Dr Daniel Brewer
University of East Anglia
Lecturer, Medicine And Medical Sciences
United Kingdom
My co-authors include
Professor Ming-Qing Du
Anna Ehinger
adrienne Flanagan
Find me at
My Publications
Detecting new potential lines of attack against prostate cancer based on genetic inform...
Nature Genetics
April 2018
We obtained genetic information from the tumours of 112 men with prostate cancer and pooled it with data from other studies, together analysing samples from 930 prostate cancer patients. A detaile...
Study of mechanisms to "knock out" genes in prostate cancer
PLoS Genetics
September 2017
Cancer is a genetic disease where changes in DNA cause alterations in the control of cellular systems leading to unchecked growth. Copy number changes, including duplications, amplifications, and d...
DESNT: A Poor Prognosis Category of Human Prostate Cancer
European Urology Focus
March 2017
The evolutionary history of lethal metastatic prostate cancer
Nature
April 2015
Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple ind...
Nature Genetics
March 2015
A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prosta...
Clinical Epigenetics
November 2018
The landscape of viral associations in human cancers
November 2018
Mutational signatures of ionizing radiation in second malignancies
Nature Communications
September 2016
Prostate Single Nucleotide Polymorphism Provides a Crucial Clue to Cancer Aggression in...
European Urology
February 2016
Integration of copy number and transcriptomics provides risk stratification in prostate...
EBioMedicine
September 2015
Erratum: Corrigendum: Analysis of the genetic phylogeny of multifocal prostate cancer i...
Nature Genetics
June 2015
Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diag...
Journal of Clinical Pathology
January 2015
HES5 silencing is an early and recurrent change in prostate tumourigenesis
January 2015
Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer
eLife
October 2014
A gene expression based predictor for high risk myeloma treated with intensive therapy ...
Leukemia & Lymphoma
August 2014
Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer...
Science
July 2014
Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer
British Journal of Cancer
January 2014
Benzo pyrene-induced DNA adducts and gene expression profiles in target and non-target ...
BMC Genomics
January 2014
Improved risk stratification in myeloma using a microRNA-based classifier
British Journal of Haematology
May 2013
Prognostic value of PTEN loss in men with conservatively managed localised prostate cancer
British Journal of Cancer
May 2013
Prognostic value of blood mRNA expression signatures in castration-resistant prostate c...
The Lancet Oncology
November 2012
Novel, gross chromosomal alterations involving PTEN cooperate with allelic loss in pros...
Modern Pathology
August 2012
Novel, gross chromosomal alterations involving PTEN cooperate with allelic loss in pros...
Modern Pathology
March 2012
Modelling Transcription Factor Activity
September 2011
A Gene Expression-Based Predictor for Myeloma Patients at High Risk of Developing Bone ...
Clinical Cancer Research
August 2011
siRNA Knockdown of Ribosomal Protein Gene RPL19 Abrogates the Aggressive Phenotype of H...
PLoS ONE
July 2011
A HIF-Regulated VHL-PTP1B-Src Signaling Axis Identifies a Therapeutic Target in Renal C...
Science Translational Medicine
June 2011
PRKC- Expression Promotes the Aggressive Phenotype of Human Prostate Cancer Cells and ...
Genes & Cancer
May 2010
Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low a...
British Journal of Cancer
January 2010
A census of amplified and overexpressed human cancer genes
Nature Reviews Drug Discovery
January 2010
Dissection of a complex transcriptional response using genome-wide transcriptional mode...
Molecular Systems Biology
November 2009
Integration ofERGgene mapping and gene-expression profiling identifies distinct categor...
BJU International
May 2009
Interlaboratory and Interplatform Comparison of Microarray Gene Expression Analysis of ...
OMICS A Journal of Integrative Biology
April 2009
rHVDM: an R package to predict the activity and targets of a transcription factor
Bioinformatics
December 2008
TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical...
British Journal of Cancer
November 2008
Biopsy tissue microarray study of Ki-67 expression in untreated, localized prostate can...
Prostate Cancer and Prostatic Diseases
September 2008
Expression profiling of CD133+and CD133-epithelial cells from human prostate
The Prostate
June 2008
Fitting ordinary differential equations to short time course data
Philosophical Transactions of The Royal Society A Mathematical Physical and Engineering...
February 2008
Detection of TMPRSS2-ERG Translocations in Human Prostate Cancer by Expression Profilin...
Journal of Molecular Diagnostics
January 2008
AHR- and DNA-Damage-Mediated Gene Expression Responses Induced by Benzo(a)pyrene in Hum...
Chemical Research in Toxicology
December 2007
BMC Bioinformatics
January 2006
Genome Biology
January 2006
BMC Genomics
January 2006
Reconstructing gene networks: what are the limits?
Biochemical Society Transactions
December 2003
