All Stories

  1. Inactivation of CDK4/6, CDK2, and ERK in G1-phase triggers differentiation commitment
  2. High fat diet but not glucocorticoid-induced obesity results in fatty liver
  3. Inactivation of CDK4/6, CDK2, and ERK in G1-phase triggers differentiation commitment
  4. Context-dependent regulation of lipid accumulation in adipocytes by a HIF1α-PPARγ feedback network
  5. Early enforcement of cell identity by a functional component of the terminally differentiated state
  6. Cortisol and cardiometabolic disease: a target for advancing health equity
  7. The formation of fat cells is gated by the circadian clock
  8. Dysregulated glucocorticoid circadian rhythms drive obesity without eating more or differently
  9. A dynamic HIF1α- PPARγ circuit controls a paradoxical adipocyte regulatory landscape
  10. Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle
  11. Early enforcement of cell identity by a functional component of the terminally differentiated state
  12. Flattening of diurnal glucocorticoid oscillations causes Cd36 and insulin-mediated obesity
  13. Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility
  14. Expression variation and covariation impair analog and enable binary signaling control
  15. A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation
  16. Heterogeneous Ribosomes Preferentially Translate Distinct Subpools of mRNAs Genome-wide
  17. Using SRM-MS to quantify nuclear protein abundance differences between adipose tissue depots of insulin-resistant mice
  18. A dynamic picture of protein behavior in cells
  19. Measuring Gli2 Phosphorylation by Selected Reaction Monitoring Mass Spectrometry
  20. The Proteome of Cholesteryl-Ester-Enriched Versus Triacylglycerol-Enriched Lipid Droplets
  21. Controlling low rates of cell differentiation through noise and ultrahigh feedback
  22. Gli Protein Activity Is Controlled by Multisite Phosphorylation in Vertebrate Hedgehog Signaling
  23. The E3 Ubiquitin Ligase UBE3C Enhances Proteasome Processivity by Ubiquitinating Partially Proteolyzed Substrates
  24. Consecutive Positive Feedback Loops Create a Bistable Switch that Controls Preadipocyte-to-Adipocyte Conversion
  25. Neuropilins are positive regulators of Hedgehog signal transduction
  26. Parallel adaptive feedback enhances reliability of the Ca 2+ signaling system
  27. Comprehensive Identification of PIP3-Regulated PH Domains from C. elegans to H. sapiens by Model Prediction and Live Imaging
  28. Rab10, a Target of the AS160 Rab GAP, Is Required for Insulin-Stimulated Translocation of GLUT4 to the Adipocyte Plasma Membrane
  29. siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptake
  30. Fluorescence imaging of signaling networks
  31. Parallel Single-Cell Monitoring of Receptor-Triggered Membrane Translocation of a Calcium-Sensing Protein Module
  32. Control of astrocyte Ca2+ oscillations and waves by oscillating translocation and activation of protein kinase C
  33. Localized Biphasic Changes in Phosphatidylinositol-4,5-Bisphosphate at Sites of Phagocytosis
  34. Spatial Sensing in Fibroblasts Mediated by 3′ Phosphoinositides
  35. Molecular memory by reversible translocation of calcium/calmodulin-dependent protein kinase II
  36. A versatile microporation technique for the transfection of cultured CNS neurons
  37. CaMKIIβ Functions As an F-Actin Targeting Module that Localizes CaMKIIα/β Heterooligomers to Dendritic Spines
  38. Green Fluorescent Protein (GFP)-tagged Cysteine-rich Domains from Protein Kinase C as Fluorescent Indicators for Diacylglycerol Signaling in Living Cells