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  1. Predictive and patient-monitoring biomarkers: precision in the management of colorectal cancer

    Article • Biomarkers in Medicine, April 2020, Future Medicine

    Dr Demosthenes E. Ziogas

  2. Bulk and Single-Cell Next-Generation Sequencing: Individualizing Treatment for Colorectal Cancer

    Article • Cancers, November 2019, MDPI AG

    Dr Demosthenes E. Ziogas

  3. Genomic and transcriptional heterogeneity-based precision in personalized treatment for breast cancer

    Article • Personalized Medicine, September 2019, Future Medicine

    Dr Demosthenes E. Ziogas

  4. Drug resistance: origins, evolution and characterization of genomic clones and the tumor ecosystem to optimize precise individualized therapy

    Article • Drug Discovery Today, June 2019, Elsevier

    Dr Demosthenes E. Ziogas

  5. Precision oncology in patients with nonmetastatic disease: emerging reality or illusion

    Article • Future Oncology, June 2019, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  6. Dynamic genome and transcriptional network-based biomarkers and drugs: precision in breast cancer therapy

    Article • Medicinal Research Reviews, November 2018, Wiley

    Dr Demosthenes E. Ziogas

  7. Following the introduction of novel technologies it's time to transfer them to bedside

    Article • Personalized Medicine, November 2018, Future Medicine

    Dr Demosthenes E. Ziogas

  8. Discovering novel valid biomarkers and drugs in patient-centric genomic trials: the new epoch of precision surgical oncology

    Article • Drug Discovery Today, November 2018, Elsevier

    Dr Demosthenes E. Ziogas

  9. Early solid tumor diagnosis through next-generation sequencing of cell-free DNA

    Article • Biomarkers in Medicine, October 2018, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  10. Breakthrough cancer genome analysis in time and space: novel oncotargets and early drug development

    Article • Pharmacogenomics, October 2018, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  11. Breast cancer genome analysis in time and space: biomarker development strategy

    Article • Biomarkers in Medicine, June 2018, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  12. Novel technologies for breast cancer

    Article • Future Oncology, May 2018, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  13. Prediction of pancreatic cancer risk and therapeutic response with next-generation sequencing

    Article • Biomarkers in Medicine, January 2018, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  14. Next-generation sequencing: from conventional applications to breakthrough genomic analyses and precision oncology

    Article • Expert Review of Medical Devices, December 2017, Taylor & Francis

    Dr Demosthenes E. Ziogas, Prof. Dimitrios H. Roukos

  15. Molecular landscape of pancreatic cancer: challenges and clinical implications

    Article • Future Oncology, December 2017, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  16. Advances in HCC

    Article • Future Oncology, August 2017, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  17. Genomic heterogeneity: next-generation sequencing enables biomarker identification for hepatocellular carcinoma

    Article • Biomarkers in Medicine, July 2017, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  18. Novel translational therapeutic strategy by sequencing primary liver cancer genomes

    Article • Future Oncology, May 2017, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  19. Patient-centric research transforms medicine from an inexact science into precision medicine.

    Article • International Journal of Molecular Sciences, January 2017, MDPI AG

    Dr Demosthenes E. Ziogas, Dr William C Cho

  20. Understanding etiopathogenesis on the basis of large-scale translational research studies.

    Article • Future Oncology, January 2017, Future Medicine

    Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas

  21. How intratumor heterogeneity can surpass therapeutic resistance

    Article • Biomarkers in Medicine, July 2016, Future Medicine

    Dr Demosthenes E. Ziogas

  22. Personalized medicine for GI Cancers

    Article • Expert Review of Gastroenterology & Hepatology, May 2016, Taylor & Francis

    Dr Demosthenes E. Ziogas

  23. Palbociclib: an approval at last for HER2-negative breast cancer

    Article • Future Oncology, May 2016, Future Medicine

    Dr Demosthenes E. Ziogas

  24. The current status of breast cancer advances.

    Article • Breast Cancer Management, March 2014, Future Medicine

    Dr Demosthenes E. Ziogas

  25. Novel Next-Generation Sequencing and Networks-Based Therapeutic Targets: Realistic and More Effective Drug Design and Discovery

    Article • Current Pharmaceutical Design, January 2014, Bentham Science Publishers

    Dr Aris Bechlioulis, Prof. Dimitrios H. Roukos, Dr Demosthenes E. Ziogas, Professor Katerina K Naka

  26. Clinical applications of research in gynecogeal cancers

    Article • Current Opinion in Obstetrics & Gynecology, February 2013, Wolters Kluwer Health

