The association of DNA methylation at birth with adolescent asthma is mediated by atopy
  34. Polymorphisms in Glutathione S-Transferase (GST) Genes Modify the Effect of Exposure to Maternal Smoking Metabolites in Pregnancy and Offspring DNA Methylation
  35. Current state and prospects of artificial intelligence in allergy
  36. Defusing the legal and ethical minefield of epigenetic applications in the military, defense, and security context
  37. Genetic Associates of Childhood Wheezing Phenotypes Identified
  38. Gene Expression in Cord Blood and Tuberculosis in Early Childhood: A Nested Case-Control Study in a South African Birth Cohort
  39. Current state and prospects of artificial intelligence in allergy
  40. A meta-analysis of genome-wide association studies of childhood wheezing phenotypes identifiesANXA1as a susceptibility locus for persistent wheezing
  41. Preconception origins of asthma, allergies and lung function: The influence of previous generations on the respiratory health of our children
  42. Fathers’ preconception smoking and offspring DNA methylation: A two generation study
  43. Eczema among adolescents in Kuwait: Prevalence, severity, sleep disturbance, antihistamine use, and risk factors
  44. Evolution of Eczema, Wheeze, and Rhinitis from Infancy to Early Adulthood: Four Birth Cohort Studies
  45. European and multi-ancestry genome-wide association meta-analysis of atopic dermatitis highlights importance of systemic immune regulation
  46. The role of epigenetics in multi‐generational transmission of asthma: An NIAID workshop report‐based narrative review
  47. Measurement of Exhaled Volatile Organic Compounds as a Biomarker for Personalised Medicine: Assessment of Short-Term Repeatability in Severe Asthma
  48. Pre-pubertal smoke exposure of fathers and increased risk of offspring asthma: a possible transgenerational effect
  49. Paternal pre-pubertal tobacco smoking and offspring DNA methylation
  50. Omics and Lung Function: A Need for Integration
  51. British Society for Allergy and Immunology ( BSACI ) Abstracts of the World Allergy Organization ( WAO ) & BSACI 2022 UK...
  52. Association of childhood BMI trajectory with post-adolescent and adult lung function is mediated by pre-adolescent DNA methylation
  53. Association of upper airway bacterial microbiota and asthma: systematic review
  54. Parental preconception BMI trajectories from childhood to adolescence and asthma in the future offspring
  55. Temporal Whole-Transcriptomic Analysis of Characterized In Vitro and Ex Vivo Primary Nasal Epithelia
  56. Genetics of early-life head circumference and genetic correlations with neurological, psychiatric and cognitive outcomes
  57. Ascaris exposure and its association with lung function, asthma, and DNA methylation in Northern Europe
  58. Evaluating the Immune Response in Treatment-Naive Hospitalised Patients With Influenza and COVID-19
  59. Modeling Wheezing Spells Identifies Phenotypes with Different Outcomes and Genetic Associates
  60. Validity and cardio-metabolic risk profiles of DNA methylation clocks among adults in south-central Côte d’Ivoire
  61. Nonlinear effects of environment on childhood asthma susceptibility
  62. Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
  63. Associations between child filaggrin mutations and maternal diet with the development of allergic diseases in children
  64. Predicting Pulmonary Function From the Analysis of Voice: A Machine Learning Approach
  65. Does DNA methylation mediate the association of age at puberty with FVC or FEV1?
  66. DNA Methylation and Asthma Acquisition during Adolescence and Post-Adolescence, an Epigenome-Wide Longitudinal Study
  67. Newborn DNA methylation and asthma acquisition across adolescence and early adulthood
  68. Integration of Genomic Risk Scores to Improve the Prediction of Childhood Asthma Diagnosis
  69. Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation
  70. Association of prenatal acetaminophen use and acetaminophen metabolites with DNA methylation of newborns: analysis of two consecutive generations of the Isle of Wight birth cohort
