All Stories
- Kinetics of DNA-polyamide binding for a large polyamide with antiviral properties.
Article
- Large polyamides bind to DNA only by entropy and bind with higher than 1:1 stoichiometries.
Article
- Working to control the behavior of cancer-related protein PU.1 and its DNA-binding properties.
Article
- In the free energy of large polyamide-DNA binding, there is no productive enthalpic contribution
Article
- A small molecule protects against negative strand RNA virus Vesicular Stomatitis Virus.
Article
- Improved drug candidates for cancer-causing human papillomavirus.
Article
- The title compound is a precursor to chemicals that protect automobile tires from oxidation.
Article
- Interactions of two large antiviral polyamides with the long control region of HPV16
Article
- Improved antiviral activity of a polyamide against high-risk human papillomavirus via N-terminal guanidinium substitution
Article
- What is the antiviral potential of pyrrole-imidazole polyamides?
Article
- 134 Large antiviral polyamide-DNA interactions
Article
- Heterogeneous dynamics in DNA site discrimination by the structurally homologous DNA-binding domains of ETS-family transcription factors
Article
- Unraveling the Structural, Dynamic, Thermodynamic, and Kinetic Heterogeneity in DNA Site Recognition by Structurally Homologous ETS Transcription Factors
Article
- Binding studies of a large antiviral polyamide to a natural HPV sequence
Article
- Modulation of DNA–polyamide interaction by β-alanine substitutions: a study of positional effects on binding affinity, kinetics and thermodynamics
Article
- DNA Binding Polyamides and the Importance of DNA Recognition in their use as Gene-Specific and Antiviral Agents
Article
- DNA Damage Repair Genes Controlling Human Papillomavirus (HPV) Episome Levels under Conditions of Stability and Extreme Instability
Article
- Mapping small DNA ligand hydroxyl radical footprinting and affinity cleavage products for capillary electrophoresis
- Promoter scanning of the human COX-2 gene with 8-ring polyamides: Unexpected weakening of polyamide–DNA binding and selectivity by replacing an internal N-Me-pyrrole with β-alanine
Article
- Human Papillomavirus Episome Stability Is Reduced by Aphidicolin and Controlled by DNA Damage Response Pathways
Article
- Different thermodynamic signatures for DNA minor groove binding with changes in salt concentration and temperature
Article
- DNA binding polyamides and the importance of DNA recognition in their use as gene-specific and antiviral agents
Article
- 69 DNA-binding studies of large antiviral polyamides
Article
- Correlation of Local Effects of DNA Sequence and Position of β-Alanine Inserts with Polyamide–DNA Complex Binding Affinities and Kinetics
Article
- Corrigendum to “Fluorescence assay of polyamide–DNA interactions” [Anal. Biochem. 423 (2012) 178–183]
- Fluorescence assay of polyamide–DNA interactions
Article
- Long pyrrole-imidazole polyamides cause active elimination of viral HPV DNA.
Article
- Erratum: Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
- ChemInform Abstract: Synthesis and Characterization of Nucleoside Peptides: Toward Chemical Ribonucleases.
Article
- ChemInform Abstract: Toward Chemical Ribonucleases. Part 2. Synthesis and Characterization of Nucleoside-Bipyridine Conjugates. Hydrolytic Cleavage of RNA by Their Copper(II) Complexes.
- ChemInform Abstract: Direct Coupling of Aniline and Nitrobenzene: A New Example of Nucleophilic Aromatic Substitution for Hydrogen.
- ChemInform Abstract: Inorganic Mimics of Ribonucleases and Ribozymes: From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs.
- ChemInform Abstract: Precise Control of RNA Cleavage by Ribozyme Mimics.
- ChemInform Abstract: Synthesis of Reversible Nucleoside Amino Acid Conjugates.