    Dr Demosthenes E. Ziogas

  27. Innovative therapies for colrectal cancer

    Article • Expert Review of Gastroenterology & Hepatology, January 2013, Taylor & Francis

    Dr Demosthenes E. Ziogas

  28. Novel advances for colorectal and other cancer types

    Article • Future Oncology, November 2012, Future Medicine

    Dr Demosthenes E. Ziogas

  29. New predictive tools for breast cancer

    Article • Future Oncology, October 2012, Future Medicine

    Dr Demosthenes E. Ziogas

  30. Novel targeted therapies

    Article • Expert Review of Anticancer Therapy, July 2012, Taylor & Francis

    Dr Demosthenes E. Ziogas

  31. Breast cancer is a heterogeneous disease that arises from complex genome–environment interactions.

    Article • Current Oncology, June 2012, MultiMed Inc.

    Dr Demosthenes E. Ziogas

  32. Novel technological systems provide an innovative option for Personalized Oncology

    Article • Future Oncology, June 2012, Future Medicine

    Dr Demosthenes E. Ziogas

  33. The ability of latest DNA sequencing technology to assist Surgical Oncology

    Article • Journal of Surgical Research, April 2012, Elsevier

    Dr Demosthenes E. Ziogas

  34. Explanation and reply to colleauge

    Article • Journal of Burn Care & Research, November 2011, Oxford University Press (OUP)

    Dr Demosthenes E. Ziogas

  35. The most rapidly evolving field of bio-medical research is genomics.

    Article • Expert Review of Molecular Diagnostics, September 2011, Taylor & Francis

    Dr Demosthenes E. Ziogas

  36. Pharmacogenomics for tailoring cardiovascular and anticancer drugs: from genotyping to whole-genome sequencing

    Article • Pharmacogenomics, August 2011, Future Medicine

    Dr Demosthenes E. Ziogas

  37. Omitting Axilla Lymphadenectomy Even by Positive Sentinel Lymph Node: A Change in Breast Cancer Treatment Practice

    Article • Women s Health, July 2011, SAGE Publications

    Dr Demosthenes E. Ziogas

  38. Preventing Familial Breast and Ovarian Cancer: Major Research Advances with Little Implication

    Article • Women s Health, March 2011, SAGE Publications

    Dr Demosthenes E. Ziogas

  39. Tissue Expansion and Latissimus Dorsi Transfer for Arm-Thorax Synechia Reconstruction

    Article • Journal of Burn Care & Research, March 2011, Wolters Kluwer Health

    Dr Demosthenes E. Ziogas

  40. From traditional molecular biology to network oncology

    Article • Future Oncology, February 2011, Future Medicine

    Dr Demosthenes E. Ziogas

  41. New molecular oncology-changing era: prospects and challenges of cancer genome and integrative systems biology

    Article • Expert Review of Anticancer Therapy, January 2011, Taylor & Francis

    Dr Demosthenes E. Ziogas

  42. Laparoscopic restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis and impact of anti-tumor necrosis factor on postoperative outcomes

    Article • Surgical Endoscopy, October 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  43. Colorectal cancer: cetuximab,KRAS,BRAF,PIK3CAmutations and beyond

    Article • Expert Review of Gastroenterology & Hepatology, October 2010, Taylor & Francis

    Dr Demosthenes E. Ziogas

  44. Multigene assays and isolated tumor cells for early breast cancer treatment: time for bionetworks

    Article • Expert Review of Anticancer Therapy, August 2010, Taylor & Francis

    Dr Demosthenes E. Ziogas

  45. From evidence to a day-to-day laparoscopic colectomy

    Article • Surgical Endoscopy, July 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  46. Quality Control in Laparoscopic Gastrectomy for Gastric Cancer—Measurement of Nodes Harvested?

    Article • Annals of Surgical Oncology, May 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  47. Mastectomy vs Breast-Conserving Surgery: An Old Dilemma Comes Again for Early Breast Cancer

    Article • Annals of Surgical Oncology, May 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  48. Chemoradiotherapy in Adenocarcinoma of the Stomach or Esophagus

    Article • Annals of Surgical Oncology, March 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  49. Laparoscopic total gastrectomy: further progress in gastric cancer

    Article • Surgical Endoscopy, February 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  50. Laparoscopic low vs. high anterior resection for rectal cancer

    Article • Surgical Endoscopy, February 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  51. Laparoscopic surgery for rectal cancer: the standard of care?

