All Stories

  1. Gliclazide reduced oxidative stress, inflammation, and bone loss in an experimental periodontal disease model
  2. Metformin Hydrochloride-Loaded PLGA Nanoparticle in Periodontal Disease Experimental Model Using Diabetic Rats
  3. Protective effect of angiotensin II receptor blocker against oxidative stress and inflammation in an oral mucositis experimental model
  4. Telmisartan Modulates the Oral Mucositis Induced by 5-Fluorouracil in Hamsters
  5. Gingerol suppresses sepsis-induced acute kidney injury by modulating methylsulfonylmethane and dimethylamine production
  6. AMPK activation promotes gastroprotection through mutual interaction with the gaseous mediators H 2 S, NO, and CO
  7. Role of TRPV1 receptor in inflammation and impairment of esophageal mucosal integrity in a murine model of nonerosive reflux disease
  8. Antinociceptive, anti-inflammatory and toxicological evaluation of semi-synthetic molecules obtained from a benzyl-isothiocyanate isolated from Moringa oleifera Lam. in a temporomandibular joint inflammatory hypernociception model in rats
  9. Heme oxygenase-1/biliverdin/carbon monoxide pathway downregulates hypernociception in rats by a mechanism dependent on cGMP/ATP-sensitive K+ channels
  10. Anti-inflammatory and antiresorptive effects of Calendula officinalis on inflammatory bone loss in rats
  11. 5-Fluorouracil induces inflammation and oxidative stress in the major salivary glands affecting salivary flow and saliva composition
  12. Molecular epidemiology of Clostridium difficile infection in a Brazilian cancer hospital
  13. Inflammatory pain assessment in the arthritis of the temporomandibular joint in rats: A comparison between two phlogistic agents
  14. Apoptosis in human liver carcinoma caused by gold nanoparticles in combination with carvedilol is mediated via modulation of MAPK/Akt/mTOR pathway and EGFR/FAAD proteins
  15. Protective effect of dexamethasone on 5-FU-induced oral mucositis in hamsters
  16. Morphological characterization of ckd in cats: Insights of fibrogenesis to be recognized
  17. Study of the protective effect of dexamethasone on cisplatin-induced ototoxicity in rats
  18. Carvacryl acetate, a novel semisynthetic monoterpene ester, binds to the TRPA1 receptor and is effective in attenuating irinotecan-induced intestinal mucositis in mice
  19. Role of the route of leukotrienes in an experimental model of oral mucositis induced by 5-fluorouracil
  20. Effects of metformin on inflammation, oxidative stress, and bone loss in a rat model of periodontitis
  21. Transforming Growth Factor β1/SMAD Signaling Pathway Activation Protects the Intestinal Epithelium from Clostridium difficile Toxin A-Induced Damage
  22. Anti-inflammatory and anti-nociceptive effects of strontium ranelate on the zymosan-induced temporomandibular joint inflammatory hypernociception in rats depend on TNF-α inhibition
  23. The Effect of Calendula officinalis on Oxidative Stress and Bone Loss in Experimental Periodontitis
  24. Effects of glucocorticoid-induced osteoporosis on bone tissue of rats with experimental periodontitis
  25. The involvement of mast cells in the irinotecan-induced enteric neurons loss and reactive gliosis
  26. Physiological Targets for the Treatment of Diabetic Encephalopathy
  27. Experimental Diabetes Alters the Morphology and Nano-Structure of the Achilles Tendon
  28. Effect of Remote Ischemic Preconditioning on Systemic Toxicity and Ototoxicity Induced by Cisplatin in Rats: Role of TNF-α and Nitric Oxide
  29. Curcumin reverses neurochemical, histological and immuno-histochemical alterations in the model of global brain ischemia
  30. Sistema Digestório: Integração Básico-Clínica
  31. Side-Effects of Irinotecan (CPT-11), the Clinically Used Drug for Colon Cancer Therapy, Are Eliminated in Experimental Animals Treated with Latex Proteins fromCalotropis procera(Apocynaceae)
  32. Impact of acute undernutrition on growth, ileal morphology and nutrient transport in a murine model
  33. Effects of Atorvastatin on Periodontitis of Rats Subjected to Glucocorticoid-Induced Osteoporosis
  34. Lectin from Abelmoschus esculentus reduces zymosan-induced temporomandibular joint inflammatory hypernociception in rats via heme oxygenase-1 pathway integrity and tnf-α and il-1β suppression
