All Stories

  1. Differential Regulation of Inflammatory and Pro-Resolving Lipid Mediators in Chronic Coronary Syndrome Across Cardiometabolic Phenotypes

    Article • International Journal of Molecular Sciences, July 2026, MDPI AG

    Dr Giuseppe M Raffa

  2. Pulsatility as a Potential Regulator of Cardiovascular Biology: Molecular, Cellular, and Hemodynamic Remodeling During Continuous-Flow Left Ventricular Assist Device Support and Following Heart Transplantation

    Article • International Journal of Molecular Sciences, July 2026, MDPI AG

    Dr Giuseppe M Raffa

  3. Heart Failure with Reduced and Mildly Reduced Ejection Fraction: A Network Interpretive Framework of Mechanisms, Phenotypes, and Therapeutic Response

    Article • International Journal of Molecular Sciences, July 2026, MDPI AG

    Dr Giuseppe M Raffa

  4. Istaroxime in Acute Heart Failure and Early Cardiogenic Shock: A Calcium-Cycling Approach to Inotropic Therapy

    Article • International Journal of Molecular Sciences, June 2026, MDPI AG

    Dr Giuseppe M Raffa

  5. Vericiguat in the Post-Stabilization Phase of HFrEF: Targeting Residual Risk Across the Ischemia–Decompensation Continuum

    Article • International Journal of Molecular Sciences, June 2026, MDPI AG

    Dr Giuseppe M Raffa

  6. Outcomes of Transcatheter Aortic Valve Implantation with Abbott’s Portico Compared to Edwards’ SAPIEN 3: A Systematic Review and Meta-Analysis

    Article • Journal of Clinical Medicine, May 2026, MDPI AG

    Dr Giuseppe M Raffa

  7. The Quantitative Haemodynamic Effect of Levosimendan, Dobutamine and Milrinone in Heart Failure Patients: a Meta-Analysis

    Article • ESC Heart Failure, April 2026, Oxford University Press (OUP)

    Dr Giuseppe M Raffa

  8. Valve-in-Valve Transcatheter Aortic Valve Implantation Versus Redo SAVR for Degenerated Biological Prosthesis: A Narrative Review Stating Our Experience

    Article • Journal of Clinical Medicine, October 2025, MDPI AG

    Dr Giuseppe M Raffa

  9. Biomarkers in Heart Failure: A Review and a Wish

    Article • International Journal of Molecular Sciences, August 2025, MDPI AG

    Dr Giuseppe M Raffa, Prof Carmela Rita Balistreri

  10. When Real-World Outcomes Do Not Meet the Results of Clinical Trials: Transfemoral Transcatheter vs. Surgical Aortic Valve Replacement in an Intermediate-Age Population (The Outstanding Italy Study)

    Article • Journal of Clinical Medicine, May 2025, MDPI AG

    Dr Giuseppe M Raffa

  11. Review of Contemporary Invasive Treatment Approaches and Critical Appraisal of Guidelines on Hypertrophic Obstructive Cardiomyopathy: State-of-the-Art Review

    Article • Journal of Clinical Medicine, June 2022, MDPI AG

    Dr Giuseppe M Raffa

  12. Atlas-Based Evaluation of Hemodynamic in Ascending Thoracic Aortic Aneurysms

    Article • Applied Sciences, December 2021, MDPI AG

    Dr Giuseppe M Raffa

  13. Patient-Specific Analysis of Ascending Thoracic Aortic Aneurysm with the Living Heart Human Model

    Article • Bioengineering, November 2021, MDPI AG

    Dr Giuseppe M Raffa

  14. Defining and understanding the “extra‐corporeal membrane oxygenation gap” in the veno‐venous configuration: Timing and causes of death

    Article • Artificial Organs, September 2021, Wiley

    Dr Giuseppe M Raffa

  15. miRNA expression analysis in the human heart: Undifferentiated progenitors vs. bioptic tissues—Implications for proliferation and ageing