  71. Residential greenness-related DNA methylation changes
  72. Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation
  73. Development of childhood asthma prediction models using machine learning approaches
  74. Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study
  75. Transcriptome analysis of ciliary differentiation in airway epithelium
  76. Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
  77. Exposures during the prepuberty period and future offspring’s health: evidence from human cohort studies†
  78. DNA Methylation and Asthma Acquisition During and Post-Adolescence, an Epigenome-Wide Longitudinal Study.
  79. BMI trajectory in childhood is associated with asthma incidence at young adulthood mediated by DNA methylation
  80. Childhood food allergy and food allergen sensitisation are associated with adult airways disease: A birth cohort study
  81. Rapid microfluidic isolation of virally infected primary bronchial epithelial cells for single-cell RNA sequencing
  82. Preconceptional smoking alters spermatozoal miRNAs of murine fathers and affects offspring’s body weight
  83. Distinct immune responses in patients infected with influenza or SARS-CoV-2, and in COVID-19 survivors, characterised by transcriptomic and cellular abundance differences in blood
  84. Predicting pulmonary function from the analysis of voice: a machine learning approach
  85. Causal Effects of Body Mass Index on Airflow Obstruction and Forced Mid-Expiratory Flow: A Mendelian Randomization Study Taking Interactions and Age-Specific Instruments Into Consideration Toward a Life Course Perspective
  86. Gaussian Bayesian network comparisons with graph ordering unknown
  87. Sex-specific longitudinal association of DNA methylation with lung function
  88. Development of Childhood Asthma Prediction Models using Machine Learning Approaches
  89. Prenatal and prepubertal exposures to tobacco smoke in men may cause lower lung function in future offspring: a three-generation study using a causal modelling approach
  90. Epigenome-scale comparison of DNA methylation between blood leukocytes and bronchial epithelial cells
  91. Pre-adolescence DNA methylation is associated with BMI status change from pre- to post-adolescence
  92. Placental uptake and metabolism of 25(OH)Vitamin D determines its activity within the fetoplacental unit
  93. Next Generation Exome Sequencing of Pediatric Asthma Identifies Rare and Novel Variants in Candidate Genes
  94. Pre-adolescence DNA methylation is associated with lung function trajectories from pre-adolescence to adulthood
  95. DNA Methylation at Birth is Associated with Childhood Serum Immunoglobulin E Levels
  96. Phenotypic and functional translation of IL33 genetics in asthma
  97. Epigenome-Wide Association of Infant Feeding and Changes in DNA Methylation from Birth to 10 Years
  98. Nicotine and Its Downstream Metabolites in Maternal and Cord Sera: Biomarkers of Prenatal Smoking Exposure Associated with Offspring DNA Methylation
