All Stories

  1. Mycobacteria Amplicon Sequencing Tool: automated resistance prediction and lineage classification for Mycobacterium tuberculosis

    Article • Microbiology Resource Announcements, April 2026, ASM Journals

    Jennifer Guthrie

  2. Population structure of Mycobacterium avium subsp. hominissuis provides new insights into genomic evolution

    Article • Microbial Genomics, November 2025, Society for General Microbiology

    Jennifer Guthrie

  3. Social Determinants and Community-Level Risk Factors in CA-MRSA Transmission Among Disadvantaged Populations in North America: A Scoping Review

    Article • Epidemiology and Infection, October 2025, Cambridge University Press

    Jennifer Guthrie

  4. Genomic Epidemiology of Mycobacterium abscessus on the Island of Montréal Is Not Suggestive of Health Care-Associated Person-to-Person Transmission

    Article • The Journal of Infectious Diseases, August 2024, Oxford University Press (OUP)

    Jennifer Guthrie

  5. A data compendium associating the genomes of 12,289 Mycobacterium tuberculosis isolates with quantitative resistance phenotypes to 13 antibiotics

    Article • PLoS Biology, August 2022, PLOS

    Jennifer Guthrie, Dr Sabira Tahseen

  6. Genome-wide association studies of global Mycobacterium tuberculosis resistance to 13 antimicrobials in 10,228 genomes identify new resistance mechanisms

    Article • PLoS Biology, August 2022, PLOS

    Jennifer Guthrie, Daniel Wilson

  7. Minos: variant adjudication and joint genotyping of cohorts of bacterial genomes

    Article • Genome Biology, July 2022, Springer Science + Business Media

    Jennifer Guthrie

  8. The Dataharmonizer: a Tool for Faster Data Harmonization, Validation, Aggregation, and Analysis of Pathogen Genomics Contextual Information

    Article • June 2022, MDPI AG

    Jennifer Guthrie

  9. A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates

    Article • eLife, May 2022, eLife

    Paolo Miotto, Jennifer Guthrie

  10. The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

    Article • The Lancet Microbe, April 2022, Elsevier

    Paolo Miotto, Dr. Jaime Robledo, Jennifer Guthrie, Dr Sabira Tahseen

  11. Epidemiological cut-off values for a 96-well broth microdilution plate for high-throughput research antibiotic susceptibility testing ofM. tuberculosis

    Article • European Respiratory Journal, March 2022, European Respiratory Society (ERS)

    Philip Fowler, Jennifer Guthrie, Dr Sabira Tahseen

  12. Highly divergent white-tailed deer SARS-CoV-2 with potential deer-to-human transmission

    Article • February 2022, Cold Spring Harbor Laboratory Press

    Jennifer Guthrie

  13. Real-Time RT-PCR Allelic Discrimination Assay for Detection of N501Y Mutation in the Spike Protein of SARS-CoV-2 Associated with B.1.1.7 Variant of Concern

    Article • Microbiology Spectrum, February 2022, ASM Journals

    Jennifer Guthrie

  14. Characteristics of SARS-CoV-2 testing for rapid diagnosis of COVID-19 during the initial stages of a global pandemic

    Article • PLOS One, July 2021, PLOS

    Jennifer Guthrie

  15. Coronavirus Disease 2019 (COVID-19) Outbreak Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) P.1 Lineage in a Long-Term Care Home After Implementation of a Vaccination Program—Ontario, Canada, April–May 2021

    Article • Clinical Infectious Diseases, July 2021, Oxford University Press (OUP)

    Jennifer Guthrie

  16. Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada

    Article • mSphere, June 2021, ASM Journals

    Jennifer Guthrie

  17. Adverse Outcomes Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Variant B.1.351 Infection in Vaccinated Residents of a Long-Term Care Home, Ontario, Canada

    Article • Clinical Infectious Diseases, June 2021, Oxford University Press (OUP)

    Jennifer Guthrie

  18. Detection of the novel SARS-CoV-2 European lineage B.1.177 in Ontario, Canada

    Article • Journal of Clinical Virology Plus, June 2021, Elsevier

    Jennifer Guthrie

  19. Investigation of a severe SARS-CoV-2 outbreak in a long-term care home early in the pandemic

    Article • Canadian Medical Association Journal, May 2021, Canadian Medical Association (CMA)

