All Stories

  1. Impaired prolactin actions mediate altered offspring metabolism induced by maternal high-fat feeding during lactation

    Article • The FASEB Journal, June 2018, Federation of American Societies For Experimental Biology (FASEB)

    Carmen Clapp, Gonzalo Martinez de la Escalera, Yazmin Macotela

  2. Prolactin regulates liver growth during postnatal development in mice

    Article • AJP Regulatory Integrative and Comparative Physiology, June 2018, American Physiological Society

    Carmen Clapp

  3. Basis and Design of a Randomized Clinical Trial to Evaluate the Effect of Levosulpiride on Retinal Alterations in Patients With Diabetic Retinopathy and Diabetic Macular Edema

    Article • Frontiers in Endocrinology, May 2018, Frontiers

    Carmen Clapp, Dr Jakob Triebel

  4. From Bench to Bedside: Translating the Prolactin/Vasoinhibin Axis

    Article • Frontiers in Endocrinology, December 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  5. Human Prolactin Point Mutations and Their Projected Effect on Vasoinhibin Generation and Vasoinhibin-Related Diseases

    Article • Frontiers in Endocrinology, November 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  6. Dual contribution of TRPV4 antagonism in the regulatory effect of vasoinhibins on blood-retinal barrier permeability: diabetic milieu makes a difference

    Article • Scientific Reports, October 2017, Springer Science + Business Media

    Carmen Clapp

  7. Vasoinhibins May Contribute to Postpartum Depression

    Article • Frontiers in Psychiatry, September 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  8. Vasoinhibin Suppresses the Neurotrophic Effects of VEGF and NGF in Newborn Rat Primary Sensory Neurons

    Article • Neuroendocrinology, June 2017, Karger Publishers

    Carmen Clapp

  9. Commentary: Prolactin Alters Blood Pressure by Modulating the Activity of Endothelial Nitric Oxide Synthase

    Article • Frontiers in Endocrinology, May 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  10. Prolactin blocks the expression of receptor activator of nuclear factor κB ligand and reduces osteoclastogenesis and bone loss in murine inflammatory arthritis

    Article • May 2017, Springer Science + Business Media

    Carmen Clapp

  11. Remarks on the Prolactin Hypothesis of Peripartum Cardiomyopathy

    Article • Frontiers in Endocrinology, April 2017, Frontiers

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  12. Chapter 14. From Reproductive Neuroendocrinology and Lactation to Vasoinhibins and Angiogenesis

    Article • March 2017, Taylor & Francis

    Carmen Clapp, Gonzalo Martinez de la Escalera

  13. Vasoinhibin Serum Levels Are Required to Demonstrate Their Role in Peripartum Cardiomyopathy Etiopathology

    Article • ASAIO Journal, January 2017, Wolters Kluwer Health

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  14. Comment On: Peripartum Cardiomyopathy Treatment with Dopamine Agonist and Subsequent Pregnancy with a Satisfactory Outcome

    Article • Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, November 2016, Thieme Publishing Group

    Dr Jakob Triebel, Carmen Clapp

  15. Higher prolactin and vasoinhibin serum levels associated with incidence and progression of retinopathy of prematurity

    Article • Pediatric Research, November 2016, Springer Science + Business Media

    Dr Jakob Triebel, Carmen Clapp

  16. Prolactin Promotes Adipose Tissue Fitness and Insulin Sensitivity in Obese Males

    Article • Endocrinology, November 2016, Endocrine Society

    Carmen Clapp, Gonzalo Martinez de la Escalera, Yazmin Macotela

  17. The vasoinhibin solution structure appears unfolded, dynamic, and features aggregation

    Article • Endocrine Abstracts, May 2016, Bioscientifica

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  18. Serum proteases do not cleave prolactin to vasoinhibins at physiological pH

    Article • Endocrine Abstracts, May 2016, Bioscientifica

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  19. The role of the prolactin/vasoinhibin axis in rheumatoid arthritis: an integrative overview

    Article • Cellular and Molecular Life Sciences, March 2016, Springer Science + Business Media

