All Stories

  1. Population-based outcome analysis of diffuse large B-cell lymphoma in people living with HIV infection and competent individuals
  2. Trabectedin is a novel chemotherapy agent for diffuse large B cell lymphoma
  3. Recent advances in understanding the biology of marginal zone lymphoma
  4. TCL1A interacts with TP63 and enhances the survival of Raji Burkitt lymphoma cell line
  5. Diffuse large B cell lymphoma cell of origin by digital expression profiling in the REAL07 Phase 1-2 study
  6. Preclinical evaluation of the BET bromodomain inhibitor BAY 1238097 for the treatment of lymphoma
  7. Lecture Notes: Oncology, 3rd Edition. Mark Bower and Jonathan Waxman. Wiley-Blackwell, 2016, Ebook/Paperback, 352 pp., Prices starting from 23.80 euros
  8. Inhibition of CHK 1 and WEE 1 as a new therapeutic approach in diffuse large B cell lymphomas with MYC deregulation
  9. Bayesian network data imputation with application to survival tree analysis
  10. The novel atypical retinoid ST5589 down-regulates Aurora Kinase A and has anti-tumour activity in lymphoma pre-clinical models
  11. Convergent Mutations and Kinase Fusions Lead to Oncogenic STAT3 Activation in Anaplastic Large Cell Lymphoma
  12. Interaction of CDCP1 with HER2 Enhances HER2-Driven Tumorigenesis and Promotes Trastuzumab Resistance in Breast Cancer
  13. The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs
  14. DNA methylation profiling identifies two splenic marginal zone lymphoma subgroups with different clinical and genetic features
  15. Genetic lesions in diffuse large B-cell lymphomas
  16. The transcription factor ETS1 in lymphomas: friend or foe?
  17. Advances in understanding the pathogenesis of systemic anaplastic large cell lymphomas
  18. Two types of BCR interactions are positively selected during leukemia development in the E -TCL1 transgenic mouse model of CLL
  19. A novel patient-derived tumorgraft model with TRAF1-ALK anaplastic large-cell lymphoma translocation
  20. 568 The BET bromodomain inhibitor OTX015 shows synergy with several anticancer agents in preclinical models of mantle cell lymphoma (MCL) and multiple myeloma (MM)
  21. Emerging Role of Infectious Etiologies in the Pathogenesis of Marginal Zone B-cell Lymphomas
  22. PRDM1/BLIMP1: a tumor suppressor gene in B and T cell lymphomas
  23. The Krüppel-like factor 2 transcription factor gene is recurrently mutated in splenic marginal zone lymphoma
  24. Abstract 2766: Inhibition of Chk1 and Wee1 as a new therapeutic approach in Mantle Cell Lymphoma
  25. Abstract CT402: A phase I study of inotuzumab ozogamicin (IO) in combination with temsirolimus (T) in patients (pts) with relapsed or refractory (R/R) CD22-positive (pos) B-cell non-Hodgkin lymphomas (NHL)
  26. Abstract 5528: The BET Bromodomain inhibitor OTX015 targets the NFKB, TLR and JAK/STAT pathways and shows pre-clinical activity as single agent and in combination in mature B-cell tumors
  27. Abstract 2604: Characterization of the activity and the mechanism of action of the new retinoid derivative ST5589 in pre-clinical models of lymphomas: involvement of MYC and cell cycle genes
