All Stories

  1. Reply to: a quantitative trait locus for reduced microglial APOE expression associates with reduced cerebral amyloid angiopathy

    Article • Nature Genetics, January 2026, Springer Science + Business Media

    Dr David W Fardo

  2. A bioinformatic survey of RNA isoform diversity and expression across 9 GTEx tissues using long-read sequencing data

    Article • BMC Genomics, December 2025, Springer Science + Business Media

    Dr David W Fardo

  3. Genome annotations matter: characterizing Ensembl hg38 annotations from 2014 to 2023

    Article • BMC Genomics, December 2025, Springer Science + Business Media

    Dr David W Fardo

  4. Genetic association analyses of cognitive performance across multi-ancestry older adults: Application of Tobit models

    Article • Journal of Alzheimer’s Disease, October 2025, SAGE Publications

    Dr David W Fardo

  5. Systematic review and meta-analysis of bulk RNAseq studies in human Alzheimer’s disease brain tissue

    Article • November 2024, openRxiv

    Dr David W Fardo

  6. Medicare medication therapy Management: Beneficiary characteristics and utilization patterns in a national CMS Medicare fee-for-service sample (2013 to 2016)

    Article • Journal of the American Pharmacists Association, September 2024, Elsevier

    Dr David W Fardo

  7. Limbic-predominant age-related TDP-43 encephalopathy (LATE-NC): Co-pathologies and genetic risk factors provide clues about pathogenesis

    Article • Journal of Neuropathology & Experimental Neurology, April 2024, Oxford University Press (OUP)

    Dr David W Fardo

  8. Novel multi-omics deconfounding variational autoencoders can obtain meaningful disease subtyping

    Article • February 2024, openRxiv

    Dr David W Fardo

  9. Atorvastatin rescues hyperhomocysteinemia-induced cognitive deficits and neuroinflammatory gene changes

    Article • Journal of Neuroinflammation, September 2023, Springer Science + Business Media

    Dr David W Fardo

  10. A neuropathologic feature of brain aging: multi-lumen vascular profiles

    Article • Acta Neuropathologica Communications, August 2023, Springer Science + Business Media

    Dr David W Fardo

  11. Different cohort, disparate results: Selection bias is a key factor in autopsy cohorts

    Article • Alzheimer s & Dementia, August 2023, Wiley

    Dr David W Fardo

  12. LATE-NC risk alleles (in TMEM106B, GRN, and ABCC9 genes) among persons with African ancestry

    Article • Journal of Neuropathology & Experimental Neurology, August 2023, Oxford University Press (OUP)

    Dr David W Fardo

  13. Urinary Incontinence in a Community-Based Autopsy Cohort Is Associated with Limbic Predominant Age-Related TDP-43 Encephalopathy Neuropathologic Changes

    Article • Journal of Alzheimer’s Disease, June 2023, IOS Press

    Dr David W Fardo

  14. Associations of potential ADRD plasma biomarkers in cognitively normal volunteers

    Article • Alzheimer s & Dementia, February 2023, Wiley

    Dr David W Fardo

  15. Estimating random effects in a finite Markov chain with absorbing states: Application to cognitive data

    Article • Statistica Neerlandica, February 2023, Wiley

    Dr David W Fardo

  16. Genome-wide association study of multiple neuropathology endophenotypes identifies novel risk loci and provides insights into known Alzheimer’s risk loci

    Article • December 2022, openRxiv

    Dr David W Fardo

  17. Evaluation of pathologies associated with hyperhomocysteinemia in human autopsy brain tissue

    Article • Alzheimer s & Dementia, December 2022, Wiley

    Dr David W Fardo

  18. The association of gabapentin initiation and neurocognitive changes in older adults with normal cognition

    Article • Frontiers in Pharmacology, November 2022, Frontiers

    Dr David W Fardo

  19. Multiple gene variants linked to Alzheimer's-type clinical dementia via GWAS are also associated with non-Alzheimer's neuropathologic entities