  99. Maternal high fat diet in mice alters immune regulation and lung function in the offspring
  100. DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
  101. Sex‐specific associations of asthma acquisition with changes in DNA methylation during adolescence
  102. DNA methylation at birth is associated with lung function development until age 26 years
  103. Prediction of Lung Function in Adolescence Using Epigenetic Aging: A Machine Learning Approach
  104. Reply to Owora et al.
  105. Heritable hazards of smoking: Applying the “clean sheet” framework to further science and policy
  106. Pubertal onset with adulthood lung function mediated by height growth in adolescence
  107. Prediction of Lung Function in Adolescence Using Epigenetic Aging: A Machine Learning Approach
  108. Genomic and phenomic insights from an atlas of genetic effects on DNA methylation
  109. Association of Maternal DNA Methylation and Offspring Birthweight
  110. Cohort Profile Update: The Isle of Wight Whole Population Birth Cohort (IOWBC)
  111. Assessing small airway function for early detection of lung function impairment
  112. Role of DNA methylation in the association of lung function with body mass index: a two-step epigenetic Mendelian randomisation study
  113. Next Generation Exome Sequencing of paediatric Asthma Identifies Rare and Novel Variants in Candidate Genes
  114. Genome-Wide DNA Methylation in Peripheral Blood and Long-Term Exposure to Source-Specific Transportation Noise and Air Pollution: The SAPALDIA Study
  115. Breastfeeding changes infants DNA
  116. Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium
  117. Changes of DNA methylation are associated with changes in lung function during adolescence
  118. Prediction Models for Childhood Asthma: A Systematic Review
  119. Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
  120. Association of adult lung function with accelerated biological aging
  121. Cold-induced urticarial autoinflammatory syndrome related to factor XII activation
  122. Different Measures of Diet Diversity During Infancy and the Association with Childhood Food Allergy in a UK Birth Cohort Study
  123. Age at onset of different pubertal signs in boys and girls and differential DNA methylation at age 10 and 18 years: an epigenome-wide follow-up study
  124. Interweaving Between Genetic and Epigenetic Studies on Childhood Asthma
  125. Paternal DNA Methylation May Be Associated With Gestational Age at Birth
  126. An evaluation of different classification algorithms for protein sequence-based reverse vaccinology prediction
  127. Association of asthma and smoking with lung function impairment in adolescence and early adulthood: the Isle of Wight Birth Cohort Study
  128. Epigenome wide comparison of DNA methylation profile between paired umbilical cord blood and neonatal blood on Guthrie cards
  129. Changes in DNA methylation from pre- to post-adolescence are associated with pubertal exposures
  130. Estimation of Eosinophil Cells in Cord Blood with References Based on Blood in Adults via Bayesian Measurement Error Modeling
  131. Epigenome-wide association of father’s smoking with offspring DNA methylation: a hypothesis-generating study
  132. GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
  133. Duration of breastfeeding is associated with leptin (LEP) DNA methylation profiles and BMI in 10-year-old children
  134. Epigenome-wide association study of asthma and wheeze characterizes loci within HK1
  135. Distinguishing Wheezing Phenotypes from Infancy to Adolescence. A Pooled Analysis of Five Birth Cohorts
  136. DNA methylation links prenatal smoking exposure to later life health outcomes in offspring
  137. Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns
  138. Effect of gestational oily fish intake on the risk of allergy in children may be influenced by FADS1/2, ELOVL5 expression and DNA methylation
  139. Thioflavin T Monitoring of Guanine Quadruplex Formation in the rs689-Dependent INS Intron 1
  140. Reply
  141. Epigenome-wide association study of lung function level and its change
  142. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
  143. Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight
  144. The Early Growth Genetics (EGG) and EArly Genetics and Lifecourse Epidemiology (EAGLE) consortia: design, results and future prospects
  145. Different definitions of atopic dermatitis: Impact on prevalence estimates and associated risk factors
  146. DNA methylation and allergic sensitizations, a genome-scale longitudinal study during adolescence
  147. The Hertfordshire Cohort Study: an overview
  148. Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study
  149. Pubertal height growth and lung function in adolescence and early adulthood
  150. Environmental Impact on Health across Generations: Policy Meets Biology. A Review of Animal and Human Models
  151. Causes of variability in latent phenotypes of childhood wheeze
  152. Epigenome-wide Meta-analysis of DNA Methylation and Childhood Asthma
  153. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
  154. Breastfeeding duration modifies the effect of smoking during pregnancy on eczema from early childhood to adolescence
  155. DNA methylation links prenatal smoking exposure to later life health outcomes in offspring
  156. Role of DNA Methylation in Type 2 Diabetes Etiology: Using Genotype as a Causal Anchor
  157. Changes in miRNA Gene Expression during Wound Repair in Differentiated Normal Human Bronchial Epithelium
  158. SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts
  159. Maternal dietary antioxidant intake in pregnancy and childhood respiratory and atopic outcomes: birth cohort study
  160. The Canmore Declaration: Statement of Principles for Planetary Health
  161. Trans- and inter-generational epigenetic inheritance in allergic diseases
  162. Cohort Profile: The Isle Of Wight Whole Population Birth Cohort (IOWBC)
  163. A three-generation study on the association of tobacco smoking with asthma
  164. Acquisition, remission, and persistence of eczema, asthma, and rhinitis in children
  165. Changes in DNA Methylation from Age 18 to Pregnancy in Type 1, 2, and 17 T Helper and Regulatory T-Cells Pathway Genes
