All Stories

  1. Substituted Benzofurans as Potent Anticancer Agents: Advances, Molecular Docking, and SAR Studies
  2. An Emerging Approach of Senotherapeutics for the Treatment of Lung Disorders
  3. Recent Development of Zolmitriptan Formulation in Migraine Therapy: Production, Metabolism and Pharmaceutical Aspects
  4. Significance of Triazole in Medicinal Chemistry: Advancement in Drug Design, Reward and Biological Activity
  5. Synthesis and biological evaluation of some novel benzoxazin-4-one and quinazolin-4-one derivatives based on anti-inflammatory commercial drugs
  6. Benzothiazole‐based apoptosis inducers: A comprehensive overview and future prospective
  7. Thiazolobenzamide‐Naphthalene Hybrids as Potent Anticancer agents compared to Doxorubicin: Design, Synthesis, SAR, In‐silico and Toxicity Analysis
  8. Prodrug Rewards in Medicinal Chemistry: An Advance and Challenges Approach for Drug Designing
  9. A Review on the Synthesis and Anticancer Potentials of Imidazothiazole Derivatives
  10. Molecular Docking and In Vitro Anticancer Screening of Synthesized Arylthiazole linked 2H-indol-2-one Derivatives as VEGFR-2 Kinase Inhibitors
  11. Current Status of Novel Pyridine Fused Derivatives as Anticancer Agents: An Insight into Future Perspectives and Structure Activity Relationship (SAR)
  12. Coumarin linked heterocyclic hybrids: A promising approach to develop multi target drugs for Alzheimer's disease
  13. Synthesis, Molecular Docking, and Biological Evaluation of Some Novel 2-(5-Substituted 1,3,4-oxadiazole-2-yl)-1,3-benzothiazole Derivatives as Anticonvulsant Agents
  14. A Mini Review on Recent Advancements in the Therapeutic Potentials of Benzothiazoles
  15. APPROACHES FOR CHEMICAL SYNTHESIS AND DIVERSE PHARMACOLOGICAL SIGNIFICANCE OF PYRAZOLONE DERIVATIVES: A REVIEW
  16. Identification of metabolic pathways involved in the biotransformation of eslicarbazepine acetate using UPLC-MS/MS, human microsomal enzymes and in silico studies
  17. Recent advances in the development of chemotherapeutic agents for malaria.
  18. Synthesis, ADMET prediction and reverse screening study of 3,4,5-trimethoxy phenyl ring pendant sulfur‐containing cyanopyrimidine derivatives as promising apoptosis inducing anticancer agents
  19. Diverse Pharmacological Potential of Various Furanone Derivatives: A Mini-Review
  20. A review on synthetic procedures and applications of phosphorus oxychloride (POCl3) in the last biennial period (2018–19)
  21. Synthesis, in vitro cytotoxicity, ADME, and molecular docking studies of benzimidazole‐bearing furanone derivatives
  22. Design, synthesis, and biological evaluation of imidazopyridine‐linked thiazolidinone as potential anticancer agents
  23. SYNTHESIS AND SAR STRATEGY OF THIAZOLIDINEDIONE: A NOVEL APPROACH FOR CANCER TREATMENT
  24. A novel polyherbal formulation containing thymoquinone attenuates carbon tetrachloride-induced hepatorenal injury in a rat model
  25. Targeting malaria and leishmaniasis: Synthesis and pharmacological evaluation of novel pyrazole-1,3,4-oxadiazole hybrids. Part II
  26. Insights into the chemistry and therapeutic potential of furanones: A versatile pharmacophore
  27. Recent Advances towards Treatment of HIV: Synthesis and SAR Studies
  28. Synthesis, ADME, docking studies and in vivo anti-hyperglycaemic potential estimation of novel Schiff base derivatives from octadec-9-enoic acid
  29. Novel hybrids of benzothiazole-1,3,4-oxadiazole-4-thiazolidinone: Synthesis, in silico ADME study, molecular docking and in vivo anti-diabetic assessment
  30. Studies on new substituted pyridazinones: synthesis and biological evaluation
  31. Newly Synthesized Oxadiazole Based Mannich Base Derivatives of Fatty Acid: in Silico Study and in Vivo Anti-Hyperglycaemic Estimation
  32. A comprehensive review on Brigatinib – A wonder drug for targeted cancer therapy in non-small cell lung cancer
  33. Synthesis, molecular docking with COX 1& II enzyme, ADMET screening and in vivo anti-inflammatory activity of oxadiazole, thiadiazole and triazole analogs of felbinac
  34. Synthesis, molecular modelling studies and ADME prediction of benzothiazole clubbed oxadiazole-Mannich bases, and evaluation of their anti-diabetic activity through in vivo model
  35. Development of a stress induced validated UPLC-PDA method for the analysis of Eslicarbazepine acetate
  36. Nalidixic Acid Schiff Bases: Synthesis and Biological Evaluation