    Carmen Clapp

  20. Diabetes enhances the efficacy of AAV2 vectors in the retina: therapeutic effect of AAV2 encoding vasoinhibin and soluble VEGF receptor 1

    Article • Laboratory Investigation, November 2015, Springer Science + Business Media

    Carmen Clapp

  21. Principles of the prolactin/vasoinhibin axis

    Article • AJP Regulatory Integrative and Comparative Physiology, November 2015, American Physiological Society

    Dr Jakob Triebel, Carmen Clapp

  22. Prolactin anterior pituitary expression and circulating levels are reduced in obese and diabetic rats: role of TGF-β and TNF-α

    Article • AJP Regulatory Integrative and Comparative Physiology, May 2015, American Physiological Society

    Dr. Isabel Méndez, Carmen Clapp

  23. On the Path toward Classifying Hormones of the Vasoinhibin-Family

    Article • Frontiers in Endocrinology, February 2015, Frontiers

    Dr Jakob Triebel, Carmen Clapp

  24. High Prolactin Excretion in Patients with Diabetes Mellitus and Impaired Renal Function

    Article • Clinical Laboratory, January 2015, Clinical Laboratory Publications

    Dr Jakob Triebel, Carmen Clapp

  25. Regulation of Blood Vessels by Prolactin and Vasoinhibins

    Article • December 2014, Springer Science + Business Media

    Dr Jakob Triebel, Carmen Clapp

  26. Vasoinhibins regulate the inner and outer blood-retinal barrier and limit retinal oxidative stress

    Article • Frontiers in Cellular Neuroscience, October 2014, Frontiers

    Carmen Clapp

  27. Arthritis and prolactin: A phylogenetic viewpoint

    Article • General and Comparative Endocrinology, July 2014, Elsevier

    Carmen Clapp

  28. Prolactin-derived vasoinhibins increase anxiety- and depression-related behaviors

    Article • Psychoneuroendocrinology, June 2014, Elsevier

    Dr. Isabel Méndez, Carmen Clapp

  29. Vasoinhibins are natural inhibitors of angiogenesis in the vitreous and are impaired in patients with diabetic retinopathy

    Article • Endocrine Abstracts, April 2014, Bioscientifica

    Dr Jakob Triebel, Carmen Clapp, Gonzalo Martinez de la Escalera

  30. Prolactin administration during early postnatal life decreases hippocampal and olfactory bulb neurogenesis and results in depressive-like behavior in adulthood

    Article • Hormones and Behavior, November 2013, Elsevier

    Carmen Clapp

  31. Prolactin promotes normal liver growth, survival, and regeneration in rodents: effects on hepatic IL-6, suppressor of cytokine signaling-3, and angiogenesis

    Article • AJP Regulatory Integrative and Comparative Physiology, October 2013, American Physiological Society

    Dr Jakob Triebel, Carmen Clapp

  32. Prolactin promotes cartilage survival and attenuates inflammation in inflammatory arthritis

    Article • Journal of Clinical Investigation, August 2013, American Society for Clinical Investigation

    Dr Jakob Triebel, Dr. Isabel Méndez, Carmen Clapp

  33. Requirement of phosphorylatable endothelial nitric oxide synthase at Ser-1177 for vasoinhibin-mediated inhibition of endothelial cell migration and proliferation in vitro

    Article • Endocrine, May 2013, Springer Science + Business Media

    Carmen Clapp

  34. Prolactin and blood vessels: A comparative endocrinology perspective

    Article • General and Comparative Endocrinology, May 2012, Elsevier

    Carmen Clapp, Gonzalo Martinez de la Escalera

  35. Vasoinhibin Gene Transfer by Adenoassociated Virus Type 2 Protects against VEGF- and Diabetes-Induced Retinal Vasopermeability

    Article • Investigative Opthalmology & Visual Science, November 2011, Association for Research in Vision and Ophthalmology (ARVO)

    Carmen Clapp

  36. Prolactin and vasoinhibins: Endogenous players in diabetic retinopathy

    Article • IUBMB Life, September 2011, Wiley

    Dr Jakob Triebel, Carmen Clapp

  37. Peripheral regulation of prolactin by oxytocin: focus on “Systemic oxytocin induces a prolactin secretory rhythm via the pelvic nerve in ovariectomized rats”