  28. Abstract 739: The MEK-inhibitor pimasertib in B-cell lymphomas: Evaluation of the pre-clinical activity as single agent or in combination and identification of biomarkers of response
  29. Abstract 5531: OTX015, a novel BET inhibitor, is a promising anticancer agent for multiple myeloma
  30. Abstract 2219: STAT3 network dissection in ALK positive Anaplastic Large Cell Lymphomas
  31. Clinical Implications of Phosphorylated STAT3 Expression in De Novo Diffuse Large B-cell Lymphoma
  32. Physiopathogenesis of Hematological Cancer. Estela MariaNovak and Eduardo MagalhãesRego‬. Bentham Science Publishers, Sharjah, 2012, U.A.E. Ebook/Print-on-Demand, 255pp., USD 109/131
  33. Emerging Cancer Therapeutics: Lymphomas. John Sweetenham(guest editor). Demos Medical Publishing, 2012, New York, NY, USA. Hardcover edition, 389 pp., USD 85.00
  34. Chronic inflammation and extra-nodal marginal-zone lymphomas of MALT-type
  35. MYCnetwork mutations in high-risk chronic lymphocytic leukaemia
  36. Distinct patterns of global promoter methylation in early stage chronic lymphocytic leukemia
  37. Genome-wide DNA profiling identifies clonal heterogeneity in marginal zone lymphomas
  38. Whole-exome sequencing in splenic marginal zone lymphoma reveals mutations in genes involved in marginal zone differentiation
  39. Discovering Subgroups of Patients from DNA Copy Number Data Using NMF on Compacted Matrices
  40. Abstract A119: The BET-bromodomain inhibitor OTX015 shows synergism with several anticancer agents in preclinical models of diffuse large B-cell lymphoma (DLBCL).
  41. Abstract A219: OTX015, a bromodomain and extraterminal inhibitor, represents a novel agent for ALK positive anaplastic large cell lymphoma.
  42. Abstract A129: Novel histone deacetylase inhibitors ITF-A and ITF-B exhibit efficacy in preclinical models of mature B-cell lymphomas.
  43. Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma
  44. PRDM1/BLIMP1 is commonly inactivated in anaplastic large T-cell lymphoma
  45. Two main genetic pathways lead to the transformation of chronic lymphocytic leukemia to Richter syndrome
  46. Toward New Treatments for Mantle-Cell Lymphoma?
  47. Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma
  48. Promoter methylation patterns in Richter syndrome affect stem-cell maintenance and cell cycle regulation and differ fromde novodiffuse large B-cell lymphoma
  49. Beyond NPM-anaplastic lymphoma kinase driven lymphomagenesis
  50. The changing paradigm of chronic lymphocytic leukemia management
  51. Prognostic impact of monocyte count at presentation in mantle cell lymphoma
  52. MALT lymphoma: extranodal marginal zone B-cell lymphoma of MALT
  53. Genome-wide high resolution DNA profiling of hairy cell leukaemia
  54. Abstract 3853: Humanized NOD/Scid/IL2g-/- tumor grafts recapitulate primary anaplastic large cell lymphoma.
  55. Abstract 1017: The BRD-inhibitor OTX015 affects proliferation and gene expression of cells derived from mature lymphoid neoplasms.
  56. Risk factors of central nervous system relapse in mantle cell lymphoma
  57. Large genomic aberrations detected by SNP array are independent prognosticators of a shorter time to first treatment in chronic lymphocytic leukemia patients with normal FISH