  35. A MLST Clade 2 Clostridium difficile strain with a variant TcdB induces severe inflammatory and oxidative response associated with mucosal disruption
  36. Anti-inflammatory and Anti-resorptive Effects of Atorvastatin on Alveolar Bone Loss in Wistar Rats
  37. Correction: Topical HPMC/S-Nitrosoglutathione Solution Decreases Inflammation and Bone Resorption in Experimental Periodontal Disease in Rats
  38. Topical HPMC/S-Nitrosoglutathione Solution Decreases Inflammation and Bone Resorption in Experimental Periodontal Disease in Rats
  39. Wound healing modulation by a latex protein-containing polyvinyl alcohol biomembrane
  40. Carvedilol Improves Inflammatory Response, Oxidative Stress and Fibrosis in the Alcohol-Induced Liver Injury in Rats by Regulating Kuppfer Cells and Hepatic Stellate Cells
  41. Omega-3 Fatty Acids: Possible Neuroprotective Mechanisms in the Model of Global Ischemia in Rats
  42. Clinical efficacy of a 1% Matricaria chamomile L. mouthwash and 0.12% chlorhexidine for gingivitis control in patients undergoing orthodontic treatment with fixed appliances
  43. A new animal model of intestinal mucositis induced by the combination of irinotecan and 5-fluorouracil in mice
  44. Target Inhibition of IL-1 Receptor Prevents Ifosfamide Induced Hemorrhagic Cystitis in Mice
  45. Antinociceptive and anti-inflammatory effects of Caryocar coriaceum Wittm fruit pulp fixed ethyl acetate extract on zymosan-induced arthritis in rats
  46. The Adaptor Protein Myd88 Is a Key Signaling Molecule in the Pathogenesis of Irinotecan-Induced Intestinal Mucositis
  47. Gabapentin attenuates neuropathic pain and improves nerve myelination after chronic sciatic constriction in rats
  48. Effects of Kaurenoic Acid and Arginine on Random Skin Flap Oxidative Stress, Inflammation, and Cytokines in Rats
  49. Oil mixes omega 9, 6 and 3, enriched with seaweed, promoted reduction of thermal burned modulating NF-kB and Ki-67
  50. Alanyl-glutamine attenuates 5-fluorouracil-induced intestinal mucositis in apolipoprotein E-deficient mice
  51. Pentoxifylline reduces the inflammatory process in diabetic rats: relationship with decreases of pro-inflammatory cytokines and inducible nitric oxide synthase
  52. A novel model of megavoltage radiation-induced oral mucositis in hamsters: Role of inflammatory cytokines and nitric oxide
  53. Sensory and inflammatory colonic changes induced by vincristine in distinct rat models of colitis
  54. The Enteric Glia: Identity and Functions
  55. Azilsartan Reduced TNF-α and IL-1β Levels, Increased IL-10 Levels and Upregulated VEGF, FGF, KGF, and TGF-α in an Oral Mucositis Model
  56. Emergence of an Outbreak-Associated Clostridium difficile Variant with Increased Virulence
  57. Pentoxifylline Neuroprotective Effects Are Possibly Related to Its Anti-Inflammatory and TNF-Alpha Inhibitory Properties, in the 6-OHDA Model of Parkinson’s Disease
  58. The Resin fromProtium heptaphyllumPrevents High-Fat Diet-Induced Obesity in Mice: Scientific Evidence and Potential Mechanisms
  59. Olmesartan Decreased Levels of IL-1β and TNF-α, Down-Regulated MMP-2, MMP-9, COX-2, RANK/RANKL and Up-Regulated SOCs-1 in an Intestinal Mucositis Model
  60. S-Nitrosoglutathione Accelerates Recovery from 5-Fluorouracil-Induced Oral Mucositis
  61. Electroacupuncture ameliorates experimental colitis induced by TNBS through activation of interleukin-10 and inhibition of iNOS in mice
  62. Bothrops jararacussu snake venom-induces a local inflammatory response in a prostanoid- and neutrophil-dependent manner
  63. Guided bone regeneration produced by new mineralized and reticulated collagen membranes in critical-sized rat calvarial defects
  64. Community-acquired diarrhea associated with Clostridium difficile in an HIV-positive cancer patient: first case report in Latin America
  65. Chemotherapy-associated steatohepatitis induced by irinotecan: a novel animal model
  66. Azilsartan Increases Levels of IL-10, Down-Regulates MMP-2, MMP-9, RANKL/RANK, Cathepsin K and Up-Regulates OPG in an Experimental Periodontitis Model
  67. Caffeine neuroprotective effects on 6-OHDA-lesioned rats are mediated by several factors, including pro-inflammatory cytokines and histone deacetylase inhibitions
  68. Targeted inhibition of IL-18 attenuates irinotecan-induced intestinal mucositis in mice
