Professor James Keane Bashkin

All Stories

1. Article

   Effects of Head Group Substitution on Large Antiviral Polyamide-DNA Binding Kinetics
   Professor James Keane Bashkin
2. Article

   Kinetics of DNA-polyamide binding for a large polyamide with antiviral properties.
   Professor James Keane Bashkin
3. Article

   Large polyamides bind to DNA only by entropy and bind with higher than 1:1 stoichiometries.
   Professor James Keane Bashkin
4. Article

   Working to control the behavior of cancer-related protein PU.1 and its DNA-binding properties.
   Professor James Keane Bashkin
5. Article

   In the free energy of large polyamide-DNA binding, there is no productive enthalpic contribution
   Professor James Keane Bashkin
6. Article

   A small molecule protects against negative strand RNA virus Vesicular Stomatitis Virus.
   Professor James Keane Bashkin
7. Article

   Improved drug candidates for cancer-causing human papillomavirus.
   Professor James Keane Bashkin
8. Article

   The title compound is a precursor to chemicals that protect automobile tires from oxidation.
   Professor James Keane BashkinChemist Dr Syed Ahmad Raza Bokhari
9. Article

   Interactions of two large antiviral polyamides with the long control region of HPV16
   Professor James Keane Bashkin
10. Article

    Improved antiviral activity of a polyamide against high-risk human papillomavirus via N-terminal guanidinium substitution
    Professor James Keane Bashkin
11. Article

    What is the antiviral potential of pyrrole-imidazole polyamides?
    Professor James Keane Bashkin
12. Article

    134 Large antiviral polyamide-DNA interactions
    Professor James Keane Bashkin
13. Article

    Heterogeneous dynamics in DNA site discrimination by the structurally homologous DNA-binding domains of ETS-family transcription factors
    Professor James Keane Bashkin
14. Article

    Unraveling the Structural, Dynamic, Thermodynamic, and Kinetic Heterogeneity in DNA Site Recognition by Structurally Homologous ETS Transcription Factors
    Professor James Keane Bashkin
15. Article

    Binding studies of a large antiviral polyamide to a natural HPV sequence
    Professor James Keane Bashkin
16. Article

    Modulation of DNA–polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics
    Professor James Keane BashkinProfessor W. David Wilson
17. Article

    DNA Binding Polyamides and the Importance of DNA Recognition in their use as Gene-Specific and Antiviral Agents
    Dr Chris FisherProfessor James Keane Bashkin
18. Article

    DNA Damage Repair Genes Controlling Human Papillomavirus (HPV) Episome Levels under Conditions of Stability and Extreme Instability
    Professor James Keane BashkinDr Chris Fisher
19. Article

    Mapping small DNA ligand hydroxyl radical footprinting and affinity cleavage products for capillary electrophoresis
    Professor James Keane Bashkin
20. Article

    Promoter scanning of the human COX-2 gene with 8-ring polyamides: Unexpected weakening of polyamide–DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine
    Professor James Keane Bashkin
21. Article

    Human Papillomavirus Episome Stability Is Reduced by Aphidicolin and Controlled by DNA Damage Response Pathways
    Professor James Keane BashkinDr Chris Fisher
22. Article

    Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature
    Professor James Keane BashkinProfessor W. David Wilson
23. Article

    DNA binding polyamides and the importance of DNA recognition in their use as gene-specific and antiviral agents
    Professor James Keane Bashkin
24. Article

    69 DNA-binding studies of large antiviral polyamides
    Professor James Keane Bashkin
25. Article

    Correlation of Local Effects of DNA Sequence and Position of β-Alanine Inserts with Polyamide–DNA Complex Binding Affinities and Kinetics
    Professor James Keane Bashkin
26. Article

    Corrigendum to “Fluorescence assay of polyamide–DNA interactions” [Anal. Biochem. 423 (2012) 178–183]
    Professor James Keane Bashkin
27. Article

    Fluorescence assay of polyamide–DNA interactions
    Professor James Keane Bashkin
28. Article

    Long pyrrole-imidazole polyamides cause active elimination of viral HPV DNA.
    Professor James Keane BashkinDr Chris Fisher
29. Article

    Erratum: Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
    Professor James Keane Bashkin
30. Article

    ChemInform Abstract: Synthesis and Characterization of Nucleoside Peptides: Toward Chemical Ribonucleases.
    Professor James Keane Bashkin
31. Article

    ChemInform Abstract: Toward Chemical Ribonucleases. Part 2. Synthesis and Characterization of Nucleoside-Bipyridine Conjugates. Hydrolytic Cleavage of RNA by Their Copper(II) Complexes.
    Professor James Keane Bashkin
32. Article

    ChemInform Abstract: Direct Coupling of Aniline and Nitrobenzene: A New Example of Nucleophilic Aromatic Substitution for Hydrogen.
    Professor James Keane Bashkin
33. Article

    ChemInform Abstract: Inorganic Mimics of Ribonucleases and Ribozymes: From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs.
    Professor James Keane Bashkin
34. Article