  58. MALT Lymphoma (Extranodal Marginal Zone B-Cell Lymphoma)
  59. Genome-Wide DNA Profiling of HIV-Related B-Cell Lymphomas
  60. Where Do We Stand in the Genomics of Lymphomas?
  61. Gains ofCCND3gene in ocular adnexal MALT lymphomas: an integrated analysis
  62. Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia
  63. MGA, a suppressor ofMYC, is recurrently inactivated in high risk chronic lymphocytic leukemia
  64. 528 The BRD-inhibitor OTX015 Shows Pre-clinical Activity in Diffuse Large B-cell Lymphoma (DLBCL)
  65. Gela histological scoring system for post-treatment biopsies of patients with gastric MALT lymphoma is feasible and reliable in routine practice
  66. The coding genome of splenic marginal zone lymphoma: activation of NOTCH2 and other pathways regulating marginal zone development
  67. Chlamydophila Psittaci Eradication With Doxycycline As First-Line Targeted Therapy for Ocular Adnexae Lymphoma: Final Results of an International Phase II Trial
  68. Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma
  69. Genetic alterations in systemic nodal and extranodal non-cutaneous lymphomas derived from mature T cells and natural killer cells
  70. An Open-Label Phase 2 Study of Twice-Weekly Bortezomib and Intermittent Pegylated Liposomal Doxorubicin in Patients With Ovarian Cancer Failing Platinum-Containing Regimens
  71. MYD88 somatic mutations in MALT lymphomas
  72. Abstract 4575: Three-gene diagnostic classifier for ALK negative ALCL
  73. Incidence, risk factors and outcome of histological transformation in follicular lymphoma
  74. A multicenter phase II trial (SAKK 36/06) of single-agent everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma
  75. Disruption of BIRC3 associates with fludarabine chemorefractoriness in TP53 wild-type chronic lymphocytic leukemia
  76. IGHV gene mutational status and 17p deletion are independent molecular predictors in a comprehensive clinical-biological prognostic model for overall survival prediction in chronic lymphocytic leukemia
  77. Multiple myeloma shows no intra-disease clustering of immunoglobulin heavy chain genes
  78. Absence of NOTCH1 gene mutations in MALT lymphomas
  79. Integrated DNA copy number and methylation profiling of lymphoid neoplasms using a single array
  80. Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness
  81. Saliva is a reliable and practical source of germline DNA for genome-wide studies in chronic lymphocytic leukemia
  82. Alteration of BIRC3 and multiple other NF- B pathway genes in splenic marginal zone lymphoma
  83. Genomic aberrations affecting the outcome of immunodeficiency-related diffuse large B-cell lymphoma
  84. Molecular history of Richter syndrome: origin from a cell already present at the time of chronic lymphocytic leukemia diagnosis
  85. Genome-wide DNA profiling better defines the prognosis of chronic lymphocytic leukaemia
  86. Clinical and molecular characterization of diffuse large B-cell lymphomas with 13q14.3 deletion
  87. Del(13q14.3) length matters: an integrated analysis of genomic, fluorescence in situ hybridization and clinical data in 169 chronic lymphocytic leukaemia patients with 13q deletion alone or a normal karyotype
  88. Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation
  89. Biased immunoglobulin genes rearrangement in mantle cell lymphoma: Hints to identify the normal B-cell counterpart
  90. Chromosome 11q23.1 is an unstable region in B-cell tumor cell lines
  91. 13q14 Deletion size and number of deleted cells both influence prognosis in chronic lymphocytic leukemia
  92. Anaplastic lymphoma kinase in human cancer
  93. Gains of MYC locus and outcome in patients with diffuse large B-cell lymphoma treated with R-CHOP
  94. Genomic profiles of MALT lymphomas: variability across anatomical sites
  95. Integrated profiling of diffuse large B‐cell lymphoma with 7q gain
  96. In vitro efficacy of tyrosine kinase inhibitors: SYK and BCR-ABL inhibitors in lymphomas
  97. Diffuse large B-cell lymphoma with concordant bone marrow involvement has peculiar genomic profile and poor clinical outcome