    Article • Neurobiology of Disease, November 2022, Elsevier

    Dr David W Fardo

  20. Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease

    Article • Brain, May 2022, Oxford University Press (OUP)

    Dr David W Fardo

  21. Manifestations of Alzheimer’s disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90

    Article • Scientific Reports, April 2022, Springer Science + Business Media

    Dr David W Fardo

  22. Limbic-Predominant Age-Related TDP-43 Encephalopathy

    Article • Neurology, April 2022, Wolters Kluwer Health

    Dr David W Fardo

  23. New insights into the genetic etiology of Alzheimer’s disease and related dementias

    Article • Nature Genetics, April 2022, Springer Science + Business Media

    Dr Edna Grünblatt, Jari Lahti, Dr David W Fardo

  24. Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer’s disease-associated genes: DTNB and DLG2

    Article • Molecular Psychiatry, March 2022, Springer Science + Business Media

    Dr David W Fardo

  25. Association between WWOX/MAF variants and dementia-related neuropathologic endophenotypes

    Article • Neurobiology of Aging, March 2022, Elsevier

    Dr David W Fardo

  26. Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue

    Article • Alzheimer s & Dementia Translational Research & Clinical Interventions, January 2022, Wiley

    Dr David W Fardo

  27. Type 2 Diabetes and association with neuropathological changes and domain specific cognitive decline

    Article • Alzheimer s & Dementia, December 2021, Wiley

    Dr David W Fardo

  28. Analysis of genes (TMEM106B, GRN, ABCC9, KCNMB2, and APOE) implicated in risk for LATE-NC and hippocampal sclerosis provides pathogenetic insights: a retrospective genetic association study

    Article • Acta Neuropathologica Communications, September 2021, Springer Science + Business Media

    Dr David W Fardo

  29. Inflammatory Pathways Are Impaired in Alzheimer Disease and Differentially Associated With Apolipoprotein E Status

    Article • Journal of Neuropathology & Experimental Neurology, September 2021, Oxford University Press (OUP)

    Dr David W Fardo

  30. Predictors of chronic opioid therapy in Medicaid beneficiaries with HIV who initiated antiretroviral therapy

    Article • Scientific Reports, July 2021, Springer Science + Business Media

    Dr David W Fardo

  31. Four Common Late-Life Cognitive Trajectories Patterns Associate with Replicable Underlying Neuropathologies

    Article • Journal of Alzheimer’s Disease, July 2021, IOS Press

    Dr. Shama D Karanth, Dr David W Fardo

  32. Identification of novel and rare variants associated with handgrip strength using whole genome sequence data from the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program

    Article • PLOS One, July 2021, PLOS

    Dr David W Fardo

  33. Analysis of Genetic Variants Associated with Levels of Immune Modulating Proteins for Impact on Alzheimer’s Disease Risk Reveal a Potential Role for SIGLEC14

    Article • Genes, June 2021, MDPI AG

    Dr David W Fardo

  34. Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer’s disease-associated genes: DTNB and DLG2

    Article • June 2021, openRxiv

    Dr David W Fardo

  35. A New Functional F-Statistic for Gene-Based Inference Involving Multiple Phenotypes

    Article • May 2021, openRxiv

    Dr David W Fardo

  36. A Highly Predictive MicroRNA Panel for Determining Delayed Cerebral Vasospasm Risk Following Aneurysmal Subarachnoid Hemorrhage

    Article • Frontiers in Molecular Biosciences, May 2021, Frontiers

    Dr David W Fardo

  37. Age and sex are associated with the plasma lipidome: findings from the GOLDN study

    Article • Lipids in Health and Disease, April 2021, Springer Science + Business Media