  166. Fixed Airways Obstruction In Smokers At 26 Years Of Age; An Early Indication Of COPD?
  167. Lung Function Trajectories From Childhood To Young Adulthood; A Peek Into The Future Of Lung Health?
  168. Asthma Does Not Explain A Decline In Post Bronchodilator Lung Function In Early Adult Life
  169. Filaggrin mutations increase allergic airway disease in childhood and adolescence through interactions with eczema and aeroallergen sensitization
  170. Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics
  171. Subclonal Evolution of Cancer-Related Gene Mutations in p53 Immunopositive Patches in Human Skin
  172. Zoonotic helminth exposure and risk of allergic diseases: A study of two generations in Norway
  173. Maternal and fetal genetic contribution to gestational weight gain
  174. Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium
  175. Rhinitis Characterisation at 26 Years in the Isle of Wight Cohort
  176. Atopic Sensitisation of the Isle of Wight Birth Cohort at 26 Years
  177. Wheezing Characterisation of the Isle of Wight Birth Cohort at 26 Years
  178. DNA methylation profiles between airway epithelium and proxy tissues in children
  179. MicroRNA-328 is involved in wound repair process in human bronchial epithelial cells
  180. Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium
  181. Expression of the filaggrin gene in umbilical cord blood predicts eczema risk in infancy: A birth cohort study
  182. Genetic architecture of early childhood growth phenotypes gives insights into their link with later obesity
  183. Response to antenatal cholecalciferol supplementation is associated with common vitamin D related genetic variants
  184. Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: Findings from the Pregnancy and Childhood Epigenetics (PACE) consortium
  185. Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies
  186. Maternal and fetal genetic contribution to gestational weight gain
  187. Role of DNA Methylation in Type 2 Diabetes Etiology: Using Genotype as a Causal Anchor
  188. Multigenerational cohorts in patients with asthma and allergy
  189. The Origins of Allergic Disease
  190. Consistency and Variability of DNA Methylation in Women During Puberty, Young Adulthood, and Pregnancy
  191. Urinary prostanoids in preschool wheeze
  192. TRPA1gene polymorphisms and childhood asthma
  193. Tetanus vaccination is associated with differential DNA-methylation: Reduces the risk of asthma in adolescence
  194. Comparison of miRNA profiling during airway epithelial repair in undifferentiated and differentiated cells in vitro
  195. Airway and peripheral urokinase plasminogen activator receptor is elevated in asthma, and identifies a severe, nonatopic subset of patients
  196. Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma
  197. Is there an association between season of birth and blood DNA methylation in adulthood?
  198. Variable selection in semi-parametric models
  199. Evidence for three genetic loci involved in both anorexia nervosa risk and variation of body mass index
  200. Adaptation to Life in the High Andes: Nocturnal Oxyhemoglobin Saturation in Early Development
  201. DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
  202. Season of birth, epigenetics, and allergic disease
  203. Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation inMOCS3,IFIT3andSERPINA12
  204. Relation of FTO gene variants to fetal growth trajectories: Findings from the Southampton Women's survey
  205. Interaction between theDNAH9gene and early smoke exposure in bronchial hyperresponsiveness
  206. Evaluating the efficacy of breastfeeding guidelines on long-term outcomes for allergic disease
  207. The Genetics of Allergic Disease and Asthma
  208. Identifying heterogeneous transgenerational DNA methylation sites via clustering in beta regression
  209. Breeding and Reproductive Phenology of Eastern Diamond-Backed Rattlesnakes (Crotalus adamanteus) in South Carolina
  210. Parent-determined oral montelukast therapy for preschool wheeze with stratification for arachidonate 5-lipoxygenase (ALOX5) promoter genotype: a multicentre, randomised, placebo-controlled trial
  211. Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis
  212. DNA methylation loci associated with atopy and high serum IgE: a genome-wide application of recursive Random Forest feature selection
