All Stories

  1. Phase 3 randomized clinical trials of simufilam in mild-to-moderate Alzheimer’s disease
  2. The financial consequences of undiagnosed memory disorders
  3. Resveratrol Attenuates CSF Markers of Neurodegeneration and Neuroinflammation in Individuals with Alzheimer’s Disease
  4. Aging as a target for the prevention and treatment of Alzheimer’s disease
  5. Screening for Cognitive Decline in Isolated/Idiopathic REM Sleep Behavior Disorder
  6. Resveratrol differentially affects MMP‐9 release from neurons and glia; implications for therapeutic efficacy
  7. Effects of the active amyloid beta immunotherapy CAD106 on PET measurements of amyloid plaque deposition in cognitively unimpaired APOE ε4 homozygotes
  8. Two Phase 3 Trials of Gantenerumab in Early Alzheimer’s Disease
  9. The Sporadic Early‐onset Alzheimer's Disease Signature Of Atrophy: Preliminary Findings From The Longitudinal Early‐onset Alzheimer's Disease Study (LEADS) Cohort
  10. Pathogenic variants in the Longitudinal Early‐onset Alzheimer's Disease Study cohort
  11. An explainable machine learning model of cognitive decline derived from speech
  12. Amyloid and tau‐PET in early‐onset AD: Baseline data from the Longitudinal Early‐onset Alzheimer's Disease Study (LEADS)
  13. Influence of amyloid and diagnostic syndrome on non‐traditional memory scores in early‐onset Alzheimer's disease
  14. A blood biomarker test for brain amyloid impacts the clinical evaluation of cognitive impairment
  15. Sex and APOE ε4 carrier effects on atrophy, amyloid PET, and tau PET burden in early‐onset Alzheimer's disease
  16. Cerebrospinal fluid biomarkers in the Longitudinal Early‐onset Alzheimer's Disease Study
  17. White matter hyperintensities are higher among early‐onset Alzheimer's disease participants than their cognitively normal and early‐onset nonAD peers: Longitudinal Early‐onset Alzheimer's Disease Study (LEADS)
  18. Baseline neuropsychiatric symptoms and psychotropic medication use midway through data collection of the Longitudinal Early‐Onset Alzheimer's Disease Study (LEADS) cohort
  19. Profiling baseline performance on the Longitudinal Early‐Onset Alzheimer's Disease Study (LEADS) cohort near the midpoint of data collection
  20. Learning slopes in early‐onset Alzheimer's disease
  21. Matrix disequilibrium in Alzheimer’s disease and conditions that increase Alzheimer’s disease risk
  22. Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease
  23. CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice
  24. Inhibition of discoidin domain receptor (DDR)-1 with nilotinib induces autophagy and reduces inflammation and vascular fibrosis in Alzheimer’s disease
  25. Increasing access to cognitive screening in the elderly: Applying natural language processing methods to speech collected over the telephone
  26. CCR5 deficiency normalizes TIMP levels, working memory, and gamma oscillation power in APOE4 targeted replacement mice
  27. Amyloid-Related Imaging Abnormalities With Anti-amyloid Antibodies for the Treatment of Dementia Due to Alzheimer's Disease