    Article • AJP Regulatory Integrative and Comparative Physiology, September 2011, American Physiological Society

    Carmen Clapp

  38. Vasoinhibins Prevent Bradykinin-Stimulated Endothelial Cell Proliferation by Inactivating eNOS via Reduction of both Intracellular Ca2+ Levels and eNOS Phosphorylation at Ser1179

    Article • Pharmaceuticals, July 2011, MDPI AG

    Carmen Clapp

  39. N-Terminal Prolactin-Derived Fragments, Vasoinhibins, Are Proapoptoptic and Antiproliferative in the Anterior Pituitary

    Article • PLoS ONE, July 2011, PLOS

    Carmen Clapp

  40. Prolactin Promotes Liver Regeneration after Partial Hepatectomy

    Article • June 2011, Endocrine Society

    Carmen Clapp

  41. Prolactin promotes oxytocin and vasopressin release by activating neuronal nitric oxide synthase in the supraoptic and paraventricular nuclei

    Article • AJP Regulatory Integrative and Comparative Physiology, December 2010, American Physiological Society

    Dr. Isabel Méndez, Carmen Clapp

  42. High Levels of Serum Prolactin Protect Against Diabetic Retinopathy by Increasing Ocular Vasoinhibins

    Article • Diabetes, September 2010, American Diabetes Association

    Carmen Clapp

  43. Intraocular and systemic levels of vascular endothelial growth factor in advanced cases of retinopathy of prematurity

    Article • Clinical Ophthalmology, August 2010, Taylor & Francis

    Carmen Clapp, Dr. Gerardo Garcia-Aguirre

  44. Prolactin and Vasoinhibins Exert Opposite Effects on Chondrocyte Survival.

    Article • June 2010, Endocrine Society

    Carmen Clapp, Dr. Isabel Méndez

  45. Vasoinhibins and the Pituitary Gland

    Article • January 2010, Karger Publishers

    Dr. Isabel Méndez, Carmen Clapp

  46. Prolactin in Ovarian Follicular Fluid Stimulates Endothelial Cell Proliferation

    Article • Journal of Vascular Research, January 2010, Karger Publishers

    Carmen Clapp

  47. Cathepsin D Is the Primary Protease for the Generation of Adenohypophyseal Vasoinhibins: Cleavage Occurs within the Prolactin Secretory Granules

    Article • Endocrinology, December 2009, Endocrine Society

    Carmen Clapp

  48. Peptide Hormone Regulation of Angiogenesis

    Article • Physiological Reviews, October 2009, American Physiological Society

    Carmen Clapp, Gonzalo Martinez de la Escalera

  49. Effects of prolactin deficiency during the early postnatal period on the development of maternal behavior in female rats: Mother's milk makes the difference

    Article • Hormones and Behavior, September 2009, Elsevier

    Carmen Clapp

  50. Effects of prolactin and vasoinhibins on nitric oxide synthase activity in coronary endothelial cells and vessels in isolated perfused guinea pig hearts

    Article • Toxicology Letters, October 2008, Elsevier

    Rafael Rubio, Carmen Clapp

  51. Vasoinhibins: novel inhibitors of ocular angiogenesis

    Article • AJP Endocrinology and Metabolism, October 2008, American Physiological Society

    Carmen Clapp

  52. Vasoinhibins prevent retinal vasopermeability associated with diabetic retinopathy in rats via protein phosphatase 2A–dependent eNOS inactivation

    Article • Journal of Clinical Investigation, May 2008, American Society for Clinical Investigation

    Carmen Clapp

  53. Expression and cellular localization of prolactin and the prolactin receptor in mammalian retina

    Article • Experimental Eye Research, February 2008, Elsevier

    Carmen Clapp

  54. Role of Prolactin and Vasoinhibins in the Regulation of Vascular Function in Mammary Gland

    Article • Journal of Mammary Gland Biology and Neoplasia, January 2008, Springer Science + Business Media