    Dr David W Fardo

  38. Reduced rank multinomial logistic regression in Markov chains with application to cognitive data

    Article • Statistics in Medicine, March 2021, Wiley

    Dr David W Fardo

  39. Longitudinal cognitive performance of Alzheimer's disease neuropathological subtypes

    Article • Alzheimer s & Dementia Translational Research & Clinical Interventions, January 2021, Wiley

    Dr David W Fardo

  40. Brain arteriolosclerosis

    Article • Acta Neuropathologica, October 2020, Springer Science + Business Media

    Dr David W Fardo

  41. Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

    Article • JAMA Neurology, October 2020, American Medical Association (AMA)

    Dr David W Fardo

  42. Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy

    Article • Acta Neuropathologica, August 2020, Springer Science + Business Media

    Dr David W Fardo

  43. Quantitative phenotype scan statistic (QPSS) reveals rare variant associations with Alzheimer’s disease endophenotypes

    Article • BMC Medical Genetics, May 2020, Springer Science + Business Media

    Dr David W Fardo

  44. The MUC6/AP2A2 Locus and Its Relevance to Alzheimer’s Disease: A Review

    Article • Journal of Neuropathology & Experimental Neurology, March 2020, Oxford University Press (OUP)

    Dr David W Fardo

  45. Genetic Variants and Functional Pathways Associated with Resilience to Alzheimer’s Disease

    Article • February 2020, openRxiv

    Dr David W Fardo

  46. Hierarchical Clustering Analyses of Plasma Proteins in Subjects With Cardiovascular Risk Factors Identify Informative Subsets Based on Differential Levels of Angiogenic and Inflammatory Biomarkers

    Article • Frontiers in Neuroscience, February 2020, Frontiers

    Dr David W Fardo

  47. Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene

    Article • Journal of Neuropathology & Experimental Neurology, November 2019, Oxford University Press (OUP)

    Dr David W Fardo

  48. Author Correction: Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

    Article • Nature Genetics, August 2019, Springer Science + Business Media

    Dr David W Fardo

  49. Reply: LATE to the PART-y

    Article • Brain, July 2019, Oxford University Press (OUP)

    Dr David W Fardo

  50. Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy

    Article • Laboratory Investigation, July 2019, Elsevier

    Dr David W Fardo

  51. Erratum

    Article • Brain, May 2019, Oxford University Press (OUP)

    Dr David W Fardo

  52. Evaluation of CD33 as a genetic risk factor for Alzheimer’s disease

    Article • Acta Neuropathologica, April 2019, Springer Science + Business Media

    Dr David W Fardo

  53. Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis

    Article • Journal of Alzheimer’s Disease, March 2019, SAGE Publications

    Dr David W Fardo

  54. Socioemotional selectivity and psychological health in amyotrophic lateral sclerosis patients and caregivers: a longitudinal, dyadic analysis

    Article • Psychology & Health, March 2019, Taylor & Francis

    Dr David W Fardo

  55. Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

    Article • Nature Genetics, February 2019, Springer Science + Business Media

    Dr. Rita Guerreiro, Dr David W Fardo

  56. Translating Alzheimer's disease–associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs

    Article • Neurobiology of Aging, February 2019, Elsevier

    Dr David W Fardo, Professor of Clinical Psychiatry Adrian PREDA, Dr. Raymond Scott Turner

  57. Characterization of Squamous Cell Lung Cancers from Appalachian Kentucky

    Article • Cancer Epidemiology Biomarkers & Prevention, February 2019, American Association for Cancer Research (AACR)

    Dr David W Fardo

  58. Correction: Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups

    Article • Molecular Psychiatry, January 2019, Springer Science + Business Media

    Dr David W Fardo

  59. Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study

    Article • PLOS One, January 2019, PLOS

    Dr David W Fardo

  60. Noninvasive sleep monitoring in large-scale screening of knock-out mice reveals novel sleep-related genes

    Article • January 2019, openRxiv

    Dr David W Fardo

  61. Estimation of multi-state models with missing covariate values based on observed data likelihood

    Article • Communication in Statistics- Theory and Methods, December 2018, Taylor & Francis