  28. Corrigendum: A 5-min Cognitive Task With Deep Learning Accurately Detects Early Alzheimer's Disease
  29. Class-Based Antiretroviral Exposure and Cognition Among Women Living with HIV
  30. Safety, target engagement, and biomarker effects of bosutinib in dementia with Lewy bodies
  31. Spatial inhibition of return is impaired in mild cognitive impairment and mild Alzheimer’s disease
  32. Low CD4 nadir exacerbates the impacts of APOE ε4 on functional connectivity and memory in adults with HIV
  33. Research Attitudes Questionnaire scores predict Alzheimer’s disease clinical trial dropout
  34. Nilotinib Improves Bioenergetic Profiling in Brain Astroglia in the 3xTg Mouse Model of Alzheimer’s Disease
  35. Acceptability of collecting speech samples from the elderly via the telephone
  36. A 5-min Cognitive Task With Deep Learning Accurately Detects Early Alzheimer's Disease
  37. Potential New Approaches for Diagnosis of Alzheimer's Disease and Related Dementias
  38. Nilotinib Effects on Safety, Tolerability, and Biomarkers in Alzheimer's Disease
  39. Spatial inhibition of return is impaired in mild cognitive impairment and mild Alzheimer’s disease
  40. Effect of AZD0530 on Cerebral Metabolic Decline in Alzheimer Disease
  41. Cancer-Related Cognitive Outcomes Among Older Breast Cancer Survivors in the Thinking and Living With Cancer Study
  42. Does treatment with resveratrol improve outcomes in patients with Alzheimer's disease?
  43. Polo-like kinase 2 phosphorylation of amyloid precursor protein regulates activity-dependent amyloidogenic processing
  44. Distinct patterns of increased translocator protein in posterior cortical atrophy and amnestic Alzheimer's disease
  45. 11C-PBR28 PET detects translocator protein in a patient with astrocytoma and Alzheimer disease
  46. Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease
  47. The BIOCARD Index
  48. 11C-PBR28 binding to translocator protein increases with progression of Alzheimer's disease
  49. Hexa (ethylene glycol) derivative of benzothiazole aniline promotes dendritic spine formation through the RasGRF1–Ras dependent pathway
  50. An individual with human immunodeficiency virus, dementia, and central nervous system amyloid deposition
  51. A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease
  52. Nilotinib and bosutinib modulate pre-plaque alterations of blood immune markers and neuro-inflammation in Alzheimer’s disease models
  53. Corrigendum to “A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease” [Exp. Neurol. 252 (2014) 105–113]
  54. Cognitive Impairment in Older Patients With Breast Cancer Before Systemic Therapy: Is There an Interaction Between Cancer and Comorbidity?
  55. A tetra(ethylene glycol) derivative of benzothiazole aniline ameliorates dendritic spine density and cognitive function in a mouse model of Alzheimer's disease
  56. Cognitive Effects of Cancer and Its Treatments at the Intersection of Aging: What Do We Know; What Do We Need to Know?
  57. Antihypertensive drug Valsartan promotes dendritic spine density by altering AMPA receptor trafficking
  58. In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease
  59. A Tetra(Ethylene Glycol) Derivative of Benzothiazole Aniline Enhances Ras-Mediated Spinogenesis
  60. Coexisting adult polyglucosan body disease with frontotemporal lobar degeneration with transactivation response DNA-binding protein-43 (TDP-43)-positive neuronal inclusions
  61. Mercaptoacetamide-based class II HDAC inhibitor lowers Aβ levels and improves learning and memory in a mouse model of Alzheimer's disease
  62. Cyclooxygenase-1 inhibition reduces amyloid pathology and improves memory deficits in a mouse model of Alzheimer's disease
  63. Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study
  64. Age-related loss of noradrenergic neurons in the brains of triple transgenic mice
  65. Decreased dendritic spine density and abnormal spine morphology in Fyn knockout mice
  66. Temporoparietal Hypometabolism in Frontotemporal Lobar Degeneration and Associated Imaging Diagnostic Errors
  67. ApoE Receptor 2 Regulates Synapse and Dendritic Spine Formation
  68. Validation of Consensus Panel Diagnosis in Dementia
  69. Beta amyloid-independent role of amyloid precursor protein in generation and maintenance of dendritic spines
  70. ApoE mimetic peptide decreases Aβ production in vitro and in vivo
  71. Therapeutic versus neuroinflammatory effects of passive immunization is dependent on Aβ/amyloid burden in a transgenic mouse model of Alzheimer's disease
  72. ApoE4 Decreases Spine Density and Dendritic Complexity in Cortical Neurons In Vivo
  73. X11α haploinsufficiency enhances Aβ amyloid deposition in Alzheimer's disease transgenic mice
  74. The cytoplasmic adaptor protein X11  and extracellular matrix protein Reelin regulate ApoE receptor 2 trafficking and cell movement
