All Stories

  1. Extracellular Lactic Acidosis of the Tumor Microenvironment Drives Adipocyte-to-Myofibroblast Transition Fueling the Generation of Cancer-Associated Fibroblasts
  2. Nintedanib-αVβ6 Integrin Ligand Conjugates Reduce TGFβ-Induced EMT in Human Non-Small Cell Lung Cancer
  3. Extracellular Acidosis Differentially Regulates Estrogen Receptor β-Dependent EMT Reprogramming in Female and Male Melanoma Cells
  4. miR-214-Enriched Extracellular Vesicles Released by Acid-Adapted Melanoma Cells Promote Inflammatory Macrophage-Dependent Tumor Trans-Endothelial Migration
  5. An Oleocanthal-Enriched EVO Oil Extract Induces the ROS Production in Gastric Cancer Cells and Potentiates the Effect of Chemotherapy
  6. Oleuropein-Rich Leaf Extract as a Broad Inhibitor of Tumour and Macrophage iNOS in an Apc Mutant Rat Model
  7. Oleuropein-Rich Leaf Extract as a Broad Inhibitor of Tumour and Macrophage iNOS in Apc Mutant Rat Model
  8. Enhanced Vasculogenic Capacity Induced by 5-Fluorouracil Chemoresistance in a Gastric Cancer Cell Line
  9. Glycolysis-derived acidic microenvironment as a driver of endothelial dysfunction in systemic sclerosis
  10. uPAR-expressing melanoma exosomes promote angiogenesis by VE-Cadherin, EGFR and uPAR overexpression and rise of ERK1,2 signaling in endothelial cells
  11. The acidic tumor microenvironment drives a stem-like phenotype in melanoma cells
  12. Cancer Glycolytic Dependence as a New Target of Olive Leaf Extract
  13. uPAR Knockout Results in a Deep Glycolytic and OXPHOS Reprogramming in Melanoma and Colon Carcinoma Cell Lines
  14. The Carbonic Anhydrase IX inhibitor SLC-0111 as emerging agent against the mesenchymal stem cell-derived pro-survival effects on melanoma cells
  15. FDG uptake in cancer: a continuing debate
  16. A potentiated cooperation of carbonic anhydrase IX and histone deacetylase inhibitors against cancer
  17. Potential Role of HLA Class I Antigens in the Glycolytic Metabolism and Motility of Melanoma Cells
  18. Anoikis Resistance as a Further Trait of Acidic-Adapted Melanoma Cells
  19. Cell-targeted c(AmpRGD)-sunitinib molecular conjugates impair tumor growth of melanoma
  20. EGFR/uPAR interaction as druggable target to overcome vemurafenib acquired resistance in melanoma cells
  21. Oleuropein, the Main Polyphenol of Olea europaea Leaf Extract, Has an Anti-Cancer Effect on Human BRAF Melanoma Cells and Potentiates the Cytotoxicity of Current Chemotherapies
  22. SOX2 as a novel contributor of oxidative metabolism in melanoma cells
  23. The carbonic anhydrase IX inhibitor SLC-0111 sensitises cancer cells to conventional chemotherapy
  24. Everolimus selectively targets vemurafenib resistant BRAFV600E melanoma cells adapted to low pH
  25. Carbonic anhydrase IX inhibition affects viability of cancer cells adapted to extracellular acidosis
  26. Type II CRISPR/Cas9 approach in the oncological therapy
  27. The acidic microenvironment as a possible niche of dormant tumor cells
  28. Acidity of Microenvironment as a Further Driver of Tumor Metabolic Reprogramming
  29. Targeting the receptor tyrosine kinase RET in combination with aromatase inhibitors in ER positive breast cancer xenografts
  30. Roles of different IRES-dependent FGF2 isoforms in the acquisition of the major aggressive features of human metastatic melanoma
  31. Radiosynthesis and micro-SPECT analysis of triazole-based RGD integrin ligands as non-peptide molecular imaging probes for angiogenesis
  32. Differential u PAR recruitment in caveolar‐lipid rafts by GM 1 and GM 3 gangliosides regulates endothelial progenitor cells angiogenesis
  33. Safety Testing of Blue Vital Dyes Using Cell Culture Models