All Stories

  1. Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice

    Article • International Journal of Molecular Sciences, February 2021, MDPI AG

    PhD Francesca Virginia Bruschi

  2. PNPLA3 I148M Up-Regulates Hedgehog and Yap Signaling in Human Hepatic Stellate Cells

    Article • International Journal of Molecular Sciences, November 2020, MDPI AG

    PhD Francesca Virginia Bruschi

  3. The Role of Metabolic Lipases in the Pathogenesis and Management of Liver Disease

    Article • Hepatology, September 2020, Wolters Kluwer Health

    PhD Francesca Virginia Bruschi

  4. Metabolic regulation of hepatic PNPLA3 expression and severity of liver fibrosis in patients with NASH

    Article • Liver International, February 2020, Wiley

    PhD Francesca Virginia Bruschi

  5. Monoacylglycerol lipase inhibition protects from liver injury in mouse models of sclerosing cholangitis

    Article • Hepatology, September 2019, Wiley

    PhD Francesca Virginia Bruschi

  6. I148M PNPLA3 hepatic stellate cells display lower LXR activity compared to wt PNPLA3

    Article • Hepatology Communications, July 2019, Wiley

    PhD Francesca Virginia Bruschi

  7. Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption

    Article • Journal of Lipid Research, May 2019, American Society for Biochemistry & Molecular Biology (ASBMB)

    PhD Francesca Virginia Bruschi

  8. Nuclear Receptor Regulation of Aquaglyceroporins in Metabolic Organs

    Article • International Journal of Molecular Sciences, June 2018, MDPI AG

    PhD Francesca Virginia Bruschi

  9. PNPLA3 I148M by disrupting PPAR gamma signaling regulates aquaporin 3 in stellate cells

    Article • Scientific Reports, November 2017, Nature

    thierry claudel, PhD Francesca Virginia Bruschi

  10. how PNPLA3 polymorphism impacts on liver homeostasis

    Article • Hepatic Medicine Evidence and Research, November 2017, Dove Medical Press

    PhD Francesca Virginia Bruschi, thierry claudel

  11. adiponectin by regulating PPAR alpha activity regulates aquaporin 3 in HSC

    Article • Biochemical and Biophysical Research Communications, August 2017, Elsevier

    thierry claudel, PhD Francesca Virginia Bruschi

  12. PNPLA3 mutant lowers PPARg signaling in HSC

    Article • Hepatology, April 2017, Wiley

    PhD Francesca Virginia Bruschi, thierry claudel, Fabio Marra