    Erin Abner, Dr David W Fardo

  62. Genetic data and cognitively defined late-onset Alzheimer’s disease subgroups

    Article • Molecular Psychiatry, December 2018, Springer Science + Business Media

    Dr David W Fardo

  63. Dichotomous scoring of TDP-43 proteinopathy from specific brain regions in 27 academic research centers: associations with Alzheimer’s disease and cerebrovascular disease pathologies

    Article • Acta Neuropathologica Communications, December 2018, Springer Science + Business Media

    Dr David W Fardo

  64. Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

    Article • Neurobiology of Aging, December 2018, Elsevier

    Dr David W Fardo

  65. Longitudinal data methods for evaluating genome-by-epigenome interactions in families

    Article • BMC Genetics, September 2018, Springer Science + Business Media

    Chanung Wang, Dr David W Fardo

  66. Association analyses of repeated measures on triglyceride and high-density lipoprotein levels: insights from GAW20

    Article • BMC Genetics, September 2018, Springer Science + Business Media

    Dr David W Fardo

  67. GAW20: methods and strategies for the new frontiers of epigenetics and pharmacogenomics

    Article • BMC Proceedings, September 2018, Springer Science + Business Media

    Dr David W Fardo

  68. Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau

    Article • JAMA Neurology, August 2018, American Medical Association (AMA)

    Dr David W Fardo

  69. Genetic data and cognitively-defined late-onset Alzheimer’s disease subgroups

    Article • July 2018, openRxiv

    Dr David W Fardo

  70. Sex-specific genetic predictors of Alzheimer’s disease biomarkers

    Article • Acta Neuropathologica, July 2018, Springer Science + Business Media

    Dr David W Fardo

  71. Visual Arts Education improves self-esteem for persons with dementia and reduces caregiver burden: A randomized controlled trial

    Article • Dementia, April 2018, SAGE Publications

    Ann Tietyen, Dr David W Fardo

  72. Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

    Article • April 2018, openRxiv

    Dr David W Fardo

  73. Genetically elevated high‐density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

    Article • Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring, January 2018, Wiley

    Dr David W Fardo

  74. Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons

    Article • Journal of Neuropathology & Experimental Neurology, November 2017, Oxford University Press (OUP)

    Dr David W Fardo

  75. The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

    Article • Journal of Neuropathology & Experimental Neurology, November 2017, Oxford University Press (OUP)

    Dr David W Fardo

  76. Impact of home visit capacity on genetic association studies of late-onset Alzheimer's disease

    Article • Alzheimer s & Dementia, August 2017, Elsevier

    Dr David W Fardo

  77. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

    Article • Nature Genetics, July 2017, Springer Science + Business Media

    Francesco Panza, Dr. Rita Guerreiro, Dr David W Fardo

  78. Peripheral Inflammation, Apolipoprotein E4 , and Amyloid-β Interact to Induce Cognitive and Cerebrovascular Dysfunction

    Article • ASN NEURO, July 2017, Taylor & Francis

    Dr David W Fardo

  79. Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN , TMEM106B , ABCC9 , and KCNMB2

    Article • Neurobiology of Aging, May 2017, Elsevier

    Dr David W Fardo

  80. Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults

    Article • Aging, April 2017, Impact Journals, LLC

    Dr David W Fardo

  81. CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN /PGRN

    Article • Experimental Gerontology, April 2017, Elsevier

    Dr David W Fardo

  82. Overlapping but distinct TDP‐43 and tau pathologic patterns in aged hippocampi

    Article • Brain Pathology, March 2017, Wiley

    Dr David W Fardo

  83. Outcomes after diagnosis of mild cognitive impairment in a large autopsy series

    Article • Annals of Neurology, March 2017, Wiley

    Dr David W Fardo

  84. Systems biology approach to late‐onset Alzheimer's disease genome‐wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments

