All Stories

  1. Cardiovascular Safety of VIAN‐c4551, an Antiangiogenic Peptide Derived From Vasoinhibin

    Article • Drug Development Research, October 2025, Wiley

    Dr Jakob Triebel

  2. Call for Submissions: Macroprolactinaemia

    Article • September 2025, Yellow Thistle Publishing Ltd

    Dr Jakob Triebel

  3. Relationships Between H2S and OT/OTR Systems in Preeclampsia

    Article • Antioxidants, July 2025, MDPI AG

    Dr Jakob Triebel

  4. Sequencing Report of a Monoclonal Vasoinhibin Antibody

    Article • June 2025, Yellow Thistle Publishing Ltd

    Dr Jakob Triebel

  5. The antiangiogenic peptide VIAN-c4551 inhibits lung melanoma metastasis in mice by reducing pulmonary vascular permeability

    Article • PLOS One, May 2025, PLOS

    Carmen Clapp, Dr Jakob Triebel

  6. Call for Submissions: Prolactin in cardiovascular disease, prolactin reference ranges, and clinical significance of hypo- and hyperprolactinemia 

    Article • May 2025, Yellow Thistle Publishing Ltd

    Dr Jakob Triebel

  7. Vasoinhibin is Generated by the Renin-angiotensin System

    Article • Endocrinology, February 2025, Endocrine Society

    Dr Jakob Triebel

  8. The antiangiogenic peptide VIAN-c4551 inhibits lung melanoma metastasis in mice by reducing pulmonary vascular permeability

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Dr Jakob Triebel

  9. Vasoinhibin is Generated by the Renin-Angiotensin System

    Article • December 2024, Cold Spring Harbor Laboratory Press

    Dr Jakob Triebel

  10. Topical Ophthalmic Administration of VIAN-c4551 Antiangiogenic Peptide for Diabetic Macular Edema: Preclinical Efficacy and Ocular Pharmacokinetics

    Article • September 2024, Cold Spring Harbor Laboratory Press

    Dr Jakob Triebel

  11. Re: Prolactin is a Key Factor for Nonalcoholic Fatty Liver Disease in Obese Children

    Article • Hormone and Metabolic Research, May 2024, Thieme Publishing Group

    Dr Jakob Triebel

  12. Vasoinhibin’s Apoptotic, Inflammatory, and Fibrinolytic Actions Are in a Motif Different From Its Antiangiogenic HGR Motif

    Article • Endocrinology, December 2023, Endocrine Society

    Dr Jakob Triebel

  13. Levosulpiride for the treatment of diabetic macular oedema: a phase 2 randomized clinical trial

    Article • Eye, September 2023, Springer Science + Business Media

    Dr Jakob Triebel

  14. The apoptotic, inflammatory, and fibrinolytic actions of vasoinhibin are in a motif different from its antiangiogenic HGR motif

    Article • August 2023, Cold Spring Harbor Laboratory Press

    Dr Jakob Triebel

  15. Immune activating and inhibiting effects of calcitriol on γδ T cells and NK cells

    Article • Immunobiology, November 2022, Elsevier

    Dr Jakob Triebel

  16. Prolactin and vasoinhibin are endogenous players in diabetic retinopathy revisited

    Article • Frontiers in Endocrinology, September 2022, Frontiers

    Dr Jakob Triebel

  17. New horizons in specific hormone proteolysis

    Article • Trends in Endocrinology and Metabolism, June 2022, Elsevier

    Dr Jakob Triebel

  18. A comparative phylogenetic analysis of prolactin cleavage sites for the generation of vasoinhibin in vertebrates

    Article • General and Comparative Endocrinology, May 2022, Elsevier

    Dr Jakob Triebel

  19. Complement Proteins C5/C5a, Cathepsin D and Prolactin in Chondrocytes: A Possible Crosstalk in the Pathogenesis of Osteoarthritis

    Article • Cells, March 2022, MDPI AG

    Dr Jakob Triebel

  20. Human Placental Tissue Contains A Placental Lactogen–Derived Vasoinhibin

    Article • Journal of the Endocrine Society, February 2022, Endocrine Society

    Dr Jakob Triebel

  21. Sulpiride‐induced hyperprolactinaemia increases retinal vasoinhibin and protects against diabetic retinopathy in rats