  213. Does allergy beginin utero?
  214. Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription
  215. Identifying CpG sites associated with eczema via random forest screening of epigenome-scale DNA methylation
  216. A statistical method for single sample analysis of HumanMethylation450 array data: genome-wide methylation analysis of patients with imprinting disorders
  217. Exome Analysis of Patients with Concurrent Pediatric Inflammatory Bowel Disease and Autoimmune Disease
  218. Maternal selenium status in pregnancy, offspring glutathione peroxidase 4 genotype, and childhood asthma
  219. Rapid detection of diagnostic targets using isothermal amplification and HyBeacon probes – A homogenous system for sequence-specific detection
  220. The Study Team for Early Life Asthma Research (STELAR) consortium ‘Asthma e-lab’: team science bringing data, methods and investigators together: Figure 1
  221. Effects of phthalate exposure on asthma may be mediated through alterations in DNA methylation
  222. Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents
  223. Developmental determinants in non-communicable chronic diseases and ageing
  224. A novel common variant in DCST2 is associated with length in early life and height in adulthood
  225. Intermittent montelukast in children aged 10 months to 5 years with wheeze (WAIT trial): a multicentre, randomised, placebo-controlled trial
  226. Filaggrin loss-of-function mutations are associated with food allergy in childhood and adolescence
  227. Allergic sensitization and filaggrin variants predispose to the comorbidity of eczema, asthma, and rhinitis: results from the Isle of Wight birth cohort
  228. FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals
  229. Variants Close to NTRK2 Gene Are Associated With Birth Weight in Female Twins
  230. Alpha‐tryptase gene variation is associated with levels of circulating I g E and lung function in asthma
  231. Asthma genetics and personalised medicine
  232. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty
  233. Prenatal development is linked to bronchial reactivity: epidemiological and animal model evidence
  234. Faculty of 1000 evaluation for DNA methylation and body-mass index: a genome-wide analysis.
  235. Infant lung function and wheeze in later childhood in the Southampton Women's Survey
  236. Genome-wide DNA methylation analysis of patients with imprinting disorders identifies differentially methylated regions associated with novel candidate imprinted genes
  237. Association of Filaggrin Variants with Asthma and Rhinitis: Is Eczema or Allergic Sensitization Status an Effect Modifier?
  238. Oral contraceptives modify the effect of GATA3 polymorphisms on the risk of asthma at the age of 18 years via DNA methylation
  239. Prenatal alcohol exposure and childhood atopic disease: A Mendelian randomization approach
  240. The interplay of DNA methylation over time with Th2 pathway genetic variants on asthma risk and temporal asthma transition
  241. Epigenomics and allergic disease
  242. A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations
  243. EAACI position statement on asthma exacerbations and severe asthma
  244. Altered microRNA expression profile during epithelial wound repair in bronchial epithelial cells
  245. Faculty of 1000 evaluation for Mutation in folate metabolism causes epigenetic instability and transgenerational effects on development.
  246. Dysregulation of Complement System and CD4+ T Cell Activation Pathways Implicated in Allergic Response
  247. Sensitization via Healthy Skin Programs Th2 Responses in Individuals with Atopic Dermatitis
  248. Genome-wide association studies in asthma; perhaps, the end of the beginning
  249. Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children
  250. Faculty of 1000 evaluation for RNA interference knockdown of DNA methyl-transferase 3 affects gene alternative splicing in the honey bee.
  251. Effect of GSTM2-5polymorphisms in relation to tobacco smoke exposures on lung function growth: a birth cohort study
  252. Faculty of 1000 evaluation for A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.
  253. MUC5AC and inflammatory mediators associated with respiratory outcomes in the British 1946 birth cohort
  254. Interactive effect of STAT6 and IL13gene polymorphisms on eczema status: results from a longitudinal and a cross-sectional study
  255. Faculty of 1000 evaluation for Adult monozygotic twins discordant for intra-uterine growth have indistinguishable genome-wide DNA methylation profiles.
  256. Faculty of 1000 evaluation for A cell epigenotype specific model for the correction of brain cellular heterogeneity bias and its application to age, brain region and major depression.
  257. HHIP,HDAC4,NCR3andRARBpolymorphisms affect fetal, childhood and adult lung function: Table 1–
  258. Faculty of 1000 evaluation for DNA Methylation in the Neuropeptide S Receptor 1 (NPSR1) Promoter in Relation to Asthma and Environmental Factors.