    Article • Alzheimer s & Dementia, February 2017, Wiley

    Dr David W Fardo

  85. Multi-state models and missing covariate data: expectation–maximization algorithm for likelihood estimation

    Article • Biostatistics & Epidemiology, January 2017, Taylor & Francis

    Dr David W Fardo

  86. Risk of incident clinical diagnosis of Alzheimer's disease–type dementia attributable to pathology‐confirmed vascular disease

    Article • Alzheimer s & Dementia, December 2016, Wiley

    Dr David W Fardo

  87. Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

    Article • Acta Neuropathologica, November 2016, Springer Science + Business Media

    Dr David W Fardo

  88. On combining family- and population-based sequencing data

    Article • BMC Proceedings, October 2016, Springer Science + Business Media

    Dr David W Fardo

  89. Causal effect estimation in sequencing studies: a Bayesian method to account for confounder adjustment uncertainty

    Article • BMC Proceedings, October 2016, Springer Science + Business Media

    Dr David W Fardo

  90. Comparing performance of non–tree-based and tree-based association mapping methods

    Article • BMC Proceedings, October 2016, Springer Science + Business Media

    Dr David W Fardo

  91. Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology

    Article • Alzheimer s & Dementia, August 2016, Elsevier

    Dr David W Fardo

  92. Automated quality control for genome wide association studies

    Article • F1000Research, July 2016, Faculty of 1000, Ltd.

    Dr David W Fardo

  93. Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals

    Article • Journal of Cerebral Blood Flow & Metabolism, July 2016, SAGE Publications

    Dr David W Fardo

  94. Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease

    Article • Alzheimer s & Dementia, June 2016, Elsevier

    Dr David W Fardo

  95. “New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)

    Article • Journal of Neuropathology & Experimental Neurology, May 2016, Oxford University Press (OUP)

    Dr David W Fardo

  96. The executive prominent/memory prominent spectrum in Alzheimer's disease is highly heritable

    Article • Neurobiology of Aging, May 2016, Elsevier

    Dr David W Fardo

  97. Assessment of the genetic variance of late-onset Alzheimer's disease

    Article • Neurobiology of Aging, May 2016, Elsevier

    Dr David W Fardo

  98. ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target

    Article • Ageing Research Reviews, November 2015, Elsevier

    Dr David W Fardo

  99. Genetics ignite focus on microglial inflammation in Alzheimer’s disease

    Article • Molecular Neurodegeneration, October 2015, Springer Science + Business Media

    Dr David W Fardo

  100. Openness to Change: Experiential and Demographic Components of Change in Local Health Department Leaders

    Article • Frontiers in Public Health, September 2015, Frontiers

    Dr David W Fardo

  101. Genetics and non-syndromic facial growth

    Article • Journal of Pediatric Genetics, July 2015, IOS Press

    Dr David W Fardo

  102. Novel humanABCC9/SUR2brain-expressed transcripts and an eQTL relevant to hippocampal sclerosis of aging

    Article • Journal of Neurochemistry, July 2015, Wiley

    Dr David W Fardo

  103. Self-reported memory complaints: A comparison of demented and unimpaired outcomes

    Article • Alzheimer s & Dementia, July 2015, Elsevier

    Dr David W Fardo

  104. Genetic differences between symptomatic and asymptomatic persons with Alzheimer's disease neuropathologic change

    Article • Alzheimer s & Dementia, July 2015, Elsevier

    Dr David W Fardo

  105. Integrating human protein-protein interaction network with results from gwas in whites and african-americans identifies common genes underlying late-onset Alzheimer’s disease

    Article • Alzheimer s & Dementia, July 2015, Elsevier

    Dr David W Fardo

  106. A Summary Score for the Framingham Heart Study Neuropsychological Battery

    Article • Journal of Aging and Health, March 2015, SAGE Publications

    Dr David W Fardo

  107. Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia

    Article • Human Molecular Genetics, March 2015, Oxford University Press (OUP)