    Jennifer Guthrie

  20. Prevalence of Co-Infections with Respiratory Viruses in Individuals Investigated for SARS-CoV-2 in Ontario, Canada

    Article • Viruses, January 2021, MDPI AG

    Jennifer Guthrie

  21. Detection of the Novel SARS-CoV-2 European Lineage B.1.177 in Ontario, Canada

    Article • December 2020, Cold Spring Harbor Laboratory Press

    Jennifer Guthrie

  22. Using Whole Genome Sequencing to Determine the Timing of Secondary Tuberculosis in British Columbia, Canada

    Article • Clinical Infectious Diseases, August 2020, Oxford University Press (OUP)

    Jennifer Guthrie

  23. Genomic Epidemiology of Invasive Methicillin-Resistant Staphylococcus aureus Infections Among Hospitalized Individuals in Ontario, Canada

    Article • The Journal of Infectious Diseases, May 2020, Oxford University Press (OUP)

    Jennifer Guthrie

  24. Comparison of routine field epidemiology and whole genome sequencing to identify tuberculosis transmission in a remote setting

    Article • Epidemiology and Infection, January 2020, Cambridge University Press

    Jennifer Guthrie

  25. Whole genome sequencing of Mycobacterium tuberculosis: current standards and open issues

    Article • Nature Reviews Microbiology, June 2019, Springer Science + Business Media

    Jennifer Guthrie, Paolo Miotto

  26. The problem with defining foreign birth as a risk factor in tuberculosis epidemiology studies

    Article • PLOS One, April 2019, PLOS

    Jennifer Guthrie

  27. Universal genotyping reveals province-level differences in the molecular epidemiology of tuberculosis

    Article • PLOS One, April 2019, PLOS

    Jennifer Guthrie

  28. Whole genome sequencing for improved understanding of Mycobacterium tuberculosis transmission in a remote circumpolar region

    Article • Epidemiology and Infection, January 2019, Cambridge University Press

    Jennifer Guthrie

  29. Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, September 2018, New England Journal of Medicine (NEJM/MMS)

    Paolo Miotto, Jennifer Guthrie, Caroline Allix-Béguec, Dr Sabira Tahseen

  30. Genotyping and Whole Genome Sequencing to Identify Tuberculosis Transmission to Pediatric Patients in British Columbia, Canada, 2005–2014

    Article • The Journal of Infectious Diseases, May 2018, Oxford University Press (OUP)

    Jennifer Guthrie

  31. Universal Genotyping for Tuberculosis Prevention Programs: a 5-Year Comparison with On-Request Genotyping

    Article • Journal of Clinical Microbiology, March 2018, ASM Journals

    Jennifer Guthrie

  32. Molecular Epidemiology of Tuberculosis in British Columbia, Canada: A 10-Year Retrospective Study

    Article • Clinical Infectious Diseases, October 2017, Oxford University Press (OUP)

    Jennifer Guthrie

  33. WGS virulence factor typing for pertussis

    Article • Journal of Clinical Microbiology, February 2017, ASM Journals

    Alex Marchand-Austin, Jennifer Guthrie

  34. Self-rated health and reasons for non-vaccination against seasonal influenza in Canadian adults with asthma

    Article • PLOS One, February 2017, PLOS

    Jennifer Guthrie

  35. A brief primer on genomic epidemiology: lessons learned fromMycobacterium tuberculosis

    Article • Annals of the New York Academy of Sciences, December 2016, Wiley

    Jennifer Guthrie

  36. Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages

    Article • Nature Genetics, October 2016, Springer Science + Business Media

    Jennifer Guthrie, Dr Valeriu Crudu, Willy SSENGOOBA

  37. Technology and tuberculosis control: the OUT-TB Web experience

    Article • Journal of the American Medical Informatics Association, September 2016, Oxford University Press (OUP)

    Jennifer Guthrie

  38. Accelerating tuberculosis elimination in low-incidence settings: the role of genomics

    Article • European Respiratory Journal, November 2015, European Respiratory Society (ERS)

    Jennifer Guthrie

  39. Culture-Positive Pediatric Tuberculosis in Toronto, Ontario

    Article • The Pediatric Infectious Disease Journal, September 2015, Wolters Kluwer Health