    Article • Journal of Cellular and Molecular Medicine, August 2021, Wiley

    Dr Giuseppe M Raffa

  16. Understanding the “extracorporeal membrane oxygenation gap” in veno‐arterial configuration for adult patients: Timing and causes of death

    Article • Artificial Organs, July 2021, Wiley

    Dr Giuseppe M Raffa

  17. Transcatheter Heart Valve Implantation in Bicuspid Patients with Self-Expanding Device

    Article • Bioengineering, July 2021, MDPI AG

    Dr Giuseppe M Raffa

  18. ECMO Retrieval over the Mediterranean Sea: Extending Hospital Arms

    Article • Membranes, March 2021, MDPI AG

    Dr Giuseppe M Raffa

  19. 2020 EACTS/ELSO/STS/AATS Expert Consensus on Post-cardiotomy Extracorporeal Life Support in Adult Patients

    Article • ASAIO Journal, December 2020, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  20. Ascending Aorta Resection and End-to-End Anastomosis: Redistribution of Wall Shear Stress Induced by a Bioprosthetic Heart Valve

    Article • Prosthesis, October 2020, MDPI AG

    Dr Giuseppe M Raffa

  21. 2020 EACTS/ELSO/STS/AATS expert consensus on post-cardiotomy extracorporeal life support in adult patients

    Article • European Journal of Cardio-Thoracic Surgery, October 2020, Oxford University Press (OUP)

    Dr Giuseppe M Raffa

  22. 2020 EACTS/ELSO/STS/AATS expert consensus on post-cardiotomy extracorporeal life support in adult patients

    Article • Journal of Thoracic and Cardiovascular Surgery, October 2020, Elsevier

    Dr Giuseppe M Raffa

  23. The use of extracorporeal membrane oxygenation in the setting of postinfarction mechanical complications: outcome analysis of the Extracorporeal Life Support Organization Registry

    Article • Interactive Cardiovascular and Thoracic Surgery, July 2020, Oxford University Press (OUP)

    Dr Giuseppe M Raffa

  24. Extracorporeal life support for phaeochromocytoma-induced cardiogenic shock: a systematic review

    Article • Perfusion, May 2020, SAGE Publications

    Dr Giuseppe M Raffa

  25. Statistical Shape Analysis of Ascending Thoracic Aortic Aneurysm: Correlation between Shape and Biomechanical Descriptors

    Article • Journal of Personalized Medicine, April 2020, MDPI AG

    Dr Giuseppe M Raffa

  26. Transcatheter Aortic Valve Replacement with Self-Expandable ACURATE neo as compared to Balloon-Expandable SAPIEN 3 in Patients with Severe Aortic Stenosis: Meta-analysis of Randomized and Propensity-Matched Studies. J. Clin. Med. 2020, 9, 397

    Article • Journal of Clinical Medicine, March 2020, MDPI AG

    Dr Giuseppe M Raffa

  27. Pulmonary artery cannulation to enhance extracorporeal membrane oxygenation management in acute cardiac failure

    Article • Interactive Cardiovascular and Thoracic Surgery, October 2019, Oxford University Press (OUP)

    Dr Giuseppe M Raffa

  28. Baseline surgical status and short-term mortality after extracorporeal membrane oxygenation for post-cardiotomy shock: a meta-analysis

    Article • Perfusion, August 2019, SAGE Publications

    Dr Giuseppe M Raffa

  29. Neurological complications after cardiac surgery: a retrospective case-control study of risk factors and outcome

    Article • Journal of Cardiothoracic Surgery, January 2019, Springer Science + Business Media

    Dr Giuseppe M Raffa

  30. In-hospital outcomes after emergency or prophylactic veno-arterial extracorporeal membrane oxygenation during transcatheter aortic valve implantation: a comprehensive review of the literature

    Article • Perfusion, January 2019, SAGE Publications

    Dr Giuseppe M Raffa

  31. Protracted aortic valve closure during peripheral veno-arterial extracorporeal life support: is intra-aortic balloon pump an effective solution?