    ChemInform Abstract: Precise Control of RNA Cleavage by Ribozyme Mimics.
    Professor James Keane Bashkin
35. Article

    ChemInform Abstract: Synthesis of Reversible Nucleoside Amino Acid Conjugates.
    Professor James Keane Bashkin
36. Article

    Compounds Designed to Bind Conserved Regions of Human Papillomavirus (HPV) DNA show Broad-spectrum Activity Against High-risk Genotypes
    Professor James Keane Bashkin
37. Article

    Effects of Anti-human Papillomavirus (HPV) Disease Agents on HPV Episome Levels In Vitro: Cidofovir, Podophyllotoxin, and Pyrrole–Imidazole Polyamides
    Professor James Keane Bashkin
38. Article

    Ion-exchange chromatography followed by ESI-MS for quantitative analysis of sugar monophosphates from glucose catabolism
    Professor James Keane Bashkin
39. Article

    Synthesis and Evaluation of RNA Transesterification Efficiency Using Stereospecific Serinol-Terpyridine Conjugates
    Professor James Keane Bashkin
40. Article

    Controlling the intracellular localization of fluorescent polyamide analogues in cultured cells
    Professor James Keane Bashkin
41. Article

    Structure of a bacterial quorum-sensing transcription factor complexed with autoinducer-type pheromone and DNA
    Professor James Keane Bashkin
42. Article

    Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
    Professor James Keane Bashkin
43. Article

    Editorial
    Professor James Keane Bashkin
44. Article

    Enhancing Sequence-Specific Cleavage of RNA within a Duplex Region:  Incorporation of 1,3-Propanediol Linkers into Oligonucleotide Conjugates of Serinol−Terpyridine
    Professor James Keane Bashkin
45. Article

    Efficient new ribozyme mimics: direct mapping of molecular design principles from small molecules to macromolecular, biomimetic catalysts
    Professor James Keane Bashkin
46. Article

    Probing the importance of electrostatic interactions of Ce(iii) with the phosphodiester backbone during transesterification using methyl phosphonates
    Professor James Keane Bashkin
47. Article

    CarbohydratesA Hostile Scientific Frontier Becomes Friendlier
    Professor James Keane Bashkin
48. Article

    De novo synthesis of artificial ribonucleases with benign metal catalysts
    Professor James Keane Bashkin
49. Article

    Hydrolysis of phosphates, esters and related substrates by models of biological catalysts
    Professor James Keane Bashkin
50. Article

    Catalytic Hydrolysis of Adenosine 2‘,3‘-Cyclic Monophosphate by CuII Terpyridine
    Professor James Keane Bashkin
51. Article

    Editorial
    Professor James Keane Bashkin
52. Article

    Taking green chemistry from the laboratory to chemical plant
    Professor James Keane Bashkin
53. Article

    Terpyridyl derivatives as bifunctional chelates: synthesis and crystal structures of 4′-[2-(1,3-dioxolan-2-yl)ethylsulfanyl]-2,2′∶6′,2″-terpyridine and chloro(4′-methylsulfanyl-2,2′∶6′,2″-terpyridine)gold(III) bis(trifluoromethanesulfonate) †
    Professor James Keane Bashkin
54. Article

    Profile: James Bashkin
    Professor James Keane Bashkin
55. Article

    Introduction to RNA/DNA Cleavage
    Professor James Keane Bashkin
56. Article

    Inorganic Mimics of Ribonucleases and Ribozymes:  From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs
    Professor James Keane Bashkin
57. Article

    Analysis of Iron in Ferritin, the Iron-Storage Protein: A General Chemistry Experiment
    Professor James Keane Bashkin
58. Article

    Precise control of RNA cleavage by ribozyme mimics
    Professor James Keane Bashkin
59. Article

    Transesterification of RNA by Cu(II) terpyridine
    Professor James Keane Bashkin
60. Article

    Modulation of RNase H activity by modified DNA probes: Major groove vs minor groove effects
    Professor James Keane Bashkin
61. Article

    DNA enzymes: New-found chemical reactivity
    Professor James Keane Bashkin
62. Article

    Hydrogenation of dinitrosarcophagine Co(III); the crystal structures of Co(II) and Co(III) complexes of diaminosarcophagine
    Professor James Keane Bashkin
63. Article

    The Embedded Ribonucleotide Assay:  A Chimeric Substrate for Studying Cleavage of RNA by Transesterification
    Professor James Keane Bashkin
64. Article

    Ribozyme Mimics For Catalytic Antisense Strategies
    Professor James Keane Bashkin
65. Article

    Synthesis and Characterization of Cobalt-Cage Complexes with Pendant Phenol Groups
    Professor James Keane Bashkin
66. Article

    Building Blocks for Ribozyme Mimics:  Conjugates of Terpyridine and Bipyridine with Nucleosides
    Professor James Keane Bashkin
67. Article

    Ribozyme mimics as catalytic antisense reagents
    Professor James Keane Bashkin
68. Article