    Jennifer Guthrie

  40. Marked Microevolution of a Unique Mycobacterium tuberculosis Strain in 17 Years of Ongoing Transmission in a High Risk Population

    Article • PLOS One, November 2014, PLOS

    Jennifer Guthrie

  41. Whole-Genome Sequencing of the Mycobacterium tuberculosis Manila Sublineage Results in Less Clustering and Better Resolution than Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat (MIRU-VNTR) Typing and Spoligotyping

    Article • Journal of Clinical Microbiology, July 2014, ASM Journals

    Jennifer Guthrie

  42. Profiling of rpoB Mutations and MICs for Rifampin and Rifabutin in Mycobacterium tuberculosis

    Article • Journal of Clinical Microbiology, April 2014, ASM Journals

    Dr Roberto G Melano, Jennifer Guthrie

  43. Epidemiological evaluation of spatiotemporal and genotypic clustering of Mycobacterium tuberculosis in Ontario, Canada

    Article • The International Journal of Tuberculosis and Lung Disease, October 2013, International Union Against Tuberculosis and Lung Disease

    Jennifer Guthrie

  44. Reply to “Role ofrpsAGene Sequencing in Diagnosis of Pyrazinamide Resistance”

    Article • Journal of Clinical Microbiology, December 2012, ASM Journals

    Jennifer Guthrie

  45. Gene Sequencing for Routine Verification of Pyrazinamide Resistance in Mycobacterium tuberculosis: a Role for pncA but Not rpsA

    Article • Journal of Clinical Microbiology, August 2012, ASM Journals

    Jennifer Guthrie

  46. Evaluation of Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat Genotyping as Performed in Laboratories in Canada, France, and the United States

    Article • Journal of Clinical Microbiology, April 2012, ASM Journals

    Jennifer Guthrie, Caroline Allix-Béguec

  47. Dispersal of Mycobacterium tuberculosis via the Canadian fur trade

    Article • Proceedings of the National Academy of Sciences, April 2011, Proceedings of the National Academy of Sciences

    Jennifer Guthrie

  48. Analytical and clinical validation of novel real-time reverse transcriptase–polymerase chain reaction assays for the clinical detection of swine-origin H1N1 influenza viruses

    Article • Diagnostic Microbiology and Infectious Disease, February 2011, Elsevier

    Dr Roberto G Melano, Jennifer Guthrie

  49. Crystal structure of a truncated urease accessory protein UreF from Helicobacter pylori

    Article • Proteins Structure Function and Bioinformatics, August 2010, Wiley

    Jennifer Guthrie, Robert Hausinger

  50. Evaluation of Specificity of BP3385 for Bordetella pertussis Detection

    Article • Journal of Clinical Microbiology, July 2010, ASM Journals

    Jennifer Guthrie

  51. Novel Duplex Real-Time PCR Assay Detects Bordetella holmesii in Specimens from Patients with Pertussis-Like Symptoms in Ontario, Canada

    Article • Journal of Clinical Microbiology, February 2010, ASM Journals

    Jennifer Guthrie

  52. Sequence- and activity-based screening of microbial genomes for novel dehalogenases

    Article • Microbial Biotechnology, November 2009, Wiley

    Jennifer Guthrie

  53. Mycobacterium tuberculosis in Ontario, Canada: Insights from IS6110 Restriction Fragment Length Polymorphism and Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat Genotyping

    Article • Journal of Clinical Microbiology, June 2009, ASM Journals

    Jennifer Guthrie

  54. Use of Bordetella pertussis BP3385 To Establish a Cutoff Value for an IS481-Targeted Real-Time PCR Assay

    Article • Journal of Clinical Microbiology, September 2008, ASM Journals

    Jennifer Guthrie

  55. In situ proteolysis for protein crystallization and structure determination

    Article • Nature Chemical Biology, November 2007, Springer Science + Business Media

    Jennifer Guthrie, Dr Wladek Minor

  56. Chitinase production during interaction of Trichoderma aggressivum and Agaricus bisporus

    Article • Canadian Journal of Microbiology, October 2006, Canadian Science Publishing

    Jennifer Guthrie

  57. An improved method for detection and quantification of chitinase activities

    Article • Canadian Journal of Microbiology, June 2005, Canadian Science Publishing

    Jennifer Guthrie