    Article • Perfusion, July 2018, SAGE Publications

    Dr Giuseppe M Raffa

  32. PATHOANATOMIC FINDINGS AND TREATMENT DURING HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY SURGERY: THE ROLE OF MITRAL VALVE

    Article • Heart Lung and Circulation, February 2018, Elsevier

    Dr Giuseppe M Raffa

  33. Heart valve scaffold fabrication: Bioinspired control of macro-scale morphology, mechanics and micro-structure

    Article • Biomaterials, January 2018, Elsevier

    Dr Giuseppe M Raffa

  34. How do I get my article published? Insight from an EACTS luncheon

    Article • Journal of Cardiovascular Medicine, October 2017, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  35. Acute Obstructive Thrombosis of Sapien 3 Valve After Valve-in-Valve Transcatheter Aortic Valve Replacement for Degenerated Mosaic 21 Valve

    Article • JACC Cardiovascular Interventions, October 2017, Elsevier

    Dr Giuseppe M Raffa

  36. Meta-analysis to assess the effectiveness of topically used vancomycin in reducing sternal wound infections after cardiac surgery

    Article • Journal of Thoracic and Cardiovascular Surgery, October 2017, Elsevier

    Dr Giuseppe M Raffa

  37. In Vivo Strain Analysis of Dilated Ascending Thoracic Aorta by ECG-Gated CT Angiographic Imaging

    Article • Annals of Biomedical Engineering, September 2017, Springer Science + Business Media

    Dr Giuseppe M Raffa

  38. Impact of Sternotomy and Pericardial Opening in Patients With Ventricular Septal Defects

    Article • Anesthesia & Analgesia, September 2017, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  39. Particle image velocimetry study of the celiac trunk hemodynamic induced by continuous-flow left ventricular assist device

    Article • Medical Engineering & Physics, September 2017, Elsevier

    Dr Giuseppe M Raffa

  40. In Silico Shear and Intramural Stresses are Linked to Aortic Valve Morphology in Dilated Ascending Aorta

    Article • European Journal of Vascular and Endovascular Surgery, August 2017, Elsevier

    Dr Giuseppe M Raffa

  41. Critical care for migrants

    Article • Intensive Care Medicine, May 2017, Springer Science + Business Media

    Dr Giuseppe M Raffa

  42. Should subcutaneous implantable cardioverter-defibrillators be implanted in patients who are candidates for continuous flow left ventricular assist device?

    Article • European Journal of Internal Medicine, May 2017, Elsevier

    Dr Giuseppe M Raffa

  43. Modalities and Effects of Left Ventricle Unloading on Extracorporeal Life support: a Review of the Current Literature

    Article • European Journal of Heart Failure, May 2017, Wiley

    Dr Yuri Ganushchak, Dr Giuseppe M Raffa, Dr Daniel Johnson

  44. Antihypertensive Treatments in Patients Affected by Aortic Valve Stenosis

    Article • Current Pharmaceutical Design, April 2017, Bentham Science Publishers

    Dr Giuseppe M Raffa

  45. Migrants crossing the Mediterranean Sea: an opportunity or a duty?

    Article • Intensive Care Medicine, March 2017, Springer Science + Business Media

    Dr Giuseppe M Raffa

  46. Three-dimensional parametric modeling of bicuspid aortopathy and comparison with computational flow predictions

    Article • Artificial Organs, February 2017, Wiley

    Dr Giuseppe M Raffa

  47. Training in Coronary Artery Bypass Surgery: Tips and Tricks of the Trade

    Article • Seminars in Thoracic and Cardiovascular Surgery, February 2017, Elsevier