    Article • Surgical Endoscopy, February 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  52. From tumor size andHER2status to systems oncology for very early breast cancer treatment

    Article • Expert Review of Anticancer Therapy, February 2010, Taylor & Francis

    Dr Demosthenes E. Ziogas

  53. Moving from Lymph Node Metastasis in Gastric Cancer to Biological Markers

    Article • World Journal of Surgery, January 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  54. Laparoscopic and Robotic Rectal Cancer Resection: Expectations for Improving Oncological Outcomes

    Article • Annals of Surgery, January 2010, Wolters Kluwer Health

    Dr Demosthenes E. Ziogas

  55. Open versus laparoscopic versus robotic gastrectomy for cancer: need for comparative-effectiveness quality

    Article • Surgical Endoscopy, January 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  56. Outweighing the benefits and weakness of endoscopic submucosal dissection for early gastric cancer in the west

    Article • Surgical Endoscopy, January 2010, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  57. A literature review about how to save a free flap in breast surgery reconstruction

    Article • Microsurgery, January 2010, Wiley

    Dr Demosthenes E. Ziogas

  58. Follow-Up for Gastric Cancer: How Extensive and Intensive Should It Be?

    Article • Annals of Surgical Oncology, December 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  59. Micrometastatic Sentinel Lymph Node Disease: Do Patients Benefit or Suffer Harm from Axillary Lymph Node Dissection?

    Article • Annals of Surgical Oncology, November 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  60. Caution in Adding Bevacizumab in the Adjuvant Treatment of Breast Cancer

    Article • Annals of Surgical Oncology, November 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  61. Limitations of Isolated Tumor Cells in Gastric Cancer: Heterogeneity Requests Systems Biology Approaches Towards Personalized Medicine

    Article • Annals of Surgical Oncology, October 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  62. Node Micrometastases Detection After Neoadjuvant Chemotherapy in Breast Cancer: Is It of Clinical Value?

    Article • Annals of Surgical Oncology, October 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  63. Searching for a Cutoff Value for Lymph Nodes Retrieved as a Quality Control of Surgery and Pathology in Colon Cancer

    Article • Annals of Surgical Oncology, October 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  64. Nipple-Sparing Mastectomy: Overcoming Oncological Outcomes Challenges

    Article • Annals of Surgical Oncology, September 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  65. Magnetic Resonance Imaging and Potential Impact on Extent of Surgery in Breast Cancer

    Article • Annals of Surgical Oncology, August 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  66. CDH1 Testing: Can it Predict the Prophylactic or Therapeutic Nature of Total Gastrectomy in Hereditary Diffuse Gastric Cancer?

    Article • Annals of Surgical Oncology, July 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  67. Robotic versus laparoscopic gastrectomy

    Article • Surgical Endoscopy, July 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  68. Isolated Tumor Cells in Sentinel Lymph Node and Clinical Implications for Early Breast Cancer

    Article • Annals of Surgical Oncology, June 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  69. Totally Laparoscopic Gastrectomy: A Reality for USA and Europe?

    Article • Annals of Surgical Oncology, June 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  70. Beyond quality-of-life improvement: how robotic surgery for low anterior resection with total mesorectal excision also may improve oncologic outcomes

    Article • Surgical Endoscopy, May 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  71. The Decisive Role of Surgeon’s Experience in Short-Term and Long-Term Oncological Outcomes and Quality of Life in Gastric Cancer

    Article • Annals of Surgical Oncology, May 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  72. Local Excision for Rectal Cancer—Safety and Efficacy Challenges

    Article • Annals of Surgical Oncology, May 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  73. Laparoscopic gastrectomy for organ-confined cancer: a reality in the west?

    Article • Surgical Endoscopy, May 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  74. Robotic D2 surgery for gastric cancer

    Article • Surgical Endoscopy, May 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  75. Epigenetics in Gastric Cancer: Challenges for Clinical Implications

    Article • Annals of Surgical Oncology, May 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  76. Progress and Limitations of Surgery in Improving Outcomes of Esophagogastric Junction Cancer

    Article • Annals of Surgical Oncology, April 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  77. Laparoscopic Colectomy Survival Benefit for Colon Cancer: Is Evidence From a Randomized Trial True?

    Article • Annals of Surgery, April 2009, Wolters Kluwer Health

    Dr Demosthenes E. Ziogas

  78. Genetics and Personal Genomics for Personalized Breast Cancer Surgery: Progress and Challenges in Research and Clinical Practice

    Article • Annals of Surgical Oncology, March 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  79. Breast-Conserving Surgery in Asian Women: Benefits and Potential Harm

    Article • World Journal of Surgery, March 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  80. Limitations of “Classic” Risk Factors to Predict Neoadjuvant Chemotherapy Response for Operable Breast Cancer

    Article • World Journal of Surgery, March 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  81. Neoadjuvant Chemotherapy for Breast Cancer: Does Pretreatment Axillary Nodal Staging Improve Decision Making?