  69. Tephrosia toxicaria Pers. reduces temporomandibular joint inflammatory hypernociception: The involvement of the HO-1 pathway
  70. Clostridium difficile Toxin A Attenuates Wnt/β-Catenin Signaling in Intestinal Epithelial Cells
  71. Infliximab attenuates inflammatory osteolysis in a model of periodontitis in Wistar rats
  72. Neuroprotective Properties of a Standardized Extract fromMyracrodruon urundeuvaFr. All. (Aroeira-Do-Sertão), as Evaluated by a Parkinson’s Disease Model in Rats
  73. Pentoxifylline decreases glycemia levels and TNF-alpha, iNOS and COX-2 expressions in diabetic rat pancreas
  74. Amitriptyline, clomipramine, and maprotiline attenuate the inflammatory response by inhibiting neutrophil migration and mast cell degranulation
  75. Oral gabapentin treatment accentuates nerve and peripheral inflammatory responses following experimental nerve constriction in Wistar rats
  76. Effect of telmisartan on levels of IL-1, TNF-α, down-regulated COX-2, MMP-2, MMP-9 and RANKL/RANK in an experimental periodontitis model
  77. Experimental Diabetes Induces Structural, Inflammatory and Vascular Changes of Achilles Tendons
  78. 1,8-cineole (eucalyptol) ameliorates cerulein-induced acute pancreatitis via modulation of cytokines, oxidative stress and NF-κB activity in mice
  79. Olmesartan decreases IL-1β and TNF-α levels; downregulates MMP-2, MMP-9, COX-2, and RANKL; and upregulates OPG in experimental periodontitis
  80. Eicosapentaenoic acid and docosahexaenoic acid exert anti-inflammatory and antinociceptive effects in rodents at low doses
  81. Valproic acid: an anticonvulsant drug with potent antinociceptive and anti-inflammatory properties
  83. Piperine decreases pilocarpine-induced convulsions by GABAergic mechanisms
  84. Glutamine and Alanyl-Glutamine Increase RhoA Expression and ReduceClostridium difficileToxin-A-Induced Intestinal Epithelial Cell Damage
  85. The Antioxidant Effects of the Flavonoids Rutin and Quercetin Inhibit Oxaliplatin-Induced Chronic Painful Peripheral Neuropathy
  86. Vitamin E does not prevent bone loss and induced anxiety in rats with ligature-induced periodontitis
  87. Protective effects of alanyl-glutamine supplementation against nelfinavir-induced epithelial impairment in IEC-6 cells and in mouse intestinal mucosa
  88. CB1 and CB2 contribute to antinociceptive and anti-inflammatory effects of electroacupuncture on experimental arthritis of the rat temporomandibular joint
  89. Antihyperglycemic and hypolipidemic effects of α, β-amyrin, a triterpenoid mixture from Protium heptaphyllum in mice
  90. Protein fraction of Calotropis procera latex protects against 5-fluorouracil-induced oral mucositis associated with downregulation of pivotal pro-inflammatory mediators
  91. Blockade of TRPA1 with HC-030031 attenuates visceral nociception by a mechanism independent of inflammatory resident cells, nitric oxide and the opioid system
  92. Effects of hecogenin and its possible mechanism of action on experimental models of gastric ulcer in mice
  93. Inflammation induced by phytomodulatory proteins from the latex of Calotropis procera (Asclepiadaceae) protects against Salmonella infection in a murine model of typhoid fever
  94. S-Nitrosoglutathione Decreases Inflammation and Bone Resorption in Experimental Periodontitis in Rats
  95. Antinociceptive and anti-inflammatory effects of electroacupuncture on experimental arthritis of the rat temporomandibular joint
  96. Changes in morphology of long bone marrow tissue of rats submitted to cryotherapy with liquid nitrogen
  97. Preconditioning with a Novel Metallopharmaceutical NO Donor in Anesthetized Rats Subjected to Brain Ischemia/Reperfusion
  98. Histomorphometric assessment of bone necrosis produced by two cryosurgery protocols using liquid nitrogen: an experimental study on rat femurs
  99. Involvement of nitric oxide on the pathogenesis of irinotecan-induced intestinal mucositis: role of cytokines on inducible nitric oxide synthase activation
  100. Pectin from Passiflora edulis Shows Anti-inflammatory Action as well as Hypoglycemic and Hypotriglyceridemic Properties in Diabetic Rats
  101. Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents
  102. Interleukin-4 Modulates the Inflammatory Response in Ifosfamide-Induced Hemorrhagic Cystitis