    Dr David W Fardo

  108. Should They Stay or Should They Go? Leader Duration and Financial Performance in Local Health Departments

    Article • Journal of Public Health Management and Practice, January 2015, Wolters Kluwer Health

    Dr David W Fardo

  109. Reassessment of Risk Genotypes (GRN,TMEM106B, andABCC9Variants) Associated With Hippocampal Sclerosis of Aging Pathology

    Article • Journal of Neuropathology & Experimental Neurology, January 2015, Oxford University Press (OUP)

    Dr David W Fardo

  110. Assessing the Discriminant Ability, Reliability, and Comparability of Multiple Short Forms of the Boston Naming Test in an Alzheimer's Disease Center Cohort

    Article • Dementia and Geriatric Cognitive Disorders, January 2015, Karger Publishers

    Dr David W Fardo

  111. Analysis of sleep traits in knockout mice from the large-scale KOMP2 population using a non-invasive, high-throughput piezoelectric system

    Article • BMC Bioinformatics, January 2015, Springer Science + Business Media

    Dr David W Fardo

  112. Impact of Population Stratification on Family-Based Association in an Admixed Population

    Article • International Journal of Genomics, January 2015, Hindawi Publishing Corporation

    Dr David W Fardo

  113. An Ecological Systems Examination of Elder Abuse: A Week in the Life of Adult Protective Services

    Article • Journal of Elder Abuse & Neglect, October 2014, Taylor & Francis

    Dr David W Fardo

  114. Longitudinal Trajectories of Cholesterol from Midlife through Late Life according to Apolipoprotein E Allele Status

    Article • International Journal of Environmental Research and Public Health, October 2014, MDPI AG

    Dr David W Fardo

  115. Self-reported memory complaints: Implications from a longitudinal cohort with autopsies

    Article • Neurology, September 2014, Wolters Kluwer Health

    Dr David W Fardo

  116. Effects of Alcohol Consumption on Cognition and Regional Brain Volumes Among Older Adults

    Article • American Journal of Alzheimer s Disease & Other Dementias®, September 2014, SAGE Publications

    Dr David W Fardo

  117. Governance Practices and Performance in US Academic Medical Centers

    Article • American Journal of Medical Quality, August 2014, SAGE Publications

    Dr David W Fardo

  118. Complex Pedigrees in the Sequencing Era: To Track Transmissions or Decorrelate?

    Article • Genetic Epidemiology, August 2014, Wiley

    Dr David W Fardo

  119. Genetic Analysis Workshop 18: Methods and strategies for analyzing human sequence and phenotype data in members of extended pedigrees

    Article • BMC Proceedings, June 2014, Springer Science + Business Media

    Dr Phillip Melton, Dr David W Fardo

  120. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

    Article • Acta Neuropathologica, April 2014, Springer Science + Business Media

    Dr David W Fardo

  121. Comparison of BMI, AHI, and Apolipoprotein E ε4 (APOE-ε4) Alleles among Sleep Apnea Patients with Different Skeletal Classifications

    Article • Journal of Clinical Sleep Medicine, April 2014, American Academy of Sleep Medicine (AASM)

    Dr David W Fardo

  122. Low Plasma Leptin in Cognitively Impaired ADNI Subjects: Gender Differences and Diagnostic and Therapeutic Potential

    Article • Current Alzheimer Research, March 2014, Bentham Science Publishers

    Professor George Perry, Dr David W Fardo

  123. Genetics of PICALM Expression and Alzheimer's Disease

    Article • PLOS One, March 2014, PLOS

    Dr David W Fardo

  124. Assessment of appalachian region pediatric hearing healthcare disparities and delays

    Article • The Laryngoscope, February 2014, Wiley

    Dr David W Fardo

  125. Delays in Diagnosis of Congenital Hearing Loss in Rural Children

    Article • The Journal of Pediatrics, February 2014, Elsevier

    Dr David W Fardo

  126. An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform

    Article • Molecular Neurodegeneration, January 2014, Springer Science + Business Media