    Sequence-Specific Cleavage of HIV mRNA by a Ribozyme Mimic
    Professor James Keane Bashkin
69. Article

    The Role of Metals in the Hydrolytic Cleavage of DNA and RNA
    Professor James Keane Bashkin
70. Article

    Mechanistic studies of RNA strand cleavage: Hydrolysis of cAMP with copper(II)terpyridine
    Professor James Keane Bashkin
71. Article

    RNA Hydrolysis by Cu(II) Complexes: Toward Synthetic Ribonucleases and Ribozymes
    Professor James Keane Bashkin
72. Article

    Catalytic hydrolysis of 2′,3′-cyclic adenosine monophosphate by aqua(2,2′:6′,2″-terpyridine)copper(II): breakdown of the analogy between activated phosphodiesters and RNA
    Professor James Keane Bashkin
73. Article

    The direct coupling of aniline and nitrobenzene: a new example of nucleophilic aromatic substitution for hydrogen
    Professor James Keane Bashkin
74. Article

    RNA hydrolysis by Cu(II) complexes: Toward synthetic ribonucleases and ribozymes
    Professor James Keane Bashkin
75. Article

    Synthesis and characterization of oligonucleotide peptides
    Professor James Keane Bashkin
76. Article

    Toward Chemical Ribonucleases. 2. Synthesis and Characterization of Nucleoside-Bipyridine Conjugates. Hydrolytic Cleavage of RNA by Their Copper(II) Complexes
    Professor James Keane Bashkin
77. Article

    Electronic structure of icosahedral cobalt-sulfur clusters
    Professor James Keane Bashkin
78. Article

    Oxygen-stable ferrocene reference electrodes
    Professor James Keane Bashkin
79. Article

    Synthesis and characterization of nucleoside peptides: toward chemical ribonucleases. 1
    Professor James Keane Bashkin
80. Article

    Hydrolysis of RNA by transition metal complexes
    Professor James Keane Bashkin
81. Article

    Phosphine cleavage of iron(III)-bridged double cubanes: a new route to MoFe3S4 single cubanes
    Professor James Keane Bashkin
82. Article

    [Fe2S2(CO)6]2− as a cluster precursor: synthesis and structure of [MoFe3S6(CO)6]2− and oxidative decarbonylation to a persulfide-bridged MoFe3S4 double cubane
    Professor James Keane Bashkin
83. Article

    A new inorganic ring system: planar Fe3(.mu.2-SR)3 in [Fe3(SR)3X6]3--synthesis, structures, and solution conformation and equilibrium
    Professor James Keane Bashkin
84. Article

    Synthesis and structural characterisation of [(Ph3P)AuCo(CO)3(PPh3)]
    Professor James Keane Bashkin
85. Article

    The clusters [Co8S6(SPh)8]4-,5-: preparations, properties, and structural relationship of near-cubic Co8(.mu.4-S)6 cores to the clusters in synthetic pentlandite
    Professor James Keane Bashkin
86. Article

    Persulfide-bridged iron-molybdenum-sulfur clusters of biological relevance: two synthetic routes and the structures of intermediate and product clusters
    Professor James Keane Bashkin
87. Article

    Hexakis(trimethylphosphine)molybdenum chemistry: dinitrogen, ethylene, butadiene, η-cyclopentadienyl, and related derivatives
    Professor James Keane Bashkin
88. Article

    Molybdenum atom ligand substitution reactions of molybdenum-iron-sulfur (MoFe3S4) cubane-type clusters: synthesis and structures of clusters containing molybdenum-bound pseudosubstrates of nitrogenase
    Professor James Keane Bashkin
89. Article

    A new route to chiral bis-tertiary phosphine ligands: synthesis, resolution, and crystal structure of trans-bis-1,2-(diphenylphosphino)-cyclopentane and the nickel adduct NiBr2[trans-1,2-(PPh2)2C5H8]
    Professor James Keane Bashkin
90. Article

    Inter-relationships in molybdenocene dimer chemistry: a convenient synthesis of bis-η-cyclopentadienyldichloromolybdenum
    Professor James Keane Bashkin
91. Article

    Synthesis of hexakis (trimethylphosphine) molybdenum using molybdenum atoms and its X-ray crystal structure
    Professor James Keane Bashkin
92. Article

    Synthetic pathways in binuclear molybdenum chemistry: µ-acetato-, chloro-, and tertiary phosphine derivatives; X-ray structure determination of trans-[{MoCl(PBun3)(µ-O2CMe)}2]
    Professor James Keane Bashkin
93. Article

    Synthesis, structure, and reactions of a new dimer of molybdenocene, and related bi- and tri-nuclear compounds; molecular structures of [H(η5-C5H5)2Mo(µ-σ:η5-C5H4)Mo(η5...
    Professor James Keane Bashkin
94. Article

    Bis(trimethyltin)bis-(η-toluene)-hafnium and -zirconium; X-ray crystal structure of the hafnium compound
    Professor James Keane Bashkin