- Compounds Designed to Bind Conserved Regions of Human Papillomavirus (HPV) DNA show Broad-spectrum Activity Against High-risk Genotypes
- Effects of Anti-human Papillomavirus (HPV) Disease Agents on HPV Episome Levels In Vitro: Cidofovir, Podophyllotoxin, and Pyrrole–Imidazole Polyamides
- Ion-exchange chromatography followed by ESI-MS for quantitative analysis of sugar monophosphates from glucose catabolism
Article
- Synthesis and Evaluation of RNA Transesterification Efficiency Using Stereospecific Serinol-Terpyridine Conjugates
- Controlling the intracellular localization of fluorescent polyamide analogues in cultured cells
- Structure of a bacterial quorum-sensing transcription factor complexed with autoinducer-type pheromone and DNA
- Structure of a bacterial quorum-sensing transcription factor complexed with pheromone and DNA
- Editorial
- Enhancing Sequence-Specific Cleavage of RNA within a Duplex Region: Incorporation of 1,3-Propanediol Linkers into Oligonucleotide Conjugates of Serinol−Terpyridine
Article
- Efficient new ribozyme mimics: direct mapping of molecular design principles from small molecules to macromolecular, biomimetic catalysts
Article
- Probing the importance of electrostatic interactions of Ce(iii) with the phosphodiester backbone during transesterification using methyl phosphonates
- CarbohydratesA Hostile Scientific Frontier Becomes Friendlier
Article
- De novo synthesis of artificial ribonucleases with benign metal catalysts
- Hydrolysis of phosphates, esters and related substrates by models of biological catalysts
- Catalytic Hydrolysis of Adenosine 2‘,3‘-Cyclic Monophosphate by CuII Terpyridine
- Editorial
- Taking green chemistry from the laboratory to chemical plant
- Terpyridyl derivatives as bifunctional chelates: synthesis and crystal structures of 4′-[2-(1,3-dioxolan-2-yl)ethylsulfanyl]-2,2′∶6′,2″-terpyridine and chloro(4′-methylsulfanyl-2,2′∶6′,2″-terpyridine)gold(III) bis(trifluoromethanesulfonate) †
- Profile: James Bashkin
- Introduction to RNA/DNA Cleavage
- Inorganic Mimics of Ribonucleases and Ribozymes: From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs
Article
- Analysis of Iron in Ferritin, the Iron-Storage Protein: A General Chemistry Experiment
- Precise control of RNA cleavage by ribozyme mimics
- Transesterification of RNA by Cu(II) terpyridine
- Modulation of RNase H activity by modified DNA probes: Major groove vs minor groove effects
- DNA enzymes: New-found chemical reactivity
- Hydrogenation of dinitrosarcophagine Co(III); the crystal structures of Co(II) and Co(III) complexes of diaminosarcophagine
- The Embedded Ribonucleotide Assay: A Chimeric Substrate for Studying Cleavage of RNA by Transesterification
- Ribozyme Mimics For Catalytic Antisense Strategies
- Synthesis and Characterization of Cobalt-Cage Complexes with Pendant Phenol Groups
- Building Blocks for Ribozyme Mimics: Conjugates of Terpyridine and Bipyridine with Nucleosides
- Ribozyme mimics as catalytic antisense reagents
- Sequence-Specific Cleavage of HIV mRNA by a Ribozyme Mimic
- The Role of Metals in the Hydrolytic Cleavage of DNA and RNA
- Mechanistic studies of RNA strand cleavage: Hydrolysis of cAMP with copper(II)terpyridine
- RNA Hydrolysis by Cu(II) Complexes: Toward Synthetic Ribonucleases and Ribozymes
- Catalytic hydrolysis of 2′,3′-cyclic adenosine monophosphate by aqua(2,2′:6′,2″-terpyridine)copper(II): breakdown of the analogy between activated phosphodiesters and RNA
- The direct coupling of aniline and nitrobenzene: a new example of nucleophilic aromatic substitution for hydrogen
- RNA hydrolysis by Cu(II) complexes: Toward synthetic ribonucleases and ribozymes
- Synthesis and characterization of oligonucleotide peptides
- Toward Chemical Ribonucleases. 2. Synthesis and Characterization of Nucleoside-Bipyridine Conjugates. Hydrolytic Cleavage of RNA by Their Copper(II) Complexes
- Electronic structure of icosahedral cobalt-sulfur clusters
- Oxygen-stable ferrocene reference electrodes
- Synthesis and characterization of nucleoside peptides: toward chemical ribonucleases. 1
- Hydrolysis of RNA by transition metal complexes
- Phosphine cleavage of iron(III)-bridged double cubanes: a new route to MoFe3S4 single cubanes
- [Fe2S2(CO)6]2− as a cluster precursor: synthesis and structure of [MoFe3S6(CO)6]2− and oxidative decarbonylation to a persulfide-bridged MoFe3S4 double cubane
- A new inorganic ring system: planar Fe3(.mu.2-SR)3 in [Fe3(SR)3X6]3--synthesis, structures, and solution conformation and equilibrium
- Synthesis and structural characterisation of [(Ph3P)AuCo(CO)3(PPh3)]
- The clusters [Co8S6(SPh)8]4-,5-: preparations, properties, and structural relationship of near-cubic Co8(.mu.4-S)6 cores to the clusters in synthetic pentlandite
- Persulfide-bridged iron-molybdenum-sulfur clusters of biological relevance: two synthetic routes and the structures of intermediate and product clusters
- Hexakis(trimethylphosphine)molybdenum chemistry: dinitrogen, ethylene, butadiene, η-cyclopentadienyl, and related derivatives
- Molybdenum atom ligand substitution reactions of molybdenum-iron-sulfur (MoFe3S4) cubane-type clusters: synthesis and structures of clusters containing molybdenum-bound pseudosubstrates of nitrogenase
- A new route to chiral bis-tertiary phosphine ligands: synthesis, resolution, and crystal structure of trans-bis-1,2-(diphenylphosphino)-cyclopentane and the nickel adduct NiBr2[trans-1,2-(PPh2)2C5H8]
- Inter-relationships in molybdenocene dimer chemistry: a convenient synthesis of bis-η-cyclopentadienyldichloromolybdenum
- Synthesis of hexakis (trimethylphosphine) molybdenum using molybdenum atoms and its X-ray crystal structure
- Synthetic pathways in binuclear molybdenum chemistry: µ-acetato-, chloro-, and tertiary phosphine derivatives; X-ray structure determination of trans-[{MoCl(PBun3)(µ-O2CMe)}2]
- Synthesis, structure, and reactions of a new dimer of molybdenocene, and related bi- and tri-nuclear compounds; molecular structures of [H(η5-C5H5)2Mo(µ-σ:η5-C5H4)Mo(η5...
- Bis(trimethyltin)bis-(η-toluene)-hafnium and -zirconium; X-ray crystal structure of the hafnium compound