  75. Amyloid-β-Induced Ion Flux in Artificial Lipid Bilayers and Neuronal Cells: Resolving a Controversy
  76. FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease
  77. Alzheimer's Disease
  78. Adaptor protein interactions: modulators of amyloid precursor protein metabolism and Alzheimer's disease risk?
  79. A comparison of classification methods for differentiating fronto-temporal dementia from Alzheimer's disease using FDG-PET imaging
  80. Biomarkers of alzheimer’s disease and mild cognitive impairment: are we there yet?
  81. X11α modulates secretory and endocytic trafficking and metabolism of amyloid precursor protein: mutational analysis of the yenpty sequence
  82. Overexpression of hAPPswe Impairs Rewarded Alternation and Contextual Fear Conditioning in a Transgenic Mouse Model of Alzheimer's Disease
  83. Inherited dementias
  84. Synergistic Effects of Munc18a and X11 Proteins on Amyloid Precursor Protein Metabolism
  85. ELISA analysis of beta-secretase cleavage of the Swedish amyloid precursor protein in the secretory and endocytic pathways
  86. Differentiated Human NT2-N Neurons Possess a High Intracellular Content of myo-Inositol
  87. The Protease Inhibitor, MG132, Blocks Maturation of the Amyloid Precursor Protein Swedish Mutant Preventing Cleavage by β-Secretase
  88. Modulation of Amyloid Precursor Protein Metabolism by X11α/Mint-1
  89. FORUM What Persian Gulf War Syndrome?
  90. Identification of an Evolutionarily Conserved Heterotrimeric Protein Complex Involved in Protein Targeting
  91. The Chaperone BiP/GRP78 Binds to Amyloid Precursor Protein and Decreases Aβ40 and Aβ42 Secretion
  92. X11 Interaction with β-Amyloid Precursor Protein Modulates Its Cellular Stabilization and Reduces Amyloid β-Protein Secretion
  93. The X11α Protein Slows Cellular Amyloid Precursor Protein Processing and Reduces Aβ40 and Aβ42 Secretion
  94. Vaccinia virus serves as an efficient vector for expressing heterologous proteins in human NTera 2 neurons
  95. Clinical, neuroimaging, and pathologic features of progressive nonfluent aphasia
  96. Phospholipid/calcium-dependent protein kinase (protein kinase C) system: A major site of bioregulation
  97. Synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase C)
  98. Phospholipid-Sensitive Ca2+-Dependent Protein Kinase Preferentially Phosphorylates Serine-115 of Bovine Myelin Basic Protein
  99. Developmental studies of phospholipid-sensitive Ca2+-dependent protein kinase and its substrates and of phosphoprotein phosphatases in rat brain.
  100. Phospholipid-sensitive Ca2+-dependent protein kinase: a major protein phosphorylation system
  101. S-100 and Other Acidic Proteins Promote Ca2+-Independent Phosphorylation of Protamine Catalyzed by a New Protein Kinase from Brain
  102. Phospholipid-sensitive Ca2+-dependent protein kinase inhibition by R-24571, A calmodulin antagonist
  103. Comparative abilities of lanthanide ions La3+ and Tb3+ to substitute for Ca2+ in regulating phospholipid-sensitive Ca2+-dependent protein kinase and myosin light chain kinase
  104. Cobra polypeptide cytotoxin I and marine worm polypeptide cytotoxin A-IV are potent and selective inhibitors of phospholipid-sensitive Ca2+ -dependent protein kinase
  105. Basic Protein in Brain Myelin Is Phosphorylated by Endogenous Phospholipid-Sensitive Ca2+-Dependent Protein Kinase
  106. Methionine-enkephalin and morphine: Amount ejected microiontophoretically