    Article • Journal of Neuroendocrinology, January 2022, Wiley

    Dr Jakob Triebel

  22. High Resolution Continuous Elution Electrophoresis for the Evaluation of Low Abundance Serum Proteins

    Article • Clinical Laboratory, January 2022, Clinical Laboratory Publications

    Dr Jakob Triebel

  23. Plasmin generates vasoinhibin-like peptides by cleaving prolactin and placental lactogen

    Article • Molecular and Cellular Endocrinology, December 2021, Elsevier

    Dr Jakob Triebel

  24. Thrombin Cleaves Prolactin Into a Potent 5.6-kDa Vasoinhibin: Implication for Tissue Repair

    Article • Endocrinology, August 2021, Endocrine Society

    Dr Jakob Triebel

  25. The HGR motif is the antiangiogenic determinant of vasoinhibin: implications for a therapeutic orally active oligopeptide

    Article • Angiogenesis, June 2021, Springer Science + Business Media

    Dr Jakob Triebel

  26. Development of Vasoinhibin-Specific Monoclonal Antibodies

    Article • Frontiers in Endocrinology, April 2021, Frontiers

    Dr Jakob Triebel

  27. Time for a New Perspective on Prolactin in Metabolism

    Article • Trends in Endocrinology and Metabolism, February 2020, Elsevier

    Dr Jakob Triebel

  28. Matrix Metalloproteases and Cathepsin D in Human Serum do not Cleave Prolactin to Generate Vasoinhibin

    Article • Clinical Laboratory, January 2020, Clinical Laboratory Publications

    Dr Jakob Triebel

  29. Improving Immunotherapy Against B-Cell Malignancies Using γδ T-Cell–specific Stimulation and Therapeutic Monoclonal Antibodies

    Article • Journal of Immunotherapy, July 2019, Wolters Kluwer Health

    Dr Jakob Triebel

  30. Analysing Point Mutations in Protein Cleavage Sites by Using Enzyme Specificity Matrices

    Article • Frontiers in Endocrinology, May 2019, Frontiers

    Dr Jakob Triebel

  31. Regulator of Angiogenesis and Vascular Function: A 2019 Update of the Vasoinhibin Nomenclature

    Article • Frontiers in Endocrinology, April 2019, Frontiers

    Dr Jakob Triebel

  32. Vasoinhibin comprises a three-helix bundle and its antiangiogenic domain is located within the first 79 residues

    Article • Scientific Reports, November 2018, Springer Science + Business Media

    Dr Jakob Triebel

  33. Basis and Design of a Randomized Clinical Trial to Evaluate the Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema

    Article • Frontiers in Endocrinology, May 2018, Frontiers

    Carmen Clapp, Dr Jakob Triebel

  34. Osteoarthritis and the Complement Cascade

    Article • Clinical Medicine Insights Arthritis and Musculoskeletal Disorders, January 2018, SAGE Publications

    Dr Jakob Triebel

  35. From Bench to Bedside: Translating the Prolactin/Vasoinhibin Axis

    Article • Frontiers in Endocrinology, December 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  36. Human Prolactin Point Mutations and Their Projected Effect on Vasoinhibin Generation and Vasoinhibin-Related Diseases

    Article • Frontiers in Endocrinology, November 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  37. Vasoinhibins May Contribute to Postpartum Depression

    Article • Frontiers in Psychiatry, September 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  38. Percutaneous Closure of Left Atrial Appendage affects Mid-Term Release of MR-proANP

    Article • Scientific Reports, August 2017, Nature

    Dr Jakob Triebel

  39. Commentary: Prolactin Alters Blood Pressure by Modulating the Activity of Endothelial Nitric Oxide Synthase

    Article • Frontiers in Endocrinology, May 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  40. Remarks on the Prolactin Hypothesis of Peripartum Cardiomyopathy

    Article • Frontiers in Endocrinology, April 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  41. Vasoinhibin Serum Levels Are Required to Demonstrate Their Role in Peripartum Cardiomyopathy Etiopathology