    Dr Giuseppe M Raffa

  48. A Case of Conservative Treatment of Postsurgical Aortic False Aneurysm

    Article • International Cardiovascular Forum Journal, January 2017, International Cardiovascular Forum Journal

    Dr Giuseppe M Raffa

  49. Risk of stroke with “no-touch” — As compared to conventional off-pump coronary artery bypass grafting. An updated meta-analysis of observational studies

    Article • International Journal of Cardiology, November 2016, Elsevier

    Dr Giuseppe M Raffa

  50. Meta-analysis of uninterrupted as compared to interrupted oral anticoagulation with or without bridging in patients undergoing coronary angiography with or without percutaneous coronary intervention

    Article • International Journal of Cardiology, November 2016, Elsevier

    Dr Giuseppe M Raffa

  51. Clinical Safety and Effectiveness of Endoaortic as Compared to Transthoracic Clamp for Small Thoracotomy Mitral Valve Surgery: Meta-Analysis of Observational Studies

    Article • The Annals of Thoracic Surgery, October 2016, Elsevier

    Dr Giuseppe M Raffa

  52. Computational fluid dynamics of the ascending aorta before the onset of type A aortic dissection

    Article • European Journal of Cardio-Thoracic Surgery, September 2016, Oxford University Press (OUP)

    Dr Giuseppe M Raffa

  53. From Small Coronary Artery Aneurysm to Giant Left Ventricle Aneurysm

    Article • Medical Principles and Practice, September 2016, Karger Publishers

    Dr Giuseppe M Raffa

  54. Heart transplant program at IRCCS-ISMETT: Impact of mechanical circulatory support on pre- and post -transplant survival

    Article • International Journal of Cardiology, September 2016, Elsevier

    Dr Giuseppe M Raffa

  55. Early distal remodeling after elephant trunk repair of thoraco-abdominal aortic aneurysms

    Article • Journal of Biomechanics, August 2016, Elsevier

    Dr Giuseppe M Raffa

  56. PIWI-interacting RNA (piRNA) signatures in human cardiac progenitor cells

    Article • The International Journal of Biochemistry & Cell Biology, July 2016, Elsevier

    Dr Giuseppe M Raffa

  57. Aortic surgery in Marfan patient with severe pectus excavatum

    Article • Journal of Cardiovascular Medicine, June 2016, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  58. International Participation in The Society of Thoracic Surgeons Database Improves Outcomes: Initial Italian Experience

    Article • The Annals of Thoracic Surgery, May 2016, Elsevier

    Dr Giuseppe M Raffa

  59. Can multiple previous treatment-requiring rejections affect biventricular myocardial function in heart transplant recipients? A two-dimensional speckle-tracking study

    Article • International Journal of Cardiology, April 2016, Elsevier

    Dr Giuseppe M Raffa

  60. Patients with bicuspid aortic valve are likely to receive an aortic valve prosthesis during prophylactic resection of their ascending aortic aneurysm

    Article • International Journal of Cardiology, March 2016, Elsevier

    Dr Giuseppe M Raffa

  61. Constitutive modeling of ascending thoracic aortic aneurysms using microstructural parameters

    Article • Medical Engineering & Physics, February 2016, Elsevier

    Dr Giuseppe M Raffa

  62. Cerebrovascular Events After No‐Touch Off‐Pump Coronary Artery Bypass Grafting, Conventional Side‐Clamp Off‐Pump Coronary Artery Bypass, and Proximal Anastomotic Devices: A Meta‐Analysis

    Article • Journal of the American Heart Association, February 2016, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  63. Your Results, Explained: Clarity Provided by Row Percentages Versus Column Percentages

    Article • The Annals of Thoracic Surgery, January 2016, Elsevier

    Dr Giuseppe M Raffa

  64. Off-pump coronary artery bypass grafting improves short-term outcomes in high-risk patients compared with on-pump coronary artery bypass grafting: Meta-analysis

    Article • Journal of Thoracic and Cardiovascular Surgery, January 2016, Elsevier

    Dr Giuseppe M Raffa

  65. Robotic mitral repair with sliding leaflet valvuloplasty and remodelling partial annuloplasty

    Article • Multimedia Manual of Cardio-Thoracic Surgery, January 2016, Oxford University Press (OUP)

    Dr Giuseppe M Raffa

  66. Safety and efficacy of miniaturized extracorporeal circulation when compared with off-pump and conventional coronary artery bypass grafting: evidence synthesis from a comprehensive Bayesian-framework network meta-analysis of 134 randomized controlled t...