  98. B-cell receptor, clinical course and prognosis in chronic lymphocytic leukaemia: the growing saga of the IGHV3 subgroup gene usage
  99. Mutations of CD79A, CD79B and EZH2 genes in immunodeficiency-related non-Hodgkin lymphomas
  100. The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation
  101. Genome-wide DNA profiling of marginal zone lymphomas identifies subtype-specific lesions with an impact on the clinical outcome
  102. Immunogenetics features and genomic lesions in splenic marginal zone lymphoma
  103. Hierarchical clustering analysis of pathologic and molecular data identifies prognostically and biologically distinct groups of colorectal carcinomas
  104. Syk expression patterns differ among B-cell lymphomas
  105. Genomic lesions associated with a different clinical outcome in diffuse large B-Cell lymphoma treated with R-CHOP-21
  106. Multicentre validation of a prognostic index for overall survival in chronic lymphocytic leukaemia
  107. Treatment of gastric marginal zone lymphoma of MALT type
  108. An integrated Bayesian analysis of LOH and copy number data
  109. Patterns of survival of follicular lymphomas at a single institution through three decades
  110. Stereotyped patterns of B-cell receptor in splenic marginal zone lymphoma
  111. Non-negative matrix factorization to perform unsupervised clustering of genome wide DNA profiles in mature B cell lymphoid neoplasms
  112. Perivascular expression of CXCL9 and CXCL12 in primary central nervous system lymphoma: T-cell infiltration and positioning of malignant B cells
  113. The clinical and biological features of a series of immunophenotypic variant of B-CLL
  114. 3 Pathogenesis of ocular adnexal lymphoma
  115. 57 High-resolution genomic profiling of 533 B-cell lymphomas defines distinct tumor signatures, genomic aberrations correlated with outcome and pathogenetic subgroups
  116. IGHD3-3fails to behave as unfavourable prognostic marker in chronic lymphocytic leukaemia
  117. Molecular and clinical features of chronic lymphocytic leukemia with stereotyped B-cell receptors in a Ukrainian cohort
  118. Single nucleotide polymorphism-arrays provide new insights in the pathogenesis of post-transplant diffuse large B-cell lymphoma
  119. Expression of Mutated IGHV3-23 Genes in Chronic Lymphocytic Leukemia Identifies a Disease Subset with Peculiar Clinical and Biological Features
  120. Serotonin Receptor 3A Expression in Normal and Neoplastic B Cells
  121. Genome wide DNA-profiling of HIV-related B-cell lymphomas
  122. Genomic profiling of Richter's syndrome: recurrent lesions and differences with de novo diffuse large B-cell lymphomas
  123. A multicentre phase II trial of gemcitabine for the treatment of patients with newly diagnosed, relapsed or chemotherapy resistant mantle cell lymphoma: SAKK 36/03
  124. Hairy cell leukemias with unmutated IGHV genes define the minor subset refractory to single-agent cladribine and with more aggressive behavior
  125. A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: An integrated genomics approach reveals a wide gene dosage effect
  126. The prognosis of clinical monoclonal B cell lymphocytosis differs from prognosis of Rai 0 chronic lymphocytic leukaemia and is recapitulated by biological risk factors
  127. Stereotyped B-Cell Receptor Is an Independent Risk Factor of Chronic Lymphocytic Leukemia Transformation to Richter Syndrome
  128. Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma
  129. BCL2, BCL6, MYC, MALT 1, and BCL10 rearrangements in nodal diffuse large B-cell lymphomas: a multicenter evaluation of a new set of fluorescent in situ hybridization probes and correlation with clinical outcome
  130. The NF- B negative regulator TNFAIP3 (A20) is inactivated by somatic mutations and genomic deletions in marginal zone lymphomas
  131. Long-term outcome following Helicobacter pylori eradication in a retrospective study of 105 patients with localized gastric marginal zone B-cell lymphoma of MALT type
  132. Molecular and clinical features of chronic lymphocytic leukaemia with stereotyped B cell receptors: results from an Italian multicentre study
