All Stories

  1. Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens

    Article • Proceedings of the National Academy of Sciences, September 2020, Proceedings of the National Academy of Sciences

    Hamish McWilliam, Dr Jeffrey Mak

  2. Artificially induced MAIT cells inhibit M. bovis BCG but not M. tuberculosis during in vivo pulmonary infection

    Article • Scientific Reports, August 2020, Springer Science + Business Media

    Dr Jeffrey Mak

  3. CXCL16 Stimulates Antigen-Induced MAIT Cell Accumulation but Trafficking During Lung Infection Is CXCR6-Independent

    Article • Frontiers in Immunology, August 2020, Frontiers

    Dr Jeffrey Mak

  4. Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

    Article • Science Immunology, July 2020, American Association for the Advancement of Science

    Dr Jeffrey Mak

  5. Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli

    Article • PLoS Biology, June 2020, PLOS

    Dr Jeffrey Mak

  6. The molecular basis underpinning the potency and specificity of MAIT cell antigens

    Article • Nature Immunology, March 2020, Springer Science + Business Media

    Dr Jeffrey Mak

  7. MAIT Cells Promote Tumor Initiation, Growth, and Metastases via Tumor MR1

    Article • Cancer Discovery, December 2019, American Association for Cancer Research (AACR)

    Dr Jeffrey Mak

  8. Computer Modelling and Synthesis of Deoxy and Monohydroxy Analogues of a Ribitylaminouracil Bacterial Metabolite that Potently Activates Human T Cells

    Article • Chemistry - A European Journal, December 2019, Wiley

    Dr Jeffrey Mak

  9. A divergent transcriptional landscape underpins the development and functional branching of MAIT cells

    Article • Science Immunology, November 2019, American Association for the Advancement of Science

    Dr Jeffrey Mak, Shalin Naik

  10. IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

    Article • Science Immunology, November 2019, American Association for the Advancement of Science

    Dr Jeffrey Mak

  11. MAIT Cells Upregulate α4β7 in Response to Acute Simian Immunodeficiency Virus/Simian HIV Infection but Are Resistant to Peripheral Depletion in Pigtail Macaques

    Article • The Journal of Immunology, February 2019, The American Association of Immunologists

    Dr Jeffrey Mak

  12. MAIT cells protect mice lungs against infection by the bacteria Legionella longbeachae

    Article • Nature Communications, August 2018, Springer Science + Business Media

    Dr Jeffrey Mak

  13. An overview on the identification of MAIT cell antigens

    Article • Immunology and Cell Biology, May 2018, Wiley

    Dr Jeffrey Mak

  14. Recipient mucosal-associated invariant T cells control GVHD within the colon

    Article • Journal of Clinical Investigation, April 2018, American Society for Clinical Investigation

    Dr Jeffrey Mak

  15. Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in ChronicHelicobacter pyloriInfection

    Article • The Journal of Immunology, January 2018, The American Association of Immunologists

    Dr Jeffrey Mak

  16. Stereoelectronic Effects on Dienophile Separation Influence the Diels-Alder Synthesis of Molecular Clefts

    Article • European Journal of Organic Chemistry, December 2017, Wiley

    Dr Jeffrey Mak

  17. Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells

    Article • Nature Communications, March 2017, Nature

    Dr Jeffrey Mak

  18. Drugs and drug-like molecules can modulate the function of mucosal-associated invariant T cells

    Article • Nature Immunology, February 2017, Nature

    Dr Jeffrey Mak, Professor Anthony W Purcell

  19. PAR2 Modulators Derived from GB88

    Article • ACS Medicinal Chemistry Letters, December 2016, American Chemical Society (ACS)

    Dr Jeffrey Mak

  20. Recognition of Vitamin B Precursors and Byproducts by Mucosal Associated Invariant T Cells

    Article • Journal of Biological Chemistry, October 2015, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr Jeffrey Mak

  21. Thiazoles in Peptides and Peptidomimetics

    Article • January 2015, Springer Science + Business Media

    Dr Jeffrey Mak

  22. Naturstoffe mit Anti-Bredt- und Brückenkopf-Doppelbindung

    Article • Angewandte Chemie, November 2014, Wiley

    Dr Jeffrey Mak

  23. Natural Products with Anti-Bredt and Bridgehead Double Bonds

    Article • Angewandte Chemie International Edition, November 2014, Wiley

    Dr Jeffrey Mak

  24. T-cell activation by transitory neo-antigens derived from distinct microbial pathways

    Article • Nature, April 2014, Nature

    Dr Jeffrey Mak

  25. Total Synthesis of (-)-Neovibsanin G and (-)-14-epi-Neovibsanin G: Towards the Synthesis of 15-O-Methylneovibsanin F and 14-epi-15-O-Methylneovibsanin F

    Article • European Journal of Organic Chemistry, February 2012, Wiley

    Dr Jeffrey Mak

  26. Chemical synthesis of structurally elaborate compounds from the viburnum plant species

    Article • Chemical Communications, January 2012, Royal Society of Chemistry

    Dr Jeffrey Mak

  27. Key achievements in the total synthesis of vibsane-type diterpenoids

    Article • Natural Product Reports, January 2012, Royal Society of Chemistry

    Dr Jeffrey Mak

  28. Inhibition of purple acid phosphatase with α-alkoxynaphthylmethylphosphonic acids

    Article • Bioorganic & Medicinal Chemistry Letters, January 2009, Elsevier

    Dr Jeffrey Mak