    Article • European Journal of Cardio-Thoracic Surgery, November 2015, Oxford University Press (OUP)

    Dr Giuseppe M Raffa

  67. Biomechanical implications of excessive endograft protrusion into the aortic arch after thoracic endovascular repair

    Article • Computers in Biology and Medicine, November 2015, Elsevier

    Dr Giuseppe M Raffa

  68. Stanford Type A Acute Retrograde Aortic Dissections: From Surgical to Endovascular Strategy?

    Article • Artificial Organs, October 2015, Wiley

    Dr Giuseppe M Raffa

  69. An In Vitro Phantom Study on the Role of the Bird-Beak Configuration in Endograft Infolding in the Aortic Arch

    Article • Journal of Endovascular Therapy, October 2015, SAGE Publications

    Dr Giuseppe M Raffa

  70. Recurrent ventricular tachycardia in a patient with continuous flow left ventricle assist device: Successful management with radiofrequency ablation and medical treatment

    Article • International Journal of Cardiology, July 2015, Elsevier

    Dr Giuseppe M Raffa

  71. Cusp repair during aortic valve-sparing operation

    Article • Journal of Cardiovascular Medicine, April 2015, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  72. Systemic or Endoventricular Thrombolysis to Treat HeartWare Left Ventricle Assist Device Thrombosis: A Clinical Dilemma

    Article • Artificial Organs, March 2015, Wiley

    Dr Giuseppe M Raffa

  73. Minimally invasive direct coronary artery bypass in the era of percutaneous coronary intervention

    Article • Journal of Cardiovascular Medicine, February 2015, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  74. Thalassemia and Heart Surgery: Aortic Valve Repair After Endocarditis

    Article • The Annals of Thoracic Surgery, January 2015, Elsevier

    Dr Giuseppe M Raffa

  75. Should device replacement be the first choice strategy in continuous-flow left ventricle assist device thrombosis? Analysis of 9 events and results after endoventricular thrombolysis

    Article • International Journal of Cardiology, January 2015, Elsevier

    Dr Giuseppe M Raffa

  76. Should Pectus Excavatum Alter Aortic Root Surgery in Patients With Marfan Syndrome? A Computed Tomography Scan–Guided Surgical Strategy Through Left Anterior Thoracotomy

    Article • Seminars in Thoracic and Cardiovascular Surgery, January 2015, Elsevier

    Dr Giuseppe M Raffa

  77. Commentary: The Bird-Beak Stent-Graft Configuration: The End of Aortic Arch Endograft Collapse?

    Article • Journal of Endovascular Therapy, December 2014, International Society of Endovascular Specialists

    Dr Giuseppe M Raffa

  78. Chronic Stanford type A aortic dissection

    Article • Journal of Cardiovascular Medicine, August 2014, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  79. Vascular access complications in patients with continuous-flow left ventricle assist device undergoing percutaneous invasive procedures: A word of caution

    Article • International Journal of Cardiology, July 2014, Elsevier

    Dr Giuseppe M Raffa

  80. Preserving the left subclavian artery patency in challenging proximal neck during thoracic endovascular aortic repair

    Article • Journal of Cardiovascular Medicine, May 2014, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  81. Surgical treatment of systemic embolization by cardiac metastasis of lung cancer

    Article • Asian Cardiovascular and Thoracic Annals, October 2013, SAGE Publications