  103. Anti-inflammatory effect of α,β-amyrin, a triterpene from Protium heptaphyllum, on cerulein-induced acute pancreatitis in mice
  104. Role of the haem oxygenase/carbon monoxide pathway in Clostridium difficile toxin A-induced enteritis in mice
  105. Anti-inflammatory properties of Doxycycline and Minocycline in experimental models: an in vivo and in vitro comparative study
  106. In vivo and in vitro anti-inflammatory and anti-nociceptive activities of lovastatin in rodents
  107. Effect of different cryosurgical protocols using liquid nitrogen on bone tissue: a histomorphological analyze
  108. Experimental Model of Zymosan-Induced Arthritis in the Rat Temporomandibular Joint: Role of Nitric Oxide and Neutrophils
  109. Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice
  110. Adenosine Deaminase Inhibition PreventsClostridium difficileToxin A-Induced Enteritis in Mice
  111. Polyanionic collagen membranes for guided tissue regeneration: Effect of progressive glutaraldehyde cross-linking on biocompatibility and degradation
  112. Gastroprotective effect of heme-oxygenase 1/biliverdin/CO pathway in ethanol-induced gastric damage in mice
  113. Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice
  114. Topical anti-inflammatory potential of Physalin E from Physalis angulata on experimental dermatitis in mice
  115. Effect of atorvastatin on 5-fluorouracil-induced experimental oral mucositis
  116. Cyclooxygenase-2 contributes to functional changes seen on experimental hemorrhagic cystitis induced by ifosfamide in rat urinary bladder
  117. Role of Capsaicin-Sensitive Primary Afferent Neurons and Non-protein Sulphydryl Groups on Gastroprotective Effect of Amifostine Against Ethanol-Induced Gastric Damage in Rats
  118. Effect of venlafaxine on bone loss associated with ligature-induced periodontitis in Wistar rats
  119. Anti-inflammatory effects and possible mechanism of action of lupeol acetate isolated from Himatanthus drasticus (Mart.) Plumel
  120. The Natural Flavonoid Quercetin Ameliorates Cerulein-Induced Acute Pancreatitis in Mice
  121. α,β-amyrin, a natural triterpenoid ameliorates L-arginine-induced acute pancreatitis in rats
  122. The role of apoptosis in cisplatin-induced ototoxicity in rats
  123. Hydrogen Sulfide Prevents Ethanol-Induced Gastric Damage in Mice: Role of ATP-Sensitive Potassium Channels and Capsaicin-Sensitive Primary Afferent Neurons
  124. Light microscopy study of cisplatin-induced ototoxicity in rats
  125. Adjunctive Benefits of Systemic Etoricoxib in Non-Surgical Treatment of Aggressive Periodontitis: Short-Term Evaluation
  126. Effect of a combination of medium chain triglycerides, linoleic acid, soy lecithin and vitamins A and E on wound healing in rats
  127. Gastrointestinal dysmotility in 5-fluorouracil-induced intestinal mucositis outlasts inflammatory process resolution
  128. Alanyl-Glutamine and Glutamine Supplementation Improves 5-Fluorouracil-Induced Intestinal Epithelium Damage In Vitro
  129. Role of the NO/cGMP/KATPpathway in the protective effects of sildenafil against ethanol-induced gastric damage in rats
  130. Effects of a herbal gel containing carvacrol and chalcones on alveolar bone resorption in rats on experimental periodontitis
  131. Topically Applied Diterpenoids from Egletes viscosa (Asteraceae) Attenuate the Dermal Inflammation in Mouse Ear Induced by Tetradecanoylphorbol 13-Acetate- and Oxazolone
  132. Role of retinol in protecting epithelial cell damage induced by Clostridium difficile toxin A
  133. Modulation of acute visceral nociception and bladder inflammation by plant triterpene, α, β-amyrin in a mouse model of cystitis: role of tachykinin NK1-receptors, and K+ ATP channels
  134. Fucoidin Prevents Clostridium difficile Toxin-A-Induced Ileal Enteritis in Mice
  135. Lippia sidoides and Myracrodruon urundeuva gel prevents alveolar bone resorption in experimental periodontitis in rats
  136. Cyclooxygenase-2 expression on ifosfamide-induced hemorrhagic cystitis in rats
  137. Role of cytokines (TNF-α, IL-1β and KC) in the pathogenesis of CPT-11-induced intestinal mucositis in mice: effect of pentoxifylline and thalidomide
  138. Glutamine and alanyl-glutamine accelerate the recovery from 5-fluorouracil-induced experimental oral mucositis in hamster