  133. Analysis of the host pharmacogenetic background for prediction of outcome and toxicity in diffuse large B-cell lymphoma treated with R-CHOP21
  134. Bayesian DNA copy number analysis
  135. Bayesian Joint Estimation of CN and LOH Aberrations
  136. Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance
  137. Marginal Zone Lymphomas
  138. Up-regulation of the hypoxia-inducible factor–1 transcriptional pathway in colorectal carcinomas
  139. 195 POSTER Pharmacogenomic analysis of the peripheral blood cell transcriptome in patients with advanced solid tumors treated with the mTOR inhibitor deforolimus (AP23573; MK 8669) in phase Ib studies
  140. Immunoreactivity for cyclin D1 is a reliable marker of gene aberration in plasma cell myeloma but does not specify patients prognosis
  141. Phase I study of bortezomib with weekly paclitaxel in patients with advanced solid tumours
  142. Genome-wide DNA analysis identifies recurrent imbalances predicting outcome in chronic lymphocytic leukaemia with 17p deletion
  143. Pathobiology and molecular basis of MALT lymphoma
  144. High density genome-wide DNA profiling reveals a remarkably stable profile in hairy cell leukaemia
  145. Ocular adnexal MALT lymphoma: an intriguing model for antigen-driven lymphomagenesis and microbial-targeted therapy
  146. Hematological Oncology: further ahead
  147. The strength of T cell stimulation determines IL-7 responsiveness, secondary expansion, and lineage commitment of primed human CD4+IL-7Rhi T cells
  148. Oncogenic BARD1 Isoforms Expressed in Gynecological Cancers
  149. Reactive perivascular T-cell infiltrate predicts survival in primary central nervous system B-cell lymphomas
  150. Simultaneous occurrence of peripheral T-cell lymphoma unspecified and B-cell small lymphocytic lymphoma. Report of 2 cases
  151. Molecular characterization of human multiple myeloma cell lines by integrative genomics: Insights into the biology of the disease
  152. Bendamustine in lymphomas: More to combine?
  153. ConcomitantMYCand microRNA cluster miR-17-92 (C13orf25) amplification in human mantle cell lymphoma
  154. The cellular origin of mantle cell lymphoma
  155. Chromosome instability and translocation t(11;18) in primary gastric marginal zone B-cell lymphoma of MALT-type
  156. Low prevalence ofChlamydia psittaciin ocular adnexal lymphomas from Cuban patients
  157. Cyclin-dependent kinase inhibitor seliciclib showsin vitroactivity in diffuse large B-cell lymphomas
  158. A Virtual Tissue Bank for Primary Central Nervous System Lymphomas in Immunocompetent Individuals
  159. Integrative genomic analysis reveals distinct transcriptional and genetic features associated with chromosome 13 deletion in multiple myeloma
  160. Chlamydia or Not Chlamydia, That Is the Question: Which Is the Microorganism Associated With MALT Lymphomas of the Ocular Adnexa?
  161. Cellular, Molecular Consequences of Peroxisome Proliferator- Activated Receptor-δ Activation in Ovarian Cancer Cells
  162. Comparative genome-wide profiling of post-transplant lymphoproliferative disorders and diffuse large B-cell lymphomas
  163. Chromosome band 6q deletion pattern in malignant lymphomas
  164. Update on the molecular biology of mantle cell lymphoma
  165. Marginal Zone B-Cell Lymphomas
  166. Delving deeper into MALT lymphoma biology
  167. Identification of T Cell-Restricted Genes, and Signatures for Different T Cell Responses, Using a Comprehensive Collection of Microarray Datasets
  168. Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma
  169. State-of-the-Art Therapeutics: Marginal-Zone Lymphoma
  170. Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1–polarizing program in dendritic cells
  171. IgVH mutations in blastoid mantle cell lymphoma characterize a subgroup with a tendency to more favourable clinical outcome
  172. Identification of a potential role forPOU2AF1 andBTG4 in the deletion of 11q23 in chronic lymphocytic leukemia
  173. Mantle cell lymphoma