  259. Validation of novel wheeze phenotypes using longitudinal airway function and atopic sensitization data in the first 6 years of life: Evidence from the Southampton Women's survey
  260. Epigenetic mechanisms and models in the origins of asthma
  261. The association of the cytoplasmic domains of interleukin 4 receptor alpha and interleukin 13 receptor alpha 2 regulates interleukin 4 signaling
  262. Interaction of prenatal maternal smoking, interleukin 13 genetic variants and DNA methylation influencing airflow and airway reactivity
  263. The interaction of genetic variants and DNA methylation of the interleukin-4 receptor gene increase the risk of asthma at age 18 years
  264. New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
  265. Leukotriene B4 receptor locus gene characterisation and association studies in asthma
  266. DNA methylation of the filaggrin gene adds to the risk of eczema associated with loss-of-function variants
  267. Evidence of association between interferon regulatory factor 5 gene polymorphisms and asthma
  268. The effect of parental allergy on childhood allergic diseases depends on the sex of the child
  269. Of flies, mice and men: a systematic approach to understanding the early life origins of chronic lung disease
  270. Increased expression of the 5-lipoxygenase pathway and its cellular localization in Barrett’s adenocarcinoma
  271. Genome-wide association study to identify genetic determinants of severe asthma
  272. Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes
  273. Genomics and the respiratory effects of air pollution exposure
  274. Common variants at 6q22 and 17q21 are associated with intracranial volume
  275. Common variants at 12q15 and 12q24 are associated with infant head circumference
  276. A genome-wide association meta-analysis identifies new childhood obesity loci
  277. No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
  278. Interplay of Filaggrin Loss-of-Function Variants, Allergic Sensitization, and Eczema in a Longitudinal Study Covering Infancy to 18 Years of Age
  279. Successful grant writing
  280. Invited Lecture: Activation of the Epithelial Mesenchymal Trophic Unit in the Pathogenesis of Asthma
  281. Interleukin-13, but Not Indomethacin, Increases Cysteinyl-Leukotriene Synthesis in Human Lung Macrophages
  282. The genetic basis of allergy and asthma
  283. Effect of Five Genetic Variants Associated with Lung Function on the Risk of Chronic Obstructive Lung Disease, and Their Joint Effects on Lung Function
  284. Identification of ATPAF1 as a novel candidate gene for asthma in children
  285. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
  286. Neurophysiological evidence for cognitive and brain functional adaptation in adolescents living at high altitude
  287. I have taken my umbrella, so of course it does not rain: Figure 1
  288. Adjusting wheal size measures to correct atopy misclassification
  289. Relationship of vitamin D status to adult lung function and COPD
  290. A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom
  291. Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood asthma
  292. A Large-Scale, Consortium-Based Genomewide Association Study of Asthma
  293. The relationship between infant lung function and the risk of wheeze in the preschool years
  294. The Role of Histamine Degradation Gene Polymorphisms in Moderating the Effects of Food Additives on Children's ADHD Symptoms
  295. Maternal Nrf2 and gluthathione-S-transferase polymorphisms do not modify associations of prenatal tobacco smoke exposure with asthma and lung function in school-aged children
  296. Using genetics to predict the natural history of asthma?
  297. ADAM33 expression in atherosclerotic lesions and relationship of ADAM33 gene variation with atherosclerosis
  298. Development of aptitude at altitude
  299. Genetic polymorphisms in the endotoxin receptor may influence platelet count as part of the acute phase response in critically ill children
  300. Genetics of allergic disease
  301. Alpha Tryptase: Potential Roles in Inflammation Distinct from those of β-tryptase
  302. The Genetics of Allergic Disease and Asthma
  303. Glutathione-S-transferase genes and asthma phenotypes: a Human Genome Epidemiology (HuGE) systematic review and meta-analysis including unpublished data
  304. Genome-wide association study identifies five loci associated with lung function
  305. Identification of PCDH1 as a Novel Susceptibility Gene for Bronchial Hyperresponsiveness
  306. Atopy susceptibility and chromosome 19q13
  307. Mortality in adult intensive care patients with severe systemic inflammatory response syndromes is strongly associated with the hypo-immune TNF −238A polymorphism