    Dr David W Fardo

  127. A 2-step penalized regression method for family-based next-generation sequencing association studies

    Article • BMC Proceedings, January 2014, Springer Science + Business Media

    Dr David W Fardo

  128. Modeling of multivariate longitudinal phenotypes in family genetic studies with Bayesian multiplicity adjustment

    Article • BMC Proceedings, January 2014, Springer Science + Business Media

    Dr David W Fardo

  129. On family-based genome-wide association studies with large pedigrees: observations and recommendations

    Article • BMC Proceedings, January 2014, Springer Science + Business Media

    Dr David W Fardo

  130. Using Mendelian inheritance errors as quality control criteria in whole genome sequencing data set

    Article • BMC Proceedings, January 2014, Springer Science + Business Media

    Dr David W Fardo

  131. Self-Reported Head Injury and Risk of Late-Life Impairment and AD Pathology in an AD Center Cohort

    Article • Dementia and Geriatric Cognitive Disorders, December 2013, Karger Publishers

    Dr David W Fardo

  132. ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status

    Article • Neuroscience Letters, November 2013, Elsevier

    Dr David W Fardo

  133. The Relationship Between Midlife and Late Life Alcohol Consumption, APOE e4 and the Decline in Learning and Memory Among Older Adults

    Article • Alcohol and Alcoholism, September 2013, Oxford University Press (OUP)

    Dr David W Fardo

  134. CD33 Alzheimer's Risk-Altering Polymorphism, CD33 Expression, and Exon 2 Splicing

    Article • Journal of Neuroscience, August 2013, Society for Neuroscience

    Dr David W Fardo

  135. Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

    Article • Acta Neuropathologica, July 2013, Springer Science + Business Media

    Dr David W Fardo

  136. Vascular neuropathology in dementia patients receiving antipsychotic therapy

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr David W Fardo

  137. Vascular disease, vascular risk factors and risk of late-onset Alzheimer's disease: Mendelian randomization analyses in the combined ADGC dataset

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr David W Fardo

  138. Early-to mid-life formal training in music is associated with improved late-life semantic and episodic memory among cognitively normal older adults

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr David W Fardo

  139. Clinical correlates of hippocampal sclerosis of aging: The University of Kentucky experience

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr David W Fardo

  140. Self-reported head injury and risk of cognitive impairment and Alzheimer's-type pathology in a longitudinal Alzheimer’s disease center cohort

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr David W Fardo

  141. Genome-wide SNP analysis finds executive-prominent late-onset Alzheimer's disease is highly heritable

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr David W Fardo

  142. GWAS of the joint ADGC data set identifies novel common variants associated with late-onset Alzheimer's disease

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr David W Fardo

  143. APOE-ε2 and APOE-ε4 Correlate With Increased Amyloid Accumulation in Cerebral Vasculature

    Article • Journal of Neuropathology & Experimental Neurology, July 2013, Oxford University Press (OUP)

    Dr David W Fardo

  144. Self-reported memory decline predicts mild cognitive impairment and dementia

    Article • Alzheimer s & Dementia, July 2013, Elsevier

    Dr David W Fardo

  145. Adjusting for Mortality when Identifying Risk Factors for Transitions to Mild Cognitive Impairment and Dementia

    Article • Journal of Alzheimer’s Disease, May 2013, SAGE Publications

    Dr David W Fardo

  146. Board Oversight of Patient Care Quality in Large Nonprofit Health Systems

    Article • American Journal of Medical Quality, May 2013, SAGE Publications

    Dr David W Fardo

  147. Levels of Soluble Apolipoprotein E/Amyloid-  (A ) Complex Are Reduced and Oligomeric A  Increased with APOE4 and Alzheimer Disease in a Transgenic Mouse Model and Human Samples