    Carmen Clapp

  55. Hormones and postpartum cardiomyopathy

    Article • Trends in Endocrinology and Metabolism, November 2007, Elsevier

    Carmen Clapp

  56. Elevated vasoinhibins may contribute to endothelial cell dysfunction and low birth weight in preeclampsia

    Article • Laboratory Investigation, August 2007, Springer Science + Business Media

    Carmen Clapp

  57. Prolactin-like hormone in the nematode Trichinella spiralis larvae

    Article • Experimental Parasitology, June 2007, Elsevier

    Carmen Clapp

  58. In vivo transcriptional targeting into the retinal vasculature using recombinant baculovirus carrying the human flt-1 promoter

    Article • Virology Journal, January 2007, Springer Science + Business Media

    Carmen Clapp

  59. 17-Beta-Estradiol Directly Regulates the Expression of Adrenergic Receptors and Kisspeptin/GPR54 System in GT1-7 GnRH Neurons

    Article • Neuroendocrinology, January 2007, Karger Publishers

    Carmen Clapp

  60. GABA Inhibition of Cyclic AMP Production in Immortalized GnRH Neurons Is Mediated by Calcineurin-Dependent Dephosphorylation of Adenylyl Cyclase 9

    Article • Neuroendocrinology, January 2007, Karger Publishers

    Carmen Clapp

  61. Vasoinhibins: endogenous regulators of angiogenesis and vascular function

    Article • Trends in Endocrinology and Metabolism, October 2006, Elsevier

    Carmen Clapp, Gonzalo Martinez de la Escalera

  62. Aquaporin-1: a novel promoter of tumor angiogenesis

    Article • Trends in Endocrinology and Metabolism, January 2006, Elsevier

    Carmen Clapp

  63. Vasoinhibins: A Family of N-Terminal Prolactin Fragments that Inhibit Angiogenesis and Vascular Function

    Article • January 2006, Karger Publishers

    Carmen Clapp

  64. Opposite Association of Serum Prolactin and Survival in Patients with Colon and Rectal Carcinomas: Influence of Preoperative Radiotherapy

    Article • Digestive Diseases and Sciences, January 2006, Springer Science + Business Media

    Carmen Clapp

  65. Prolactins Are Natural Inhibitors of Angiogenesis in the Retina

    Article • Investigative Opthalmology & Visual Science, August 2005, Association for Research in Vision and Ophthalmology (ARVO)

    Carmen Clapp

  66. Prolactin stimulates integrin-mediated adhesion of circulating mononuclear cells to endothelial cells

    Article • Laboratory Investigation, March 2005, Springer Science + Business Media

    Carmen Clapp

  67. 16K-Prolactin Inhibits Activation of Endothelial Nitric Oxide Synthase, Intracellular Calcium Mobilization, and Endothelium-Dependent Vasorelaxation

    Article • Endocrinology, December 2004, Endocrine Society

    Carmen Clapp

  68. Cathepsin D Processes Human Prolactin into Multiple 16K-Like N-Terminal Fragments: Study of Their Antiangiogenic Properties and Physiological Relevance

    Article • Molecular Endocrinology, October 2004, Endocrine Society

    Carmen Clapp

  69. Prolactin in Eyes of Patients with Retinopathy of Prematurity: Implications for Vascular Regression

    Article • Investigative Opthalmology & Visual Science, July 2004, Association for Research in Vision and Ophthalmology (ARVO)

    Carmen Clapp

  70. In vivo release and gene upregulation of brain prolactin in response to physiological stimuli

    Article • European Journal of Neuroscience, March 2004, Wiley

    Carmen Clapp

  71. Hypoxia Inhibits Expression of Prolactin and Secretion of Cathepsin-D by the GH4C1 Pituitary Adenoma Cell Line

    Article • Laboratory Investigation, November 2003, Springer Science + Business Media

    Carmen Clapp

  72. Cytokine induction of prolactin receptors mediates prolactin inhibition of nitric oxide synthesis in pulmonary fibroblasts