  308. Contribution of functional variation in theIL13gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort
  309. Cytoplasmic tail of IL-13Rα2 regulates IL-4 signal transduction
  310. Genetic susceptibility to the respiratory effects of air pollution
  311. Copy-Number Variation Genotyping of GSTT1 and GSTM1 Gene Deletions by Real-Time PCR
  312. Genome-Wide Association Scan Meta-Analysis Identifies Three Loci Influencing Adiposity and Fat Distribution
  313. PLAUR polymorphisms are associated with asthma, PLAUR levels, and lung function decline
  314. Human mid-gestation amniotic fluid contains interleukin-16 bioactivity
  315. Copy Number Variation at Loci for α- and β-Tryptases: Associations with the Asthma Phenotype.
  316. Association Analysis of Brain-Derived Neurotrophic Factor Gene Polymorphisms in Asthmatic Families
  317. Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development
  318. Effect of β2-Adrenergic Receptor Polymorphism in Asthma Control of Patients Receiving Combination Treatment
  319. 17q21 Variants and Asthma — Questions and Answers
  320. A single-nucleotide polymorphism in intelectin 1 is associated with increased asthma risk
  321. The role ofLTA4HandALOX5APpolymorphism in asthma and allergy susceptibility
  322. Epigenetic mechanisms silence a disintegrin and metalloprotease 33 expression in bronchial epithelial cells
  323. Interpatient variability in rates of asthma progression: Can genetics provide an answer?
  324. Asthma: advancing gene?environment studies
  325. Effect of IL-13 receptor α2 levels on the biological activity of IL-13 variant R110Q
  326. Genetic association studies of interleukin-13 receptor  1 subunit gene polymorphisms in asthma and atopy
  327. Association between a TGFβ1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients
  328. Gene–environmental interaction in asthma
  329. Identifying novel genes contributing to asthma pathogenesis
  330. Local genetic and environmental factors in asthma disease pathogenesis: chronicity and persistence mechanisms
  331. Association of TNF-? genetic polymorphism with HLA DPB1*0301
  332. IL-13 receptor α 2: A regulator of IL-13 and IL-4 signal transduction in primary human fibroblasts
  333. A polymorphism of MS4A2 (-109T>C) encoding the beta-chain of the high-affinity immunoglobulin E receptor (FceR1beta) is associated with a susceptibility to aspirin-intolerant asthma
  334. MUC7 Haplotype Analysis: Results from a Longitudinal Birth Cohort Support Protective Effect of the MUC7*5 Allele on Respiratory Function
  335. The Genetics of Asthma: ADAM33 as an Example of a Susceptibility Gene
  336. IL-4 Receptor   Is an Important Modulator of IL-4 and IL-13 Receptor Binding: Implications for the Development of Therapeutic Targets
  337. The cysteinyl-leukotriene type 1 receptor polymorphism 927T/C is associated with atopy severity but not with asthma
  338. Understanding the pathophysiology of severe asthma to generate new therapeutic opportunities
  339. ADAM33: a newly identified protease involved in airway remodelling
  340. The role of Toll-like receptors and related receptors of the innate immune system in asthma
  341. Association of asthma with a functional promoter polymorphism in the IL16 gene
  342. ADAM33: A Newly Identified Gene in the Pathogenesis of Asthma
  343. Tissue localization and frequency of antigen-specific effector CD4+ T cells determines the development of allergic airway inflammation
  344. Polymorphisms in A Disintegrin and Metalloprotease 33 ( ADAM33 ) Predict Impaired Early-Life Lung Function
  345. Polymorphism of tandem repeat in promoter of 5-lipoxygenase in ASA-intolerant asthma: a positive association with airway hyperresponsiveness
  346. β-Catenin/T-cell factor-mediated transcription is modulated by cell density in human bronchial epithelial cells
  347. Association of thromboxane A2 receptor gene polymorphism with the phenotype of acetyl salicylic acid-intolerant asthma
  348. β-Adrenergic receptor polymorphism and asthma: True or false?