    Article • Annals of Surgical Oncology, February 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  82. Radiation burden of patients undergoing endovascular abdominal aortic aneurysm repair

    Article • Journal of Vascular Surgery, February 2009, Elsevier

    Dr Demosthenes E. Ziogas

  83. Challenges in Developing Robust Genetic Markers and Targets to Predict and Prevent Distant and Peritoneal Recurrence in Gastric Cancer

    Article • Annals of Surgical Oncology, January 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  84. Is There a Role for Surgery in Recurrent Gastric Cancer

    Article • Annals of Surgical Oncology, January 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  85. Stage IV Breast Cancer: Is Surgical Resection of Clinical Utility?

    Article • Annals of Surgical Oncology, January 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  86. Exploring the role of BRCA1, BRCA2 and RAD51 as biomarkers for breast cancer

    Article • Radiotherapy and Oncology, January 2009, Elsevier

    Dr Demosthenes E. Ziogas

  87. Highly elevated serum levels of CA 19-9 in choledocholithiasis: a case report

    Article • Cases Journal, January 2009, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  88. Predicting and Preventing Positive Surgical Margins and Local Failures in Breast-Conserving Surgery

    Article • Annals of Surgical Oncology, December 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  89. Exploring Clinical Implications of Mechanisms for Breast Cancer Local Recurrence

    Article • Annals of Surgical Oncology, September 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  90. Screening for or Prevention of Local Ipsilateral Recurrence and Contralateral Breast Cancer After Breast-Conserving Surgery?

    Article • Annals of Surgical Oncology, July 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  91. Human Genetic and Structural Genomic Variation: Would Genome-Wide Association Studies Be the Solution for Cancer Complexity Like Alexander the Great for the “Gordian Knot”?

    Article • Annals of Surgical Oncology, July 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  92. Continuing Debate on D2 Lymphadenectomy for Gastric Cancer

    Article • World Journal of Surgery, June 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  93. HER2 and Trastuzumab: Impact of a New Standard Agent on Local Control and Surgery for Breast Cancer

    Article • Annals of Surgical Oncology, June 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  94. Lessons from Laparoscopic Gastrectomy: Preventing Surgical Complications

    Article • Annals of Surgical Oncology, May 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  95. Identifying and Preventing High-risk Gastric Cancer Individuals With CDH1 Mutations

    Article • Annals of Surgery, April 2008, Wolters Kluwer Health

    Dr Demosthenes E. Ziogas

  96. Benefits, Limitations, and Harm of Local Excision for Rectal Cancer

    Article • Annals of Surgical Oncology, March 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  97. Targeting VEGF, EGFR, and Other Interacting Pathways for Gastric Cancer—Promises and Reality

    Article • Annals of Surgical Oncology, March 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  98. Robotic surgery for rectal cancer: may it improve also survival?

    Article • Surgical Endoscopy, March 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  99. Lumpectomy and Partial Breast Irradiation - Risks and Benefits for Early Breast Cancer

    Article • Annals of Surgical Oncology, February 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  100. EGFR as a Prognostic Marker for Gastric Cancer

    Article • World Journal of Surgery, January 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  101. Controversy in the Treatment of Gastric Cancer

    Article • Annals of Surgical Oncology, January 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  102. Prophylactic Surgery in the Complex Decision-Making Management of BRCA Mutation Carriers

    Article • Annals of Surgical Oncology, January 2008, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  103. Intestinal obstruction due to an anomalous congenital band

    Article • Saudi Journal of Gastroenterology, January 2008, Medknow

    Dr Demosthenes E. Ziogas

  104. Outcomes of breast cancer patients with and without BRCA1/2 mutations

    Article • International Journal of Cancer, December 2007, Wiley

    Dr Demosthenes E. Ziogas

  105. Advances in Laparoscopic Gastrectomy Expand Clinical Use

    Article • Annals of Surgical Oncology, December 2007, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  106. Breast Conservation Therapy: Multiple Reexcisions or Subcutaneous and Nipple-Sparing Mastectomy?

    Article • Annals of Surgical Oncology, December 2007, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  107. The Importance of Surgical Margin Control in Breast-Conserving Therapy

    Article • Annals of Surgical Oncology, October 2007, Springer Science + Business Media

    Dr Demosthenes E. Ziogas

  108. Lymphadenectomy in Surgical Oncology

    Article • Annals of Surgical Oncology, October 2007, Springer Science + Business Media

    Dr Demosthenes E. Ziogas