    Article • FEBS Letters, May 2003, Wiley

    Carmen Clapp

  73. Expression and purification of the angiogenesis inhibitor 16-kDa prolactin fragment from insect cells

    Article • Protein Expression and Purification, April 2003, Elsevier

    Carmen Clapp

  74. Prolactin and 16K Prolactin Stimulate Release of Vasopressin by a Direct Effect on Hypothalamo-Neurohypophyseal System

    Article • Endocrine, January 2003, Springer Science + Business Media

    Carmen Clapp

  75. Increased hypothalamic expression of prolactin in lactation: involvement in behavioural and neuroendocrine stress responses

    Article • European Journal of Neuroscience, April 2002, Wiley

    Carmen Clapp

  76. Regulation of Gonadotropin-Releasing Hormone Secretion

    Article • Archives of Medical Research, November 2001, Elsevier

    Carmen Clapp

  77. GABA Inhibition of Immortalized Gonadotropin-Releasing Hormone Neuronal Excitability Involves GABAA

    Article • Endocrine, January 2001, Springer Science + Business Media

    Carmen Clapp

  78. Molecular heterogeneity of prolactin in the plasma of patients with systemic lupus erythematosus

    Article • Arthritis & Rheumatism, January 2001, Wiley

    Carmen Clapp

  79. Proteolytic Cleavage Confers Nitric Oxide Synthase Inducing Activity upon Prolactin

    Article • Journal of Biological Chemistry, April 2000, American Society for Biochemistry & Molecular Biology (ASBMB)

    Carmen Clapp

  80. Functional uncoupling between intracellular calcium dynamics and secretion in the αT3‐1 gonadotropic cell line

    Article • Journal of Cellular Physiology, June 1999, Wiley

    Carmen Clapp

  81. Functional uncoupling between intracellular calcium dynamics and secretion in the ?T3-1 gonadotropic cell line

    Article • Journal of Cellular Physiology, June 1999, Wiley

    Carmen Clapp

  82. Potentiation of Prolactin Secretion following Lactotrope Escape from Dopamine Action

    Article • Neuroendocrinology, January 1999, Karger Publishers

    Carmen Clapp

  83. Potentiation of Prolactin Secretion following Lactotrope Escape from Dopamine Action

    Article • Neuroendocrinology, January 1999, Karger Publishers

    Carmen Clapp, Gonzalo Martinez de la Escalera

  84. Prolactins: Novel Regulators of Angiogenesis

    Article • Physiology, October 1997, American Physiological Society

    Carmen Clapp

  85. Differential effects of basic fibroblast growth factor, epidermal growth factor, transforming growth factor‐α, and insulin‐like growth factor‐I on a hypothalamic gonadotropin‐releasing hormone neuronal cell line

    Article • Journal of Neuroscience Research, September 1997, Wiley

    Carmen Clapp

  86. Differential effects of basic fibroblast growth factor, epidermal growth factor, transforming growth factor-?, and insulin-like growth factor-I on a hypothalamic gonadotropin-releasing hormone neuronal cell line

    Article • Journal of Neuroscience Research, September 1997, Wiley

    Carmen Clapp

  87. Immunoreactive Prolactin Forms Colocalize with Vasopressin in Neurons of the Hypothalamic Paraventricular and Supraoptic Nuclei

    Article • Neuroendocrinology, January 1997, Karger Publishers

    Carmen Clapp

  88. The catecholaminergic stimulation of gonadotropin-releasing hormone release by GT1-1 cells does not involve phosphoinositide hydrolysis

    Article • Life Sciences, March 1996, Elsevier

    Carmen Clapp

  89. A 14-kilodalton prolactin-like fragment is secreted by the hypothalamo-neurohypophyseal system of the rat.

    Article • Endocrinology, December 1995, Endocrine Society

    Carmen Clapp

  90. Immunoreactive prolactins of the neurohypophyseal system display actions characteristic of prolactin and 16K prolactin

    Article • Endocrine, August 1995, Springer Science + Business Media

    Carmen Clapp

  91. Histamine directly stimulates gonadotropin-releasing hormone secretion from GT1-1 cells via H1 receptors coupled to phosphoinositide hydrolysis.