  349. Is big beautiful? The continuing story of ADAM33 and asthma
  350. Association of Tumor Necrosis Factor-α Polymorphisms and Ozone-induced Change in Lung Function
  351. Identification and Function of a Novel Candidate Gene for Asthma:ADAM 33
  352. Identification and possible functions of ADAM33 as an asthma susceptibility gene
  353. Characterization of Ciliated Bronchial Epithelium 1, a Ciliated Cell–Associated Gene Induced During Mucociliary Differentiation
  354. World Allergy Organization Guidelines for Prevention of Allergy and Allergic Asthma
  355. The discovery and role of ADAM33, a new candidate gene for asthma
  356. Polymorphism of the mast cell chymase gene (CMA1) promoter region: lack of association with asthma but association with serum total immunoglobulin E levels in adult atopic dermatitis
  357. The Splicing and Fate of ADAM33 Transcripts in Primary Human Airways Fibroblasts
  358. ADAM33 polymorphism: association with bronchial hyper-responsiveness in Korean asthmatics
  359. Epithelial-Mesenchymal Communication in the Pathogenesis of Chronic Asthma
  360. Erratum to“TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis” [ATH 170 (2003) 187–190]
  361. The role of ADAM33 in the pathogenesis of asthma
  362. Toll-like receptor polymorphisms and allergic disease: interpreting the evidence from genetic studies
  363. Lack of association of HLA class I genes and TNF alpha-308 polymorphism in toluene diisocyanate-induced asthma
  364. Toll-like receptor 4 polymorphism and severity of atopy in asthmatics
  365. World Allergy Organization Guidelines for Prevention of Allergy and Allergic Asthma
  366. Genetics
  367. TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis
  368. ADAM33: a novel therapeutic target for asthma
  369. Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population
  370. Promoter polymorphism in the 5-lipoxygenase (ALOX5) and 5-lipoxygenase-activating protein (ALOX5AP) genes and asthma susceptibility in a Caucasian population
  371. ADAM 33: just another asthma gene or a breakthrough in understanding the origins of bronchial hyperresponsiveness?
  372. Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome
  373. Allelic association and functional studies of promoter polymorphism in the leukotriene C4 synthase gene (LTC4S) in asthma
  374. Assessment of White Blood Cell Phagocytosis as an Immunological Indicator of Methylmercury Exposure in Birds
  375. Kinetic Analysis of the Interleukin-13 Receptor Complex
  376. Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
  377. Cooperative Effects of Th2 Cytokines and Allergen on Normal and Asthmatic Bronchial Epithelial Cells
  378. Reduced soluble CD14 levels in amniotic fluid and breast milk are associated with the subsequent development of atopy, eczema, or both
  379. Meta-analysis for linkage to asthma and atopy in the chromosome 5q31-33 candidate region
  380. Linkage analysis of the 5q31–33 candidate region for asthma in 240 UK families
  381. A retrospective collaboration on chromosome 5 by the International Consortium on Asthma Genetics (COAG)
  382. Variant LTC4 synthase allele modifies cysteinyl leukotriene synthesis in eosinophils and predicts clinical response to zafirlukast
  383. A first trial of retrospective collaboration for positional cloning in complex inheritance: Assay of the cytokine region on chromosome 5 by the Consortium on Asthma Genetics (COAG)
  384. Association of beta2-adrenergic receptor polymorphisms with severe asthma
  385. Comparison of three methods for single nucleotide polymorphism typing for DNA bank studies: Sequence-specific oligonucleotide probe hybridisation, TaqMan liquid phase hybridisation, and microplate array diagonal gel electrophoresis (MADGE)
  386. Interleukin-12 and allergic tissue response
  387. The genetic basis of atopic asthma
  388. Infection of Mice withMycobacterium bovis–Bacillus Calmette-Guérin (BCG) Suppresses Allergen-induced Airway Eosinophilia
  389. Lack of evidence of a significant association between HLA-DR, DQ and DP genotypes and atopy in families with HDM allergy
  390. Innate immunity: Mast cells in the front line
  391. Genetics of Asthma: What's New?
  392. Genetics of Asthma and Bronchial Hyperresponsiveness