    Dr Giuseppe M Raffa

  82. Postsurgical aortic false aneurysm

    Article • Journal of Cardiovascular Medicine, August 2013, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  83. Hamartoma of mature cardiac myocytes: a cardiac tumour with preserved contractility

    Article • European Heart Journal - Cardiovascular Imaging, June 2013, European Society of Cardiology

    Dr Giuseppe M Raffa

  84. Conversion to Sternotomy During Sternal-Sparing Coronary Artery Surgery

    Article • Journal of Cardiac Surgery, April 2013, Wiley

    Dr Giuseppe M Raffa

  85. Sutureless repair for postinfarction cardiac rupture: A simple approach with a tissue-adhering patch

    Article • Journal of Thoracic and Cardiovascular Surgery, February 2013, Elsevier

    Dr Giuseppe M Raffa

  86. Mitral and Aortic Valve Prosthetic Endocarditis After Percutaneous Closure of Mitral Paravalvular Leak

    Article • The Annals of Thoracic Surgery, February 2013, Elsevier

    Dr Giuseppe M Raffa

  87. Hamartoma of mature cardiac myocytes in adults and young: Case report and literature review

    Article • International Journal of Cardiology, February 2013, Elsevier

    Dr Giuseppe M Raffa

  88. Left ventricular pseudoaneurysm following aortic valve prosthesis endocarditis

    Article • Journal of Cardiovascular Medicine, December 2012, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  89. Fish Oil and Postoperative Atrial Fibrillation

    Article • JAMA, November 2012, American Medical Association (AMA)

    Dr Jason Wu, Dr Giuseppe M Raffa

  90. Left ventricular cleft

    Article • European Heart Journal - Cardiovascular Imaging, July 2012, European Society of Cardiology

    Dr Giuseppe M Raffa

  91. Left ventricular pseudoaneurysm following aortic valve prosthesis endocarditis

    Article • Journal of Cardiovascular Medicine, July 2012, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  92. 6 Months of “Temporary” Support by Levitronix Left Ventricular Assist Device

    Article • Artificial Organs, March 2012, Wiley

    Dr Giuseppe M Raffa

  93. Bicuspidy does not affect reoperation risk following aortic valve reimplantation

    Article • Interactive Cardiovascular and Thoracic Surgery, March 2012, Oxford University Press (OUP)

    Dr Giuseppe M Raffa

  94. Aortic Valve Replacement for Paraprosthetic Leak After Transcatheter Implantation

    Article • Journal of Cardiac Surgery, December 2011, Wiley

    Dr Giuseppe M Raffa

  95. Giant left atrium syndrome

    Article • Journal of Cardiovascular Medicine, October 2011, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  96. Long-Term Patency of Saphenous Vein Patch Plasty for Left Main Coronary Artery Ostial Disease

    Article • Journal of Cardiac Surgery, September 2011, Wiley

    Dr Giuseppe M Raffa

  97. Incidence of Neoplastic Disease Following Lung Transplantation: A 17-Year Single-Center Experience

    Article • Transplantation Proceedings, May 2011, Elsevier

    Dr Giuseppe M Raffa

  98. Domino Heart Transplantation: Long-Term Outcome of Recipients and Their Living Donors: Single Center Experience

    Article • Transplantation Proceedings, November 2010, Elsevier

    Dr Giuseppe M Raffa

  99. Treatment of ascending aorta disease with Bentall–De Bono operation using a mini-invasive approach

    Article • Journal of Cardiovascular Medicine, October 2008, Wolters Kluwer Health

    Dr Giuseppe M Raffa

  100. Minimally Invasive Video-Assisted Surgery for Iatrogenic Aortic Root-to-Right Atrium Fistula After Incomplete Percutaneous Occlusion of Patent Foramen Ovale: Case Report and Review of the Literature

    Article • Journal of Cardiac Surgery, January 2008, Wiley

    Dr Giuseppe M Raffa