  174. 546 A novel aureolic acid antibiotic analogue has potent anti-proliferative activity and induces multiple changes in gene expression in ovarian cancer cells
  175. 66 Anti-proliferative activity of a PPAR gamma agonist is associated with changes in the expression of cell cycle and apoptosis related genes in human ovarian cancer cells
  176. Immunoglobulin heavy chain genes somatic hypermutations and chromosome 11q22-23 deletion in classic mantle cell lymphoma: a study of the Swiss Group for Clinical Cancer Research
  177. Molecular basis of mantle cell lymphoma
  178. Role of DNA methylation in the suppression of Apaf-1 protein in human leukaemia
  179. Mantle Cell Lymphoma: New Treatments Targeted to the Biology
  180. The class II tumour suppressor gene RARRES3 maps to 11q12, not 11q23
  181. Genetic alterations underlying the pathogenesis of MALT lymphoma
  182. Application of genomic real-time PCR to characterise 11q deletions in mantle cell lymphoma and chronic lymphocytic leukaemia
  183. Gastric MALT lymphomas prospective LY03 randomised cooperative trial: preliminary results of the molecular follow-up
  184. Construction of a chromosome 11q22–23 BAC/PAC contig to characterize deletions in lymphoproliferative disorders
  185. MALT lymphoma and other marginal zone lymphomas
  186. Prognostic models for diffuse large b‐cell lymphoma
  187. Analysis ofFas/CD95 gene somatic mutations in ovarian cancer cell lines
  188. Analysis of Fas/CD95 gene somatic mutations in ovarian cancer cell lines
  189. BCL10 gene mutations rarely occur in lymphoid malignancies
  190. Molecular detection of circulating neoplastic cells in patients with clinically localised gastric and non-gastric mucosa-associated lymphoid tissue lymphoma
  191. Molecular analysis of low grade extranodal marginal zone B-cell lymphoma by alumorph genotyping
  192. Association of gastric and Waldeyer's ring lymphoma: a molecular study
  193. Lack of CD95/FAS gene somatic mutations in extranodal, nodal and splenic marginal zone B cell lymphomas
  194. Eradication of Borrelia burgdorferi infection in primary marginal zone B-cell lymphoma of the skin
  195. Extranodal Marginal Zone B-Cell Lymphoma Genotyping byAlu— Polymerase Chain Reaction
  196. Prognostic models for diffuse large b-cell lymphoma
  197. The effect of Rituximab on patients with follicular and mantle-cell lymphoma
  198. CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers
  199. CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers
  200. DNA fingerprinting of low-grade extranodal marginal zone B-cell lymphoma (of MALT type)
  201. CHK1 frameshift mutations in genetically unstable colorectal and endometrial cancers
  202. Molecular Genetics of Extranodal Marginal Zone (MALT-Type) B-Cell Lymphoma
  203. Immunoglobulin Light Chain Kappa Deletion Rearrangement as a Marker of Clonality in Mantle Cell Lymphoma
  204. Primary Mediastinal Large B-Cell Lymphoma: The Need for Prospective Controlled Clinical Trials
  205. Primary Mediastinal Large B-Cell Lymphoma (PMLCL): The Need for Prospective Controlled Clinical Trials
  206. Management of rare forms of lymphoma
  207. Cardiac involvement in HIV-related non-Hodgkin's lymphoma: a case report and short review of the literature
  208. Primary extranodal lymphoma of skeletal muscles: a report of four cases.
  209. Molecular Analysis of the Progression from Helicobacter pylori –Associated Chronic Gastritis to Mucosa-Associated Lymphoid-Tissue Lymphoma of the Stomach
  210. Autoreactive B cell clones in marginal-zone B cell lymphoma (MALT lymphoma) of the stomach
  211. Primary mediastinal diffuse large cell lymphoma (PMLCL): The experience of the servizio di radioterapia and the servizio oncologico cantonale, Ospedale San Giovanni Bellinzona
  212. Immunoglobulin heavy chain Diversity genes rearrangement pattern indicates that MALT‐type gastric lymphoma B cells have undergone an antigen selection process
  213. Clinical significance of bcl-2 (MBR)/JH rearrangement in the peripheral blood of patients with diffuse large B-cell lymphomas
  214. MALT and other marginal zone lymphomas
  215. B-cell chronic lymphocytic leukemia