  37. Ameliorative effect of camel's milk and Nigella Sativa Oil against thioacetamide-induced hepatorenal damage in rats
  38. PI3K signaling pathway targeting by using different molecular approaches to treat cancer
  39. Chemical modification of acetaminophen: PASS assistedin vivo anti-inflammatory activity of chalcones, flavanones and Schiff bases
  40. Phenothiazines and Related Drugs as Multi Drug Resistance Reversal Agents in Cancer Chemotherapy Mediated by p-glycoprotein
  41. Oxidative Cyclization of Isoniazid with Fluoroquinolones: Synthesis, Antibacterial and Antitubercular Activity of New 2,5-disubstituted-1,3,4-Oxadiazoles
  42. Phytochemistry and potential therapeutic actions of Boswellic acids: A mini-review
  43. Design, synthesis and cytotoxic evaluation of novel imidazolone fused quinazolinone derivatives
  44. Novel 2,4-dichlorophenoxy acetic acid substituted thiazolidin-4-ones as anti-inflammatory agents: Design, synthesis and biological screening
  45. Forced Degradation Studies
  46. Quinoline based furanones and their nitrogen analogues: Docking, synthesis and biological evaluation
  47. Rational Design and Synthesis of Biologically Active Disubstituted 2(3H) Furanones and Pyrrolone Derivatives as Potent and Safer Non Steroidal Anti-inflammatory Agents
  48. Synthesis, antimicrobial and antitubercular activities of some novel pyrazoline derivatives
  49. Synthesis, Molecular Docking and Potential Antioxidant Activity of Di/Trisubstituted Pyridazinone Derivatives
  50. Synthesis, Biological Evaluation and Pharmacokinetic Studies of Mefenamic Acid - N-Hydroxymethylsuccinimide Ester Prodrug as Safer NSAID
  51. Synthesis and biological evaluation of a mutual prodrug of norfloxacin and fenbufen
  52. A review on dronedarone: Pharmacological, pharmacodynamic and pharmacokinetic profile
  53. Synthesis and in vivo diuretic activity of some new benzothiazole sulfonamides containing quinoxaline ring system
  54. Molecular modeling and synthesis of some new 2-imino-4-thiazolidinone derivatives with promising TNF-α inhibitory activity
  55. Synthesis, molecular properties, toxicity and biological evaluation of some new substituted imidazolidine derivatives in search of potent anti-inflammatory agents
  56. Design and synthesis of benzimidazoles containing substituted oxadiazole, thiadiazole and triazolo-thiadiazines as a source of new anticancer agents
  57. Design and synthesis of butenolide-based amide derivatives as anti-inflammatory agents
  58. Synthesis and biological evaluation of new hydrazide-Schiff bases
  59. Design, synthesis, molecular properties and antimicrobial activities of some novel 2(3H) pyrrolone derivatives
  60. Design and Synthesis of Butenolide-based Novel Benzyl Pyrrolones: Their TNF-αbased Molecular Docking withIn vivoandIn vitroAnti-inflammatory Activity
  61. Design, synthesis and biological evaluation of piperic acid triazolyl derivatives as potent anti-inflammatory agents
  62. Quantification of total phenol, flavonoid content and pharmacognostical evaluation including HPTLC fingerprinting for the standardization of Piper nigrum Linn fruits
  63. Structure Assessment Analysis of Core Domain of Seven Protein Data Bank Entries of HIV-1 Protease Using Different in-silico Techniques
  64. Attenuation of inflammatory mediators, oxidative stress and toxic risk evaluation of Aporosa lindleyana Baill bark extract
  65. Design and synthesis of pyrimidine molecules endowed with thiazolidin-4-one as new anticancer agents
  66. Anticancer Activity of New Compounds Using Benzimidazole as a Scaffold
  67. Essential aminoacid incorporated GABA–phthalimide derivatives: synthesis and anticonvulsant evaluation
  68. Synthesis, characterization, in vitro antimicrobial, and anthelmintic evaluations of 2-(4-chloro-3-methylphenoxy)-N′-[{5′-(substituted aryl)-furan-2′-yl}-methylidene]-acetohydrazides
  69. Application of LC–MS/MS for quantitative analysis of glucocorticoids and stimulants in biological fluids
  70. Synthesis, biological activities, and pharmacokinetics studies of a mutual prodrug of aceclofenac and paracetamol
  71. Anticonvulsant and Antitubercular Activities of 6-Phenyl/Biphenyl-4-yl-2- [2-(pyridin-2-ylamino)-ethyl]- and 6-(Biphenyl-4yl)-2-(2N-subtituted amin- 1-yl)-ethyl derivatives of 4,5-dihydropyridazin-3(2H)-one