    Article • Journal of Biological Chemistry, January 2013, American Society for Biochemistry & Molecular Biology (ASBMB)

    Dr David W Fardo

  148. Generic antiepileptic drug prescribing: A cross-sectional study

    Article • Epilepsy & Behavior, January 2013, Elsevier

    Dr David W Fardo

  149. Combining genetic association study designs: a GWAS case study

    Article • Frontiers in Genetics, January 2013, Frontiers

    Dr David W Fardo

  150. Paradoxical Relationship Between the Degree of EGFR Amplification and Outcome in Glioblastomas

    Article • The American Journal of Surgical Pathology, August 2012, Wolters Kluwer Health

    Dr David W Fardo

  151. Effect of gene-environment interactions between APOE-ɛ4 and lifetime alcohol consumption on cognition in older adults

    Article • Alzheimer s & Dementia, July 2012, Elsevier

    Dr David W Fardo

  152. Genetics of Clusterin Isoform Expression and Alzheimer's Disease Risk

    Article • PLOS One, April 2012, PLOS

    Dr David W Fardo

  153. Families or Unrelated: The Evolving Debate in Genetic Association Studies

    Article • Journal of Biometrics & Biostatistics, January 2012, OMICS Publishing Group

    Dr David W Fardo

  154. Mild Cognitive Impairment: Statistical Models of Transition Using Longitudinal Clinical Data

    Article • International Journal of Alzheimer s Disease, January 2012, Hindawi Publishing Corporation

    Dr David W Fardo

  155. Gene-environment interaction testing in family-based association studies with phenotypically ascertained samples: a causal inference approach

    Article • Biostatistics, November 2011, Oxford University Press (OUP)

    Dr David W Fardo

  156. PATHOLOGY

    Article • Neuro-Oncology, October 2011, Oxford University Press (OUP)

    Dr David W Fardo

  157. Evaluation of retention protocols among members of the American Association of Orthodontists in the United States

    Article • American Journal of Orthodontics and Dentofacial Orthopedics, October 2011, Elsevier

    Dr David W Fardo

  158. Race-ethnicity as an effect modifier of the association between HbAlc and mortality in U.S. adults without diagnosed diabetes

    Article • European Journal of Endocrinology, May 2011, Bioscientifica

    Dr David W Fardo

  159. Sclerostin and Dickkopf-1 in Renal Osteodystrophy

    Article • Clinical Journal of the American Society of Nephrology, April 2011, Wolters Kluwer Health

    Dr David W Fardo

  160. Exploration and comparison of methods for combining population- and family-based genetic association using the Genetic Analysis Workshop 17 mini-exome

    Article • BMC Proceedings, January 2011, Springer Science + Business Media

    Dr David W Fardo

  161. On Quality Control Measures in Genome-Wide Association Studies: A Test to Assess the Genotyping Quality of Individual Probands in Family-Based Association Studies and an Application to the HapMap Data

    Article • PLoS Genetics, July 2009, PLOS

    Dr David W Fardo

  162. Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy–Weinberg equilibrium

    Article • European Journal of Human Genetics, June 2009, Nature

    Dr David W Fardo

  163. Predictors of an Accurate Preoperative Sestamibi Scan for Single-Gland Parathyroid Adenomas

    Article • Archives of Surgery, April 2007, American Medical Association (AMA)

    Dr David W Fardo

  164. On dichotomizing phenotypes in family‐based association tests: quantitative phenotypes are not always the optimal choice

    Article • Genetic Epidemiology, March 2007, Wiley

    Dr Juan Carlos Celedon, Dr David W Fardo

  165. Guest Commentary by Dr. David H. Johnson

    Article • January 2005, American Psychological Association (APA)

    Dr David W Fardo