  139. Antimicrobial activity of the essential oil from Lippia sidoides, carvacrol and thymol against oral pathogens
  140. Comparison of etoricoxib and indomethacin for the treatment of experimental periodontitis in rats
  141. Amifostine (Wr-2721) Prevents Indomethacin-Induced Gastric Damage in Rats: Role of Non-Protein Sulfhydryl Groups and Leukocyte Adherence
  142. A model of hemorrhagic cystitis induced with acrolein in mice
  143. Histological changes in bladders of patients submitted to ifosfamide chemotherapy even with mesna prophylaxis
  144. Role of nitric oxide on pathogenesis of 5-fluorouracil induced experimental oral mucositis in hamster
  145. Apolipoprotein E knockout mice have accentuated malnutrition with mucosal disruption and blunted insulin-like growth factor I responses to refeeding
  146. Peripheral antinociceptive effect of pertussis toxin: activation of the arginine/NO/cGMP/PKG/ ATP-sensitive K+channel pathway
  147. Angiotensin II potentiates inflammatory edema in rats: Role of mast cell degranulation
  148. Amifostine and glutathione prevent ifosfamide- and acrolein-induced hemorrhagic cystitis
  149. Effect of Novel A2A Adenosine Receptor Agonist ATL 313 on Clostridium difficile Toxin A-Induced Murine Ileal Enteritis
  150. Anti-nociceptive effect of thalidomide on zymosan-induced experimental articular incapacitation
  151. Caspase and Bid Involvement in Clostridium difficile Toxin A-Induced Apoptosis and Modulation of Toxin A Effects by Glutamine and Alanyl-Glutamine In Vivo and In Vitro
  152. Effect of Sodium Alendronate on Alveolar Bone Resorption in Experimental Periodontitis in Rats
  153. Glutamine depletion potentiates leucocyte-dependent inflammatory events induced by carrageenan or Clostridium difficile toxin A in rats
  154. Helianthus tuberosus agglutinin directly induces neutrophil migration, which can be modulated/inhibited by resident mast cells
  155. Pro-inflammatory effect of Arum maculatum lectin and role of resident cells
  156. Clostridium difficile Toxin A Induces Intestinal Epithelial Cell Apoptosis and Damage: Role of Gln and Ala-Gln in Toxin A Effects
  157. Angiotensin II Subtype 1 Receptor Blockade InhibitsClostridium difficileToxin A–Induced Intestinal Secretion in a Rabbit Model
  158. Effects of the tumour necrosis factor-alpha inhibitors pentoxifylline and thalidomide in short-term experimental oral mucositis in hamsters
  159. Nitric Oxide Synthase Inhibition Prevents Alveolar Bone Resorption in Experimental Periodontitis in Rats
  160. Protective effect of α- and β-amyrin, a triterpene mixture from Protium heptaphyllum (Aubl.) March. trunk wood resin, against acetaminophen-induced liver injury in mice
  161. Lectin of Pisum arvense seeds induces in-vivo and in-vitro neutrophil migration
  162. APOE4 Protects the Cognitive Development in Children with Heavy Diarrhea Burdens in Northeast Brazil
  163. Pathophysiology and Impact of Enteric Bacterial and Protozoal Infections: New Approaches to Therapy
  164. Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain
  165. Alanyl-glutamine hastens morphologic recovery from 5-fluorouracil–induced mucositis in mice
  166. Locally Applied Isosorbide Decreases Bone Resorption in Experimental Periodontitis in Rats
  167. Ternatin, a flavonoid, prevents cyclophosphamide and ifosfamide-induced hemorrhagic cystitis in rats
  168. Effects of Tumor Necrosis Factor-α Inhibitors Pentoxifylline and Thalidomide on Alveolar Bone Loss in Short-Term Experimental Periodontal Disease in Rats
  169. Intestinal Barrier Function and Secretion in Methotrexate-Induced Rat Intestinal Mucositis
  170. Use of dexamethasone with mesna for the prevention of ifosfamide-induced hemorrhagic cystitis
  171. Ternatin, an Anti-Inflammatory Flavonoid, Inhibits Thioglycolate-Elicited Rat Peritoneal Neutrophil Accumulation and LPS-Activated Nitric Oxide Production in Murine Macrophages
  172. Mechanism ofClostridium difficileToxin A–Induced Apoptosis in T84 Cells
  173. Pro-inflammatory effects of cholera toxin: role of tumor necrosis factor alpha
  174. Clostridium difficileToxin A Alters In Vitro–Adherent Neutrophil Morphology and Function
  175. Disodium Chlodronate Prevents Bone Resorption in Experimental Periodontitis in Rats
  176. Dual effect of cAMP on the writhing response in mice