    Article • ASAIO Journal, January 2017, Wolters Kluwer Health

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  42. Comment On: Peripartum Cardiomyopathy Treatment with Dopamine Agonist and Subsequent Pregnancy with a Satisfactory Outcome

    Article • Revista Brasileira Ginecologia e Obstetrícia, November 2016, Thieme Publishing Group

    Dr Jakob Triebel, Carmen Clapp

  43. Higher prolactin and vasoinhibin serum levels associated with incidence and progression of retinopathy of prematurity

    Article • Pediatric Research, November 2016, Springer Science + Business Media

    Dr Jakob Triebel, Carmen Clapp

  44. The vasoinhibin solution structure appears unfolded, dynamic, and features aggregation

    Article • Endocrine Abstracts, May 2016, Bioscientifica

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  45. Serum proteases do not cleave prolactin to vasoinhibins at physiological pH

    Article • Endocrine Abstracts, May 2016, Bioscientifica

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  46. Principles of the prolactin/vasoinhibin axis

    Article • AJP Regulatory Integrative and Comparative Physiology, November 2015, American Physiological Society

    Dr Jakob Triebel, Carmen Clapp

  47. C-reactive protein and the acute phase reaction in geriatric patients

    Article • Zeitschrift für Gerontologie und Geriatrie, September 2015, Springer Science + Business Media

    Dr Jakob Triebel

  48. On the Path toward Classifying Hormones of the Vasoinhibin-Family

    Article • Frontiers in Endocrinology, February 2015, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  49. Vitamin D deficiency decreases survival of bacterial meningoencephalitis in mice

    Article • Journal of Neuroinflammation, January 2015, Springer Science + Business Media

    Dr Jakob Triebel

  50. High Prolactin Excretion in Patients with Diabetes Mellitus and Impaired Renal Function

    Article • Clinical Laboratory, January 2015, Clinical Laboratory Publications

    Dr Jakob Triebel, Carmen Clapp

  51. Regulation of Blood Vessels by Prolactin and Vasoinhibins

    Article • December 2014, Springer Science + Business Media

    Dr Jakob Triebel, Carmen Clapp

  52. Vasoinhibins are natural inhibitors of angiogenesis in the vitreous and are impaired in patients with diabetic retinopathy

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  53. Alpha-1-Fetoprotein (AFP) Measurements and the High-Dose Hook Effect

    Article • Clinical Laboratory, January 2014, Clinical Laboratory Publications

    Dr Jakob Triebel

  54. Prolactin promotes normal liver growth, survival, and regeneration in rodents: effects on hepatic IL-6, suppressor of cytokine signaling-3, and angiogenesis

    Article • AJP Regulatory Integrative and Comparative Physiology, October 2013, American Physiological Society

    Dr Jakob Triebel, Carmen Clapp

  55. Prolactin promotes cartilage survival and attenuates inflammation in inflammatory arthritis

    Article • Journal of Clinical Investigation, August 2013, American Society for Clinical Investigation

    Dr Jakob Triebel, Dr. Isabel Méndez, Carmen Clapp

  56. Comment on: Richter et al. Serum Levels of the Adipokine Progranulin Depend on Renal Function. Diabetes Care 2013;36:410-414

    Article • Diabetes Care, May 2013, American Diabetes Association

    Dr Jakob Triebel

  57. Role of IGF‐1 and glycaemic control in diabetic retinopathy

    Article • European Journal of Clinical Investigation, February 2012, Wiley

    Dr Jakob Triebel

  58. Melanocortin receptors in rat liver cells: change of gene expression and intracellular localization during acute-phase response

    Article • Histochemistry and Cell Biology, December 2011, Springer Science + Business Media

    Dr Jakob Triebel

  59. Prolactin and vasoinhibins: Endogenous players in diabetic retinopathy

    Article • IUBMB Life, September 2011, Wiley

    Dr Jakob Triebel, Carmen Clapp

  60. Investigation of prolactin-related vasoinhibin in sera from patients with diabetic retinopathy

    Article • May 2009

    Dr Jakob Triebel

  61. Nodal Dissection for Gastric Cancer

    Article • The New England Journal of Medicine and Surgery and the Collateral Branches of Science, November 2008, New England Journal of Medicine (NEJM/MMS)

    Dr Jakob Triebel