    Article • Endocrinology, July 1995, Endocrine Society

    Carmen Clapp

  92. Changes in molecular variants during in vitro transformation and release of prolactin by the pituitary gland of the lactating rat.

    Article • Endocrinology, June 1992, Endocrine Society

    Carmen Clapp

  93. The 16K Fragment of Prolactin Specifically Inhibits Basal or Fibroblast Growth Factor Stimulated Growth of Capillary Endothelial Cells

    Article • Endocrinology, August 1991, Endocrine Society

    Carmen Clapp

  94. Age-related stimulatory and inhibitory effects of suckling regulate lactation in rabbits

    Article • Physiology & Behavior, August 1990, Elsevier

    Carmen Clapp

  95. Prolactin and propranolol prevent the suckling-induced inhibition of lactation in rabbits

    Article • Physiology & Behavior, August 1990, Elsevier

    Carmen Clapp

  96. Regulation of Prolactin Secretion by Dopamine and Thyrotropin-Releasing Hormone in Lactating Rat Adenohypophyses: Influence of Intracellular Age of the Hormone*

    Article • Endocrinology, October 1989, Endocrine Society

    Carmen Clapp

  97. Binding Studies with Intact Rat Prolactin and a 16K Fragment of the Hormone*

    Article • Endocrinology, August 1989, Endocrine Society

    Carmen Clapp

  98. Differential Effects of Thyrotropin-Releasing Hormone on in vitro Release of in vivo or in vitro Newly Synthesized and Mature Prolactin by Lactating Rat Adenohypophyses

    Article • Neuroendocrinology, January 1989, Karger Publishers

    Carmen Clapp

  99. Biological and Immunological Characterization of Cleaved and 16K Forms of Rat Prolactin*

    Article • Endocrinology, June 1988, Endocrine Society

    Carmen Clapp

  100. Analysis of the Proteolytic Cleavage of Prolactin by the Mammary Gland and Liver of the Rat: Characterization of the Cleaved and 16K Forms*

    Article • Endocrinology, December 1987, Endocrine Society

    Carmen Clapp

  101. Investigation into the role of dopamine and lysosomes in the impairment of prolactin transformation and release imposed by long periods of non-suckling in the rat

    Article • European Journal of Endocrinology, March 1987, Bioscientifica

    Carmen Clapp

  102. Thiol Regulation of Depletion-Transformation and Release of Prolactin by the Pituitary of the Lactating Rat*

    Article • Endocrinology, May 1986, Endocrine Society

    Carmen Clapp

  103. Reversal by Thiols of Dopamine-, Stalk-Median Eminence-, and Zinc-Induced Inhibition of Prolactin Transformation in Adenohypophyses of Lactating Rats*

    Article • Endocrinology, May 1986, Endocrine Society

    Carmen Clapp

  104. Release of Catecholamines Follows Suckling or Electrical Stimulation of Mammary Nerve in Lactating Rats*

    Article • Endocrinology, December 1985, Endocrine Society

    Carmen Clapp

  105. In-vivo and in-vitro secretion of prolactin by lactating rat adenohypophyses as a function of intracellular age

    Article • Journal of Endocrinology, April 1984, Bioscientifica

    Carmen Clapp

  106. REGULATORY AND CONTROL MECHANISMS OF PROLACTIN SECRETION WITHIN THE PITUITARY OF THE LACTATING RAT

    Article • January 1984, Elsevier

    Carmen Clapp

  107. A Solubility Shift Occurs during Depletion-Transformation of Prolactin within the Lactating Rat Pituitary*

    Article • Endocrinology, October 1982, Endocrine Society

    Carmen Clapp

  108. Latency and duration of the effects of bromocriptine and prolactin on milk secretion in lactating rabbits

    Article • Journal of Endocrinology, September 1982, Bioscientifica

    Carmen Clapp

  109. Effect of Acute Increases in Suckling Frequency upon Food Intake and Milk Secretion in the Rabbit

    Article • Experimental Biology and Medicine, December 1981, SAGE Publications

    Carmen Clapp