  72. Analytical methods for the detection of undeclared synthetic drugs in traditional herbal medicines as adulterants
  73. A review on therapeutic potential of Nigella sativa: A miracle herb
  74. Synthesis and Biological Evaluation of Novel Substituted-Imidazolidine Derivatives
  75. Benzimidazole clubbed with triazolo-thiadiazoles and triazolo-thiadiazines: New anticancer agents
  76. Docking studies on butenolide derivatives as Cox-II inhibitors
  77. Synthesis and biological evaluation of di- and tri-substituted imidazoles as safer anti-inflammatory-antifungal agents
  78. Benzimidazole bearing oxadiazole and triazolo-thiadiazoles nucleus: Design and synthesis as anticancer agents
  79. Pharmacophore modeling studies on N-hydroxyphenyl acrylamides and N-hydroxypyridin-2-yl-acrylamides as inhibitor of human cancer leukemia K562 cells
  80. Synthesis of benzimidazoles bearing oxadiazole nucleus as anticancer agents
  81. 1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one
  82. Synthesis and antimicrobial activity of bischalcone derivatives
  83. Quinolone derivatives as antitubercular drugs
  84. Design, synthesis and antihypertensive screening of novel pyridazine substituted s-triazin-2-imine/one/thione derivatives
  85. Microbiological evaluation of 4-substituted-imidazolidine derivatives
  86. SYNTHESIS, CHARACTERIZATION AND ANTIHYPERTENSIVE ACTIVITY OF SOME NEW SUBSTITUTED PYRIDAZINE DERIVATIVES
  87. Heterocyclic compounds as carbonic anhydrase inhibitor
  88. 7-Phenyl-3,4,8,9-tetrahydro-2H-pyridazino[1,6-a][1,3,5]triazin-2-imine
  89. Triazole incorporated pyridazinones as a new class of antihypertensive agents: Design, synthesis and in vivo screening
  90. Synthesis and biological evaluation of some new pyridazinone derivatives
  91. Synthesis of quinoline attached-furan-2(3H)-ones having anti-inflammatory and antibacterial properties with reduced gastro-intestinal toxicity and lipid peroxidation
  92. Synthesis, antiinflammatory and antimicrobial activity of some new 1-(3-Phenyl-3,4-Dihydro-2H-1,3-Benzoxazin-6-yl)-ethanone derivatives
  93. SYNTHESIS AND ANTITUBERCULAR ACTIVITY OF PYRIDAZINONE DERIVATIVES
  94. 6-Phenyl-2-(4-phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)-4,5-dihydropyridazin-3(2H)-one
  95. NEW AMIDES OF SULPHONAMIDES: SYNTHESIS AND BIOLOGICAL EVALUATION
  96. SYNTHESIS AND MICROBIOLOGICAL EVALUATION OF MANNICH BASES DERIVED FROM 4,6-DIACETYLRESORCINOL
  97. Studies on fused heterocyclic 3,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazoles: synthesis and biological evaluation
  98. Antimicrobial activities of some synthetic butenolides and their pyrrolone derivatives
  99. Synthesis of 6-aminomethyl derivatives of benzopyran-4-one with dual biological properties: Anti-inflammatory-analgesic and antimicrobial
  100. 3-Arylidene-5-(4-isobutylphenyl)-2(3H)-furanones: a new series of anti-inflammatory and analgesic compounds having antimicrobial activity
  101. Fenbufen based 3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-ones as safer antiinflammatory and analgesic agents
  102. Synthesis and pharmacological evaluation of 2(3H)-furanones and 2(3H)-pyrrolones, combining analgesic and anti-inflammatory properties with reduced gastrointestinal toxicity and lipid peroxidation
  103. Aroylpropionic acid based 2,5-disubstituted-1,3,4-oxadiazoles: Synthesis and their anti-inflammatory and analgesic activities
  104. Synthesis and evaluation of in vitro antiviral activity of 2-[3-(substituted phenyl)-4,5-dihydro-1H-5-pyrazolyl]benzofuran-3-yl chloride derivatives
  105. Synthesis of novel 1,3,4-oxadiazole derivatives and their biological properties
  106. Synthesis and biological evaluation of β -aroylpropionic acid based 1,3,4-oxadiazoles
  107. Synthesis, reactions and biological activity of 3-arylidene-5-(4-methylphenyl)-2(3H)-furanones?
  108. Synthesis of 1-(4-phenoxyphenyl)-3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]propan-1-ones as safer anti-inflammatory and analgesic agents
  109. Antibacterial and antifungal activities of 2-arylidene-4-(4-methylphenyl)but-3-en-4-olides and their pyrrolone derivatives
  110. 2-Arylidene-4-(4-phenoxy-phenyl)but-3-en-4-olides: Synthesis, reactions and biological activity
  111. SYNTHESIS AND ANTIBACTERIAL EVALUATION OF NEW FLAVONOID DERIVATIVES FROM 4,6-DIACETYL RESORCINOL
  112. SYNTHESIS OF SOME NEW PRODRUGS OF SULPHONAMIDES AND STUDIES ON THEIR ANTIMICROBIAL AND ANTI-INFLAMMATORY ACTION